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Kenneth Reid

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Anne Jäkel; Howard Clark; Kenneth B M Reid; Robert B Sim
The human lung surfactant proteins A (SP-A) and D (SP-D) interact with apoptotic target cells by different binding mechanisms.
Anne Jäkel; Howard Clark; Kenneth B M Reid; Robert B Sim
Surface-bound myeloperoxidase is a ligand for recognition of late apoptotic neutrophils by human lung surfactant proteins A and D.
Taruna Madan; Kenneth B M Reid; Howard Clark; Mamta Singh; Annapurna Nayak; P Usha Sarma; Samuel Hawgood; Uday Kishore
Susceptibility of mice genetically deficient in SP-A or SP-D gene to invasive pulmonary aspergillosis.

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All Publications

2010: Anne Jäkel; Howard Clark; Kenneth B M Reid; Robert B Sim
The human lung surfactant proteins A (SP-A) and D (SP-D) interact with apoptotic target cells by different binding mechanisms.
Immunobiology 2010;215(7):551-8.
2010: Anne Jäkel; Howard Clark; Kenneth B M Reid; Robert B Sim
Surface-bound myeloperoxidase is a ligand for recognition of late apoptotic neutrophils by human lung surfactant proteins A and D.
Protein & cell 2010;1(6):563-72.
2010: Taruna Madan; Kenneth B M Reid; Howard Clark; Mamta Singh; Annapurna Nayak; P Usha Sarma; Samuel Hawgood; Uday Kishore
Susceptibility of mice genetically deficient in SP-A or SP-D gene to invasive pulmonary aspergillosis.
Molecular immunology 2010;47(10):1923-30.
2010: Anne Jäkel; Kenneth B M Reid; Howard Clark
Surfactant protein A (SP-A) binds to phosphatidylserine and competes with annexin V binding on late apoptotic cells.
Protein & cell 2010;1(2):188-97.
2010: Jason W K Goh; Yen Seah Tan; Alister W Dodds; Kenneth B M Reid; Jinhua Lu
The class A macrophage scavenger receptor type I (SR-AI) recognizes complement iC3b and mediates NF-κB activation.
Protein & cell 2010;1(2):174-87.
2009: Annette K Shrive; C Martin; I Burns; J M Paterson; J D Martin; J P Townsend; Patrick Waters; H W Clark; Uday Kishore; Kenneth B M Reid; Trevor J Greenhough
Structural characterisation of ligand-binding determinants in human lung surfactant protein D: influence of Asp325.
Journal of molecular biology 2009;394(4):776-88.
2009: Anna E Phillips; Julia Toth; Alister W Dodds; Umakhanth Venkatraman Girija; Christopher M Furze; Eleni Pala; Robert B Sim; Kenneth B M Reid; Wilhelm J Schwaeble; Ralf Schmid; Anthony H Keeble; Russell Wallis
Analogous interactions in initiating complexes of the classical and lectin pathways of complement.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7708-17.
2009: Kenneth B M Reid
Target pattern recognition in innate immunity. Foreword.
Advances in experimental medicine and biology 2009;653():vii-viii.
2008: Mihaela G Gadjeva; Marieta M Rouseva; Alexandra S Zlatarova; Kenneth B M Reid; Uday Kishore; Mihaela S Kojouharova
Interaction of human C1q with IgG and IgM: revisited.
Biochemistry 2008;47(49):13093-102.
2008: Gaurav D Gaiha; Tao Dong; Nades Palaniyar; Daniel A Mitchell; Kenneth B M Reid; Howard W Clark
Surfactant protein A binds to HIV and inhibits direct infection of CD4+ cells, but enhances dendritic cell-mediated viral transfer.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):601-9.
2008: Jin Hua Lu; Boon King Teh; Lin da Wang; Yi Nan Wang; Yen Seah Tan; Min Chern Lai; Kenneth B M Reid
The classical and regulatory functions of C1q in immunity and autoimmunity.
Cellular & molecular immunology 2008;5(1):9-21.
2007: Umakhanth Venkatraman Girija; Alister W Dodds; Silke Roscher; Kenneth B M Reid; Russell Wallis
Localization and characterization of the mannose-binding lectin (MBL)-associated-serine protease-2 binding site in rat ficolin-A: equivalent binding sites within the collagenous domains of MBLs and ficolins.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(1):455-62.
2007: Wafa Khamri; Mulugeta L Worku; Amy E Anderson; Marjorie M Walker; Samuel Hawgood; Kenneth B M Reid; Howard W Clark; Mark Thursz
Helicobacter infection in the surfactant protein D-deficient mouse.
Helicobacter 2007;12(2):112-23.
2007: Russell Wallis; Alister W Dodds; Daniel A Mitchell; Robert B Sim; Kenneth B M Reid; Wilhelm J Schwaeble
Molecular interactions between MASP-2, C4, and C2 and their activation fragments leading to complement activation via the lectin pathway.
The Journal of biological chemistry 2007;282(11):7844-51.
2007: Jiu-Yao Wang; Kenneth B M Reid
The immunoregulatory roles of lung surfactant collectins SP-A, and SP-D, in allergen-induced airway inflammation.
Immunobiology 2007;212(4-5):417-25.
2007: Rohit Ghai; Patrick Waters; Lubka T Roumenina; Mihaela Gadjeva; Mihaela S Kojouharova; Kenneth B M Reid; Robert B Sim; Uday Kishore
C1q and its growing family.
