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John Reed

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Crisóstomo Fernando R Pinacho; Feng Yongmei; Zhu Xuejun; Welsh Kate; An Jing; Reed John C; Huang Ziwei
Design and synthesis of a simplified inhibitor for XIAP-BIR3 domain.
Krieg Andreas; Correa Ricardo G; Garrison Jason B; Le Negrate Gaëlle; Welsh Kate; Huang Ziwei; Knoefel Wolfram T; Reed John C
XIAP mediates NOD signaling via interaction with RIP2.
Chan Siew Leong; Low Lieh Yoon; Hsu Simon; Li Sheng; Liu Tong; Santelli Eugenio; Le Negrate Gaelle; Reed John C; Woods Virgil L; Pascual Jaime
Molecular mimicry in innate immunity: crystal structure of a bacterial TIR domain.

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All Publications

2009: Crisóstomo Fernando R Pinacho; Feng Yongmei; Zhu Xuejun; Welsh Kate; An Jing; Reed John C; Huang Ziwei
Design and synthesis of a simplified inhibitor for XIAP-BIR3 domain.
Bioorganic & medicinal chemistry letters 2009;19(22):6413-8.
2009: Krieg Andreas; Correa Ricardo G; Garrison Jason B; Le Negrate Gaëlle; Welsh Kate; Huang Ziwei; Knoefel Wolfram T; Reed John C
XIAP mediates NOD signaling via interaction with RIP2.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14524-9.
2009: Chan Siew Leong; Low Lieh Yoon; Hsu Simon; Li Sheng; Liu Tong; Santelli Eugenio; Le Negrate Gaelle; Reed John C; Woods Virgil L; Pascual Jaime
Molecular mimicry in innate immunity: crystal structure of a bacterial TIR domain.
The Journal of biological chemistry 2009;284(32):21386-92.
2009: Wei Jun; Kitada Shinichi; Rega Michele F; Stebbins John L; Zhai Dayong; Cellitti Jason; Yuan Hongbin; Emdadi Aras; Dahl Russell; Zhang Ziming; Yang Li; Reed John C; Pellecchia Maurizio
Apogossypol derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.
Journal of medicinal chemistry 2009;52(14):4511-23.
2009: Dawson Marcia I; Ye Mao; Cao Xihua; Farhana Lulu; Hu Qiong-Ying; Zhao Yong; Xu Li Ping; Kiselyuk Alice; Correa Ricardo G; Yang Li; Hou Tingjun; Reed John C; Itkin-Ansari Pamela; Levine Fred; Sanner Michel F; Fontana Joseph A; Zhang Xiao-Kun
Derivation of a retinoid X receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene.
ChemMedChem 2009;4(7):1106-19.
2009: Krajewska Maryla; Smith Layton H; Rong Juan; Huang Xianshu; Hyer Marc L; Zeps Nikolajs; Iacopetta Barry; Linke Steven P; Olson Allen H; Reed John C; Krajewski Stan
Image analysis algorithms for immunohistochemical assessment of cell death events and fibrosis in tissue sections.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009;57(7):649-63.
2009: Zapata Juan M; Llobet David; Krajewska Maryla; Lefebvre Sophie; Kress Christina L; Reed John C
Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancer.
Blood 2009;113(19):4595-603.
2009: Loeffler Markus; Le'Negrate Gaelle; Krajewska Maryla; Reed John C
Salmonella typhimurium engineered to produce CCL21 inhibit tumor growth.
Cancer immunology, immunotherapy : CII 2009;58(5):769-75.
2009: Wei Jun; Kitada Shinichi; Rega Michele F; Emdadi Aras; Yuan Hongbin; Cellitti Jason; Stebbins John L; Zhai Dayong; Sun Jiazhi; Yang Li; Dahl Russell; Zhang Ziming; Wu Bainan; Wang Si; Reed Tyler A; Wang Hong-Gang; Lawrence Nicholas; Sebti Said; Reed John C; Pellecchia Maurizio
Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins.
Molecular cancer therapeutics 2009;8(4):904-13.
2009: Garrison J B; Samuel T; Reed J C
TRAF2-binding BIR1 domain of c-IAP2/MALT1 fusion protein is essential for activation of NF-kappaB.
Oncogene 2009;28(13):1584-93.
2009: Faustin Benjamin; Chen Ya; Zhai Dayong; Le Negrate Gaelle; Lartigue Lydia; Satterthwait Arnold; Reed John C
Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3935-40.
2009: Krieg Andreas; Le Negrate Gaëlle; Reed John C
RIP2-beta: a novel alternative mRNA splice variant of the receptor interacting protein kinase RIP2.
Molecular immunology 2009;46(6):1163-70.
2009: Kim InKi; Shu Chih-Wen; Xu Wenjie; Shiau Chung-Wai; Grant Daniel; Vasile Stefan; Cosford Nicholas D P; Reed John C
Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.
The Journal of biological chemistry 2009;284(3):1593-603.
2009: Princen Frederic; Bard Emilie; Sheikh Farah; Zhang Sharon S; Wang Jing; Zago Wagner M; Wu Dongmei; Trelles Ramon Diaz; Bailly-Maitre Beatrice; Kahn C Ronald; Chen Yan; Reed John C; Tong Gary G; Mercola Mark; Chen Ju; Feng Gen-Sheng
Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature death.
Molecular and cellular biology 2009;29(2):378-88.
2009: Wei Jun; Rega Michele F; Kitada Shinichi; Yuan Hongbin; Zhai Dayong; Risbood Prabhakar; Seltzman Herbert H; Twine Charles E; Reed John C; Pellecchia Maurizio
Synthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists.
Cancer letters 2009;273(1):107-13.
2009: Hayashi Hideki; Cuddy Michael; Shu Vincent Chih-Wen; Yip Kenneth W; Madiraju Charitha; Diaz Paul; Matsuyama Toshifumi; Kaibara Muneshige; Taniyama Kohtaro; Vasile Stefan; Sergienko Eduard; Reed John C
Versatile assays for high throughput screening for activators or inhibitors of intracellular proteases and their cellular regulators.
PloS one 2009;4(10):e7655.
2008: Calzolari Diego; Bruschi Stefania; Coquin Laurence; Schofield Jennifer; Feala Jacob D; Reed John C; McCulloch Andrew D; Paternostro Giovanni
Search algorithms as a framework for the optimization of drug combinations.
PLoS computational biology 2008;4(12):e1000249.
2008: Kim Inki; Xu Wenjie; Reed John C
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities.
Nature reviews. Drug discovery 2008;7(12):1013-30.
2008: Rohde G; Kermer P; Reed J C; Bähr M; Weishaupt J H
Neuron-specific overexpression of the co-chaperone Bcl-2-associated athanogene-1 in superoxide dismutase 1(G93A)-transgenic mice.
Neuroscience 2008;157(4):844-9.
2008: Bisson William H; Zhang Ziming; Welsh Kate; Huang Jui-Wen; Ryan Jennifer; Reed John C; Pellecchia Maurizio
Binding properties of the C-terminal domain of VIAF.
Chemical biology & drug design 2008;72(5):331-6.
2008: Huang Jui-Wen; Zhang Ziming; Wu Bainan; Cellitti Jason F; Zhang Xiyun; Dahl Russell; Shiau Chung-Wai; Welsh Kate; Emdadi Aras; Stebbins John L; Reed John C; Pellecchia Maurizio
Fragment-based design of small molecule X-linked inhibitor of apoptosis protein inhibitors.
Journal of medicinal chemistry 2008;51(22):7111-8.
2008: Yip K W; Reed J C
Bcl-2 family proteins and cancer.
Oncogene 2008;27(50):6398-406.
2008: Reed J C
Apoptosis and cell death. Foreword.
Oncogene 2008;27(48):6192-3.
2008: Le Negrate Gaëlle; Krieg Andreas; Faustin Benjamin; Loeffler Markus; Godzik Adam; Krajewski Stan; Reed John C
ChlaDub1 of Chlamydia trachomatis suppresses NF-kappaB activation and inhibits IkappaBalpha ubiquitination and degradation.
Cellular microbiology 2008;10(9):1879-92.
2008: Loeffler Markus; Le'Negrate Gaelle; Krajewska Maryla; Reed John C
Inhibition of tumor growth using salmonella expressing Fas ligand.
Journal of the National Cancer Institute 2008;100(15):1113-6.
2008: Yip Kenneth W; Godoi Paulo H C; Zhai Dayong; Garcia Xochella; Cellitti Jason F; Cuddy Michael; Gerlic Motti; Chen Ya; Satterthwait Arnold; Vasile Stefan; Sergienko Eduard; Reed John C
A TR3/Nur77 peptide-based high-throughput fluorescence polarization screen for small molecule Bcl-B inhibitors.
Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening 2008;13(7):665-73.
2008: Zhai Dayong; Jin Chaofang; Shiau Chung-Wai; Kitada Shinichi; Satterthwait Arnold C; Reed John C
Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins.
Molecular cancer therapeutics 2008;7(6):1639-46.
2008: Zhou G; Xie T-X; Zhao M; Jasser S A; Younes M N; Sano D; Lin J; Kupferman M E; Santillan A A; Patel V; Gutkind J S; Ei-Naggar A K; Emberley E D; Watson P H; Matsuzawa S-I; Reed J C; Myers J N
Reciprocal negative regulation between S100A7/psoriasin and beta-catenin signaling plays an important role in tumor progression of squamous cell carcinoma of oral cavity.
Oncogene 2008;27(25):3527-38.
2008: Krajewska Maryla; Kitada Shinichi; Winter Jane N; Variakojis Daina; Lichtenstein Alan; Zhai Dayong; Cuddy Michael; Huang Xianshu; Luciano Frederic; Baker Cheryl H; Kim Hoguen; Shin Eunah; Kennedy Susan; Olson Allen H; Badzio Andrzej; Jassem Jacek; Meinhold-Heerlein Ivo; Duffy Michael J; Schimmer Aaron D; Tsao Ming; Brown Ewan; Sawyers Anne; Andreeff Michael; Mercola Dan; Krajewski Stan; Reed John C
Bcl-B expression in human epithelial and nonepithelial malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(10):3011-21.
2008: Hyer Marc L; Shi Ranxin; Krajewska Maryla; Meyer Colin; Lebedeva Irina V; Fisher Paul B; Reed John C
Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
Cancer research 2008;68(8):2927-33.
2008: Puto Lorena A; Reed John C
Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation.
Genes & development 2008;22(8):998-1010.
2008: Reed John C
Bcl-2-family proteins and hematologic malignancies: history and future prospects.
Blood 2008;111(7):3322-30.
2008: Le Negrate Gaëlle; Faustin Benjamin; Welsh Kate; Loeffler Markus; Krajewska Maryla; Hasegawa Patty; Mukherjee Sohini; Orth Kim; Krajewski Stan; Godzik Adam; Guiney Donald G; Reed John C
Salmonella secreted factor L deubiquitinase of Salmonella typhimurium inhibits NF-kappaB, suppresses IkappaBalpha ubiquitination and modulates innate immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):5045-56.
2008: Xu Chunyan; Xu Wenjie; Palmer Amy E; Reed John C
BI-1 regulates endoplasmic reticulum Ca2+ homeostasis downstream of Bcl-2 family proteins.
