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Manfred Reetz

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TOP 3
Gheorghe-Doru Roiban; Manfred T Reetz
Enzyme promiscuity: using a p450 enzyme as a carbene transfer catalyst.
Iakov Polyak; Manfred T Reetz; Walter Thiel
Quantum mechanical/molecular mechanical study on the enantioselectivity of the enzymatic baeyer-villiger reaction of 4-hydroxycyclohexanone.
Manfred T Reetz
The importance of additive and non-additive mutational effects in protein engineering.

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All Publications

2013: Gheorghe-Doru Roiban; Manfred T Reetz
Enzyme promiscuity: using a p450 enzyme as a carbene transfer catalyst.
Angewandte Chemie (International ed. in English) 2013;52(21):5439-40.
2013: Iakov Polyak; Manfred T Reetz; Walter Thiel
Quantum mechanical/molecular mechanical study on the enantioselectivity of the enzymatic baeyer-villiger reaction of 4-hydroxycyclohexanone.
The journal of physical chemistry. B 2013;117(17):4993-5001.
2013: Manfred T Reetz
The importance of additive and non-additive mutational effects in protein engineering.
Angewandte Chemie (International ed. in English) 2013;52(10):2658-66.
2013: Sabrina Kille; Diederik J Opperman; Loreto P Parra; Manfred T Reetz; Zhi-Gang Zhang; Carlos G Acevedo-Rocha; Juan Pablo Acevedo
Reducing codon redundancy and screening effort of combinatorial protein libraries created by saturation mutagenesis.
ACS synthetic biology 2013;2(2):83-92.
2013: Qi Wu; Pankaj Soni; Manfred T Reetz
Laboratory evolution of enantiocomplementary Candida antarctica lipase B mutants with broad substrate scope.
Journal of the American Chemical Society 2013;135(5):1872-81.
2013: Rubén Agudo; Gheorghe-Doru Roiban; Manfred T Reetz
Induced axial chirality in biocatalytic asymmetric ketone reduction.
Journal of the American Chemical Society 2013;135(5):1665-8.
2012: Zhi-Gang Zhang; Loreto P Parra; Manfred T Reetz
Protein engineering of stereoselective Baeyer-Villiger monooxygenases.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(33):10160-72.
2012: Manfred T Reetz
Artificial metalloenzymes as catalysts in stereoselective Diels-Alder reactions.
Chemical record (New York, N.Y.) 2012;12(4):391-406.
2012: Rubén Agudo; Gheorghe-Doru Roiban; Manfred T Reetz
Achieving regio- and enantioselectivity of P450-catalyzed oxidative CH activation of small functionalized molecules by structure-guided directed evolution.
Chembiochem : a European journal of chemical biology 2012;13(10):1465-73.
2012: Yosephine Gumulya; Joaquin Sanchis; Manfred T Reetz
Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minima.
Chembiochem : a European journal of chemical biology 2012;13(7):1060-6.
2012: Xiaojiang Feng; Manfred T Reetz; Joaquin Sanchis; Herschel Rabitz
Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(18):5646-54.
2012: Wojciech Augustyniak; Rolf Boelens; Agnieszka A Brzezinska; Bauke W Dijkstra; Tjaard Pijning; Hans Wienk; Manfred T Reetz
Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: factors contributing to increased activity retention.
Protein science : a publication of the Protein Society 2012;21(4):487-97.
2012: Iakov Polyak; Manfred T Reetz; Walter Thiel
Quantum mechanical/molecular mechanical study on the mechanism of the enzymatic Baeyer-Villiger reaction.
Journal of the American Chemical Society 2012;134(5):2732-41.
2011: Yosephine Gumulya; Manfred T Reetz
Enhancing the thermal robustness of an enzyme by directed evolution: least favorable starting points and inferior mutants can map superior evolutionary pathways.
Chembiochem : a European journal of chemical biology 2011;12(16):2502-10.
2011: Sabrina Kille; Juan P Acevedo; Felipe E Zilly; Manfred T Reetz
Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution.