Immunobiology 2007;212(4-5):253-66.
2006: Alexandra S Zlatarova; Marieta Rouseva; Lubka T Roumenina; Mihaela Gadjeva; Martin Kolev; Ivan Dobrev; Neli Olova; Rohit Ghai; Jens C Jensenius; Kenneth B M Reid; Uday Kishore; Mihaela S Kojouharova
Existence of different but overlapping IgG- and IgM-binding sites on the globular domain of human C1q.
Biochemistry 2006;45(33):9979-88.
2006: Grith L Sorensen; Jens Madsen; Karin Kejling; Ida Tornoe; Ole Nielsen; Paul Townsend; Francis Poulain; Claus Henrik Nielsen; Kenneth B M Reid; Samuel Hawgood; Erling Falk; Uffe Holmskov
Surfactant protein D is proatherogenic in mice.
American journal of physiology. Heart and circulatory physiology 2006;290(6):H2286-94.
2006: Suzanne Donnelly; Wendy Roake; Simon Brown; Philip Young; Haley Naik; Paul Wordsworth; David A Isenberg; Kenneth B M Reid; Paul Eggleton
Impaired recognition of apoptotic neutrophils by the C1q/calreticulin and CD91 pathway in systemic lupus erythematosus.
Arthritis and rheumatism 2006;54(5):1543-56.
2006: Lubka T Roumenina; Marieta M Ruseva; Alexandra S Zlatarova; Rohit Ghai; Martin Kolev; Neli Olova; Mihaela Gadjeva; Alok Agrawal; Barbara Bottazzi; Alberto Mantovani; Kenneth B M Reid; Uday Kishore; Mihaela S Kojouharova
Interaction of C1q with IgG1, C-reactive protein and pentraxin 3: mutational studies using recombinant globular head modules of human C1q A, B, and C chains.
Biochemistry 2006;45(13):4093-104.
2006: Uday Kishore; Trevor J Greenhough; Patrick Waters; Annette K Shrive; Rohit Ghai; mo kamran; Andrés López Bernal; Kenneth B M Reid; Taruna Madan; Trinad Chakraborty
Surfactant proteins SP-A and SP-D: structure, function and receptors.
Molecular immunology 2006;43(9):1293-315.
2005: Chai-Fan Liu; Yi-Lin Chen; Wen-Tsan Chang; Chi-Chang Shieh; Chun-Keung Yu; Kenneth B M Reid; Jiu-Yao Wang
Mite allergen induces nitric oxide production in alveolar macrophage cell lines via CD14/toll-like receptor 4, and is inhibited by surfactant protein D.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(12):1615-24.
2005: Russell Wallis; Nicholas J Lynch; Silke Roscher; Kenneth B M Reid; Wilhelm J Schwaeble
Decoupling of carbohydrate binding and MASP-2 autoactivation in variant mannose-binding lectins associated with immunodeficiency.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6846-51.
2005: Lubka T Roumenina; Alexander A Kantardjiev; Boris P Atanasov; Patrick Waters; Mihaela Gadjeva; Kenneth B M Reid; Alberto Mantovani; Uday Kishore; Mihaela S Kojouharova
Role of Ca2+ in the electrostatic stability and the functional activity of the globular domain of human C1q.
Biochemistry 2005;44(43):14097-109.
2005: Wafa Khamri; Anthony P Moran; Mulugeta L Worku; Q Najma Karim; Marjorie M Walker; Heidi Annuk; John A Ferris; Ben J Appelmelk; Paul Eggleton; Kenneth B M Reid; Mark Thursz
Variations in Helicobacter pylori lipopolysaccharide to evade the innate immune component surfactant protein D.
Infection and immunity 2005;73(11):7677-86.
2005: Jeya Nadesalingam; Kenneth B M Reid; Nades Palaniyar
Collectin surfactant protein D binds antibodies and interlinks innate and adaptive immune systems.
FEBS letters 2005;579(20):4449-53.
2005: Kenneth B M Reid; Howard Clark; Nades Palaniyar
Surfactant and lung inflammation.
Thorax 2005;60(8):620-2.
2005: Jeya Nadesalingam; Alister W Dodds; Kenneth B M Reid; Nades Palaniyar
Mannose-binding lectin recognizes peptidoglycan via the N-acetyl glucosamine moiety, and inhibits ligand-induced proinflammatory effect and promotes chemokine production by macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1785-94.
2005: Nades Palaniyar; Howard Clark; Jeya Nadesalingam; Michael J Shih; Samuel Hawgood; Kenneth B M Reid
Innate immune collectin surfactant protein D enhances the clearance of DNA by macrophages and minimizes anti-DNA antibody generation.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7352-8.
2005: Taruna Madan; Kenneth B M Reid; Mamta Singh; P Usha Sarma; Uday Kishore
Susceptibility of mice genetically deficient in the surfactant protein (SP)-A or SP-D gene to pulmonary hypersensitivity induced by antigens and allergens of Aspergillus fumigatus.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):6943-54.
2005: Weiqun Kang; Ole Nielsen; Claus Fenger; Graham Leslie; Uffe Holmskov; Kenneth B M Reid
Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer.
Carcinogenesis 2005;26(6):1129-37.
