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Jun Ren

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Maolong Dong; Rui Guo; Dahai Hu; Nan Hu; Yinan Hua; Shasha Jiang; Machender R Kandadi; Sreejayan Nair; Xihui Xu; Jun Ren
Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3β-dependent inhibition of apoptosis and ER stress.
Dongjuan Wang; Haichang Wang; Yabin Wang; Chao Zeng; Rongqing Zhang; Weijie Li; Peng Luo; Xiaowei Ma; Jun Ren; Tao Su; Dongdong Sun; Chen Wang; Feng Cao
Glucagon-Like Peptide-1 Protects Against Cardiac Microvascular Injury in Diabetes via a cAMP/PKA/Rho-Dependent Mechanism.
Bingfang Zhang; Yingmei Zhang; Karissa H La Cour; Kacy L Richmond; Xiao-Ming Wang; Jun Ren
Mitochondrial aldehyde dehydrogenase obliterates endoplasmic reticulum stress-induced cardiac contractile dysfunction via correction of autophagy.

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2013: Maolong Dong; Rui Guo; Dahai Hu; Nan Hu; Yinan Hua; Shasha Jiang; Machender R Kandadi; Sreejayan Nair; Xihui Xu; Jun Ren
Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3β-dependent inhibition of apoptosis and ER stress.
Biochimica et biophysica acta 2013;1832(6):848-63.
2013: Dongjuan Wang; Haichang Wang; Yabin Wang; Chao Zeng; Rongqing Zhang; Weijie Li; Peng Luo; Xiaowei Ma; Jun Ren; Tao Su; Dongdong Sun; Chen Wang; Feng Cao
Glucagon-Like Peptide-1 Protects Against Cardiac Microvascular Injury in Diabetes via a cAMP/PKA/Rho-Dependent Mechanism.
Diabetes 2013;62(5):1697-708.
2013: Bingfang Zhang; Yingmei Zhang; Karissa H La Cour; Kacy L Richmond; Xiao-Ming Wang; Jun Ren
Mitochondrial aldehyde dehydrogenase obliterates endoplasmic reticulum stress-induced cardiac contractile dysfunction via correction of autophagy.
Biochimica et biophysica acta 2013;1832(4):574-84.
2013: Xu Liang; Yuanli Lu; Herbert Kim Lyerly; Li Che; Lijun Di; Hanfang Jiang; Bin Shao; Xiaoli Wang; Zheng Wang; Ying Yan; Huabing Yang; Jing Yu; Jie Zhang; Xinna Zhou; Yulin Zhu; Jun Ren
Specific genetic polymorphisms of IL10-592 AA and IL10-819 TT genotypes lead to the key role for inducing docetaxel-induced liver injury in breast cancer patients.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2013;15(4):331-4.
2013: Nathan D Roe; Jun Ren
Oxidative activation of Ca(2+)/calmodulin-activated kinase II mediates ER stress-induced cardiac dysfunction and apoptosis.
American journal of physiology. Heart and circulatory physiology 2013;304(6):H828-39.
2013: Asli F Ceylan-Isik; Feng Dong; Maolong Dong; Sreejayan Nair; Subat Turdi; Masashi Yanagisawa; Yingmei Zhang; Jun Ren
Cardiomyocyte-specific deletion of endothelin receptor A rescues aging-associated cardiac hypertrophy and contractile dysfunction: role of autophagy.
Basic research in cardiology 2013;108(2):335.
2013: E Panzhinskiy; Jun Ren; B Culver; Y Hua; S Nair
Endoplasmic reticulum stress upregulates protein tyrosine phosphatase 1B and impairs glucose uptake in cultured myotubes.
Diabetologia 2013;56(3):598-607.
2013: Subat Turdi; Xiaoming Wang; Katherine M Bradley; Wei Ge; Nan Hu; Jun Ren
Interaction between maternal and postnatal high fat diet leads to a greater risk of myocardial dysfunction in offspring via enhanced lipotoxicity, IRS-1 serine phosphorylation and mitochondrial defects.
Journal of molecular and cellular cardiology 2013;55():117-29.
2013: Xihui Xu; Yingmei Zhang; Yinan Hua; Nair Sreejayan; Jun Ren
Akt2 knockout preserves cardiac function in high-fat diet-induced obesity by rescuing cardiac autophagosome maturation.
Journal of molecular cell biology 2013;5(1):61-3.
2013: Maolong Dong; Stephen P Ford; Peter W Nathanielsz; Qijun Zheng; Jun Ren
Maternal obesity, lipotoxicity and cardiovascular diseases in offspring.
Journal of molecular and cellular cardiology 2013;55():111-6.
2013: Subat Turdi; Nan Hu; Jun Ren
Tauroursodeoxycholic Acid mitigates high fat diet-induced cardiomyocyte contractile and intracellular ca(2+) anomalies.
PloS one 2013;8(5):e63615.
2013: Nan Hu; Erin K Lane; Feng Gao; Xuefeng Han; Yingmei Zhang; Jun Ren
Cardiac-specific overexpression of metallothionein rescues against cigarette smoking exposure-induced myocardial contractile and mitochondrial damage.
PloS one 2013;8(2):e57151.
2013: Xunliang Tong; Lemin Zheng; Jianying Hu; Liang Ji; Donghui Liu; Chenguang Niu; Bing Pan; Hui Peng; Jun Ren; Yining Huang
High-density lipoprotein of patients with Type 2 diabetes mellitus upregulates cyclooxgenase-2 expression and prostacyclin I-2 release in endothelial cells: relationship with HDL-associated sphingosine-1-phosphate.
Cardiovascular diabetology 2013;12(1):27.
2013: Shasha Jiang; Yingmei Zhang; Yunzeng Zou; Rui Guo; Jun Ren
Heavy metal scavenger metallothionein mitigates deep hypothermia-induced myocardial contractile anomalies: role of autophagy.
American journal of physiology. Endocrinology and metabolism 2013;304(1):E74-86.
2013: Rong-Huai Zhang; Glenda I Scott; Xiao-Ming Wang; Anna R Eason; Jian-Yuan Gao; Hai-Tao Guo; Jun Ren
Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis.
Biochimica et biophysica acta 2013;1832(1):128-41.
2013: Hongmei Sun; Xiaoli Wang; Guohong Song; Lijun Di; Jun Jia; Bo Ma; Jun Ren
CD44+/CD24- breast cancer cells isolated from MCF-7 cultures exhibit enhanced angiogenic properties.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2013;15(1):46-54.
2012: Li Che; Jun Jia; Yan-Hua Yuan; Jun Ren
Activation of sonic hedgehog signaling pathway is an independent potential prognosis predictor in human hepatocellular carcinoma patients.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2012;24(4):323-31.
2012: Xuefeng Han; Nan Hu; Subat Turdi; Yingmei Zhang; Rui Guo; Jun Ren
Influence of long-term caloric restriction on myocardial and cardiomyocyte contractile function and autophagy in mice.
The Journal of nutritional biochemistry 2012;23(12):1592-9.
2012: Jun Ren; Xiuqing Ding; Gregory D Funk; John J Greer
Anxiety-related mechanisms of respiratory dysfunction in a mouse model of Rett syndrome.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(48):17230-40.
2012: Linlin Li; Quan Li; Maolong Dong; Yinan Hua; Kyla R Jones; Derek T Smith; Ming Yuan; Jun Ren
Short-term lenalidomide (Revlimid) administration ameliorates cardiomyocyte contractile dysfunction in ob/ob obese mice.
Obesity (Silver Spring, Md.) 2012;20(11):2174-85.
2012: Bo Ma; Lijun Di; Jun Jia; Hanfang Jiang; Zhihao Lu; Guohong Song; Xiaoli Wang; Jing Yu; Xinna Zhou; Yulin Zhu; Jun Ren
Murine bone marrow stromal cells pulsed with homologous tumor-derived exosomes inhibit proliferation of liver cancer cells.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2012;14(10):764-73.
2012: Jun Ren; Xiuqing Ding; John J Greer
Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717.
Journal of applied physiology (Bethesda, Md. : 1985) 2012;113(7):1004-11.
2012: Machender R Kandadi; Arthur E Frankel; Jun Ren
Toll-like receptor 4 knockout protects against anthrax lethal toxin-induced cardiac contractile dysfunction: role of autophagy.
British journal of pharmacology 2012;167(3):612-26.
2012: Subat Turdi; Nathan D Roe; Feng Gao; Xuefeng Han; Nan Hu; Anna F Huff; Jun Ren
Cardiac-specific overexpression of catalase attenuates lipopolysaccharide-induced myocardial contractile dysfunction: role of autophagy.
Free radical biology & medicine 2012;53(6):1327-38.
2012: Lijun Di; Yan Han; Jun Jia; Bo Ma; Li Che; Gonghong Song; Fengling Wan; Xiaoli Wang; Huabing Yang; Miaoning You; Jing Yu; Yanhua Yuan; Chunrong Zhang; Jie Zhang; Xinna Zhou; Yulin Zhu; Jun Ren
Clinical safety of induced CTL infusion through recombinant adeno-associated virus-transfected dendritic cell vaccination in Chinese cancer patients.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2012;14(9):675-81.
2012: Baoshan Cao; Lijun Di; Jun Jia; H Kim Lyerly; Bo Ma; Liwen Ma; Guohong Song; Xiaoli Wang; Jing Yu; Yanhua Yuan; Xinna Zhou; Yulin Zhu; Jun Ren
Recombinant human endostatin could eliminate the pro-angiogenesis priority of SP cells sorted from non-small cell lung cancer cells.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2012;14(8):575-85.
2012: Lei Wang; Haijian Xing; Lifang Yang; Xiuling Yang; Shiqiang Yu; Sancheng Cao; Tao Chen; Dan Li; Jun Li; Yin Liu; Qiaomei Ma; Jun Ren; Danqiu Tian; Yi Wan; Jian Yang
Transcatheter closure of congenital perimembranous ventricular septal defect in children using symmetric occluders: an 8-year multiinstitutional experience.
The Annals of thoracic surgery 2012;94(2):592-8.
2012: Zheng Wang; Ying Yan; Huabing Yang; Jing Yu; Xiaohui Zheng; Xinna Zhou; Yulin Zhu; Lijun Di; Ningning Dong; Xu Liang; Jun Ren; Guohong Song; Xiaoli Wang; Herbert Kim Lyerly
Non-genetic risk factors and predicting efficacy for docetaxel--drug-induced liver injury among metastatic breast cancer patients.
Journal of gastroenterology and hepatology 2012;27(8):1348-52.
2012: Guohong Song; Alexander Stojadinovic; Wen Chen; Sidney W Fu; Jun Ren; Ziad Sahab; Yan-Gao Man
Conjunction of tumor cells with lymphocytes: implications for tumor invasion and metastasis.
Cancer epidemiology 2012;36(4):354-63.
2012: Yingmei Zhang; Kacy L Richmond; Feng Dong; Nan Hu; Yinan Hua; Jun Ren
Cardiac overexpression of metallothionein rescues cold exposure-induced myocardial contractile dysfunction through attenuation of cardiac fibrosis despite cardiomyocyte mechanical anomalies.
Free radical biology & medicine 2012;53(2):194-207.
2012: Ningning Dong; Jun Jia; Hanfang Jiang; Li Che; Lijun Di; Guohong Song; Chaoying Wang; Xiaoli Wang; Zheng Wang; Jing Yu; Xiaohui Zheng; Xinna Zhou; Budong Zhu; Jun Ren
Pharmacogenetic assessment of clinical outcome in patients with metastatic breast cancer treated with docetaxel plus capecitabine.
Journal of cancer research and clinical oncology 2012;138(7):1197-203.
2012: Xiao-Lin Lin; Yuan-Li Lu; Bo Ma; Tao Shen; Feng-Ling Wan; Xiao-Li Wang; Ying Yan; Yan-Hua Yuan; Li-Jun Di; Jun Jia; Xu Liang; Jun Ren
HER2-specific T lymphocytes kill both trastuzumab-resistant and trastuzumab-sensitive breast cell lines in vitro.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2012;24(2):143-50.
2012: Sreejayan Nair; Jun Ren
Autophagy and cardiovascular aging: lesson learned from rapamycin.
Cell cycle (Georgetown, Tex.) 2012;11(11):2092-9.
2012: Rui Guo; Jun Ren
Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation.
Cardiovascular research 2012;94(3):480-91.
2012: Hui Wang; Jun-Xing Zhao; Min Du; Nan Hu; Jun Ren; Mei-Jun Zhu
Side-stream smoking reduces intestinal inflammation and increases expression of tight junction proteins.
World journal of gastroenterology : WJG 2012;18(18):2180-7.
2012: Ying Yan; Guo-hong Song; Jian-ping Cheng; Li-jun Di; Jun Ren
[Detection and clinical value of epithelial cellular adhesion molecule (EpCAM) mRNA positive circulating tumor cells in metastatic breast cancer].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2012;44(2):275-80.
