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Maarten Reith

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Soumava Santra; Juan Zhen; Tamara Antonio; Sanjib Gogoi; Bhaskar Gopishetty; Maarten E A Reith; Aloke Dutta
Structural exploration of (3S,6S)-6-benzhydryl-N-benzyltetrahydro-2H-pyran-3-amine analogues: identification of potent triple monoamine reuptake inhibitors as potential antidepressants.
Kymry T Jones; Juan Zhen; Maarten E A Reith
Importance of cholesterol in dopamine transporter function.
Maarten E A Reith; Kyle C Schmitt; Henry Sershen; Imran S Sheikh; Naresh Theddu; Ellen M Unterwald; Narendra V Gaddiraju; Audrey Hashim; Suneet Mehrotra; Thomas F Murray; Solav Ali; Franklin A Davis
Novel C-1 substituted cocaine analogs unlike cocaine or benztropine.

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All Publications

2012: Soumava Santra; Juan Zhen; Tamara Antonio; Sanjib Gogoi; Bhaskar Gopishetty; Maarten E A Reith; Aloke Dutta
Structural exploration of (3S,6S)-6-benzhydryl-N-benzyltetrahydro-2H-pyran-3-amine analogues: identification of potent triple monoamine reuptake inhibitors as potential antidepressants.
ChemMedChem 2012;7(12):2093-100.
2012: Kymry T Jones; Juan Zhen; Maarten E A Reith
Importance of cholesterol in dopamine transporter function.
Journal of neurochemistry 2012;123(5):700-15.
2012: Maarten E A Reith; Kyle C Schmitt; Henry Sershen; Imran S Sheikh; Naresh Theddu; Ellen M Unterwald; Narendra V Gaddiraju; Audrey Hashim; Suneet Mehrotra; Thomas F Murray; Solav Ali; Franklin A Davis
Novel C-1 substituted cocaine analogs unlike cocaine or benztropine.
The Journal of pharmacology and experimental therapeutics 2012;343(2):413-25.
2012: Mark Johnson; Maarten E A Reith; Tamara Antonio; Aloke Dutta
Structure-activity relationship study of N⁶-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine analogues: development of highly selective D3 dopamine receptor agonists along with a highly potent D2/D3 agonist and their pharmacological characterization.
Journal of medicinal chemistry 2012;55(12):5826-40.
2012: Kenneth R Alper; Maarten E A Reith; Henry Sershen
Ibogaine and the inhibition of acetylcholinesterase.
Journal of ethnopharmacology 2012;139(3):879-82.
2012: Juan Zhen; Solav Ali; Aloke Dutta; Maarten E A Reith
Characterization of [³H]CFT binding to the norepinephrine transporter suggests that binding of CFT and nisoxetine is not mutually exclusive.
Journal of neuroscience methods 2012;203(1):19-27.
2011: Melissa A Stouffer; Federica Sarti; Solav Ali; Kenneth D Carr; Jyoti C Patel; Maarten E A Reith; Margaret E Rice
SKF-83566, a D1-dopamine receptor antagonist, inhibits the dopamine transporter.
Journal of neurochemistry 2011;118(5):714-20.
2011: Bhaskar Gopishetty; Stuart T Hazeldine; Soumava Santra; Mark Johnson; Gyan Modi; Solav Ali; Juan Zhen; Maarten E A Reith; Aloke Dutta
Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: identification of compounds with triple uptake inhibitory activity as potential antidepressant agents.
Journal of medicinal chemistry 2011;54(8):2924-32.
2011: Kyle C Schmitt; Maarten E A Reith
The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors.
PloS one 2011;6(10):e25790.
2011: Manju A Kurian; Yan Li; Juan Zhen; Esther Meyer; Nebula Hai; Hans-Jürgen Christen; Georg F Hoffmann; Philip Jardine; Arpad von Moers; Santosh R Mordekar; Finbar O'Callaghan; Evangeline Wassmer; Elizabeth Wraige; Christa Dietrich; Timothy Lewis; Keith Hyland; Simon J R Heales; Terence Sanger; Paul Gissen; Birgit E Assmann; Maarten E A Reith; Eamonn R Maher
Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study.
Lancet neurology 2011;10(1):54-62.
2011: Sandhya Kortagere; Shu-Yuan Cheng; Tamara Antonio; Juan Zhen; Maarten E A Reith; Aloke Dutta
Interaction of novel hybrid compounds with the D3 dopamine receptor: Site-directed mutagenesis and homology modeling studies.
Biochemical pharmacology 2011;81(1):157-63.
2010: Angela M Batman; Aloke Dutta; Maarten E A Reith; Patrick M Beardsley
The selective dopamine uptake inhibitor, D-84, suppresses cocaine self-administration, but does not occasion cocaine-like levels of generalization.
European journal of pharmacology 2010;648(1-3):127-32.
2010: Yan Li; Shu-Yuan Cheng; Nianhang Chen; Maarten E A Reith
Interrelation of dopamine transporter oligomerization and surface presence as studied with mutant transporter proteins and amphetamine.
Journal of neurochemistry 2010;114(3):873-85.
2010: Juan Zhen; Tamara Antonio; Aloke Dutta; Maarten E A Reith
Concentration of receptor and ligand revisited in a modified receptor binding protocol for high-affinity radioligands: [3H]Spiperone binding to D2 and D3 dopamine receptors.
Journal of neuroscience methods 2010;188(1):32-8.
2010: Balaram Ghosh; Tamara Antonio; Maarten E A Reith; Aloke Dutta
Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol and its analogues as highly potent dopamine D2/D3 agonists and as iron chelator: in vivo activity indicates potential application in symptomatic and neuroprotective therapy for Parkinson's disease.
Journal of medicinal chemistry 2010;53(5):2114-25.
2010: Kyle C Schmitt; Sreeman Mamidyala; Swati Biswas; Aloke Dutta; Maarten E A Reith
Bivalent phenethylamines as novel dopamine transporter inhibitors: evidence for multiple substrate-binding sites in a single transporter.
Journal of neurochemistry 2010;112(6):1605-18.
2010: Balaram Ghosh; Tamara Antonio; Juan Zhen; Prashant Kharkar; Maarten E A Reith; Aloke Dutta
Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models.
Journal of medicinal chemistry 2010;53(3):1023-37.
2010: Kyle C Schmitt; Maarten E A Reith
Regulation of the dopamine transporter: aspects relevant to psychostimulant drugs of abuse.
Annals of the New York Academy of Sciences 2010;1187():316-40.
2009: Prashant S Kharkar; Angela M Batman; Juan Zhen; Patrick M Beardsley; Maarten E A Reith; Aloke Dutta
Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters.
ChemMedChem 2009;4(7):1075-85.
