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Eugene Redmond

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Cercopithecus aethiops

Chemicals & Drugs

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Animal Behavior

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Co-Publications
Name
50
Roth, Robert
44
Elsworth, John
31
Sladek, John
28
Taylor, Jane
11
Leranth, Csaba
8
Bjugstad, Kimberly
7
Collier, Timothy
6
Jentsch, David
5
Blanchard, Barbara
5
Naftolin, Frederick
5
Deutch, Ariel
4
Snyder, Evan
3
Morrow, Bret
3
teng, yang
3
Bohn, MC

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Publications

TOP 3
Redmond D E; Elsworth J D; Roth R H; Leranth C; Collier T J; Blanchard B; Bjugstad K B; Samulski R J; Aebischer P; Sladek J R
Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF.
Bjugstad Kimberly B; Teng Yang D; Redmond D Eugene; Elsworth John D; Roth Robert H; Cornelius Shannon K; Snyder Evan Y; Sladek John R
Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.
Elsworth J D; Redmond D E; Leranth C; Bjugstad K B; Sladek J R; Collier T J; Foti S B; Samulski R J; Vives K P; Roth R H
AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons.

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All Publications

2009: Redmond D E; Elsworth J D; Roth R H; Leranth C; Collier T J; Blanchard B; Bjugstad K B; Samulski R J; Aebischer P; Sladek J R
Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF.
The Journal of comparative neurology 2009;515(1):31-40.
2008: Bjugstad Kimberly B; Teng Yang D; Redmond D Eugene; Elsworth John D; Roth Robert H; Cornelius Shannon K; Snyder Evan Y; Sladek John R
Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.
Experimental neurology 2008;211(2):362-9.
2008: Elsworth J D; Redmond D E; Leranth C; Bjugstad K B; Sladek J R; Collier T J; Foti S B; Samulski R J; Vives K P; Roth R H
AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons.
Experimental neurology 2008;211(1):252-8.
2008: Elsworth John D; Jentsch J David; Morrow Bret A; Redmond D Eugene; Roth Robert H
Clozapine normalizes prefrontal cortex dopamine transmission in monkeys subchronically exposed to phencyclidine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(3):491-6.
2008: Sladek J R; Bjugstad K B; Collier T J; Bundock E A; Blanchard B C; Elsworth J D; Roth R H; Redmond D E
Embryonic substantia nigra grafts show directional outgrowth to cografted striatal grafts and potential for pathway reconstruction in nonhuman primate.
Cell transplantation 2008;17(4):427-44.
2008: Bjugstad K B; Redmond D E; Lampe K J; Kern D S; Sladek J R; Mahoney M J
Biocompatibility of PEG-based hydrogels in primate brain.
Cell transplantation 2008;17(4):409-15.
2007: Redmond D Eugene; Bjugstad Kimberly B; Teng Yang D; Ourednik Vaclav; Ourednik Jitka; Wakeman Dustin R; Parsons Xuejun H; Gonzalez Rodolfo; Blanchard Barbara C; Kim Seung U; Gu Zezong; Lipton Stuart A; Markakis Eleni A; Roth Robert H; Elsworth John D; Sladek John R; Sidman Richard L; Snyder Evan Y
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12175-80.
2007: Morrow Bret A; Roth Robert H; Redmond D Eugene; Sladek John R; Elsworth John D
Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation.
Experimental neurology 2007;204(2):802-7.
2005: Hackett Neil R; Redmond D Eugene; Sondhi Dolan; Giannaris E Lela; Vassallo Elizabeth; Stratton Jamie; Qiu Jianping; Kaminsky Stephen M; Lesser Martin L; Fisch Gene S; Rouselle Serge D; Crystal Ronald G
Safety of direct administration of AAV2(CU)hCLN2, a candidate treatment for the central nervous system manifestations of late infantile neuronal ceroid lipofuscinosis, to the brain of rats and nonhuman primates.
Human gene therapy 2005;16(12):1484-503.
2005: Markakis Eleni A; Redmond D Eugene
Know thyself: autologous cell transplantation strategies for brain repair.
Experimental neurology 2005;196(1):6-8.
2005: Sondhi D; Peterson D A; Giannaris E L; Sanders C T; Mendez B S; De B; Rostkowski A B; Blanchard B; Bjugstad K; Sladek J R; Redmond D E; Leopold P L; Kaminsky S M; Hackett N R; Crystal R G
AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL.
Gene therapy 2005;12(22):1618-32.
2005: Morrow Bret A; Redmond D Eugene; Roth Robert H; Elsworth John D
Development of A9/A10 dopamine neurons during the second and third trimesters in the African green monkey.
The Journal of comparative neurology 2005;488(2):215-23.