2012: Yingmei Zhang; Masashi Yanagisawa; Feng Dong; Yinan Hua; Linlin Li; Jennifer M Nunn; Jun Ren
Cardiac-specific knockout of ET(A) receptor mitigates low ambient temperature-induced cardiac hypertrophy and contractile dysfunction.
Journal of molecular cell biology 2012;4(2):97-107.
2012: Rui Guo; Nan Hu; Machender R Kandadi; Jun Ren
Facilitated ethanol metabolism promotes cardiomyocyte contractile dysfunction through autophagy in murine hearts.
Autophagy 2012;8(4):593-608.
2012: Yingmei Zhang; Ming Yuan; Piero Anversa; Katherine M Bradley; Feng Dong; Jun Ren
Insulin-like growth factor 1 alleviates high-fat diet-induced myocardial contractile dysfunction: role of insulin signaling and mitochondrial function.
Hypertension 2012;59(3):680-93.
2012: Aijun Sun; Jun Ren
Estrogen replacement therapy and cardiac function under metabolic syndrome: a treacherous art.
Hypertension 2012;59(3):552-4.
2012: Wei Ge; Jun Ren
mTOR-STAT3-notch signalling contributes to ALDH2-induced protection against cardiac contractile dysfunction and autophagy under alcoholism.
Journal of cellular and molecular medicine 2012;16(3):616-26.
2012: Yingmei Zhang; Jun Ren
Frontiers in research: obesity and health. Introduction.
Clinical and experimental pharmacology & physiology 2012;39(2):158-60.
2012: Xihui Xu; Jun Ren
Unmasking the janus faces of autophagy in obesity-associated insulin resistance and cardiac dysfunction.
Clinical and experimental pharmacology & physiology 2012;39(2):200-8.
2012: Subat Turdi; Zhenbiao Wu; Ming Yuan; Gail M Leedy; Jun Ren
Chronic social stress induces cardiomyocyte contractile dysfunction and intracellular Ca2+ derangement in rats.
Physiology & behavior 2012;105(2):498-509.
2012: Yi Quan; Jun Ren; Weikang Wang; Xiaoli Wang; Jingwen Wu; Ying Yan; Gen Yang; Qibin Fu; Yugang Wang
Impact of cell dissociation on identification of breast cancer stem cells.
Cancer biomarkers : section A of Disease markers 2012;12(3):125-33.
2012: Machender R Kandadi; Arthur E Frankel; Xuejun Yu; Jun Ren
Cardiac-specific catalase overexpression rescues anthrax lethal toxin-induced cardiac contractile dysfunction: role of oxidative stress and autophagy.
BMC medicine 2012;10():134.
2012: Yingmei Zhang; James R Sowers; Jun Ren
Pathophysiological insights into cardiovascular health in metabolic syndrome.
Experimental diabetes research 2012;2012():320534.
2012: Rong-Huai Zhang; Xiao-Ming Wang; Haitao Guo; Machender R Kandadi; Jun Ren
Ca+2/calmodulin-dependent protein kinase mediates glucose toxicity-induced cardiomyocyte contractile dysfunction.
Experimental diabetes research 2012;2012():829758.
2012: Yingmei Zhang; Haichang Wang; Sara A Babcock; Nan Hu; Jacalyn R Maris; Jun Ren
Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function.
BMC medicine 2012;10():40.
2012: Linlin Li; Yinan Hua; Jun Ren
Short-chain fatty acid propionate alleviates Akt2 knockout-induced myocardial contractile dysfunction.
Experimental diabetes research 2012;2012():851717.
2012: Gulinuer Awuti; Linlin Li; Halmurat Upur; Kurexi Younusi; Jun Ren
Epidemiological survey on the prevalence of periodontitis and diabetes mellitus in Uyghur adults from rural Hotan area in Xinjiang.
Experimental diabetes research 2012;2012():758921.
2011: Nathan D Roe; Jun Ren
Akt2 knockout mitigates chronic iNOS inhibition-induced cardiomyocyte atrophy and contractile dysfunction despite persistent insulin resistance.
Toxicology letters 2011;207(3):222-31.
2011: Jun Ren; Y Tang; S Tian; G Gu; W Jiao; D Li; W Li; H Liu; L Yan; Z Xu
Expression of CIP2A in renal cell carcinomas correlates with tumour invasion, metastasis and patients' survival.
British journal of cancer 2011;105(12):1905-11.
2011: Yu-Lin Zhu; Guo-Hong Song; Bin Wang; Rong Wu; Ai-Hua Zang; Xi Zhang; Xiao Zheng; Guo-Chun Cao; Ying Cheng; Xin Ding; Gang Feng; Zuo-Wei Hu; Jiang-Jin Huang; Shun-Chang Jiao; Wei-Lian Li; Jun Liang; Duan-Qi Liu; Kui-Feng Liu; Xue-Zhen Ma; Jun Ren
Multicenter clinical study for evaluation of efficacy and safety of transdermal fentanyl matrix patch in treatment of moderate to severe cancer pain in 474 chinese cancer patients.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2011;23(4):317-22.
2011: Ting Wang; Qing Yao; Jun Yi; Shi-Fang Yuan; Jun Yun; Ju-Liang Zhang; Jiang-Hao Chen; Zeng-Hui Han; Jun Ren; Ling Wang; Rui Ling
Application of colour Doppler in encircling constriction of the superficial femoral vein in primary deep venous insufficiency of the lower limbs.
Clinical and experimental pharmacology & physiology 2011;38(12):830-3.
2011: Yinan Hua; Jennifer M Nunn; Loren E Wold; Yingmei Zhang; Asli F Ceylan-Isik; Jun Ren
Chronic Akt activation accentuates aging-induced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy.
Basic research in cardiology 2011;106(6):1173-91.
2011: Wei Ge; Rui Guo; Jun Ren
AMP-dependent kinase and autophagic flux are involved in aldehyde dehydrogenase-2-induced protection against cardiac toxicity of ethanol.
Free radical biology & medicine 2011;51(9):1736-48.
2011: Yingmei Zhang; Zhi Xia; Karissa H La Cour; Jun Ren
Activation of Akt rescues endoplasmic reticulum stress-impaired murine cardiac contractile function via glycogen synthase kinase-3β-mediated suppression of mitochondrial permeation pore opening.
Antioxidants & redox signaling 2011;15(9):2407-24.
2011: Asli F Ceylan-Isik; Qun Li; Jun Ren
Insulin-like growth factor I (IGF-1) deficiency ameliorates sex difference in cardiac contractile function and intracellular Ca(2+) homeostasis.
Toxicology letters 2011;206(2):130-8.
2011: N D Roe; D P Thomas; Jun Ren
Inhibition of NADPH oxidase alleviates experimental diabetes-induced myocardial contractile dysfunction.
Diabetes, obesity & metabolism 2011;13(5):465-73.
2011: Xiao-li Wang; Bo Ma; Jun Jia; Yan-hua Yuan; Ying Yan; Li-jun Di; Guo-hong Song; Jing Yu; Jun Ren
[Dendritic cells infected by recombinant adeno-associated virus with CEA gene to induce antigen-specific CTL response to CD44(+)CD24(-/low) cells from MCF-7 breast cancer cell line].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2011;43(2):173-8.
2011: Mutallip Obulkasim; Ablikim Turdi; Nurmuhammat Amat; Muhtar Haxim; Rena Eziz; Hurxide Haji; Linlin Li; Xueyi Chen; Halmurat Upur; Jun Ren
Neuroendocrine-immune disorder in type 2 diabetic patients with retinopathy.
Clinical and experimental pharmacology & physiology 2011;38(4):229-32.
2011: Subat Turdi; Machender R Kandadi; Junxing Zhao; Anna F Huff; Min Du; Jun Ren
Deficiency in AMP-activated protein kinase exaggerates high fat diet-induced cardiac hypertrophy and contractile dysfunction.
Journal of molecular and cellular cardiology 2011;50(4):712-22.
2011: Heng Ma; Rui Guo; Lu Yu; Yingmei Zhang; Jun Ren
Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde.
European heart journal 2011;32(8):1025-38.
2011: Jing Yu; Jie Zhang; Yu-Lin Zhu; Li Che; Li-Jun Di; Jun Jia; Han-Fang Jiang; Xu Liang; Jun Ren; Guo-Hong Song; Chun-Rong Zhang
Mobilization of Peripheral Blood Stem Cells Using Regimen Combining Docetaxel with Granulocyte Colony-stimulating Factor in Breast Cancer Patients.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2011;23(1):49-53.
2011: Jing Yu; Li Che; Xu Liang; Jun Jia; Jie Zhang; Li jun DI; Han fang Jiang; Guo hong Song; Xiao li Wang; Hua bing Yang; Xin na Zhou; Yu lin Zhu; Jun Ren
[Randomized clinical case-control trial for the comparison of docetaxel plus thiotepa versus docetaxel plus capecitabine in patients with metastatic breast cancer].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2011;43(1):151-6.
2011: Xiu-Juan Fan; Hao Yu; Jun Ren
Homeostasis and compensatory homeostasis: bridging Western medicine and traditional chinese medicine.
Current cardiology reviews 2011;7(1):43-6.
2011: Gaspard Montandon; Wuxuan Qin; Hattie Liu; Jun Ren; John J Greer; Richard L Horner
PreBotzinger complex neurokinin-1 receptor-expressing neurons mediate opioid-induced respiratory depression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(4):1292-301.
2011: Han-Fang Jiang; Jian Fang; Jun Ren; Li-Jun DI; Gu-Hong Song; Li Che; Jing Yu; Yu-Ling Zhu
[Concurrent versus sequential systemic chemotherapy and whole brain radiation therapy for brain matastases in non-small-cell lung cancer patients].
Zhonghua zhong liu za zhi [Chinese journal of oncology] 2011;33(1):58-62.
2011: Zhihao Lu; Jun Jia; Lijun Di; Guohong Song; Yanhua Yuan; Bo Ma; Jing Yu; Yulin Zhu; Xiaoli Wang; Xinna Zhou; Jun Ren
DNA methyltransferase inhibitor CDA-2 synergizes with high-dose thiotepa and paclitaxel in killing breast cancer stem cells.
Frontiers in bioscience (Elite edition) 2011;3():240-9.
2011: Jian-Ping Cheng; Ying Yan; Xiang-Yi Wang; Yuan-Li Lu; Yan-Hua Yuan; Jun Jia; Jun Ren
MUC1-positive circulating tumor cells and MUC1 protein predict chemotherapeutic efficacy in the treatment of metastatic breast cancer.
Chinese journal of cancer 2011;30(1):54-61.
2011: Machender Reddy Kandadi; M K Unnikrishnan; Ajaya Kumar Sankara Warrier; Min Du; Jun Ren; Nair Sreejayan
Chromium (D-phenylalanine)3 alleviates high fat-induced insulin resistance and lipid abnormalities.
Journal of inorganic biochemistry 2011;105(1):58-62.
2011: Asli Ceylan Isik; Nair Sreejayan; Jun Ren
Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity-induced myocardial contractile dysfunction.
Journal of molecular and cellular cardiology 2011;50(1):107-16.
2011: Rui Si; Ling Tao; Hai F Zhang; Qiu J Yu; Rui Zhang; An L Lv; Ning Zhou; Feng Cao; Wen Y Guo; Jun Ren; Hai C Wang; Feng Gao
Survivin: a novel player in insulin cardioprotection against myocardial ischemia/reperfusion injury.
Journal of molecular and cellular cardiology 2011;50(1):16-24.
2011: Xiujuan Fan; Subat Turdi; Stephen P Ford; Yinan Hua; Mark Nijland; Meijun Zhu; Peter W Nathanielsz; Jun Ren
Influence of gestational overfeeding on cardiac morphometry and hypertrophic protein markers in fetal sheep.
The Journal of nutritional biochemistry 2011;22(1):30-7.
2010: Wei Ge; Yingmei Zhang; Xuefeng Han; We Ge; Jun Ren
Cardiac-specific overexpression of catalase attenuates paraquat-induced myocardial geometric and contractile alteration: role of ER stress.
Free radical biology & medicine 2010;49(12):2068-77.
2010: Yan Huang; Xu Yan; Jun X Zhao; Mei J Zhu; Richard J McCormick; Stephen P Ford; Peter W Nathanielsz; Jun Ren; Min Du
Maternal obesity induces fibrosis in fetal myocardium of sheep.
American journal of physiology. Endocrinology and metabolism 2010;299(6):E968-75.
2010: Bu-Dong Zhu; Xiao-Li Li; Yang Liu; Jing Chang; Yong Liu; Dong-Dong Zhang; Qiang Wang; Jun Ren; Chun-Ping Cui
Involvement of hepatopoietin Cn in the development of human hepatocellular carcinoma.
Clinical & experimental metastasis 2010;27(8):571-80.
2010: Yingmei Zhang; Jun Ren
Autophagy in ALDH2-elicited cardioprotection against ischemic heart disease: slayer or savior?
Autophagy 2010;6(8):1212-3.
