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John Regan

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Sonemany Salinthone; Robynn V Schillace; Catherine Tsang; Dennis N Bourdette; John W Regan; Daniel W Carr
Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms.
Hiromichi Fujino; Kaori Toyomura; Xiao-bo Chen; John W Regan; Toshihiko Murayama
Prostaglandin E₂ regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells.
Anupama Chandramouli; Melania Mercado-Pimentel; Anthony Hutchinson; Adriana Gibadulinová; Erik R Olson; Sally Dickinson; Reneé Shañas; Jennifer Davenport; Janae Owens; Achyut K Bhattacharyya; John W Regan; Silvia Pastorekova; Thiruvengadam Arumugam; Craig D Logsdon; Mark A Nelson
The induction of S100p expression by the Prostaglandin E₂ (PGE₂)/EP4 receptor signaling pathway in colon cancer cells.

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All Publications

2011: Sonemany Salinthone; Robynn V Schillace; Catherine Tsang; Dennis N Bourdette; John W Regan; Daniel W Carr
Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms.
The Journal of nutritional biochemistry 2011;22(7):681-90.
2011: Hiromichi Fujino; Kaori Toyomura; Xiao-bo Chen; John W Regan; Toshihiko Murayama
Prostaglandin E₂ regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells.
Biochemical pharmacology 2011;81(3):379-87.
2010: Anupama Chandramouli; Melania Mercado-Pimentel; Anthony Hutchinson; Adriana Gibadulinová; Erik R Olson; Sally Dickinson; Reneé Shañas; Jennifer Davenport; Janae Owens; Achyut K Bhattacharyya; John W Regan; Silvia Pastorekova; Thiruvengadam Arumugam; Craig D Logsdon; Mark A Nelson
The induction of S100p expression by the Prostaglandin E₂ (PGE₂)/EP4 receptor signaling pathway in colon cancer cells.
Cancer biology & therapy 2010;10(10):1056-66.
2010: John W Regan; Sonia Létant; Kristl Adams; Nga Nguyen; Robert Derlet; Stuart H Cohen; Elizabeth Vitalis; Lance Tammero; Josue Ortiz; Mary McBride; James Birch
A sample-in-answer-out instrument for the detection of multiple respiratory pathogens in unprepared nasopharyngeal swab samples.
The Analyst 2010;135(9):2316-22.
2010: Ruyue Ji; Chih-Ling Chou; Wei Xu; Xiao-Bo Chen; David F Woodward; John W Regan
EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway.
Molecular pharmacology 2010;77(6):1025-36.
2010: Anthony J Hutchinson; Serena C Coons; Chih-Ling Chou; Wei Xu; W Daniel Stamer; David F Woodward; John W Regan
Induction of angiogenic immediate early genes by activation of FP prostanoid receptors in cultured human ciliary smooth muscle cells.
Current eye research 2010;35(5):408-18.
2010: Hiromichi Fujino; Toshihiko Murayama; John W Regan
Assessment of constitutive activity in E-type prostanoid receptors.
Methods in enzymology 2010;484():95-107.
2009: Anthony J Hutchinson; Chih-Ling Chou; Davelene D Israel; Wei Xu; John W Regan
Activation of EP2 prostanoid receptors in human glial cell lines stimulates the secretion of BDNF.
Neurochemistry international 2009;54(7):439-46.
2009: Wei Xu; Chih-Ling Chou; Davelene D Israel; Anthony J Hutchinson; John W Regan
PGF(2alpha) stimulates FP prostanoid receptor mediated crosstalk between Ras/Raf signaling and Tcf transcriptional activation.
Biochemical and biophysical research communications 2009;381(4):625-9.
2009: Davelene D Israel; John W Regan
EP(3) prostanoid receptor isoforms utilize distinct mechanisms to regulate ERK 1/2 activation.
Biochimica et biophysica acta 2009;1791(4):238-45.
2008: Tomoko Taniguchi; Hiromichi Fujino; Davelene D Israel; John W Regan; Toshihiko Murayama
Human EP3(I) prostanoid receptor induces VEGF and VEGF receptor-1 mRNA expression.