2009: Manju A Kurian; Juan Zhen; Shu-Yuan Cheng; Yan Li; Santosh Mordekar; Philip Jardine; Neil V Morgan; Esther Meyer; Louise Tee; Shanaz Pasha; Evangeline Wassmer; Simon J R Heales; Paul Gissen; Maarten E A Reith; Eamonn R Maher
Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia.
The Journal of clinical investigation 2009;119(6):1595-603.
2009: Zheng Zhou; Juan Zhen; Nathan K Karpowich; Christopher J Law; Maarten E A Reith; Da-Neng Wang
Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Nature structural & molecular biology 2009;16(6):652-7.
2009: Dennis A Brown; Manoj Mishra; Suhong Zhang; Swati Biswas; Ingrid Parrington; Tamara Antonio; Maarten E A Reith; Aloke Dutta
Investigation of various N-heterocyclic substituted piperazine versions of 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol: effect on affinity and selectivity for dopamine D3 receptor.
Bioorganic & medicinal chemistry 2009;17(11):3923-33.
2009: Ying-Jian Liang; Juan Zhen; Nianhang Chen; Maarten E A Reith
Interaction of catechol and non-catechol substrates with externally or internally facing dopamine transporters.
Journal of neurochemistry 2009;109(4):981-94.
2008: Kyle C Schmitt; Juan Zhen; Prashant Kharkar; Manoj Mishra; Nianhang Chen; Aloke Dutta; Maarten E A Reith
Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.
Journal of neurochemistry 2008;107(4):928-40.
2008: Aloke Dutta; Balaram Ghosh; Swati Biswas; Maarten E A Reith
D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action.
European journal of pharmacology 2008;589(1-3):73-9.
2008: Swati Biswas; Stuart Hazeldine; Balaram Ghosh; Ingrid Parrington; Eldo Kuzhikandathil; Maarten E A Reith; Aloke Dutta
Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: identification of highly potent and selective agonists for dopamine D3 receptor with potent in vivo activity.
Journal of medicinal chemistry 2008;51(10):3005-19.
2008: Nianhang Chen; Maarten E A Reith
Substrates dissociate dopamine transporter oligomers.
Journal of neurochemistry 2008;105(3):910-20.
2008: Manoj Mishra; Rohit Kolhatkar; Juan Zhen; Ingrid Parrington; Maarten E A Reith; Aloke Dutta
Further structural optimization of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine and 1,4-diazabicyclo[3.3.1]nonane derivatives by introducing an exocyclic hydroxyl group: interaction with dopamine, serotonin, and norepinephrine transporters.
Bioorganic & medicinal chemistry 2008;16(6):2769-78.
2008: Swati Biswas; Suhong Zhang; Fernando Fernandez; Balaram Ghosh; Juan Zhen; Eldo Kuzhikandathil; Maarten E A Reith; Aloke Dutta
Further structure-activity relationships study of hybrid 7-{[2-(4-phenylpiperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol analogues: identification of a high-affinity D3-preferring agonist with potent in vivo activity with long duration of action.
Journal of medicinal chemistry 2008;51(1):101-17.
2008: Prashant S Kharkar; Maarten E A Reith; Aloke Dutta
Three-dimensional quantitative structure-activity relationship (3D QSAR) and pharmacophore elucidation of tetrahydropyran derivatives as serotonin and norepinephrine transporter inhibitors.
Journal of computer-aided molecular design 2008;22(1):1-17.
2007: Zheng Zhou; Juan Zhen; Nathan K Karpowich; Regina M Goetz; Christopher J Law; Maarten E A Reith; Da-Neng Wang
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.
Science (New York, N.Y.) 2007;317(5843):1390-3.
2007: Nianhang Chen; Maarten E A Reith
Substrates and inhibitors display different sensitivity to expression level of the dopamine transporter in heterologously expressing cells.
Journal of neurochemistry 2007;101(2):377-88.
2006: Shijun Zhang; Fernando Fernandez; Stuart T Hazeldine; Jeffrey Deschamps; Juan Zhen; Maarten E A Reith; Aloke Dutta
Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters.
Journal of medicinal chemistry 2006;49(14):4239-47.
2006: Shijun Zhang; Juan Zhen; Maarten E A Reith; Aloke Dutta
Design, synthesis, and preliminary SAR study of 3- and 6-side-chain-extended tetrahydro-pyran analogues of cis- and trans-(6-benzhydryl-tetrahydropyran-3-yl)-benzylamine.
Bioorganic & medicinal chemistry 2006;14(11):3953-66.
2006: Juan Zhen; Maarten E A Reith; Kenneth D Carr
Chronic food restriction and dopamine transporter function in rat striatum.
Brain research 2006;1082(1):98-101.
2006: Maarten E A Reith; Juan Zhen; Nianhang Chen
The importance of company: Na+ and Cl- influence substrate interaction with SLC6 transporters and other proteins.
Handbook of experimental pharmacology 2006;(175):75-93.
2005: Aleksej Krunic; S V Santhana Mariappan; Maarten E A Reith; William J Dunn
Synthesis and monoamine transporter affinity of 3-aryl substituted trop-2-enes.
Bioorganic & medicinal chemistry letters 2005;15(24):5488-93.
2005: Juan Zhen; Nianhang Chen; Maarten E A Reith
Differences in interactions with the dopamine transporter as revealed by diminishment of Na(+) gradient and membrane potential: dopamine versus other substrates.
Neuropharmacology 2005;49(6):769-79.
2005: Shijun Zhang; Juan Zhen; Maarten E A Reith; Aloke Dutta
Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner.
Journal of medicinal chemistry 2005;48(15):4962-71.
2005: Maarten E A Reith; Lijuan C Wang; Aloke Dutta
Pharmacological profile of radioligand binding to the norepinephrine transporter: instances of poor indication of functional activity.
Journal of neuroscience methods 2005;143(1):87-94.
2005: Maarten E A Reith
Studying monoamine transporters: beyond hypermonoaminaemia.
Journal of neuroscience methods 2005;143(1):1-2.
2004: Juan Zhen; Soumen Maiti; Nianhang Chen; Aloke Dutta; Maarten E A Reith
Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter.
European journal of pharmacology 2004;506(1):17-26.
2004: Shijun Zhang; Juan Zhen; Maarten E A Reith; Aloke Dutta
Structural requirements for 2,4- and 3,6-disubstituted pyran biomimetics of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine compounds to interact with monoamine transporters.
Bioorganic & medicinal chemistry 2004;12(23):6301-15.
2004: Rohit Kolhatkar; charlie cook; Sujit K Ghorai; Jeffrey Deschamps; Patrick M Beardsley; Maarten E A Reith; Aloke Dutta
Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.
Journal of medicinal chemistry 2004;47(21):5101-13.