Nature chemistry 2011;3(9):738-43.
2011: Manfred T Reetz; Huabao Zheng
Manipulating the expression rate and enantioselectivity of an epoxide hydrolase by using directed evolution.
Chembiochem : a European journal of chemical biology 2011;12(10):1529-35.
2011: Shreenath Prasad; Marco Bocola; Manfred T Reetz
Revisiting the lipase from Pseudomonas aeruginosa: directed evolution of substrate acceptance and enantioselectivity using iterative saturation mutagenesis.
Chemphyschem : a European journal of chemical physics and physical chemistry 2011;12(8):1550-7.
2011: Felipe E Zilly; Juan P Acevedo; Wojciech Augustyniak; Alfred Deege; Ulrich W Häusig; Manfred T Reetz
Tuning a p450 enzyme for methane oxidation.
Angewandte Chemie (International ed. in English) 2011;50(12):2720-4.
2011: Manfred T Reetz
Laboratory evolution of stereoselective enzymes: a prolific source of catalysts for asymmetric reactions.
Angewandte Chemie (International ed. in English) 2011;50(1):138-74.
2010: Diederik J Opperman; Manfred T Reetz
Towards practical Baeyer-Villiger-monooxygenases: design of cyclohexanone monooxygenase mutants with enhanced oxidative stability.
Chembiochem : a European journal of chemical biology 2010;11(18):2589-96.
2010: Manfred T Reetz; Pankaj Soni; Layla Fernández; Yosephine Gumulya; José Daniel Carballeira
Increasing the stability of an enzyme toward hostile organic solvents by directed evolution based on iterative saturation mutagenesis using the B-FIT method.
Chemical communications (Cambridge, England) 2010;46(45):8657-8.
2010: Huabao Zheng; Manfred T Reetz
Manipulating the stereoselectivity of limonene epoxide hydrolase by directed evolution based on iterative saturation mutagenesis.
Journal of the American Chemical Society 2010;132(44):15744-51.
2010: John Podtetenieff; Andreas Taglieber; Eckhard Bill; Edward J Reijerse; Manfred T Reetz
An artificial metalloenzyme: creation of a designed copper binding site in a thermostable protein.
Angewandte Chemie (International ed. in English) 2010;49(30):5151-5.
2010: Manfred T Reetz; Shreenath Prasad; José D Carballeira; Yosephine Gumulya; Marco Bocola
Iterative saturation mutagenesis accelerates laboratory evolution of enzyme stereoselectivity: rigorous comparison with traditional methods.
Journal of the American Chemical Society 2010;132(26):9144-52.
2010: Sheng Wu; Juan Pablo Acevedo; Manfred T Reetz
Induced allostery in the directed evolution of an enantioselective Baeyer-Villiger monooxygenase.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(7):2775-80.
2009: Felipe E Zilly; Andreas Taglieber; Frank Schulz; Frank Hollmann; Manfred T Reetz
Deazaflavins as mediators in light-driven cytochrome P450 catalyzed hydroxylations.
Chemical communications (Cambridge, England) 2009;(46):7152-4.
2009: Manfred T Reetz; Sheng Wu
Laboratory evolution of robust and enantioselective Baeyer-Villiger monooxygenases for asymmetric catalysis.
Journal of the American Chemical Society 2009;131(42):15424-32.
2009: Manfred T Reetz
Directed evolution of enantioselective enzymes: an unconventional approach to asymmetric catalysis in organic chemistry.
The Journal of organic chemistry 2009;74(16):5767-78.
2009: Manfred T Reetz; Marco Bocola; Li-Wen Wang; Joaquin Sanchis; Annette Cronin; Michael Arand; Jinyu Zou; Alain Archelas; Anne-Lise Bottalla; Agata Naworyta; Sherry L Mowbray
Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage.
Journal of the American Chemical Society 2009;131(21):7334-43.
2009: Manfred T Reetz; Pankaj Soni; Layla Fernández
Knowledge-guided laboratory evolution of protein thermolability.
