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Eugene Redmond

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John D Elsworth; Csaba Leranth; D Eugene Redmond; Robert H Roth
Loss of asymmetric spine synapses in prefrontal cortex of motor-asymptomatic, dopamine-depleted, cognitively impaired MPTP-treated monkeys.
Yang D Teng; Dou Yu; Susanna C Benn; Robert H Brown; Bin Cheng; Kadir Erkmen; Inbo Han; Steven N Kalkanis; Mahesh B Lachyankar; Jianxue Li; Jeronia Lládo; Nicholas J Maragakis; Michael Marconi; Renna C Onario; Serge Przedborski; D Eugene Redmond; Jeffrey rothstein; Jeremy M Shefner; Richard L Sidman; Evan Y Snyder
Multimodal actions of neural stem cells in a mouse model of ALS: a meta-analysis.
D Eugene Redmond
Using monkeys to understand and cure Parkinson disease.

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All Publications

2013: John D Elsworth; Csaba Leranth; D Eugene Redmond; Robert H Roth
Loss of asymmetric spine synapses in prefrontal cortex of motor-asymptomatic, dopamine-depleted, cognitively impaired MPTP-treated monkeys.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2013;16(4):905-12.
2012: Yang D Teng; Dou Yu; Susanna C Benn; Robert H Brown; Bin Cheng; Kadir Erkmen; Inbo Han; Steven N Kalkanis; Mahesh B Lachyankar; Jianxue Li; Jeronia Lládo; Nicholas J Maragakis; Michael Marconi; Renna C Onario; Serge Przedborski; D Eugene Redmond; Jeffrey rothstein; Jeremy M Shefner; Richard L Sidman; Evan Y Snyder
Multimodal actions of neural stem cells in a mouse model of ALS: a meta-analysis.
Science translational medicine 2012;4(165):165ra164.
2012: D Eugene Redmond
Using monkeys to understand and cure Parkinson disease.
The Hastings Center report 2012;Suppl():S7-S11.
2012: Victoria DeMartelly; Patrick Hurley; Mathew Lawrence; D Eugene Redmond; Julienne Rutherford
Comparison of fresh to fixed weights of the vervet monkey (Chlorocebus sabaeus) placenta and its relation to gestational age.
Journal of medical primatology 2012;41(3):158-62.
2012: Bret A Morrow; D Eugene Redmond; Robert H Roth; S Diano; John D Elsworth
Susceptibility to a parkinsonian toxin varies during primate development.
Experimental neurology 2012;235(1):273-81.
2012: D Eugene Redmond; Lawrence Evans
Determination of fetal age by ultrasonography in St. Kitts green monkeys.
American journal of primatology 2012;74(5):433-41.
2012: Marcel M Daadi; Brad A Grueter; Robert C Malenka; D Eugene Redmond; Gary K Steinberg
Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease.
PloS one 2012;7(7):e41120.
2011: yang teng; Dustin R Wakeman; Junmei Wang; Dou Yu; Serdar Kabatas; Robert Langer; Jianxue Li; D Eugene Redmond; Alexander E Ropper; Evan Y Snyder; Maryrose P Sullivan; Richard L Sidman
Functional multipotency of stem cells: a conceptual review of neurotrophic factor-based evidence and its role in translational research.
Current neuropharmacology 2011;9(4):574-85.
2010: Eleni A Markakis; Kenneth P Vives; Jeremy Bober; Stefan Leichtle; Csaba Leranth; Jeff Beecham; John D Elsworth; Robert H Roth; R Jude Samulski; D Eugene Redmond
Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(3):588-93.
2009: D Eugene Redmond; John D Elsworth; Robert H Roth; Csaba Leranth; Timothy J Collier; Barbara C Blanchard; Kimberly B Bjugstad; R Jude Samulski; P Aebischer; John R Sladek
Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF.
The Journal of comparative neurology 2009;515(1):31-40.
2008: Kimberly B Bjugstad; yang teng; D Eugene Redmond; John D Elsworth; Robert H Roth; Shannon K Cornelius; Evan Y Snyder; John R Sladek
Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.
Experimental neurology 2008;211(2):362-9.
2008: John D Elsworth; D Eugene Redmond; Csaba Leranth; Kimberly B Bjugstad; John R Sladek; Timothy J Collier; S B Foti; R Jude Samulski; Kenneth P Vives; Robert H Roth
AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons.
Experimental neurology 2008;211(1):252-8.
2008: John D Elsworth; J David Jentsch; Bret A Morrow; D Eugene Redmond; Robert H Roth
Clozapine normalizes prefrontal cortex dopamine transmission in monkeys subchronically exposed to phencyclidine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(3):491-6.