Biochemical and biophysical research communications 2008;377(4):1173-8.
2008: Wei Xu; Chih-Ling Chou; Haipeng Sun; Hiromichi Fujino; Qin M Chen; John W Regan
FP prostanoid receptor-mediated induction of the expression of early growth response factor-1 by activation of a Ras/Raf/mitogen-activated protein kinase signaling cascade.
Molecular pharmacology 2008;73(1):111-8.
2007: Durga P Cherukuri; Xiao-bo Chen; Anne-Christine Goulet; Robert N Young; Yongxin Han; Ronald L Heimark; John W Regan; Emmanuelle J Meuillet; Mark A Nelson
The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells.
Experimental cell research 2007;313(14):2969-79.
2007: Hiromichi Fujino; Xiao-bo Chen; John W Regan; Toshihiko Murayama
Indomethacin decreases EP2 prostanoid receptor expression in colon cancer cells.
Biochemical and biophysical research communications 2007;359(3):568-73.
2007: Masayuki Wada; Cynthia J DeLong; Yu H Hong; Caroline Jill Rieke; Inseok Song; Ranjinder Sidhu; Chong Yuan; Mark Warnock; Alvin H Schmaier; Chieko Yokoyama; Emer M Smyth; Stephen J Wilson; garret fitzgerald; R Michael Garavito; De Xin Sui; John W Regan; William L Smith
Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products.
The Journal of biological chemistry 2007;282(31):22254-66.
2006: Xiao-bo Chen; John W Regan
Activation of the human FP prostanoid receptor disrupts mitosis progression and generates aneuploidy and polyploidy.
Cellular and molecular life sciences : CMLS 2006;63(1):112-21.
2006: Hiromichi Fujino; John W Regan
EP(4) prostanoid receptor coupling to a pertussis toxin-sensitive inhibitory G protein.
Molecular pharmacology 2006;69(1):5-10.
2005: Hiromichi Fujino; Sambhitab Salvi; John W Regan
Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.
Molecular pharmacology 2005;68(1):251-9.
2004: Hiromichi Fujino; George A Vielhauer; John W Regan
Prostaglandin E2 selectively antagonizes prostaglandin F2alpha-stimulated T-cell factor/beta-catenin signaling pathway by the FPB prostanoid receptor.
The Journal of biological chemistry 2004;279(42):43386-91.
2004: Hiromichi Fujino; John W Regan
Prostaglandin F2alpha amplifies tumor necrosis factor-alpha promoter activity by the FPB prostanoid receptor.
Biochemical and biophysical research communications 2004;317(4):1114-20.
2004: George A Vielhauer; Hiromichi Fujino; John W Regan
Cloning and localization of hFP(S): a six-transmembrane mRNA splice variant of the human FP prostanoid receptor.
Archives of biochemistry and biophysics 2004;421(2):175-85.
2003: John W Regan
EP2 and EP4 prostanoid receptor signaling.
Life sciences 2003;74(2-3):143-53.
2003: Hiromichi Fujino; John W Regan
Prostanoid receptors and phosphatidylinositol 3-kinase: a pathway to cancer?
Trends in pharmacological sciences 2003;24(7):335-40.
2003: Hiromichi Fujino; Wei Xu; John W Regan
Prostaglandin E2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases.
The Journal of biological chemistry 2003;278(14):12151-6.
2003: Hiromichi Fujino; John W Regan
Prostaglandin F(2alpha) stimulation of cyclooxygenase-2 promoter activity by the FP(B) prostanoid receptor.
European journal of pharmacology 2003;465(1-2):39-41.
2003: Amy C Porter; Samuel P S Svensson; W Daniel Stamer; Joseph J Bahl; Jeremy G Richman; John W Regan
Alpha-2 adrenergic receptors stimulate actin organization in developing fetal rat cardiac myocytes.
Life sciences 2003;72(13):1455-66.
2002: Hiromichi Fujino; Dinesh Srinivasan; John W Regan
Cellular conditioning and activation of beta-catenin signaling by the FPB prostanoid receptor.
