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Ralph Reisfeld
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40
Xiang, Rong
29
Lode, Holger
25
Gillies, Stephen
19
Luo, Yunping
15
Niethammer, Andreas
15
Becker, Jürgen
15
Zhou, He
11
Dolman, Carrie
10
Pertl, Ursula
10
Varki, NM
9
Montgomery, Anthony
8
Sondel, Paul
7
Ruehlmann, Michael
7
Mizutani, Masato
7
Mizutani, Noriko
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All Publications
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2009: Hauer Arnaud D; Habets Kim L L; van Wanrooij Eva J A; de Vos Paula; Krueger Joerg; Reisfeld Ralph A; van Berkel Theo J C; Kuiper Johan
Vaccination against TIE2 reduces atherosclerosis.
Atherosclerosis 2009;204(2):365-71.
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2008: Johnson Erik E; Lum Hillary D; Rakhmilevich Alexander L; Schmidt Brian E; Furlong Meghan; Buhtoiarov Ilia N; Hank Jacquelyn A; Raubitschek Andrew; Colcher David; Reisfeld Ralph A; Gillies Stephen D; Sondel Paul M
Intratumoral immunocytokine treatment results in enhanced antitumor effects.
Cancer immunology, immunotherapy : CII 2008;57(12):1891-902.
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2008: Xiang Rong; Luo Yunping; Niethammer Andreas G; Reisfeld Ralph A
Oral DNA vaccines target the tumor vasculature and microenvironment and suppress tumor growth and metastasis.
Immunological reviews 2008;222():117-28.
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2008: Lewen Susanna; Zhou He; Hu Huai-dong; Cheng Tingmei; Markowitz Dorothy; Reisfeld Ralph A; Xiang Rong; Luo Yunping
A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis.
Cancer immunology, immunotherapy : CII 2008;57(4):507-15.
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2008: Schrama David; Voigt Heike; Eggert Andreas O; Xiang Rong; Zhou He; Schumacher Ton N M; Andersen Mads H; thor Straten Per; Reisfeld Ralph A; Becker Jürgen C
Immunological tumor destruction in a murine melanoma model by targeted LTalpha independent of secondary lymphoid tissue.
Cancer immunology, immunotherapy : CII 2008;57(1):85-95.
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2007: Hauer Arnaud D; van Puijvelde Gijs H M; Peterse Niels; de Vos Paula; van Weel Vincent; van Wanrooij Eva J A; Biessen Erik A L; Quax Paul H A; Niethammer Andreas G; Reisfeld Ralph A; van Berkel Theo J C; Kuiper Johan
Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(9):2050-7.
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2007: Raja Chand; Graham Peter; Abbas Rizvi Syed M; Song Emma; Goldsmith Helen; Thompson John; Bosserhoff Anja; Morgenstern Alfred; Apostolidis Christos; Kearsley John; Reisfeld Ralph; Allen Barry J
Interim analysis of toxicity and response in phase 1 trial of systemic targeted alpha therapy for metastatic melanoma.
Cancer biology & therapy 2007;6(6):846-52.
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2007: Petrovan Ramona J; Kaplan Charles D; Reisfeld Ralph A; Curtiss Linda K
DNA vaccination against VEGF receptor 2 reduces atherosclerosis in LDL receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(5):1095-100.
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2007: Zeng Yan; Huebener Nicole; Fest Stefan; Weixler Silke; Schroeder Ulrike; Gaedicke Gerhard; Xiang Rong; Schramm Alexander; Eggert Angelika; Reisfeld Ralph A; Lode Holger N
Fractalkine (CX3CL1)- and interleukin-2-enriched neuroblastoma microenvironment induces eradication of metastases mediated by T cells and natural killer cells.
Cancer research 2007;67(5):2331-8.
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2007: Luo Yunping; Markowitz Dorothy; Xiang Rong; Zhou He; Reisfeld Ralph A
FLK-1-based minigene vaccines induce T cell-mediated suppression of angiogenesis and tumor protective immunity in syngeneic BALB/c mice.
Vaccine 2007;25(8):1409-15.
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2006: Li Jiali; Lad Sonya; Yang Guang; Luo Yunping; Iacobelli-Martinez Milena; Primus F James; Reisfeld Ralph A; Li Erguang
Adenovirus fiber shaft contains a trimerization element that supports peptide fusion for targeted gene delivery.
