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David Rekosh

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Benson Chuks Iweriebor; Tracy Masebe; Lufuno Grace Mavhandu; Jeffrey M Mphahlele; David Rekosh; Marie-Louise Hammarskjold; Pascal Obong Bessong
Molecular epidemiology of HIV in two highly endemic areas of northeastern South Africa.
John H Coyle; Yeou-cherng Bor; David Rekosh; Marie-Louise Hammarskjold
The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway.
Myles H Hammarskjold; David Rekosh
A long-awaited structure is rev-ealed.

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All Publications

2012: Benson Chuks Iweriebor; Tracy Masebe; Lufuno Grace Mavhandu; Jeffrey M Mphahlele; David Rekosh; Marie-Louise Hammarskjold; Pascal Obong Bessong
Molecular epidemiology of HIV in two highly endemic areas of northeastern South Africa.
Archives of virology 2012;157(3):455-65.
2011: John H Coyle; Yeou-cherng Bor; David Rekosh; Marie-Louise Hammarskjold
The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway.
RNA (New York, N.Y.) 2011;17(7):1344-56.
2011: Myles H Hammarskjold; David Rekosh
A long-awaited structure is rev-ealed.
Viruses 2011;3(5):484-92.
2011: Deidra Shuck-Lee; Hua Chang; Emily A Sloan; Marie-Louise Hammarskjold; David Rekosh
Single-nucleotide changes in the HIV Rev-response element mediate resistance to compounds that inhibit Rev function.
Journal of virology 2011;85(8):3940-9.
2009: Michael D Moore; Olga Nikolaitchik; Jianbo Chen; Marie-Louise Hammarskjöld; David Rekosh; Wei-Shau Hu
Probing the HIV-1 genomic RNA trafficking pathway and dimerization by genetic recombination and single virion analyses.
PLoS pathogens 2009;5(10):e1000627.
2009: Alex M Ward; David Rekosh; Marie-Louise Hammarskjold
Trafficking through the Rev/RRE pathway is essential for efficient inhibition of human immunodeficiency virus type 1 by an antisense RNA derived from the envelope gene.
Journal of virology 2009;83(2):940-52.
2008: Michal Legiewicz; Christopher S Badorrek; Kevin B Turner; Daniele Fabris; Tiffany E Hamm; David Rekosh; Marie-Louise Hammarskjöld; Stuart F J Le Grice
Resistance to RevM10 inhibition reflects a conformational switch in the HIV-1 Rev response element.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14365-70.
2008: Deidra Shuck-Lee; Fei Fei Chen; Ryan Willard; Sharmila Raman; Roger Ptak; Marie-Louise Hammarskjold; David Rekosh
Heterocyclic compounds that inhibit Rev-RRE function and human immunodeficiency virus type 1 replication.
Antimicrobial agents and chemotherapy 2008;52(9):3169-79.
2008: Kevin C Olivieri; Robert M Scoggins; Brooks Broderick; Maria L C Powell; Melissa A Alexander; Marie-Louise Hammarskjöld; David Rekosh; David Camerini
Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142.
Retrovirology 2008;5():42.
2007: Melissa Soares Medeiros; Erico Antônio Gomes Arruda; Richard Littleton Guerrant; Christopher Brown; Marie-Louise Hammarskjold; David Rekosh; Aldo A M Lima
Genotype testing and antiretroviral resistance profiles from HIV-1 patients experiencing therapeutic failure in northeast Brazil.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2007;11(4):390-4.
2007: Jennifer E Swartz; Yeou-cherng Bor; Yukiko Misawa; David Rekosh; Marie-Louise Hammarskjold
The shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a constitutive transport element.
The Journal of biological chemistry 2007;282(27):19844-53.
2007: Kevin Olivieri; Robert M Scoggins; Yeou-cherng Bor; Aprille Matthews; David Mark; James R Taylor; David Chernauskas; Marie-Louise Hammarskjöld; David Rekosh; David Camerini
The envelope gene is a cytopathic determinant of CCR5 tropic HIV-1.
Virology 2007;358(1):23-38.
2006: Ying Li; Yeou-cherng Bor; Yukiko Misawa; Yuming Xue; David Rekosh; Marie-Louise Hammarskjöld
An intron with a constitutive transport element is retained in a Tap messenger RNA.
Nature 2006;443(7108):234-7.
2006: Yeou-cherng Bor; Jennifer Swartz; Avril Morrison; David Rekosh; Michael Ladomery; Marie-Louise Hammarskjöld
The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron.
Genes & development 2006;20(12):1597-608.
2006: Lyne Lévesque; Yeou-cherng Bor; Leah H Matzat; Li Jin; Stephen Berberoglu; David Rekosh; Marie-Louise Hammarskjöld; Bryce M Paschal
Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex.
