Bernard Rees-Smith

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Núñez Miguel R; Sanders J; Chirgadze D Y; Furmaniak J; Rees Smith B
Thyroid stimulating autoantibody M22 mimics TSH binding to the TSH receptor leucine rich domain: a comparative structural study of protein-protein interactions.
Núñez Miguel R; Sanders J; Chirgadze D Y; Blundell T L; Furmaniak J; Rees Smith B
FSH and TSH binding to their respective receptors: similarities, differences and implication for glycoprotein hormone specificity.
Nilson Emma; Ekholm Birgitte; Rees Smith Bernard; Törn Carina; Hillman Magnus
Calcium addition to EDTA plasma eliminates falsely positive results in the RSR GADAb ELISA.

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2009: Núñez Miguel R; Sanders J; Chirgadze D Y; Furmaniak J; Rees Smith B
Thyroid stimulating autoantibody M22 mimics TSH binding to the TSH receptor leucine rich domain: a comparative structural study of protein-protein interactions.
Journal of molecular endocrinology 2009;42(5):381-95.
2008: Núñez Miguel R; Sanders J; Chirgadze D Y; Blundell T L; Furmaniak J; Rees Smith B
FSH and TSH binding to their respective receptors: similarities, differences and implication for glycoprotein hormone specificity.
Journal of molecular endocrinology 2008;41(3):145-64.
2008: Nilson Emma; Ekholm Birgitte; Rees Smith Bernard; Törn Carina; Hillman Magnus
Calcium addition to EDTA plasma eliminates falsely positive results in the RSR GADAb ELISA.
Clinica chimica acta; international journal of clinical chemistry 2008;388(1-2):130-4.
2006: Premawardhana L D K E; Wijeyaratne C N; Chen S; Wijesuriya M; Illangasekera U; Brooking H; Amoroso M; Jeffreys J; Bolton J; Lazarus J H; Furmaniak J; Rees Smith B
Islet cell, thyroid, adrenal and celiac disease related autoantibodies in patients with Type 1 diabetes from Sri Lanka.
Journal of endocrinological investigation 2006;29(11):968-74.
2006: Coco Graziella; Dal Pra Chiara; Presotto Fabio; Albergoni Maria Paola; Canova Cristina; Pedini Beniamino; Zanchetta Renato; Chen Shu; Furmaniak Jadwiga; Rees Smith Bernard; Mantero Franco; Betterle Corrado
Estimated risk for developing autoimmune Addison's disease in patients with adrenal cortex autoantibodies.
The Journal of clinical endocrinology and metabolism 2006;91(5):1637-45.
2006: Rees Smith B; Nordmeyer P; Sanders J; Furmaniak J
Eye signs of graves' disease and blocking-type thyrotropin receptor autoantibodies.
Thyroid : official journal of the American Thyroid Association 2006;16(1):97-8.
2005: Burne Peter; Mitchell Sarah; Rees Smith Bernard
Point-of-care assays for autoantibodies to thyroid peroxidase and to thyroglobulin.
Thyroid : official journal of the American Thyroid Association 2005;15(9):1005-10.
2004: Núñez Miguel Ricardo; Sanders Jane; Jeffreys Jennifer; Depraetere Hilde; Evans Michele; Richards Tonya; Blundell Tom L; Rees Smith Bernard; Furmaniak Jadwiga
Analysis of the thyrotropin receptor-thyrotropin interaction by comparative modeling.
Thyroid : official journal of the American Thyroid Association 2004;14(12):991-1011.
2004: Matthews Ian; Chen Shu; Hewer Rachel; McGrath Vivienne; Furmaniak Jadwiga; Rees Smith Bernard
Muscle-specific receptor tyrosine kinase autoantibodies--a new immunoprecipitation assay.
Clinica chimica acta; international journal of clinical chemistry 2004;348(1-2):95-9.
2004: Sanders J; Jeffreys J; Depraetere H; Evans M; Richards T; Kiddie A; Brereton K; Premawardhana L D K E; Chirgadze D Y; Núñez Miguel R; Blundell T L; Furmaniak J; Rees Smith B
Characteristics of a human monoclonal autoantibody to the thyrotropin receptor: sequence structure and function.
Thyroid : official journal of the American Thyroid Association 2004;14(8):560-70.