The Journal of biological chemistry 2008;283(17):11477-84.
2008: Zhai Dayong; Jin Chaofang; Huang Ziwei; Satterthwait Arnold C; Reed John C
Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.
The Journal of biological chemistry 2008;283(15):9580-6.
2008: Liman Jan; Faida Lena; Dohm Christoph P; Reed John C; Bähr Mathias; Kermer Pawel
Subcellular distribution affects BAG1 function.
Brain research 2008;1198():21-6.
2008: Wen Yunfei; Golubkov Vladislav S; Strongin Alex Y; Jiang Wei; Reed John C
Interaction of hepatitis B viral oncoprotein with cellular target HBXIP dysregulates centrosome dynamics and mitotic spindle formation.
The Journal of biological chemistry 2008;283(5):2793-803.
2008: Faustin Benjamin; Reed John C
Sunburned skin activates inflammasomes.
Trends in cell biology 2008;18(1):4-8.
2007: Dorfleutner Andrea; Talbott Siera J; Bryan Nicole B; Funya Kristin N; Rellick Stephanie L; Reed John C; Shi Xianglin; Rojanasakul Yon; Flynn Daniel C; Stehlik Christian
A Shope Fibroma virus PYRIN-only protein modulates the host immune response.
Virus genes 2007;35(3):685-94.
2007: Santoro Massimo M; Samuel Temesgen; Mitchell Tracy; Reed John C; Stainier Didier Y R
Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis.
Nature genetics 2007;39(11):1397-402.
2007: Choi Jungyuen; Zhai Dayong; Zhou Xin; Satterthwait Arnold; Reed John C; Marassi Francesca M
Mapping the specific cytoprotective interaction of humanin with the pro-apoptotic protein bid.
Chemical biology & drug design 2007;70(5):383-92.
2007: Loeffler Markus; Le'Negrate Gaelle; Krajewska Maryla; Reed John C
Attenuated Salmonella engineered to produce human cytokine LIGHT inhibit tumor growth.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(31):12879-83.
2007: Krajewska Maryla; Olson Allen H; Mercola Dan; Reed John C; Krajewski Stan
Claudin-1 immunohistochemistry for distinguishing malignant from benign epithelial lesions of prostate.
The Prostate 2007;67(9):907-10.
2007: Mawji Imtiaz A; Simpson Craig D; Hurren Rose; Gronda Marcela; Williams Moyo A; Filmus Jorge; Jonkman James; Da Costa Ralph S; Wilson Brian C; Thomas Michael P; Reed John C; Glinsky Gennadi V; Schimmer Aaron D
Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation.
Journal of the National Cancer Institute 2007;99(10):811-22.
2007: Luciano Frederic; Krajewska Maryla; Ortiz-Rubio Paulina; Krajewski Stan; Zhai Dayong; Faustin Benjamin; Bruey Jean-Marie; Bailly-Maitre Beatrice; Lichtenstein Alan; Kolluri Siva Kumar; Satterthwait Arnold C; Zhang Xiao-Kun; Reed John C
Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma.
Blood 2007;109(9):3849-55.
2007: Bruey Jean-Marie; Bruey-Sedano Nathalie; Luciano Frederic; Zhai Dayong; Balpai Ruchi; Xu Chunyan; Kress Christina L; Bailly-Maitre Beatrice; Li Xiaoqing; Osterman Andrei; Matsuzawa Shu-ichi; Terskikh Alexey V; Faustin Benjamin; Reed John C
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1.
Cell 2007;129(1):45-56.
2007: Fukushima Toru; Matsuzawa Shu-ichi; Kress Christina L; Bruey Jean Marie; Krajewska Maryla; Lefebvre Sophie; Zapata Juan M; Ronai Ze'ev; Reed John C
Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6371-6.
2007: Mukasa Takashi; Santelli Eugenio; Reed John C; Pascual Jaime
Preliminary structural studies on the leucine-zipper homology region of the human protein Bap31.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 4):297-9.
2007: Rega Michele F; Reed John C; Pellecchia Maurizio
Robust lanthanide-based assays for the detection of anti-apoptotic Bcl-2-family protein antagonists.
Bioorganic chemistry 2007;35(2):113-20.
2007: Faustin Benjamin; Lartigue Lydia; Bruey Jean-Marie; Luciano Frederic; Sergienko Eduard; Bailly-Maitre Beatrice; Volkmann Niels; Hanein Dorit; Rouiller Isabelle; Reed John C
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation.
Molecular cell 2007;25(5):713-24.
2007: Dorfleutner Andrea; Bryan Nicole B; Talbott Siera J; Funya Kristin N; Rellick Stephanie L; Reed John C; Shi Xianglin; Rojanasakul Yon; Flynn Daniel C; Stehlik Christian
Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation.
Infection and immunity 2007;75(3):1484-92.
2007: Bailly-Maitre Béatrice; Bard-Chapeau Emilie; Luciano Fréderic; Droin Nathalie; Bruey Jean-Marie; Faustin Benjamin; Kress Christina; Zapata Juan M; Reed John C
Mice lacking bi-1 gene show accelerated liver regeneration.
Cancer research 2007;67(4):1442-50.
2007: Kim Hyung-Ryong; Chae Han-Jung; Thomas Michael; Miyazaki Tadaaki; Monosov Anna; Monosov Edward; Krajewska Maryla; Krajewski Stan; Reed John C
Mammalian dap3 is an essential gene required for mitochondrial homeostasis in vivo and contributing to the extrinsic pathway for apoptosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(1):188-96.
2007: Aoyagi Mika; Zhai Dayong; Jin Chaofang; Aleshin Alexander E; Stec Boguslaw; Reed John C; Liddington Robert C
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein.
Protein science : a publication of the Protein Society 2007;16(1):118-24.
2007: Matsuzawa Shu-ichi; Reed John C
Yeast and mammalian two-hybrid systems for studying protein-protein interactions.
Methods in molecular biology (Clifton, N.J.) 2007;383():215-25.
2007: Zapata Juan M; Lefebvre Sophie; Reed John C
Targeting TRAfs for therapeutic intervention.
Advances in experimental medicine and biology 2007;597():188-201.
2007: Kress Christina L; Konopleva Marina; Martínez-García Vanesa; Krajewska Maryla; Lefebvre Sophie; Hyer Marc L; McQueen Teresa; Andreeff Michael; Reed John C; Zapata Juan M
Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma.
PloS one 2007;2(6):e559.
2006: Laine Aaron; Topisirovic Ivan; Zhai Dayong; Reed John C; Borden Katherine L B; Ronai Ze'ev
Regulation of p53 localization and activity by Ubc13.
Molecular and cellular biology 2006;26(23):8901-13.
2006: Konopleva Marina; Contractor Rooha; Tsao Twee; Samudio Ismael; Ruvolo Peter P; Kitada Shinichi; Deng Xingming; Zhai Dayong; Shi Yue-Xi; Sneed Thomas; Verhaegen Monique; Soengas Maria; Ruvolo Vivian R; McQueen Teresa; Schober Wendy D; Watt Julie C; Jiffar Tilahun; Ling Xiaoyang; Marini Frank C; Harris David; Dietrich Martin; Estrov Zeev; McCubrey James; May W Stratford; Reed John C; Andreeff Michael
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Cancer cell 2006;10(5):375-88.
2006: Hyer Marc L; Samuel Temesgen; Reed John C
The FLIP-side of Fas signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 1):5929-31.
2006: Fujii Ryoji; Zhu Changjun; Wen Yunfei; Marusawa Hiroyuki; Bailly-Maitre Beatrice; Matsuzawa Shu-ichi; Zhang Hong; Kim Youngsoo; Bennett C Frank; Jiang Wei; Reed John C
HBXIP, cellular target of hepatitis B virus oncoprotein, is a regulator of centrosome dynamics and cytokinesis.
Cancer research 2006;66(18):9099-107.
2006: Croxton Rhonda; Puto Lorena A; de Belle Ian; Thomas Michael; Torii Seiji; Hanaii Farid; Cuddy Michael; Reed John C
Daxx represses expression of a subset of antiapoptotic genes regulated by nuclear factor-kappaB.
Cancer research 2006;66(18):9026-35.
2006: Homma Sachiko; Iwasaki Masahiro; Shelton G Diane; Engvall Eva; Reed John C; Takayama Shinichi
BAG3 deficiency results in fulminant myopathy and early lethality.
The American journal of pathology 2006;169(3):761-73.
2006: Becattini Barbara; Culmsee Carsten; Leone Marilisa; Zhai Dayong; Zhang Xiyun; Crowell Kevin J; Rega Michele F; Landshamer Stefan; Reed John C; Plesnila Nikolaus; Pellecchia Maurizio
Structure-activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12602-6.
2006: Reed J C
Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities.
Cell death and differentiation 2006;13(8):1378-86.
2006: Reed John C
Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms.
Nature clinical practice. Oncology 2006;3(7):388-98.
2006: Krajewska Maryla; Turner Bruce C; Shabaik Ahmed; Krajewski Stan; Reed John C
Expression of BAG-1 protein correlates with aggressive behavior of prostate cancers.
The Prostate 2006;66(8):801-10.
2006: Schimmer Aaron D; Thomas Michael P; Hurren Rose; Gronda Marcela; Pellecchia Maurizio; Pond Gregory R; Konopleva Marina; Gurfinkel Debbie; Mawji Imtiaz A; Brown Ewan; Reed John C
Identification of small molecules that sensitize resistant tumor cells to tumor necrosis factor-family death receptors.
Cancer research 2006;66(4):2367-75.
2006: Bailly-Maitre Béatrice; Fondevila Constantino; Kaldas Fady; Droin Nathalie; Luciano Fréderic; Ricci Jean-Ehrland; Croxton Rhonda; Krajewska Maryla; Zapata Juan M; Kupiec-Weglinski Jerzy W; Farmer Douglas; Reed John C
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2809-14.
2006: Fukushima Toru; Zapata Juan M; Singha Netai C; Thomas Michael; Kress Christina L; Krajewska Maryla; Krajewski Stan; Ronai Ze'ev; Reed John C; Matsuzawa Shu-Ichi
Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint.
Immunity 2006;24(1):29-39.
2006: Newman Ruchi M; Salunkhe Prabhakar; Godzik Adam; Reed John C
Identification and characterization of a novel bacterial virulence factor that shares homology with mammalian Toll/interleukin-1 receptor family proteins.
Infection and immunity 2006;74(1):594-601.
2006: Samuel Temesgen; Welsh Kate; Lober Thomas; Togo Summanuna H; Zapata Juan M; Reed John C
Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases.
The Journal of biological chemistry 2006;281(2):1080-90.
2006: Dohm Christoph P; Siedenberg Sandra; Liman Jan; Esposito Alessandro; Wouters Fred S; Reed John C; Bähr Mathias; Kermer Pawel
Bax inhibitor-1 protects neurons from oxygen-glucose deprivation.
Journal of molecular neuroscience : MN 2006;29(1):1-8.
2005: Matsuzawa Shu-ichi; Cuddy Michael; Fukushima Toru; Reed John C
Method for targeting protein destruction by using a ubiquitin-independent, proteasome-mediated degradation pathway.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(42):14982-7.