Molecular biology of the cell 2006;17(2):931-43.
2004: Melissa Alexander; Yeou-cherng Bor; Kodi S Ravichandran; Marie-Louise Hammarskjöld; David Rekosh
Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity.
Journal of virology 2004;78(4):1685-96.
2003: Li Jin; Brian W Guzik; Yeou-cherng Bor; David Rekosh; Marie-Louise Hammarskjöld
Tap and NXT promote translation of unspliced mRNA.
Genes & development 2003;17(24):3075-86.
2003: Cay M Mierisch; Heather A Wilson; Maria A Turner; Todd Milbrandt; Lionel Berthoux; Marie-Louise Hammarskjöld; David Rekosh; Gary Balian; David R Diduch
Chondrocyte transplantation into articular cartilage defects with use of calcium alginate: the fate of the cells.
The Journal of bone and joint surgery. American volume 2003;85-A(9):1757-67.
2003: Todd Milbrandt; Lionel Berthoux; Vernon Christenson; Clark Baumbusch; David Rekosh; Gary Balian; David R Diduch
Tracing transduced cells in osteochondral defects.
Journal of pediatric orthopedics 2003;23(4):430-6.
2003: John H Coyle; Brian W Guzik; Yeou-cherng Bor; Li Jin; Lucia Eisner-Smerage; Stephen J Taylor; David Rekosh; Marie-Louise Hammarskjöld
Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.
Molecular and cellular biology 2003;23(1):92-103.
2001: Lyne Lévesque; Brian W Guzik; Tinglu Guan; J Coyle; Ben E Black; David Rekosh; Marie-Louise Hammarskjöld; Bryce M Paschal
RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complex.
The Journal of biological chemistry 2001;276(48):44953-62.
2001: Nathalie CHAZAL; G Singer; C Aiken; Marie-Louise Hammarskjöld; David Rekosh
Human immunodeficiency virus type 1 particles pseudotyped with envelope proteins that fuse at low pH no longer require Nef for optimal infectivity.
Journal of virology 2001;75(8):4014-8.
2001: Brian W Guzik; L Levesque; S Prasad; Yeou-cherng Bor; Ben E Black; Bryce M Paschal; David Rekosh; Marie-Louise Hammarskjöld
NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells.
Molecular and cellular biology 2001;21(7):2545-54.
2001: Scott F Walk; M Alexander; Bernhard Maier; Marie-Louise Hammarskjold; David Rekosh; Kodi S Ravichandran
Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation.
Journal of virology 2001;75(2):834-43.
1999: T E Hamm; David Rekosh; Marie-Louise Hammarskjöld
Selection and characterization of human immunodeficiency virus type 1 mutants that are resistant to inhibition by the transdominant negative RevM10 protein.
Journal of virology 1999;73(7):5741-7.
1999: C Helga-Maria; Marie-Louise Hammarskjöld; David Rekosh
An intact TAR element and cytoplasmic localization are necessary for efficient packaging of human immunodeficiency virus type 1 genomic RNA.
Journal of virology 1999;73(5):4127-35.
1997: A E Pasquinelli; Robert Ernst; E Lund; Christian grimm, Prof Dr. Phil. Nat.; Maria L Zapp; David Rekosh; Marie-Louise Hammarskjöld; JE Dahlberg
The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway.
The EMBO journal 1997;16(24):7500-10.
1997: N Srinivasakumar; Nathalie CHAZAL; C Helga-Maria; S Prasad; Marie-Louise Hammarskjöld; David Rekosh
The effect of viral regulatory protein expression on gene delivery by human immunodeficiency virus type 1 vectors produced in stable packaging cell lines.
Journal of virology 1997;71(8):5841-8.
1997: Miroslav Dundr; U. Thomas Meier; N Lewis; David Rekosh; Marie-Louise Hammarskjöld; Mark O J Olson
A class of nonribosomal nucleolar components is located in chromosome periphery and in nucleolus-derived foci during anaphase and telophase.
Chromosoma 1997;105(7-8):407-17.
1997: Robert Ernst; M Bray; David Rekosh; Marie-Louise Hammarskjold
Secondary structure and mutational analysis of the Mason-Pfizer monkey virus RNA constitutive transport element.
RNA (New York, N.Y.) 1997;3(2):210-22.
1997: Robert Ernst; M Bray; David Rekosh; Marie-Louise Hammarskjöld
A structured retroviral RNA element that mediates nucleocytoplasmic export of intron-containing RNA.
Molecular and cellular biology 1997;17(1):135-44.
1996: Miroslav Dundr; Gregory H Leno; N Lewis; David Rekosh; M L Hammarskjöid; Mark O J Olson
Location of the HIV-1 Rev protein during mitosis: inactivation of the nuclear export signal alters the pathway for postmitotic reentry into nucleoli.
