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José Remacle

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Anatomy

Physiology

Devices

Oligonucleotide Array Sequence Analysis

Chemicals & Drugs

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Publications

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Sébastien Vankoningsloo; Françoise de Longueville; Stéphanie Evrard; Pierre Rahier; Andrée Houbion; Antoine Fattaccioli; Mélanie Gastellier; José Remacle; Martine Raes; Patricia Renard; Thierry Arnould
Gene expression silencing with 'specific' small interfering RNA goes beyond specificity - a study of key parameters to take into account in the onset of small interfering RNA off-target effects.
S Burteau; Pierre Bogaerts; Ricardo de Mendonça; Leonid M Irenge; Catherine Berhin; J Hiffe; N de San; P Beyne; Sandrine Hamels; Youri Glupczynski; Marc Jean Struelens; Jean-Luc Gala; José Remacle
Design and validation of a low density array (Nosochip) for the detection and identification of the main pathogenic bacteria and fungi responsible for nosocomial pneumonia.
Florence Debacq-Chainiaux; Céline Borlon; B De Hertogh; José Remacle; Pierre-Yves Morvan; R Vallée; Olivier Toussaint
Identification of potential anti-photoageing algal compounds using an in-vitro model of photoageing.

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All Publications

2008: Sébastien Vankoningsloo; Françoise de Longueville; Stéphanie Evrard; Pierre Rahier; Andrée Houbion; Antoine Fattaccioli; Mélanie Gastellier; José Remacle; Martine Raes; Patricia Renard; Thierry Arnould
Gene expression silencing with 'specific' small interfering RNA goes beyond specificity - a study of key parameters to take into account in the onset of small interfering RNA off-target effects.
The FEBS journal 2008;275(11):2738-53.
2008: S Burteau; Pierre Bogaerts; Ricardo de Mendonça; Leonid M Irenge; Catherine Berhin; J Hiffe; N de San; P Beyne; Sandrine Hamels; Youri Glupczynski; Marc Jean Struelens; Jean-Luc Gala; José Remacle
Design and validation of a low density array (Nosochip) for the detection and identification of the main pathogenic bacteria and fungi responsible for nosocomial pneumonia.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2008;27(1):17-27.
2006: Florence Debacq-Chainiaux; Céline Borlon; B De Hertogh; José Remacle; Pierre-Yves Morvan; R Vallée; Olivier Toussaint
Identification of potential anti-photoageing algal compounds using an in-vitro model of photoageing.
The Journal of pharmacy and pharmacology 2006;58(12):1577-83.
2006: Stéphanie Zdanov; Florence Debacq-Chainiaux; José Remacle; Olivier Toussaint
Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts.
FEBS letters 2006;580(27):6455-63.
2006: Thomas Efferth; Jean-Pierre Gillet; Axel Sauerbrey; Felix Zintl; Vincent Bertholet; Françoise de Longueville; José Remacle; Daniel Steinbach
Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia.
Molecular cancer therapeutics 2006;5(8):1986-94.
2006: Daniel Steinbach; Jean-Pierre Gillet; Axel Sauerbrey; Bernd Gruhn; Kristin Dawczynski; Vincent Bertholet; Françoise de Longueville; Felix Zintl; José Remacle; Thomas Efferth
ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(14 Pt 1):4357-63.
2006: Stéphanie Zdanov; José Remacle; Olivier Toussaint
Establishment of H2O2-induced premature senescence in human fibroblasts concomitant with increased cellular production of H2O2.
Annals of the New York Academy of Sciences 2006;1067():210-6.
2006: Jean-Pierre Gillet; Françoise de Longueville; José Remacle
DualChip microarray as a new tool in cancer research.
Expert review of molecular diagnostics 2006;6(3):295-306.
2006: Sébastien Vankoningsloo; Aurélia De Pauw; Andrée Houbion; Silvia Tejerina; Catherine Demazy; Françoise de Longueville; Vincent Bertholet; Patricia Renard; José Remacle; Paul Holvoet; Martine Raes; Thierry Arnould
CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes.
Journal of cell science 2006;119(Pt 7):1266-82.
2006: Gerhard A Blab; Laurent Cognet; Stéphane Berciaud; Isabelle Alexandre; Dieter Husar; José Remacle; Brahim Lounis
Optical readout of gold nanoparticle-based DNA microarrays without silver enhancement.
Biophysical journal 2006;90(1):L13-5.
2005: Nathalie Zammatteo; Caroline Davril; Francis Brasseur; Sandrine Hamels; Etienne De Plaen; Thierry Boon; José Remacle
Unambiguous identification of the expressed MAGE-A genes on a DNA microarray.
Clinical chemistry 2005;51(12):2420-1.
2005: Françoise de Longueville; Marc Lacroix; Anna-Maria Barbuto; Vincent Bertholet; dominique Gallo; Denis Larsimont; Laurence Marcq; Nathalie Zammatteo; Sophie Boffe; Guy Leclercq; José Remacle
Molecular characterization of breast cancer cell lines by a low-density microarray.
International journal of oncology 2005;27(4):881-92.
2005: Thierry Pascal; Florence Debacq-Chainiaux; Aline Chrétien; Coralie Bastin; Anne-France Dabée; Vincent Bertholet; José Remacle; Olivier Toussaint
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays.
FEBS letters 2005;579(17):3651-9.