Journal of virology 2006;80(24):12324-31.
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2006: Kruger Jorg A; Kaplan Charles D; Luo Yunping; Zhou He; Markowitz Dorothy; Xiang Rong; Reisfeld Ralph A
Characterization of stem cell-like cancer cells in immune-competent mice.
Blood 2006;108(12):3906-12.
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2006: Lee Sung-Hyung; Mizutani Noriko; Mizutani Masato; Luo Yunping; Zhou He; Kaplan Charles; Kim Sung-Woo; Xiang Rong; Reisfeld Ralph A
Endoglin (CD105) is a target for an oral DNA vaccine against breast cancer.
Cancer immunology, immunotherapy : CII 2006;55(12):1565-74.
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2006: Kaplan Charles D; Krüger Jörg A; Zhou He; Luo Yunping; Xiang Rong; Reisfeld Ralph A
A novel DNA vaccine encoding PDGFRbeta suppresses growth and dissemination of murine colon, lung and breast carcinoma.
Vaccine 2006;24(47-48):6994-7002.
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2006: Kim Bumseok; Suvas Susmit; Sarangi Pranita P; Lee Sujin; Reisfeld Ralph A; Rouse Barry T
Vascular endothelial growth factor receptor 2-based DNA immunization delays development of herpetic stromal keratitis by antiangiogenic effects.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):4122-31.
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2006: Luo Yunping; Zhou He; Krueger Jörg; Kaplan Charles; Lee Sung-Hyung; Dolman Carrie; Markowitz Dorothy; Wu Wenyuan; Liu Cheng; Reisfeld Ralph A; Xiang Rong
Targeting tumor-associated macrophages as a novel strategy against breast cancer.
The Journal of clinical investigation 2006;116(8):2132-2141.
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2006: Loeffler Markus; Krüger Jörg A; Niethammer Andreas G; Reisfeld Ralph A
Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake.
The Journal of clinical investigation 2006;116(7):1955-62.
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2006: Mahanivong Chitladda; Krüger Jörg A; Bian Dafang; Reisfeld Ralph A; Huang Shuang
A simplified cloning strategy for the generation of an endothelial cell selective recombinant adenovirus vector.
Journal of virological methods 2006;135(1):127-35.
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2006: Schrama David; Voigt Heike; Eggert Andreas O; Xiang Rong; Reisfeld Ralph A; Becker Jürgen C
Therapeutic efficacy of tumor-targeted IL2 in LTalpha(-/-) mice depends on conditioned T cells.
Cancer immunology, immunotherapy : CII 2006;55(7):861-6.
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2006: Zhou He; Luo Yunping; Kaplan Charles D; Krüger Jörg A; Lee Sung-Hyung; Xiang Rong; Reisfeld Ralph A
A DNA-based cancer vaccine enhances lymphocyte cross talk by engaging the NKG2D receptor.
Blood 2006;107(8):3251-7.
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2006: Osenga Kaci L; Hank Jacquelyn A; Albertini Mark R; Gan Jacek; Sternberg Adam G; Eickhoff Jens; Seeger Robert C; Matthay Katherine K; Reynolds C Patrick; Twist Clare; Krailo Mark; Adamson Peter C; Reisfeld Ralph A; Gillies Stephen D; Sondel Paul M;
A phase I clinical trial of the hu14.18-IL2 (EMD 273063) as a treatment for children with refractory or recurrent neuroblastoma and melanoma: a study of the Children's Oncology Group.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1750-9.
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2006: Schrama David; Reisfeld Ralph A; Becker Jürgen C
Antibody targeted drugs as cancer therapeutics.
Nature reviews. Drug discovery 2006;5(2):147-59.
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2006: Wu Wenyuan; Luo Yunping; Sun Chengzao; Liu Yuan; Kuo Paul; Varga Janos; Xiang Rong; Reisfeld Ralph; Janda Kim D; Edgington Thomas S; Liu Cheng
Targeting cell-impermeable prodrug activation to tumor microenvironment eradicates multiple drug-resistant neoplasms.
Cancer research 2006;66(2):970-80.
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2005: Allen Barry J; Raja Chand; Rizvi Syed; Li Yong; Tsui Wendy; Graham Peter; Thompson John F; Reisfeld Ralph A; Kearsley John
Intralesional targeted alpha therapy for metastatic melanoma.