2004: Dal Pra Chiara; Chen Shu; Betterle Corrado; Zanchetta Renato; McGrath Vivienne; Furmaniak Jadwiga; Rees Smith Bernard
Autoantibodies to human tryptophan hydroxylase and aromatic L-amino acid decarboxylase.
European journal of endocrinology / European Federation of Endocrine Societies 2004;150(3):313-21.
2004: Nakachi Ken; Powell Michael; Swift Gillian; Amoroso Marie-Andrée; Ananieva-Jordanova Rossitza; Arnold Clare; Sanders Jane; Furmaniak Jadwiga; Rees Smith Bernard
Epitopes recognised by tissue transglutaminase antibodies in coeliac disease.
Journal of autoimmunity 2004;22(1):53-63.
2003: Miguel Ricardo Nunez; Sanders Jane; Jeffreys Jennifer; Depraetere Hilde; Blundell Tom; Furmaniak Jadwiga; Rees Smith Bernard
Thyrotropin receptor cleavage domain and tissue inhibitor of metalloproteinase-2.
Thyroid : official journal of the American Thyroid Association 2003;13(7):665-6.
2003: Sanders J; Evans M; Premawardhana L D K E; Depraetere H; Jeffreys J; Richards T; Furmaniak J; Rees Smith B
Human monoclonal thyroid stimulating autoantibody.
Lancet 2003;362(9378):126-8.
2002: Jeffreys Jennifer; Depraetere Hilde; Sanders Jane; Oda Yasuo; Evans Michele; Kiddie Angela; Richards Tonya; Furmaniak Jadwiga; Rees Smith Bernard
Characterization of the thyrotropin binding pocket.
Thyroid : official journal of the American Thyroid Association 2002;12(12):1051-61.
2002: Sanders Jane; Jeffreys Jennifer; Depraetere Hilde; Richards Tonya; Evans Michele; Kiddie Angela; Brereton Karen; Groenen Marleen; Oda Yasuo; Furmaniak Jadwiga; Rees Smith Bernard
Thyroid-stimulating monoclonal antibodies.
Thyroid : official journal of the American Thyroid Association 2002;12(12):1043-50.
2002: Phillips David I W; Osmond Clive; Baird Janis; Huckle Alison; Rees-Smith Bernard
Is birthweight associated with thyroid autoimmunity? A study in twins.
Thyroid : official journal of the American Thyroid Association 2002;12(5):377-80.
2001: Maruyama M; Sanders J; Oda Y; Kiddie A; Furmaniak J; Rees Smith B
Reactivity of thyrotropin receptor autoantibodies with the thyrotropin receptor on western blots.
Thyroid : official journal of the American Thyroid Association 2001;11(3):211-9.
2001: Nakachi K; Swift G; Wilmot D; Chapman C; Baker S; Powell M; Furmaniak J; Rees Smith B
Antibodies to tissue transglutaminase: comparison of ELISA and immunoprecipitation assay in the presence and in the absence of calcium ions.
Clinica chimica acta; international journal of clinical chemistry 2001;304(1-2):75-84.
2000: Gut P; Grennan Jones F; Sullivan A; Ziemnicka K; Smith S; Jaskólski D; Furmaniak J; Rees Smith B
Recombinant human thyroid peroxidase produced in insect cells has similar properties to native human thyroid peroxidase.
Thyroid : official journal of the American Thyroid Association 2000;10(7):543-50.
2000: Masuda M; Powell M; Chen S; Beer C; Fichna P; Rees Smith B; Furmaniak J
Autoantibodies to IA-2 in insulin-dependent diabetes mellitus. Measurements with a new immunoprecipitation assay.
Clinica chimica acta; international journal of clinical chemistry 2000;291(1):53-66.
1999: Bolton J; Sanders J; Oda Y; Chapman C; Konno R; Furmaniak J; Rees Smith B
Measurement of thyroid-stimulating hormone receptor autoantibodies by ELISA.
Clinical chemistry 1999;45(12):2285-7.
1999: Hendry E; Taylor G; Ziemnicka K; Grennan Jones F; Furmaniak J; Rees Smith B
Recombinant human thyroid peroxidase expressed in insect cells is soluble at high concentrations and forms diffracting crystals.