2008: J R Sladek; Kimberly B Bjugstad; Timothy J Collier; E A Bundock; B C Blanchard; John D Elsworth; Robert H Roth; D Eugene Redmond
Embryonic substantia nigra grafts show directional outgrowth to cografted striatal grafts and potential for pathway reconstruction in nonhuman primate.
Cell transplantation 2008;17(4):427-44.
2008: Kimberly B Bjugstad; D Eugene Redmond; K J Lampe; D S Kern; J R Sladek; M J Mahoney
Biocompatibility of PEG-based hydrogels in primate brain.
Cell transplantation 2008;17(4):409-15.
2007: D Eugene Redmond; Kimberly B Bjugstad; yang teng; Václav Ourednik; Jitka Ourednik; Dustin R Wakeman; Xuejun H Parsons; Rodolfo Gonzalez; Barbara C Blanchard; Seung Kim; Zezong Gu; Stuart A Lipton; Eleni A Markakis; Robert H Roth; John D Elsworth; John R Sladek; Richard L Sidman; Evan Y Snyder
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12175-80.
2007: Bret A Morrow; Robert H Roth; D Eugene Redmond; John R Sladek; John D Elsworth
Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation.
Experimental neurology 2007;204(2):802-7.
2005: Neil R Hackett; D Eugene Redmond; Dolan Sondhi; E Lela Giannaris; Elizabeth Vassallo; Jamie Stratton; Jianping Qiu; Stephen M Kaminsky; Martin L Lesser; Gene S Fisch; Serge D Rouselle; Helen-Ann Brown Epstein
Safety of direct administration of AAV2(CU)hCLN2, a candidate treatment for the central nervous system manifestations of late infantile neuronal ceroid lipofuscinosis, to the brain of rats and nonhuman primates.
Human gene therapy 2005;16(12):1484-503.
2005: Eleni A Markakis; D Eugene Redmond
Know thyself: autologous cell transplantation strategies for brain repair.
Experimental neurology 2005;196(1):6-8.
2005: Dolan Sondhi; D A Peterson; E Lela Giannaris; C T Sanders; B S Mendez; B De; A B Rostkowski; Barbara C Blanchard; Kimberly B Bjugstad; John R Sladek; D Eugene Redmond; Philip L Leopold; Stephen M Kaminsky; Neil R Hackett; Helen-Ann Brown Epstein
AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL.
Gene therapy 2005;12(22):1618-32.
2005: Bret A Morrow; D Eugene Redmond; Robert H Roth; John D Elsworth
Development of A9/A10 dopamine neurons during the second and third trimesters in the African green monkey.
The Journal of comparative neurology 2005;488(2):215-23.
2005: Kimberly B Bjugstad; D Eugene Redmond; yang teng; John D Elsworth; Robert H Roth; Barbara C Blanchard; Evan Y Snyder; John R Sladek
Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures.
Cell transplantation 2005;14(4):183-92.
2003: D Eugene Redmond; Ji-Liang Zhao; Jeffry D Randall; Aron C Eklund; Leonard O V Eusebi; Robert H Roth; Steven R Gullans; Roderick V Jensen
Spatiotemporal patterns of gene expression during fetal monkey brain development.
Brain research. Developmental brain research 2003;146(1-2):99-106.
2003: Tamas L Horvath; Sabrina Diano; Csaba Leranth; Luis M Garcia-Segura; Michael Alexander cowley; Marya Shanabrough; John D Elsworth; Peter Sotonyi; Robert H Roth; Edwin H Dietrich; Russell T Matthews; Colin J Barnstable; D Eugene Redmond
Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease.
Endocrinology 2003;144(7):2757-60.
2002: D Eugene Redmond
Cellular replacement therapy for Parkinson's disease--where we are today?
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2002;8(5):457-88.
2002: Csaba Leranth; Marya Shanabrough; D Eugene Redmond
Gonadal hormones are responsible for maintaining the integrity of spine synapses in the CA1 hippocampal subfield of female nonhuman primates.
The Journal of comparative neurology 2002;447(1):34-42.
2002: Kook In Park; Jitka Ourednik; Václav Ourednik; R M Taylor; Karen S Aboody; K I Auguste; Mahesh Lachyankar; D Eugene Redmond; Evan Y Snyder
Global gene and cell replacement strategies via stem cells.
Gene therapy 2002;9(10):613-24.