The Journal of biological chemistry 2002;277(50):48786-95.
2002: Thomas J Weber; Lye Meng Markillie; William B Chrisler; George A Vielhauer; John W Regan
Modulation of JB6 mouse epidermal cell transformation response by the prostaglandin F2alpha receptor.
Molecular carcinogenesis 2002;35(4):163-72.
2002: Dinesh Srinivasan; Hiromichi Fujino; John W Regan
Differential internalization of the prostaglandin f(2alpha) receptor isoforms: role of protein kinase C and clathrin.
The Journal of pharmacology and experimental therapeutics 2002;302(1):219-24.
2002: Todd L Anthony; Hiromichi Fujino; Kristen L Pierce; Andrea J Yool; John W Regan
Differential regulation of Ca(2+)-dependent Cl- currents by FP prostanoid receptor isoforms in Xenopus oocytes.
Biochemical pharmacology 2002;63(10):1797-806.
2002: Yi Huang; W Daniel Stamer; Todd L Anthony; David V Kumar; Paul A St John; John W Regan
Expression of alpha(2)-adrenergic receptor subtypes in prenatal rat spinal cord.
Brain research. Developmental brain research 2002;133(2):93-104.
2002: Hiromichi Fujino; Kimberly A West; John W Regan
Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.
The Journal of biological chemistry 2002;277(4):2614-9.
2001: Rennolds S Ostrom; Caroline Gregorian; R M Drenan; Y Xiang; John W Regan; Paul Insel
Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase.
The Journal of biological chemistry 2001;276(45):42063-9.
2001: Eric Thompson; A Gupta; George A Vielhauer; John W Regan; George Bowden
The growth of malignant keratinocytes depends on signaling through the PGE(2) receptor EP1.
Neoplasia (New York, N.Y.) 2001;3(5):402-10.
2001: Hiromichi Fujino; John W Regan
FP prostanoid receptor activation of a T-cell factor/beta -catenin signaling pathway.
The Journal of biological chemistry 2001;276(16):12489-92.
2000: Hiromichi Fujino; Kristen L Pierce; Dinesh Srinivasan; Charles E Protzman; Achim H-P Krauss; David F Woodward; John W Regan
Delayed reversal of shape change in cells expressing FP(B) prostanoid receptors. Possible role of receptor resensitization.
The Journal of biological chemistry 2000;275(38):29907-14.
2000: David F Woodward; Achim H-P Krauss; June Chen; Daniel W Gil; KM Kedzie; Charles E Protzman; L Shi; R Chen; HA Krauss; AM Bogardus; H T Dinh; Larry A Wheeler; SW Andrews; Robert M Burk; T Gac; M B Roof; Michael E Garst; L J Kaplan; G Sachs; Kristen L Pierce; John W Regan; R A Ross; Ming Fai Chan
Replacement of the carboxylic acid group of prostaglandin f(2alpha) with a hydroxyl or methoxy substituent provides biologically unique compounds.
British journal of pharmacology 2000;130(8):1933-43.
2000: Todd L Anthony; Kristen L Pierce; John W Regan
Characterization of ep prostanoid receptor subtypes in primary cultures of bovine ciliary epithelial cells by immunofluorescent microscopy and functional studies.
Current eye research 2000;20(5):394-404.
2000: Heddwen L Brooks; John W Regan; Andrea J Yool
Inhibition of aquaporin-1 water permeability by tetraethylammonium: involvement of the loop E pore region.
Molecular pharmacology 2000;57(5):1021-6.
2000: Todd L Anthony; Heddwen L Brooks; Daniela Boassa; S Leonov; Gina M Yanochko; John W Regan; Andrea J Yool
Cloned human aquaporin-1 is a cyclic GMP-gated ion channel.
Molecular pharmacology 2000;57(3):576-88.
2000: Hiromichi Fujino; Dinesh Srinivasan; Kristen L Pierce; John W Regan
Differential regulation of prostaglandin F(2alpha) receptor isoforms by protein kinase C.