2005: Florence Debacq-Chainiaux; Céline Borlon; Thierry Pascal; Véronique Royer; François Eliaers; Noelle Ninane; Géraldine Carrard; Bertrand Friguet; Françoise de Longueville; Sophie Boffe; José Remacle; Olivier Toussaint
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.
Journal of cell science 2005;118(Pt 4):743-58.
2004: Jean-Pierre Gillet; Thomas Efferth; Daniel Steinbach; Jacques Hamels; Françoise de Longueville; Vincent Bertholet; José Remacle
Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes.
Cancer research 2004;64(24):8987-93.
2004: João Pedro de Magalhães; Florence Chainiaux; Françoise de Longueville; Véronique Mainfroid; Valérie Migeot; Laurence Marcq; José Remacle; Michel Salmon; Olivier Toussaint
Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase.
Experimental gerontology 2004;39(9):1379-89.
2004: João Pedro de Magalhães; Valérie Migeot; Véronique Mainfroid; Françoise de Longueville; José Remacle; Olivier Toussaint
No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.
Annals of the New York Academy of Sciences 2004;1019():375-8.
2004: Françoise de Longueville; Vincent Bertholet; José Remacle
DNA microarrays as a tool in toxicogenomics.
Combinatorial chemistry & high throughput screening 2004;7(3):207-11.
2004: Jean-Pascal Piret; Thierry Arnould; Bruno Fuks; Pierre Chatelain; José Remacle; Carine Michiels
Caspase activation precedes PTP opening in TNF-alpha-induced apoptosis in L929 cells.
Mitochondrion 2004;3(5):261-78.
2004: Jean-Pascal Piret; Thierry Arnould; Bruno Fuks; Pierre Chatelain; José Remacle; Carine Michiels
Mitochondria permeability transition-dependent tert-butyl hydroperoxide-induced apoptosis in hepatoma HepG2 cells.
Biochemical pharmacology 2004;67(4):611-20.
2004: Michel Salmon; Jérémie Dedessus Le Moutier; Frédéric Wenders; Sophie Chiarizia; François Eliaers; José Remacle; Véronique Royer; Thierry Pascal; Olivier Toussaint
Role of the PLA2-independent peroxiredoxin VI activity in the survival of immortalized fibroblasts exposed to cytotoxic oxidative stress.
FEBS letters 2004;557(1-3):26-32.
2003: Françoise de Longueville; Franck A Atienzar; Laurence Marcq; Simon Dufrane; Stéphanie Evrard; Lydia Wouters; Florence Leroux; Vincent Bertholet; Brigitte Gerin; Rhys Whomsley; Thierry Arnould; José Remacle; Michael Canning
Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes.
Toxicological sciences : an official journal of the Society of Toxicology 2003;75(2):378-92.
2003: Georgina Meneses-Lorente; Françoise de Longueville; Sofia Dos Santos-Mendes; Timothy P Bonnert; Andrew Jack; Stéphanie Evrard; Vincent Bertholet; Andrew Pike; Paul Scott-Stevens; José Remacle; Bindi Sohal
An evaluation of a low-density DNA microarray using cytochrome P450 inducers.
Chemical research in toxicology 2003;16(9):1070-7.
2003: Christophe Frippiat; José Remacle; Olivier Toussaint
Down-regulation and decreased activity of cyclin-dependent kinase 2 in H2O2-induced premature senescence.
The international journal of biochemistry & cell biology 2003;35(2):246-54.
2003: Jean-François Dierick; Frédéric Wenders; Florence Chainiaux; José Remacle; Aron B Fisher; Olivier Toussaint
Retrovirally mediated overexpression of peroxiredoxin VI increases the survival of WI-38 human diploid fibroblasts exposed to cytotoxic doses of tert-butylhydroperoxide and UVB.
Biogerontology 2003;4(3):125-31.
2002: Christophe Frippiat; Janique Dewelle; José Remacle; Olivier Toussaint
Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts.
Free radical biology & medicine 2002;33(10):1334-46.
2002: Florence Chainiaux; José Remacle; Olivier Toussaint
Exposure of human skin diploid fibroblasts to repeated subcytotoxic doses of ultraviolet-B induces the overexpression of transforming growth factor-beta1 mRNA.
Annals of the New York Academy of Sciences 2002;973():44-8.
2002: Olivier Toussaint; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Stéphanie Zdanov; Joao Pedro Magalhaes; Véronique Royer; Florence Chainiaux
From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing.
The international journal of biochemistry & cell biology 2002;34(11):1415-29.
2002: Florence Chainiaux; Joao Pedro Magalhaes; François Eliaers; José Remacle; Olivier Toussaint
UVB-induced premature senescence of human diploid skin fibroblasts.
The international journal of biochemistry & cell biology 2002;34(11):1331-9.
2002: Gaetan Michel; Emmanuel Minet; Denis Mottet; José Remacle; Carine Michiels
Site-directed mutagenesis studies of the hypoxia-inducible factor-1alpha DNA-binding domain.
Biochimica et biophysica acta 2002;1578(1-3):73-83.
2002: Jean-François Dierick; François Eliaers; José Remacle; Martine Raes; Stephen Fey; Peter Mose Larsen; Olivier Toussaint
Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence.
Biochemical pharmacology 2002;64(5-6):1011-7.
2002: Olivier Toussaint; Véronique Royer; Michel Salmon; José Remacle
Stress-induced premature senescence and tissue ageing.
Biochemical pharmacology 2002;64(5-6):1007-9.