Cancer biology & therapy 2005;4(12):1318-24.
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2005: Abdollahi Amir; Griggs David W; Zieher Heike; Roth Alexandra; Lipson Kenneth E; Saffrich Rainer; Gröne Hermann-Josef; Hallahan Dennis E; Reisfeld Ralph A; Debus Juergen; Niethammer Andreas G; Huber Peter E
Inhibition of alpha(v)beta3 integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(17):6270-9.
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2005: Zhou He; Luo Yunping; Mizutani Masato; Mizutani Noriko; Reisfeld Ralph A; Xiang Rong
T cell-mediated suppression of angiogenesis results in tumor protective immunity.
Blood 2005;106(6):2026-32.
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2005: Zhou He; Luo Yunping; Lo Jeng-fan; Kaplan Charles D; Mizutani Masato; Mizutani Noriko; Lee Jiing-Dwan; Primus F James; Becker Jürgen C; Xiang Rong; Reisfeld Ralph A
DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the NKG2D receptor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):10846-51.
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2005: Loeffler Markus; Krüger Jörg A; Reisfeld Ralph A
Immunostimulatory effects of low-dose cyclophosphamide are controlled by inducible nitric oxide synthase.
Cancer research 2005;65(12):5027-30.
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2005: Lo Jeng-Fan; Zhou He; Fearns Colleen; Reisfeld Ralph A; Yang Young; Lee Jiing-Dwan
Tid1 is required for T cell transition from double-negative 3 to double-positive stages.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(10):6105-12.
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2005: Luo Yunping; Zhou He; Mizutani Masato; Mizutani Noriko; Liu Cheng; Xiang Rong; Reisfeld Ralph A
A DNA vaccine targeting Fos-related antigen 1 enhanced by IL-18 induces long-lived T-cell memory against tumor recurrence.
Cancer research 2005;65(8):3419-27.
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2005: Xiang Rong; Mizutani Noriko; Luo Yunping; Chiodoni Claudia; Zhou He; Mizutani Masato; Ba Yi; Becker Juergen C; Reisfeld Ralph A
A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication.
Cancer research 2005;65(2):553-61.
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2005: Niethammer Andreas G; Wodrich Harald; Loeffler Markus; Lode Holger N; Emmerich Kathrin; Abdollahi Amir; Krempien Robert; Debus Juergen; Huber Peter E; Reisfeld Ralph A
Multidrug resistance-1 (MDR-1): a new target for T cell-based immunotherapy.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(1):158-9.
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2004: King David M; Albertini Mark R; Schalch Heidi; Hank Jacquelyn A; Gan Jacek; Surfus Jean; Mahvi David; Schiller Joan H; Warner Thomas; Kim KyungMann; Eickhoff Jens; Kendra Kari; Reisfeld Ralph; Gillies Stephen D; Sondel Paul
Phase I clinical trial of the immunocytokine EMD 273063 in melanoma patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(22):4463-73.
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2004: Neal Zane C; Yang Jeannie C; Rakhmilevich Alexander L; Buhtoiarov Ilia N; Lum Hillary E; Imboden Michael; Hank Jacquelyn A; Lode Holger N; Reisfeld Ralph A; Gillies Stephen D; Sondel Paul M
Enhanced activity of hu14.18-IL2 immunocytokine against murine NXS2 neuroblastoma when combined with interleukin 2 therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4839-47.
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2004: Reisfeld Ralph A; Niethammer Andreas G; Luo Yunping; Xiang Rong
DNA vaccines suppress tumor growth and metastases by the induction of anti-angiogenesis.
Immunological reviews 2004;199():181-90.
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2004: Zhou He; Luo Yunping; Mizutani Masato; Mizutani Noriko; Becker Jürgen C; Primus F James; Xiang Rong; Reisfeld Ralph A
A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines.
The Journal of clinical investigation 2004;113(12):1792-8.
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2004: Reisfeld Ralph A; Niethammer A G; Luo Y; Xiang R
DNA vaccines designed to inhibit tumor growth by suppression of angiogenesis.
International archives of allergy and immunology 2004;133(3):295-304.