Molecular pharmacology 2000;57(2):353-8.
1999: Kristen L Pierce; Hiromichi Fujino; Dinesh Srinivasan; John W Regan
Activation of FP prostanoid receptor isoforms leads to Rho-mediated changes in cell morphology and in the cell cytoskeleton.
The Journal of biological chemistry 1999;274(50):35944-9.
1999: Norbert H Fraeyman; Patrick Vanscheeuwijck; J M Wang; Y Huang; W P De Potter; John W Regan
Changes in the expression of alpha(2)-adrenergic receptor subtypes during maturation of neuronal cells from fetal pig superior cervical ganglia.
Brain research. Developmental brain research 1999;116(2):127-32.
1999: Patricia B Hoyer; Samuel L Marion; I Stine; Bo R Rueda; DL Hamernik; John W Regan; ME Wise
Ovine prostaglandin F2alpha receptor: steroid influence on steady-state levels of luteal mRNA.
Endocrine 1999;10(2):105-11.
1998: KM Kedzie; J E Donello; HA Krauss; John W Regan; Daniel W Gil
A single amino-acid substitution in the EP2 prostaglandin receptor confers responsiveness to prostacyclin analogs.
Molecular pharmacology 1998;54(3):584-90.
1998: Jeremy G Richman; John W Regan
Alpha 2-adrenergic receptors increase cell migration and decrease F-actin labeling in rat aortic smooth muscle cells.
The American journal of physiology 1998;274(3 Pt 1):C654-62.
1998: Todd L Anthony; Kristen L Pierce; W Daniel Stamer; John W Regan
Prostaglandin F2 alpha receptors in the human trabecular meshwork.
Investigative ophthalmology & visual science 1998;39(2):315-21.
1998: Kristen L Pierce; John W Regan
Prostanoid receptor heterogeneity through alternative mRNA splicing.
Life sciences 1998;62(17-18):1479-83.
1997: Tricia D LeVan; S B Dow; P B Chase; John W Bloom; John W Regan; E Cunningham; Marilyn Halonen
Evidence for platelet-activating factor receptor subtypes on human polymorphonuclear leukocyte membranes.
Biochemical pharmacology 1997;54(9):1007-12.
1997: Samuel P S Svensson; Amy C Porter; John W Regan
Cloning and functional expression of guinea pig atrial alpha 2-adrenergic receptor subtypes.
Annals of the New York Academy of Sciences 1997;812():171-3.
1997: David F Woodward; John W Regan; S Lake; A Ocklind
The molecular biology and ocular distribution of prostanoid receptors.
Survey of ophthalmology 1997;41 Suppl 2():S15-21.
1997: Kristen L Pierce; T J Bailey; Patricia B Hoyer; Daniel W Gil; David F Woodward; John W Regan
Cloning of a carboxyl-terminal isoform of the prostanoid FP receptor.
The Journal of biological chemistry 1997;272(2):883-7.
1996: W D Stamer; Robert W Snyder; John W Regan
Characterization of the transmembrane orientation of aquaporin-1 using antibodies to recombinant fusion proteins.
Biochemistry 1996;35(50):16313-8.
1996: W D Stamer; Y Huang; Richard E B Seftor; S S Svensson; Robert W Snyder; John W Regan
Cultured human trabecular meshwork cells express functional alpha 2A adrenergic receptors.
Investigative ophthalmology & visual science 1996;37(12):2426-33.
1996: Andrea J Yool; W D Stamer; John W Regan
Forskolin stimulation of water and cation permeability in aquaporin 1 water channels.
Science (New York, N.Y.) 1996;273(5279):1216-8.
1996: Samuel P S Svensson; T J Bailey; Amy C Porter; Jeremy G Richman; John W Regan
Heterologous expression of the cloned guinea pig alpha 2A, alpha 2B, and alpha 2C adrenoceptor subtypes. Radioligand binding and functional coupling to a CAMP-responsive reporter gene.
Biochemical pharmacology 1996;51(3):291-300.