2002: Isabelle Alexandre; Y Houbion; J Collet; Sandrine Hamels; J Demarteau; Jean-Luc Gala; José Remacle
Compact disc with both numeric and genomic information as DNA microarray platform.
BioTechniques 2002;33(2):435-6, 438-9.
2002: João Pedro de Magalhães; Florence Chainiaux; José Remacle; Olivier Toussaint
Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts.
FEBS letters 2002;523(1-3):157-62.
2002: Françoise de Longueville; dominic Surry; Georgina Meneses-Lorente; Vincent Bertholet; Valérie Talbot; Stéphanie Evrard; Nathalie Chandelier; Andrew Pike; Phil Worboys; Jean Paul Rasson; Béatrice Le Bourdellès; José Remacle
Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray.
Biochemical pharmacology 2002;64(1):137-49.
2002: Carine Michiels; Najat Bouaziz; José Remacle
Role of the endothelium and blood stasis in the development of varicose veins.
International angiology : a journal of the International Union of Angiology 2002;21(2 Suppl 1):18-25.
2002: Jean-François Dierick; Marc Dieu; José Remacle; Martine Raes; Peter Roepstorff; Olivier Toussaint
Proteomics in experimental gerontology.
Experimental gerontology 2002;37(5):721-34.
2002: Olivier Toussaint; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Véronique Royer; Florence Chainiaux
Approach of evolutionary theories of ageing, stress, senescence-like phenotypes, calorie restriction and hormesis from the view point of far-from-equilibrium thermodynamics.
Mechanisms of ageing and development 2002;123(8):937-46.
2002: Najat Bouaziz; Martine Redon; Luc Quéré; José Remacle; Carine Michiels
Mitochondrial respiratory chain as a new target for anti-ischemic molecules.
European journal of pharmacology 2002;441(1-2):35-45.
2002: Carine Michiels; Najat Bouaziz; José Remacle
Role of the endothelium and blood stasis in the appearance of varicose veins.
International angiology : a journal of the International Union of Angiology 2002;21(1):1-8.
2002: Olivier Toussaint; Patrick Dumont; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Joao Pedro Magalhaes; Stéphanie Zdanov; Florence Chainiaux
Stress-induced premature senescence or stress-induced senescence-like phenotype: one in vivo reality, two possible definitions?
TheScientificWorldJournal 2002;2():230-47.
2002: Thierry Arnould; Sébastien Vankoningsloo; Patricia Renard; Andrée Houbion; Noelle Ninane; Catherine Demazy; José Remacle; Martine Raes
CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation.
The EMBO journal 2002;21(1-2):53-63.
2002: Nathalie Zammatteo; Sandrine Hamels; Françoise de Longueville; Isabelle Alexandre; Jean-Luc Gala; Francis Brasseur; José Remacle
New chips for molecular biology and diagnostics.
Biotechnology annual review 2002;8():85-101.
2002: Olivier Toussaint; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Véronique Royer; Joao Pedro Magalhacs; Stéphanie Zdanov; Florence Chainiaux
Stress-induced premature senescence: from biomarkers to likeliness of in vivo occurrence.
Biogerontology 2002;3(1-2):13-7.
2002: Patrick Dumont; Florence Chainiaux; François Eliaers; Chariklia Petropoulou; José Remacle; Claudia Koch-Brandt; Efstathios S Gonos; Olivier Toussaint
Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide.
Cell stress & chaperones 2002;7(1):23-35.
2002: Gwénaëlle Bestel-Corre; Eliane Dumas-Gaudot; Véréna Poinsot; Marc Dieu; Jean-François Dierick; Tuinen Diederik van; José Remacle; Vivienne Gianinazzi-Pearson; Silvio Gianinazzi
Proteome analysis and identification of symbiosis-related proteins from Medicago truncatula Gaertn. by two-dimensional electrophoresis and mass spectrometry.
Electrophoresis 2002;23(1):122-37.
2002: Nathalie Zammatteo; Laurence Lockman; Francis Brasseur; Etienne De Plaen; Christophe Lurquin; Pierre-Emmanuel Lobert; Sandrine Hamels; Thierry Boon; José Remacle
DNA microarray to monitor the expression of MAGE-A genes.
Clinical chemistry 2002;48(1):25-34.
2001: Sandrine Hamels; Jean-Luc Gala; S Dufour; P Vannuffel; Nathalie Zammatteo; José Remacle
Consensus PCR and microarray for diagnosis of the genus Staphylococcus, species, and methicillin resistance.
BioTechniques 2001;31(6):1364-6, 1368, 1370-2.
2001: Florence Lebon; Marie Ledecq; M Dieu; Catherine Demazy; José Remacle; René Lapouyade; O Kahn; François Durant
Synthesis and structural analysis of the copper(II) complexes of N2-(2-pyridylmethyl)-2-pyridinecarboxamide.
Journal of inorganic biochemistry 2001;86(2-3):547-54.
2001: Patrick Dumont; Véronique Royer; Thierry Pascal; Jean-François Dierick; Florence Chainiaux; Christophe Frippiat; J P de Magalhaes; François Eliaers; José Remacle; Olivier Toussaint
Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress-induced premature senescence.
FEBS letters 2001;502(3):109-12.
2001: Isabelle Alexandre; Sandrine Hamels; S Dufour; J Collet; Nathalie Zammatteo; Françoise de Longueville; Jean-Luc Gala; José Remacle
Colorimetric silver detection of DNA microarrays.
Analytical biochemistry 2001;295(1):1-8.