2002: Timothy J Collier; Caryl E Sortwell; John D Elsworth; Jane R Taylor; Robert H Roth; John R Sladek; D Eugene Redmond
Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP-treated monkeys: feasibility relevant to multiple-target grafting as a therapy for Parkinson's disease.
The Journal of comparative neurology 2002;442(4):320-30.
2001: D Eugene Redmond; John R Sladek; D D Spencer
Transplantation of embryonic dopamine neurons for severe Parkinson's disease.
The New England journal of medicine 2001;345(2):146-7.
2001: DA Kozlowski; Eric G Bremer; D Eugene Redmond; David George; B Larson; MC Bohn
Quantitative analysis of transgene protein, mRNA, and vector DNA following injection of an adenoviral vector harboring glial cell line-derived neurotrophic factor into the primate caudate nucleus.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(2):256-61.
2000: Csaba Leranth; Robert H Roth; John D Elsworth; Frederick Naftolin; Tamas L Horvath; D Eugene Redmond
Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: implications for Parkinson's disease and memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(23):8604-9.
2000: John D Elsworth; Jane R Taylor; John R Sladek; Timothy J Collier; D Eugene Redmond; Robert H Roth
Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment.
Neuroscience 2000;95(2):399-408.
1999: M S Lawrence; Harald G Foellmer; John D Elsworth; J H Kim; Csaba Leranth; DA Kozlowski; Alfred L M Bothwell; BL Davidson; MC Bohn; D Eugene Redmond
Inflammatory responses and their impact on beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus.
Gene therapy 1999;6(8):1368-79.
1999: Jane R Taylor; John D Elsworth; M S Lawrence; John R Sladek; Robert H Roth; D Eugene Redmond
Spontaneous blink rates correlate with dopamine levels in the caudate nucleus of MPTP-treated monkeys.
Experimental neurology 1999;158(1):214-20.
1999: MC Bohn; DL Choi-Lundberg; BL Davidson; Csaba Leranth; DA Kozlowski; J C Smith; M K O'Banion; D Eugene Redmond
Adenovirus-mediated transgene expression in nonhuman primate brain.
Human gene therapy 1999;10(7):1175-84.
1999: J David Jentsch; Jane R Taylor; John D Elsworth; D Eugene Redmond; Robert H Roth
Altered frontal cortical dopaminergic transmission in monkeys after subchronic phencyclidine exposure: involvement in frontostriatal cognitive deficits.
Neuroscience 1999;90(3):823-32.
1999: J David Jentsch; Jane R Taylor; D Eugene Redmond; John D Elsworth; KD Youngren; Robert H Roth
Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys.
Psychopharmacology 1999;142(1):78-84.
1998: Csaba Leranth; John R Sladek; Robert H Roth; D Eugene Redmond
Efferent synaptic connections of dopaminergic neurons grafted into the caudate nucleus of experimentally induced parkinsonian monkeys are different from those of control animals.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1998;123(3):323-33.
1998: John D Elsworth; M S Brittan; Jane R Taylor; John R Sladek; D Eugene Redmond; Robert B Innis; Yolanda Zea-Ponce; Robert H Roth
Upregulation of striatal D2 receptors in the MPTP-treated vervet monkey is reversed by grafts of fetal ventral mesencephalon: an autoradiographic study.
Brain research 1998;795(1-2):55-62.
1998: Matthew J During; R Jude Samulski; John D Elsworth; Michael Gordon Kaplitt; Paola Leone; Xiao Xiao; J Li; Andrew Freese; Jane R Taylor; Robert H Roth; John R Sladek; Karen L O'Malley; D Eugene Redmond
In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector.
Gene therapy 1998;5(6):820-7.
1998: Caryl E Sortwell; Barbara C Blanchard; Timothy J Collier; John D Elsworth; Jane R Taylor; Robert H Roth; D Eugene Redmond; John R Sladek
Pattern of synaptophysin immunoreactivity within mesencephalic grafts following transplantation in a parkinsonian primate model.
Brain research 1998;791(1-2):117-24.
1998: John R Sladek; Timothy J Collier; John D Elsworth; Robert H Roth; Jane R Taylor; D Eugene Redmond
Intrastriatal grafts from multiple donors do not result in a proportional increase in survival of dopamine neurons in nonhuman primates.
Cell transplantation 1998;7(2):87-96.
1998: J David Jentsch; John D Elsworth; Jane R Taylor; D Eugene Redmond; Robert H Roth
Dysregulation of mesoprefrontal dopamine neurons induced by acute and repeated phencyclidine administration in the nonhuman primate: implications for schizophrenia.
Advances in pharmacology (San Diego, Calif.) 1998;42():810-4.