2010: Bingfang Zhang; Subat Turdi; Quan Li; Faye L Lopez; Anna R Eason; Piero Anversa; Jun Ren
Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3beta, and PTEN.
Free radical biology & medicine 2010;49(7):1238-53.
2010: Jun Ren; Lakshmi Pulakat; Adam Whaley-Connell; James R Sowers
Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease.
Journal of molecular medicine (Berlin, Germany) 2010;88(10):993-1001.
2010: Lifeng Wang; Yicun Tao; Zijing Xie; Xinjian Ran; Minfang Zhang; Ye Wang; Xin Luo; Mengying Hu; Wenning Gen; Hamulati Wufuer; Linlin Li; Jun Ren; Xinming Mao
Prevalence of metabolic syndrome, insulin resistance, impaired fasting blood glucose, and dyslipidemia in Uygur and Kazak populations.
Journal of clinical hypertension (Greenwich, Conn.) 2010;12(9):741-5.
2010: Xuefeng Han; Jun Ren
Caloric restriction and heart function: is there a sensible link?
Acta pharmacologica Sinica 2010;31(9):1111-7.
2010: Subat Turdi; Xiujuan Fan; Ji Li; Junxing Zhao; Anna F Huff; Min Du; Jun Ren
AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction.
Aging cell 2010;9(4):592-606.
2010: Heng Ma; Lu Yu; Emily A Byra; Nan Hu; Kyoko Kitagawa; Keiichi I Nakayama; Toshihiro Kawamoto; Jun Ren
Aldehyde dehydrogenase 2 knockout accentuates ethanol-induced cardiac depression: role of protein phosphatases.
Journal of molecular and cellular cardiology 2010;49(2):322-9.
2010: Asli F Ceylan-Isik; Shawna M McBride; Jun Ren
Sex difference in alcoholism: who is at a greater risk for development of alcoholic complication?
Life sciences 2010;87(5-6):133-8.
2010: Qun Li; Subat Turdi; D Paul Thomas; Tianjie Zhou; Jun Ren
Intra-myocardial delivery of mesenchymal stem cells ameliorates left ventricular and cardiomyocyte contractile dysfunction following myocardial infarction.
Toxicology letters 2010;195(2-3):119-26.
2010: Rui Guo; Jun Ren
Alcohol and acetaldehyde in public health: from marvel to menace.
International journal of environmental research and public health 2010;7(4):1285-301.
2010: Guei-Jane Wang; Yun-Lian Lin; Chu-Huang Chen; Xi-Chen Wu; Jyh-Fei Liao; Jun Ren
Cellular calcium regulatory machinery of vasorelaxation elicited by petasin.
Clinical and experimental pharmacology & physiology 2010;37(3):309-15.
2010: Machender R Kandadi; Prabhakar K Rajanna; Mazhuvancherry K Unnikrishnan; Sai P Boddu; Yinan Hua; Ji Li; Min Du; Jun Ren; Nair Sreejayan
2-(3,4-Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a novel, synthetic small molecule that alleviates insulin resistance and lipid abnormalities.
Biochemical pharmacology 2010;79(4):623-31.
2010: Asli Ceylan Isik; Peng Zhao; Bingfang Zhang; Xiaoyan Xiao; Guohai Su; Jun Ren
Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis.
Journal of molecular and cellular cardiology 2010;48(2):367-78.
2010: Lian Zhang; Jun Ren; Kaifeng Pan; Junling Ma; Jiyou Li; Lin Shen; Xiaodong Zhang; Jie Li; Daiming Fan; Mitchell H Gail; Weicheng You
Detection of gastric carcinoma-associated MG7-Ag by serum immuno-PCR assay in a high-risk Chinese population, with implication for screening.
International journal of cancer. Journal international du cancer 2010;126(2):469-73.
2010: Jun Jia; Jun Ren; Jin Gu; Lijun Di; Guohong Song
Predominant sarcomatoid carcinoma of the lung concurrent with jejunal metastasis and leukocytosis.
Rare tumors 2010;2(3):e44.
2010: Jun Ren; Z C Pang; W G Gao; H R Nan; S J Wang; Lin Zhang; Q Qiao
C-reactive protein and gamma-glutamyltransferase concentrations in relation to the prevalence of type 2 diabetes diagnosed by glucose or HbA1c criteria in Chinese adults in Qingdao, China.
Experimental diabetes research 2010;2010():761715.
2010: Machender R Kandadi; Yinan Hua; Heng Ma; Qun Li; Shu-ru Kuo; Arthur E Frankel; Jun Ren
Anthrax lethal toxin suppresses murine cardiomyocyte contractile function and intracellular Ca2+ handling via a NADPH oxidase-dependent mechanism.
PloS one 2010;5(10):e13335.
2010: Rui Guo; Glenda I Scott; Jun Ren
Involvement of AMPK in alcohol dehydrogenase accentuated myocardial dysfunction following acute ethanol challenge in mice.
PloS one 2010;5(6):e11268.
2010: Rui Guo; Jun Ren
Alcohol dehydrogenase accentuates ethanol-induced myocardial dysfunction and mitochondrial damage in mice: role of mitochondrial death pathway.
PloS one 2010;5(1):e8757.
2010: Yinan Hua; Machender R Kandadi; Meijun Zhu; Jun Ren; Nair Sreejayan
Tauroursodeoxycholic acid attenuates lipid accumulation in endoplasmic reticulum-stressed macrophages.
Journal of cardiovascular pharmacology 2010;55(1):49-55.
2009: Rodney C Samaco; Caleigh Mandel-Brehm; Hsiao-Tuan Chao; Christopher S Ward; Sharyl L Fyffe-Maricich; Jun Ren; Keith Hyland; Christina Thaller; Stephen M Maricich; Peter Humphreys; John J Greer; Alan K Percy; Daniel G Glaze; Huda Y Zoghbi; Jeffrey L Neul
Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(51):21966-71.
2009: Heng Ma; Ji Li; Feng Gao; Jun Ren
Aldehyde dehydrogenase 2 ameliorates acute cardiac toxicity of ethanol: role of protein phosphatase and forkhead transcription factor.
Journal of the American College of Cardiology 2009;54(23):2187-96.
2009: Feng Dong; Yinan Hua; Peng Zhao; Jun Ren; Min Du; Nair Sreejayan
Chromium supplement inhibits skeletal muscle atrophy in hindlimb-suspended mice.
The Journal of nutritional biochemistry 2009;20(12):992-9.
2009: Qun Li; Ji Li; Jun Ren
UCF-101 mitigates streptozotocin-induced cardiomyocyte dysfunction: role of AMPK.
American journal of physiology. Endocrinology and metabolism 2009;297(4):E965-73.
2009: Jia Li; Feng Wu; Haifeng Zhang; Feng Fu; Lele Ji; Ling Dong; Qiuxia Li; Wenchong Liu; Yuan Zhang; Anlin Lv; Haichang Wang; Jun Ren; Feng Gao
Insulin inhibits leukocyte-endothelium adherence via an Akt-NO-dependent mechanism in myocardial ischemia/reperfusion.
Journal of molecular and cellular cardiology 2009;47(4):512-9.
2009: Subat Turdi; Robbie M Schamber; Nathan D Roe; Herbert G Chew; Bruce Culver; Jun Ren
Acute methamphetamine exposure inhibits cardiac contractile function.
Toxicology letters 2009;189(2):152-8.
2009: Qun Li; Lindsay K Hueckstaedt; Jun Ren
The protease inhibitor UCF-101 ameliorates streptozotocin-induced mouse cardiomyocyte contractile dysfunction in vitro: role of AMP-activated protein kinase.
Experimental physiology 2009;94(9):984-94.
2009: Yinan Hua; Heng Ma; Willis K Samson; Jun Ren
Neuronostatin inhibits cardiac contractile function via a protein kinase A- and JNK-dependent mechanism in murine hearts.
American journal of physiology. Regulatory, integrative and comparative physiology 2009;297(3):R682-9.
2009: Ming-Jia Yu; Jun Ren; Yong-Lun Zeng; Shi-Ning Zhou; Yong-Jun Lu
The Legionella pneumophila Dps homolog is regulated by iron and involved in multiple stress tolerance.
Journal of basic microbiology 2009;49 Suppl 1():S79-86.
2009: John J Greer; Jun Ren
Ampakine therapy to counter fentanyl-induced respiratory depression.
Respiratory physiology & neurobiology 2009;168(1-2):153-7.
2009: Heng Ma; Shi-Yan Li; Peisheng Xu; Sara A Babcock; E Kurt Dolence; Michael Brownlee; Ji Li; Jun Ren
Advanced glycation endproduct (AGE) accumulation and AGE receptor (RAGE) up-regulation contribute to the onset of diabetic cardiomyopathy.
Journal of cellular and molecular medicine 2009;13(8B):1751-64.
2009: Peng Zhao; Jingying Wang; Leilei He; Heng Ma; Xiaoyu Zhang; Xinglei Zhu; E Kurt Dolence; Jun Ren; Ji Li
Deficiency in TLR4 signal transduction ameliorates cardiac injury and cardiomyocyte contractile dysfunction during ischemia.
Journal of cellular and molecular medicine 2009;13(8A):1513-25.
2009: Xiao-Ping Yang; Zhao-Hui Pei; Jun Ren
Making up or breaking up: the tortuous role of platelet-derived growth factor in vascular ageing.
Clinical and experimental pharmacology & physiology 2009;36(8):739-47.
2009: Rui Guo; Heng Ma; Feng Gao; Li Zhong; Jun Ren
Metallothionein alleviates oxidative stress-induced endoplasmic reticulum stress and myocardial dysfunction.
Journal of molecular and cellular cardiology 2009;47(2):228-37.
2009: Shi-Yan Li; Sara A B Gilbert; Qun Li; Jun Ren
Aldehyde dehydrogenase-2 (ALDH2) ameliorates chronic alcohol ingestion-induced myocardial insulin resistance and endoplasmic reticulum stress.
Journal of molecular and cellular cardiology 2009;47(2):247-55.
2009: Z Qiao; Jun Ren; Huan Chen
Simvastatin reduces expression and activity of lipoprotein-associated phospholipase A(2) in the aorta of hypercholesterolaemic atherosclerotic rabbits.
The Journal of international medical research 2009;37(4):1029-37.
2009: Peng Zhao; Subat Turdi; Feng Dong; Xiaoyan Xiao; Guohai Su; Xinglei Zhu; Glenda I Scott; Jun Ren
Cardiac-specific overexpression of insulin-like growth factor I (IGF-1) rescues lipopolysaccharide-induced cardiac dysfunction and activation of stress signaling in murine cardiomyocytes.
Shock (Augusta, Ga.) 2009;32(1):100-7.
2009: Jun Ren; Sara A Babcock; Qun Li; Anna F Huff; Shi-Yan Li; Thomas A Doser
Aldehyde dehydrogenase-2 transgene ameliorates chronic alcohol ingestion-induced apoptosis in cerebral cortex.
Toxicology letters 2009;187(3):149-56.
2009: Jun Ren; Xiuqing Ding; Gregory D Funk; John J Greer
Ampakine CX717 protects against fentanyl-induced respiratory depression and lethal apnea in rats.
Anesthesiology 2009;110(6):1364-70.
2009: Asli F Ceylan-Isik; Kelly K Guo; Edward C Carlson; Jamie R Privratsky; Song-Jie Liao; Lu Cai; Alex F Chen; Jun Ren
Metallothionein abrogates GTP cyclohydrolase I inhibition-induced cardiac contractile and morphological defects: role of mitochondrial biogenesis.
Hypertension 2009;53(6):1023-31.
2009: Zhaohui Pei; Zhiqiang Zhuang; Pingxi Xiao; Jingzao Chen; Hanfei Sang; Jun Ren; Zhenbiao Wu; Guangmei Yan
Influence of infrasound exposure on the whole L-type calcium currents in rat ventricular myocytes.
Cardiovascular toxicology 2009;9(2):70-7.
2009: Jun Ren; Robert O Kelley
Cardiac health in women with metabolic syndrome: clinical aspects and pathophysiology.
Obesity (Silver Spring, Md.) 2009;17(6):1114-23.
2009: Rui Guo; Li Zhong; Jun Ren
Overexpression of aldehyde dehydrogenase-2 attenuates chronic alcohol exposure-induced apoptosis, change in Akt and Pim signalling in liver.
Clinical and experimental pharmacology & physiology 2009;36(5-6):463-8.
2009: Thomas A Doser; Subat Turdi; D Paul Thomas; Paul N Epstein; Shi-Yan Li; Jun Ren
Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction.
Circulation 2009;119(14):1941-9.
2009: Peng Zhao; Jingying Wang; Heng Ma; Yao Xiao; Leilei He; Chao Tong; Zhenhua Wang; Qiusheng Zheng; E Kurt Dolence; Sreejayan Nair; Jun Ren; Ji Li
A newly synthetic chromium complex-chromium (D-phenylalanine)3 activates AMP-activated protein kinase and stimulates glucose transport.