2001: Thierry Arnould; R Thibaut-Vercruyssen; Najat Bouaziz; Marc Dieu; José Remacle; Carine Michiels
PGF(2alpha), a prostanoid released by endothelial cells activated by hypoxia, is a chemoattractant candidate for neutrophil recruitment.
The American journal of pathology 2001;159(1):345-57.
2001: Olivier Toussaint; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Joao Pedro Magalhaes; F Chainaux
Hormesis: a quest for virtuality?
Human & experimental toxicology 2001;20(6):311-4; discussion 319-20.
2001: P Renard; Edouard Delaive; M Van Steenbrugge; José Remacle; Martine Raes
Is the effect of interleukin-1 on glutathione oxidation in cultured human fibroblasts involved in nuclear factor-kappaB activation?
Antioxidants & redox signaling 2001;3(2):329-40.
2001: I Ernest; Isabelle Alexandre; Nathalie Zammatteo; M Herman; Andrée Houbion; F De Leener; K Fransen; G van der Groen; José Remacle
Quantitative assay for group M (subtype A-H) and group O HIV-1 RNA detection in plasma.
Journal of virological methods 2001;93(1-2):1-14.
2001: Patricia Renard; I Ernest; Andrée Houbion; M Art; H Le Calvez; Martine Raes; José Remacle
Development of a sensitive multi-well colorimetric assay for active NFkappaB.
Nucleic acids research 2001;29(4):E21.
2001: Christophe Frippiat; Qin M Chen; Stéphanie Zdanov; Joao Pedro Magalhaes; José Remacle; Olivier Toussaint
Subcytotoxic H2O2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts.
The Journal of biological chemistry 2001;276(4):2531-7.
2001: N Berna; Thierry Arnould; José Remacle; Carine Michiels
Hypoxia-induced increase in intracellular calcium concentration in endothelial cells: role of the Na(+)-glucose cotransporter.
Journal of cellular biochemistry 2001;84(1):115-31.
2000: Gaetan Michel; Emmanuel Minet; I Ernest; IH Roland; François Durant; José Remacle; Carine Michiels
A model for the complex between the hypoxia-inducible factor-1 (HIF-1) and its consensus DNA sequence.
Journal of biomolecular structure & dynamics 2000;18(2):169-79.
2000: Christophe Frippiat; Qin M Chen; José Remacle; Olivier Toussaint
Cell cycle regulation in H(2)O(2)-induced premature senescence of human diploid fibroblasts and regulatory control exerted by the papilloma virus E6 and E7 proteins.
Experimental gerontology 2000;35(6-7):733-45.
2000: D Janssens; Edouard Delaive; Andrée Houbion; François Eliaers; José Remacle; Carine Michiels
Effect of venotropic drugs on the respiratory activity of isolated mitochondria and in endothelial cells.
British journal of pharmacology 2000;130(7):1513-24.
2000: Carine Michiels; Thierry Arnould; José Remacle
Endothelial cell responses to hypoxia: initiation of a cascade of cellular interactions.
Biochimica et biophysica acta 2000;1497(1):1-10.
2000: Patrick Dumont; M Burton; Qin M Chen; Christophe Frippiat; Thierry Pascal; Jean-François Dierick; François Eliaers; Florence Chainiaux; José Remacle; Olivier Toussaint
Human diploid fibroblasts display a decreased level of c-fos mRNA at 72 hours after exposure to sublethal H2O2 stress.
Annals of the New York Academy of Sciences 2000;908():306-9.
2000: Jean-François Dierick; Thierry Pascal; Florence Chainiaux; François Eliaers; José Remacle; Peter Mose Larsen; Peter Roepstorff; Olivier Toussaint
Transcriptome and proteome analysis in human senescent fibroblasts and fibroblasts undergoing premature senescence induced by repeated sublethal stresses.
Annals of the New York Academy of Sciences 2000;908():302-5.
2000: Olivier Toussaint; Patrick Dumont; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Florence Chainiaux; F Sluse; François Eliaers; José Remacle
Stress-induced premature senescence. Essence of life, evolution, stress, and aging.
Annals of the New York Academy of Sciences 2000;908():85-98.
2000: S Warnon; Nathalie Zammatteo; Isabelle Alexandre; C Hans; José Remacle
Colorimetric detection of the tuberculosis complex using cycling probe technology and hybridization in microplates.
BioTechniques 2000;28(6):1152-6, 1159-60.
2000: IH Roland; Emmanuel Minet; I Ernest; Thierry Pascal; Gaetan Michel; José Remacle; Carine Michiels
Identification of hypoxia-responsive messengers expressed in human microvascular endothelial cells using differential display RT-PCR.
European journal of biochemistry / FEBS 2000;267(12):3567-74.
2000: D Janssens; Edouard Delaive; José Remacle; Carine Michiels
Protection by bilobalide of the ischaemia-induced alterations of the mitochondrial respiratory activity.
Fundamental & clinical pharmacology 2000;14(3):193-201.
2000: A Gomez; A Mve-Obiang; B Vray; José Remacle; Karim Chemlal; Wayne M Meyers; Françoise Portaels; Pierre-Alain Fonteyne
Biochemical and genetic evidence for phospholipase C activity in Mycobacterium ulcerans.
Infection and immunity 2000;68(5):2995-7.
2000: Nathalie Zammatteo; L Jeanmart; Sandrine Hamels; S Courtois; P Louette; L Hevesi; José Remacle
Comparison between different strategies of covalent attachment of DNA to glass surfaces to build DNA microarrays.