2004: Aloke Dutta; Sylesh K Venkataraman; Xiang-Shu Fei; Rohit Kolhatkar; Shijun Zhang; Maarten E A Reith
Synthesis and biological characterization of novel hybrid 7-[[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol and their heterocyclic bioisosteric analogues for dopamine D2 and D3 receptors.
Bioorganic & medicinal chemistry 2004;12(16):4361-73.
2004: Li-Bin Li; Nianhang Chen; Sammanda Ramamoorthy; Limen Chi; Xiao-Nan Cui; Lijuan C Wang; Maarten E A Reith
The role of N-glycosylation in function and surface trafficking of the human dopamine transporter.
The Journal of biological chemistry 2004;279(20):21012-20.
2004: Nianhang Chen; Juan Zhen; Maarten E A Reith
Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.
Journal of neurochemistry 2004;89(4):853-64.
2004: Nianhang Chen; Maarten E A Reith
Interaction between dopamine and its transporter: role of intracellular sodium ions and membrane potential.
Journal of neurochemistry 2004;89(3):750-65.
2004: Nianhang Chen; Judy Rickey; Janet L Berfield; Maarten E A Reith
Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding.
The Journal of biological chemistry 2004;279(7):5508-19.
2004: Nian-Hang Chen; Maarten E A Reith; Michael W Quick
Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6.
Pflügers Archiv : European journal of physiology 2004;447(5):519-31.
2004: Michael Appell; Janet L Berfield; Lijuan C Wang; William J Dunn; Nianhang Chen; Maarten E A Reith
Structure-activity relationships for substrate recognition by the human dopamine transporter.
Biochemical pharmacology 2004;67(2):293-302.
2003: Lijuan C Wang; Xiao-Nan Cui; Nianhang Chen; Maarten E A Reith
Binding of cocaine-like radioligands to the dopamine transporter at 37 degrees C: effect of Na+ and substrates.
Journal of neuroscience methods 2003;131(1-2):27-33.
2003: Limen Chi; Maarten E A Reith
Substrate-induced trafficking of the dopamine transporter in heterologously expressing cells and in rat striatal synaptosomal preparations.
The Journal of pharmacology and experimental therapeutics 2003;307(2):729-36.
2003: Nianhang Chen; Maarten E A Reith
Na+ and the substrate permeation pathway in dopamine transporters.
European journal of pharmacology 2003;479(1-3):213-21.
2003: Aloke Dutta; Shijun Zhang; Rohit Kolhatkar; Maarten E A Reith
Dopamine transporter as target for drug development of cocaine dependence medications.
European journal of pharmacology 2003;479(1-3):93-106.
2003: Nianhang Chen; Michael Appell; Janet L Berfield; Maarten E A Reith
Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter.
European journal of pharmacology 2003;478(2-3):89-95.
2003: Nianhang Chen; Judy Rickey; Maarten E A Reith
Na+ stimulates binding of dopamine to the dopamine transporter in cells but not in cell-free preparations.
Journal of neurochemistry 2003;86(3):678-86.
2003: Rohit Kolhatkar; Sujit K Ghorai; Clifford George; Maarten E A Reith; Aloke Dutta
Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
Journal of medicinal chemistry 2003;46(11):2205-15.
2003: Shijun Zhang; Maarten E A Reith; Aloke Dutta
Design, synthesis, and activity of novel cis- and trans-3,6-disubstituted pyran biomimetics of 3,6-disubstituted piperidine as potential ligands for the dopamine transporter.
Bioorganic & medicinal chemistry letters 2003;13(9):1591-5.
2003: Sujit K Ghorai; Charles Cook; Matthew Davis; Sylesh K Venkataraman; Clifford George; Patrick M Beardsley; Maarten E A Reith; Aloke Dutta
High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.
Journal of medicinal chemistry 2003;46(7):1220-8.
2002: Bo-Jin Cao; Maarten E A Reith
Nitric oxide inhibits uptake of dopamine and N-methyl-4-phenylpyridinium (MPP+) but not release of MPP+ in rat C6 glioma cells expressing human dopamine transporter.
British journal of pharmacology 2002;137(8):1155-62.
2002: Qun Wu; Maarten E A Reith; Q David Walker; Cynthia M Kuhn; Frank carroll; Paul Garris
Concurrent autoreceptor-mediated control of dopamine release and uptake during neurotransmission: an in vivo voltammetric study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(14):6272-81.
2002: Bo-Jin Cao; Maarten E A Reith
Nitric oxide scavenger carboxy-PTIO potentiates the inhibition of dopamine uptake by nitric oxide donors.
European journal of pharmacology 2002;448(1):27-30.
2002: Nianhang Chen; LingLing Sun; Maarten E A Reith
Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl)tropane.
Journal of neurochemistry 2002;81(6):1383-93.
2002: Michael Appell; William J Dunn; Maarten E A Reith; Larry Miller; Judith L Flippen-Anderson
An analysis of the binding of cocaine analogues to the monoamine transporters using tensor decomposition 3-d QSAR.
Bioorganic & medicinal chemistry 2002;10(5):1197-206.
2002: Li-Bin Li; Xiao-Nan Cui; Maarten E A Reith
Is Na(+) required for the binding of dopamine, amphetamine, tyramine, and octopamine to the human dopamine transporter?
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(4):303-11.
2002: Aloke Dutta; Xiang-Shu Fei; Maarten E A Reith
A novel series of hybrid compounds derived by combining 2-aminotetralin and piperazine fragments: binding activity at D2 and D3 receptors.
Bioorganic & medicinal chemistry letters 2002;12(4):619-22.
2002: Aloke Dutta; Matthew C Davis; Xiang-Shu Fei; Patrick M Beardsley; charlie cook; Maarten E A Reith
Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules.
Journal of medicinal chemistry 2002;45(3):654-62.
2001: Qun Wu; Maarten E A Reith; R Mark Wightman; K T Kawagoe; Paul Garris
Determination of release and uptake parameters from electrically evoked dopamine dynamics measured by real-time voltammetry.
Journal of neuroscience methods 2001;112(2):119-33.
2001: Aloke Dutta; M C Davis; Maarten E A Reith
Rational design and synthesis of novel 2,5-disubstituted cis- and trans-piperidine derivatives exhibiting differential activity for the dopamine transporter.
Bioorganic & medicinal chemistry letters 2001;11(17):2337-40.
2001: Qun Wu; Maarten E A Reith; Michael J Kuhar; Frank carroll; Paul Garris
Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(16):6338-47.
2001: Maarten E A Reith; Janet L Berfield; Lijuan C Wang; Jasmine V Ferrer; Jonathan A Javitch
The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter.
The Journal of biological chemistry 2001;276(31):29012-8.
2001: Nianhang Chen; Roxanne A Vaughan; Maarten E A Reith
The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis.
Journal of neurochemistry 2001;77(4):1116-27.
