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Jane Reese

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Justin Roth; Giuliana Ferrari; Mourad Ismail; Karen T Lingas; Jane S Reese; Stanton L Gerson
Cotransduction with MGMT and Ubiquitous or Erythroid-Specific GFP Lentiviruses Allows Enrichment of Dual-Positive Hematopoietic Progenitor Cells In Vivo.
Jane S Reese; Justin Roth; Stanton L Gerson
Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance.
Steven P Zielske; Jane S Reese; Karen T Lingas; Jon R Donze; Stanton L Gerson
In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning.

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All Publications

2012: Justin Roth; Giuliana Ferrari; Mourad Ismail; Karen T Lingas; Jane S Reese; Stanton L Gerson
Cotransduction with MGMT and Ubiquitous or Erythroid-Specific GFP Lentiviruses Allows Enrichment of Dual-Positive Hematopoietic Progenitor Cells In Vivo.
ISRN hematology 2012;2012():212586.
2008: Jane S Reese; Justin Roth; Stanton L Gerson
Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance.
Stem cells (Dayton, Ohio) 2008;26(3):675-81.
2003: Steven P Zielske; Jane S Reese; Karen T Lingas; Jon R Donze; Stanton L Gerson
In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning.
The Journal of clinical investigation 2003;112(10):1561-70.
2003: Jane S Reese; Lili Liu; Stanton L Gerson
Repopulating defect of mismatch repair-deficient hematopoietic stem cells.
Blood 2003;102(5):1626-33.
2003: Brian M Davis; Jane S Reese; Karen T Lingas; Stanton L Gerson
Drug selection of mutant methylguanine methyltransferase from different oncoretroviral backbones results in multilineage hematopoietic transgene expression in primary and secondary recipients.
Journal of hematotherapy & stem cell research 2003;12(4):375-87.
2003: Janice E Bowman; Jane S Reese; Karen T Lingas; Stanton L Gerson
Myeloablation is not required to select and maintain expression of the drug-resistance gene, mutant MGMT, in primary and secondary recipients.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(1):42-50.
2003: J L Vollweiler; Steven P Zielske; Jane S Reese; Stanton L Gerson
Hematopoietic stem cell gene therapy: progress toward therapeutic targets.
Bone marrow transplantation 2003;32(1):1-7.
2001: Jane S Reese; E Allay; Stanton L Gerson
Overexpression of human O6-alkylguanine DNA alkyltransferase (AGT) prevents MNU induced lymphomas in heterozygous p53 deficient mice.
Oncogene 2001;20(38):5258-63.
2001: Jane S Reese; Xiusheng Qin; Christopher B Ballas; M Sekiguchi; Stanton L Gerson
MGMT expression in murine bone marrow is a major determinant of animal survival after alkylating agent exposure.
Journal of hematotherapy & stem cell research 2001;10(1):115-23.
1999: Jane S Reese; Omer N Koç; Stanton L Gerson
Human mesenchymal stem cells provide stromal support for efficient CD34+ transduction.
Journal of hematotherapy & stem cell research 1999;8(5):515-23.
1999: Omer N Koç; Jane S Reese; Emese Szekely; Stanton L Gerson
Human long-term culture initiating cells are sensitive to benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea and protected after mutant (G156A) methylguanine methyltransferase gene transfer.
Cancer gene therapy 1999;6(4):340-8.
1999: Omer N Koç; Jane S Reese; Brian M Davis; Lili Liu; K J Majczenko; Stanton L Gerson
DeltaMGMT-transduced bone marrow infusion increases tolerance to O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea and allows intensive therapy of 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human colon cancer xenografts.
Human gene therapy 1999;10(6):1021-30.
1999: Brian M Davis; Omer N Koç; Jane S Reese; Stanton L Gerson
O6-benzylguanine-resistant mutant MGMT genes improve hematopoietic cell tolerance to alkylating agents.
Progress in experimental tumor research 1999;36():65-81.
1999: Jane S Reese; Brian M Davis; Lili Liu; Stanton L Gerson
Simultaneous protection of G156A methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and sensitization of tumor cells using O6-benzylguanine and temozolomide.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):163-9.
1997: Brian M Davis; Jane S Reese; Omer N Koç; K Lee; Jane E Schupp; Stanton L Gerson
Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Cancer research 1997;57(22):5093-9.
1997: E Allay; Jane S Reese; E A McGuire; Omer N Koç; N Sedransk; Stanton L Gerson
Potentiation of lymphomagenesis by methylnitrosourea in mice transgenic for LMO1 is blocked by O6-alkylguanine DNA-alkyltransferase.
Oncogene 1997;15(17):2127-32.
1996: Jane S Reese; Omer N Koç; K M Lee; Lili Liu; J A Allay; W P Phillips; Stanton L Gerson
Retroviral transduction of a mutant methylguanine DNA methyltransferase gene into human CD34 cells confers resistance to O6-benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):14088-93.
1996: Omer N Koç; J A Allay; K Lee; Brian M Davis; Jane S Reese; Stanton L Gerson
Transfer of drug resistance genes into hematopoietic progenitors to improve chemotherapy tolerance.
Seminars in oncology 1996;23(1):46-65.