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2004: Neal Zane C; Imboden Michael; Rakhmilevich Alexander L; Kim Kyung-Mann; Hank Jacquelyn A; Surfus Jean; Dixon John R; Lode Holger N; Reisfeld Ralph A; Gillies Stephen D; Sondel Paul M
NXS2 murine neuroblastomas express increased levels of MHC class I antigens upon recurrence following NK-dependent immunotherapy.
Cancer immunology, immunotherapy : CII 2004;53(1):41-52.
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2003: Luo Yunping; Zhou He; Mizutani Masato; Mizutani Noriko; Reisfeld Ralph A; Xiang Rong
Transcription factor Fos-related antigen 1 is an effective target for a breast cancer vaccine.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8850-5.
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2003: Schroeder Ulrike; Bernt Kathrin M; Lange Björn; Wenkel Jens; Jikai Jiang; Shabat Doron; Amir Roey; Huebener Nicole; Niethammer Andreas G; Hagemeier Christian; Wiebusch Lüder; Gaedicke Gerhard; Wrasidlo Wolfgang; Reisfeld Ralph A; Lode Holger N
Hydrolytically activated etoposide prodrugs inhibit MDR-1 function and eradicate established MDR-1 multidrug-resistant T-cell leukemia.
Blood 2003;102(1):246-53.
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2003: Luo Yunping; O'Hagan Derek; Zhou He; Singh Manmohan; Ulmer Jeffrey; Reisfeld Ralph A; James Primus F; Xiang Rong
Plasmid DNA encoding human carcinoembryonic antigen (CEA) adsorbed onto cationic microparticles induces protective immunity against colon cancer in CEA-transgenic mice.
Vaccine 2003;21(17-18):1938-47.
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2003: Reisfeld Ralph A
Preface.
Cancer immunology, immunotherapy : CII 2003;52(5):255-6.
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2003: Pertl Ursula; Wodrich Harald; Ruehlmann J Michael; Gillies Stephen D; Lode Holger N; Reisfeld Ralph A
Immunotherapy with a posttranscriptionally modified DNA vaccine induces complete protection against metastatic neuroblastoma.
Blood 2003;101(2):649-54.
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2002: Niethammer Andreas G; Xiang Rong; Becker Jürgen C; Wodrich Harald; Pertl Ursula; Karsten Gabriele; Eliceiri Brian P; Reisfeld Ralph A
A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth.
Nature medicine 2002;8(12):1369-75.
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2002: Wrasidlo Wolfgang; Gaedicke Gerhard; Guy Rodney Kiplin; Renaud Johanne; Pitsinos Emmanuel; Nicolaou Kyriaco C; Reisfeld Ralph A; Lode Holger N
A novel 2'-(N-methylpyridinium acetate) prodrug of paclitaxel induces superior antitumor responses in preclinical cancer models.
Bioconjugate chemistry 2002;13(5):1093-9.
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2002: Dummer Wolfgang; Niethammer Andreas G; Baccala Roberto; Lawson Brian R; Wagner Norbert; Reisfeld Ralph A; Theofilopoulos Argyrios N
T cell homeostatic proliferation elicits effective antitumor autoimmunity.
The Journal of clinical investigation 2002;110(2):185-92.
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2002: Hood John D; Bednarski Mark; Frausto Ricardo; Guccione Samira; Reisfeld Ralph A; Xiang Rong; Cheresh David A
Tumor regression by targeted gene delivery to the neovasculature.
Science (New York, N.Y.) 2002;296(5577):2404-7.
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2002: Schrama David; Straten Per thor; Bröcker Eva-Bettina; Reisfeld Ralph A; Becker Jürgen C
Cytokine fusion protein treatment.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2002;160():185-94.
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2001: Ruehlmann J M; Xiang R; Niethammer A G; Ba Y; Pertl U; Dolman C S; Gillies S D; Reisfeld R A
MIG (CXCL9) chemokine gene therapy combines with antibody-cytokine fusion protein to suppress growth and dissemination of murine colon carcinoma.
Cancer research 2001;61(23):8498-503.
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2001: Niethammer A G; Primus F J; Xiang R; Dolman C S; Ruehlmann J M; Ba Y; Gillies S D; Reisfeld R A
An oral DNA vaccine against human carcinoembryonic antigen (CEA) prevents growth and dissemination of Lewis lung carcinoma in CEA transgenic mice.
Vaccine 2001;20(3-4):421-9.