Analytical biochemistry 2000;280(1):143-50.
2000: Emmanuel Minet; Gaetan Michel; José Remacle; Carine Michiels
Role of HIF-1 as a transcription factor involved in embryonic development, cancer progression and apoptosis (review).
International journal of molecular medicine 2000;5(3):253-9.
2000: Emmanuel Minet; Thierry Arnould; Gaetan Michel; IH Roland; Denis Mottet; Martine Raes; José Remacle; Carine Michiels
ERK activation upon hypoxia: involvement in HIF-1 activation.
FEBS letters 2000;468(1):53-8.
2000: Patrick Dumont; M Burton; Qin M Chen; Efstathios S Gonos; Christophe Frippiat; J B Mazarati; François Eliaers; José Remacle; Olivier Toussaint
Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast.
Free radical biology & medicine 2000;28(3):361-73.
2000: Olivier Toussaint; Patrick Dumont; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Florence Chainiaux; Joao Pedro Magalhaes; François Eliaers; José Remacle
Stress-induced premature senescence as alternative toxicological method for testing the long-term effects of molecules under development in the industry.
Biogerontology 2000;1(2):179-83.
2000: Christophe Frippiat; Jean-François Dierick; José Remacle; Olivier Toussaint
Consideration of heteroduplexes and homoduplexes for the quantification by competitive PCR of human mitochondrial DNA deletions with ageing of tissues and cells.
Biogerontology 2000;1(3):279-83.
1999: Najat Bouaziz; Carine Michiels; D Janssens; N Berna; François Eliaers; E Panconi; José Remacle
Effect of Ruscus extract and hesperidin methylchalcone on hypoxia-induced activation of endothelial cells.
International angiology : a journal of the International Union of Angiology 1999;18(4):306-12.
1999: A Mve-Obiang; José Remacle; J C Palomino; Andrée Houbion; Françoise Portaels
Growth and cytotoxic activity by Mycobacterium ulcerans in protein-free media.
FEMS microbiology letters 1999;181(1):153-7.
1999: Emmanuel Minet; Denis Mottet; Gaetan Michel; IH Roland; Martine Raes; José Remacle; Carine Michiels
Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction.
FEBS letters 1999;460(2):251-6.
1999: Emmanuel Minet; I Ernest; Gaetan Michel; IH Roland; José Remacle; Martine Raes; Carine Michiels
HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5'UTR.
Biochemical and biophysical research communications 1999;261(2):534-40.
1999: D Janssens; José Remacle; K Drieu; Carine Michiels
Protection of mitochondrial respiration activity by bilobalide.
Biochemical pharmacology 1999;58(1):109-19.
1999: D Janssens; Carine Michiels; G Guillaume; B Cuisinier; Y Louagie; José Remacle
Increase in circulating endothelial cells in patients with primary chronic venous insufficiency: protective effect of Ginkor Fort in a randomized double-blind, placebo-controlled clinical trial.
Journal of cardiovascular pharmacology 1999;33(1):7-11.
1998: Isabelle Alexandre; Nathalie Zammatteo; I Ernest; J M Ladriere; L Le; Sandrine Hamels; N Chandelier; B Vipond; José Remacle
Quantitative determination of CMV DNA using a combination of competitive PCR amplification and sandwich hybridization.
BioTechniques 1998;25(4):676-83.
1998: IH Roland; C Bougelet; Noelle Ninane; Thierry Arnould; Carine Michiels; José Remacle
Effect of hydroxyethylrutosides on hypoxial-induced neutrophil adherence to umbilical vein endothelium.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1998;12(4):375-81.
1998: Carine Michiels; Thierry Arnould; José Remacle
Role of PECAM-1 in the adherence of PMN to hypoxic endothelial cells.
Cell adhesion and communication 1998;5(5):367-74.
1998: Olivier Toussaint; S Y Fuchs; Z A Ronai; S Isoyama; N Yuko; Valeria Petronilli; Paolo Bernardi; Efstathios S Gonos; Patrick Dumont; José Remacle
Reciprocal relationships between the resistance to stresses and cellular aging.
Annals of the New York Academy of Sciences 1998;851():450-65.
1998: C Bougelet; IH Roland; Noelle Ninane; Thierry Arnould; José Remacle; Carine Michiels
Effect of aescine on hypoxia-induced neutrophil adherence to umbilical vein endothelium.
European journal of pharmacology 1998;345(1):89-95.
1998: Thierry Arnould; Carine Michiels; D Janssens; N Berna; José Remacle
Effect of Ginkor Fort on hypoxia-induced neutrophil adherence to human saphenous vein endothelium.
Journal of cardiovascular pharmacology 1998;31(3):456-63.
1997: Nathalie Zammatteo; Isabelle Alexandre; I Ernest; L Le; F Brancart; José Remacle
Comparison between microwell and bead supports for the detection of human cytomegalovirus amplicons by sandwich hybridization.
Analytical biochemistry 1997;253(2):180-9.
1997: Carine Michiels; Thierry Arnould; R Thibaut-Vercruyssen; Najat Bouaziz; D Janssens; José Remacle
Perfused human saphenous veins for the study of the origin of varicose veins: role of the endothelium and of hypoxia.
International angiology : a journal of the International Union of Angiology 1997;16(2):134-41.