Biochemical pharmacology 2009;77(6):1002-10.
2009: Jianbo Sun; Zi-Liang Wang; Jin-Hong Duan; Jun Ren; Xian-Da Yang; Shun-Ling Dai; Ying Li
Targeted distribution of bacterial magnetosomes isolated from Magnetospirillum gryphiswaldense MSR-1 in healthy Sprague-Dawley rats.
Journal of nanoscience and nanotechnology 2009;9(3):1881-5.
2009: Feng Dong; Jun Ren
Adiponectin improves cardiomyocyte contractile function in db/db diabetic obese mice.
Obesity (Silver Spring, Md.) 2009;17(2):262-8.
2009: Jun Ren; Amy J Davidoff; Joanne S Ingwall
Creatine kinase inhibitor iodoacetamide antagonizes calcium-stimulated inotropy in cardiomyocytes.
Clinical and experimental pharmacology & physiology 2009;36(2):141-5.
2009: Subat Turdi; Rui Guo; Anna F Huff; Eliza M Wolf; Bruce Culver; Jun Ren
Cardiomyocyte contractile dysfunction in the APPswe/PS1dE9 mouse model of Alzheimer's disease.
PloS one 2009;4(6):e6033.
2009: Rama P Nair; Jun Ren
Pharmacotherapy of obesity - benefit, bias and hyperbole.
Current medicinal chemistry 2009;16(15):1888-97.
2009: Peng Zhao; Avadhesh C Sharma; Jun Ren
Pathogenesis and therapy of autoimmunity-induced dilated cardiomyopathy.
Frontiers in bioscience : a journal and virtual library 2009;14():1708-15.
2008: Jianbo Sun; Jin-Hong Duan; Shun-Ling Dai; Jun Ren; Lin Guo; Wei Jiang; Ying Li
Preparation and anti-tumor efficiency evaluation of doxorubicin-loaded bacterial magnetosomes: magnetic nanoparticles as drug carriers isolated from Magnetospirillum gryphiswaldense.
Biotechnology and bioengineering 2008;101(6):1313-20.
2008: Jun Ren; Loren E Wold
Mechanisms of alcoholic heart disease.
Therapeutic advances in cardiovascular disease 2008;2(6):497-506.
2008: Yicun Tao; Xinmin Mao; Zijing Xie; Xinjian Ran; Xiaoyan Liu; Ye Wang; Xin Luo; Mengying Hu; Wenning Gen; Minfang Zhang; Tao Wang; Jun Ren; Hamulati Wufuer; Linlin Li
The prevalence of type 2 diabetes and hypertension in Uygur and Kazak populations.
Cardiovascular toxicology 2008;8(4):155-9.
2008: Yizhen Liu; Julia Dolence; Jun Ren; Mna Rao; Nair Sreejayan
Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function.
Journal of cardiovascular pharmacology 2008;52(5):422-9.
2008: Asli Ceylan Isik; Rochelle M Fliethman; Loren E Wold; Jun Ren
Herbal and traditional Chinese medicine for the treatment of cardiovascular complications in diabetes mellitus.
Current diabetes reviews 2008;4(4):320-8.
2008: Jun Ren; Bang-Hao Zhu; David P Relling; Lucy B Esberg; Asli Ceylan Isik
High-fat diet-induced obesity leads to resistance to leptin-induced cardiomyocyte contractile response.
Obesity (Silver Spring, Md.) 2008;16(11):2417-23.
2008: Feng Dong; Machender Reddy Kandadi; Jun Ren; Nair Sreejayan
Chromium (D-phenylalanine)3 supplementation alters glucose disposal, insulin signaling, and glucose transporter-4 membrane translocation in insulin-resistant mice.
The Journal of nutrition 2008;138(10):1846-51.
2008: Peng Zhao; Xiaoyan Xiao; Agnes S Kim; M Fatima Leite; Jinxia Xu; Xinglei Zhu; Jun Ren; Li Ji
c-Jun inhibits thapsigargin-induced ER stress through up-regulation of DSCR1/Adapt78.
Experimental biology and medicine (Maywood, N.J.) 2008;233(10):1289-300.
2008: Nair Sreejayan; Xiaoping Yang; Kamalakannan Palanichamy; Kurt Dolence; Jun Ren
Antioxidant properties of argpyrimidine.
European journal of pharmacology 2008;593(1-3):30-5.
2008: Cindy X Fang; Feng Dong; D Paul Thomas; Heng Ma; Leilei He; Jun Ren
Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription.
American journal of physiology. Heart and circulatory physiology 2008;295(3):H1206-H1215.
2008: Qun Li; Asli Ceylan Isik; Li Ji; Jun Ren
Deficiency of insulin-like growth factor 1 reduces sensitivity to aging-associated cardiomyocyte dysfunction.
Rejuvenation research 2008;11(4):725-33.
2008: Haishan Xu; Jinhong Duan; Shunling Dai; Yunqing Wu; Renyu Sun; Jun Ren
alpha-Zearalanol attenuates oxLDL-induced ET-1 gene expression, ET-1 secretion and redox-sensitive intracellular signaling activation in human umbilical vein endothelial cells.
Toxicology letters 2008;179(3):163-8.
2008: Jun Ren; Jamie R Privratsky; Xiaoping Yang; Feng Dong; Edward C Carlson
Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts.
Critical care medicine 2008;36(7):2106-16.
2008: Jun Ren; Jun Jia; Hongmei Zhang; Liwang Zhang; Bo Ma; Hanfang Jiang; Lijun Di; Guohong Song; Jing Yu
Dendritic cells pulsed with alpha-fetoprotein and mutant P53 fused gene induce bi-targeted cytotoxic T lymphocyte response against hepatic carcinoma.
Cancer science 2008;99(7):1420-6.
2008: Rodney C Samaco; John D Fryer; Jun Ren; Sharyl Fyffe; Hsiao-Tuan Chao; Yaling Sun; John J Greer; Huda Y Zoghbi; Jeffrey L Neul
A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome.
Human molecular genetics 2008;17(12):1718-27.
2008: Rong Gao; Bang-hao Zhu; Shi-bo Tang; Jiang-feng Wang; Jun Ren
Scutellarein inhibits hypoxia- and moderately-high glucose-induced proliferation and VEGF expression in human retinal endothelial cells.
Acta pharmacologica Sinica 2008;29(6):707-12.
2008: Nair Sreejayan; Feng Dong; Machender R Kandadi; Xiaoping Yang; Jun Ren
Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice.
Obesity (Silver Spring, Md.) 2008;16(6):1331-7.
2008: Shi-Yan Li; Jun Ren
Cardiac overexpression of alcohol dehydrogenase exacerbates chronic ethanol ingestion-induced myocardial dysfunction and hypertrophy: role of insulin signaling and ER stress.
Journal of molecular and cellular cardiology 2008;44(6):992-1001.
2008: Feng Dong; Stephen P Ford; Mark Nijland; Peter W Nathanielsz; Jun Ren
Influence of maternal undernutrition and overfeeding on cardiac ciliary neurotrophic factor receptor and ventricular size in fetal sheep.
The Journal of nutritional biochemistry 2008;19(6):409-14.
2008: Subat Turdi; Peisheng Xu; Qun Li; Youqing Shen; Parhat Kerram; Jun Ren
Amidization of doxorubicin alleviates doxorubicin-induced contractile dysfunction and reduced survival in murine cardiomyocytes.
Toxicology letters 2008;178(3):197-201.
2008: Jia Li; Haifeng Zhang; Feng Wu; Ying Nan; Heng Ma; Wenyi Guo; Haichang Wang; Jun Ren; Undurti N Das; Feng Gao
Insulin inhibits tumor necrosis factor-alpha induction in myocardial ischemia/reperfusion: role of Akt and endothelial nitric oxide synthase phosphorylation.
Critical care medicine 2008;36(5):1551-8.
2008: Haishan Xu; Jinhong Duan; Wen Wang; Shunling Dai; Yunqing Wu; Renyu Sun; Jun Ren
Reactive oxygen species mediate oxidized low-density lipoprotein-induced endothelin-1 gene expression via extracellular signal-regulated kinase in vascular endothelial cells.
Journal of hypertension 2008;26(5):956-63.
2008: Li Ma; Banghao Zhu; Xiangping Chen; Jie Liu; Yongyuan Guan; Jun Ren
Abnormalities of sarcoplasmic reticulum Ca2+ mobilization in aortic smooth muscle cells from streptozotocin-induced diabetic rats.
Clinical and experimental pharmacology & physiology 2008;35(5-6):568-73.
2008: Jinhong Duan; Haishan Xu; Shunling Dai; Xiaoming Wang; Yunqing Wu; Yandong Zhang; Renyu Sun; Jun Ren
Phytoestrogen alpha-zearalanol inhibits homocysteine-induced endothelin-1 expression and oxidative stress in human umbilical vein endothelial cells.
Atherosclerosis 2008;197(2):549-55.
2008: Jun Ren; Jinhong Duan; D Paul Thomas; Xiaoping Yang; Nair Sreejayan; James R Sowers; Annarosa Leri; Jan Kajstura; Feng Gao; Piero Anversa
IGF-I alleviates diabetes-induced RhoA activation, eNOS uncoupling, and myocardial dysfunction.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;294(3):R793-802.
2008: Lin-Lin Li; Xiao-Li Ma; Jian-Xin Ran; Xiao-Feng Sun; Li-Ming Xu; Jun Ren; Xin-Min Mao
Genetic polymorphism of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala on ethnic susceptibility to diabetes in Uygur, Kazak and Han subjects.
Clinical and experimental pharmacology & physiology 2008;35(2):187-91.
2008: Lin-Lin Li; Xiao-Yan Liu; Jian-Xin Ran; Ye Wang; Xin Luo; Tao Wang; Jun Ren; Mayinuer Aisha; Rebiya Abudureheman; Adalaiti Xiawudong; Xiao-Chun Zhang; Xin-Min Mao
Analysis of prevalence and risk factors of hypertension among Uygur adults in Tushala and Hetian Xinjiang Uygur autonomous region.
Cardiovascular toxicology 2008;8(2):87-91.
2008: Peisheng Xu; Shi-Yan Li; Qun Li; Edward A Van Kirk; Jun Ren; William J Murdoch; Zhaojie Zhang; Maciej Radosz; Youqing Shen
Virion-mimicking nanocapsules from pH-controlled hierarchical self-assembly for gene delivery.
Angewandte Chemie (International ed. in English) 2008;47(7):1260-4.
2007: Xiaochun Zhang; Feng Dong; G E Mayer; D C Bruch; Jun Ren; Bruce Culver
Selective inhibition of cyclooxygenase-2 exacerbates methamphetamine-induced dopamine depletion in the striatum in rats.
Neuroscience 2007;150(4):950-8.
2007: Jianbo Sun; Jin-Hong Duan; Shun-Ling Dai; Jun Ren; Yan-Dong Zhang; Jie-Sheng Tian; Ying Li
In vitro and in vivo antitumor effects of doxorubicin loaded with bacterial magnetosomes (DBMs) on H22 cells: the magnetic bio-nanoparticles as drug carriers.
Cancer letters 2007;258(1):109-17.
2007: Jun Ren
Interaction between high-fat diet and alcohol dehydrogenase on ethanol-elicited cardiac depression in murine myocytes.
Obesity (Silver Spring, Md.) 2007;15(12):2932-41.
2007: Qun Li; Xiaoping Yang; Nair Sreejayan; Jun Ren
Insulin-like growth factor I deficiency prolongs survival and antagonizes paraquat-induced cardiomyocyte dysfunction: role of oxidative stress.
Rejuvenation research 2007;10(4):501-12.
2007: Qun Li; Jun Ren
Influence of cardiac-specific overexpression of insulin-like growth factor 1 on lifespan and aging-associated changes in cardiac intracellular Ca2+ homeostasis, protein damage and apoptotic protein expression.
Aging cell 2007;6(6):799-806.
2007: Lin-Lin Li; Xiao-Long Kang; Xin-Jian Ran; Ye Wang; Chang-Hui Wang; Lin Huang; Jun Ren; Xin Luo; Xin-Min Mao
Associations between 45T/G polymorphism of the adiponectin gene and plasma adiponectin levels with type 2 diabetes.
Clinical and experimental pharmacology & physiology 2007;34(12):1287-90.
2007: Feng Dong; Xiaoping Yang; Nair Sreejayan; Jun Ren
Chromium (D-phenylalanine)3 improves obesity-induced cardiac contractile defect in ob/ob mice.
Obesity (Silver Spring, Md.) 2007;15(11):2699-711.
2007: Feng Dong; Jun Ren
Fidarestat improves cardiomyocyte contractile function in db/db diabetic obese mice through a histone deacetylase Sir2-dependent mechanism.
Journal of hypertension 2007;25(10):2138-47.
2007: Qingwu W Shen; Mei J Zhu; Junfeng Tong; Jun Ren; Min Du
Ca2+/calmodulin-dependent protein kinase kinase is involved in AMP-activated protein kinase activation by alpha-lipoic acid in C2C12 myotubes.