1997: Jane R Taylor; John D Elsworth; Robert H Roth; John R Sladek; D Eugene Redmond
Severe long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the vervet monkey (Cercopithecus aethiops sabaeus).
Neuroscience 1997;81(3):745-55.
1997: J David Jentsch; D Eugene Redmond; John D Elsworth; Jane R Taylor; KD Youngren; Robert H Roth
Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine.
Science (New York, N.Y.) 1997;277(5328):953-5.
1997: Timothy J Collier; D Eugene Redmond; Robert H Roth; John D Elsworth; Jane R Taylor; John R Sladek
Metabolic energy capacity of dopaminergic grafts and the implanted striatum in parkinsonian nonhuman primates as visualized with cytochrome oxidase histochemistry.
Cell transplantation 1997;6(2):135-40.
1997: D Eugene Redmond
Gene therapy approaches to Parkinson's disease: preclinical to clinical trials, or what steps to take to get there from here?
Experimental neurology 1997;144(1):160-7.
1997: J David Jentsch; John D Elsworth; D Eugene Redmond; Robert H Roth
Phencyclidine increases forebrain monoamine metabolism in rats and monkeys: modulation by the isomers of HA966.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(5):1769-75.
1997: S Y Tam; John D Elsworth; John R Sladek; D Eugene Redmond; Robert H Roth
Identification of novel variants of trkC mRNA transcripts in brain of African green monkeys.
Experimental neurology 1997;143(1):172-6.
1996: Ariel Deutch; D A Lewis; R E Whitehead; John D Elsworth; Michael Iadarola; D Eugene Redmond; Robert H Roth
Effects of D2 dopamine receptor antagonists on Fos protein expression in the striatal complex and entorhinal cortex of the nonhuman primate.
Synapse (New York, N.Y.) 1996;23(3):182-91.
1996: John D Elsworth; John R Sladek; Jane R Taylor; Timothy J Collier; D Eugene Redmond; Robert H Roth
Early gestational mesencephalon grafts, but not later gestational mesencephalon, cerebellum or sham grafts, increase dopamine in caudate nucleus of MPTP-treated monkeys.
Neuroscience 1996;72(2):477-84.
1996: John D Elsworth; M S Brittan; Jane R Taylor; John R Sladek; Mohammed S Al-Tikriti; Yolanda Zea-Ponce; Robert B Innis; D Eugene Redmond; Robert H Roth
Restoration of dopamine transporter density in the striatum of fetal ventral mesencephalon-grafted, but not sham-grafted, MPTP-treated parkinsonian monkeys.
Cell transplantation 1996;5(2):315-25.
1995: Jane R Taylor; John D Elsworth; John R Sladek; Timothy J Collier; Robert H Roth; D Eugene Redmond
Sham surgery does not ameliorate MPTP-induced behavioral deficits in monkeys.
Cell transplantation 1995;4(1):13-26.
1994: John D Elsworth; Mohammed S Al-Tikriti; John R Sladek; Jane R Taylor; Robert B Innis; D Eugene Redmond; Robert H Roth
Novel radioligands for the dopamine transporter demonstrate the presence of intrastriatal nigral grafts in the MPTP-treated monkey: correlation with improved behavioral function.
Experimental neurology 1994;126(2):300-4.
1993: D Eugene Redmond; Robert H Roth; Dennis D Spencer; Frederick Naftolin; Csaba Leranth; R J Robbins; Kenneth Marek; John D Elsworth; Jane R Taylor; K J Sass
Neural transplantation for neurodegenerative diseases: past, present, and future.
Annals of the New York Academy of Sciences 1993;695():258-66.
1993: P J Kontur; Csaba Leranth; D Eugene Redmond; Robert H Roth; R J Robbins
Tyrosine hydroxylase immunoreactivity and monoamine and metabolite levels in cryopreserved human fetal ventral mesencephalon.
Experimental neurology 1993;121(2):172-80.
1993: D Eugene Redmond; R J Robbins; Frederick Naftolin; Kenneth Marek; T L Vollmer; Csaba Leranth; Robert H Roth; Lawrence H Price; Albert Gjedde; B S Bunney
Cellular replacement of dopamine deficit in Parkinson's disease using human fetal mesencephalic tissue: preliminary results in four patients.
Research publications - Association for Research in Nervous and Mental Disease 1993;71():325-59.
1991: John D Elsworth; M S Lawrence; Robert H Roth; Jane R Taylor; Richard B Mailman; D E Nichols; M H Lewis; D Eugene Redmond
D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey.
