Andrew Renwick

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Renwick A G; Walker R
Risk assessment of micronutrients.
Renwick A G; Tarka S M
Microbial hydrolysis of steviol glycosides.
Renwick A G
The use of a sweetener substitution method to predict dietary exposures for the intense sweetener rebaudioside A.

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2008: Renwick A G; Walker R
Risk assessment of micronutrients.
Toxicology letters 2008;180(2):123-30.
2008: Renwick A G; Tarka S M
Microbial hydrolysis of steviol glycosides.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46 Suppl 7():S70-4.
2008: Renwick A G
The use of a sweetener substitution method to predict dietary exposures for the intense sweetener rebaudioside A.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46 Suppl 7():S61-9.
2008: Renwick A G
Re: The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(3):1206-7; author reply 1208-9.
2008: Renwick Andrew G; Dragsted Lars O; Fletcher Reg J; Flynn Albert; Scott John M; Tuijtelaars Sandra; Wildemann T
Minimising the population risk of micronutrient deficiency and over-consumption: a new approach using selenium as an example.
European journal of nutrition 2008;47(1):17-25.
2007: Kroes R; Renwick A G; Feron V; Galli C L; Gibney M; Greim H; Guy R H; Lhuguenot J C; van de Sandt J J M
Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(12):2533-62.
2007: Renwick A G; Nordmann H
First European conference on aspartame: putting safety and benefits into perspective. Synopsis of presentations and conclusions.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(7):1308-13.
2006: Barlow S; Renwick A G; Kleiner J; Bridges J W; Busk L; Dybing E; Edler L; Eisenbrand G; Fink-Gremmels J; Knaap A; Kroes R; Liem D; Müller D J G; Page S; Rolland V; Schlatter J; Tritscher A; Tueting W; Würtzen G
Risk assessment of substances that are both genotoxic and carcinogenic report of an International Conference organized by EFSA and WHO with support of ILSI Europe.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(10):1636-50.
2006: O'Brien J; Renwick A G; Constable A; Dybing E; Müller D J G; Schlatter J; Slob W; Tueting W; van Benthem J; Williams G M; Wolfreys A
Approaches to the risk assessment of genotoxic carcinogens in food: a critical appraisal.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(10):1613-35.
2006: Renwick Andrew G
The intake of intense sweeteners - an update review.
Food additives and contaminants 2006;23(4):327-38.
2006: Renwick A G
Toxicology of micronutrients: adverse effects and uncertainty.
The Journal of nutrition 2006;136(2):493S-501S.
2005: Renwick A G
Structure-based thresholds of toxicological concern--guidance for application to substances present at low levels in the diet.
Toxicology and applied pharmacology 2005;207(2 Suppl):585-91.
2005: Dorne J L C M; Renwick A G
The refinement of uncertainty/safety factors in risk assessment by the incorporation of data on toxicokinetic variability in humans.
Toxicological sciences : an official journal of the Society of Toxicology 2005;86(1):20-6.
2005: Renwick Andrew G; Walker Ronald
The Fourth Workshop on the Assessment of Adequate Intake of Dietary Amino Acids: general discussion of session 3 and overall workshop discussion.
The Journal of nutrition 2005;135(6 Suppl):1602S-6S.
2005: Dorne J L C M; Walton K; Renwick A G
Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(2):203-16.
2004: Renwick A G; Flynn A; Fletcher R J; Müller D J G; Tuijtelaars S; Verhagen H
Risk-benefit analysis of micronutrients.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(12):1903-22.
2004: Renwick Andrew G
Establishing the upper end of the range of adequate and safe intakes for amino acids: a toxicologist's viewpoint.
The Journal of nutrition 2004;134(6 Suppl):1617S-1624S; discussion 1630S-1632S, 1667S-1672S.
2004: Renwick A G; Thompson J P; O'Shaughnessy M; Walter E J
The metabolism of cyclamate to cyclohexylamine in humans during long-term administration.
Toxicology and applied pharmacology 2004;196(3):367-80.
2004: Renwick A G
Toxicology databases and the concept of thresholds of toxicological concern as used by the JECFA for the safety evaluation of flavouring agents.
Toxicology letters 2004;149(1-3):223-34.
2004: Renwick A G
Risk characterisation of chemicals in food.
Toxicology letters 2004;149(1-3):163-76.
2004: Dorne J L C M; Walton K; Renwick A G
Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation).
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(3):397-421.
2004: Dorne J L C M; Walton K; Renwick A G
Human variability in the renal elimination of foreign compounds and renal excretion-related uncertainty factors for risk assessment.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(2):275-98.
2004: Walton K; Dorne J L C M; Renwick A G
Species-specific uncertainty factors for compounds eliminated principally by renal excretion in humans.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(2):261-74.