2005: Xu Chunyan; Bailly-Maitre Beatrice; Reed John C
Endoplasmic reticulum stress: cell life and death decisions.
The Journal of clinical investigation 2005;115(10):2656-64.
2005: Santelli Eugenio; Leone Marilisa; Li Chenlong; Fukushima Toru; Preece Nicholas E; Olson Arthur J; Ely Kathryn R; Reed John C; Pellecchia Maurizio; Liddington Robert C; Matsuzawa Shu-ichi
Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex.
The Journal of biological chemistry 2005;280(40):34278-87.
2005: Wu ShuangDing; Xie Ping; Welsh Kate; Li Chenglong; Ni Chao-Zhou; Zhu Xiuwen; Reed John C; Satterthwait Arnold C; Bishop Gail A; Ely Kathryn R
LMP1 protein from the Epstein-Barr virus is a structural CD40 decoy in B lymphocytes for binding to TRAF3.
The Journal of biological chemistry 2005;280(39):33620-6.
2005: Krajewska Maryla; Kim Hoguen; Shin Eunah; Kennedy Susan; Duffy Michael J; Wong Yick F; Marr David; Mikolajczyk Jowita; Shabaik Ahmed; Meinhold-Heerlein Ivo; Huang Xianshu; Banares Steven; Hedayat Hirad; Reed John C; Krajewski Stan
Tumor-associated alterations in caspase-14 expression in epithelial malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(15):5462-71.
2005: Krajewska Maryla; Kim Hoguen; Kim Chul; Kang Haeyoun; Welsh Kate; Matsuzawa Shu-Ichi; Tsukamoto Michelle; Thomas Ronald G; Assa-Munt Nuria; Piao Zhe; Suzuki Koichi; Perucho Manuel; Krajewski Stan; Reed John C
Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(15):5451-61.
2005: Hyer Marc L; Croxton Rhonda; Krajewska Maryla; Krajewski Stanislaw; Kress Christina L; Lu Meiling; Suh Nanjoo; Sporn Michael B; Cryns Vincent L; Zapata Juan M; Reed John C
Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.
Cancer research 2005;65(11):4799-808.
2005: Liman Jan; Ganesan Sundar; Dohm Christoph P; Krajewski Stan; Reed John C; Bähr Mathias; Wouters Fred S; Kermer Pawel
Interaction of BAG1 and Hsp70 mediates neuroprotectivity and increases chaperone activity.
Molecular and cellular biology 2005;25(9):3715-25.
2005: Banares Steven; Zeh Karin; Krajewska Maryla; Kermer Pawel; Baribault Helene; Reed John C; Krajewski Stan
Novel pan-neuronal Cre-transgenic line for conditional ablation of genes in the nervous system.
Genesis (New York, N.Y. : 2000) 2005;42(1):6-16.
2005: Carter Bing Z; Gronda Marcela; Wang Zhiliang; Welsh Kate; Pinilla Clemencia; Andreeff Michael; Schober Wendy D; Nefzi Adel; Pond Gregory R; Mawji Imtiaz A; Houghten Richard A; Ostresh John; Brandwein Joseph; Minden Mark D; Schuh Andre C; Wells Richard A; Messner Hans; Chun Kathy; Reed John C; Schimmer Aaron D
Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.
Blood 2005;105(10):4043-50.
2005: Zhai Dayong; Luciano Frederic; Zhu Xiuwen; Guo Bin; Satterthwait Arnold C; Reed John C
Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak.
The Journal of biological chemistry 2005;280(16):15815-24.
2005: Luciano Frederic; Zhai Dayong; Zhu Xiuwen; Bailly-Maitre Beatrice; Ricci Jean-Ehrland; Satterthwait Arnold C; Reed John C
Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL.
The Journal of biological chemistry 2005;280(16):15825-35.
2005: Chan Henry; Reed John C
TRAF-dependent association of protein kinase Tpl2/COT1 (MAP3K8) with CD40.
Biochemical and biophysical research communications 2005;328(1):198-205.
2005: Samuel Temesgen; Okada Kazuya; Hyer Marc; Welsh Kate; Zapata Juan M; Reed John C
cIAP1 Localizes to the nuclear compartment and modulates the cell cycle.
Cancer research 2005;65(1):210-8.
2004: Ni Chao-Zhou; Oganesyan Gagik; Welsh Kate; Zhu Xiuwen; Reed John C; Satterthwait Arnold C; Cheng Genhong; Ely Kathryn R
Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7394-400.
2004: Bruey Jean Marie; Bruey-Sedano Nathalie; Newman Ruchi; Chandler Sharon; Stehlik Christian; Reed John C
PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages.
The Journal of biological chemistry 2004;279(50):51897-907.
2004: Reed John C
Apoptosis mechanisms: implications for cancer drug discovery.
Oncology (Williston Park, N.Y.) 2004;18(13 Suppl 10):11-20.
2004: Zapata Juan M; Krajewska Maryla; Morse Herbert C; Choi Yongwon; Reed John C
TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(47):16600-5.
2004: Damiano Jason S; Newman Ruchi M; Reed John C
Multiple roles of CLAN (caspase-associated recruitment domain, leucine-rich repeat, and NAIP CIIA HET-E, and TP1-containing protein) in the mammalian innate immune response.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6338-45.
2004: Wang Zhiliang; Cuddy Michael; Samuel Temesgen; Welsh Kate; Schimmer Aaron; Hanaii Farid; Houghten Richard; Pinilla Clemencia; Reed John C
Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors.
The Journal of biological chemistry 2004;279(46):48168-76.
2004: Krajewska Maryla; Rosenthal Robert E; Mikolajczyk Jowita; Stennicke Henning R; Wiesenthal Thomas; Mai Juergen; Naito Mikihiko; Salvesen Guy S; Reed John C; Fiskum Gary; Krajewski Stan
Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation.
Experimental neurology 2004;189(2):261-79.
2004: Miyazaki Tadaaki; Shen Min; Fujikura Daisuke; Tosa Noriko; Kim Hyung-Ryong; Kon Shigeyuki; Uede Toshimitsu; Reed John C
Functional role of death-associated protein 3 (DAP3) in anoikis.
The Journal of biological chemistry 2004;279(43):44667-72.
2004: Stehlik Christian; Reed John C
The PYRIN connection: novel players in innate immunity and inflammation.
The Journal of experimental medicine 2004;200(5):551-8.
2004: Becattini Barbara; Sareth Sina; Zhai Dayong; Crowell Kevin J; Leone Marilisa; Reed John C; Pellecchia Maurizio
Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules.
Chemistry & biology 2004;11(8):1107-17.
2004: Chae Han-Jung; Kim Hyung-Ryong; Xu Chunyan; Bailly-Maitre Beatrice; Krajewska Maryla; Krajewski Stan; Banares Steven; Cui Janice; Digicaylioglu Murat; Ke Ning; Kitada Shinichi; Monosov Edward; Thomas Michael; Kress Christina L; Babendure Jeremy R; Tsien Roger Y; Lipton Stuart A; Reed John C
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress.
Molecular cell 2004;15(3):355-66.
2004: Dohi Takehiko; Okada Kazuya; Xia Fang; Wilford Casey E; Samuel Temesgen; Welsh Kate; Marusawa Hiroyouki; Zou Hua; Armstrong Robert; Matsuzawa Shu-ichi; Salvesen Guy S; Reed John C; Altieri Dario C
An IAP-IAP complex inhibits apoptosis.
The Journal of biological chemistry 2004;279(33):34087-90.
2004: Schwarzenbacher Robert; Stenner-Liewen Frank; Liewen Heike; Reed John C; Liddington Robert C
Crystal structure of PqqC from Klebsiella pneumoniae at 2.1 A resolution.
Proteins 2004;56(2):401-3.
2004: Pedersen Irene M; Zapata Juan M; Samuel Temesgen; Scott Fiona L; Salvesen Guy S; Honda Tadashi; Gribble Gordon W; Suh Nanjoo; Sporn Michael B; Kipps Thomas J; Reed John C
Retraction: The triterpenoid CDDO-Imidazolide induces apoptosis and enhances fludarabine-induced apoptosis of CLL B-cells.
Blood 2004;104(4):932.
2004: Gong Xiao-Min; Choi Jungyuen; Franzin Carla M; Zhai Dayong; Reed John C; Marassi Francesca M
Conformation of membrane-associated proapoptotic tBid.
The Journal of biological chemistry 2004;279(28):28954-60.
2004: Damiano Jason S; Oliveira Vasco; Welsh Kate; Reed John C
Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses.
The Biochemical journal 2004;381(Pt 1):213-9.
2004: Schwarzenbacher Robert; Stenner-Liewen Frank; Liewen Heike; Robinson Howard; Yuan Hua; Bossy-Wetzel Ella; Reed John C; Liddington Robert C
Structure of the Chlamydia protein CADD reveals a redox enzyme that modulates host cell apoptosis.
The Journal of biological chemistry 2004;279(28):29320-4.
2004: Reed John C; Doctor Kutbuddin S; Godzik Adam
The domains of apoptosis: a genomics perspective.
Science's STKE : signal transduction knowledge environment 2004;2004(239):re9.
2004: Damiano Jason S; Reed John C
CARD proteins as therapeutic targets in cancer.
Current drug targets 2004;5(4):367-74.
2004: Becattini Barbara; Kitada Shinichi; Leone Marilisa; Monosov Edward; Chandler Sharon; Zhai Dayong; Kipps Thomas J; Reed John C; Pellecchia Maurizio
Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).
Chemistry & biology 2004;11(3):389-95.
2004: Lin Bingzhen; Kolluri Siva Kumar; Lin Feng; Liu Wen; Han Young-Hoon; Cao Xihua; Dawson Marcia I; Reed John C; Zhang Xiao-kun
Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3.
Cell 2004;116(4):527-40.
2004: Franzin Carla M; Choi Jungyuen; Zhai Dayong; Reed John C; Marassi Francesca M
Structural studies of apoptosis and ion transport regulatory proteins in membranes.
Magnetic resonance in chemistry : MRC 2004;42(2):172-9.
2004: Schimmer Aaron D; Welsh Kate; Pinilla Clemencia; Wang Zhiliang; Krajewska Maryla; Bonneau Marie-Josee; Pedersen Irene M; Kitada Shinichi; Scott Fiona L; Bailly-Maitre Beatrice; Glinsky Gennadi; Scudiero Dominick; Sausville Edward; Salvesen Guy; Nefzi Adel; Ostresh John M; Houghten Richard A; Reed John C
Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity.
Cancer cell 2004;5(1):25-35.
2004: Cirman Tina; Oresic Kristina; Mazovec Gabriela Droga; Turk Vito; Reed John C; Myers Richard M; Salvesen Guy S; Turk Boris
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins.
The Journal of biological chemistry 2004;279(5):3578-87.
2004: Pusztai Lajos; Krishnamurti Savitri; Perez Cardona Jorge; Sneige Nour; Esteva Francisco J; Volchenok Marina; Breitenfelder Patricia; Kau Shu-Wan; Takayama Shin; Krajewski Stanislaw; Reed John C; Bast Robert C; Hortobagyi Gabriel N
Expression of BAG-1 and BcL-2 proteins before and after neoadjuvant chemotherapy of locally advanced breast cancer.