American journal of physiology. Cell physiology 2007;293(4):C1395-403.
2007: Feng Dong; Qun Li; Nair Sreejayan; Jennifer M Nunn; Jun Ren
Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis.
Diabetes 2007;56(9):2201-12.
2007: Subat Turdi; Qun Li; Faye L Lopez; Jun Ren
Catalase alleviates cardiomyocyte dysfunction in diabetes: role of Akt, Forkhead transcriptional factor and silent information regulator 2.
Life sciences 2007;81(11):895-905.
2007: Feng Dong; Jun Ren
Fitness or fatness--the debate continues for the role of leptin in obesity-associated heart dysfunction.
Current diabetes reviews 2007;3(3):159-64.
2007: Quan-Jiang Zhang; Qiu-Xia Li; Hai-Feng Zhang; Kun-Ru Zhang; Wen-Yi Guo; Hai-Chang Wang; Zhuan Zhou; He-Ping Cheng; Jun Ren; Feng Gao
Swim training sensitizes myocardial response to insulin: role of Akt-dependent eNOS activation.
Cardiovascular research 2007;75(2):369-80.
2007: Jack T Saari; Loren E Wold; Jinhong Duan; Jun Ren; Hanqian L Carlson; Ann M Bode; Alex B Lentsch; Huawei Zeng; Dale A Schuschke
Cardiac nitric oxide synthases are elevated in dietary copper deficiency.
The Journal of nutritional biochemistry 2007;18(7):443-8.
2007: David P Relling; Lucy B Esberg; W Thomas Johnson; Eric Murphy; Edward Carlson; Henry C Lukaski; Jack T Saari; Jun Ren
Dietary interaction of high fat and marginal copper deficiency on cardiac contractile function.
Obesity (Silver Spring, Md.) 2007;15(5):1242-57.
2007: Jun Ren
Influence of gender on oxidative stress, lipid peroxidation, protein damage and apoptosis in hearts and brains from spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology 2007;34(5-6):432-8.
2007: Qun Li; Jun Ren
Chronic alcohol consumption alters mammalian target of rapamycin (mTOR), reduces ribosomal p70s6 kinase and p4E-BP1 levels in mouse cerebral cortex.
Experimental neurology 2007;204(2):840-4.
2007: Jun Ren; Qun Li; Shan Wu; Shi-Yan Li; Sara A Babcock
Cardiac overexpression of antioxidant catalase attenuates aging-induced cardiomyocyte relaxation dysfunction.
Mechanisms of ageing and development 2007;128(3):276-85.
2007: Qun Li; Shan Wu; Shi-Yan Li; Faye L Lopez; Min Du; Jan Kajstura; Piero Anversa; Jun Ren
Cardiac-specific overexpression of insulin-like growth factor 1 attenuates aging-associated cardiac diastolic contractile dysfunction and protein damage.
American journal of physiology. Heart and circulatory physiology 2007;292(3):H1398-403.
2007: Shi-Yan Li; Valerie K Sigmon; Sara A Babcock; Jun Ren
Advanced glycation endproduct induces ROS accumulation, apoptosis, MAP kinase activation and nuclear O-GlcNAcylation in human cardiac myocytes.
Life sciences 2007;80(11):1051-6.
2007: Mollie A Jay; Jun Ren
Peroxisome proliferator-activated receptor (PPAR) in metabolic syndrome and type 2 diabetes mellitus.
Current diabetes reviews 2007;3(1):33-9.
2007: Shi-Yan Li; Jun Ren
Assessment of protein glycoxidation in ventricular tissues.
Methods in molecular medicine 2007;139():313-28.
2007: Loren E Wold; Jun Ren
Mechanical measurement of contractile function of isolated ventricular myocytes.
Methods in molecular medicine 2007;139():263-70.
2007: Sanjoy Ghosh; Brian Rodrigues; Jun Ren
Rat models of cardiac insulin resistance.
Methods in molecular medicine 2007;139():113-43.
2007: Matthew S Stratton; Xiaoping Yang; Nair Sreejayan; Jun Ren
Impact of insulin-like growth factor-I on migration, proliferation and Akt-ERK signaling in early and late-passages of vascular smooth muscle cells.
Cardiovascular toxicology 2007;7(4):273-81.
2007: Jun Ren
Acetaldehyde and alcoholic cardiomyopathy: lessons from the ADH and ALDH2 transgenic models.
Novartis Foundation symposium 2007;285():69-76; discussion 76-9, 198-9.
2007: Shan Wu; Qun Li; Min Du; Shi-Yan Li; Jun Ren
Cardiac-specific overexpression of catalase prolongs lifespan and attenuates ageing-induced cardiomyocyte contractile dysfunction and protein damage.
Clinical and experimental pharmacology & physiology 2007;34(1-2):81-7.
2007: Cindy X Fang; Xiaoping Yang; Nair Sreejayan; Jun Ren
Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
Experimental neurology 2007;203(1):196-204.
2006: Qun Li; Cindy X Fang; Jennifer M Nunn; Jesse Zhang; Karissa H LaCour; Jun Ren
Characterization of cardiomyocyte excitation-contraction coupling in the FVB/N-C57BL/6 intercrossed "chocolate" brown mice.
Life sciences 2006;80(3):187-92.
2006: Peisheng Xu; Shi-Yan Li; Qun Li; Jun Ren; Edward A Van Kirk; William J Murdoch; Maciej Radosz; Youqing Shen
Biodegradable cationic polyester as an efficient carrier for gene delivery to neonatal cardiomyocytes.
Biotechnology and bioengineering 2006;95(5):893-903.
2006: Manuchair Ebadi; Holly M Brown-Borg; Jun Ren; Sushil Sharma; Shaik Shavali; Hesham El Refaey; Edward Carlson
Therapeutic efficacy of selegiline in neurodegenerative disorders and neurological diseases.
Current drug targets 2006;7(11):1513-29.
2006: Qun Li; Jun Ren
Cardiac overexpression of metallothionein rescues chronic alcohol intake-induced cardiomyocyte dysfunction: role of Akt, mammalian target of rapamycin and ribosomal p70s6 kinase.
Alcohol and alcoholism (Oxford, Oxfordshire) 2006;41(6):585-92.
2006: Xiaotian Zhang; Masakazu Yashiro; Masaichi Ohira; Jun Ren; Kosei Hirakawa
Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma.
Cancer science 2006;97(9):938-44.
2006: Feng Dong; Meghan M Taylor; Willis K Samson; Jun Ren
Intermedin (adrenomedullin-2) enhances cardiac contractile function via a protein kinase C- and protein kinase A-dependent pathway in murine ventricular myocytes.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;101(3):778-84.
2006: Cindy X Fang; Shan Wu; Jun Ren
Intracerebral hemorrhage elicits aberration in cardiomyocyte contractile function and intracellular Ca2+ transients.
Stroke; a journal of cerebral circulation 2006;37(7):1875-82.
2006: Xiaoping Yang; Shi-Yan Li; Feng Dong; Jun Ren; Nair Sreejayan
Insulin-sensitizing and cholesterol-lowering effects of chromium (D-Phenylalanine)3.
Journal of inorganic biochemistry 2006;100(7):1187-93.
2006: Shan Wu; Cindy X Fang; Jihye Kim; Jun Ren
Enhanced pulmonary inflammation following experimental intracerebral hemorrhage.
Experimental neurology 2006;200(1):245-9.
2006: Kelly K Guo; Jun Ren
Cardiac overexpression of alcohol dehydrogenase (ADH) alleviates aging-associated cardiomyocyte contractile dysfunction: role of intracellular Ca2+ cycling proteins.
Aging cell 2006;5(3):259-65.
2006: Jun Ren
Cardiac health and diabetes mellitus in women: problems and prospects.
Minerva cardioangiologica 2006;54(3):289-309.
2006: Shi-Yan Li; Xiaoping Yang; Asli Ceylan Isik; Min Du; Nair Sreejayan; Jun Ren
Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch.
Diabetologia 2006;49(6):1434-46.
2006: Feng Dong; Cindy X Fang; Xiaoping Yang; X Zhang; F L Lopez; Jun Ren
Cardiac overexpression of catalase rescues cardiac contractile dysfunction induced by insulin resistance: Role of oxidative stress, protein carbonyl formation and insulin sensitivity.
Diabetologia 2006;49(6):1421-33.
2006: Jun Ren; David P Relling
Leptin-induced suppression of cardiomyocyte contraction is amplified by ceramide.
Peptides 2006;27(6):1415-9.
2006: J Kim; Qun Li; Cindy X Fang; Jun Ren
Paradoxical effects of ginkgolide B on cardiomyocyte contractile function in normal and high-glucose environments.
Acta pharmacologica Sinica 2006;27(5):536-42.
2006: Xiaoping Yang; Thomas A Doser; Cindy X Fang; Jennifer M Nunn; Rajiv Janardhanan; Meijun Zhu; Nair Sreejayan; Mark T Quinn; Jun Ren
Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: role of oxidative stress.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):1024-6.
2006: Fangping Chen; Likun Gong; Ling Zhang; Hui Wang; Xinming Qi; Xiongfei Wu; Ying Xiao; Yan Cai; Linlin Liu; Xianghong Li; Jun Ren
Short courses of low dose dexamethasone delay bleomycin-induced lung fibrosis in rats.
European journal of pharmacology 2006;536(3):287-95.
2006: Asli Ceylan Isik; Karissa H LaCour; Jun Ren
Sex difference in cardiomyocyte function in normal and metallothionein transgenic mice: the effect of diabetes mellitus.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;100(5):1638-46.
2006: Loren E Wold; Asli Ceylan Isik; Cindy X Fang; Xiaoping Yang; Shi-Yan Li; Nair Sreejayan; Jamie R Privratsky; Jun Ren
Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme.
Free radical biology & medicine 2006;40(8):1419-29.
2006: Cindy X Fang; Thomas A Doser; Xiaoping Yang; Nair Sreejayan; Jun Ren
Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt.
Aging cell 2006;5(2):177-85.
2006: Ikuko Kato; Jun Ren; Lance K Heilbrun; Zora Djuric Longworth
Intra- and inter-individual variability in measurements of biomarkers for oxidative damage in vivo: Nutrition and Breast Health Study.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2006;11(2):143-52.
2006: Peisheng Xu; Edward A Van Kirk; Shiyan Li; William J Murdoch; Jun Ren; Muhammad Delwar Hussain; Maciej Radosz; Youqing Shen
Highly stable core-surface-crosslinked nanoparticles as cisplatin carriers for cancer chemotherapy.
Colloids and surfaces. B, Biointerfaces 2006;48(1):50-7.
2006: David P Relling; Lucy B Esberg; Cindy X Fang; W Thomas Johnson; Eric Murphy; Edward Carlson; Jack T Saari; Jun Ren
High-fat diet-induced juvenile obesity leads to cardiomyocyte dysfunction and upregulation of Foxo3a transcription factor independent of lipotoxicity and apoptosis.
Journal of hypertension 2006;24(3):549-61.
2006: Shan Wu; Jun Ren
Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-alpha.
Neuroscience letters 2006;394(2):158-62.
2006: Shi-Yan Li; Qun Li; James J Shen; Feng Dong; Valerie K Sigmon; Yizhen Liu; Jun Ren
Attenuation of acetaldehyde-induced cell injury by overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene in human cardiac myocytes: role of MAP kinase signaling.
Journal of molecular and cellular cardiology 2006;40(2):283-94.
2006: Feng Dong; Xiaochun Zhang; Jun Ren
Leptin regulates cardiomyocyte contractile function through endothelin-1 receptor-NADPH oxidase pathway.
Hypertension 2006;47(2):222-9.
2006: Qun Li; Jun Ren
Cardiac overexpression of metallothionein attenuates chronic alcohol intake-induced cardiomyocyte contractile dysfunction.
Cardiovascular toxicology 2006;6(3-4):173-82.
2006: Jinhong Duan; Shunling Dai; Cindy X Fang; Renyu Sun; Shaik Shavali; Sushil K Sharma; Manuchair Ebadi; Jun Ren
Phytoestrogen alpha-zearalanol antagonizes homocysteine-induced imbalance of nitric oxide/endothelin-1 and apoptosis in human umbilical vein endothelial cells.
Cell biochemistry and biophysics 2006;45(2):137-45.
2006: Asli Ceylan Isik; Karissa H LaCour; Jun Ren
Gender disparity of streptozotocin-induced intrinsic contractile dysfunction in murine ventricular myocytes: role of chronic activation of Akt.
Clinical and experimental pharmacology & physiology 2006;33(1-2):102-8.
2006: Feng Dong; Xiaochun Zhang; Xiaoping Yang; Lucy B Esberg; H Yang; Zhaojie Zhang; Bruce Culver; Jun Ren
Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice.
The Journal of endocrinology 2006;188(1):25-36.