The Journal of pharmacology and experimental therapeutics 1991;259(2):595-600.
1991: Jane R Taylor; M S Lawrence; D Eugene Redmond; John D Elsworth; Robert H Roth; D E Nichols; Richard B Mailman
Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-induced parkinsonism in monkeys.
European journal of pharmacology 1991;199(3):389-91.
1991: M S Lawrence; D Eugene Redmond
MPTP lesions and dopaminergic drugs alter eye blink rate in African green monkeys.
Pharmacology, biochemistry, and behavior 1991;38(4):869-74.
1991: Jane R Taylor; V O Lewis; John D Elsworth; P Pivirotto; Robert H Roth; D Eugene Redmond
Yohimbine co-treatment during chronic morphine administration attenuates naloxone-precipitated withdrawal without diminishing tail-flick analgesia in rats.
Psychopharmacology 1991;103(3):407-14.
1991: Jane R Taylor; John D Elsworth; Robert H Roth; John R Sladek; Timothy J Collier; D Eugene Redmond
Grafting of fetal substantia nigra to striatum reverses behavioral deficits induced by MPTP in primates: a comparison with other types of grafts as controls.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1991;85(2):335-48.
1991: M S Lawrence; D Eugene Redmond; John D Elsworth; Jane R Taylor; Robert H Roth
The D1 receptor antagonist, SCH 23390, induces signs of parkinsonism in African green monkeys.
Life sciences 1991;49(25):PL229-34.
1990: Jane R Taylor; Robert H Roth; John R Sladek; D Eugene Redmond
Cognitive and motor deficits in the performance of an object retrieval task with a barrier-detour in monkeys (Cercopithecus aethiops sabaeus) treated with MPTP: long-term performance and effect of transparency of the barrier.
Behavioral neuroscience 1990;104(4):564-76.
1990: John D Elsworth; Ariel Deutch; D Eugene Redmond; John R Sladek; Robert H Roth
MPTP reduces dopamine and norepinephrine concentrations in the supplementary motor area and cingulate cortex of the primate.
Neuroscience letters 1990;114(3):316-22.
1990: Jane R Taylor; John D Elsworth; Robert H Roth; John R Sladek; D Eugene Redmond
Cognitive and motor deficits in the acquisition of an object retrieval/detour task in MPTP-treated monkeys.
Brain : a journal of neurology 1990;113 ( Pt 3)():617-37.
1990: John D Elsworth; Ariel Deutch; D Eugene Redmond; John R Sladek; Robert H Roth
MPTP-induced parkinsonism: relative changes in dopamine concentration in subregions of substantia nigra, ventral tegmental area and retrorubral field of symptomatic and asymptomatic vervet monkeys.
Brain research 1990;513(2):320-4.
1990: R J Robbins; I Torres-Aleman; C Lebranth; Charles W Bradberry; Ariel Deutch; S Welsh; Robert H Roth; D Spencer; D Eugene Redmond; Frederick Naftolin
Cryopreservation of human brain tissue.
Experimental neurology 1990;107(3):208-13.
1990: Jane R Taylor; John D Elsworth; Robert H Roth; Timothy J Collier; John R Sladek; D Eugene Redmond
Improvements in MPTP-induced object retrieval deficits and behavioral deficits after fetal nigral grafting in monkeys.
Progress in brain research 1990;82():543-59.
1989: John D Elsworth; Ariel Deutch; D Eugene Redmond; Jane R Taylor; John R Sladek; Robert H Roth
Symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates: biochemical changes in striatal regions.
Neuroscience 1989;33(2):323-31.
1988: D Eugene Redmond; Frederick Naftolin; Timothy J Collier; C Leranth; R J Robbins; C D Sladek; Robert H Roth; John R Sladek
Cryopreservation, culture, and transplantation of human fetal mesencephalic tissue into monkeys.
Science (New York, N.Y.) 1988;242(4879):768-71.
1988: S J Grant; Y H Huang; D Eugene Redmond
Behavior of monkeys during opiate withdrawal and locus coeruleus stimulation.
Pharmacology, biochemistry, and behavior 1988;30(1):13-9.
1988: Jane R Taylor; John D Elsworth; E J Garcia; S J Grant; Robert H Roth; D Eugene Redmond
Clonidine infusions into the locus coeruleus attenuate behavioral and neurochemical changes associated with naloxone-precipitated withdrawal.
Psychopharmacology 1988;96(1):121-34.
1980: S J Grant; Y H Huang; D Eugene Redmond
Benzodiazepines attenuate single unit activity in the locus coeruleus.
Life sciences 1980;27(23):2231-6.