Biotechnology and bioengineering 2009;102(6):1712-7.
2009: Manfred T Reetz; Hongchao Guo; Jun-An Ma; Richard Goddard; Richard Mynott
Helical triskelion monophosphites as ligands in asymmetric catalysis.
Journal of the American Chemical Society 2009;131(11):4136-42.
2009: Manfred T Reetz; Daniel Kahakeaw; Joaquin Sanchis
Shedding light on the efficacy of laboratory evolution based on iterative saturation mutagenesis.
Molecular bioSystems 2009;5(2):115-22.
2009: Manfred T Reetz; Pankaj Soni; Juan Pablo Acevedo; Joaquin Sanchis
Creation of an amino acid network of structurally coupled residues in the directed evolution of a thermostable enzyme.
Angewandte Chemie (International ed. in English) 2009;48(44):8268-72.
2008: Manfred T Reetz; Horst Höbenreich; Pankaj Soni; Layla Fernández
A genetic selection system for evolving enantioselectivity of enzymes.
Chemical communications (Cambridge, England) 2008;(43):5502-4.
2008: Manfred T Reetz; Sheng Wu
Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions.
Chemical communications (Cambridge, England) 2008;(43):5499-501.
2008: Joaquin Sanchis; Layla Fernández; J Daniel Carballeira; Jullien Drone; Yosephine Gumulya; Horst Höbenreich; Daniel Kahakeaw; Sabrina Kille; Renate Lohmer; Jérôme J-P Peyralans; John Podtetenieff; Shreenath Prasad; Pankaj Soni; Andreas Taglieber; Sheng Wu; Felipe E Zilly; Manfred T Reetz
Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates.
Applied microbiology and biotechnology 2008;81(2):387-97.
2008: Manfred T Reetz; Joaquin Sanchis
Constructing and analyzing the fitness landscape of an experimental evolutionary process.
Chembiochem : a European journal of chemical biology 2008;9(14):2260-7.
2008: Manfred T Reetz; Daniel Kahakeaw; Renate Lohmer
Addressing the numbers problem in directed evolution.
Chembiochem : a European journal of chemical biology 2008;9(11):1797-804.
2008: Andreas Taglieber; Frank Schulz; Frank Hollmann; Monika Rusek; Manfred T Reetz
Light-driven biocatalytic oxidation and reduction reactions: scope and limitations.
Chembiochem : a European journal of chemical biology 2008;9(4):565-72.
2008: Manfred T Reetz; Martin Rentzsch; Andreas Pletsch; Andreas Taglieber; Frank Hollmann; Régis J G Mondière; Norbert Dickmann; Birte Höcker; Simona Cerrone; Michaela Haeger; Reinhard Sterner
A robust protein host for anchoring chelating ligands and organocatalysts.
Chembiochem : a European journal of chemical biology 2008;9(4):552-64.
2008: Daniel Kahakeaw; Manfred T Reetz
A cell-based adrenaline assay for automated high-throughput activity screening of epoxide hydrolases.
Chemistry, an Asian journal 2008;3(2):233-8.
2008: Stefan Becker; Horst Höbenreich; Andreas Vogel; Janina Knorr; Susanne Wilhelm; Frank Rosenau; Karl-Erich Jaeger; Manfred T Reetz; Harald Kolmar
Single-cell high-throughput screening to identify enantioselective hydrolytic enzymes.
Angewandte Chemie (International ed. in English) 2008;47(27):5085-8.
2008: Manfred T Reetz
Combinatorial transition-metal catalysis: mixing monodentate ligands to control enantio-, diastereo-, and regioselectivity.
Angewandte Chemie (International ed. in English) 2008;47(14):2556-88.
2007: José Daniel Carballeira; Patrik Krumlinde; Marco Bocola; Andreas Vogel; Manfred T Reetz; Jan-E Bäckvall
Directed evolution and axial chirality: optimization of the enantioselectivity of Pseudomonas aeruginosa lipase towards the kinetic resolution of a racemic allene.
Chemical communications (Cambridge, England) 2007;(19):1913-5.