2006: Xiaoping Yang; D Paul Thomas; Xiaochun Zhang; Bruce W Culver; Brenda M Alexander; William J Murdoch; Mysore N A Rao; David A Tulis; Jun Ren; Nair Sreejayan
Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):85-90.
2006: Asli Ceylan Isik; Shan Wu; Qun Li; Shi-Yan Li; Jun Ren
High-dose benfotiamine rescues cardiomyocyte contractile dysfunction in streptozotocin-induced diabetes mellitus.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;100(1):150-6.
2006: Jun Ren; Shan Wu
A burning issue: do sepsis and systemic inflammatory response syndrome (SIRS) directly contribute to cardiac dysfunction?
Frontiers in bioscience : a journal and virtual library 2006;11():15-22.
2005: Jun Ren; David P Relling
Interaction between tumor necrosis factor-alpha and leptin-induced inhibition of cardiac contractile function in isolated ventricular myocytes.
Cytokine 2005;32(5):213-8.
2005: Muralikrishnan Dhanasekaran; Jun Ren
The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus.
Current neurovascular research 2005;2(5):447-59.
2005: Xiaochun Zhang; Feng Dong; Qun Li; Anthony J Borgerding; Aaron L Klein; Jun Ren
Cardiac overexpression of catalase antagonizes ADH-associated contractile depression and stress signaling after acute ethanol exposure in murine myocytes.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(6):2246-54.
2005: Shawna M McBride; Francis W Flynn; Jun Ren
Cardiovascular alteration and treatment of hypertension: do men and women differ?
Endocrine 2005;28(2):199-207.
2005: Cindy X Fang; Feng Dong; Bonnie H Ren; Paul N Epstein; Jun Ren
Metallothionein alleviates cardiac contractile dysfunction induced by insulin resistance: role of Akt phosphorylation, PTB1B, PPARgamma and c-Jun.
Diabetologia 2005;48(11):2412-21.
2005: Xiaoping Yang; Mei J Zhu; Nair Sreejayan; Jun Ren; Min Du
Angiotensin II promotes smooth muscle cell proliferation and migration through release of heparin-binding epidermal growth factor and activation of EGF-receptor pathway.
Molecules and cells 2005;20(2):263-70.
2005: Shi-Yan Li; Cindy X Fang; Nicholas S Aberle; Bonnie H Ren; Asli Ceylan Isik; Jun Ren
Inhibition of PI-3 kinase/Akt/mTOR, but not calcineurin signaling, reverses insulin-like growth factor I-induced protection against glucose toxicity in cardiomyocyte contractile function.
The Journal of endocrinology 2005;186(3):491-503.
2005: Feng Dong; Xiaochun Zhang; Bruce Culver; Herbert G Chew; Robert O Kelley; Jun Ren
Dietary iron deficiency induces ventricular dilation, mitochondrial ultrastructural aberrations and cytochrome c release: involvement of nitric oxide synthase and protein tyrosine nitration.
Clinical science (London, England : 1979) 2005;109(3):277-86.
2005: Feng Dong; Stephen P Ford; Cindy X Fang; Mark Nijland; Peter W Nathanielsz; Jun Ren
Maternal nutrient restriction during early to mid gestation up-regulates cardiac insulin-like growth factor (IGF) receptors associated with enlarged ventricular size in fetal sheep.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2005;15(4):291-9.
2005: Loren E Wold; Asli Ceylan Isik; Jun Ren
Oxidative stress and stress signaling: menace of diabetic cardiomyopathy.
Acta pharmacologica Sinica 2005;26(8):908-17.
2005: Loren E Wold; Kaushik Dutta; Meredith M Mason; Jun Ren; Steven E Cala; Mary L Schwanke; Amy J Davidoff
Impaired SERCA function contributes to cardiomyocyte dysfunction in insulin resistant rats.
Journal of molecular and cellular cardiology 2005;39(2):297-307.
2005: Shi-Yan Li; Y Liu; Valerie K Sigmon; A McCort; Jun Ren
High-fat diet enhances visceral advanced glycation end products, nuclear O-Glc-Nac modification, p38 mitogen-activated protein kinase activation and apoptosis.
Diabetes, obesity & metabolism 2005;7(4):448-54.
2005: Feng Dong; Lucy B Esberg; Zamzam K Roughead; Jun Ren; Jack T Saari
Increased contractility of cardiomyocytes from copper-deficient rats is associated with upregulation of cardiac IGF-I receptor.
American journal of physiology. Heart and circulatory physiology 2005;289(1):H78-84.
2005: Akanksha Gupta; Nicholas S Aberle; Ruchita Kapoor; Jun Ren; Avadhesh C Sharma
Bigendothelin-1 via p38-MAPK-dependent mechanism regulates adult rat ventricular myocyte contractility in sepsis.
Biochimica et biophysica acta 2005;1741(1-2):127-39.
2005: Jun Ren
Lessons from the leptin paradox in cardiac regulation--too much versus too little.
The Journal of physiology 2005;565(Pt 2):347.
2005: Feng Dong; Xiaochun Zhang; Loren E Wold; Qun Ren; Zhaojie Zhang; Jun Ren
Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: role of ETB receptor, NADPH oxidase and caveolin-1.
British journal of pharmacology 2005;145(3):323-33.
2005: Shi-Yan Li; Min Du; E Kurt Dolence; Cindy X Fang; Gabriele E Mayer; Asli Ceylan Isik; Karissa H LaCour; Xiaoping Yang; Christopher J Wilbert; Nair Sreejayan; Jun Ren
Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification.
Aging cell 2005;4(2):57-64.
2005: Xiaoping Yang; Nair Sreejayan; Jun Ren
Views from within and beyond: narratives of cardiac contractile dysfunction under senescence.
Endocrine 2005;26(2):127-37.
2005: Akanksha Gupta; Nicholas S Aberle; Jun Ren; Avadhesh C Sharma
Endothelin-converting enzyme-1-mediated signaling in adult rat ventricular myocyte contractility and apoptosis during sepsis.
Journal of molecular and cellular cardiology 2005;38(3):527-37.
2005: Jun Ren; Cindy X Fang
Small guanine nucleotide-binding protein Rho and myocardial function.
Acta pharmacologica Sinica 2005;26(3):279-85.
2005: Xiaoping Yang; Kamalakannan Palanichamy; Allyn C Ontko; M N A Rao; Cindy X Fang; Jun Ren; Nair Sreejayan
A newly synthetic chromium complex--chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance.
FEBS letters 2005;579(6):1458-64.
2005: Xiaochun Zhang; Feng Dong; Jun Ren; Meghan J Driscoll; Bruce Culver
High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex.
Experimental neurology 2005;191(2):318-25.
2005: Loren E Wold; Nicholas S Aberle; Jun Ren
Doxorubicin induces cardiomyocyte dysfunction via a p38 MAP kinase-dependent oxidative stress mechanism.
Cancer detection and prevention 2005;29(3):294-9.
2005: Feng Dong; Xiaochun Zhang; Shi-Yan Li; Zhaojie Zhang; Qun Ren; Bruce Culver; Jun Ren
Possible involvement of NADPH oxidase and JNK in homocysteine-induced oxidative stress and apoptosis in human umbilical vein endothelial cells.
Cardiovascular toxicology 2005;5(1):9-20.
2005: Shi-Yan Li; Kish L Golden; Yang Jiang; Guei-Jane Wang; Jamie R Privratsky; Xiaochun Zhang; Anna R Eason; Bruce Culver; Jun Ren
Inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase differentially regulates contractile function in cardiac myocytes from normotensive and spontaneously hypertensive rats: role of Ca2+ regulatory proteins.
Cell biochemistry and biophysics 2005;42(1):1-12.
2004: Hai-Shan Xu; Jinhong Duan; Shunling Dai; Yunqing Wu; Renyu Sun; Jun Ren
Phytoestrogen alpha-zearalanol antagonizes oxidized LDL-induced inhibition of nitric oxide production and stimulation of endothelin-1 release in human umbilical vein endothelial cells.
Endocrine 2004;25(3):235-45.
2004: Shunling Dai; Jinhong Duan; Yuan Lu; Yihua Zhang; Jinxuan Cheng; Jun Ren; Xiaoyuan Zhao; Yunqing Wu; Yue Yu; Ping-ping Zuo; Yiyong Wu; Qinsheng Ge
Phytoestrogen alpha-zearalanol inhibits atherogenesis and improves lipid profile in ovariectomized cholesterol-fed rabbits.
Endocrine 2004;25(2):121-9.
2004: Shunling Dai; Jinhong Duan; Yuan Lu; Jinxuan Cheng; Jun Ren; Wenhui Deng; Yiyong Wu
Alpha-Zearalanol, a phytoestrogen for cardiovascular therapy.
Endocrine 2004;25(2):117-9.
2004: Jun Ren; Asli Ceylan Isik
Diabetic cardiomyopathy: do women differ from men?
Endocrine 2004;25(2):73-83.
2004: Peisheng Xu; Huadong Tang; Shiyan Li; Jun Ren; Edward A Van Kirk; William J Murdoch; Maciej Radosz; Youqing Shen
Enhanced stability of core-surface cross-linked micelles fabricated from amphiphilic brush copolymers.
Biomacromolecules 2004;5(5):1736-44.
2004: Nicholas S Aberle; Larry Burd; Bonnie H Zhao; Jun Ren
Acetaldehyde-induced cardiac contractile dysfunction may be alleviated by vitamin B1 but not by vitamins B6 or B12.
Alcohol and alcoholism (Oxford, Oxfordshire) 2004;39(5):450-4.
2004: AJ Davidoff; Michael B Davidson; Marybeth W Carmody; Mari-Elena Davis; Jun Ren
Diabetic cardiomyocyte dysfunction and myocyte insulin resistance: role of glucose-induced PKC activity.
Molecular and cellular biochemistry 2004;262(1-2):155-63.
2004: Loren E Wold; Jun Ren
Streptozotocin directly impairs cardiac contractile function in isolated ventricular myocytes via a p38 map kinase-dependent oxidative stress mechanism.
Biochemical and biophysical research communications 2004;318(4):1066-71.
2004: Lucy B Esberg; Xiaochun Zhang; Glenda I Scott; Bruce Culver; Jun Ren
Impact of gender on basal and insulin-like growth factor I-regulated nitric oxide synthase activity in adult rat left ventricular myocytes.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2004;138(2):141-6.
2004: Nicholas S Aberle; Kap J Lee; Jun Ren
Korean anti-inflammatory compound allergina enhances cardiac contractile function in isolated ventricular cardiomyocytes.
Journal of alternative and complementary medicine (New York, N.Y.) 2004;10(3):514-8.
2004: Jinhong Duan; Lucy B Esberg; Shunling Dai; Nicholas S Aberle; Faye L Lopez; Jun Ren
Comparison of cardiac contractile and intracellular Ca2+ response between estrogen and phytoestrogen alpha-zearalanol in ventricular myocytes.
Endocrine 2004;24(1):33-8.
2004: Kadon K Hintz; Jun Ren
Phytoestrogenic isoflavones daidzein and genistein reduce glucose-toxicity-induced cardiac contractile dysfunction in ventricular myocytes.
Endocrine research 2004;30(2):215-23.
2004: AJ Davidoff; Meredith M Mason; Michael B Davidson; Marybeth W Carmody; Kadon K Hintz; Loren E Wold; Deborah A Podolin; Jun Ren
Sucrose-induced cardiomyocyte dysfunction is both preventable and reversible with clinically relevant treatments.
American journal of physiology. Endocrinology and metabolism 2004;286(5):E718-24.
2004: Xiaochun Zhang; Shi-Yan Li; RA Brown; Jun Ren
Ethanol and acetaldehyde in alcoholic cardiomyopathy: from bad to ugly en route to oxidative stress.
Alcohol (Fayetteville, N.Y.) 2004;32(3):175-86.
2004: Jun Ren
Leptin and hyperleptinemia - from friend to foe for cardiovascular function.
The Journal of endocrinology 2004;181(1):1-10.
2004: Shi-Yan Li; Mark Gomelsky; Jinhong Duan; Zhaojie Zhang; Larissa Gomelsky; Xiaochun Zhang; Paul N Epstein; Jun Ren
Overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene prevents acetaldehyde-induced cell injury in human umbilical vein endothelial cells: role of ERK and p38 mitogen-activated protein kinase.
The Journal of biological chemistry 2004;279(12):11244-52.
2004: Guei-Jane Wang; Jyh-Fei Liao; Kadon K Hintz; Wen-Pin Chen; Ming-Jai Su; Yun-Lian Lin; Chuen-Chao Shi; Chieh-Fu Chen; Jun Ren
Calcium-antagonizing activity of S-petasin, a hypotensive sesquiterpene from Petasites formosanus, on inotropic and chronotropic responses in isolated rat atria and cardiac myocytes.
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(3):322-9.
2004: Jun Ren; Xiaochun Zhang; Glenda I Scott; Lucy B Esberg; Bonnie H Ren; Bruce Culver; Alex F Chen
Adenovirus gene transfer of recombinant endothelial nitric oxide synthase enhances contractile function in ventricular myocytes.