1997: Isabelle Alexandre; Nathalie Zammatteo; P Moris; F Brancart; José Remacle
Comparison of three luminescent assays combined with a sandwich hybridization for the measurement of PCR-amplified human cytomegalovirus DNA.
Journal of virological methods 1997;66(1):113-22.
1997: P Renard; M D Zachary; C Bougelet; M E Mirault; G Haegeman; José Remacle; M Raes
Effects of antioxidant enzyme modulations on interleukin-1-induced nuclear factor kappa B activation.
Biochemical pharmacology 1997;53(2):149-60.
1997: D Delforge; B Devreese; Marc Dieu; Edouard Delaive; J Van Beeumen; José Remacle
Identification of lysine 74 in the pyruvate binding site of alanine dehydrogenase from Bacillus subtilis. Chemical modification with 2,4,6-trinitrobenzenesulfonic acid, n-succinimidyl 3-(2-pyridyldithio)propionate, and 5'-(p-(fluorosulfonyl)benzoyl)adenosine.
The Journal of biological chemistry 1997;272(4):2276-84.
1996: D Delforge; M Art; B Gillon; M Dieu; E Delaive; M Raes; José Remacle
Automated solid-phase synthesis of cyclic peptides bearing a side-chain tail designed for subsequent chemical grafting.
Analytical biochemistry 1996;242(2):180-6.
1996: Thierry Arnould; D Janssens; Carine Michiels; José Remacle
Effect of aescine on hypoxia-induced activation of human endothelial cells.
European journal of pharmacology 1996;315(2):227-33.
1996: Carine Michiels; Thierry Arnould; D Janssens; K Bajou; I Geron; José Remacle
Interactions between endothelial cells and smooth muscle cells after their activation by hypoxia. A possible etiology for venous disease.
International angiology : a journal of the International Union of Angiology 1996;15(2):124-30.
1996: D Janssens; Carine Michiels; Thierry Arnould; José Remacle
Effects of hydroxyethylrutosides on hypoxia-induced activation of human endothelial cells in vitro.
British journal of pharmacology 1996;118(3):599-604.
1996: Nathalie Zammatteo; C Girardeaux; D Delforge; J J Pireaux; José Remacle
Amination of polystyrene microwells: application to the covalent grafting of DNA probes for hybridization assays.
Analytical biochemistry 1996;236(1):85-94.
1996: José Remacle; P Renard
[Role of oxidative stress in aging].
Pathologie-biologie 1996;44(1):65-76.
1995: Thierry Arnould; Carine Michiels; D Janssens; E Delaive; José Remacle
Hypoxia induces PMN adherence to umbilical vein endothelium.
Cardiovascular research 1995;30(6):1009-16.
1995: Nathalie Zammatteo; P Moris; Isabelle Alexandre; D Vaira; J Piette; José Remacle
DNA probe hybridisation in microwells using a new bioluminescent system for the detection of PCR-amplified HIV-1 proviral DNA.
Journal of virological methods 1995;55(2):185-97.
1995: D Janssens; Carine Michiels; E Delaive; F Eliaers; K Drieu; José Remacle
Protection of hypoxia-induced ATP decrease in endothelial cells by ginkgo biloba extract and bilobalide.
Biochemical pharmacology 1995;50(7):991-9.
1995: José Remacle; M Raes; O Toussaint; P Renard; G Rao
Low levels of reactive oxygen species as modulators of cell function.
Mutation research 1995;316(3):103-22.
1995: O Toussaint; Carine Michiels; M Raes; José Remacle
Cellular aging and the importance of energetic factors.
Experimental gerontology 1995;30(1):1-22.
1994: Carine Michiels; M Raes; O Toussaint; José Remacle
Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress.
Free radical biology & medicine 1994;17(3):235-48.
1994: V Lecomte; I Knott; M Burton; José Remacle; M Raes
Cathepsin B and N-acetyl-beta-D-glucosaminidase in human synovial cells in culture: effects of interleukin-1.
Clinica chimica acta; international journal of clinical chemistry 1994;228(2):143-59.
1994: O Toussaint; A Houbion; José Remacle
Effects of modulations of the energetic metabolism on the mortality of cultured cells.
Biochimica et biophysica acta 1994;1186(3):209-20.
1994: Carine Michiels; F De Leener; Thierry Arnould; M Dieu; José Remacle
Hypoxia stimulates human endothelial cells to release smooth muscle cell mitogens: role of prostaglandins and bFGF.
Experimental cell research 1994;213(1):43-54.
1994: Thierry Arnould; Carine Michiels; José Remacle
Hypoxic human umbilical vein endothelial cells induce activation of adherent polymorphonuclear leukocytes.
Blood 1994;83(12):3705-16.
1994: O Toussaint; José Remacle
[Critical review of theories on cell aging. From Hayflick's basis concept to the concept of critical threshold of accumulation of errors].
Pathologie-biologie 1994;42(4):313-21.
1994: O Toussaint; José Remacle
[Arguments in favour of the concept of critical threshold of accumulation of errors in cell death. Qualities and limits of this concept in cell aging].
Pathologie-biologie 1994;42(4):305-11.
1994: I Knott; M Dieu; M Burton; A Houbion; José Remacle; M Raes
Induction of cyclooxygenase by interleukin 1: comparative study between human synovial cells and chondrocytes.
The Journal of rheumatology 1994;21(3):462-6.
1993: Carine Michiels; Thierry Arnould; D Janssens; Isabelle Alexandre; A Houbion; José Remacle
Effects of naftidrofuryl on hypoxia-induced activation and mortality of human endothelial cells.