1996: P B Chase; JM Yang; F H Thompson; Marilyn Halonen; John W Regan
Regional mapping of the human platelet-activating factor receptor gene (PTAFR) to 1p35-->p34.3 by fluorescence in situ hybridization.
Cytogenetics and cell genetics 1996;72(2-3):205-7.
1995: W D Stamer; Richard E B Seftor; Robert W Snyder; John W Regan
Cultured human trabecular meshwork cells express aquaporin-1 water channels.
Current eye research 1995;14(12):1095-1100.
1995: Y Huang; Daniel W Gil; Patrick Vanscheeuwijck; W D Stamer; John W Regan
Localization of alpha 2-adrenergic receptor subtypes in the anterior segment of the human eye with selective antibodies.
Investigative ophthalmology & visual science 1995;36(13):2729-39.
1995: David F Woodward; D J Pepperl; TH Burkey; John W Regan
6-Isopropoxy-9-oxoxanthene-2-carboxylic acid (AH 6809), a human EP2 receptor antagonist.
Biochemical pharmacology 1995;50(10):1731-3.
1995: Bo R Rueda; I W Botros; K L Pierce; John W Regan; Patricia B Hoyer
Comparison of mRNA levels for the PGF(2α) receptor (FP) during luteolysis and early pregnancy in the ovine corpus luteum.
Endocrine 1995;3(11):781-7.
1995: Penelope E Graves; Kristen L Pierce; T J Bailey; Bo R Rueda; Daniel W Gil; David F Woodward; Andrea J Yool; Patricia B Hoyer; John W Regan
Cloning of a receptor for prostaglandin F2 alpha from the ovine corpus luteum.
Endocrinology 1995;136(8):3430-6.
1995: Kristen L Pierce; Daniel W Gil; David F Woodward; John W Regan
Cloning of human prostanoid receptors.
Trends in pharmacological sciences 1995;16(8):253-6.
1995: TH Burkey; John W Regan
Activation of mitogen-activated protein kinase by the human prostaglandin EP3A receptor.
Biochemical and biophysical research communications 1995;211(1):152-8.
1995: D B Bylund; John W Regan; James E Faber; J P Hieble; C R Triggle; R R Ruffolo
Vascular alpha-adrenoceptors: from the gene to the human.
Canadian journal of physiology and pharmacology 1995;73(5):533-43.
1994: W D Stamer; Robert W Snyder; B L Smith; Peter Agre; John W Regan
Localization of aquaporin CHIP in the human eye: implications in the pathogenesis of glaucoma and other disorders of ocular fluid balance.
Investigative ophthalmology & visual science 1994;35(11):3867-72.
1994: John W Regan; T J Bailey; D J Pepperl; Kristen L Pierce; A M Bogardus; J E Donello; C E Fairbairn; K M Kedzie; David F Woodward; Daniel W Gil
Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype.
Molecular pharmacology 1994;46(2):213-20.
1994: John W Regan; T J Bailey; J E Donello; Kristen L Pierce; D J Pepperl; D Zhang; K M Kedzie; C E Fairbairn; A M Bogardus; David F Woodward
Molecular cloning and expression of human EP3 receptors: evidence of three variants with differing carboxyl termini.
British journal of pharmacology 1994;112(2):377-85.
1993: Y Huang; Patrick Vanscheeuwijck; John W Regan
Precipitation with KCl improves the chemical cross-linking of GST-fusion proteins to agarose after solubilization with SDS.
BioTechniques 1993;15(6):989-92.
1993: D J Pepperl; John W Regan
Selective coupling of alpha 2-adrenergic receptor subtypes to cyclic AMP-dependent reporter gene expression in transiently transfected JEG-3 cells.
Molecular pharmacology 1993;44(4):802-9.
1993: Samuel P S Svensson; T J Bailey; D J Pepperl; N Grundström; S Ala-Uotila; Mika Scheinin; Jan Olof Gustav Karlsson; John W Regan
Cloning and expression of a fish alpha 2-adrenoceptor.
British journal of pharmacology 1993;110(1):54-60.