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2001: Xiang R; Primus F J; Ruehlmann J M; Niethammer A G; Silletti S; Lode H N; Dolman C S; Gillies S D; Reisfeld R A
A dual-function DNA vaccine encoding carcinoembryonic antigen and CD40 ligand trimer induces T cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4560-5.
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2001: Niethammer A G; Xiang R; Ruehlmann J M; Lode H N; Dolman C S; Gillies S D; Reisfeld R A
Targeted interleukin 2 therapy enhances protective immunity induced by an autologous oral DNA vaccine against murine melanoma.
Cancer research 2001;61(16):6178-84.
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2001: Shabat D; Lode H N; Pertl U; Reisfeld R A; Rader C; Lerner R A; Barbas C F
In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7528-33.
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2001: Pertl U; Luster A D; Varki N M; Homann D; Gaedicke G; Reisfeld R A; Lode H N
IFN-gamma-inducible protein-10 is essential for the generation of a protective tumor-specific CD8 T cell response induced by single-chain IL-12 gene therapy.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(11):6944-51.
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2001: Xiang R; Silletti S; Lode H N; Dolman C S; Ruehlmann J M; Niethammer A G; Pertl U; Gillies S D; Primus F J; Reisfeld R A
Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):856s-864s.
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2001: Imboden M; Murphy K R; Rakhmilevich A L; Neal Z C; Xiang R; Reisfeld R A; Gillies S D; Sondel P M
The level of MHC class I expression on murine adenocarcinoma can change the antitumor effector mechanism of immunocytokine therapy.
Cancer research 2001;61(4):1500-7.
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2001: Schrama D; thor Straten P; Fischer W H; McLellan A D; Bröcker E B; Reisfeld R A; Becker J C
Targeting of lymphotoxin-alpha to the tumor elicits an efficient immune response associated with induction of peripheral lymphoid-like tissue.
Immunity 2001;14(2):111-21.
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2000: Lode H N; Pertl U; Xiang R; Gaedicke G; Reisfeld R A
Tyrosine hydroxylase-based DNA-vaccination is effective against murine neuroblastoma.
Medical and pediatric oncology 2000;35(6):641-6.
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2000: Balicki D; Reisfeld R A; Pertl U; Beutler E; Lode H N
Histone H2A-mediated transient cytokine gene delivery induces efficient antitumor responses in murine neuroblastoma.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11500-4.
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2000: Lode H N; Xiang R; Pertl U; Förster E; Schoenberger S P; Gillies S D; Reisfeld R A
Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction.
The Journal of clinical investigation 2000;105(11):1623-30.
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2000: Lode H N; Xiang R; Perri P; Pertl U; Lode A; Gillies S D; Reisfeld R A
What to do with targeted IL-2.
Drugs of today (Barcelona, Spain : 1998) 2000;36(5):321-36.
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2000: Lode H N; Xiang R; Gillies S D; Reisfeld R A
Amplification of T cell-mediated immune responses by antibody-cytokine fusion proteins.
Immunological investigations 2000;29(2):117-20.
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2000: Xiang R; Lode H N; Chao T H; Ruehlmann J M; Dolman C S; Rodriguez F; Whitton J L; Overwijk W W; Restifo N P; Reisfeld R A
An autologous oral DNA vaccine protects against murine melanoma.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5492-7.
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1999: Nayeem N; Silletti S; Yang X; Lemmon V P; Reisfeld R A; Stallcup W B; Montgomery A M
A potential role for the plasmin(ogen) system in the posttranslational cleavage of the neural cell adhesion molecule L1.
Journal of cell science 1999;112 ( Pt 24)():4739-49.
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1999: Xiang R; Lode H N; Gillies S D; Reisfeld R A
T cell memory against colon carcinoma is long-lived in the absence of antigen.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(7):3676-83.
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1999: Lode H N; Xiang R; Duncan S R; Theofilopoulos A N; Gillies S D; Reisfeld R A
Tumor-targeted IL-2 amplifies T cell-mediated immune response induced by gene therapy with single-chain IL-12.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8591-6.
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1999: Lode H N; Moehler T; Xiang R; Jonczyk A; Gillies S D; Cheresh D A; Reisfeld R A
Synergy between an antiangiogenic integrin alphav antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1591-6.
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1998: Dolman C S; Mueller B M; Lode H N; Xiang R; Gillies S D; Reisfeld R A
Suppression of human prostate carcinoma metastases in severe combined immunodeficient mice by interleukin 2 immunocytokine therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2551-7.