2005: Bjugstad Kimberly B; Redmond D Eugene; Teng Yang D; Elsworth J D; Roth R H; Blanchard B C; Snyder Evan Y; Sladek John R
Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures.
Cell transplantation 2005;14(4):183-92.
2003: Redmond D Eugene; Zhao Ji-Liang; Randall Jeffry D; Eklund Aron C; Eusebi Leonard O V; Roth Robert H; Gullans Steven R; Jensen Roderick V
Spatiotemporal patterns of gene expression during fetal monkey brain development.
Brain research. Developmental brain research 2003;146(1-2):99-106.
2003: Horvath Tamas L; Diano Sabrina; Leranth Csaba; Garcia-Segura Luis Miguel; Cowley Michael A; Shanabrough Marya; Elsworth John D; Sotonyi Peter; Roth Robert H; Dietrich Edwin H; Matthews Russel T; Barnstable Colin J; Redmond D Eugene
Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease.
Endocrinology 2003;144(7):2757-60.
2002: Redmond D Eugene
Cellular replacement therapy for Parkinson's disease--where we are today?
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2002;8(5):457-88.
2002: Park K I; Ourednik J; Ourednik V; Taylor R M; Aboody K S; Auguste K I; Lachyankar M B; Redmond D E; Snyder E Y
Global gene and cell replacement strategies via stem cells.
Gene therapy 2002;9(10):613-24.
2002: Leranth Csaba; Shanabrough Marya; Redmond D Eugene
Gonadal hormones are responsible for maintaining the integrity of spine synapses in the CA1 hippocampal subfield of female nonhuman primates.
The Journal of comparative neurology 2002;447(1):34-42.
2002: Collier Timothy J; Sortwell Caryl E; Elsworth John D; Taylor Jane R; Roth Robert H; Sladek John R; Redmond D Eugene
Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP-treated monkeys: feasibility relevant to multiple-target grafting as a therapy for Parkinson's disease.
The Journal of comparative neurology 2002;442(4):320-30.
2001: Redmond D E; Sladek J R; Spencer D D
Transplantation of embryonic dopamine neurons for severe Parkinson's disease.
The New England journal of medicine 2001;345(2):146-7.
2001: Kozlowski D A; Bremer E; Redmond D E; George D; Larson B; Bohn M C
Quantitative analysis of transgene protein, mRNA, and vector DNA following injection of an adenoviral vector harboring glial cell line-derived neurotrophic factor into the primate caudate nucleus.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(2):256-61.
2000: Leranth C; Roth R H; Elsworth J D; Naftolin F; Horvath T L; Redmond D E
Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: implications for Parkinson's disease and memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(23):8604-9.
2000: Elsworth J D; Taylor J R; Sladek J R; Collier T J; Redmond D E; Roth R H
Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment.
Neuroscience 2000;95(2):399-408.
1999: Lawrence M S; Foellmer H G; Elsworth J D; Kim J H; Leranth C; Kozlowski D A; Bothwell A L; Davidson B L; Bohn M C; Redmond D E
Inflammatory responses and their impact on beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus.
Gene therapy 1999;6(8):1368-79.
1999: Taylor J R; Elsworth J D; Lawrence M S; Sladek J R; Roth R H; Redmond D E
Spontaneous blink rates correlate with dopamine levels in the caudate nucleus of MPTP-treated monkeys.
Experimental neurology 1999;158(1):214-20.
1999: Bohn M C; Choi-Lundberg D L; Davidson B L; Leranth C; Kozlowski D A; Smith J C; O'Banion M K; Redmond D E
Adenovirus-mediated transgene expression in nonhuman primate brain.
Human gene therapy 1999;10(7):1175-84.
1999: Jentsch J D; Taylor J R; Elsworth J D; Redmond D E; Roth R H
Altered frontal cortical dopaminergic transmission in monkeys after subchronic phencyclidine exposure: involvement in frontostriatal cognitive deficits.
Neuroscience 1999;90(3):823-32.
1999: Jentsch J D; Taylor J R; Redmond D E; Elsworth J D; Youngren K D; Roth R H
Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys.
Psychopharmacology 1999;142(1):78-84.
1998: Leranth C; Sladek J R; Roth R H; Redmond D E
Efferent synaptic connections of dopaminergic neurons grafted into the caudate nucleus of experimentally induced parkinsonian monkeys are different from those of control animals.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1998;123(3):323-33.
1998: During M J; Samulski R J; Elsworth J D; Kaplitt M G; Leone P; Xiao X; Li J; Freese A; Taylor J R; Roth R H; Sladek J R; O'Malley K L; Redmond D E
In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector.
