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Chengzhen Ren

Research Profile

Chemicals & Drugs

Disorders

Living Beings

Anatomy

Procedures

Physiology

Gene Expression Regulation, Neoplastic

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Publications

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Salahaldin A Tahir; Jianxiang Wang; Guang Yang; Wenjun Chang; Alexei Goltsov; Chengzhen Ren; Ki-Duk Song; Timothy C Thompson
Caveolin-1-LRP6 signaling module stimulates aerobic glycolysis in prostate cancer.
Guang Yang; Patricia Troncoso; Jorge Blando; Francesco J DeMayo; John DiGiovanni; Kohei Edamura; Alexei Goltsov; Shinji Kurosaka; Richard Logothetis; Chengzhen Ren; Timothy C Thompson
Caveolin-1 upregulation contributes to c-Myc-induced high-grade prostatic intraepithelial neoplasia and prostate cancer.
Guang Yang; Sanghee Park; Guangwen Cao; Alexei Goltsov; Chengzhen Ren; Luan D Truong; Francesco Demayo; Timothy C Thompson
MMTV promoter-regulated caveolin-1 overexpression yields defective parenchymal epithelia in multiple exocrine organs of transgenic mice.

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All Publications

2013: Salahaldin A Tahir; Jianxiang Wang; Guang Yang; Wenjun Chang; Alexei Goltsov; Chengzhen Ren; Ki-Duk Song; Timothy C Thompson
Caveolin-1-LRP6 signaling module stimulates aerobic glycolysis in prostate cancer.
Cancer research 2013;73(6):1900-11.
2012: Guang Yang; Patricia Troncoso; Jorge Blando; Francesco J DeMayo; John DiGiovanni; Kohei Edamura; Alexei Goltsov; Shinji Kurosaka; Richard Logothetis; Chengzhen Ren; Timothy C Thompson
Caveolin-1 upregulation contributes to c-Myc-induced high-grade prostatic intraepithelial neoplasia and prostate cancer.
Molecular cancer research : MCR 2012;10(2):218-29.
2010: Guang Yang; Sanghee Park; Guangwen Cao; Alexei Goltsov; Chengzhen Ren; Luan D Truong; Francesco Demayo; Timothy C Thompson
MMTV promoter-regulated caveolin-1 overexpression yields defective parenchymal epithelia in multiple exocrine organs of transgenic mice.
Experimental and molecular pathology 2010;89(1):9-19.
2008: Likun Li; ElMoataz Abdel Fattah; Guangwen Cao; Chengzhen Ren; Guang Yang; Alexei Goltsov; A Craig Chinault; Wei-Wen Cai; Terry L Timme; Timothy C Thompson
Glioma pathogenesis-related protein 1 exerts tumor suppressor activities through proapoptotic reactive oxygen species-c-Jun-NH2 kinase signaling.
Cancer research 2008;68(2):434-43.
2007: T Fujita; Terry L Timme; Ken-Ichi Tabata; Koji Naruishi; Nobuyuki Kusaka; M Watanabe; E Abdelfattah; J X Zhu; Chengzhen Ren; C Ren; Guang Yang; Alexei Goltsov; Hongyu Wang; Maria T Vlachaki; Bin S Teh; E. Brian Butler; Timothy C Thompson
Cooperative effects of adenoviral vector-mediated interleukin 12 gene therapy with radiotherapy in a preclinical model of metastatic prostate cancer.
Gene therapy 2007;14(3):227-36.
2006: Chengzhen Ren; Cheng-Hui Ren; Likun Li; Alexei Goltsov; Timothy C Thompson
Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene cluster.
Genomics 2006;88(2):163-72.
2004: Chengzhen Ren; Likun Li; Guang Yang; Terry L Timme; Alexei Goltsov; Chenghui Ren; Xiaorong Ji; Josephine Addai; Hongbin Luo; Michael Ittmann; Timothy C Thompson
RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer.
Cancer research 2004;64(3):969-76.
2003: Likun Li; Cheng Hui Ren; Salahaldin A Tahir; Chengzhen Ren; Timothy C Thompson
Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A.
Molecular and cellular biology 2003;23(24):9389-404.
2003: Salahaldin A Tahir; Chengzhen Ren; Terry L Timme; Yehoshua Gdor; Ron C Hoogeveen; Joel D Morrisett; Anna Frolov; Gustavo Ayala; Thomas M Wheeler; Timothy C Thompson
Development of an immunoassay for serum caveolin-1: a novel biomarker for prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 1):3653-9.