Cancer investigation 2004;22(2):248-56.
2004: Pellecchia Maurizio; Reed John C
Inhibition of anti-apoptotic Bcl-2 family proteins by natural polyphenols: new avenues for cancer chemoprevention and chemotherapy.
Current pharmaceutical design 2004;10(12):1387-98.
2004: Andreeff M; Milella M; Carter B Z; Tabe Y; Ricciardi M R; Sneed T; Ruvolo P; Contractor R; Tsao T; Schober W; Evans R; McQueen T; Zeng Z; Kornblau S M; McCubrey J; Estey E; Mills G B; Reed J C; Konopleva M
Targeted therapy of AML new concepts.
Annals of hematology 2004;83 Suppl 1():S51-3.
2004: Roth Wilfried; Reed John C
FLIP protein and TRAIL-induced apoptosis.
Vitamins and hormones 2004;67():189-206.
2003: Reed John C; Wilson Darcy B
Cancer immunotherapy targeting survivin: commentary re: V. Pisarev et al., full-length dominant-negative survivin for cancer immunotherapy. Clin. Cancer Res., 9:6523-6533, 2003.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(17):6310-5.
2003: Leone Marilisa; Zhai Dayong; Sareth Sina; Kitada Shinichi; Reed John C; Pellecchia Maurizio
Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins.
Cancer research 2003;63(23):8118-21.
2003: Takayama Shinichi; Reed John C; Homma Sachiko
Heat-shock proteins as regulators of apoptosis.
Oncogene 2003;22(56):9041-7.
2003: Chae Han-Jung; Ke Ning; Kim Hyung-Ryong; Chen Shaorong; Godzik Adam; Dickman Martin; Reed John C
Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast.
Gene 2003;323():101-13.
2003: Stehlik Christian; Lee Sug Hyung; Dorfleutner Andrea; Stassinopoulos Angela; Sagara Junji; Reed John C
Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):6154-63.
2003: Li Chenglong; Norris Paula S; Ni Chao-Zhou; Havert Marnie L; Chiong Elizabeth M; Tran Bonnie R; Cabezas Edelmira; Reed John C; Satterthwait Arnold C; Ware Carl F; Ely Kathryn R
Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling.
The Journal of biological chemistry 2003;278(50):50523-9.
2003: Carter Bing Z; Kornblau Steven M; Tsao Twee; Wang Rui-Yu; Schober Wendy D; Milella Michele; Sung Hsi-Guang; Reed John C; Andreeff Michael
Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis.
Blood 2003;102(12):4179-86.
2003: Suh W-S; Kim Y S; Schimmer A D; Kitada S; Minden M; Andreeff M; Suh N; Sporn M; Reed J C
Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(11):2122-9.
2003: Zhai Dayong; Ke Ning; Zhang Haichao; Ladror Uri; Joseph Mary; Eichinger Andreas; Godzik Adam; Ng Shi-Chung; Reed John C
Characterization of the anti-apoptotic mechanism of Bcl-B.
The Biochemical journal 2003;376(Pt 1):229-36.
2003: Kermer Pawel; Digicaylioglu Murat H; Kaul Marcus; Zapata Juan M; Krajewska Maryla; Stenner-Liewen Frank; Takayama Shinichi; Krajewski Stan; Lipton Stuart A; Reed John C
BAG1 over-expression in brain protects against stroke.
Brain pathology (Zurich, Switzerland) 2003;13(4):495-506.
2003: Krajewska Maryla; Krajewski Stan; Banares Steven; Huang Xianshu; Turner Bruce; Bubendorf Lukas; Kallioniemi Olli-P; Shabaik Ahmed; Vitiello Antonella; Peehl Donna; Gao Guo-Jian; Reed John C
Elevated expression of inhibitor of apoptosis proteins in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):4914-25.
2003: Roth W; Kermer P; Krajewska M; Welsh K; Davis S; Krajewski S; Reed J C
Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways.
Cell death and differentiation 2003;10(10):1178-87.
2003: Kitada Shinichi; Leone Marilisa; Sareth Sina; Zhai Dayong; Reed John C; Pellecchia Maurizio
Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins.
Journal of medicinal chemistry 2003;46(20):4259-64.
2003: Kawai Taro; Akira Shizuo; Reed John C
ZIP kinase triggers apoptosis from nuclear PML oncogenic domains.
Molecular and cellular biology 2003;23(17):6174-86.
2003: Stehlik Christian; Hayashi Hideki; Pio Frederick; Godzik Adam; Reed John C
CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways.
The Journal of biological chemistry 2003;278(34):31941-9.
2003: Shin Hwain; Okada Kazuya; Wilkinson John C; Solomon Katherine M; Duckett Colin S; Reed John C; Salvesen Guy S
Identification of ubiquitination sites on the X-linked inhibitor of apoptosis protein.
The Biochemical journal 2003;373(Pt 3):965-71.
2003: Stehlik Christian; Krajewska Maryla; Welsh Kate; Krajewski Stanislaw; Godzik Adam; Reed John C
The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation.
The Biochemical journal 2003;373(Pt 1):101-13.
2003: Reed John C; Doctor Kutbuddin; Rojas Ana; Zapata Juan M; Stehlik Christian; Fiorentino Loredana; Damiano Jason; Roth Wilfried; Matsuzawa Shu-Ichi; Newman Ruchi; Takayama Shinichi; Marusawa Hiroyuki; Xu Famming; Salvesen Guy; Godzik Adam;
Comparative analysis of apoptosis and inflammation genes of mice and humans.
Genome research 2003;13(6B):1376-88.
2003: Marusawa Hiroyuki; Matsuzawa Shu-Ichi; Welsh Kate; Zou Hua; Armstrong Robert; Tamm Ingo; Reed John C
HBXIP functions as a cofactor of survivin in apoptosis suppression.
The EMBO journal 2003;22(11):2729-40.
2003: Doctor K S; Reed J C; Godzik A; Bourne P E
The apoptosis database.
Cell death and differentiation 2003;10(6):621-33.
2003: Schimmer Aaron D; Munk-Pedersen Irene; Minden Mark D; Reed John C
Bcl-2 and apoptosis in chronic lymphocytic leukemia.
Current treatment options in oncology 2003;4(3):211-8.
2003: Guo Bin; Zhai Dayong; Cabezas Edelmira; Welsh Kate; Nouraini Shahrzad; Satterthwait Arnold C; Reed John C
Humanin peptide suppresses apoptosis by interfering with Bax activation.
Nature 2003;423(6938):456-61.
2003: Eksioglu-Demiralp Emel; Kitada Shinichi; Carson Denise; Garland John; Andreef Michael; Reed John C
A method for functional evaluation of caspase activation pathways in intact lymphoid cells using electroporation-mediated protein delivery and flow cytometric analysis.
Journal of immunological methods 2003;275(1-2):41-56.
2003: Tamm Ingo; Trepel Martin; Cardó-Vila Marina; Sun Yan; Welsh Kate; Cabezas Edelmira; Swatterthwait Arnold; Arap Wadih; Reed John C; Pasqualini Renata
Peptides targeting caspase inhibitors.
The Journal of biological chemistry 2003;278(16):14401-5.
2003: Schimmer Aaron D; Pedersen Irene Munk; Kitada Shinichi; Eksioglu-Demiralp Emel; Minden Mark D; Pinto Ryan; Mah Ken; Andreeff Michael; Kim Youngsoo; Suh Won Suk; Reed John C
Functional blocks in caspase activation pathways are common in leukemia and predict patient response to induction chemotherapy.
Cancer research 2003;63(6):1242-8.
2003: Reed John C
Apoptosis-targeted therapies for cancer.
Cancer cell 2003;3(1):17-22.
2003: Matsuzawa Shu-ichi; Li Chenglong; Ni Chao-Zhou; Takayama Shinichi; Reed John C; Ely Kathryn R
Structural analysis of Siah1 and its interactions with Siah-interacting protein (SIP).
The Journal of biological chemistry 2003;278(3):1837-40.
2002: Stehlik Christian; Fiorentino Loredana; Dorfleutner Andrea; Bruey Jean-Marie; Ariza Eugenia M; Sagara Junji; Reed John C
The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways.
The Journal of experimental medicine 2002;196(12):1605-15.
2002: Decary Stephanie; Decesse Julien T; Ogryzko Vasily; Reed John C; Naguibneva Irina; Harel-Bellan Annick; Cremisi Chantal E
The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2.
Molecular and cellular biology 2002;22(22):7877-88.
2002: Pedersen Irene M; Kitada Shinichi; Schimmer Aaron; Kim Youngsoo; Zapata Juan M; Charboneau Lula; Rassenti Laura; Andreeff Michael; Bennett Frank; Sporn Michael B; Liotta Lance D; Kipps Thomas J; Reed John C
The triterpenoid CDDO induces apoptosis in refractory CLL B cells.
Blood 2002;100(8):2965-72.
2002: Pedersen Irene M; Kitada Shinichi; Leoni Lorenzo M; Zapata Juan M; Karras James G; Tsukada Nobuhiro; Kipps Thomas J; Choi Yong Sung; Bennett Frank; Reed John C
Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1.
Blood 2002;100(5):1795-801.
2002: Fiorentino Loredana; Stehlik Christian; Oliveira Vasco; Ariza Maria Eugenia; Godzik Adam; Reed John C
A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta.
The Journal of biological chemistry 2002;277(38):35333-40.
2002: Konopleva Marina; Zhao Shourong; Hu Wei; Jiang Shuwei; Snell Virginia; Weidner Douglas; Jackson C Ellen; Zhang Xin; Champlin Richard; Estey Elihu; Reed John C; Andreeff Michael
The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells.
British journal of haematology 2002;118(2):521-34.
2002: Ni Chao Zhou; Welsh Kate; Zheng Jianhua; Havert Marnie; Reed John C; Ely Kathryn R
Crystallization and preliminary X-ray analysis of the TRAF domain of TRAF3.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 8):1340-2.
2002: Narisawa Sonoko; Hecht Norman B; Goldberg Erwin; Boatright Kelly M; Reed John C; Millán José Luis
Testis-specific cytochrome c-null mice produce functional sperm but undergo early testicular atrophy.
Molecular and cellular biology 2002;22(15):5554-62.
2002: Guzey Meral; Kitada Shinichi; Reed John C
Apoptosis induction by 1alpha,25-dihydroxyvitamin D3 in prostate cancer.
Molecular cancer therapeutics 2002;1(9):667-77.
2002: Jin Can; Reed John C
Yeast and apoptosis.
Nature reviews. Molecular cell biology 2002;3(6):453-9.
2002: Kim Youngsoo; Suh Nanjoo; Sporn Michael; Reed John C
An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis.
The Journal of biological chemistry 2002;277(25):22320-9.
2002: Kitada Shinichi; Pedersen Irene M; Schimmer Aaron D; Reed John C
Dysregulation of apoptosis genes in hematopoietic malignancies.
Oncogene 2002;21(21):3459-74.
2002: Kermer P; Krajewska M; Zapata J M; Takayama S; Mai J; Krajewski S; Reed J C
Bag1 is a regulator and marker of neuronal differentiation.