Gene therapy 1998;5(6):820-7.
1998: Elsworth J D; Brittan M S; Taylor J R; Sladek J R; Redmond D E; Innis R B; Zea-Ponce Y; Roth R H
Upregulation of striatal D2 receptors in the MPTP-treated vervet monkey is reversed by grafts of fetal ventral mesencephalon: an autoradiographic study.
Brain research 1998;795(1-2):55-62.
1998: Sortwell C E; Blanchard B C; Collier T J; Elsworth J D; Taylor J R; Roth R H; Redmond D E; Sladek J R
Pattern of synaptophysin immunoreactivity within mesencephalic grafts following transplantation in a parkinsonian primate model.
Brain research 1998;791(1-2):117-24.
1998: Sladek J R; Collier T J; Elsworth J D; Roth R H; Taylor J R; Redmond D E
Intrastriatal grafts from multiple donors do not result in a proportional increase in survival of dopamine neurons in nonhuman primates.
Cell transplantation 1998;7(2):87-96.
1998: Jentsch J D; Elsworth J D; Taylor J R; Redmond D E; Roth R H
Dysregulation of mesoprefrontal dopamine neurons induced by acute and repeated phencyclidine administration in the nonhuman primate: implications for schizophrenia.
Advances in pharmacology (San Diego, Calif.) 1998;42():810-4.
1997: Taylor J R; Elsworth J D; Roth R H; Sladek J R; Redmond D E
Severe long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the vervet monkey (Cercopithecus aethiops sabaeus).
Neuroscience 1997;81(3):745-55.
1997: Jentsch J D; Redmond D E; Elsworth J D; Taylor J R; Youngren K D; Roth R H
Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine.
Science (New York, N.Y.) 1997;277(5328):953-5.
1997: Collier T J; Redmond D E; Roth R H; Elsworth J D; Taylor J R; Sladek J R
Metabolic energy capacity of dopaminergic grafts and the implanted striatum in parkinsonian nonhuman primates as visualized with cytochrome oxidase histochemistry.
Cell transplantation 1997;6(2):135-40.
1997: Redmond D E
Gene therapy approaches to Parkinson's disease: preclinical to clinical trials, or what steps to take to get there from here?
Experimental neurology 1997;144(1):160-7.
1997: Jentsch J D; Elsworth J D; Redmond D E; Roth R H
Phencyclidine increases forebrain monoamine metabolism in rats and monkeys: modulation by the isomers of HA966.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(5):1769-75.
1997: Tam S Y; Elsworth J D; Sladek J R; Redmond D E; Roth R H
Identification of novel variants of trkC mRNA transcripts in brain of African green monkeys.
Experimental neurology 1997;143(1):172-6.
1996: Deutch A Y; Lewis D A; Whitehead R E; Elsworth J D; Iadarola M J; Redmond D E; Roth R H
Effects of D2 dopamine receptor antagonists on Fos protein expression in the striatal complex and entorhinal cortex of the nonhuman primate.
Synapse (New York, N.Y.) 1996;23(3):182-91.
1996: Elsworth J D; Sladek J R; Taylor J R; Collier T J; Redmond D E; Roth R H
Early gestational mesencephalon grafts, but not later gestational mesencephalon, cerebellum or sham grafts, increase dopamine in caudate nucleus of MPTP-treated monkeys.
Neuroscience 1996;72(2):477-84.
1996: Elsworth J D; Brittan M S; Taylor J R; Sladek J R; al-Tikriti M S; Zea-Ponce Y; Innis R B; Redmond D E; Roth R H
Restoration of dopamine transporter density in the striatum of fetal ventral mesencephalon-grafted, but not sham-grafted, MPTP-treated parkinsonian monkeys.
Cell transplantation 1996;5(2):315-25.
1995: Taylor J R; Elsworth J D; Sladek J R; Collier T J; Roth R H; Redmond D E
Sham surgery does not ameliorate MPTP-induced behavioral deficits in monkeys.
Cell transplantation 1995;4(1):13-26.
1994: Elsworth J D; al-Tikriti M S; Sladek J R; Taylor J R; Innis R B; Redmond D E; Roth R H
Novel radioligands for the dopamine transporter demonstrate the presence of intrastriatal nigral grafts in the MPTP-treated monkey: correlation with improved behavioral function.
Experimental neurology 1994;126(2):300-4.
1993: Redmond D E; Roth R H; Spencer D D; Naftolin F; Leranth C; Robbins R J; Marek K L; Elsworth J D; Taylor J R; Sass K J
Neural transplantation for neurodegenerative diseases: past, present, and future.
Annals of the New York Academy of Sciences 1993;695():258-66.
1993: Kontur P J; Leranth C; Redmond D E; Roth R H; Robbins R J
Tyrosine hydroxylase immunoreactivity and monoamine and metabolite levels in cryopreserved human fetal ventral mesencephalon.
Experimental neurology 1993;121(2):172-80.