2005: Taruna Madan; S Kaur; Shweta Saxena; M Singh; Uday Kishore; S Thiel; Kenneth B M Reid; P Usha Sarma
Role of collectins in innate immunity against aspergillosis.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2005;43 Suppl 1():S155-63.
2005: Chai-Fan Liu; Yi-Lin Chen; Chi-Chang Shieh; Chun-Keung Yu; Kenneth B M Reid; Jiu-Yao Wang
Therapeutic effect of surfactant protein D in allergic inflammation of mite-sensitized mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(4):515-21.
2004: Zhe Sun; Kenneth B M Reid; Stephen J Perkins
The dimeric and trimeric solution structures of the multidomain complement protein properdin by X-ray scattering, analytical ultracentrifugation and constrained modelling.
Journal of molecular biology 2004;343(5):1327-43.
2004: Uday Kishore; Christine Gaboriaud; Patrick Waters; Annette K Shrive; Trevor J Greenhough; Kenneth B M Reid; Robert B Sim; Gérard J Arlaud
C1q and tumor necrosis factor superfamily: modularity and versatility.
Trends in immunology 2004;25(10):551-61.
2004: Nades Palaniyar; Jeya Nadesalingam; Howard Clark; Michael J Shih; Alister W Dodds; Kenneth B M Reid
Nucleic acid is a novel ligand for innate, immune pattern recognition collectins surfactant proteins A and D and mannose-binding lectin.
The Journal of biological chemistry 2004;279(31):32728-36.
2004: Paul J Tacken; Kevan L Hartshorn; Mitchell R White; Cees van Kooten; Jan G J van de Winkel; Kenneth B M Reid; Joseph J Batenburg
Effective targeting of pathogens to neutrophils via chimeric surfactant protein D/anti-CD89 protein.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(8):4934-40.
2004: Mihaela S Kojouharova; Mihaela Gadjeva; Ivanka G Tsacheva; Alexandra S Zlatarova; Lubka T Roumenina; Magdalena I Tchorbadjieva; Boris P Atanasov; Patrick Waters; Britta C Urban; Robert B Sim; Kenneth B M Reid; Uday Kishore
Mutational analyses of the recombinant globular regions of human C1q A, B, and C chains suggest an essential role for arginine and histidine residues in the C1q-IgG interaction.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4351-8.
2003: Nades Palaniyar; Howard Clark; Jeya Nadesalingam; Samuel Hawgood; Kenneth B M Reid
Surfactant protein D binds genomic DNA and apoptotic cells, and enhances their clearance, in vivo.
Annals of the New York Academy of Sciences 2003;1010():471-5.
2003: Nades Palaniyar; Jeya Nadesalingam; Kenneth B M Reid
Innate immune collectins bind nucleic acids and enhance DNA clearance in vitro.
Annals of the New York Academy of Sciences 2003;1010():467-70.
2003: Howard Clark; Nades Palaniyar; Samuel Hawgood; Kenneth B M Reid
A recombinant fragment of human surfactant protein D reduces alveolar macrophage apoptosis and pro-inflammatory cytokines in mice developing pulmonary emphysema.
Annals of the New York Academy of Sciences 2003;1010():113-6.
2003: Mihaela S Kojouharova; Ivanka G Tsacheva; Magdalena I Tchorbadjieva; Kenneth B M Reid; Uday Kishore
Localization of ligand-binding sites on human C1q globular head region using recombinant globular head fragments and single-chain antibodies.
Biochimica et biophysica acta 2003;1652(1):64-74.
2003: Peter Strong; P Townsend; R Mackay; Kenneth B M Reid; Howard W Clark
A recombinant fragment of human SP-D reduces allergic responses in mice sensitized to house dust mite allergens.
Clinical and experimental immunology 2003;134(2):181-7.
2003: Annette K Shrive; Hazel A Tharia; Peter Strong; Uday Kishore; Ian Burns; Pierre J Rizkallah; Kenneth B M Reid; Trevor J Greenhough
High-resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D.
Journal of molecular biology 2003;331(2):509-23.
2003: Uday Kishore; Sanjeev K Gupta; Michael V Perdikoulis; Mihaela S Kojouharova; Britta C Urban; Kenneth B M Reid
Modular organization of the carboxyl-terminal, globular head region of human C1q A, B, and C chains.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):812-20.
2003: Jeya Nadesalingam; Andrés López Bernal; Alister W Dodds; Antony C Willis; David J Mahoney; Anthony J Day; Kenneth B M Reid; Nades Palaniyar
Identification and characterization of a novel interaction between pulmonary surfactant protein D and decorin.
The Journal of biological chemistry 2003;278(28):25678-87.
2003: Weiqun Kang; Kenneth B M Reid
DMBT1, a regulator of mucosal homeostasis through the linking of mucosal defense and regeneration?
FEBS letters 2003;540(1-3):21-5.
2002: Weiqun Kang; Ole Nielsen; C Fenger; J Madsen; S Hansen; Ida Tornoe; Paul Eggleton; Kenneth B M Reid; Uffe Holmskov
The scavenger receptor, cysteine-rich domain-containing molecule gp-340 is differentially regulated in epithelial cell lines by phorbol ester.
Clinical and experimental immunology 2002;130(3):449-58.
2002: Soren Hansen; Dorte Holm; Vivi Moeller; Lars Vitved; Christian Bendixen; Kenneth B M Reid; Karsten Skjoedt; Uffe Holmskov
CL-46, a novel collectin highly expressed in bovine thymus and liver.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5726-34.