2007: Manfred T Reetz; Michael Puls; José Daniel Carballeira; Andreas Vogel; Karl-Erich Jaeger; Thorsten Eggert; Walter Thiel; Marco Bocola; Nikolaj Otte
Learning from directed evolution: Further lessons from theoretical investigations into cooperative mutations in lipase enantioselectivity.
Chembiochem : a European journal of chemical biology 2007;8(1):106-12.
2007: Manfred T Reetz; Benjamin List; Stefan Jaroch; Hilmar Weinmann
Organocatalysis. Berlin, April 2007. Preface.
Ernst Schering Foundation symposium proceedings 2007;(2):V-VIII.
2007: Manfred T Reetz
Controlling the selectivity and stability of proteins by new strategies in directed evolution: the case of organocatalytic enzymes.
Ernst Schering Foundation symposium proceedings 2007;(2):321-40.
2007: Andreas Taglieber; Horst Höbenreich; José Daniel Carballeira; Régis J G Mondière; Manfred T Reetz
Alternate-site enzyme promiscuity.
Angewandte Chemie (International ed. in English) 2007;46(45):8597-600.
2007: Manfred T Reetz; Oleg Bondarev
Mixtures of chiral phosphorous acid diesters and achiral p ligands in the enantio- and diastereoselective hydrogenation of ketimines.
Angewandte Chemie (International ed. in English) 2007;46(24):4523-6.
2007: Manfred T Reetz; José Daniel Carballeira
Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes.
Nature protocols 2007;2(4):891-903.
2007: Frank Hollmann; Andreas Taglieber; Frank Schulz; Manfred T Reetz
A light-driven stereoselective biocatalytic oxidation.
Angewandte Chemie (International ed. in English) 2007;46(16):2903-6.
2006: Manfred T Reetz; José Daniel Carballeira; Andreas Vogel
Iterative saturation mutagenesis on the basis of B factors as a strategy for increasing protein thermostability.
Angewandte Chemie (International ed. in English) 2006;45(46):7745-51.
2006: Manfred T Reetz; Jérôme J-P Peyralans; Andrea Maichele; Yu Fu; Matthias Maywald
Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein.
Chemical communications (Cambridge, England) 2006;(41):4318-20.
2006: Christopher M Clouthier; Margaret M Kayser; Manfred T Reetz
Designing new Baeyer-Villiger monooxygenases using restricted CASTing.
The Journal of organic chemistry 2006;71(22):8431-7.
2006: Manfred T Reetz; José Daniel Carballeira; Jérôme Peyralans; Horst Höbenreich; Andrea Maichele; Andreas Vogel
Expanding the substrate scope of enzymes: combining mutations obtained by CASTing.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(23):6031-8.
2006: Manfred T Reetz; Gerlinde Mehler; Oleg Bondarev
Chiral diphosphites and diphosphoramidites as cheap and efficient ligands in Rh-catalyzed asymmetric olefin hydrogenation.
Chemical communications (Cambridge, England) 2006;(21):2292-4.
2006: Manfred T Reetz; Xiaoguang Li
Asymmetric hydrogenation of quinolines catalyzed by iridium complexes of BINOL-derived diphosphonites.
Chemical communications (Cambridge, England) 2006;(20):2159-60.
2006: Manfred T Reetz; Li-Wen Wang
High-throughput selection system for assessing the activity of epoxide hydrolases.
Combinatorial chemistry & high throughput screening 2006;9(4):295-9.
2006: Manfred T Reetz; Ning Jiao
Copper-phthalocyanine conjugates of serum albumins as enantioselective catalysts in Diels-Alder reactions.
Angewandte Chemie (International ed. in English) 2006;45(15):2416-9.
2006: Detlev Belder; Martin Ludwig; Li-Wen Wang; Manfred T Reetz
Enantioselective catalysis and analysis on a chip.
Angewandte Chemie (International ed. in English) 2006;45(15):2463-6.