2001: Roxanne A Vaughan; Jon D Gaffaney; John R Lever; Maarten E A Reith; Aloke Dutta
Dual incorporation of photoaffinity ligands on dopamine transporters implicates proximity of labeled domains.
Molecular pharmacology 2001;59(5):1157-64.
2001: Aloke Dutta; Xiang-Shu Fei; Patrick M Beardsley; Jennifer Newman; Maarten E A Reith
Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.
Journal of medicinal chemistry 2001;44(6):937-48.
2001: Aloke Dutta; Xiang-Shu Fei; Roxanne A Vaughan; Jon D Gaffaney; N Wang; John R Lever; Maarten E A Reith
Design, synthesis, and characterization of a novel, 4-[2-(diphenylmethoxy)ethyl]-1-benzyl piperidine-based, dopamine transporter photoaffinity label.
Life sciences 2001;68(16):1839-49.
2001: Aloke Dutta; Maarten E A Reith; B K Madras
Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter.
Synapse (New York, N.Y.) 2001;39(2):175-81.
2000: Nianhang Chen; Maarten E A Reith
Structure and function of the dopamine transporter.
European journal of pharmacology 2000;405(1-3):329-39.
2000: Lijuan C Wang; Janet L Berfield; Michael J Kuhar; F I Carroll; Maarten E A Reith
RTI-76, an isothiocyanate derivative of a phenyltropane cocaine analog, as a tool for irreversibly inactivating dopamine transporter function in vitro.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(3):238-47.
2000: Dong Ook Seo; Chang Yell Shin; Jae Ryun Ryu; Jae Hoon Cheong; Chang-Rak Choi; John W Dailey; Maarten E A Reith; Phillip C Jobe; Kwang Ho Ko
Effect of norepinephrine release on adrenoceptors in severe seizure genetically epilepsy-prone rats.
European journal of pharmacology 2000;396(2-3):53-8.
2000: Q Yan; Maarten E A Reith; S Yan
Enhanced accumbal dopamine release following 5-HT(2A) receptor stimulation in rats pretreated with intermittent cocaine.
Brain research 2000;863(1-2):254-8.
2000: Li-Bin Li; Maarten E A Reith
Interaction of Na+, K+, and Cl- with the binding of amphetamine, octopamine, and tyramine to the human dopamine transporter.
Journal of neurochemistry 2000;74(4):1538-52.
1999: Li-Bin Li; Maarten E A Reith
Modeling of the interaction of Na+ and K+ with the binding of dopamine and [3H]WIN 35,428 to the human dopamine transporter.
Journal of neurochemistry 1999;72(3):1095-109.
1999: Janet L Berfield; Lijuan C Wang; Maarten E A Reith
Which form of dopamine is the substrate for the human dopamine transporter: the cationic or the uncharged species?
The Journal of biological chemistry 1999;274(8):4876-82.
1999: Dong Ook Seo; Chang Yell Shin; C J Lee; John W Dailey; Maarten E A Reith; Phillip C Jobe; Kwang Ho Ko
Effect of alterations in extracellular norepinephrine on adrenoceptors: a microdialysis study in freely moving rats.
European journal of pharmacology 1999;365(1):39-46.
1998: Qing-Shan Yan; Maarten E A Reith; S G Yan; Phillip C Jobe
Effect of systemic ethanol on basal and stimulated glutamate releases in the nucleus accumbens of freely moving Sprague-Dawley rats: a microdialysis study.
Neuroscience letters 1998;258(1):29-32.
1998: John W Dailey; Maarten E A Reith; K R Steidley; Joseph C. Milbrandt; Phillip C Jobe
Carbamazepine-induced release of serotonin from rat hippocampus in vitro.
Epilepsia 1998;39(10):1054-63.
1998: Aloke Dutta; C Xu; Maarten E A Reith
Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
Journal of medicinal chemistry 1998;41(17):3293-7.
1998: Aloke Dutta; LL Coffey; Maarten E A Reith
Potent and selective ligands for the dopamine transporter (DAT): structure-activity relationship studies of novel 4-[2-(diphenylmethoxy)ethyl]-1-(3-phenylpropyl)piperidine analogues.
Journal of medicinal chemistry 1998;41(5):699-705.
1998: N H Chen; Maarten E A Reith
In vivo microdialysis for measurement of extracellular monoamine levels following inhibition of monoamine transporters.
Methods in enzymology 1998;296():719-30.
1998: Maarten E A Reith; C Xu; F I Carroll; N H Chen
Inhibition of [3H]dopamine translocation and [3H]cocaine analog binding: a potential screening device for cocaine antagonists.
Methods in enzymology 1998;296():248-59.
1997: MY Li; Maarten E A Reith
Effect of quinine on autoreceptor-regulated serotonin release in the rat hippocampus.
European journal of pharmacology 1997;340(2-3):145-51.
1997: Maarten E A Reith; MY Li; Qing-Shan Yan
Extracellular dopamine, norepinephrine, and serotonin in the ventral tegmental area and nucleus accumbens of freely moving rats during intracerebral dialysis following systemic administration of cocaine and other uptake blockers.
Psychopharmacology 1997;134(3):309-17.
1997: Qun Wu; LL Coffey; Maarten E A Reith
Cations affect [3H]mazindol and [3H]WIN 35,428 binding to the human dopamine transporter in a similar fashion.
Journal of neurochemistry 1997;69(3):1106-18.
1997: NH Chen; Jian-Hua Ding; YL Wang; Maarten E A Reith
Potential misconceptions in dopamine transporter assays arising from the binding of [125I]RTI-121 to filters: effect of ions and cocaine.
Journal of neuroscience methods 1997;75(2):179-86.
1997: Qing-Shan Yan; Maarten E A Reith; Phillip C Jobe; John W Dailey
Dizocilpine (MK-801) increases not only dopamine but also serotonin and norepinephrine transmissions in the nucleus accumbens as measured by microdialysis in freely moving rats.
Brain research 1997;765(1):149-58.
1997: C Xu; Maarten E A Reith
WIN 35,428 and mazindol are mutually exclusive in binding to the cloned human dopamine transporter.
The Journal of pharmacology and experimental therapeutics 1997;282(2):920-7.
1997: John W Dailey; Maarten E A Reith; Qing-Shan Yan; MY Li; Phillip C Jobe
Carbamazepine increases extracellular serotonin concentration: lack of antagonism by tetrodotoxin or zero Ca2+.
European journal of pharmacology 1997;328(2-3):153-62.
1997: John W Dailey; Maarten E A Reith; Qing-Shan Yan; MY Li; Phillip C Jobe
Anticonvulsant doses of carbamazepine increase hippocampal extracellular serotonin in genetically epilepsy-prone rats: dose response relationships.
Neuroscience letters 1997;227(1):13-6.