2002: Helena Kovacs; Sean I O'Ddonoghue; Hans Hoppe; David Comfort; Kenneth B M Reid; lain D Campbell; Michael Nilges
Solution structure of the coiled-coil trimerization domain from lung surfactant protein D.
Journal of biomolecular NMR 2002;24(2):89-102.
2002: Peter Strong; Kenneth B M Reid; Howard Clark
Intranasal delivery of a truncated recombinant human SP-D is effective at down-regulating allergic hypersensitivity in mice sensitized to allergens of Aspergillus fumigatus.
Clinical and experimental immunology 2002;130(1):19-24.
2002: Jinhua Lu; Cathleen Teh; Uday Kishore; Kenneth B M Reid
Collectins and ficolins: sugar pattern recognition molecules of the mammalian innate immune system.
Biochimica et biophysica acta 2002;1572(2-3):387-400.
2002: Howard Clark; Nades Palaniyar; Peter Strong; Jess Edmondson; Samuel Hawgood; Kenneth B M Reid
Surfactant protein D reduces alveolar macrophage apoptosis in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):2892-9.
2002: Howard Clark; Kenneth B M Reid
Structural requirements for SP-D function in vitro and in vivo: therapeutic potential of recombinant SP-D.
Immunobiology 2002;205(4-5):619-31.
2002: Uday Kishor; Taruna Madan; P Usha Sarma; Mamta Singh; Britta C Urban; Kenneth B M Reid
Protective roles of pulmonary surfactant proteins, SP-A and SP-D, against lung allergy and infection caused by Aspergillus fumigatus.
Immunobiology 2002;205(4-5):610-8.
2002: Nades Palaniyar; Jeya Nadesalingam; Kenneth B M Reid
Pulmonary innate immune proteins and receptors that interact with gram-positive bacterial ligands.
Immunobiology 2002;205(4-5):575-94.
2002: Uday Kishore; Mihaela S Kojouharova; Kenneth B M Reid
Recent progress in the understanding of the structure-function relationships of the globular head regions of C1q.
Immunobiology 2002;205(4-5):355-64.
2002: Kenneth B M Reid; Maurice G Colomb; Franz Petry; Michael Loos
Complement component C1 and the collectins--first-line defense molecules in innate and acquired immunity.
Trends in immunology 2002;23(3):115-7.
2002: Emma Murray; Wafa Khamri; Marjorie M Walker; Paul Eggleton; Anthony P Moran; John A Ferris; Susanne Knapp; Q Najma Karim; Mulugeta L Worku; Peter Strong; Kenneth B M Reid; Mark Thursz
Expression of surfactant protein D in the human gastric mucosa and during Helicobacter pylori infection.
Infection and immunity 2002;70(3):1481-7.
2001: Michael V Perdikoulis; Uday Kishore; Kenneth B M Reid
Expression and characterisation of the thrombospondin type I repeats of human properdin.
Biochimica et biophysica acta 2001;1548(2):265-77.
2001: Taruna Madan; Uday Kishore; M Singh; Peter Strong; E M Hussain; Kenneth B M Reid; P Usha Sarma
Protective role of lung surfactant protein D in a murine model of invasive pulmonary aspergillosis.
Infection and immunity 2001;69(4):2728-31.
2001: Taruna Madan; Uday Kishore; M Singh; Peter Strong; Howard Clark; E M Hussain; Kenneth B M Reid; P Usha Sarma
Surfactant proteins A and D protect mice against pulmonary hypersensitivity induced by Aspergillus fumigatus antigens and allergens.
The Journal of clinical investigation 2001;107(4):467-75.
2001: Uday Kishore; Kenneth B M Reid
Structures and functions of mammalian collectins.
Results and problems in cell differentiation 2001;33():225-48.
2001: Uday Kishore; Peter Strong; Michael V Perdikoulis; Kenneth B M Reid
A recombinant homotrimer, composed of the alpha helical neck region of human surfactant protein D and C1q B chain globular domain, is an inhibitor of the classical complement pathway.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):559-65.
2000: Uday Kishore; Kenneth B M Reid
C1q: structure, function, and receptors.
Immunopharmacology 2000;49(1-2):159-70.
2000: Paul Eggleton; A J Tenner; Kenneth B M Reid
C1q receptors.
Clinical and experimental immunology 2000;120(3):406-12.
2000: Paul Eggleton; Frank J Ward; Steven Johnson; MA Khamashta; GR Hughes; V A Hajela; Marek Michalak; EF Corbett; Norman A Staines; Kenneth B M Reid
Fine specificity of autoantibodies to calreticulin: epitope mapping and characterization.
Clinical and experimental immunology 2000;120(2):384-91.
2000: Howard W Clark; Kenneth B M Reid; Robert B Sim
Collectins and innate immunity in the lung.
Microbes and infection / Institut Pasteur 2000;2(3):273-8.
2000: PR Lawson; Kenneth B M Reid
A novel PCR-based technique using expressed sequence tags and gene homology for murine genetic mapping: localization of the complement genes.
International immunology 2000;12(3):231-40.
2000: PR Lawson; Kenneth B M Reid
The roles of surfactant proteins A and D in innate immunity.
Immunological reviews 2000;173():66-78.