2006: Marko D Mihovilovic; Florian Rudroff; Alexander Winninger; Toni Schneider; Frank Schulz; Manfred T Reetz
Microbial Baeyer-Villiger oxidation: stereopreference and substrate acceptance of cyclohexanone monooxygenase mutants prepared by directed evolution.
Organic letters 2006;8(6):1221-4.
2006: Manfred T Reetz; Yu Fu; Andreas Meiswinkel
Nonlinear effects in Rh-catalyzed asymmetric olefin hydrogenation using mixtures of chiral monodentate P ligands.
Angewandte Chemie (International ed. in English) 2006;45(9):1412-5.
2006: Manfred T Reetz; Li-Wen Wang; Marco Bocola
Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space.
Angewandte Chemie (International ed. in English) 2006;45(8):1236-41.
2006: Manfred T Reetz; Xiaoguang Li
An efficient catalyst system for the asymmetric transfer hydrogenation of ketones: remarkably broad substrate scope.
Journal of the American Chemical Society 2006;128(4):1044-5.
2006: Melloney J Dröge; Ykelien L Boersma; Gertie van Pouderoyen; Titia E Vrenken; Carsten J Rüggeberg; Manfred T Reetz; Bauke W Dijkstra; Wim J Quax
Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection.
Chembiochem : a European journal of chemical biology 2006;7(1):149-57.
2005: Manfred T Reetz; Andreas Meiswinkel; Gerlinde Mehler; Klaus Angermund; Martin Graf; Walter Thiel; Richard Mynott; Donna G Blackmond
Why are BINOL-based monophosphites such efficient ligands in Rh-catalyzed asymmetric olefin hydrogenation?
Journal of the American Chemical Society 2005;127(29):10305-13.
2005: Manfred T Reetz; Marco Bocola; José Daniel Carballeira; Dongxing Zha; Andreas Vogel
Expanding the range of substrate acceptance of enzymes: combinatorial active-site saturation test.
Angewandte Chemie (International ed. in English) 2005;44(27):4192-6.
2005: Thorsten Eggert; Susanne Aileen Funke; Nalam Madhusudhana Rao; Priyamvada Acharya; Holger Krumm; Manfred T Reetz; Karl-Erich Jaeger
Multiplex-PCR-based recombination as a novel high-fidelity method for directed evolution.
Chembiochem : a European journal of chemical biology 2005;6(6):1062-7.
2005: Manfred T Reetz; Xiaoguang Li
Mixtures of configurationally stable and fluxional atropisomeric monodentate P ligands in asymmetric Rh-catalyzed olefin hydrogenation.
Angewandte Chemie (International ed. in English) 2005;44(19):2959-62.
2005: Manfred T Reetz; Xiaoguang Li
The influence of mixtures of monodentate achiral ligands on the regioselectivity of transition-metal-catalyzed hydroformylation.
Angewandte Chemie (International ed. in English) 2005;44(19):2962-4.
2005: Heiko Bernsmann; Michel van den Berg; Rob Hoen; Adriaan J Minnaard; Gerlinde Mehler; Manfred T Reetz; Johannes G de Vries; Ben L Feringa
PipPhos and MorfPhos: privileged monodentate phosphoramidite ligands for rhodium-catalyzed asymmetric hydrogenation.
The Journal of organic chemistry 2005;70(3):943-51.
2005: Manfred T Reetz; Jun-An Ma; Richard Goddard
Binol-derived monodentate phosphites and phosphoramidites with phosphorus stereogenic centers: novel ligands for transition-metal catalysis.
Angewandte Chemie (International ed. in English) 2005;44(3):412-5.
2005: Frank Schulz; François Leca; Frank Hollmann; Manfred T Reetz
Towards practical biocatalytic Baeyer-Villiger reactions: applying a thermostable enzyme in the gram-scale synthesis of optically-active lactones in a two-liquid-phase system.
Beilstein journal of organic chemistry 2005;1(1):10.
2005: Manfred T Reetz; Hongchao Guo
Mixtures of monodentate P-ligands as a means to control the diastereoselectivity in Rh-catalyzed hydrogenation of chiral alkenes.