Cell death and differentiation 2002;9(4):405-13.
2002: Li Chenglong; Ni Chao-Zhou; Havert Marnie L; Cabezas Edelmira; He Jeannie; Kaiser Donald; Reed John C; Satterthwait Arnold C; Cheng Genhong; Ely Kathryn R
Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure (London, England : 1993) 2002;10(3):403-11.
2002: Kudoh Masafumi; Knee Deborah A; Takayama Shinichi; Reed John C
Bag1 proteins regulate growth and survival of ZR-75-1 human breast cancer cells.
Cancer research 2002;62(6):1904-9.
2002: Krajewska Maryla; Zapata Juan M; Meinhold-Heerlein Ivo; Hedayat Hirad; Monks Anne; Bettendorf Herta; Shabaik Ahmed; Bubendorf Lukas; Kallioniemi Olli-P; Kim Hoguen; Reifenberger Guido; Reed John C; Krajewski Stanislaw
Expression of Bcl-2 family member Bid in normal and malignant tissues.
Neoplasia (New York, N.Y.) 2002;4(2):129-40.
2002: Stenner-Liewen Frank; Liewen Heike; Zapata Juan M; Pawlowski Krzysztof; Godzik Adam; Reed John C
CADD, a Chlamydia protein that interacts with death receptors.
The Journal of biological chemistry 2002;277(12):9633-6.
2002: Roth Wilfried; Stenner-Liewen Frank; Pawlowski Krzysztof; Godzik Adam; Reed John C
Identification and characterization of DEDD2, a death effector domain-containing protein.
The Journal of biological chemistry 2002;277(9):7501-8.
2002: Reed John C; Kitada Shinichi; Kim Youngsoo; Byrd John
Modulating apoptosis pathways in low-grade B-cell malignancies using biological response modifiers.
Seminars in oncology 2002;29(1 Suppl 2):10-24.
2002: Krajewska M; Mai J K; Zapata J M; Ashwell K W S; Schendel S L; Reed J C; Krajewski S
Dynamics of expression of apoptosis-regulatory proteins Bid, Bcl-2, Bcl-X, Bax and Bak during development of murine nervous system.
Cell death and differentiation 2002;9(2):145-57.
2002: Reed John C; Green Douglas R
Remodeling for demolition: changes in mitochondrial ultrastructure during apoptosis.
Molecular cell 2002;9(1):1-3.
2001: Brive L; Takayama S; Briknarová K; Homma S; Ishida S K; Reed J C; Ely K R
The carboxyl-terminal lobe of Hsc70 ATPase domain is sufficient for binding to BAG1.
Biochemical and biophysical research communications 2001;289(5):1099-105.
2001: Pathan N; Aime-Sempe C; Kitada S; Basu A; Haldar S; Reed J C
Microtubule-targeting drugs induce bcl-2 phosphorylation and association with Pin1.
Neoplasia (New York, N.Y.) 2001;3(6):550-9.
2001: Takayama S; Reed J C
Molecular chaperone targeting and regulation by BAG family proteins.
Nature cell biology 2001;3(10):E237-41.
2001: Reed J C
The Survivin saga goes in vivo.
The Journal of clinical investigation 2001;108(7):965-9.
2001: Lee S H; Stehlik C; Reed J C
Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing.
The Journal of biological chemistry 2001;276(37):34495-500.
2001: Pathan N; Marusawa H; Krajewska M; Matsuzawa S; Kim H; Okada K; Torii S; Kitada S; Krajewski S; Welsh K; Pio F; Godzik A; Reed J C
TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.
The Journal of biological chemistry 2001;276(34):32220-9.
2001: Chen M; He H; Zhan S; Krajewski S; Reed J C; Gottlieb R A
Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion.
The Journal of biological chemistry 2001;276(33):30724-8.
2001: Damiano J S; Stehlik C; Pio F; Godzik A; Reed J C
CLAN, a novel human CED-4-like gene.
Genomics 2001;75(1-3):77-83.
2001: Miyazaki T; Reed J C
A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins.
Nature immunology 2001;2(6):493-500.
2001: Zapata J M; Pawlowski K; Haas E; Ware C F; Godzik A; Reed J C
A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains.
The Journal of biological chemistry 2001;276(26):24242-52.
2001: Matsuzawa S I; Reed J C
Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses.
Molecular cell 2001;7(5):915-26.
2001: Paternostro G; Vignola C; Bartsch D U; Omens J H; McCulloch A D; Reed J C
Age-associated cardiac dysfunction in Drosophila melanogaster.
Circulation research 2001;88(10):1053-8.
2001: Meinhold-Heerlein I; Stenner-Liewen F; Liewen H; Kitada S; Krajewska M; Krajewski S; Zapata J M; Monks A; Scudiero D A; Bauknecht T; Reed J C
Expression and potential role of Fas-associated phosphatase-1 in ovarian cancer.
The American journal of pathology 2001;158(4):1335-44.
2001: Knee D A; Froesch B A; Nuber U; Takayama S; Reed J C
Structure-function analysis of Bag1 proteins. Effects on androgen receptor transcriptional activity.
The Journal of biological chemistry 2001;276(16):12718-24.
2001: Ke N; Godzik A; Reed J C
Bcl-B, a novel Bcl-2 family member that differentially binds and regulates Bax and Bak.
The Journal of biological chemistry 2001;276(16):12481-4.
2001: Briknarová K; Takayama S; Brive L; Havert M L; Knee D A; Velasco J; Homma S; Cabezas E; Stuart J; Hoyt D W; Satterthwait A C; Llinás M; Reed J C; Ely K R
Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein.
Nature structural biology 2001;8(4):349-52.
2001: Chu Z L; Pio F; Xie Z; Welsh K; Krajewska M; Krajewski S; Godzik A; Reed J C
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis.
The Journal of biological chemistry 2001;276(12):9239-45.
2001: Leo E; Deveraux Q L; Buchholtz C; Welsh K; Matsuzawa S; Stennicke H R; Salvesen G S; Reed J C
TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis.
The Journal of biological chemistry 2001;276(11):8087-93.
2001: Deveraux Q L; Schendel S L; Reed J C
Antiapoptotic proteins. The bcl-2 and inhibitor of apoptosis protein families.
Cardiology clinics 2001;19(1):57-74.
2001: Pawlowski K; Pio F; Chu Z; Reed J C; Godzik A
PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases.
Trends in biochemical sciences 2001;26(2):85-7.
2001: Stoka V; Turk B; Schendel S L; Kim T H; Cirman T; Snipas S J; Ellerby L M; Bredesen D; Freeze H; Abrahamson M; Bromme D; Krajewski S; Reed J C; Yin X M; Turk V; Salvesen G S
Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route.
The Journal of biological chemistry 2001;276(5):3149-57.
2001: Pathan N; Aime-Sempe C; Kitada S; Haldar S; Reed J C
Microtubule-targeting drugs induce Bcl-2 phosphorylation and association with Pin1.
Neoplasia (New York, N.Y.) 2001;3(1):70-9.
2001: Guo B; Godzik A; Reed J C
Bcl-G, a novel pro-apoptotic member of the Bcl-2 family.
The Journal of biological chemistry 2001;276(4):2780-5.
2000: Matsuyama S; Reed J C
Mitochondria-dependent apoptosis and cellular pH regulation.
Cell death and differentiation 2000;7(12):1155-65.
2000: Guzey M; Takayama S; Reed J C
BAG1L enhances trans-activation function of the vitamin D receptor.
The Journal of biological chemistry 2000;275(52):40749-56.
2000: Reed J C
Mechanisms of apoptosis.
The American journal of pathology 2000;157(5):1415-30.
2000: Zapata J M; Krajewska M; Krajewski S; Kitada S; Welsh K; Monks A; McCloskey N; Gordon J; Kipps T J; Gascoyne R D; Shabaik A; Reed J C
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5084-96.
2000: Reed J C; Bischoff J R
BIRinging chromosomes through cell division--and survivin' the experience.
Cell 2000;102(5):545-8.
2000: Ni C Z; Welsh K; Leo E; Chiou C K; Wu H; Reed J C; Ely K R
Molecular basis for CD40 signaling mediated by TRAF3.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(19):10395-9.
2000: Ionov Y; Yamamoto H; Krajewski S; Reed J C; Perucho M
Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(20):10872-7.
2000: Zhang H; Huang Q; Ke N; Matsuyama S; Hammock B; Godzik A; Reed J C
Drosophila pro-apoptotic Bcl-2/Bax homologue reveals evolutionary conservation of cell death mechanisms.
The Journal of biological chemistry 2000;275(35):27303-6.
2000: Li H; Kolluri S K; Gu J; Dawson M I; Cao X; Hobbs P D; Lin B; Chen G; Lu J; Lin F; Xie Z; Fontana J A; Reed J C; Zhang X
Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.
Science (New York, N.Y.) 2000;289(5482):1159-64.
2000: Matsuyama S; Llopis J; Deveraux Q L; Tsien R Y; Reed J C
Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis.
Nature cell biology 2000;2(6):318-25.
2000: Pawlowski K; Rychlewski L; Reed J C; Godzik A
From fold to function predictions: an apoptosis regulator protein BID.
Computers & chemistry 2000;24(3-4):511-7.
2000: Tamm I; Kornblau S M; Segall H; Krajewski S; Welsh K; Kitada S; Scudiero D A; Tudor G; Qui Y H; Monks A; Andreeff M; Reed J C
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1796-803.
2000: Jaroszewski L; Rychlewski L; Reed J C; Godzik A
ATP-activated oligomerization as a mechanism for apoptosis regulation: fold and mechanism prediction for CED-4.
Proteins 2000;39(3):197-203.
2000: Zapata J M; Matsuzawa S; Godzik A; Leo E; Wasserman S A; Reed J C
The Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFkappaB activity.
The Journal of biological chemistry 2000;275(16):12102-7.
2000: Zhang H; Xu Q; Krajewski S; Krajewska M; Xie Z; Fuess S; Kitada S; Pawlowski K; Godzik A; Reed J C
BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2597-602.
2000: Nouraini S; Six E; Matsuyama S; Krajewski S; Reed J C
The putative pore-forming domain of Bax regulates mitochondrial localization and interaction with Bcl-X(L).
Molecular and cellular biology 2000;20(5):1604-15.
2000: Wang X; Gjörloff-Wingren A; Saxena M; Pathan N; Reed J C; Mustelin T
The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):1934-9.
2000: Xu Q; Ke N; Matsuyama S; Reed J C
Assays for studying Bax-induced lethality in the yeast Saccharomyces cerevisiae.
Methods in enzymology 2000;322():283-96.
2000: Schendel S L; Reed J C
Measuring pore formation by Bcl-2 family proteins.
Methods in enzymology 2000;322():274-82.
2000: Xie Z; Reed J C
Analysis of dimerization of Bcl-2 family proteins by surface plasmon resonance.
Methods in enzymology 2000;322():266-74.
1999: Matsuyama S; Nouraini S; Reed J C
Yeast as a tool for apoptosis research.
Current opinion in microbiology 1999;2(6):618-23.
1999: Leo E; Zapata J M; Reed J C
CD40-mediated activation of Ig-Cgamma1- and Ig-cepsilon germ-line promoters involves multiple TRAF family proteins.