Journal of cardiovascular pharmacology 2004;43(2):171-7.
2004: Aaron L Klein; Loren E Wold; Jun Ren
The cyclooxygenase-2 product prostaglandin E2 modulates cardiac contractile function in adult rat ventricular cardiomyocytes.
Pharmacological research : the official journal of the Italian Pharmacological Society 2004;49(2):99-103.
2004: Lucy B Esberg; Jun Ren
The oxygen radical generator pyrogallol impairs cardiomyocyte contractile function via a superoxide and p38 MAP kinase-dependent pathway: protection by anisodamine and tetramethylpyrazine.
Cardiovascular toxicology 2004;4(4):375-84.
2004: Nicholas S Aberle; Matthew J Picklo; Venkataraman Amarnath; Jun Ren
Inhibition of cardiac myocyte contraction by 4-hydroxy-trans-2-nonenal.
Cardiovascular toxicology 2004;4(1):21-8.
2004: Faye L Norby; Nicholas S Aberle; J Kajstura; P Anversa; Jun Ren
Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and beta-adrenergic response in ventricular myocytes.
The Journal of endocrinology 2004;180(1):175-82.
2004: Jun Ren; James E Porter; Loren E Wold; Nicholas S Aberle; Dhanasekaran Muralikrishnan; James R Haselton
Depressed contractile function and adrenergic responsiveness of cardiac myocytes in an experimental model of Parkinson disease, the MPTP-treated mouse.
Neurobiology of aging 2004;25(1):131-8.
2003: David P Relling; Kadon K Hintz; Jun Ren
Acute exposure of ceramide enhances cardiac contractile function in isolated ventricular myocytes.
British journal of pharmacology 2003;140(7):1163-8.
2003: Kadon K Hintz; Jun Ren
Tetramethylpyrazine elicits disparate responses in cardiac contraction and intracellular Ca(2+) transients in isolated adult rat ventricular myocytes.
Vascular pharmacology 2003;40(4):213-7.
2003: Xiaochun Zhang; Yunyi Wen; Xiaorong Xu; Feng Dong; Jun Ren
Agonist-stimulated Ca(2+) transport in mesenteric vascular smooth muscle cells of vitamin D(3)-induced calcium overload rats.
Vascular pharmacology 2003;40(4):189-95.
2003: Nicholas S Aberle; Jamie R Privratsky; Larry Burd; Jun Ren
Combined acetaldehyde and nicotine exposure depresses cardiac contraction in ventricular myocytes: prevention by folic acid.
Neurotoxicology and teratology 2003;25(6):731-6.
2003: Kadon K Hintz; Nicholas S Aberle; Jun Ren
Insulin resistance induces hyperleptinemia, cardiac contractile dysfunction but not cardiac leptin resistance in ventricular myocytes.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2003;27(10):1196-203.
2003: Feng Dong; Jun Ren
Insulin-like growth factors (IGFs) and IGF-binding proteins in nephrotic syndrome children on glucocorticoid.
Pharmacological research : the official journal of the Italian Pharmacological Society 2003;48(4):319-23.
2003: Lucy B Esberg; Jun Ren
Role of nitric oxide, tetrahydrobiopterin and peroxynitrite in glucose toxicity-associated contractile dysfunction in ventricular myocytes.
Diabetologia 2003;46(10):1419-27.
2003: David V Folden; Akanksha Gupta; Avadhesh C Sharma; Shi-Yan Li; Jack T Saari; Jun Ren
Malondialdehyde inhibits cardiac contractile function in ventricular myocytes via a p38 mitogen-activated protein kinase-dependent mechanism.
British journal of pharmacology 2003;139(7):1310-6.
2003: Jamie R Privratsky; Loren E Wold; James R Sowers; Mark T Quinn; Jun Ren
AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase.
Hypertension 2003;42(2):206-12.
2003: Shiyan Li; Bruce Culver; Jun Ren
Benefit and risk of exercise on myocardial function in diabetes.
Pharmacological research : the official journal of the Italian Pharmacological Society 2003;48(2):127-32.
2003: Kadon K Hintz; David P Relling; Jack T Saari; Anthony J Borgerding; Jinhong Duan; Bonnie H Ren; Kosai Kato; Paul N Epstein; Jun Ren
Cardiac overexpression of alcohol dehydrogenase exacerbates cardiac contractile dysfunction, lipid peroxidation, and protein damage after chronic ethanol ingestion.
Alcoholism, clinical and experimental research 2003;27(7):1090-8.
2003: Jun Ren
Paradoxical effects of pyruvate on cardiac contractile function under normal and high glucose in ventricular myocytes.
Pharmacological research : the official journal of the Italian Pharmacological Society 2003;48(1):25-9.
2003: Loren E Wold; Dhanasekaran Muralikrishnan; CB Albano; Faye L Norby; Manuchair Ebadi; Jun Ren
Insulin-like growth factor I (IGF-1) supplementation prevents diabetes-induced alterations in coenzymes Q9 and Q10.
Acta diabetologica 2003;40(2):85-90.
2003: Xiaochun Zhang; Aaron L Klein; Nicholas S Alberle; Faye L Norby; Bonnie H Ren; Jinhong Duan; Jun Ren
Cardiac-specific overexpression of catalase rescues ventricular myocytes from ethanol-induced cardiac contractile defect.
Journal of molecular and cellular cardiology 2003;35(6):645-52.
2003: Jun Ren; Yunyi Wen; Kadon K Hintz
Influence of hypertension on cardiac contractile response of human erythrocyte-derived depressing factor in ventricular myocytes.
Journal of hypertension 2003;21(6):1183-90.
2003: Gerard T Berry; Shuang Wu; Roberto Buccafusca; Jun Ren; Linda W Gonzales; Philip L Ballard; Jeffrey A Golden; Martin J Stevens; John J Greer
Loss of murine Na+/myo-inositol cotransporter leads to brain myo-inositol depletion and central apnea.
The Journal of biological chemistry 2003;278(20):18297-302.
2003: Xiaochun Zhang; Gang Ye; Jinhong Duan; Alex F Chen; Jun Ren
Influence of gender on intrinsic contractile properties of isolated ventricular myocytes from calmodulin-induced diabetic transgenic mice.
Endocrine research 2003;29(2):227-36.
2003: Jun Ren; Kadon K Hintz; Zamzam K Roughead; Jinhong Duan; Peter B Colligan; Bonnie H Ren; Kap J Lee; Huawei Zeng
Impact of estrogen replacement on ventricular myocyte contractile function and protein kinase B/Akt activation.
American journal of physiology. Heart and circulatory physiology 2003;284(5):H1800-7.
2003: Shaik Shavali; Jun Ren; Manuchair Ebadi
Insulin-like growth factor-1 protects human dopaminergic SH-SY5Y cells from salsolinol-induced toxicity.
Neuroscience letters 2003;340(2):79-82.
2003: Nicholas S Aberle; Jun Ren
Short-term acetaldehyde exposure depresses ventricular myocyte contraction: role of cytochrome P450 oxidase, xanthine oxidase, and lipid peroxidation.
Alcoholism, clinical and experimental research 2003;27(4):577-83.
2003: Jun Ren; Zamzam K Roughead; Loren E Wold; Faye L Norby; Sharlene G Rakoczy; Renee L Mabey; Holly M Brown-Borg
Increases in insulin-like growth factor-1 level and peroxidative damage after gestational ethanol exposure in rats.
Pharmacological research : the official journal of the Italian Pharmacological Society 2003;47(4):341-7.
2003: Nicholas S Aberle II; Midori Hiramatsu; Jun Ren
Japanese herbal medicine Toki-shakuyaku-san (TJ-23) enhances cardiac contractile function in isolated ventricular cardiomyocytes.
Journal of pharmacological sciences 2003;91(3):197-201.
2003: Jun Ren; Jinhong Duan; Kadon K Hintz; Bonnie H Ren
High glucose induces cardiac insulin-like growth factor I resistance in ventricular myocytes: role of Akt and ERK activation.
Cardiovascular research 2003;57(3):738-48.
2003: Gang Ye; Naira S Metreveli; Jun Ren; Paul N Epstein
Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production.
Diabetes 2003;52(3):777-83.
2003: Jinhong Duan; Lucy B Esberg; Gang Ye; Anthony J Borgerding; Bonnie H Ren; Nicholas S Aberle; Paul N Epstein; Jun Ren
Influence of gender on ethanol-induced ventricular myocyte contractile depression in transgenic mice with cardiac overexpression of alcohol dehydrogenase.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2003;134(3):607-14.
2003: Jinhong Duan; Hai-Ying Zhang; Steven D Adkins; Bonnie H Ren; Faye L Norby; Xiaochun Zhang; Joseph N Benoit; Paul N Epstein; Jun Ren
Impaired cardiac function and IGF-I response in myocytes from calmodulin-diabetic mice: role of Akt and RhoA.
American journal of physiology. Endocrinology and metabolism 2003;284(2):E366-76.
2003: Lucy B Esberg; Guei-Jane Wang; Yun-Lian Lin; Jun Ren
Iso-S-petasin, a hypotensive sesquiterpene from Petasites formosanus, depresses cardiac contraction and intracellular Ca2+ transients in adult rat ventricular myocytes.
The Journal of pharmacy and pharmacology 2003;55(1):103-7.
2002: Faye L Norby; Loren E Wold; Jinhong Duan; Kadon K Hintz; Jun Ren
IGF-I attenuates diabetes-induced cardiac contractile dysfunction in ventricular myocytes.
American journal of physiology. Endocrinology and metabolism 2002;283(4):E658-66.
2002: Jun Ren; Bonnie H Ren; Avadhesh C Sharma
Sepsis-induced depressed contractile function of isolated ventricular myocytes is due to altered calcium transient properties.
Shock (Augusta, Ga.) 2002;18(3):285-8.
2002: Kadon K Hintz; Faye L Norby; Jinhong Duan; Michael A Cinnamon; Van A Doze; Jun Ren
Comparison of cardiac excitation-contraction coupling in isolated ventricular myocytes between rat and mouse.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2002;133(1):191-8.
2002: Alex F Chen; Jun Ren; Chao-Yu Miao
Nitric oxide synthase gene therapy for cardiovascular disease.
Japanese journal of pharmacology 2002;89(4):327-36.
2002: Jun Ren; Amy J Davidoff
alpha2-Heremans Schmid glycoprotein, a putative inhibitor of tyrosine kinase, prevents glucose toxicity associated with cardiomyocyte dysfunction.
Diabetes/metabolism research and reviews 2002;18(4):305-10.
2002: Kish L Golden; Jun Ren; Andrea Dean; James D Marsh
Norepinephrine regulates the in vivo expression of the L-type calcium channel.
Molecular and cellular biochemistry 2002;236(1-2):107-14.
2002: Guei-Jane Wang; Xi-Chen Wu; Yun-Lian Lin; Jun Ren; Andrew Yau-Chik Shum; Yu-Yuan Wu; Chieh-Fu Chen
Ca2+ channel blocking effect of iso-S-petasin in rat aortic smooth muscle cells.
European journal of pharmacology 2002;445(3):239-45.
2002: Jun Ren
Short-term administration of insulin-like growth factor I (IGF-1) does not induce myocardial IGF-1 resistance.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2002;12(3):162-8.
2002: RA Brown; Karl J Ilg; Alex F Chen; Jun Ren
Dietary Mg(2+) supplementation restores impaired vasoactive responses in isolated rat aorta induced by chronic ethanol consumption.
European journal of pharmacology 2002;442(3):241-50.
2002: Jun Ren
Influence of genetically predisposed diabetes on ethanol-induced depression of cardiac contraction in adult rat ventricular myocytes.
Experimental physiology 2002;87(3):293-8.
2002: Peter B Colligan; Holly M Brown-Borg; Jinhong Duan; Bonnie H Ren; Jun Ren
Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice.
The Journal of endocrinology 2002;173(2):257-64.
2002: Jun Ren; Holly M Brown-Borg
Impaired cardiac excitation-contraction coupling in ventricular myocytes from Ames dwarf mice with IGF-I deficiency.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2002;12(2):99-105.
2002: Jinhong Duan; Grant E McFadden; Anthony J Borgerding; Faye L Norby; Bonnie H Ren; Gang Ye; Paul N Epstein; Jun Ren
Overexpression of alcohol dehydrogenase exacerbates ethanol-induced contractile defect in cardiac myocytes.
American journal of physiology. Heart and circulatory physiology 2002;282(4):H1216-22.
2002: Faye L Norby; Jun Ren
Anisodamine inhibits cardiac contraction and intracellular Ca(2+) transients in isolated adult rat ventricular myocytes.
European journal of pharmacology 2002;439(1-3):21-5.
2002: Jun Ren; Guei-Jane Wang; Pauline Petrovski; Bonnie H Ren; RA Brown
Influence of hypertension on acetaldehyde-induced vasorelaxation in rat thoracic aorta.