Journal of cell science 1996;109 ( Pt 9)():2239-51.
1995: N Srinivasakumar; Marie-Louise Hammarskjöld; David Rekosh
Characterization of deletion mutations in the capsid region of human immunodeficiency virus type 1 that affect particle formation and Gag-Pol precursor incorporation.
Journal of virology 1995;69(10):6106-14.
1995: R D Berkowitz; Marie-Louise Hammarskjöld; C Helga-Maria; David Rekosh; Stephen P Goff
5' regions of HIV-1 RNAs are not sufficient for encapsidation: implications for the HIV-1 packaging signal.
Virology 1995;212(2):718-23.
1995: Miroslav Dundr; Gregory H Leno; Marie-Louise Hammarskjöld; David Rekosh; C Helga-Maria; Mark O J Olson
The roles of nucleolar structure and function in the subcellular location of the HIV-1 Rev protein.
Journal of cell science 1995;108 ( Pt 8)():2811-23.
1995: M J Orsini; A N Thakur; W W Andrews; Marie-Louise Hammarskjöld; David Rekosh
Expression and purification of the HIV type 1 Rev protein produced in Escherichia coli and its use in the generation of monoclonal antibodies.
AIDS research and human retroviruses 1995;11(8):945-53.
1995: H Mei; H Hirai; M Tanaka; Z Hong; David Rekosh; Philip T LoVerde
Schistosoma mansoni: cloning and characterization of a gene encoding cytosolic Cu/Zn superoxide dismutase.
Experimental parasitology 1995;80(2):250-9.
1994: Johnson Mak; M Jiang; Mark A Wainberg; Marie-Louise Hammarskjöld; David Rekosh; Lawrence Kleiman
Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles.
Journal of virology 1994;68(4):2065-72.
1994: M Bray; S Prasad; J W Dubay; Eric Hunter; K T Jeang; David Rekosh; Marie-Louise Hammarskjöld
A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1256-60.
1994: Marie-Louise Hammarskjöld; H Li; David Rekosh; S Prasad
Human immunodeficiency virus env expression becomes Rev-independent if the env region is not defined as an intron.
Journal of virology 1994;68(2):951-8.
1993: A J Smith; N Srinivasakumar; Marie-Louise Hammarskjöld; David Rekosh
Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles.
Journal of virology 1993;67(4):2266-75.
1993: Z Hong; Philip T LoVerde; A Thakur; Marie-Louise Hammarskjöld; David Rekosh
Schistosoma mansoni: a Cu/Zn superoxide dismutase is glycosylated when expressed in mammalian cells and localizes to a subtegumental region in adult schistosomes.
Experimental parasitology 1993;76(2):101-14.
1992: Z Hong; Philip T LoVerde; Marie-Louise Hammarskjöld; David Rekosh
Schistosoma mansoni: cloning of a complementary DNA encoding a cytosolic Cu/Zn superoxide dismutase and high-yield expression of the enzymatically active gene product in Escherichia coli.
Experimental parasitology 1992;75(3):308-22.
1992: Z Hong; Daniel J Kosman; A Thakur; David Rekosh; Philip T LoVerde
Identification and purification of a second form of Cu/Zn superoxide dismutase from Schistosoma mansoni.
Infection and immunity 1992;60(9):3641-51.
1992: L L Chen; David Rekosh; Philip T LoVerde
Schistosoma mansoni p48 eggshell protein gene: characterization, developmentally regulated expression and comparison to the p14 eggshell protein gene.
Molecular and biochemical parasitology 1992;52(1):39-52.
1991: L D Spotila; David Rekosh; Philip T LoVerde
Polymorphic repeated DNA element in the genome of Schistosoma mansoni.
Molecular and biochemical parasitology 1991;48(1):117-20.
1991: P M Mertz; L A Bobek; David Rekosh; Philip T LoVerde
Schistosoma haematobium and S. japonicum: analysis of the ribosomal RNA genes and determination of the "gap" boundaries and sequences.
Experimental parasitology 1991;73(2):137-49.
1991: H Xu; David Rekosh; W Andrews; G I Higashi; L Nicholson; Philip T LoVerde
Schistosoma mansoni tropomyosin: production and purification of the recombinant protein and studies on its immunodiagnostic potential.
The American journal of tropical medicine and hygiene 1991;45(1):121-31.
1991: L A Bobek; David Rekosh; Philip T LoVerde
Schistosoma japonicum: analysis of eggshell protein genes, their expression, and comparison with similar genes from other schistosomes.
Experimental parasitology 1991;72(4):381-90.