1997: NH Chen; Jian-Hua Ding; YL Wang; Maarten E A Reith
Modeling of the interaction of Na+ and K+ with the binding of the cocaine analogue 3beta-(4-[125I]iodophenyl)tropane-2beta-carboxylic acid isopropyl ester to the dopamine transporter.
Journal of neurochemistry 1997;68(5):1968-81.
1997: Maarten E A Reith; C Xu; N H Chen
Pharmacology and regulation of the neuronal dopamine transporter.
European journal of pharmacology 1997;324(1):1-10.
1997: L Zhang; LL Coffey; Maarten E A Reith
Regulation of the functional activity of the human dopamine transporter by protein kinase C.
Biochemical pharmacology 1997;53(5):677-88.
1997: NH Chen; YL Wang; Maarten E A Reith
Binding of the [125I]3 beta-(iodophenyl)tropan-2 beta-carboxylic acid isopropyl ester to the dopamine transporter at a physiologically relevant temperature: mutually exclusive binding and different ionic requirements for various uptake blockers and substrates.
Synapse (New York, N.Y.) 1997;25(2):155-62.
1997: Aloke Dutta; LL Coffey; Maarten E A Reith
Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity.
Journal of medicinal chemistry 1997;40(1):35-43.
1997: C Xu; LL Coffey; Maarten E A Reith
Binding domains for blockers and substrates on the dopamine transporter in rat striatal membranes studied by protection against N-ethylmaleimide-induced reduction of [3H]WIN 35,428 binding.
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(1):64-73.
1996: L Zhang; Maarten E A Reith
Regulation of the functional activity of the human dopamine transporter by the arachidonic acid pathway.
European journal of pharmacology 1996;315(3):345-54.
1996: Maarten E A Reith; C Xu; L L Coffey
Binding domains for blockers and substrates on the cloned human dopamine transporter studied by protection against N-ethylmaleimide-induced reduction of 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)[3H]tropane ([3H]WIN 35,428) binding.
Biochemical pharmacology 1996;52(9):1435-46.
1996: C Xu; Maarten E A Reith
Modeling of the pH dependence of the binding of WIN 35,428 to the dopamine transporter in rat striatal membranes: is the bioactive form positively charged or neutral?
The Journal of pharmacology and experimental therapeutics 1996;278(3):1340-8.
1996: S Y Chen; R I Burger; Maarten E A Reith
Extracellular dopamine in the rat ventral tegmental area and nucleus accumbens following ventral tegmental infusion of cocaine.
Brain research 1996;729(2):294-6.
1996: Maarten E A Reith; C Xu; L Zhang; L L Coffey
Translocation of dopamine and binding of WIN 35,428 measured under identical conditions in cells expressing the cloned human dopamine transporter.
Naunyn-Schmiedeberg's archives of pharmacology 1996;354(3):295-304.
1996: Qing-Shan Yan; Maarten E A Reith; Phillip C Jobe; John W Dailey
Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area.
European journal of pharmacology 1996;301(1-3):49-57.
1996: NH Chen; C Xu; L L Coffey; Maarten E A Reith
[3H]WIN 35,428 [2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] binding to rat brain membranes. Comparing dopamine cell body areas with nerve terminal regions.
Biochemical pharmacology 1996;51(4):563-6.
1996: Aloke Dutta; C Xu; Maarten E A Reith
Structure-activity relationship studies of novel 4-[2-[bis(4-fluorophenyl)methoxy]ethyl]-1-(3-phenylpropyl)piperidine analogs: synthesis and biological evaluation at the dopamine and serotonin transporter sites.
Journal of medicinal chemistry 1996;39(3):749-56.
1996: L L Coffey; Maarten E A Reith; NH Chen; P K Mishra; Phillip C Jobe
Amygdala kindling of forebrain seizures and the occurrence of brainstem seizures in genetically epilepsy-prone rats.
Epilepsia 1996;37(2):188-97.
1996: MY Li; Qing-Shan Yan; L L Coffey; Maarten E A Reith
Extracellular dopamine, norepinephrine, and serotonin in the nucleus accumbens of freely moving rats during intracerebral dialysis with cocaine and other monoamine uptake blockers.
Journal of neurochemistry 1996;66(2):559-68.
1996: Kathryn A Cunningham; C W Bradberry; A S Chang; Maarten E A Reith
The role of serotonin in the actions of psychostimulants: molecular and pharmacological analyses.
Behavioural brain research 1996;73(1-2):93-102.
1995: NH Chen; Maarten E A Reith
Monoamine interactions measured by microdialysis in the ventral tegmental area of rats treated systemically with (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin.
Journal of neurochemistry 1995;64(4):1585-97.
1995: C Xu; L L Coffey; Maarten E A Reith
Translocation of dopamine and binding of 2 beta-carbomethoxy-3 beta-(4-fluorophenyl) tropane (WIN 35,428) measured under identical conditions in rat striatal synaptosomal preparations. Inhibition by various blockers.
Biochemical pharmacology 1995;49(3):339-50.
1995: Joseph Thomas Hjelle; A K Ho; MA Miller-Hjelle; Maarten E A Reith; K R Steidley; R Duffield; T Butler; J W Dobbie
Multiple drug classes and hyperosmolarity alter binding of muscarinic drugs to mesothelial cells in vitro.
Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 1995;11():3-6.
1994: NH Chen; Maarten E A Reith
Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine: a microdialysis study in freely moving rats.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1597-610.
1994: Maarten E A Reith; L L Coffey
Structure-activity relationships for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1444-52.
1994: NH Chen; Maarten E A Reith
Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: a microdialysis study on monoamine interrelationships.
Journal of neurochemistry 1994;63(5):1701-13.
1994: NH Chen; C Wang; Phillip C Jobe; Maarten E A Reith
Facilitation of amygdala kindling development and kindled seizures by metaphit.
Epilepsia 1994;35(5):927-32.
1994: Bertha K Madras; Maarten E A Reith; Peter C Meltzer; Aloke Dutta
O-526, a piperidine analog of GBR 12909, retains high affinity for the dopamine transporter in monkey caudate-putamen.
European journal of pharmacology 1994;267(2):167-73.
1994: Maarten E A Reith; L L Coffey; C Xu; NH Chen
GBR 12909 and 12935 block dopamine uptake into brain synaptic vesicles as well as nerve endings.
European journal of pharmacology 1994;253(1-2):175-8.
1994: Maarten E A Reith; L L Coffey
[3H]WIN 35,428 binding to the dopamine uptake carrier. II. Effect of membrane fractionation procedure and freezing.
Journal of neuroscience methods 1994;51(1):31-8.
1994: L L Coffey; Maarten E A Reith
[3H]WIN 35,428 binding to the dopamine uptake carrier. I. Effect of tonicity and buffer composition.
Journal of neuroscience methods 1994;51(1):23-30.
1993: NH Chen; Maarten E A Reith
Dopamine and serotonin release-regulating autoreceptor sensitivity in A9/A10 cell body and terminal areas after withdrawal of rats from continuous infusion of cocaine.