The Journal of endocrinology 1999;160(3):R13-5.
1999: Grennan Jones F; Ziemnicka K; Sanders J; Wolstenholme A; Fiera R; Furmaniak J; Rees Smith B
Analysis of autoantibody epitopes on human thyroid peroxidase.
Autoimmunity 1999;30(3):157-69.
1998: Oda Y; Sanders J; Roberts S; Maruyama M; Kato R; Perez M; Petersen V B; Wedlock N; Furmaniak J; Rees Smith B
Binding characteristics of antibodies to the TSH receptor.
Journal of molecular endocrinology 1998;20(2):233-44.
1998: Volpato M; Prentice L; Chen S; Betterle C; Rees Smith B; Furmaniak J
A study of the epitopes on steroid 21-hydroxylase recognized by autoantibodies in patients with or without Addison's disease.
Clinical and experimental immunology 1998;111(2):422-8.
1997: Betterle C; Volpato M; Rees Smith B; Furmaniak J; Chen S; Zanchetta R; Greggio N A; Pedini B; Boscaro M; Presotto F
II. Adrenal cortex and steroid 21-hydroxylase autoantibodies in children with organ-specific autoimmune diseases: markers of high progression to clinical Addison's disease.
The Journal of clinical endocrinology and metabolism 1997;82(3):939-42.
1997: Betterle C; Volpato M; Rees Smith B; Furmaniak J; Chen S; Greggio N A; Sanzari M; Tedesco F; Pedini B; Boscaro M; Presotto F
I. Adrenal cortex and steroid 21-hydroxylase autoantibodies in adult patients with organ-specific autoimmune diseases: markers of low progression to clinical Addison's disease.
The Journal of clinical endocrinology and metabolism 1997;82(3):932-8.
1996: Powell M; Prentice L; Asawa T; Kato R; Sawicka J; Tanaka H; Petersen V; Munkley A; Morgan S; Rees Smith B; Furmaniak J
Glutamic acid decarboxylase autoantibody assay using 125I-labelled recombinant GAD65 produced in yeast.
Clinica chimica acta; international journal of clinical chemistry 1996;256(2):175-88.
1996: Grennan Jones F; Wolstenholme A; Fowler S; Smith S; Ziemnicka K; Bradbury J; Furmaniak J; Rees Smith B
High-level expression of recombinant immunoreactive thyroid peroxidase in the High Five insect cell line.
Journal of molecular endocrinology 1996;17(2):165-74.
1996: Boscaro M; Betterle C; Volpato M; Fallo F; Furmaniak J; Rees Smith B; Sonino N
Hormonal responses during various phases of autoimmune adrenal failure: no evidence for 21-hydroxylase enzyme activity inhibition in vivo.
The Journal of clinical endocrinology and metabolism 1996;81(8):2801-4.
1996: Chen S; Sawicka J; Betterle C; Powell M; Prentice L; Volpato M; Rees Smith B; Furmaniak J
Autoantibodies to steroidogenic enzymes in autoimmune polyglandular syndrome, Addison's disease, and premature ovarian failure.
The Journal of clinical endocrinology and metabolism 1996;81(5):1871-6.
1995: Prentice L; Kiso Y; Fukuma N; Horimoto M; Petersen V; Grennan F; Pegg C; Furmaniak J; Rees Smith B
Monoclonal thyroglobulin autoantibodies: variable region analysis and epitope recognition.
The Journal of clinical endocrinology and metabolism 1995;80(3):977-86.
1994: Premawardhana L D; Lo S S; Phillips D I; Prentice L M; Rees Smith B
Variability of serum thyroglobulin levels is determined by a major gene.
Clinical endocrinology 1994;41(6):725-9.
1994: Asawa T; Wedlock N; Baumann-Antczak A; Rees Smith B; Furmaniak J
Adrenal autoantibodies and naturally occurring mutations in 21-hydroxylase.
Autoimmunity 1994;17(4):339-41.
1994: Hexham J M; Partridge L J; Furmaniak J; Petersen V B; Colls J C; Pegg C; Rees Smith B; Burton D R
Cloning and characterisation of TPO autoantibodies using combinatorial phage display libraries.
Autoimmunity 1994;17(3):167-79.