2004: Kroes R; Renwick A G; Cheeseman M; Kleiner J; Mangelsdorf I; Piersma A; Schilter B; Schlatter J; van Schothorst F; Vos J G; Würtzen G;
Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(1):65-83.
2003: Schilter B; Andersson C; Anton R; Constable A; Kleiner J; O'Brien J; Renwick A G; Korver O; Smit F; Walker R;
Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplements.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2003;41(12):1625-49.
2003: Renwick A G; Barlow S M; Hertz-Picciotto I; Boobis A R; Dybing E; Edler L; Eisenbrand G; Greig J B; Kleiner J; Lambe J; Müller D J G; Smith M R; Tritscher A; Tuijtelaars S; van den Brandt P A; Walker R; Kroes R
Risk characterisation of chemicals in food and diet.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2003;41(9):1211-71.
2003: Renwick Andrew G
The safety testing of amino acids.
The Journal of nutrition 2003;133(6 Suppl 1):2031S-2033S.
2003: Dorne J L C M; Walton K; Renwick A G
Polymorphic CYP2C19 and N-acetylation: human variability in kinetics and pathway-related uncertainty factors.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2003;41(2):225-45.
2003: Dorne J L C M; Walton K; Renwick A G
Human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for risk assessment.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2003;41(2):201-24.
2002: Dorne J L C M; Walton K; Slob W; Renwick A G
Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(11):1633-56.
2002: Renwick Andrew G
Pesticide residue analysis and its relationship to hazard characterisation (ADI/ARfD) and intake estimations (NEDI/NESTI).
Pest management science 2002;58(10):1073-82.
2002: Dybing E; Doe J; Groten J; Kleiner J; O'Brien J; Renwick A G; Schlatter J; Steinberg P; Tritscher A; Walker R; Younes M
Hazard characterisation of chemicals in food and diet. dose response, mechanisms and extrapolation issues.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(2-3):237-82.
2001: Walton K; Dorne J L; Renwick A G
Uncertainty factors for chemical risk assessment: interspecies differences in glucuronidation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2001;39(12):1175-90.
2001: Dorne J L; Walton K; Renwick A G
Human variability in glucuronidation in relation to uncertainty factors for risk assessment.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2001;39(12):1153-73.
2001: Dorne J L; Walton K; Renwick A G
Uncertainty factors for chemical risk assessment. human variability in the pharmacokinetics of CYP1A2 probe substrates.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2001;39(7):681-96.
2001: Walton K; Dorne J L; Renwick A G
Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2001;39(7):667-80.
2001: Renwick A G; Walton K
The use of surrogate endpoints to assess potential toxicity in humans.
Toxicology letters 2001;120(1-3):97-110.
2000: Renwick A G
The use of safety or uncertainty factors in the setting of acute reference doses.
Food additives and contaminants 2000;17(7):627-35.
2000: Renwick A G; Dorne J L; Walton K
An analysis of the need for an additional uncertainty factor for infants and children.
Regulatory toxicology and pharmacology : RTP 2000;31(3):286-96.
2000: Sims J; Roberts A; Daniel J W; Renwick A G
The metabolic fate of sucralose in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2000;38 Suppl 2():S115-21.
2000: Roberts A; Renwick A G; Sims J; Snodin D J
Sucralose metabolism and pharmacokinetics in man.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2000;38 Suppl 2():S31-41.
1999: Renwick A G
Incidence and severity in relation to magnitude of intake above the ADI or TDI: use of critical effect data.
Regulatory toxicology and pharmacology : RTP 1999;30(2 Pt 2):S79-86.
1999: Renwick A G
Duration of intake above the ADI/TDI in relation to toxicodynamics and toxicokinetics.
Regulatory toxicology and pharmacology : RTP 1999;30(2 Pt 2):S69-78.
1999: Renwick A G
The metabolism of antihistamines and drug interactions: the role of cytochrome P450 enzymes.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29 Suppl 3():116-24.
1999: Renwick A G
Intake of intense sweeteners.
World review of nutrition and dietetics 1999;85():178-200.
1998: Renwick A G; Lazarus N R
Human variability and noncancer risk assessment--an analysis of the default uncertainty factor.
Regulatory toxicology and pharmacology : RTP 1998;27(1 Pt 1):3-20.
1998: Renwick A G
Toxicokinetics in infants and children in relation to the ADI and TDI.
Food additives and contaminants 1998;15 Suppl():17-35.
1996: Tembe E A; Honeywell R; Buss N E; Renwick A G
All-trans-retinoic acid in maternal plasma and teratogenicity in rats and rabbits.
Toxicology and applied pharmacology 1996;141(2):456-72.
1996: Renwick A G
Needs and methods for priority setting for estimating the intake of food additives.