2003: Guangwen Cao; Guang Yang; Terry L Timme; Takashi Saika; Luan D Truong; Takefumi Satoh; Alexei Goltsov; Sang Hee Park; Taoyan Men; Nobuyuki Kusaka; Weihua Tian; Chengzhen Ren; Hongyu Wang; Dov Kadmon; Wei-Wen Cai; A Craig Chinault; Timothy B Boone; Allan Bradley; Timothy C Thompson
Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis.
The American journal of pathology 2003;162(4):1241-8.
2003: Takefumi Satoh; Terry L Timme; Takashi Saika; Shin Ebara; Guang Yang; Jianxiang Wang; Chengzhen Ren; Nobuyuki Kusaka; Vladimir Mouraviev; Timothy C Thompson
Adenoviral vector-mediated mRTVP-1 gene therapy for prostate cancer.
Human gene therapy 2003;14(2):91-101.
2002: Vladimir Mouraviev; Likun Li; Salahaldin A Tahir; Guang Yang; Terry M Timme; Alexei Goltsov; Chengzhen Ren; Takefumi Satoh; Thomas M Wheeler; Michael Ittmann; Brian J Miles; Robert J Amato; Dov Kadmon; Timothy C Thompson
The role of caveolin-1 in androgen insensitive prostate cancer.
The Journal of urology 2002;168(4 Pt 1):1589-96.
2002: Chengzhen Ren; Likun Li; Alexei Goltsov; Terry L Timme; Salahaldin A Tahir; Jianxiang Wang; Laura Garza; A Craig Chinault; Timothy C Thompson
mRTVP-1, a novel p53 target gene with proapoptotic activities.
Molecular and cellular biology 2002;22(10):3345-57.
2001: Christins K Pramudji; S Shimura; Shin Ebara; Guang Yang; Jianxiang Wang; Chengzhen Ren; Y Yuan; Salahaldin A Tahir; Terry L Timme; Timothy C Thompson
In situ prostate cancer gene therapy using a novel adenoviral vector regulated by the caveolin-1 promoter.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(12):4272-9.
2001: Brian J Miles; Moshe Shalev; Estuardo Aguilar-Cordova; Terry L Timme; H M Lee; Guang Yang; HL Adler; Kenneth Kernen; Christins K Pramudji; Takefumi Satoh; Yehoshua Gdor; Chengzhen Ren; Gustavo Ayala; Thomas M Wheeler; E. Brian Butler; Dov Kadmon; Timothy C Thompson
Prostate-specific antigen response and systemic T cell activation after in situ gene therapy in prostate cancer patients failing radiotherapy.
Human gene therapy 2001;12(16):1955-67.
2001: Likun Li; Guang Yang; Shin Ebara; Takefumi Satoh; Yasutomo Nasu; Terry L Timme; Chengzhen Ren; Jianxiang Wang; Salahaldin A Tahir; Timothy C Thompson
Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells.
Cancer research 2001;61(11):4386-92.
2000: Terry L Timme; Alexei Goltsov; Salahaldin A Tahir; Likun Li; Jianxiang Wang; Chengzhen Ren; Randal Johnston; Timothy C Thompson
Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis.
Oncogene 2000;19(29):3256-65.
1999: CH Bangma; Yasutomo Nasu; Chengzhen Ren; Timothy C Thompson
Metastasis-related genes in prostate cancer.
Seminars in oncology 1999;26(4):422-7.
1998: Yasutomo Nasu; Terry L Timme; Guang Yang; CH Bangma; Likun Li; Chengzhen Ren; Sang Hee Park; M DeLeon; Jianxiang Wang; Timothy C Thompson
Suppression of caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells.
Nature medicine 1998;4(9):1062-4.
1998: Guang Yang; Luan D Truong; Terry L Timme; Chengzhen Ren; Thomas M Wheeler; Sang Hee Park; Yasutomo Nasu; CH Bangma; Michael W Kattan; Peter T Scardino; Timothy C Thompson
Elevated expression of caveolin is associated with prostate and breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(8):1873-80.
1998: Chengzhen Ren; Guang Yang; Terry L Timme; Thomas M Wheeler; Timothy C Thompson
Reduced lysyl oxidase messenger RNA levels in experimental and human prostate cancer.
Cancer research 1998;58(6):1285-90.
1995: Timothy C Thompson; S H Park; Terry L Timme; Chengzhen Ren; James A Eastham; Lawrence A Donehower; Allan Bradley; Dov Kadmon; Guang Yang
Loss of p53 function leads to metastasis in ras+myc-initiated mouse prostate cancer.
Oncogene 1995;10(5):869-79.