European journal of immunology 1999;29(12):3908-13.
1999: Deveraux Q L; Stennicke H R; Salvesen G S; Reed J C
Endogenous inhibitors of caspases.
Journal of clinical immunology 1999;19(6):388-98.
1999: Andreeff M; Jiang S; Zhang X; Konopleva M; Estrov Z; Snell V E; Xie Z; Okcu M F; Sanchez-Williams G; Dong J; Estey E H; Champlin R C; Kornblau S M; Reed J C; Zhao S
Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(11):1881-92.
1999: Torii S; Egan D A; Evans R A; Reed J C
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).
The EMBO journal 1999;18(21):6037-49.
1999: Ye X; Mehlen P; Rabizadeh S; VanArsdale T; Zhang H; Shin H; Wang J J; Leo E; Zapata J; Hauser C A; Reed J C; Bredesen D E
TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction.
The Journal of biological chemistry 1999;274(42):30202-8.
1999: Deveraux Q L; Leo E; Stennicke H R; Welsh K; Salvesen G S; Reed J C
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases.
The EMBO journal 1999;18(19):5242-51.
1999: Kitada S; Zapata J M; Andreeff M; Reed J C
Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia.
British journal of haematology 1999;106(4):995-1004.
1999: Leo E; Welsh K; Matsuzawa S; Zapata J M; Kitada S; Mitchell R S; Ely K R; Reed J C
Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kappaB and Jun N-terminal kinase activation.
The Journal of biological chemistry 1999;274(32):22414-22.
1999: Schendel S L; Azimov R; Pawlowski K; Godzik A; Kagan B L; Reed J C
Ion channel activity of the BH3 only Bcl-2 family member, BID.
The Journal of biological chemistry 1999;274(31):21932-6.
1999: Reed J C; Paternostro G
Postmitochondrial regulation of apoptosis during heart failure.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):7614-6.
1999: Krajewski S; Krajewska M; Ellerby L M; Welsh K; Xie Z; Deveraux Q L; Salvesen G S; Bredesen D E; Rosenthal R E; Fiskum G; Reed J C
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5752-7.
1999: Gil J; Yamamoto H; Zapata J M; Reed J C; Perucho M
Impairment of the proapoptotic activity of Bax by missense mutations found in gastrointestinal cancers.
Cancer research 1999;59(9):2034-7.
1999: Xu Q; Jürgensmeier J M; Reed J C
Methods of assaying Bcl-2 and Bax family proteins in yeast.
Methods (San Diego, Calif.) 1999;17(4):292-304.
1999: Wang H G; Pathan N; Ethell I M; Krajewski S; Yamaguchi Y; Shibasaki F; McKeon F; Bobo T; Franke T F; Reed J C
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD.
Science (New York, N.Y.) 1999;284(5412):339-43.
1999: Krajewski S; Krajewska M; Turner B C; Pratt C; Howard B; Zapata J M; Frenkel V; Robertson S; Ionov Y; Yamamoto H; Perucho M; Takayama S; Reed J C
Prognostic significance of apoptosis regulators in breast cancer.
Endocrine-related cancer 1999;6(1):29-40.
1999: Stennicke H R; Deveraux Q L; Humke E W; Reed J C; Dixit V M; Salvesen G S
Caspase-9 can be activated without proteolytic processing.
The Journal of biological chemistry 1999;274(13):8359-62.
1999: Froesch B A; Aimé-Sempé C; Leber B; Andrews D; Reed J C
Inhibition of p53 transcriptional activity by Bcl-2 requires its membrane-anchoring domain.
The Journal of biological chemistry 1999;274(10):6469-75.
1999: Deveraux Q L; Reed J C
IAP family proteins--suppressors of apoptosis.
Genes & development 1999;13(3):239-52.
1999: Slee E A; Harte M T; Kluck R M; Wolf B B; Casiano C A; Newmeyer D D; Wang H G; Reed J C; Nicholson D W; Alnemri E S; Green D R; Martin S J
Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner.
The Journal of cell biology 1999;144(2):281-92.
1999: Takayama S; Xie Z; Reed J C
An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.
The Journal of biological chemistry 1999;274(2):781-6.
1998: Reed J C
Bcl-2 family proteins.
Oncogene 1998;17(25):3225-36.
1998: Tamm I; Wang Y; Sausville E; Scudiero D A; Vigna N; Oltersdorf T; Reed J C
IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.
Cancer research 1998;58(23):5315-20.
1998: Bimston D; Song J; Winchester D; Takayama S; Reed J C; Morimoto R I
BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release.
The EMBO journal 1998;17(23):6871-8.
1998: Matsuyama S; Schendel S L; Xie Z; Reed J C
Cytoprotection by Bcl-2 requires the pore-forming alpha5 and alpha6 helices.
The Journal of biological chemistry 1998;273(47):30995-1001.
1998: Cardone M H; Roy N; Stennicke H R; Salvesen G S; Franke T F; Stanbridge E; Frisch S; Reed J C
Regulation of cell death protease caspase-9 by phosphorylation.
Science (New York, N.Y.) 1998;282(5392):1318-21.
1998: Stennicke H R; Jürgensmeier J M; Shin H; Deveraux Q; Wolf B B; Yang X; Zhou Q; Ellerby H M; Ellerby L M; Bredesen D; Green D R; Reed J C; Froelich C J; Salvesen G S
Pro-caspase-3 is a major physiologic target of caspase-8.
The Journal of biological chemistry 1998;273(42):27084-90.
1998: Reed J C; Jurgensmeier J M; Matsuyama S
Bcl-2 family proteins and mitochondria.
Biochimica et biophysica acta 1998;1366(1-2):127-37.
1998: Stuart J K; Myszka D G; Joss L; Mitchell R S; McDonald S M; Xie Z; Takayama S; Reed J C; Ely K R
Characterization of interactions between the anti-apoptotic protein BAG-1 and Hsc70 molecular chaperones.
The Journal of biological chemistry 1998;273(35):22506-14.
1998: Li Y; Lin B; Agadir A; Liu R; Dawson M I; Reed J C; Fontana J A; Bost F; Hobbs P D; Zheng Y; Chen G Q; Shroot B; Mercola D; Zhang X K
Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines.
Molecular and cellular biology 1998;18(8):4719-31.
1998: Kobayashi T; Ruan S; Jabbur J R; Consoli U; Clodi K; Shiku H; Owen-Schaub L B; Andreeff M; Reed J C; Zhang W
Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment.
Cell death and differentiation 1998;5(7):584-91.
1998: Reed J C
Molecular biology of chronic lymphocytic leukemia: implications for therapy.
Seminars in hematology 1998;35(3 Suppl 3):3-13.
1998: Takayama S; Krajewski S; Krajewska M; Kitada S; Zapata J M; Kochel K; Knee D; Scudiero D; Tudor G; Miller G J; Miyashita T; Yamada M; Reed J C
Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines.
Cancer research 1998;58(14):3116-31.
1998: Liu R; Takayama S; Zheng Y; Froesch B; Chen G Q; Zhang X; Reed J C; Zhang X K
Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells.
The Journal of biological chemistry 1998;273(27):16985-92.
1998: Krajewska M; Krajewski S; Zapata J M; Van Arsdale T; Gascoyne R D; Berern K; McFadden D; Shabaik A; Hugh J; Reynolds A; Clevenger C V; Reed J C
TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues.
The American journal of pathology 1998;152(6):1549-61.
1998: Krajewski S; Hugger A; Krajewska M; Reed J C; Mai J K
Developmental expression patterns of Bcl-2, Bcl-x, Bax, and Bak in teeth.
Cell death and differentiation 1998;5(5):408-15.
1998: Schendel S L; Montal M; Reed J C
Bcl-2 family proteins as ion-channels.
Cell death and differentiation 1998;5(5):372-80.
1998: Matsuzawa S; Takayama S; Froesch B A; Zapata J M; Reed J C
p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1.
The EMBO journal 1998;17(10):2736-47.
1998: Xie Z; Schendel S; Matsuyama S; Reed J C
Acidic pH promotes dimerization of Bcl-2 family proteins.
Biochemistry 1998;37(18):6410-8.
1998: Froesch B A; Takayama S; Reed J C
BAG-1L protein enhances androgen receptor function.
The Journal of biological chemistry 1998;273(19):11660-6.
1998: Kitada S; Andersen J; Akar S; Zapata J M; Takayama S; Krajewski S; Wang H G; Zhang X; Bullrich F; Croce C M; Rai K; Hines J; Reed J C
Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses.
Blood 1998;91(9):3379-89.
1998: Jürgensmeier J M; Xie Z; Deveraux Q; Ellerby L; Bredesen D; Reed J C
Bax directly induces release of cytochrome c from isolated mitochondria.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(9):4997-5002.
1998: Deveraux Q L; Roy N; Stennicke H R; Van Arsdale T; Zhou Q; Srinivasula S M; Alnemri E S; Salvesen G S; Reed J C
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases.
The EMBO journal 1998;17(8):2215-23.
1998: Takahashi R; Deveraux Q; Tamm I; Welsh K; Assa-Munt N; Salvesen G S; Reed J C
A single BIR domain of XIAP sufficient for inhibiting caspases.
The Journal of biological chemistry 1998;273(14):7787-90.
1998: Reed J C
Molecular biology of chronic lymphocytic leukemia.
Seminars in oncology 1998;25(1):11-8.
1998: Kitada S; Krajewska M; Zhang X; Scudiero D; Zapata J M; Wang H G; Shabaik A; Tudor G; Krajewski S; Myers T G; Johnson G S; Sausville E A; Reed J C
Expression and location of pro-apoptotic Bcl-2 family protein BAD in normal human tissues and tumor cell lines.
The American journal of pathology 1998;152(1):51-61.
1997: Krajewski S; Zapata J M; Krajewska M; VanArsdale T; Shabaik A; Gascoyne R D; Reed J C
Immunohistochemical analysis of in vivo patterns of TRAF-3 expression, a member of the TNF receptor-associated factor family.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):5841-52.
1997: Zha H; Reed J C
Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells.
The Journal of biological chemistry 1997;272(50):31482-8.
1997: Roy N; Deveraux Q L; Takahashi R; Salvesen G S; Reed J C
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases.
The EMBO journal 1997;16(23):6914-25.
1997: Reed J C
Cytochrome c: can't live with it--can't live without it.
Cell 1997;91(5):559-62.
1997: Reed J C
Bcl-2 family proteins: regulators of apoptosis and chemoresistance in hematologic malignancies.
Seminars in hematology 1997;34(4 Suppl 5):9-19.
1997: Vachon P H; Xu H; Liu L; Loechel F; Hayashi Y; Arahata K; Reed J C; Wewer U M; Engvall E
Integrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy.
The Journal of clinical investigation 1997;100(7):1870-81.
1997: Takayama S; Bimston D N; Matsuzawa S; Freeman B C; Aime-Sempe C; Xie Z; Morimoto R I; Reed J C
BAG-1 modulates the chaperone activity of Hsp70/Hsc70.
The EMBO journal 1997;16(16):4887-96.
1997: Deveraux Q L; Takahashi R; Salvesen G S; Reed J C
X-linked IAP is a direct inhibitor of cell-death proteases.