The Journal of pharmacology and experimental therapeutics 1993;267(2):904-11.
1993: Philippe Corbisier; José Remacle
Influence of the energetic pattern of mitochondria in cell ageing.
Mechanisms of ageing and development 1993;71(1-2):47-58.
1993: Carine Michiels; Thierry Arnould; José Remacle
Hypoxia-induced activation of endothelial cells as a possible cause of venous diseases: hypothesis.
Angiology 1993;44(8):639-46.
1993: O Toussaint; A Houbion; José Remacle
Relationship between the critical level of oxidative stresses and the glutathione peroxidase activity.
Toxicology 1993;81(2):89-101.
1993: I Knott; M Dieu; M Burton; V Lecomte; José Remacle; M Raes
Differential effects of interleukin-1 alpha and beta on the arachidonic acid cascade in human synovial cells and chondrocytes in culture.
Agents and actions 1993;39(3-4):126-31.
1993: I Knott; M Raes; M Dieu; G Lenoir; M Burton; José Remacle
Routine prostaglandin assay by GC-MS in multiwell tissue culture plates: application to human synoviocytes and chondrocytes.
Analytical biochemistry 1993;210(2):360-5.
1993: Thierry Arnould; Carine Michiels; José Remacle
Increased PMN adherence on endothelial cells after hypoxia: involvement of PAF, CD18/CD11b, and ICAM-1.
The American journal of physiology 1993;264(5 Pt 1):C1102-10.
1993: Carine Michiels; Thierry Arnould; I Knott; M Dieu; José Remacle
Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia.
The American journal of physiology 1993;264(4 Pt 1):C866-74.
1993: D Delforge; Eric Depiereux; Xavier De Bolle; E Feytmans; José Remacle
Similarities between alanine dehydrogenase and the N-terminal part of pyridine nucleotide transhydrogenase and their possible implication in the virulence mechanism of Mycobacterium tuberculosis.
Biochemical and biophysical research communications 1993;190(3):1073-9.
1992: E Magonet; E Delaive; B Martin; José Remacle
The effect of intra- and intermolecular disulfide bonds after peptide grafting on the properties of yeast alcohol dehydrogenase.
Biochemistry international 1992;28(4):603-12.
1992: E Magonet; P Hayen; D Delforge; E Delaive; José Remacle
Importance of the structural zinc atom for the stability of yeast alcohol dehydrogenase.
The Biochemical journal 1992;287 ( Pt 2)():361-5.
1992: Carine Michiels; Thierry Arnould; A Houbion; José Remacle
Human umbilical vein endothelial cells submitted to hypoxia-reoxygenation in vitro: implication of free radicals, xanthine oxidase, and energy deficiency.
Journal of cellular physiology 1992;153(1):53-61.
1992: José Remacle; D Lambert; M Raes; E Pigeolet; Carine Michiels; O Toussaint
Importance of various antioxidant enzymes for cell stability. Confrontation between theoretical and experimental data.
The Biochemical journal 1992;286 ( Pt 1)():41-6.
1992: O Toussaint; A Houbion; José Remacle
Aging as a multi-step process characterized by a lowering of entropy production leading the cell to a sequence of defined stages. II. Testing some predictions on aging human fibroblasts in culture.
Mechanisms of ageing and development 1992;65(1):65-83.
1992: Thierry Arnould; Carine Michiels; Isabelle Alexandre; José Remacle
Effect of hypoxia upon intracellular calcium concentration of human endothelial cells.
Journal of cellular physiology 1992;152(1):215-21.
1992: José Remacle; Thierry Arnould; Carine Michiels
[The relation between venous stasis and the occurrence of pain].
Phlébologie 1992;45(1):33-7; discussion 38-9.
1991: O Toussaint; M Raes; José Remacle
Aging as a multi-step process characterized by a lowering of entropy production leading the cell to a sequence of defined stages.
Mechanisms of ageing and development 1991;61(1):45-64.
1991: José Remacle; A Houbion; Carine Michiels
[A comparison of various phlebotonic agents on human endothelial cells of veins subjected to hypoxia].
Phlébologie 1991;44(4):881-9.
1991: Carine Michiels; Thierry Arnould; A Houbion; José Remacle
[A comparative study of the protective effect of different phlebotonic agents on endothelial cells in hypoxia].
Phlébologie 1991;44(3):779-86.
1991: Carine Michiels; Thierry Arnould; A Houbion; José Remacle
[A comparative study of the protective effect of various phlebotonic agents on hypoxic endothelial cells].
Phlébologie 1991;44(2):509-16.
1991: E Pigeolet; José Remacle
Alteration of enzymes in ageing human fibroblasts in culture. V. Mechanisms of glutathione peroxidase modification.
Mechanisms of ageing and development 1991;58(1):93-109.
1991: C Michiels; José Remacle
Cytotoxicity of linoleic acid peroxide, malondialdehyde and 4-hydroxynonenal towards human fibroblasts.
Toxicology 1991;66(2):225-34.
1991: Carine Michiels; M Raes; A Houbion; José Remacle
Association of antioxidant systems in the protection of human fibroblasts against oxygen derived free radicals.
Free radical research communications 1991;14(5-6):323-34.
1991: E Pigeolet; José Remacle
Susceptibility of glutathione peroxidase to proteolysis after oxidative alteration by peroxides and hydroxyl radicals.