1991: H van Keulen; P M Mertz; Philip T LoVerde; H Shi; David Rekosh
Characterization of a 54-nucleotide gap region in the 28S rRNA gene of Schistosoma mansoni.
Molecular and biochemical parasitology 1991;45(2):205-14.
1990: X B Lu; J Heimer; David Rekosh; Marie-Louise Hammarskjöld
U1 small nuclear RNA plays a direct role in the formation of a rev-regulated human immunodeficiency virus env mRNA that remains unspliced.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7598-602.
1990: A J Smith; M I Cho; Marie-Louise Hammarskjöld; David Rekosh
Human immunodeficiency virus type 1 Pr55gag and Pr160gag-pol expressed from a simian virus 40 late replacement vector are efficiently processed and assembled into viruslike particles.
Journal of virology 1990;64(6):2743-50.
1990: N Lewis; J Williams; David Rekosh; Marie-Louise Hammarskjöld
Identification of a cis-acting element in human immunodeficiency virus type 2 (HIV-2) that is responsive to the HIV-1 rev and human T-cell leukemia virus types I and II rex proteins.
Journal of virology 1990;64(4):1690-7.
1989: Marie-Louise Hammarskjöld; David Rekosh
The molecular biology of the human immunodeficiency virus.
Biochimica et biophysica acta 1989;989(3):269-80.
1989: H Xu; S Miller; H van Keulen; M R Wawrzynski; David Rekosh; Philip T LoVerde
Schistosoma mansoni tropomyosin: cDNA characterization, sequence, expression, and gene product localization.
Experimental parasitology 1989;69(4):373-92.
1989: S Miller; David Rekosh; Philip T LoVerde
Schistosoma mansoni: identification and characterization of schistosomula polypeptides.
Experimental parasitology 1989;69(3):249-62.
1989: Marie-Louise Hammarskjöld; J Heimer; B Hammarskjöld; I Sangwan; L Albert; David Rekosh
Regulation of human immunodeficiency virus env expression by the rev gene product.
Journal of virology 1989;63(5):1959-66.
1989: L D Spotila; H Hirai; David Rekosh; Philip T LoVerde
A retroposon-like short repetitive DNA element in the genome of the human blood fluke, Schistosoma mansoni.
Chromosoma 1989;97(6):421-8.
1989: L A Bobek; Philip T LoVerde; David Rekosh
Schistosoma haematobium: analysis of eggshell protein genes and their expression.
Experimental parasitology 1989;68(1):17-30.
1989: Philip T LoVerde; David Rekosh; L A Bobek
Developmentally regulated gene expression in Schistosoma.
Experimental parasitology 1989;68(1):116-20.
1988: M C Simurda; H van Keulen; David Rekosh; Philip T LoVerde
Schistosoma mansoni: identification and analysis of an mRNA and a gene encoding superoxide dismutase (Cu/Zn).
Experimental parasitology 1988;67(1):73-84.
1988: L A Bobek; David Rekosh; Philip T LoVerde
Small gene family encoding an eggshell (chorion) protein of the human parasite Schistosoma mansoni.
Molecular and cellular biology 1988;8(8):3008-16.
1988: M B Nelson; T F Murphy; H van Keulen; David Rekosh; M A Apicella
Studies on P6, an important outer-membrane protein antigen of Haemophilus influenzae.
Reviews of infectious diseases 1988;10 Suppl 2():S331-6.
1988: M B Nelson; M A Apicella; T F Murphy; H Vankeulen; L D Spotila; David Rekosh
Cloning and sequencing of Haemophilus influenzae outer membrane protein P6.
Infection and immunity 1988;56(1):128-34.
1988: David Rekosh; A Nygren; P Flodby; Marie-Louise Hammarskjöld; H Wigzell
Coexpression of human immunodeficiency virus envelope proteins and tat from a single simian virus 40 late replacement vector.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(2):334-8.
1987: R J Gregoire; M H Shi; David Rekosh; Philip T LoVerde
Protective monoclonal antibodies from mice vaccinated or chronically infected with Schistosoma mansoni that recognize the same antigens.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(11):3792-801.
1987: L D Spotila; David Rekosh; J M Boucher; Philip T LoVerde
A cloned DNA probe identifies the sex of Schistosoma mansoni cercariae.
Molecular and biochemical parasitology 1987;26(1-2):17-20.
1986: L Bobek; David Rekosh; H van Keulen; Philip T LoVerde
Characterization of a female-specific cDNA derived from a developmentally regulated mRNA in the human blood fluke Schistosoma mansoni.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(15):5544-8.
1985: H van Keulen; Philip T LoVerde; L A Bobek; David Rekosh
Organization of the ribosomal RNA genes in Schistosoma mansoni.
Molecular and biochemical parasitology 1985;15(2):215-30.