1993: Wedlock N; Furmaniak J; Fowler S; Kiso Y; Bednarek J; Baumann-Antczak A; Morteo C; Sudbery P; Hinchcliff A; Rees Smith B
Expression of human thyroid peroxidase in the yeasts Saccharomyces cerevisiae and Hansenula polymorpha.
Journal of molecular endocrinology 1993;10(3):325-36.
1993: Phillips D I; Cooper C; Fall C; Prentice L; Osmond C; Barker D J; Rees Smith B
Fetal growth and autoimmune thyroid disease.
The Quarterly journal of medicine 1993;86(4):247-53.
1993: Premawardhana L D; Kiso Y; Phillips D I; Morteo C; Furmaniak J; Rees Smith B
Is TPO detectable in the circulation?
Thyroid : official journal of the American Thyroid Association 1993;3(3):225-8.
1993: Prentice L; Phillips D I; Premawardhana L D; Rees Smith B
Genetic linkage analysis of thyroid autoantibodies.
Autoimmunity 1993;15(3):225-9.
1992: Bednarek J; Furmaniak J; Wedlock N; Kiso Y; Baumann-Antczak A; Fowler S; Krishnan H; Craft J A; Rees Smith B
Steroid 21-hydroxylase is a major autoantigen involved in adult onset autoimmune Addison's disease.
FEBS letters 1992;309(1):51-5.
1992: Hexham M; Pegg C; Burton D; Petersen V B; Horimoto M; Furmaniak J; Rees Smith B
Variable region sequence of a human monoclonal thyroid peroxidase autoantibody.
Autoimmunity 1992;14(2):169-72.
1992: Horimoto M; Petersen V S; Pegg C A; Fukuma N; Wakabayashi N; Kiso Y; Furmaniak J; Rees Smith B
Production and characterisation of a human monoclonal thyroid peroxidase autoantibody.
Autoimmunity 1992;14(1):1-7.
1991: Phillips D I; Prentice L; McLachlan S M; Upadhyaya M; Lunt P W; Rees Smith B
Autosomal dominant inheritance of the tendency of develop thyroid autoantibodies.
Experimental and clinical endocrinology 1991;97(2-3):170-2.
1991: Macht L; Fukuma N; Leader K; Sarsero D; Pegg C A; Phillips D I; Yates P; McLachlan S M; Elson C; Rees Smith B
Severe combined immunodeficient (SCID) mice: a model for investigating human thyroid autoantibody synthesis.
Clinical and experimental immunology 1991;84(1):34-42.
1991: Hexham J M; Persson M A; Pegg C; Burton D R; Furmaniak J; Rees Smith B
Cloning and expression of a human thyroglobulin autoantibody.
Autoimmunity 1991;11(1):69-70.
1991: Fukuma N; Petersen V B; McLachlan S M; Pegg C A; Rees Smith B
Human monoclonal thyroglobulin autoantibodies of high affinity. I. Production, characterisation and interaction with murine monoclonal thyroglobulin antibodies.
Autoimmunity 1991;10(4):291-5.
1991: Fukuma N F; McLachlan S M; Horimoto M; Petersen V B; Rees Smith B
Human monoclonal thyroglobulin autoantibodies of high affinity. II. Interaction between thyroglobulin and thyroglobulin autoantibodies of different IgG subclasses.
Autoimmunity 1991;11(2):97-105.
1990: Fukuma N; McLachlan S M; Rapoport B; Goodacre J; Middleton S L; Phillips D I; Pegg C A; Rees Smith B
Thyroid autoantigens and human T cell responses.
Clinical and experimental immunology 1990;82(2):275-83.
1990: McLachlan S M; Atherton M C; Nakajima Y; Napier J; Jordan R K; Clark F; Rees Smith B
Thyroid peroxidase and the induction of autoimmune thyroid disease.
Clinical and experimental immunology 1990;79(2):182-8.
1990: McLachlan S M; Taverne J; Atherton M C; Cooke A; Middleton S; Pegg C A; Clark F; Rees Smith B
Cytokines, thyroid autoantibody synthesis and thyroid cell survival in culture.
Clinical and experimental immunology 1990;79(2):175-81.
1990: Rees Smith B; Furmaniak J
Structural analysis of the TSH receptor.
Hormone and metabolic research. Supplement series 1990;23():28-32.