The Journal of pharmacology and experimental therapeutics 1993;267(3):1445-53.
1993: NH Chen; Maarten E A Reith
[3H]dopamine and [3H]serotonin release in vitro induced by electrical stimulation in A9 and A10 dopamine regions of rat brain: characterization and responsiveness to cocaine.
The Journal of pharmacology and experimental therapeutics 1993;267(1):379-89.
1993: H L Wiener; Maarten E A Reith
Unknown radioligand specific activity.
Trends in pharmacological sciences 1993;14(8):294-6.
1993: Maarten E A Reith; L L Coffey
Cationic and anionic requirements for the binding of 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)[3H]tropane to the dopamine uptake carrier.
Journal of neurochemistry 1993;61(1):167-77.
1993: Milo Lipovac; E A Debler; Berislav V Zlokovic; A E Jacobson; K C Rice; B de Costa; G Selmeci; L Chi; Maarten E A Reith
Metaphit-induced audiogenic seizures in mice: II. Studies on N-methyl-D-aspartic acid, GABA, and sodium channel receptors and on the disposition of metaphit in the brain.
Epilepsia 1993;34(2):211-9.
1993: E A Debler; Milo Lipovac; Abel Lajtha; Berislav V Zlokovic; D S Dunlop; A E Jacobson; K C Rice; B de Costa; Maarten E A Reith
Metaphit-induced audiogenic seizures in mice: I. Pharmacologic characterization.
Epilepsia 1993;34(2):201-10.
1992: Maarten E A Reith; B de Costa; K C Rice; A E Jacobson
Evidence for mutually exclusive binding of cocaine, BTCP, GBR 12935, and dopamine to the dopamine transporter.
European journal of pharmacology 1992;227(4):417-25.
1992: H L Wiener; Maarten E A Reith
Determination of radioligand specific activity using competition binding assays.
Analytical biochemistry 1992;207(1):58-62.
1992: M Benuck; Maarten E A Reith
Dopamine releasing effect of phenylbiguanide in rat striatal slices.
Naunyn-Schmiedeberg's archives of pharmacology 1992;345(6):666-72.
1992: Maarten E A Reith; G Selmeci
Radiolabeling of dopamine uptake sites in mouse striatum: comparison of binding sites for cocaine, mazindol, and GBR 12935.
Naunyn-Schmiedeberg's archives of pharmacology 1992;345(3):309-18.
1992: Maarten E A Reith; G Selmeci
Cocaine binding sites in mouse striatum, dopamine autoreceptors, and cocaine-induced locomotion.
Pharmacology, biochemistry, and behavior 1992;41(1):227-30.
1991: Maarten E A Reith; A E Jacobson; K C Rice; M Benuck; I Zimanyi
Effect of metaphit on dopaminergic neurotransmission in rat striatal slices: involvement of the dopamine transporter and voltage-dependent sodium channel.
The Journal of pharmacology and experimental therapeutics 1991;259(3):1188-96.
1991: Veselinka Susic; Maarten E A Reith; Berislav V Zlokovic; Abel Lajtha; A E Jacobson; K C Rice; Milo Lipovac
Electroencephalographic characteristics of audiogenic seizures induced in metaphit-treated small rodents.
Epilepsia 1991;32(6):783-90.
1991: E A Debler; Henry Sershen; Audrey Hashim; Abel Lajtha; Maarten E A Reith
Carrier-mediated efflux of [3H]dopamine and [3H]1-methyl-4-phenylpyridine: effect of ascorbic acid.
Synapse (New York, N.Y.) 1991;7(2):99-105.
1991: Maarten E A Reith; C T Fischette
Sertraline and cocaine-induced locomotion in mice. II. Chronic studies.
Psychopharmacology 1991;103(3):306-13.
1991: Maarten E A Reith; H L Wiener; C T Fischette
Sertraline and cocaine-induced locomotion in mice. I. Acute studies.
Psychopharmacology 1991;103(3):297-305.
1990: H L Wiener; Maarten E A Reith
Differential effects of daily administration of cocaine on hepatic and cerebral glutathione in mice.
Biochemical pharmacology 1990;40(8):1763-8.
1990: Maarten E A Reith
5-HT3 receptor antagonists attenuate cocaine-induced locomotion in mice.
European journal of pharmacology 1990;186(2-3):327-30.
1990: H L Wiener; Maarten E A Reith
Correlation between cocaine-induced locomotion and cocaine disposition in the brain among four inbred strains of mice.
Pharmacology, biochemistry, and behavior 1990;36(3):699-701.
1990: Maarten E A Reith; C A O'Reilly
Inhibition of serotonin uptake into mouse brain synaptosomes by ionophores and ion-channel agents.
Brain research 1990;521(1-2):347-51.
1990: H L Wiener; H K Kramer; Maarten E A Reith
Separation and determination of sertraline and its metabolite, desmethylsertraline, in mouse cerebral cortex by reversed-phase high-performance liquid chromatography.
Journal of chromatography 1990;527(2):467-72.
1990: P Berger; John D Elsworth; Maarten E A Reith; D Tanen; Robert H Roth
Complex interaction of cocaine with the dopamine uptake carrier.
European journal of pharmacology 1990;176(2):251-2.
1990: Maarten E A Reith; H K Kramer; Henry Sershen; Abel Lajtha
D-tartrate alters uptake of [3H]dopamine into brain synaptic vesicles.
Journal of neuroscience methods 1990;31(2):133-6.
1990: Maarten E A Reith
[14C]guanidinium ion influx into Na+ channel preparations from mouse cerebral cortex.
European journal of pharmacology 1990;188(1):33-41.
1989: H K Kramer; Henry Sershen; Abel Lajtha; Maarten E A Reith
The effect of nicotine on catecholaminergic storage vesicles.
Brain research 1989;503(2):296-8.
1989: I Zimányi; Abel Lajtha; Maarten E A Reith
Comparison of characteristics of dopamine uptake and mazindol binding in mouse striatum.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(6):626-32.
1989: I Zimányi; S R Weiss; Abel Lajtha; R M Post; Maarten E A Reith
Evidence for a common site of action of lidocaine and carbamazepine in voltage-dependent sodium channels.
European journal of pharmacology 1989;167(3):419-22.
1989: M Benuck; Maarten E A Reith; Abel Lajtha
Phosphoinositide hydrolysis induced by depolarization and sodium channel activation in mouse cerebrocortical slices.
Neuropharmacology 1989;28(8):847-54.
1989: Maarten E A Reith; I Zimanyi; C A O'Reilly
Role of ions and membrane potential in uptake of serotonin into plasma membrane vesicles from mouse brain.
Biochemical pharmacology 1989;38(13):2091-7.