1993: P B Chase; Marilyn Halonen; John W Regan
Cloning of a human platelet-activating factor receptor gene: evidence for an intron in the 5'-untranslated region.
American journal of respiratory cell and molecular biology 1993;8(3):240-4.
1993: Patrick Vanscheeuwijck; Y Huang; D Schullery; John W Regan
Antibodies to a human alpha 2-C10 adrenergic receptor fusion protein confirm the cytoplasmic orientation of the V-VI loop.
Biochemical and biophysical research communications 1993;190(2):340-6.
1992: Maritta Perälä; H Hirvonen; H Kalimo; S Ala-Uotila; John W Regan; K E Akerman; Mika Scheinin
Differential expression of two alpha 2-adrenergic receptor subtype mRNAs in human tissues.
Brain research. Molecular brain research 1992;16(1-2):57-63.
1992: L Sun; N Schulte; P Pettinger; John W Regan; W A Pettinger
The frequency of alpha 2-adrenoceptor restriction fragment length polymorphisms in normotensive and hypertensive humans.
Journal of hypertension 1992;10(9):1011-5.
1992: Anne Marjamäki; S Ala-Uotila; K Luomala; Maritta Perälä; CC Jansson; Markku Jalkanen; John W Regan; Mika Scheinin
Stable expression of recombinant human alpha 2-adrenoceptor subtypes in two mammalian cell lines: characterization with [3H]rauwolscine binding, inhibition of adenylate cyclase and RNase protection assay.
Biochimica et biophysica acta 1992;1134(2):169-77.
1991: K M Kedzie; Celia A Balfour; G Y Escobar; S W Grimm; You Ai He; D J Pepperl; John W Regan; JC Stevens; James Halpert
Molecular basis for a functionally unique cytochrome P450IIB1 variant.
The Journal of biological chemistry 1991;266(33):22515-21.
1991: A L Parola; D G Stump; D J Pepperl; K E Krueger; John W Regan; H E Laird
Cloning and expression of a pharmacologically unique bovine peripheral-type benzodiazepine receptor isoquinoline binding protein.
The Journal of biological chemistry 1991;266(21):14082-7.
1991: J J Onorato; K Palczewski; John W Regan; Marc G Caron; R J Lefkowitz; J L Benovic
Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase.
Biochemistry 1991;30(21):5118-25.
1991: H Kurose; John W Regan; Marc G Caron; R J Lefkowitz
Functional interactions of recombinant alpha 2 adrenergic receptor subtypes and G proteins in reconstituted phospholipid vesicles.
Biochemistry 1991;30(13):3335-41.
1991: Mervyn Maze; John W Regan
Role of signal transduction in anesthetic action. Alpha 2 adrenergic agonists.
Annals of the New York Academy of Sciences 1991;625():409-22.
1990: W Lorenz; J W Lomasney; Sheila Collins; John W Regan; Marc G Caron; R J Lefkowitz
Expression of three alpha 2-adrenergic receptor subtypes in rat tissues: implications for alpha 2 receptor classification.
Molecular pharmacology 1990;38(5):599-603.
1990: J W Lomasney; W Lorenz; L F Allen; K King; John W Regan; T L Yang-Feng; Marc G Caron; R J Lefkowitz
Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):5094-8.
1990: K Seuwen; I Magnaldo; B K Kobilka; Marc G Caron; John W Regan; R J Lefkowitz; Jacques Pouysségur
Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene.
Cell regulation 1990;1(6):445-51.
1990: S Cotecchia; B K Kobilka; Kiefer W Daniel; R D Nolan; E Y Lapetina; Marc G Caron; R J Lefkowitz; John W Regan
Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells.
The Journal of biological chemistry 1990;265(1):63-9.
1990: Martin C Michel; John W Regan; M A Gerhardt; Richard Neubig; Paul Insel; H J Motulsky
Nonadrenergic [3H]idazoxan binding sites are physically distinct from alpha 2-adrenergic receptors.
Molecular pharmacology 1990;37(1):65-8.