2000: Martin van Eijk; Henk P Haagsman; T Skinner; A Archibald; Kenneth B M Reid; PR Lawson; A Archibold
Porcine lung surfactant protein D: complementary DNA cloning, chromosomal localization, and tissue distribution.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1442-50.
2000: P L Shah; David Hansell; PR Lawson; Kenneth B M Reid; C Morgan
Pulmonary alveolar proteinosis: clinical aspects and current concepts on pathogenesis.
Thorax 2000;55(1):67-77.
1999: Uffe Holmskov; Jan Mollenhauer; Jens Madsen; Lars Vitved; J Gronlund; Ida Tornoe; Anette Kliem; Kenneth B M Reid; Annemarie Poustka; Karsten Skjodt
Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(19):10794-9.
1999: Uday Kishore; Kenneth B M Reid
Modular organization of proteins containing C1q-like globular domain.
Immunopharmacology 1999;42(1-3):15-21.
1999: PR Lawson; V C Perkins; Uffe Holmskov; Kenneth B M Reid
Genomic organization of the mouse gene for lung surfactant protein D.
American journal of respiratory cell and molecular biology 1999;20(5):953-63.
1999: Paul Eggleton; Kenneth B M Reid
Lung surfactant proteins involved in innate immunity.
Current opinion in immunology 1999;11(1):28-33.
1999: Wilhelm J Schwaeble; Kenneth B M Reid
Does properdin crosslink the cellular and the humoral immune response?
Immunology today 1999;20(1):17-21.
1998: Helena Kovacs; Iain D Campbell; Peter Strong; Steven Johnson; Frank J Ward; Kenneth B M Reid; Paul Eggleton
Evidence that C1q binds specifically to CH2-like immunoglobulin gamma motifs present in the autoantigen calreticulin and interferes with complement activation.
Biochemistry 1998;37(51):17865-74.
1998: Kenneth B M Reid
Interactions of surfactant protein D with pathogens, allergens and phagocytes.
Biochimica et biophysica acta 1998;1408(2-3):290-5.
1998: Paul Eggleton; Kenneth B M Reid; A J Tenner
C1q--how many functions? How many receptors?
Trends in cell biology 1998;8(11):428-31.
1998: Peter Strong; Uday Kishore; C Morgan; A Lopez Bernal; M Singh; Kenneth B M Reid
A novel method of purifying lung surfactant proteins A and D from the lung lavage of alveolar proteinosis patients and from pooled amniotic fluid.
Journal of immunological methods 1998;220(1-2):139-49.
1998: Mihaela S Kojouharova; I D Panchev; Magdalena I Tchorbadjieva; Kenneth B M Reid; Hans Hoppe
Differential binding of IgG and of a HIV gp41 peptide by the B chain and A chain globular head sequences of C1q, respectively.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):4325-31.
1998: Kenneth B M Reid
Functional roles of the lung surfactant proteins SP-A and SP-D in innate immunity.
Immunobiology 1998;199(2):200-7.
1998: Jiu-Yao Wang; Chi-Chang Shieh; P F You; Huan-Yao Lei; Kenneth B M Reid
Inhibitory effect of pulmonary surfactant proteins A and D on allergen-induced lymphocyte proliferation and histamine release in children with asthma.
American journal of respiratory and critical care medicine 1998;158(2):510-8.
1998: Uday Kishore; LE Leigh; Paul Eggleton; Peter Strong; Michael V Perdikoulis; Antony C Willis; Kenneth B M Reid
Functional characterization of a recombinant form of the C-terminal, globular head region of the B-chain of human serum complement protein, C1q.
The Biochemical journal 1998;333 ( Pt 1)():27-32.
1998: LE Leigh; Berhane Ghebrehiwet; Timothy Perera; I N Bird; Peter Strong; Uday Kishore; Kenneth B M Reid; Paul Eggleton
C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signalling mechanisms.
The Biochemical journal 1998;330 ( Pt 1)():247-54.
1998: Kenneth B M Reid; Maurice G Colomb; Michael Loos
Complement component C1 and the collectins: parallels between routes of acquired and innate immunity.
Immunology today 1998;19(2):56-9.
1997: Nicholas J Lynch; Kenneth B M Reid; R H van den Berg; M R Daha; L A Leigh; Berhane Ghebrehiwet; W B Lim; Wilhelm J Schwaeble
Characterisation of the rat and mouse homologues of gC1qBP, a 33 kDa glycoprotein that binds to the globular 'heads' of C1q.
FEBS letters 1997;418(1-2):111-4.
1997: Taruna Madan; Uday Kishore; A Shah; Paul Eggleton; Peter Strong; J Y Wang; S S Aggrawal; P Usha Sarma; Kenneth B M Reid
Lung surfactant proteins A and D can inhibit specific IgE binding to the allergens of Aspergillus fumigatus and block allergen-induced histamine release from human basophils.
Clinical and experimental immunology 1997;110(2):241-9.
1997: Taruna Madan; Paul Eggleton; Uday Kishore; Peter Strong; S S Aggrawal; P Usha Sarma; Kenneth B M Reid
Binding of pulmonary surfactant proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages.
Infection and immunity 1997;65(8):3171-9.
1997: Berhane Ghebrehiwet; PD Lu; W Zhang; S A Keilbaugh; LE Leigh; Paul Eggleton; Kenneth B M Reid; Ellinor I B Peerschke
Evidence that the two C1q binding membrane proteins, gC1q-R and cC1q-R, associate to form a complex.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(3):1429-36.