1989: E A Debler; Milo Lipovac; Abel Lajtha; Berislav V Zlokovic; A E Jacobson; K C Rice; Maarten E A Reith
Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice.
European journal of pharmacology 1989;165(1):155-9.
1989: I Zimányi; E Wang; Abel Lajtha; Maarten E A Reith
Effect of cocaine and cocaine congeners on veratridine-induced depolarization in mouse cerebrocortical synaptoneurosomes.
Journal of neuroscience research 1989;22(2):201-8.
1989: M Benuck; Maarten E A Reith; Abel Lajtha
Evidence for the involvement of Na+/Ca2+ exchange in the stimulation of inositol phospholipid hydrolysis by sodium channel activation and depolarization.
European journal of pharmacology 1989;159(2):187-90.
1989: M Benuck; Maarten E A Reith; Henry Sershen; H L Wiener; Abel Lajtha
Oxidative metabolism of cocaine: comparison of brain and liver.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1989;190(1):7-13.
1989: I Zimányi; A E Jacobson; K C Rice; Abel Lajtha; Maarten E A Reith
Long-term blockade of the dopamine uptake complex by metaphit, an isothiocyanate derivative of phencyclidine.
Synapse (New York, N.Y.) 1989;3(3):239-45.
1988: I Zimanyi; Abel Lajtha; E S Vizi; E Wang; Maarten E A Reith
Evidence that there is no direct correlation between alpha 2-adrenoceptor antagonism and inhibition of voltage-dependent sodium channels.
Neuropharmacology 1988;27(11):1205-8.
1988: C A O'Reilly; Maarten E A Reith
Uptake of [3H]serotonin into plasma membrane vesicles from mouse cerebral cortex.
The Journal of biological chemistry 1988;263(13):6115-21.
1988: M Benuck; Maarten E A Reith; Abel Lajtha
Presence of the toxic metabolite N-hydroxy-norcocaine in brain and liver of the mouse.
Biochemical pharmacology 1988;37(6):1169-72.
1988: S S Kim; Maarten E A Reith
Inhibition by cocaine of inositol phospholipid hydrolysis induced by the sodium channel activator batrachotoxin in mouse cerebral cortex.
Biochemical pharmacology 1988;37(4):773-5.
1988: I Zimanyi; Abel Lajtha; E S Vizi; Maarten E A Reith
Interaction of yohimbine with batrachotoxinin binding to mouse brain sodium channels.
Biochemical pharmacology 1988;37(4):641-5.
1988: I Zimányi; Abel Lajtha; Maarten E A Reith
The mode of action of ethanol on batrachotoxinin-A benzoate binding to sodium channels in mouse brain cortex.
European journal of pharmacology 1988;146(1):7-16.
1988: Henry Sershen; P Berger; A E Jacobson; K C Rice; Maarten E A Reith
Metaphit prevents locomotor activation induced by various psychostimulants and interferes with the dopaminergic system in mice.
Neuropharmacology 1988;27(1):23-30.
1988: Maarten E A Reith
Cocaine receptors on monoamine transporters and sodium channels.
NIDA research monograph 1988;88():23-43.
1988: E R Korpi; Maarten E A Reith; A Lajtha
Synaptosomal sodium channels in rat lines selected for alcohol-related behaviors.
Alcohol (Fayetteville, N.Y.) 1988;5(1):81-4.
1987: Maarten E A Reith; S S Kim; Abel Lajtha
Binding sites for [3H]tetracaine in synaptosomal sodium channel preparations from mouse brain.
European journal of pharmacology 1987;143(2):171-8.
1987: Maarten E A Reith; M Benuck; Abel Lajtha
Cocaine disposition in the brain after continuous or intermittent treatment and locomotor stimulation in mice.
The Journal of pharmacology and experimental therapeutics 1987;243(1):281-7.
1987: M Benuck; Abel Lajtha; Maarten E A Reith
Pharmacokinetics of systemically administered cocaine and locomotor stimulation in mice.
The Journal of pharmacology and experimental therapeutics 1987;243(1):144-9.
1987: Henry Sershen; M Banay-Schwartz; D S Dunlop; E A Debler; Maarten E A Reith
Nicotine-induced changes in the metabolism of specific brain proteins.
Neurochemical research 1987;12(2):197-202.
1987: Maarten E A Reith; Henry Sershen; Abel Lajtha
Effects of caffeine on monoaminergic systems in mouse brain.
Acta biochimica et biophysica Hungarica 1987;22(2-3):149-63.
1986: Henry Sershen; M F Mason; Maarten E A Reith; A Hashim; Abel Lajtha
Effect of nicotine and amphetamine on the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice.
Neuropharmacology 1986;25(11):1231-4.
1986: Maarten E A Reith
Effect of repeated administration of various doses of cocaine and WIN 35,065-2 on locomotor behavior of mice.
European journal of pharmacology 1986;130(1-2):65-72.
1986: Henry Sershen; M F Mason; Maarten E A Reith; A Hashim; Abel Lajtha
Effect of amphetamine on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice.
Neuropharmacology 1986;25(8):927-30.
1986: S S Kim; Maarten E A Reith
Effect of serotonin on the dissociation of high-affinity binding of [3H]imipramine in mouse cerebral cortex.
Neuroscience letters 1986;67(2):123-8.
1986: Maarten E A Reith; S S Kim; A Lajtha
Structural requirements for cocaine congeners to interact with [3H]batrachotoxinin A 20-alpha-benzoate binding sites on sodium channels in mouse brain synaptosomes.
The Journal of biological chemistry 1986;261(16):7300-5.
1986: Maarten E A Reith; B E Meisler; H Sershen; A Lajtha
Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior.
Biochemical pharmacology 1986;35(7):1123-9.
1986: Maarten E A Reith
Binding of [3H]imipramine to mouse cerebrocortical membranes and to glass fiber filters.
Journal of neurochemistry 1986;46(3):760-6.
1986: Maarten E A Reith; A Lajtha
Locomotor depression in mice by norcocaine does not involve central alpha 2-adrenergic or presynaptic dopamine receptors.
Pharmacology, biochemistry, and behavior 1986;24(2):305-7.
1986: Maarten E A Reith; H Sershen; A Lajtha
Binding sites for [3H]cocaine in mouse striatum and cerebral cortex have different dissociation kinetics.
Journal of neurochemistry 1986;46(1):309-12.
1985: H Sershen; Maarten E A Reith; A Hashim; A Lajtha
Protection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity by the antioxidant ascorbic acid.
Neuropharmacology 1985;24(12):1257-9.
1985: Maarten E A Reith; B E Meisler; A Lajtha
Locomotor effects of cocaine, cocaine congeners, and local anesthetics in mice.
Pharmacology, biochemistry, and behavior 1985;23(5):831-6.
1985: Maarten E A Reith; B E Meisler; H Sershen; A Lajtha
Sodium-independent binding of [3H]cocaine in mouse striatum is serotonin related.