Beilstein journal of organic chemistry 2005;1(1):3.
2004: Manfred T Reetz; Wolfgang Wiesenhöfer
Liquid poly(ethylene glycol) and supercritical carbon dioxide as a biphasic solvent system for lipase-catalyzed esterification.
Chemical communications (Cambridge, England) 2004;(23):2750-1.
2004: Manfred T Reetz; Franck Daligault; Birgit Brunner; Heike Hinrichs; Alfred Deege
Directed evolution of cyclohexanone monooxygenases: enantioselective biocatalysts for the oxidation of prochiral thioethers.
Angewandte Chemie (International ed. in English) 2004;43(31):4078-81.
2004: Manfred T Reetz; Birgit Brunner; Toni Schneider; Frank Schulz; Christopher M Clouthier; Margaret M Kayser
Directed evolution as a method to create enantioselective cyclohexanone monooxygenases for catalysis in Baeyer-Villiger reactions.
Angewandte Chemie (International ed. in English) 2004;43(31):4075-8.
2004: Manfred T Reetz; Johannes G de Vries
Ligand-free Heck reactions using low Pd-loading.
Chemical communications (Cambridge, England) 2004;(14):1559-63.
2004: Manfred T Reetz; Patrick Tielmann; Andreas Eipper; Alfred Ross; Gotz Schlotterbeck
A high-throughput NMR-based ee-assay using chemical shift imaging.
Chemical communications (Cambridge, England) 2004;(12):1366-7.
2004: Manfred T Reetz
Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):5716-22.
2004: Marco Bocola; Nikolaj Otte; Karl-Erich Jaeger; Manfred T Reetz; Walter Thiel
Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity.
Chembiochem : a European journal of chemical biology 2004;5(2):214-23.
2004: Manfred T Reetz; Claudia Torre; Andreas Eipper; Renate Lohmer; Marcus Hermes; Birgit Brunner; Andrea Maichele; Marco Bocola; Michael Arand; Annette Cronin; Yvonne Genzel; Alain Archelas; Roland Furstoss
Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution.
Organic letters 2004;6(2):177-80.
2004: Manfred T Reetz
Changing the enantioselectivity of enzymes by directed evolution.
Methods in enzymology 2004;388():238-56.
2003: Manfred T Reetz; Lukas J Goossen; Andreas Meiswinkel; Jens Paetzold; Jakob Feldthusen Jensen
Enantioselective Rh-catalyzed hydrogenation of vinyl carboxylates with monodentate phosphite ligands.
Organic letters 2003;5(17):3099-101.
2003: Patrick Tielmann; Matthias Boese; Martin Luft; Manfred T Reetz
A practical high-throughput screening system for enantioselectivity by using FTIR spectroscopy.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(16):3882-7.
2003: Melloney J Dröge; Carsten J Rüggeberg; Almer van der Sloot; Judith Schimmel; Dolf Swaving Dijkstra; Raymond M D Verhaert; Manfred T Reetz; Wim J Quax
Binding of phage displayed Bacillus subtilis lipase A to a phosphonate suicide inhibitor.
Journal of biotechnology 2003;101(1):19-28.
2003: Manfred T Reetz; Thorsten Sell; Andreas Meiswinkel; Gerlinde Mehler
A new principle in combinatorial asymmetric transition-metal catalysis: mixtures of chiral monodentate P ligands.
Angewandte Chemie (International ed. in English) 2003;42(7):790-3.
2003: Dongxing Zha; Andreas Eipper; Manfred T Reetz
Assembly of designed oligonucleotides as an efficient method for gene recombination: a new tool in directed evolution.
Chembiochem : a European journal of chemical biology 2003;4(1):34-9.
2003: Manfred T Reetz
Select protocols of high-throughput ee-screening systems for assaying enantioselective enzymes.
Methods in molecular biology (Clifton, N.J.) 2003;230():283-90.
2003: Manfred T Reetz
An overview of high-throughput screening systems for enantioselective enzymatic transformations.