1997: Uffe Holmskov; P Lawson; Børge Teisner; Ida Tornoe; A C Willis; C Morgan; Claus Koch; Kenneth B M Reid
Isolation and characterization of a new member of the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule.
The Journal of biological chemistry 1997;272(21):13743-9.
1997: Uday Kishore; RD Sontheimer; K N Sastry; E G Zappi; GR Hughes; MA Khamashta; Kenneth B M Reid; Paul Eggleton
The systemic lupus erythematosus (SLE) disease autoantigen-calreticulin can inhibit C1q association with immune complexes.
Clinical and experimental immunology 1997;108(2):181-90.
1997: Uday Kishore; RD Sontheimer; K N Sastry; K S Zaner; E G Zappi; GR Hughes; MA Khamashta; Peter Strong; Kenneth B M Reid; Paul Eggleton
Release of calreticulin from neutrophils may alter C1q-mediated immune functions.
The Biochemical journal 1997;322 ( Pt 2)():543-50.
1997: Paul Eggleton; Kenneth B M Reid; Uday Kishore; RD Sontheimer
Clinical relevance of calreticulin in systemic lupus erythematosus.
Lupus 1997;6(7):564-71.
1996: J Y Wang; Uday Kishore; Boon L Lim; Peter Strong; Kenneth B M Reid
Interaction of human lung surfactant proteins A and D with mite (Dermatophagoides pteronyssinus) allergens.
Clinical and experimental immunology 1996;106(2):367-73.
1996: Boon L Lim; Kenneth B M Reid; Berhane Ghebrehiwet; Ellinor I B Peerschke; L A Leigh; K T Preissner
The binding protein for globular heads of complement C1q, gC1qR. Functional expression and characterization as a novel vitronectin binding factor.
The Journal of biological chemistry 1996;271(43):26739-44.
1996: Berhane Ghebrehiwet; P D Lu; W Zhang; Boon L Lim; Paul Eggleton; L E Leigh; Kenneth B M Reid; Ellinor I B Peerschke
Identification of functional domains on gC1Q-R, a cell surface protein that binds to the globular "heads" of C1Q, using monoclonal antibodies and synthetic peptides.
Hybridoma 1996;15(5):333-42.
1996: Uday Kishore; J Y Wang; Hans Hoppe; Kenneth B M Reid
The alpha-helical neck region of human lung surfactant protein D is essential for the binding of the carbohydrate recognition domains to lipopolysaccharides and phospholipids.
The Biochemical journal 1996;318 ( Pt 2)():505-11.
1996: Kusumam Joseph; Berhane Ghebrehiwet; Ellinor I B Peerschke; Kenneth B M Reid; Allen P Kaplan
Identification of the zinc-dependent endothelial cell binding protein for high molecular weight kininogen and factor XII: identity with the receptor that binds to the globular "heads" of C1q (gC1q-R).
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8552-7.
1996: Kevan L Hartshorn; Kenneth B M Reid; Mitchell R White; J C Jensenius; S M Morris; Alfred I Tauber; Erika Crouch
Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies.
Blood 1996;87(8):3450-61.
1995: Jonathan M. G. Higgins; H Wiedemann; R Timpl; Kenneth B M Reid
Characterization of mutant forms of recombinant human properdin lacking single thrombospondin type I repeats. Identification of modules important for function.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(12):5777-85.
1995: J Y Wang; Uday Kishore; Kenneth B M Reid
A recombinant polypeptide, composed of the alpha-helical neck region and the carbohydrate recognition domain of conglutinin, self-associates to give a functionally intact homotrimer.
FEBS letters 1995;376(1-2):6-10.
1995: Berhane Ghebrehiwet; Richard R Kew; Barry L Gruber; Mary J Marchese; Ellinor I B Peerschke; Kenneth B M Reid
Murine mast cells express two types of C1q receptors that are involved in the induction of chemotaxis and chemokinesis.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(5):2614-9.
1995: Paul Eggleton; Berhane Ghebrehiwet; K N Sastry; J P Coburn; K S Zaner; Kenneth B M Reid; Alfred I Tauber
Identification of a gC1q-binding protein (gC1q-R) on the surface of human neutrophils. Subcellular localization and binding properties in comparison with the cC1q-R.
The Journal of clinical investigation 1995;95(4):1569-78.
1995: Uffe Holmskov; Steen B Laursen; R Malhotra; H Wiedemann; R Timpl; G R Stuart; Ida Tornøe; P S Madsen; Kenneth B M Reid; Jens C Jensenius
Comparative study of the structural and functional properties of a bovine plasma C-type lectin, collectin-43, with other collectins.
The Biochemical journal 1995;305 ( Pt 3)():889-96.
1994: Boon L Lim; J Y Wang; Uffe Holmskov; Hans Hoppe; Kenneth B M Reid
Expression of the carbohydrate recognition domain of lung surfactant protein D and demonstration of its binding to lipopolysaccharides of gram-negative bacteria.
Biochemical and biophysical research communications 1994;202(3):1674-80.
1994: Ellinor I B Peerschke; Kenneth B M Reid; Berhane Ghebrehiwet
Identification of a novel 33-kDa C1q-binding site on human blood platelets.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(12):5896-901.