1989: Margret R Hoehe; Wade H Berrettini; John W Regan
A biallelic RFLP of the human alpha 2-C4 adrenergic receptor gene (ADRA2RL2) localized on the short arm of chromosome 4 and encoding the putative alpha 2B receptor is identified with Bsu 36 I, using a 1.5 kb probe (p ADRA2RL2).
Nucleic acids research 1989;17(23):10148.
1989: A Fargin; John R Raymond; John W Regan; S Cotecchia; R J Lefkowitz; Marc G Caron
Effector coupling mechanisms of the cloned 5-HT1A receptor.
The Journal of biological chemistry 1989;264(25):14848-52.
1989: John R Raymond; A Fargin; M J Lohse; John W Regan; S E Senogles; R J Lefkowitz; Marc G Caron
Identification of the ligand-binding subunit of the human 5-hydroxytryptamine1A receptor with N-(p-azido-m-[125I] iodophenethyl)spiperone, a high affinity radioiodinated photoaffinity probe.
Molecular pharmacology 1989;36(1):15-21.
1989: H Matsui; R J Lefkowitz; Marc G Caron; John W Regan
Localization of the fourth membrane spanning domain as a ligand binding site in the human platelet alpha 2-adrenergic receptor.
Biochemistry 1989;28(9):4125-30.
1988: B F O'Dowd; M Hnatowich; John W Regan; W M Leader; Marc G Caron; R J Lefkowitz
Site-directed mutagenesis of the cytoplasmic domains of the human beta 2-adrenergic receptor. Localization of regions involved in G protein-receptor coupling.
The Journal of biological chemistry 1988;263(31):15985-92.
1988: R N Daly; Anthony C Sulpizio; B Levitt; R M DeMarinis; John W Regan; RR Ruffolo; J Paul Hieble
Evidence for heterogeneity between pre- and postjunctional alpha-2 adrenoceptors using 9-substituted 3-benzazepines.
The Journal of pharmacology and experimental therapeutics 1988;247(1):122-8.
1988: John W Regan; T S Kobilka; T L Yang-Feng; Marc G Caron; R J Lefkowitz; B K Kobilka
Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6301-5.
1988: B K Kobilka; T S Kobilka; Kiefer W Daniel; John W Regan; Marc G Caron; R J Lefkowitz
Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity.
Science (New York, N.Y.) 1988;240(4857):1310-6.
1988: R J Lefkowitz; B K Kobilka; J L Benovic; Michel Bouvier; S Cotecchia; W P Hausdorff; Henrik G Dohlman; John W Regan; Marc G Caron
Molecular biology of adrenergic receptors.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():507-14.
1987: J L Benovic; John W Regan; H Matsui; F Mayor; S Cotecchia; L M Fredrik Leeb-Lundberg; Marc G Caron; R J Lefkowitz
Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase.
The Journal of biological chemistry 1987;262(36):17251-3.
1987: B K Kobilka; H Matsui; T S Kobilka; T L Yang-Feng; U Francke; Marc G Caron; R J Lefkowitz; John W Regan
Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor.
Science (New York, N.Y.) 1987;238(4827):650-6.
1986: H Nakata; John W Regan; R J Lefkowitz
Chemical modification of alpha 2-adrenoceptors. Possible role for tyrosine in the ligand binding site.
Biochemical pharmacology 1986;35(22):4089-94.
1986: J W Lomasney; L M Fredrik Leeb-Lundberg; S Cotecchia; John W Regan; J F DeBernardis; Marc G Caron; R J Lefkowitz
Mammalian alpha 1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit.
The Journal of biological chemistry 1986;261(17):7710-6.
1986: John W Regan; John R Raymond; R J Lefkowitz; R M DeMarinis
Photoaffinity labeling of human platelet and rabbit kidney alpha 2-adrenoceptors with [3H]SKF 102229.
Biochemical and biophysical research communications 1986;137(2):606-13.
1986: R A Cerione; John W Regan; H Nakata; J Codina; J L Benovic; P Gierschik; R L Somers; Allen Spiegel; Lutz Birnbaumer; R J Lefkowitz
Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles.