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1998: Xiang R; Lode H N; Dreier T; Gillies S D; Reisfeld R A
Induction of persistent tumor-protective immunity in mice cured of established colon carcinoma metastases.
Cancer research 1998;58(17):3918-25.
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1998: Lode H N; Reisfeld R A; Handgretinger R; Nicolaou K C; Gaedicke G; Wrasidlo W
Targeted therapy with a novel enediyene antibiotic calicheamicin theta(I)1 effectively suppresses growth and dissemination of liver metastases in a syngeneic model of murine neuroblastoma.
Cancer research 1998;58(14):2925-8.
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1998: Dreier T; Lode H N; Xiang R; Dolman C S; Reisfeld R A; Kang A S
Recombinant immunocytokines targeting the mouse transferrin receptor: construction and biological activities.
Bioconjugate chemistry 1998;9(4):482-9.
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1998: Gillies S D; Lan Y; Wesolowski J S; Qian X; Reisfeld R A; Holden S; Super M; Lo K M
Antibody-IL-12 fusion proteins are effective in SCID mouse models of prostate and colon carcinoma metastases.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):6195-203.
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1998: Lode H N; Dreier T; Xiang R; Varki N M; Kang A S; Reisfeld R A
Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2475-80.
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1998: Lode H N; Xiang R; Dreier T; Varki N M; Gillies S D; Reisfeld R A
Natural killer cell-mediated eradication of neuroblastoma metastases to bone marrow by targeted interleukin-2 therapy.
Blood 1998;91(5):1706-15.
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1997: Lode H N; Xiang R; Varki N M; Dolman C S; Gillies S D; Reisfeld R A
Targeted interleukin-2 therapy for spontaneous neuroblastoma metastases to bone marrow.
Journal of the National Cancer Institute 1997;89(21):1586-94.
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1997: Xiang R; Lode H N; Dolman C S; Dreier T; Varki N M; Qian X; Lo K M; Lan Y; Super M; Gillies S D; Reisfeld R A
Elimination of established murine colon carcinoma metastases by antibody-interleukin 2 fusion protein therapy.
Cancer research 1997;57(21):4948-55.
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1997: Albertini M R; Hank J A; Schiller J H; Khorsand M; Borchert A A; Gan J; Bechhofer R; Storer B; Reisfeld R A; Sondel P M
Phase IB trial of chimeric antidisialoganglioside antibody plus interleukin 2 for melanoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(8):1277-88.
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1997: Reisfeld R A; Becker J C; Gillies S D
Immunocytokines: a new approach to immunotherapy of melanoma.
Melanoma research 1997;7 Suppl 2():S99-106.
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1997: Frost J D; Hank J A; Reaman G H; Frierdich S; Seeger R C; Gan J; Anderson P M; Ettinger L J; Cairo M S; Blazar B R; Krailo M D; Matthay K K; Reisfeld R A; Sondel P M
A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group.
Cancer 1997;80(2):317-33.
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1997: Pancook J D; Reisfeld R A; Varki N; Vitiello A; Fox R I; Montgomery A M
Expression and regulation of the neural cell adhesion molecule L1 on human cells of myelomonocytic and lymphoid origin.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(9):4413-21.
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1997: DeClerck Y A; Imren S; Montgomery A M; Mueller B M; Reisfeld R A; Laug W E
Proteases and protease inhibitors in tumor progression.
Advances in experimental medicine and biology 1997;425():89-97.
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1996: Reisfeld R A; Ferrone S
International Conference on the Biology of Melanoma. Aviano, Italy, 24-26 September 1995.
Melanoma research 1996;6(6):447-56.
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1996: Becker J C; Varki N; Gillies S D; Furukawa K; Reisfeld R A
Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy.
The Journal of clinical investigation 1996;98(12):2801-4.
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1996: Becker J C; Varki N; Bröcker E B; Reisfeld R A
Lymphocyte-mediated alopecia in C57BL/6 mice following successful immunotherapy for melanoma.
The Journal of investigative dermatology 1996;107(4):627-32.
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1996: Becker J C; Varki N; Gillies S D; Furukawa K; Reisfeld R A
An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7826-31.
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1996: Becker J C; Pancook J D; Gillies S D; Furukawa K; Reisfeld R A
T cell-mediated eradication of murine metastatic melanoma induced by targeted interleukin 2 therapy.