1994: Berhane Ghebrehiwet; Boon L Lim; Ellinor I B Peerschke; Antony C Willis; Kenneth B M Reid
Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q.
The Journal of experimental medicine 1994;179(6):1809-21.
1994: Hans Hoppe; Paul N Barlow; Kenneth B M Reid
A parallel three stranded alpha-helical bundle at the nucleation site of collagen triple-helix formation.
FEBS letters 1994;344(2-3):191-5.
1994: K Miyamura; L E Leigh; J Lu; J Hopkin; Andrés López Bernal; Kenneth B M Reid
Surfactant protein D binding to alveolar macrophages.
The Biochemical journal 1994;300 ( Pt 1)():237-42.
1994: Boon L Lim; Antony C Willis; Kenneth B M Reid; J Lu; Steen B Laursen; Jens C Jensenius; Uffe Holmskov
Primary structure of bovine collectin-43 (CL-43). Comparison with conglutinin and lung surfactant protein-D.
The Journal of biological chemistry 1994;269(16):11820-4.
1994: Wilhelm J Schwaeble; Hartwig P Huemer; Johannes Möst; M P Dierich; M Ströbel; C Claus; Kenneth B M Reid; H W Ziegler-Heitbrock
Expression of properdin in human monocytes.
European journal of biochemistry / FEBS 1994;219(3):759-64.
1994: K Miyamura; R Malhotra; Hans Hoppe; Kenneth B M Reid; P J Phizackerley; P Macpherson; Andrés López Bernal
Surfactant proteins A (SP-A) and D (SP-D): levels in human amniotic fluid and localization in the fetal membranes.
Biochimica et biophysica acta 1994;1210(3):303-7.
1994: Kenneth B M Reid; M W Turner
Mammalian lectins in activation and clearance mechanisms involving the complement system.
Springer seminars in immunopathology 1994;15(4):307-26.
1993: K Kölble; Kenneth B M Reid
The genomics of soluble proteins with collagenous domains: C1q, MBL, SP-A, SP-D, conglutinin, and CL-43.
Behring Institute Mitteilungen 1993;(93):81-6.
1993: J Lu; H Wiedemann; R Timpl; Kenneth B M Reid
Similarity in structure between C1q and the collectins as judged by electron microscopy.
Behring Institute Mitteilungen 1993;(93):6-16.
1993: K Kölble; J Lu; S E Mole; S Kaluz; Kenneth B M Reid
Assignment of the human pulmonary surfactant protein D gene (SFTP4) to 10q22-q23 close to the surfactant protein A gene cluster.
Genomics 1993;17(2):294-8.
1993: J Lu; H Wiedemann; Uffe Holmskov; Steffen Thiel; R Timpl; Kenneth B M Reid
Structural similarity between lung surfactant protein D and conglutinin. Two distinct, C-type lectins containing collagen-like sequences.
European journal of biochemistry / FEBS 1993;215(3):793-9.
1993: Uffe Holmskov; Børge Teisner; Antony C Willis; Kenneth B M Reid; Jens C Jensenius
Purification and characterization of a bovine serum lectin (CL-43) with structural homology to conglutinin and SP-D and carbohydrate specificity similar to mannan-binding protein.
The Journal of biological chemistry 1993;268(14):10120-5.
1993: J Lu; Steen B Laursen; Steffen Thiel; Jens C Jensenius; Kenneth B M Reid
The cDNA cloning of conglutinin and identification of liver as a primary site of synthesis of conglutinin in members of the Bovidae.
The Biochemical journal 1993;292 ( Pt 1)():157-62.
1993: Kenneth B M Reid
Structure/function relationships in the collectins (mammalian lectins containing collagen-like regions).
Biochemical Society transactions 1993;21(2):464-8.
1993: Uffe Holmskov; P Holt; Kenneth B M Reid; Antony C Willis; Børge Teisner; Jens C Jensenius
Purification and characterization of bovine mannan-binding protein.
Glycobiology 1993;3(2):147-53.
1993: E I Peerschke; R Malhotra; Berhane Ghebrehiwet; Kenneth B M Reid; Antony C Willis; Robert B Sim
Isolation of a human endothelial cell C1q receptor (C1qR).
Journal of leukocyte biology 1993;53(2):179-84.
1993: Boon L Lim; J Lu; Kenneth B M Reid
Structural similarity between bovine conglutinin and bovine lung surfactant protein D and demonstration of liver as a site of synthesis of conglutinin.
Immunology 1993;78(1):159-65.
1993: K Kölble; A J Cant; A C Fay; K Whaley; M Schlesinger; Kenneth B M Reid
Carrier detection in families with properdin deficiency by microsatellite haplotyping.
The Journal of clinical investigation 1993;91(1):99-102.
1993: K Kölble; Kenneth B M Reid
Genetic deficiencies of the complement system and association with disease--early components.
International reviews of immunology 1993;10(1):17-36.
1993: Kathleen F Nolan; Kenneth B M Reid
Properdin.
Methods in enzymology 1993;223():35-46.
1993: Kenneth B M Reid; Kathleen F Nolan; H R Lijnen; D Collen
Proteolytic enzymes in coagulation, fibrinolysis, and complement activation. Introduction.
Methods in enzymology 1993;223():1-9.
1992: Kathleen F Nolan; S Kaluz; Jonathan M. G. Higgins; D Goundis; Kenneth B M Reid
Characterization of the human properdin gene.