1993: Redmond D E; Robbins R J; Naftolin F; Marek K L; Vollmer T L; Leranth C; Roth R H; Price L H; Gjedde A; Bunney B S
Cellular replacement of dopamine deficit in Parkinson's disease using human fetal mesencephalic tissue: preliminary results in four patients.
Research publications - Association for Research in Nervous and Mental Disease 1993;71():325-59.
1991: Elsworth J D; Lawrence M S; Roth R H; Taylor J R; Mailman R B; Nichols D E; Lewis M H; Redmond D E
D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey.
The Journal of pharmacology and experimental therapeutics 1991;259(2):595-600.
1991: Taylor J R; Lawrence M S; Redmond D E; Elsworth J D; Roth R H; Nichols D E; Mailman R B
Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-induced parkinsonism in monkeys.
European journal of pharmacology 1991;199(3):389-91.
1991: Lawrence M S; Redmond D E
MPTP lesions and dopaminergic drugs alter eye blink rate in African green monkeys.
Pharmacology, biochemistry, and behavior 1991;38(4):869-74.
1991: Taylor J R; Lewis V O; Elsworth J D; Pivirotto P; Roth R H; Redmond D E
Yohimbine co-treatment during chronic morphine administration attenuates naloxone-precipitated withdrawal without diminishing tail-flick analgesia in rats.
Psychopharmacology 1991;103(3):407-14.
1991: Taylor J R; Elsworth J D; Roth R H; Sladek J R; Collier T J; Redmond D E
Grafting of fetal substantia nigra to striatum reverses behavioral deficits induced by MPTP in primates: a comparison with other types of grafts as controls.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1991;85(2):335-48.
1991: Lawrence M S; Redmond D E; Elsworth J D; Taylor J R; Roth R H
The D1 receptor antagonist, SCH 23390, induces signs of parkinsonism in African green monkeys.
Life sciences 1991;49(25):PL229-34.
1990: Taylor J R; Roth R H; Sladek J R; Redmond D E
Cognitive and motor deficits in the performance of an object retrieval task with a barrier-detour in monkeys (Cercopithecus aethiops sabaeus) treated with MPTP: long-term performance and effect of transparency of the barrier.
Behavioral neuroscience 1990;104(4):564-76.
1990: Elsworth J D; Deutch A Y; Redmond D E; Sladek J R; Roth R H
MPTP reduces dopamine and norepinephrine concentrations in the supplementary motor area and cingulate cortex of the primate.
Neuroscience letters 1990;114(3):316-22.
1990: Taylor J R; Elsworth J D; Roth R H; Sladek J R; Redmond D E
Cognitive and motor deficits in the acquisition of an object retrieval/detour task in MPTP-treated monkeys.
Brain : a journal of neurology 1990;113 ( Pt 3)():617-37.
1990: Elsworth J D; Deutch A Y; Redmond D E; Sladek J R; Roth R H
MPTP-induced parkinsonism: relative changes in dopamine concentration in subregions of substantia nigra, ventral tegmental area and retrorubral field of symptomatic and asymptomatic vervet monkeys.
Brain research 1990;513(2):320-4.
1990: Robbins R J; Torres-Aleman I; Lebranth C; Bradberry C W; Deutch A Y; Welsh S; Roth R H; Spencer D; Redmond D E; Naftolin F
Cryopreservation of human brain tissue.
Experimental neurology 1990;107(3):208-13.
1990: Taylor J R; Elsworth J D; Roth R H; Collier T J; Sladek J R; Redmond D E
Improvements in MPTP-induced object retrieval deficits and behavioral deficits after fetal nigral grafting in monkeys.
Progress in brain research 1990;82():543-59.
1989: Elsworth J D; Deutch A Y; Redmond D E; Taylor J R; Sladek J R; Roth R H
Symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates: biochemical changes in striatal regions.
Neuroscience 1989;33(2):323-31.
1988: Redmond D E; Naftolin F; Collier T J; Leranth C; Robbins R J; Sladek C D; Roth R H; Sladek J R
Cryopreservation, culture, and transplantation of human fetal mesencephalic tissue into monkeys.
Science (New York, N.Y.) 1988;242(4879):768-71.
1988: Grant S J; Huang Y H; Redmond D E
Behavior of monkeys during opiate withdrawal and locus coeruleus stimulation.
Pharmacology, biochemistry, and behavior 1988;30(1):13-9.
1988: Taylor J R; Elsworth J D; Garcia E J; Grant S J; Roth R H; Redmond D E
Clonidine infusions into the locus coeruleus attenuate behavioral and neurochemical changes associated with naloxone-precipitated withdrawal.
Psychopharmacology 1988;96(1):121-34.
1980: Grant S J; Huang Y H; Redmond D E
Benzodiazepines attenuate single unit activity in the locus coeruleus.
Life sciences 1980;27(23):2231-6.

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