1988: Furmaniak J; Davenport S; Nakajima Y; Kaiser U; Muller-Gartner H W; Buckmann F W; Pegg C; Rees Smith B
Analysis of TSH receptors and microsomal antigen in different human thyroid tissue specimens.
Clinical endocrinology 1988;28(6):589-600.
1988: Nordmeyer J P; Hashim F A; Shafeh T; Eickenbusch W; Rees Smith B
TSH receptor antibodies in autoimmune thyroiditis.
Journal of clinical & laboratory immunology 1988;26(1):21-4.
1988: Furmaniak J; Talbot D; Reinwein D; Benker G; Creagh F M; Rees Smith B
Immunoprecipitation of human adrenal microsomal antigen.
FEBS letters 1988;231(1):25-8.
1988: Rees Smith B; McLachlan S M; Furmaniak J
Autoantibodies to the thyrotropin receptor.
Endocrine reviews 1988;9(1):106-21.
1987: Furmaniak J; Bradbury J; Rees Smith B
Antibodies to membrane antigens in autoimmune thyroid disease.
Acta endocrinologica 1987;116(1):13-20.
1987: McLachlan S M; Feldt-Rasmussen U; Young E T; Middleton S L; Dlichert-Toft M; Siersboek-Nielsen K; Date J; Carr D; Clark F; Rees Smith B
IgG subclass distribution of thyroid autoantibodies: a 'fingerprint' of an individual's response to thyroglobulin and thyroid microsomal antigen.
Clinical endocrinology 1987;26(3):335-46.
1987: Rees Smith B; Furmaniak J; Hashim F A; Jones E D; Howells R D; Nakajima Y
The subunit structure of the thyrotropin receptor.
Biochemical Society transactions 1987;15(1):51-5.
1987: Furmaniak J; Nakajima Y; Hashim F A; Creagh F M; Davies Jones E; Howells R D; McLachlan S M; Rees Smith B
The TSH receptor: structure and interaction with autoantibodies in thyroid disease.
Acta endocrinologica. Supplementum 1987;281():157-65.
1986: Hashim F A; Creagh F M; Hawrani A E; Parkes A B; Buckland P R; Rees Smith B
Characterization of TSH antagonist activity in the serum of patients with thyroid disease.
Clinical endocrinology 1986;25(3):275-81.
1986: McLachlan S M; Pegg C A; Atherton M C; Middleton S L; Dickinson A; Clark F; Proctor S J; Proud G; Rees Smith B
Subpopulations of thyroid autoantibody secreting lymphocytes in Graves' and Hashimoto thyroid glands.
Clinical and experimental immunology 1986;65(2):319-28.
1986: Wit J M; Rees-Smith B; Creagh F M; Bruinse H W; van der Heide D; Docter R; Gerards L J
Thyroid-stimulating immunoglobulins and thyroid function tests in two siblings with neonatal thyrotoxicosis.
European journal of pediatrics 1986;145(1-2):143-7.
1986: McLachlan S M; Atherton M C; Middleton S L; Clark F; Rees Smith B
A technique for the isolation and mitogenic activation of thyroglobulin-specific human B lymphocytes.
Immunology letters 1986;12(2-3):127-32.
1986: McLachlan S M; Pegg C A; Atherton M C; Middleton S L; Clark F; Rees Smith B
TSH receptor antibody synthesis by thyroid lymphocytes.
Clinical endocrinology 1986;24(2):223-30.
1986: McLachlan S M; Pegg C A; Atherton M C; Middleton S L; Clark F; Young E; Rees Smith B
In vitro studies of human thyroid autoantibody synthesis.
The Mount Sinai journal of medicine, New York 1986;53(1):38-45.
1986: Creagh F M; Howells R D; Williams S; Didcote S; Hashim F A; Petersen V B; Rees Smith B
IgG thyrotrophin receptor antibody activity in Graves' disease; a study of TSH agonist and antagonist activities by isoelectric focusing.
Clinical endocrinology 1986;24(1):79-88.
1986: Rees Smith B; Creagh F M; Hashim F A; Howells R D; Jones E D; Kajita Y; Buckland P R; Petersen V B
TSH receptor antibodies.
The Mount Sinai journal of medicine, New York 1986;53(1):53-9.