The Biochemical journal 1992;287 ( Pt 1)():291-7.
1992: S Kaluz; K Kölble; Kenneth B M Reid
Directional cloning of PCR products using exonuclease III.
Nucleic acids research 1992;20(16):4369-70.
1992: J Lu; Antony C Willis; Kenneth B M Reid
Purification, characterization and cDNA cloning of human lung surfactant protein D.
The Biochemical journal 1992;284 ( Pt 3)():795-802.
1991: Robert B Sim; Kenneth B M Reid
C1: molecular interactions with activating systems.
Immunology today 1991;12(9):307-11.
1991: S Kaluz; Kenneth B M Reid
A novel rapid method for detection of PCR products.
Nucleic acids research 1991;19(14):4012.
1991: Kathleen F Nolan; Wilhelm J Schwaeble; S Kaluz; M P Dierich; Kenneth B M Reid
Molecular cloning of the cDNA coding for properdin, a positive regulator of the alternative pathway of human complement.
European journal of immunology 1991;21(3):771-6.
1991: G C Sellar; Derek J Blake; Kenneth B M Reid
Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q.
The Biochemical journal 1991;274 ( Pt 2)():481-90.
1990: Kathleen F Nolan; Kenneth B M Reid
Complete primary structure of human properdin: a positive regulator of the alternative pathway of the serum complement system.
Biochemical Society transactions 1990;18(6):1161-2.
1990: R Malhotra; Robert B Sim; Kenneth B M Reid
Interaction of C1q, and other proteins containing collagen-like domains, with the C1q receptor.
Biochemical Society transactions 1990;18(6):1145-8.
1990: E P Evans; M D Burtenshaw; S H Laval; D Goundis; Kenneth B M Reid; Y Boyd
Localization of the properdin factor complement locus Pfc to band A3 on the mouse X chromosome.
Genetical research 1990;56(2-3):153-5.
1990: R Malhotra; Steffen Thiel; Kenneth B M Reid; Robert B Sim
Human leukocyte C1q receptor binds other soluble proteins with collagen domains.
The Journal of experimental medicine 1990;172(3):955-9.
1990: J H Lu; Steffen Thiel; H Wiedemann; R Timpl; Kenneth B M Reid
Binding of the pentamer/hexamer forms of mannan-binding protein to zymosan activates the proenzyme C1r2C1s2 complex, of the classical pathway of complement, without involvement of C1q.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(6):2287-94.
1989: G J Cooper; Anthony J Day; Antony C Willis; A N Roberts; Kenneth B M Reid; Brendan Leighton
Amylin and the amylin gene: structure, function and relationship to islet amyloid and to diabetes mellitus.
Biochimica et biophysica acta 1989;1014(3):247-58.
1989: Kenneth B M Reid
Chemistry and molecular genetics of C1q.
Behring Institute Mitteilungen 1989;(84):8-19.
1989: D Goundis; S M Holt; Y Boyd; Kenneth B M Reid
Localization of the properdin structural locus to Xp11.23-Xp21.1.
Genomics 1989;5(1):56-60.
1989: Kenneth B M Reid
Deficiency of the first component of human complement.
Immunodeficiency reviews 1989;1(3):247-60.
1988: A Erdei; Kenneth B M Reid
Characterization of C1q-binding material released from the membranes of Raji and U937 cells by limited proteolysis with trypsin.
The Biochemical journal 1988;255(2):493-9.
1988: G J Cooper; Brendan Leighton; G Dimitriadis; M Parry-Billings; J M Kowalchuk; K Howland; J B Rothbard; A C Willis; Kenneth B M Reid
Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7763-6.
1988: D Goundis; Kenneth B M Reid
Properdin, the terminal complement components, thrombospondin and the circumsporozoite protein of malaria parasites contain similar sequence motifs.
Nature 1988;335(6185):82-5.
1988: Berhane Ghebrehiwet; S Bossone; A Erdei; Kenneth B M Reid
Reversible biotinylation of C1q with a cleavable biotinyl derivative. Application in C1q receptor (C1qR) purification.
Journal of immunological methods 1988;110(2):251-60.
1988: S J Lintin; A R Lewin; Kenneth B M Reid
Derivation of the sequence of the signal peptide in human C4b-binding protein and interspecies cross-hybridisation of the C4bp cDNA sequence.
FEBS letters 1988;232(2):328-32.
1988: L Hsiung; Alister W Dodds; D W Mason; Kenneth B M Reid
A monoclonal antibody to C1q which appears to interact with C1r2C1s2-binding site.
FEBS letters 1988;229(1):21-4.
1988: R Duncan Campbell; S K Alex Law; Kenneth B M Reid; Robert B Sim
Structure, organization, and regulation of the complement genes.
Annual review of immunology 1988;6():161-95.
1988: R A McAdam; D Goundis; Kenneth B M Reid
A homozygous point mutation results in a stop codon in the C1q B-chain of a C1q-deficient individual.
Immunogenetics 1988;27(4):259-64.
1987: G J Cooper; A C Willis; Anne Clark; R C Turner; Robert B Sim; Kenneth B M Reid
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8628-32.
1987: G J Cooper; A C Willis; Kenneth B M Reid; A Clark; C A Baker; R C Turner; C E Lewis; J F Morris; K Howland; J B Rothbard
Diabetes-associated peptide.
Lancet 1987;2(8565):966.