Food additives and contaminants 1996;13(4):467-75.
1996: Summers Q A; Fleming J S; Dai Y; Perring S; Honeywell R; Gough K J; Renwick A G; Clark A R; Nassim M A; Holgate S T
The pulmonary deposition of two aerosol preparations of nedocromil sodium delivered by MDI assessed by single photon emission computed tomography.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 1996;9 Suppl 1():S93-109.
1995: Renwick A G
The use of an additional safety or uncertainty factor for nature of toxicity in the estimation of acceptable daily intake and tolerable daily intake values.
Regulatory toxicology and pharmacology : RTP 1995;22(3):250-61.
1995: Roberts J; Waller D G; O'Shea N; Macklin B S; Renwick A G
The effect of selegiline on the peripheral pharmacokinetics of levodopa in young volunteers.
British journal of clinical pharmacology 1995;40(4):404-6.
1995: Rashid T J; Martin U; Clarke H; Waller D G; Renwick A G; George C F
Factors affecting the absolute bioavailability of nifedipine.
British journal of clinical pharmacology 1995;40(1):51-8.
1995: Lee S C; Renwick A G
Sulphoxide reduction by rat intestinal flora and by Escherichia coli in vitro.
Biochemical pharmacology 1995;49(11):1567-76.
1995: Lee S C; Renwick A G
Sulphoxide reduction by rat and rabbit tissues in vitro.
Biochemical pharmacology 1995;49(11):1557-65.
1994: Buss N E; Tembe E A; Prendergast B D; Renwick A G; George C F
The teratogenic metabolites of vitamin A in women following supplements and liver.
Human & experimental toxicology 1994;13(1):33-43.
1994: Renwick A G
Intense sweeteners, food intake, and the weight of a body of evidence.
Physiology & behavior 1994;55(1):139-43.
1993: Renwick A G; Walker R
An analysis of the risk of exceeding the acceptable or tolerable daily intake.
Regulatory toxicology and pharmacology : RTP 1993;18(3):463-80.
1993: Rashid J; McKinstry C; Renwick A G; Dirnhuber M; Waller D G; George C F
Quercetin, an in vitro inhibitor of CYP3A, does not contribute to the interaction between nifedipine and grapefruit juice.
British journal of clinical pharmacology 1993;36(5):460-3.
1993: Ahsan C H; Renwick A G; Waller D G; Challenor V F; George C F; Amanullah M
The influence of dose and ethnic origins on the pharmacokinetics of nifedipine.
Clinical pharmacology and therapeutics 1993;54(3):329-38.
1993: Renwick A G
A data-derived safety (uncertainty) factor for the intense sweetener, saccharin.
Food additives and contaminants 1993;10(3):337-50.
1993: Renwick A G
Data-derived safety factors for the evaluation of food additives and environmental contaminants.
Food additives and contaminants 1993;10(3):275-305.
1992: Renwick A G; Ahsan C H; Challenor V F; Daniels R; Macklin B S; Waller D G; George C F
The influence of posture on the pharmacokinetics of orally administered nifedipine.
British journal of clinical pharmacology 1992;34(4):332-6.
1992: Buss N E; Renwick A G
Blood pressure changes and sympathetic function in rats given cyclohexylamine by intravenous infusion.
Toxicology and applied pharmacology 1992;115(2):211-5.
1992: Buss N E; Renwick A G; Donaldson K M; George C F
The metabolism of cyclamate to cyclohexylamine and its cardiovascular consequences in human volunteers.
Toxicology and applied pharmacology 1992;115(2):199-210.
1992: Summers Q A; Singh S; Honeywell R G; Renwick A G; Holgate S T
The effect of respiratory manoeuvres and pharmacological agents on the pharmacokinetics of nedocromil sodium after inhalation.
British journal of clinical pharmacology 1992;33(4):431-8.
1992: Robertson D R; Renwick A G; Macklin B; Jones S; Waller D G; George C F; Fleming J S
The influence of levodopa on gastric emptying in healthy elderly volunteers.
European journal of clinical pharmacology 1992;42(4):409-12.
1991: Waller D G; Usman F; Renwick A G; Macklin B; George C F
Oral amino acids and gastric emptying: an investigation of the mechanism of levodopa-induced gastric stasis.
British journal of clinical pharmacology 1991;32(6):771-3.
1991: Waller D G; Roseveare C; Renwick A G; Macklin B; George C F
Gastric emptying in healthy volunteers after multiple doses of levodopa.
British journal of clinical pharmacology 1991;32(6):691-5.
1991: Heaton G D; Renwick A G
The effects of high dietary concentrations of saccharin on in vitro metabolism of xenobiotics in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1991;29(5):297-303.