Nature 1997;388(6639):300-4.
1997: Krajewski S; Gascoyne R D; Zapata J M; Krajewska M; Kitada S; Chhanabhai M; Horsman D; Berean K; Piro L D; Fugier-Vivier I; Liu Y J; Wang H G; Reed J C
Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.
Blood 1997;89(10):3817-25.
1997: Schendel S L; Xie Z; Montal M O; Matsuyama S; Montal M; Reed J C
Channel formation by antiapoptotic protein Bcl-2.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5113-8.
1997: Reed J C; Orrenius S; Slater A F
4th IUBMB conference on 'The Life and Death of the Cell'. Edinburgh 14-17th July 1996.
Cell death and differentiation 1997;4(3):254-8.
1997: Keane R W; Srinivasan A; Foster L M; Testa M P; Ord T; Nonner D; Wang H G; Reed J C; Bredesen D E; Kayalar C
Activation of CPP32 during apoptosis of neurons and astrocytes.
Journal of neuroscience research 1997;48(2):168-80.
1997: Krajewska M; Wang H G; Krajewski S; Zapata J M; Shabaik A; Gascoyne R; Reed J C
Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease.
Cancer research 1997;57(8):1605-13.
1997: Krajewski S; Krajewska M; Ehrmann J; Sikorska M; Lach B; Chatten J; Reed J C
Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin.
The American journal of pathology 1997;150(3):805-14.
1997: Krajewski S; Thor A D; Edgerton S M; Moore D H; Krajewska M; Reed J C
Analysis of Bax and Bcl-2 expression in p53-immunopositive breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(2):199-208.
1997: Rampino N; Yamamoto H; Ionov Y; Li Y; Sawai H; Reed J C; Perucho M
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.
Science (New York, N.Y.) 1997;275(5302):967-9.
1997: Reed J C
Bcl-2 family proteins and the hormonal control of cell life and death in normalcy and neoplasia.
Vitamins and hormones 1997;53():99-138.
1996: Wang H G; Rapp U R; Reed J C
Bcl-2 targets the protein kinase Raf-1 to mitochondria.
Cell 1996;87(4):629-38.
1996: Krajewska M; Fenoglio-Preiser C M; Krajewski S; Song K; Macdonald J S; Stemmerman G; Reed J C
Immunohistochemical analysis of Bcl-2 family proteins in adenocarcinomas of the stomach.
The American journal of pathology 1996;149(5):1449-57.
1996: Zha H; Fisk H A; Yaffe M P; Mahajan N; Herman B; Reed J C
Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells.
Molecular and cellular biology 1996;16(11):6494-508.
1996: Reed J C
Mechanisms of Bcl-2 family protein function and dysfunction in health and disease.
Behring Institute Mitteilungen 1996;(97):72-100.
1996: Wang H G; Takayama S; Rapp U R; Reed J C
Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7063-8.
1996: Krajewski S; Krajewska M; Reed J C
Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family.
Cancer research 1996;56(12):2849-55.
1996: Krajewski S; Zapata J M; Reed J C
Detection of multiple antigens on western blots.
Analytical biochemistry 1996;236(2):221-8.
1996: Krajewska M; Moss S F; Krajewski S; Song K; Holt P R; Reed J C
Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas.
Cancer research 1996;56(10):2422-7.
1996: Krajewska M; Krajewski S; Epstein J I; Shabaik A; Sauvageot J; Song K; Kitada S; Reed J C
Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers.
The American journal of pathology 1996;148(5):1567-76.
1996: Zhang Z; Vuori K; Wang H; Reed J C; Ruoslahti E
Integrin activation by R-ras.
Cell 1996;85(1):61-9.
1996: Harigai M; Miyashita T; Hanada M; Reed J C
A cis-acting element in the BCL-2 gene controls expression through translational mechanisms.
Oncogene 1996;12(6):1369-74.
1996: Zha H; Aimé-Sempé C; Sato T; Reed J C
Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2.
The Journal of biological chemistry 1996;271(13):7440-4.
1996: Liu Y; Lee M O; Wang H G; Li Y; Hashimoto Y; Klaus M; Reed J C; Zhang X
Retinoic acid receptor beta mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells.
Molecular and cellular biology 1996;16(3):1138-49.
1996: Reed J C; Miyashita T; Takayama S; Wang H G; Sato T; Krajewski S; Aimé-Sempé C; Bodrug S; Kitada S; Hanada M
BCL-2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy.
Journal of cellular biochemistry 1996;60(1):23-32.
1996: Kitada S; Krajewski S; Miyashita T; Krajewska M; Reed J C
Gamma-radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo.
Oncogene 1996;12(1):187-92.
1996: Reed J C; Zha H; Aime-Sempe C; Takayama S; Wang H G
Structure-function analysis of Bcl-2 family proteins. Regulators of programmed cell death.
Advances in experimental medicine and biology 1996;406():99-112.
1996: Reed J C; Miyashita T; Krajewski S; Takayama S; Aime-Sempe C; Kitada S; Sato T; Wang H G; Harigai M; Hanada M; Krajewska M; Kochel K; Millan J; Kobayashi H
Bcl-2 family proteins and the regulation of programmed cell death in leukemia and lymphoma.
Cancer treatment and research 1996;84():31-72.
1995: Miyashita T; Kitada S; Krajewski S; Horne W A; Delia D; Reed J C
Overexpression of the Bcl-2 protein increases the half-life of p21Bax.
The Journal of biological chemistry 1995;270(44):26049-52.
1995: Martin S J; Newmeyer D D; Mathias S; Farschon D M; Wang H G; Reed J C; Kolesnick R N; Green D R
Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis.
The EMBO journal 1995;14(21):5191-200.
1995: Krajewski S; Blomqvist C; Franssila K; Krajewska M; Wasenius V M; Niskanen E; Nordling S; Reed J C
Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma.
Cancer research 1995;55(19):4471-8.
1995: Krajewski S; Mai J K; Krajewska M; Sikorska M; Mossakowski M J; Reed J C
Upregulation of bax protein levels in neurons following cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(10):6364-76.
1995: Krajewski S; Bodrug S; Krajewska M; Shabaik A; Gascoyne R; Berean K; Reed J C
Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo.
The American journal of pathology 1995;146(6):1309-19.
1995: Wang H G; Millan J A; Cox A D; Der C J; Rapp U R; Beck T; Zha H; Reed J C
R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.
The Journal of cell biology 1995;129(4):1103-14.
1995: Hanada M; Aimé-Sempé C; Sato T; Reed J C
Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax.
The Journal of biological chemistry 1995;270(20):11962-9.
1995: Reed J C
Bcl-2: prevention of apoptosis as a mechanism of drug resistance.
Hematology/oncology clinics of North America 1995;9(2):451-73.
1995: Sato T; Irie S; Kitada S; Reed J C
FAP-1: a protein tyrosine phosphatase that associates with Fas.
Science (New York, N.Y.) 1995;268(5209):411-5.
1995: Tron V A; Krajewski S; Klein-Parker H; Li G; Ho V C; Reed J C
Immunohistochemical analysis of Bcl-2 protein regulation in cutaneous melanoma.
The American journal of pathology 1995;146(3):643-50.
1995: Krajewski S; Chatten J; Hanada M; Reed J C
Immunohistochemical analysis of the Bcl-2 oncoprotein in human neuroblastomas. Comparisons with tumor cell differentiation and N-Myc protein.
Laboratory investigation; a journal of technical methods and pathology 1995;72(1):42-54.
1995: Miyashita T; Reed J C
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene.
Cell 1995;80(2):293-9.
1995: Takayama S; Sato T; Krajewski S; Kochel K; Irie S; Millan J A; Reed J C
Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity.
Cell 1995;80(2):279-84.
1995: Sato T; Irie S; Reed J C
A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40.
FEBS letters 1995;358(2):113-8.
1994: Krajewski S; Krajewska M; Shabaik A; Miyashita T; Wang H G; Reed J C
Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.
The American journal of pathology 1994;145(6):1323-36.
1994: Krajewski S; Krajewska M; Shabaik A; Wang H G; Irie S; Fong L; Reed J C
Immunohistochemical analysis of in vivo patterns of Bcl-X expression.
Cancer research 1994;54(21):5501-7.
1994: Newmeyer D D; Farschon D M; Reed J C
Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria.
Cell 1994;79(2):353-64.
1994: Krajewski S; Bodrug S; Gascoyne R; Berean K; Krajewska M; Reed J C
Immunohistochemical analysis of Mcl-1 and Bcl-2 proteins in normal and neoplastic lymph nodes.
The American journal of pathology 1994;145(3):515-25.
1994: Torigoe T; Millan J A; Takayama S; Taichman R; Miyashita T; Reed J C
Bcl-2 inhibits T-cell-mediated cytolysis of a leukemia cell line.
Cancer research 1994;54(18):4851-4.
1994: Torigoe T; Millan J A; Chan K W; Taichman R; Brian A A; Reed J C; Tachman R [corrected to Taichman R ]
Protein tyrosine kinase p56-Lck regulates lymphocyte function-associated 1 adhesion molecule expression, granule exocytosis, and cytolytic effector function in a cloned T cell.
The Journal of experimental medicine 1994;180(3):1115-27.
1994: Selvakumaran M; Reed J C; Liebermann D; Hoffman B
Progression of the myeloid differentiation program is dominant to transforming growth factor-beta 1-induced apoptosis in M1 myeloid leukemic cells.
Blood 1994;84(4):1036-42.
1994: Miyashita T; Harigai M; Hanada M; Reed J C
Identification of a p53-dependent negative response element in the bcl-2 gene.
Cancer research 1994;54(12):3131-5.
1994: Miyashita T; Krajewski S; Krajewska M; Wang H G; Lin H K; Liebermann D A; Hoffman B; Reed J C
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.
Oncogene 1994;9(6):1799-805.
1994: Selvakumaran M; Lin H K; Miyashita T; Wang H G; Krajewski S; Reed J C; Hoffman B; Liebermann D
Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways.
Oncogene 1994;9(6):1791-8.
1994: Sakuragi N; Matsuo H; Coukos G; Furth E E; Bronner M P; VanArsdale C M; Krajewsky S; Reed J C; Strauss J F
Differentiation-dependent expression of the BCL-2 proto-oncogene in the human trophoblast lineage.
Journal of the Society for Gynecologic Investigation 1994;1(2):164-72.
1994: Selvakumaran M; Lin H K; Sjin R T; Reed J C; Liebermann D A; Hoffman B
The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells.
Molecular and cellular biology 1994;14(4):2352-60.
1994: Clevenger C V; Torigoe T; Reed J C
Prolactin induces rapid phosphorylation and activation of prolactin receptor-associated RAF-1 kinase in a T-cell line.
The Journal of biological chemistry 1994;269(8):5559-65.
1994: Reed J C
Bcl-2 and the regulation of programmed cell death.
The Journal of cell biology 1994;124(1-2):1-6.
1994: Reed J C; Kitada S; Takayama S; Miyashita T
Regulation of chemoresistance by the bcl-2 oncoprotein in non-Hodgkin's lymphoma and lymphocytic leukemia cell lines.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5 Suppl 1():61-5.