1985: Creagh F; Teece M; Williams S; Didcote S; Perkins W; Hashim F; Rees Smith B
An analysis of thyrotrophin receptor binding and thyroid stimulating activities in a series of Graves' sera.
Clinical endocrinology 1985;23(4):395-404.
1985: Phillips D I; Barker D J; Rees Smith B; Didcote S; Morgan D
The geographical distribution of thyrotoxicosis in England according to the presence or absence of TSH-receptor antibodies.
Clinical endocrinology 1985;23(3):283-7.
1985: Kajita Y; Morgan D; Parkes A B; Rees Smith B
Labelling and immunoprecipitation of thyroid microsomal antigen.
FEBS letters 1985;187(2):334-8.
1985: Creagh F M; Parkes A B; Tunn E; Ginsberg J; Hashim F; Rees Smith B
Thyroid stimulation by (Fab)2 and Fab fragments of TSH receptor antibody.
Clinical endocrinology 1985;23(2):175-83.
1985: Atherton M C; McLachlan S M; Pegg C A; Dickinson A; Baylis P; Young E T; Proctor S J; Rees Smith B
Thyroid autoantibody synthesis by lymphocytes from different lymphoid organs: fractionation of B cells on density gradients.
Immunology 1985;55(2):271-9.
1985: Davies Jones E; Hashim F A; Kajita Y; Creagh F M; Buckland P R; Petersen V B; Howells R D; Rees Smith B
Interaction of autoantibodies to thyrotropin receptor with a hydrophilic subunit of the thyrotropin receptor.
The Biochemical journal 1985;228(1):111-7.
1985: Rees Smith B; Rickards C R; Davies Jones E; Kajita Y; Buckland P R; Creagh F M; Howells R D; Hashim F; Parkes A B; Petersen V B
The thyrotropin receptor and its role in Graves' disease.
Journal of endocrinological investigation 1985;8(2):175-82.
1985: Kajita Y; Rickards C R; Buckland P R; Howells R D; Rees Smith B
Analysis of thyrotropin receptors by photoaffinity labelling. Orientation of receptor subunits in the cell membrane.
The Biochemical journal 1985;227(2):413-20.
1985: Parkes A B; Kajita Y; Buckland P R; Howells R D; Rickards C R; Creagh F M; Rees Smith B
Immunoprecipitation of TSH-TSH receptor complexes.
Clinical endocrinology 1985;22(4):511-20.
1985: McLachlan S M; Proud G; Pegg C A; Clark F; Rees Smith B
Functional analysis of T and B cells from blood and thyroid tissue in Hashimoto's disease.
Clinical and experimental immunology 1985;59(3):585-92.
1985: Buckland P R; Howells R D; Rickards C R; Rees Smith B
Affinity-labelling of the thyrotropin receptor. Characterization of the photoactive ligand.
The Biochemical journal 1985;225(3):753-60.
1985: Rees Smith B; Creagh F M; Hashim F A; Howells R D; Davies Jones E; Kajita Y; Buckland P R; Petersen V B
Thyrotropin receptor antibodies.
Arzneimittel-Forschung 1985;35(12A):1943-8.
1984: Parkes A B; McLachlan S M; Bird P; Rees Smith B
The distribution of microsomal and thyroglobulin antibody activity among the IgG subclasses.
Clinical and experimental immunology 1984;57(1):239-43.
1984: Southgate K; Creagh F; Teece M; Kingswood C; Rees Smith B
A receptor assay for the measurement of TSH receptor antibodies in unextracted serum.
Clinical endocrinology 1984;20(5):539-48.
1984: Buckland P R; Rees Smith B
A structural comparison of guinea pig thyroid and fat TSH receptors by photoaffinity labelling.
FEBS letters 1984;166(1):109-14.
1984: Davies Jones E; Rees Smith B
A water-soluble fragment of the thyroid-stimulating hormone receptor which binds both thyroid-stimulating hormone and thyroid-stimulating hormone receptor antibodies.
The Journal of endocrinology 1984;100(1):113-8.
1983: McLachlan S M; Dickinson A; Baylis P; Proctor S; Rees Smith B
Enrichment and depletion of thyroglobulin autoantibody synthesizing lymphocytes.
Clinical and experimental immunology 1983;53(2):397-405.

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