Pharmacological research : the official journal of the Italian Pharmacological Society 2002;45(3):195-9.
2002: RA Brown; Karl J Ilg; Jun Ren
Influence of hypertension on tetrahydropapaveroline-induced vasorelaxation in rat thoracic aorta.
Endocrine research 2002;28(1-2):19-26.
2002: Leigh Anne Turcotte; Nicholas S Aberle; Faye L Norby; Guei-Jane Wang; Jun Ren
Influence of prenatal ethanol exposure on vascular contractile response in rat thoracic aorta.
Alcohol (Fayetteville, N.Y.) 2002;26(2):75-81.
2002: Kadon K Hintz; Jun Ren
Prediabetic insulin resistance is not permissive to the development of cardiac resistance to insulin-like growth factor I in ventricular myocytes.
Diabetes research and clinical practice 2002;55(2):89-98.
2002: Cindy M Anderson; Jun Ren
Leptin, leptin resistance and endothelial dysfunction in pre-eclampsia.
Cellular and molecular biology (Noisy-le-Grand, France) 2002;48 Online Pub():OL323-9.
2002: Peter B Colligan; David P Relling; Jun Ren
Ceramide attenuates high glucose-induced cardiac contractile abnormalities in cultured adult rat ventricular myocytes.
Cellular and molecular biology (Noisy-le-Grand, France) 2002;48 Online Pub():OL251-7.
2002: Jun Ren; Loren E Wold; Melissa Natavio; Bonnie H Ren; John H Hannigan; RA Brown
Influence of prenatal alcohol exposure on myocardial contractile function in adult rat hearts: role of intracellular calcium and apoptosis.
Alcohol and alcoholism (Oxford, Oxfordshire) 2002;37(1):30-7.
2002: Loren E Wold; David P Relling; Jinhong Duan; Faye L Norby; Jun Ren
Abrogated leptin-induced cardiac contractile response in ventricular myocytes under spontaneous hypertension: role of Jak/STAT pathway.
Hypertension 2002;39(1):69-74.
2001: RA Brown; M F Walsh; Jun Ren
Influence of gender and diabetes on vascular and myocardial contractile function.
Endocrine research 2001;27(4):399-408.
2001: Glenda I Scott; Peter B Colligan; Bonnie H Ren; Jun Ren
Ginsenosides Rb1 and Re decrease cardiac contraction in adult rat ventricular myocytes: role of nitric oxide.
British journal of pharmacology 2001;134(6):1159-65.
2001: Loren E Wold; David P Relling; Peter B Colligan; Glenda I Scott; Kadon K Hintz; Bonnie H Ren; Paul N Epstein; Jun Ren
Characterization of contractile function in diabetic hypertensive cardiomyopathy in adult rat ventricular myocytes.
Journal of molecular and cellular cardiology 2001;33(9):1719-26.
2001: RA Brown; P Petrovski; A O Savage; Jun Ren
Influence of ATP-sensitive K+ channel modulation on the mechanical properties of diabetic myocardium.
Endocrine research 2001;27(3):269-81.
2001: L E Wold; Jack T Saari; Jun Ren
Isolated ventricular myocytes from copper-deficient rat hearts exhibit enhanced contractile function.
American journal of physiology. Heart and circulatory physiology 2001;281(2):H476-81.
2001: Kadon K Hintz; Loren E Wold; Peter B Colligan; Glenda I Scott; Kap J Lee; James R Sowers; Jun Ren
Influence of ovariectomy on ventricular myocyte contraction in simulated diabetes.
Journal of biomedical science 2001;8(4):307-13.
2001: Guei-Jane Wang; Andrew Yau-Chik Shum; Yun-Lian Lin; Jyh-Fei Liao; Xi-Chen Wu; Jun Ren; Chieh-Fu Chen
Calcium channel blockade in vascular smooth muscle cells: major hypotensive mechanism of S-petasin, a hypotensive sesquiterpene from Petasites formosanus.
The Journal of pharmacology and experimental therapeutics 2001;297(1):240-6.
2001: Kish L Golden; Jun Ren; Jessica O'Connor; A Dean; Stephen E DiCarlo; James D Marsh
In vivo regulation of Na/Ca exchanger expression by adrenergic effectors.
American journal of physiology. Heart and circulatory physiology 2001;280(3):H1376-82.
2001: RA Brown; M J Anthony; P Petrovski; Jun Ren
The influence of gender, diabetes, and acetaldehyde on the intrinsic contractile properties of isolated rat myocardium.
Cardiovascular toxicology 2001;1(1):35-42.
2001: Loren E Wold; Faye L Norby; Kadon K Hintz; Peter B Colligan; Paul N Epstein; Jun Ren
Prenatal ethanol exposure alters ventricular myocyte contractile function in the offspring of rats: influence of maternal Mg2+ supplementation.
Cardiovascular toxicology 2001;1(3):215-24.
2001: Jun Ren; Melissa Natavio; L Jefferson; M L Pavlik; RA Brown
Loss of cardiac contractile response to tetrahydropapaveroline with advanced age and hypertension.
Cellular and molecular biology (Noisy-le-Grand, France) 2001;47 Online Pub():OL15-22.
2001: John W Phillis; Jun Ren; Michael H O'Regan
Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex.
Journal of neurochemistry 2001;76(1):247-57.
2000: John W Phillis; Jun Ren; Michael H O'Regan
Inhibition of Na(+)/H(+) exchange by 5-(N-ethyl-N-isopropyl)-amiloride reduces free fatty acid efflux from the ischemic reperfused rat cerebral cortex.
Brain research 2000;884(1--2):155-62.
2000: Jun Ren; RA Brown
Influence of chronic alcohol ingestion on acetaldehyde-induced depression of rat cardiac contractile function.
Alcohol and alcoholism (Oxford, Oxfordshire) 2000;35(6):554-60.
2000: M W Nickola; Loren E Wold; Peter B Colligan; G J Wang; W K Samson; Jun Ren
Leptin attenuates cardiac contraction in rat ventricular myocytes. Role of NO.
Hypertension 2000;36(4):501-5.
2000: Jun Ren; James R Sowers; M F Walsh; RA Brown
Reduced contractile response to insulin and IGF-I in ventricular myocytes from genetically obese Zucker rats.
American journal of physiology. Heart and circulatory physiology 2000;279(4):H1708-14.
2000: Jun Ren; M F Walsh; L Jefferson; Melissa Natavio; K J Ilg; James R Sowers; RA Brown
Basal and ethanol-induced cardiac contractile response in lean and obese Zucker rat hearts.
Journal of biomedical science 2000;7(5):390-400.
2000: LL Guyot; Fernando G Diaz; Michael H O'Regan; Jun Ren; John W Phillis
The effect of intravenous insulin on accumulation of excitotoxic and other amino acids in the ischemic rat cerebral cortex.
Neuroscience letters 2000;288(1):61-5.
2000: Jun Ren; A M Bode
Altered cardiac excitation-contraction coupling in ventricular myocytes from spontaneously diabetic BB rats.
American journal of physiology. Heart and circulatory physiology 2000;279(1):H238-44.
2000: John W Phillis; Jun Ren; Michael H O'Regan
Transporter reversal as a mechanism of glutamate release from the ischemic rat cerebral cortex: studies with DL-threo-beta-benzyloxyaspartate.
Brain research 2000;868(1):105-12.
2000: Jun Ren; B W Smude; M L Pavlik; RA Brown
Diminished cardiac contractile response to tetrahydropapaveroline in hypertension: role of beta-adrenoceptors and intracellular Ca(2+).
Alcohol (Fayetteville, N.Y.) 2000;21(2):149-59.
2000: Kish L Golden; Q Ivy Fan; B Chen; Jun Ren; Jessica O'Connor; James D Marsh
Adrenergic stimulation regulates Na(+)/Ca(2+)Exchanger expression in rat cardiac myocytes.
Journal of molecular and cellular cardiology 2000;32(4):611-20.
2000: Jun Ren
Attenuated cardiac contractile responsiveness to insulin-like growth factor I in ventricular myocytes from biobreeding spontaneous diabetic rats.
Cardiovascular research 2000;46(1):162-71.
2000: Jun Ren; Loren E Wold; Paul N Epstein
Diabetes enhances acetaldehyde-induced depression of cardiac myocyte contraction.
Biochemical and biophysical research communications 2000;269(3):697-703.
1999: Jun Ren; L Jefferson; James R Sowers; RA Brown
Influence of age on contractile response to insulin-like growth factor 1 in ventricular myocytes from spontaneously hypertensive rats.
Hypertension 1999;34(6):1215-22.
1999: Jun Ren; L Zhang; Christina G Benishin
Parathyroid hypertensive factor inhibits voltage-gated K+ channels in vascular smooth muscle cells.
Canadian journal of physiology and pharmacology 1999;77(11):860-5.
1999: Jun Ren; W K Samson; James R Sowers
Insulin-like growth factor I as a cardiac hormone: physiological and pathophysiological implications in heart disease.
Journal of molecular and cellular cardiology 1999;31(11):2049-61.
1999: Jun Ren; L J Dominguez; James R Sowers; Amy J Davidoff
Metformin but not glyburide prevents high glucose-induced abnormalities in relaxation and intracellular Ca2+ transients in adult rat ventricular myocytes.
Diabetes 1999;48(10):2059-65.
1999: Jun Ren; RA Brown
Hypertension augments ethanol-induced depression of cell shortening and intracellular Ca(2+) transients in adult rat ventricular myocytes.
Biochemical and biophysical research communications 1999;261(1):202-8.
1999: RA Brown; L Jefferson; N Sudan; T C Lloyd; Jun Ren
Acetaldehyde depresses myocardial contraction and cardiac myocyte shortening in spontaneously hypertensive rats: role of intracellular Ca2+.
Cellular and molecular biology (Noisy-le-Grand, France) 1999;45(4):453-65.
1999: Jun Ren; James R Sowers; M Natavio; RA Brown
Influence of age on inotropic response to insulin and insulin-like growth factor I in spontaneously hypertensive rats: role of nitric oxide.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1999;221(1):46-52.
1999: Jun Ren; Mary F Walsh; M Hamaty; James R Sowers; RA Brown
Augmentation of the inotropic response to insulin in diabetic rat hearts.
Life sciences 1999;65(4):369-80.
1998: RA Brown; M Crawford; M Natavio; P Petrovski; Jun Ren
Dietary magnesium supplementation attenuates ethanol-induced myocardial dysfunction.
Alcoholism, clinical and experimental research 1998;22(9):2062-72.
1998: Jun Ren; Mary F Walsh; M Hamaty; James R Sowers; RA Brown
Altered inotropic response to IGF-I in diabetic rat heart: influence of intracellular Ca2+ and NO.
The American journal of physiology 1998;275(3 Pt 2):H823-30.
1997: Jun Ren; Gary Gintant; R E Miller; Amy J Davidoff
High extracellular glucose impairs cardiac E-C coupling in a glycosylation-dependent manner.
The American journal of physiology 1997;273(6 Pt 2):H2876-83.
1997: Jun Ren; Amy J Davidoff; RA Brown
Acetaldehyde depresses shortening and intracellular Ca2+ transients in adult rat ventricular myocytes.
Cellular and molecular biology (Noisy-le-Grand, France) 1997;43(6):825-34.
1997: Amy J Davidoff; Jun Ren
Low insulin and high glucose induce abnormal relaxation in cultured adult rat ventricular myocytes.
The American journal of physiology 1997;272(1 Pt 2):H159-67.
1997: Jun Ren; Amy J Davidoff
Diabetes rapidly induces contractile dysfunctions in isolated ventricular myocytes.
The American journal of physiology 1997;272(1 Pt 2):H148-58.
1996: Jun Ren; L J Dominguez; James R Sowers; Amy J Davidoff
Troglitazone attenuates high-glucose-induced abnormalities in relaxation and intracellular calcium in rat ventricular myocytes.
Diabetes 1996;45(12):1822-5.
1996: Jun Ren; Edward Karpinski; Christina G Benishin
The actions of prostaglandin E2 on potassium currents in rat tail artery vascular smooth muscle cells: regulation by protein kinase A and protein kinase C.
The Journal of pharmacology and experimental therapeutics 1996;277(1):394-402.
1995: Jun Ren; Edward Karpinski; Christina G Benishin
Prostaglandin E2 contracts vascular smooth muscle and inhibits potassium currents in vascular smooth muscle cells of rat tail artery.
The Journal of pharmacology and experimental therapeutics 1995;275(2):710-9.
1994: Jun Ren; Christina G Benishin
Evidence that prostaglandin E2 can block calcium-activated 86Rb efflux from rat brain synaptosomes via a protein kinase C-dependent mechanism.
Journal of neurochemistry 1994;62(5):1840-6.
1994: Jun Ren; Edward Karpinski; Christina G Benishin
Inhibition of a K+ current by beta-dendrotoxin in primary and subcultured vascular smooth muscle cells.
The Journal of pharmacology and experimental therapeutics 1994;269(1):209-14.