Brain research 1985;342(1):145-8.
1985: Maarten E A Reith
Possible artefacts in imipramine binding assays.
Journal of neurochemistry 1985;45(2):661-3.
1985: H Sershen; Maarten E A Reith; A Hashim; A Lajtha
Comparison of [3H]nicotine and [3H]acetylcholine binding in mouse brain: regional distribution.
Research communications in chemical pathology and pharmacology 1985;48(3):345-52.
1984: Maarten E A Reith; H Sershen; A Lajtha
Thermodynamics of the interactions of tricyclic drugs with binding sites for [3H]imipramine in mouse cerebral cortex.
Biochemical pharmacology 1984;33(24):4101-4.
1984: Maarten E A Reith; B E Meisler; H Sershen; A Lajtha
[3H]cocaine binding in brain is inhibited by Tris (hydroxymethyl) aminomethane.
Journal of neuroscience methods 1984;12(2):151-4.
1984: Maarten E A Reith; D L Allen; H Sershen; A Lajtha
Similarities and differences between high-affinity binding sites for cocaine and imipramine in mouse cerebral cortex.
Journal of neurochemistry 1984;43(1):249-55.
1984: Maarten E A Reith; H Sershen; A Lajtha
Binding of imipramine and cocaine to a model lipid membrane: comparison with binding to brain membranes.
Neurochemical research 1984;9(7):965-77.
1984: H Sershen; Maarten E A Reith; A Hashim; A Lajtha
Reduction of dopamine uptake and cocaine binding in mouse striatum by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
European journal of pharmacology 1984;102(1):175-8.
1984: H Sershen; Maarten E A Reith; A Hashim; A Lajtha
Endogenous material in brain inhibiting [3H]nicotine and [3H]acetylcholine binding.
Journal of neuroscience research 1984;12(4):563-9.
1983: D L Allen; Maarten E A Reith; H Sershen; A Lajtha
Imipramine does not act as a false transmitter in the rat hypothalamus.
Brain research 1983;267(1):161-4.
1983: Maarten E A Reith; H Sershen; D L Allen; A Lajtha
A portion of [3H]cocaine binding in brain is associated with serotonergic neurons.
Molecular pharmacology 1983;23(3):600-6.
1983: Maarten E A Reith; H Sershen; D Allen; A Lajtha
High- and low-affinity binding of [3H]imipramine in mouse cerebral cortex.
Journal of neurochemistry 1983;40(2):389-95.
1982: H Sershen; Maarten E A Reith; M Banay-Schwartz; A Lajtha
Effects of prenatal administration of nicotine on amino acid pools, protein metabolism, and nicotine binding in the brain.
Neurochemical research 1982;7(12):1515-22.
1982: H Sershen; Maarten E A Reith; A Lajtha
On the interaction between nicotine and cycloheximide.
Brain research 1982;251(1):183-5.
1982: H Sershen; Maarten E A Reith; A Lajtha
Comparison of the properties of central and peripheral binding sites for cocaine.
Neuropharmacology 1982;21(5):469-74.
1981: Maarten E A Reith; H Sershen; C Vadasz; A Lajtha
Strain differences in opiate receptors in mouse brain.
European journal of pharmacology 1981;74(4):377-80.
1981: Henry Sershen; Maarten E A Reith; Abel Lajtha; J Gennaro
Effect of cigarette smoke on protein synthesis in brain and liver.
Neuropharmacology 1981;20(5):451-6.
1981: Maarten E A Reith; H Sershen; A Lajtha
Binding of [3H]cocaine in mouse brain: kinetics and saturability.
Journal of receptor research 1981;2(3):233-43.
1981: Henry Sershen; Maarten E A Reith; Abel Lajtha; J Gennaro
Noncholinergic, saturable binding of (+/-)-[3H]nicotine to mouse brain.
Journal of receptor research 1981;2(1):1-15.
1981: Maarten E A Reith; A Neidle
Breakdown and fate of ACTH and MSH.
Pharmacology & therapeutics 1981;12(3):449-61.
1980: Maarten E A Reith; H Sershen; A Lajtha
Endogenous peptide(s) inhibiting [3H]cocaine binding in mouse brain.
Neurochemical research 1980;5(12):1291-9.
1980: H Sershen; Maarten E A Reith; A Lajtha
The pharmacological relevance of the cocaine binding site in mouse brain.
Neuropharmacology 1980;19(11):1145-8.
1980: Maarten E A Reith; H Sershen; A Lajtha
Saturable (3H)cocaine binding in central nervous system of mouse.
Life sciences 1980;27(12):1055-62.
1980: A Neidle; Maarten E A Reith
The degradation of adrenocorticotrophic hormone-(1-4) by mouse brain cytosol.
Archives of biochemistry and biophysics 1980;203(1):288-95.
1979: Maarten E A Reith; A Neidle
The isolation of the two dipeptide hydrolases from mouse brain cytosol.
Biochemical and biophysical research communications 1979;90(3):794-800.
1979: Maarten E A Reith; A Neidle; A Lajtha
Breakdown of corticotropin-(1-24) by mouse brain extracts.
Archives of biochemistry and biophysics 1979;195(2):478-84.
1979: Maarten E A Reith; P Schotman; B J van Zwieten; W H Gispen
The nature of the amino acid pool used for protein synthesis in rat brain slices.
Journal of neurochemistry 1979;32(2):413-20.
1978: Maarten E A Reith; P Schotman; W H Gispen
Measurements of in vivo rates of protein synthesis in brain, spinal cord, heart and liver of young versus adult rats, intact versus hypophysectomized rats.
Journal of neurochemistry 1978;30(3):587-94.
1977: P Schotman; Maarten E A Reith; W H Gispen
Effects of stressful procedures as ether anesthesia and intracranial injections on amino acid incorporation into brain protein.
Brain research bulletin 1977;2(2):83-7.
1977: W H Gispen; Maarten E A Reith; P Schotman; V M Wiegant; H Zwiers; D de Wied
CNS and ACTH-like peptides: neurochemical response and interaction with opiates.
Advances in biochemical psychopharmacology 1977;17():61-80.
1975: Maarten E A Reith; P Schotman; W H Gispen
Incorporation of [3H] leucine into brain stem protein fractions: the effect of a behaviorally active, N-terminal fragment of ACTH in hypophysectomized rats.
Neurobiology 1975;5(6):355-68.
1975: Maarten E A Reith; P Schotman; W H Gispen
Effects of behaviorally active ACTH analogs on brain protein metabolism.
Progress in brain research 1975;42():195-200.
1974: Maarten E A Reith; P Schotman; W H Gispen
Hypophysectomy, ACTH1-10 and in vitro protein synthesis in rat brain stem slices.
Brain research 1974;81(3):571-5.