1994: Kitada S; Takayama S; De Riel K; Tanaka S; Reed J C
Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression.
Antisense research and development 1994;4(2):71-9.
1993: Hanada M; Krajewski S; Tanaka S; Cazals-Hatem D; Spengler B A; Ross R A; Biedler J L; Reed J C
Regulation of Bcl-2 oncoprotein levels with differentiation of human neuroblastoma cells.
Cancer research 1993;53(20):4978-86.
1993: Reed J C; Torigoe T; Turner B C; Merida I; Gaulton G; Saragovi H U; Rapp U R; Taichman R
Protooncogene-encoded protein kinases in interleukin-2 signal transduction.
Seminars in immunology 1993;5(5):327-36.
1993: Taichman R; Merida I; Torigoe T; Gaulton G N; Reed J C
Evidence that protein tyrosine kinase p56-Lck regulates the activity of phosphatidylinositol-3'-kinase in interleukin-2-dependent T-cells.
The Journal of biological chemistry 1993;268(27):20031-6.
1993: Reed J C; Tanaka S
Somatic point mutations in the translocated bcl-2 genes of non-Hodgkin's lymphomas and lymphocytic leukemias: implications for mechanisms of tumor progression.
Leukemia & lymphoma 1993;10(3):157-63.
1993: Turner B C; Tonks N K; Rapp U R; Reed J C
Interleukin 2 regulates Raf-1 kinase activity through a tyrosine phosphorylation-dependent mechanism in a T-cell line.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5544-8.
1993: Tanaka S; Saito K; Reed J C
Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival.
The Journal of biological chemistry 1993;268(15):10920-6.
1993: Baffy G; Miyashita T; Williamson J R; Reed J C
Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production.
The Journal of biological chemistry 1993;268(9):6511-9.
1993: Taichman R S; Torigoe T; Reed J C
A strategy for constructing inducible expression plasmids for T-lymphocytes.
BioTechniques 1993;14(2):180-2.
1993: Miyashita T; Reed J C
Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line.
Blood 1993;81(1):151-7.
1993: Kitada S; Miyashita T; Tanaka S; Reed J C
Investigations of antisense oligonucleotides targeted against bcl-2 RNAs.
Antisense research and development 1993;3(2):157-69.
1992: Katsumata M; Siegel R M; Louie D C; Miyashita T; Tsujimoto Y; Nowell P C; Greene M I; Reed J C
Differential effects of Bcl-2 on T and B cells in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11376-80.
1992: Quill H; Riley M P; Cho E A; Casnellie J E; Reed J C; Torigoe T
Anergic Th1 cells express altered levels of the protein tyrosine kinases p56lck and p59fyn.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(9):2887-93.
1992: Taichman R S; Torigoe T; Tanaka S; Miyashita T; Reed J C
Gene transfer investigations of p56-LCK function in IL-2-dependent T-cell lines: implications for mechanisms of IL-2-signal transduction.
Cytokine 1992;4(6):441-53.
1992: Reed J C; Miyashita T; Cuddy M; Cho D
Regulation of p26-bcl-2 protein levels in human peripheral blood lymphocytes.
Laboratory investigation; a journal of technical methods and pathology 1992;67(4):443-9.
1992: Miyashita T; Reed J C
bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs.
Cancer research 1992;52(19):5407-11.
1992: Torigoe T; O'Connor R; Fagard R; Fischer S; Santoli D; Reed J C
Interleukin 4 inhibits IL-2-induced proliferation of a human T-leukemia cell line without interfering with p56-LCK kinase activation.
Cytokine 1992;4(5):369-76.
1992: Torigoe T; O'Connor R; Santoli D; Reed J C
Interleukin-3 regulates the activity of the LYN protein-tyrosine kinase in myeloid-committed leukemic cell lines.
Blood 1992;80(3):617-24.
1992: Cazals-Hatem D L; Louie D C; Tanaka S; Reed J C
Molecular cloning and DNA sequence analysis of cDNA encoding chicken homologue of the Bcl-2 oncoprotein.
Biochimica et biophysica acta 1992;1132(1):109-13.
1992: Siegel R M; Katsumata M; Miyashita T; Louie D C; Greene M I; Reed J C
Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7003-7.
1992: Reed J C; Tanaka S; Cuddy M; Cho D; Smith J; Kallen R; Saragovi H U; Torigoe T
A strategy for generating monoclonal antibodies against recombinant baculovirus-produced proteins: application to the Bcl-2 oncoprotein.
Analytical biochemistry 1992;205(1):70-6.
1992: Reed J C; Tanaka S; Cuddy M
Cell cycle analysis of p26-BCL-2 protein levels in proliferating lymphoma and leukemia cell lines.
Cancer research 1992;52(10):2802-5.
1992: Torigoe T; Saragovi H U; Reed J C
Interleukin 2 regulates the activity of the lyn protein-tyrosine kinase in a B-cell line.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2674-8.
1992: Tanaka S; Louie D C; Kant J A; Reed J C
Frequent incidence of somatic mutations in translocated BCL2 oncogenes of non-Hodgkin's lymphomas.
Blood 1992;79(1):229-37.
1992: Torigoe T; O-Connor R; Fagard R; Fischer S; Santoli D; Reed J C
Regulation of SRC-family protein tyrosine kinases by interleukins, IL-2, and IL-3.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6 Suppl 3():94S-97S.
1992: Tanaka S; Louie D; Kant J; Reed J C
Application of a PCR-mismatch technique to the BCL-2 gene: detection of point mutations in BCL-2 genes of malignancies with A t(14,18).
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6 Suppl 3():15S-19S.
1991: Louie D C; Kant J A; Brooks J J; Reed J C
Absence of t(14;18) major and minor breakpoints and of Bcl-2 protein overproduction in Reed-Sternberg cells of Hodgkin's disease.
The American journal of pathology 1991;139(6):1231-7.
1991: Reed J C; Meister L; Tanaka S; Cuddy M; Yum S; Geyer C; Pleasure D
Differential expression of bcl2 protooncogene in neuroblastoma and other human tumor cell lines of neural origin.
Cancer research 1991;51(24):6529-38.
1991: Geyer C K; Zhu X; Nowell P C; Reed J C
A new polymorphic probe on chromosome 6q: p327A (D6S93).
Nucleic acids research 1991;19(20):5799.
1991: Reed J C; Talwar H S; Cuddy M; Baffy G; Williamson J; Rapp U R; Fisher G J
Mitochondrial protein p26 BCL2 reduces growth factor requirements of NIH3T3 fibroblasts.
Experimental cell research 1991;195(2):277-83.
1991: Reed J C; Yum S; Cuddy M P; Turner B C; Rapp U R
Differential regulation of the p72-74 RAF-1 kinase in 3T3 fibroblasts expressing ras or src oncogenes.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(5):235-43.
1991: Tanaka S; Kant J; Reed J C
G to A polymorphism in the second exon of the BCL2 gene.
Nucleic acids research 1991;19(8):1964.
1991: Makni H; Malter J S; Reed J C; Nobuhiko S; Lang G; Kioussis D; Trinchieri G; Kamoun M
Reconstitution of an active surface CD2 by DNA transfer in CD2-CD3+ Jurkat cells facilitates CD3-T cell receptor-mediated IL-2 production.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(8):2522-9.
1991: Makover D; Cuddy M; Yum S; Bradley K; Alpers J; Sukhatme V; Reed J C
Phorbol ester-mediated inhibition of growth and regulation of proto-oncogene expression in the human T cell leukemia line JURKAT.
Oncogene 1991;6(3):455-60.
1991: Reed J C; Rapp U; Cuddy M P
Transformed 3T3 cells have reduced levels and altered subcellular distribution of the major PKC substrate protein MARCKS.
Cellular signalling 1991;3(6):569-76.
1990: Haldar S; Reed J C; Beatty C; Croce C M
Role of bcl-2 in growth factor triggered signal transduction.
Cancer research 1990;50(22):7399-401.
1990: Reed J C; Stein C; Subasinghe C; Haldar S; Croce C M; Yum S; Cohen J
Antisense-mediated inhibition of BCL2 protooncogene expression and leukemic cell growth and survival: comparisons of phosphodiester and phosphorothioate oligodeoxynucleotides.
Cancer research 1990;50(20):6565-70.
1990: Reed J C; Haldar S; Croce C M; Cuddy M P
Complementation by BCL2 and C-HA-RAS oncogenes in malignant transformation of rat embryo fibroblasts.
Molecular and cellular biology 1990;10(8):4370-4.
1990: Reed J C; Cuddy M; Haldar S; Croce C; Nowell P; Makover D; Bradley K
BCL2-mediated tumorigenicity of a human T-lymphoid cell line: synergy with MYC and inhibition by BCL2 antisense.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3660-4.
1989: Reed J C; Haldar S; Cuddy M P; Croce C; Makover D
Deregulated BCL2 expression enhances growth of a human B cell line.
Oncogene 1989;4(9):1123-7.
1989: Reed J C; Tsujimoto Y; Epstein S F; Cuddy M; Slabiak T; Nowell P C; Croce C M
Regulation of bcl-2 gene expression in lymphoid cell lines containing normal #18 or t(14;18) chromosomes.
Oncogene research 1989;4(4):271-82.
1988: Reed J C; Cuddy M; Slabiak T; Croce C M; Nowell P C
Oncogenic potential of bcl-2 demonstrated by gene transfer.
Nature 1988;336(6196):259-61.
1988: Reed J C; Prystowsky M B; Nowell P C
Regulation of gene expression in lectin-stimulated or lymphokine-stimulated T lymphocytes. Effects of cyclosporine.
Transplantation 1988;46(2 Suppl):85S-89S.
1988: Malter J S; Reed J C; Kamoun M
Induction and regulation of CD2 mRNA in human lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(9):3233-6.
1988: Reed J C; Nowell P C
Soluble inhibitors of T lymphocyte proliferation: tools for dissecting pathways of T cell activation.
Immunologic research 1988;7(2):93-112.
1987: Broome H E; Reed J C; Godillot E P; Hoover R G
Differential promoter utilization by the c-myc gene in mitogen- and interleukin-2-stimulated human lymphocytes.
Molecular and cellular biology 1987;7(8):2988-93.
1987: Reed J C; Alpers J D; Scherle P A; Hoover R G; Nowell P C; Prystowsky M B
Proto-oncogene expression in cloned T lymphocytes: mitogens and growth factors induce different patterns of expression.
Oncogene 1987;1(2):223-8.
1987: Reed J C; Prystowsky M B; Kern J A; Alpers J D; Nowell P C; Hoover R G
Regulation of proto-oncogene expression during T lymphocyte activation and proliferation.
Advances in experimental medicine and biology 1987;213():249-62.
1986: Reed J C; Abidi A H; Alpers J D; Hoover R G; Robb R J; Nowell P C
Effect of cyclosporin A and dexamethasone on interleukin 2 receptor gene expression.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(1):150-4.
1986: Reed J C; Alpers J D; Nowell P C; Hoover R G
Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(11):3982-6.
1985: Reed J C; Sabath D E; Hoover R G; Prystowsky M B
Recombinant interleukin 2 regulates levels of c-myc mRNA in a cloned murine T lymphocyte.
Molecular and cellular biology 1985;5(12):3361-8.

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