1991: Heaton G D; Renwick A G
The effects of high dietary concentrations of sodium saccharin on in vivo metabolism of xenobiotics in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1991;29(5):305-12.
1991: Robertson D R; Higginson I; Macklin B S; Renwick A G; Waller D G; George C F
The influence of protein containing meals on the pharmacokinetics of levodopa in healthy volunteers.
British journal of clinical pharmacology 1991;31(4):413-7.
1991: Ahsan C H; Renwick A G; Macklin B; Challenor V F; Waller D G; George C F
Ethnic differences in the pharmacokinetics of oral nifedipine.
British journal of clinical pharmacology 1991;31(4):399-403.
1991: Renwick A G
Safety factors and establishment of acceptable daily intakes.
Food additives and contaminants 1991;8(2):135-49.
1990: Renwick A G
Acceptable daily intake and the regulation of intense sweeteners.
Food additives and contaminants 1990;7(4):463-75.
1990: Oliver R M; Upward J W; Dewhurst A G; Honeywell R; Renwick A G; Waller D G
The pharmacokinetics of doxazosin in patients with hypertension and renal impairment.
British journal of clinical pharmacology 1990;29(4):417-22.
1990: Robertson D R; Renwick A G; Wood N D; Cross N; Macklin B S; Fleming J S; Waller D G; George C F
The influence of levodopa on gastric emptying in man.
British journal of clinical pharmacology 1990;29(1):47-53.
1990: Summers Q A; Honeywell R; Renwick A G; Holgate S T
The protective efficacy of inhaled, oral and intravenous nedocromil sodium against adenosine-5'-monophosphate-induced bronchoconstriction in asthmatic volunteers.
Pulmonary pharmacology 1990;3(4):190-7.
1989: Challenor V F; Waller D G; Renwick A G; George C F
Slow release nifedipine plus atenolol in chronic stable angina pectoris.
British journal of clinical pharmacology 1989;28(5):509-16.
1989: Robertson D R; Wood N D; Everest H; Monks K; Waller D G; Renwick A G; George C F
The effect of age on the pharmacokinetics of levodopa administered alone and in the presence of carbidopa.
British journal of clinical pharmacology 1989;28(1):61-9.
1989: Roberts A; Renwick A G; Ford G; Creasy D M; Gaunt I
The metabolism and testicular toxicity of cyclohexylamine in rats and mice during chronic dietary administration.
Toxicology and applied pharmacology 1989;98(2):216-29.
1989: Roberts A; Renwick A G
The pharmacokinetics and tissue concentrations of cyclohexylamine in rats and mice.
Toxicology and applied pharmacology 1989;98(2):230-42.
1988: Richards R; Simpson S F; Renwick A G; Holgate S T
Inhalation rate of sodium cromoglycate determines plasma pharmacokinetics and protection against AMP-induced bronchoconstriction in asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1988;1(10):896-901.
1988: Renwick A G; Robertson D R; Macklin B; Challenor V; Waller D G; George C F
The pharmacokinetics of oral nifedipine--a population study.
British journal of clinical pharmacology 1988;25(6):701-8.
1988: Renwick A G; Thakrar A; Lawrie C A; George C F
Microbial amino acid metabolites and bladder cancer: no evidence of promoting activity in man.
Human toxicology 1988;7(3):267-72.
1988: Robertson D R; Waller D G; Renwick A G; George C F
Age-related changes in the pharmacokinetics and pharmacodynamics of nifedipine.
British journal of clinical pharmacology 1988;25(3):297-305.
1987: Lawrie C A; Renwick A G
The effect of saccharin ingestion on the excretion of microbial amino acid metabolites in rat and man.
Toxicology and applied pharmacology 1987;91(3):415-28.
1987: Challenor V F; Waller D G; Renwick A G; Gruchy B S; George C F
The trans-hepatic extraction of nifedipine.
British journal of clinical pharmacology 1987;24(4):473-7.
1987: Challenor V F; Waller D G; Gruchy B S; Renwick A G; George C F
Food and nifedipine pharmacokinetics.
British journal of clinical pharmacology 1987;23(2):248-9.
1987: Renwick A G; Le Vie J; Challenor V F; Waller D G; Gruchy B; George C F
Factors affecting the pharmacokinetics of nifedipine.
European journal of clinical pharmacology 1987;32(4):351-5.
1986: Challenor V; Waller D G; Gruchy B S; Renwick A G; George C F; McMurdo E T; McEwen J
The effects of food and posture on the pharmacokinetics of a biphasic release preparation of nifedipine.
British journal of clinical pharmacology 1986;22(5):565-70.
1984: Waller D G; Renwick A G; Gruchy B S; George C F
The first pass metabolism of nifedipine in man.
British journal of clinical pharmacology 1984;18(6):951-4.

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