Methods in molecular biology (Clifton, N.J.) 2003;230():259-82.
2002: Manfred T Reetz; Carsten J Rüggeberg
A screening system for enantioselective enzymes based on differential cell growth.
Chemical communications (Cambridge, England) 2002;(13):1428-9.
2002: Manfred T Reetz; Wolfgang Wiesenhöfer; Giancarlo Franciò; Walter Leitner
Biocatalysis in ionic liquids: batchwise and continuous flow processes using supercritical carbon dioxide as the mobile phase.
Chemical communications (Cambridge, England) 2002;(9):992-3.
2002: Manfred T Reetz
New methods for the high-throughput screening of enantioselective catalysts and biocatalysts.
Angewandte Chemie (International ed. in English) 2002;41(8):1335-8.
2002: Manfred T Reetz
Lipases as practical biocatalysts.
Current opinion in chemical biology 2002;6(2):145-50.
2001: Manfred T Reetz; D Moulin; A Gosberg
BINOL-based diphosphonites as ligands in the asymmetric Rh-catalyzed conjugate addition of arylboronic acids.
Organic letters 2001;3(25):4083-5.
2001: Manfred T Reetz; M Hermes; M H Becker
Infrared-thermographic screening of the activity and enantioselectivity of enzymes.
Applied microbiology and biotechnology 2001;55(5):531-6.
2001: Karl-Erich Jaeger; T Eggert; Andreas Eipper; Manfred T Reetz
Directed evolution and the creation of enantioselective biocatalysts.
Applied microbiology and biotechnology 2001;55(5):519-30.
2001: Manfred T Reetz; M Winter; R Breinbauer; T Thurn-Albrecht; W Vogel
Size-selective electrochemical preparation of surfactant-stabilized Pd-, Ni- and Pt/Pd colloids.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(5):1084-94.
2001: Alois Fürstner; D Voigtländer; W Schrader; D Giebel; Manfred T Reetz
A "hard/soft" mismatch enables catalytic Friedel-Crafts acylations.
Organic letters 2001;3(3):417-20.
2000: K Liebeton; A Zonta; K Schimossek; M Nardini; D Lang; Bauke W Dijkstra; Manfred T Reetz; Karl-Erich Jaeger
Directed evolution of an enantioselective lipase.
Chemistry & biology 2000;7(9):709-18.
2000: Manfred T Reetz; K M Kuhling; H Hinrichs; Alfred Deege
Circular dichroism as a detection method in the screening of enantioselective catalysts.
Chirality 2000;12(5-6):479-82.
2000: Manfred T Reetz; Karl-Erich Jaeger
Enantioselective enzymes for organic synthesis created by directed evolution.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(3):407-12.
2000: Karl-Erich Jaeger; Manfred T Reetz
Directed evolution of enantioselective enzymes for organic chemistry.
Current opinion in chemical biology 2000;4(1):68-73.
2000: Manfred T Reetz
Evolution in the test tube as a means to create enantioselective enzymes for use in organic synthesis.
Science progress 2000;83 ( Pt 2)():157-72.
1999: C Schmitz; Manfred T Reetz
Solid-phase enzymatic synthesis of oligonucleotides.
Organic letters 1999;1(11):1729-31.
1999: Karl-Erich Jaeger; B W Dijkstra; Manfred T Reetz
Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications of lipases.
Annual review of microbiology 1999;53():315-51.
1998: Karl-Erich Jaeger; Manfred T Reetz
Microbial lipases form versatile tools for biotechnology.
Trends in biotechnology 1998;16(9):396-403.
1998: Manfred T Reetz; Karl-Erich Jaeger
Overexpression, immobilization and biotechnological application of Pseudomonas lipases.
Chemistry and physics of lipids 1998;93(1-2):3-14.
1996: Manfred T Reetz; A Zonta; J Simpelkamp
Efficient immobilization of lipases by entrapment in hydrophobic sol-gel materials.
Biotechnology and bioengineering 1996;49(5):527-34.