Free radical biology & medicine 1991;11(2):191-5.
1990: Carine Michiels; O Toussaint; José Remacle
Comparative study of oxygen toxicity in human fibroblasts and endothelial cells.
Journal of cellular physiology 1990;144(2):295-302.
1990: José Remacle; A Houbion; Isabelle Alexandre; Carine Michiels
[Behavior of human endothelial cells in hyperoxia and hypoxia: effect of Ginkor Fort].
Phlébologie 1990;43(2):375-86.
1990: E Pigeolet; Philippe Corbisier; A Houbion; D Lambert; Carine Michiels; M Raes; M D Zachary; José Remacle
Glutathione peroxidase, superoxide dismutase, and catalase inactivation by peroxides and oxygen derived free radicals.
Mechanisms of ageing and development 1990;51(3):283-97.
1990: Philippe Corbisier; M Raes; Carine Michiels; E Pigeolet; A Houbion; E Delaive; José Remacle
Respiratory activity of isolated rat liver mitochondria following in vitro exposure to oxygen species: a threshold study.
Mechanisms of ageing and development 1990;51(3):249-63.
1990: Philippe Corbisier; José Remacle
Involvement of mitochondria in cell degeneration.
European journal of cell biology 1990;51(1):173-82.
1990: Carine Michiels; M Raes; E Pigeolet; Philippe Corbisier; D Lambert; José Remacle
Importance of a threshold for error accumulation in cell degenerative processes. I. Modulation of the threshold in a model of free radical-induced cell degeneration.
Mechanisms of ageing and development 1990;51(1):41-54.
1989: E Remy; G Lenoir; A Houben; C Vandesteene; José Remacle
Inhibition of platelet-activating factor biosynthesis via the acetyltransferase by arachidonic and oleic acids in ionophore A23187-stimulated bovine neutrophils.
Biochimica et biophysica acta 1989;1005(1):87-92.
1989: V Bille; D Plainchamp; Solange Lavielle; Gérard Chassaing; José Remacle
Effect of the microenvironment on the kinetic properties of immobilized enzymes.
European journal of biochemistry / FEBS 1989;180(1):41-7.
1988: C Michiels; José Remacle
Quantitative study of natural antioxidant systems for cellular nitrofurantoin toxicity.
Biochimica et biophysica acta 1988;967(3):341-7.
1988: Carine Michiels; M Raes; M D Zachary; E Delaive; José Remacle
Microinjection of antibodies against superoxide dismutase and glutathione peroxidase.
Experimental cell research 1988;179(2):581-9.
1988: Carine Michiels; José Remacle
Use of the inhibition of enzymatic antioxidant systems in order to evaluate their physiological importance.
European journal of biochemistry / FEBS 1988;177(2):435-41.
1988: E Pigeolet; M Raes; A Houbion; José Remacle
Effect of procaine on cultivated human WI-38 fibroblasts.
Experimental gerontology 1988;23(2):87-96.
1987: V Bille; D Plainchamp; José Remacle
Affinity and stability modifications of immobilized alcohol dehydrogenase through multipoint copolymerization.
Biochimica et biophysica acta 1987;915(3):393-8.
1987: Philippe Corbisier; A Houbion; José Remacle
A new technique for highly sensitive detection of superoxide dismutase activity by chemiluminescence.
Analytical biochemistry 1987;164(1):240-7.
1986: V Bille; José Remacle
Simple-kinetic descriptions of alcohol dehydrogenase after immobilization on tresyl-chloride-activated agarose.
European journal of biochemistry / FEBS 1986;160(2):343-8.
1985: M Collot; M Kalff; E Delaive; José Remacle
Comparative study of conjugation between horseradish peroxidase and D-cytochrome b5. Incorporation into subcellular membranes.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1985;33(6):523-30.
1985: F Mbemba; A Houbion; M Raes; José Remacle
Subcellular localization and modification with ageing of glutathione, glutathione peroxidase and glutathione reductase activities in human fibroblasts.
Biochimica et biophysica acta 1985;838(2):211-20.
1985: M Somville; A Houben; M Raes; A Houbion; V Henin; José Remacle
Alteration of enzymes in ageing human fibroblasts in culture. III. Modification of superoxide dismutase as an environmental and reversible process.
Mechanisms of ageing and development 1985;29(1):35-51.
1984: A Houben; M Raes; A Houbion; José Remacle
Alteration of enzymes in ageing human fibroblasts in culture. II. Conditions for the reversibility and the mechanism of the alteration of glucose 6-phosphate dehydrogenase.
Mechanisms of ageing and development 1984;25(1-2):35-45.
1984: A Houben; M Raes; A Houbion; José Remacle
Alteration of enzymes in ageing human fibroblasts in culture. I. Conditions for the appearance of an alteration in glucose 6-phosphate dehydrogenase.
Mechanisms of ageing and development 1984;25(1-2):23-34.
1981: M Raes; A Houbion; José Remacle
The purification of plasma membranes from WI-38 fibroblasts: effects of ageing on their composition.
Biochimica et biophysica acta 1981;642(2):313-24.
1980: José Remacle; A Houbion; A Houben
Subcellular fractionation of WI-38 fibroblasts. Comparison between young and old cells.
Biochimica et biophysica acta 1980;630(1):57-70.
1980: A Houben; A Houbion; José Remacle
Short communication lysosomal and mitochondrial heat labile enzymes in Werner's syndrome fibroblasts.
Experimental gerontology 1980;15(6):629-31.