The Journal of biological chemistry 1986;261(8):3901-9.
1986: John W Regan; H Nakata; R M DeMarinis; Marc G Caron; R J Lefkowitz
Purification and characterization of the human platelet alpha 2-adrenergic receptor.
The Journal of biological chemistry 1986;261(8):3894-900.
1985: John W Regan; R M DeMarinis; R J Lefkowitz
Arylazide photoaffinity probe for alpha 2-adrenoceptors.
Biochemical pharmacology 1985;34(20):3667-72.
1984: R M DeMarinis; A J Krog; D H Shah; J Lafferty; K G Holden; J Paul Hieble; W D Matthews; John W Regan; R J Lefkowitz; Marc G Caron
Development of an affinity ligand for purification of alpha 2-adrenoceptors from human platelet membranes.
Journal of medicinal chemistry 1984;27(7):918-21.
1984: John W Regan; R M DeMarinis; Marc G Caron; R J Lefkowitz
Identification of the subunit-binding site of alpha 2-adrenergic receptors using [3H]phenoxybenzamine.
The Journal of biological chemistry 1984;259(12):7864-9.
1982: John W Regan; N Barden; R J Lefkowitz; Marc G Caron; R M DeMarinis; A J Krog; K G Holden; W D Matthews; J Paul Hieble
Affinity chromatography of human platelet alpha 2-adrenergic receptors.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(23):7223-7.
1981: John W Regan; W R Roeske; J B Malick; S H Yamamura; Henry I Yamamura
gamma-Aminobutyric acid enhancement of CL 218,872 affinity and evidence of benzodiazepine receptor heterogeneity.
Molecular pharmacology 1981;20(3):477-83.
1981: John W Regan; W R Roeske; W H Ruth; P Deshmukh; Henry I Yamamura
Reductions in retinal gamma-aminobutyric acid (GABA) content and in [3H]flunitrazepam binding after postnatal monosodium glutamate injections in rats.
The Journal of pharmacology and experimental therapeutics 1981;218(3):791-6.
1981: John W Regan; Henry I Yamamura; S Yamada; W R Roeske
High affinity [3H]flunitrazepam binding: characterization, localization, and alteration in hypertension.
Life sciences 1981;28(9):991-8.
1980: John W Regan; M M Morris; B Nao; Leonard F Bjeldanes
Metabolism of limonene-1,2-epoxide in the rat.
Xenobiotica; the fate of foreign compounds in biological systems 1980;10(12):859-61.
1980: John W Regan; Henry I Yamamura; S Yamada; W R Roeske
Renal benzodiazepine binding increases during deoxycorticosterone/salt hypertension in rats.
European journal of pharmacology 1980;67(1):167-8.
1980: R C Speth; R W Johnson; John W Regan; T Reisine; R M Kobayashi; N Bresolin; W R Roeske; Henry I Yamamura
The benzodiazepine receptor of mammalian brain.
Federation proceedings 1980;39(12):3032-8.
1980: John W Regan; W R Roeske; Henry I Yamamura
3H-Flunitrazepam binding to bovine retina and the effect of GABA thereon.
Neuropharmacology 1980;19(4):413-4.
1980: John W Regan; W R Roeske; Henry I Yamamura
The benzodiazepine receptor: its development and its modulation by gamma-aminobutyric acid.
The Journal of pharmacology and experimental therapeutics 1980;212(1):137-43.
1976: John W Regan; L F Bjeldanes
Metabolism of (+)-limonene in rats.
Journal of agricultural and food chemistry 1976;24(2):377-80.
1974: J R Mainoya; H A Bern; John W Regan
Influence of ovine prolactin on transport of fluid and sodium chloride by the mammalian intestine and gall bladder.
The Journal of endocrinology 1974;63(2):311-7.
1971: John W Regan
Guilt, perceived injustice, and altruistic behavior.
Journal of personality and social psychology 1971;18(1):124-32.
1969: P J Cousins; John W Regan
Clinical evaluation of Babisan in 200 infants.
Nursing times 1969;65(16):501-2.