The Journal of experimental medicine 1996;183(5):2361-6.
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1996: Reisfeld R A; Gillies S D; Mendelsohn J; Varki N M; Becker J C
Involvement of B lymphocytes in the growth inhibition of human pulmonary melanoma metastases in athymic nu/nu mice by an antibody-lymphotoxin fusion protein.
Cancer research 1996;56(8):1707-12.
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1996: Becker J C; Pancook J D; Gillies S D; Mendelsohn J; Reisfeld R A
Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2702-7.
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1996: Montgomery A M; Becker J C; Siu C H; Lemmon V P; Cheresh D A; Pancook J D; Zhao X; Reisfeld R A
Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3.
The Journal of cell biology 1996;132(3):475-85.
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1996: Pancook J D; Becker J C; Gillies S D; Reisfeld R A
Eradication of established hepatic human neuroblastoma metastases in mice with severe combined immunodeficiency by antibody-targeted interleukin-2.
Cancer immunology, immunotherapy : CII 1996;42(2):88-92.
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1995: Becker J C; Nikroo A; Brabletz T; Reisfeld R A
DNA loops induced by cooperative binding of transcriptional activator proteins and preinitiation complexes.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9727-31.
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1995: Becker J C; Brabletz T; Kirchner T; Conrad C T; Bröcker E B; Reisfeld R A
Negative transcriptional regulation in anergic T cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):2375-8.
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1994: Brooks P C; Montgomery A M; Rosenfeld M; Reisfeld R A; Hu T; Klier G; Cheresh D A
Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels.
Cell 1994;79(7):1157-64.
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1994: Montgomery A M; Mueller B M; Reisfeld R A; Taylor S M; DeClerck Y A
Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line.
Cancer research 1994;54(20):5467-73.
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1994: Sabzevari H; Gillies S D; Mueller B M; Pancook J D; Reisfeld R A
A recombinant antibody-interleukin 2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9626-30.
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1994: Montgomery A M; Reisfeld R A; Cheresh D A
Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):8856-60.
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1994: Reisfeld R A; Mueller B M; Handgretinger R; Yu A L; Gillies S D
Potential of genetically engineered anti-ganglioside GD2 antibodies for cancer immunotherapy.
Progress in brain research 1994;101():201-12.
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1993: Sabzevari H; Reisfeld R A
Human cytotoxic T-cells suppress the growth of spontaneous melanoma metastases in SCID/hu mice.
Cancer research 1993;53(20):4933-7.
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1993: Reisfeld R A
Report of the International Consensus Conference on Human Melanoma Antigens, Lausanne, Switzerland, 12-14 November, 1992.
Melanoma research 1993;3(3):209-17.
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1993: Montgomery A M; Sabzevari H; Reisfeld R A
Production and regulation of gelatinase B by human T-cells.
Biochimica et biophysica acta 1993;1176(3):265-8.
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1993: Montgomery A M; De Clerck Y A; Langley K E; Reisfeld R A; Mueller B M
Melanoma-mediated dissolution of extracellular matrix: contribution of urokinase-dependent and metalloproteinase-dependent proteolytic pathways.
Cancer research 1993;53(3):693-700.
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1993: Barker E; Reisfeld R A
A mechanism for neutrophil-mediated lysis of human neuroblastoma cells.
Cancer research 1993;53(2):362-7.
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1992: Mueller B M; Reisfeld R A; Edgington T S; Ruf W
Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):11832-6.
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1992: Reisfeld R A
Monoclonal antibodies in cancer immunotherapy.
Clinics in laboratory medicine 1992;12(2):201-16.
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1992: Gillies S D; Reilly E B; Lo K M; Reisfeld R A
Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1428-32.
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1991: Gillies S D; Young D; Lo K M; Foley S F; Reisfeld R A
Expression of genetically engineered immunoconjugates of lymphotoxin and a chimeric anti-ganglioside GD2 antibody.
Hybridoma 1991;10(3):347-56.
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1990: Harel W; Shau H; Hadley C G; Morgan A C; Reisfeld R A; Cheresh D A; Mitchell M S
Increased lysis of melanoma by in vivo-elicited human lymphokine-activated killer cells after addition of antiganglioside antibodies in vitro.
Cancer research 1990;50(19):6311-5.
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