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Roland Repp

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P Glorius; Martin Gramatzki; Andreas Humpe; C Kellner; F Nimmerjahn; Paul W H I Parren; Roland Repp; M Staudinger; M Stauch; Thomas Valerius; J G J van de Winkel; A Baerenwaldt; F J Beurskens; Michael Dechant; Matthias Peipp
The novel tribody [(CD20)(2)xCD16] efficiently triggers effector cell-mediated lysis of malignant B cells.
Christian Kellner; Tina Maurer; Paul W H I Parren; Martin Gramatzki; Daniela Hallack; Andreas Humpe; Roland Repp; Thomas Valerius; Jan G J van de Winkel; Matthias Peipp
Mimicking an induced self phenotype by coating lymphomas with the NKp30 ligand B7-H6 promotes NK cell cytotoxicity.
Mathias Witzens-Harig; M Zaiss; J Atta; C Buske; G Hess; U Keller; P Kiewe; H Kirchner; Paul La Rosée; G Lenz; H Pelz; Christiane Pott; M Reiser; Roland Repp; C Scholz; A Viardot; Martin Dreyling
Current treatment of mantle cell lymphoma: results of a national survey and consensus meeting.

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All Publications

2013: P Glorius; Martin Gramatzki; Andreas Humpe; C Kellner; F Nimmerjahn; Paul W H I Parren; Roland Repp; M Staudinger; M Stauch; Thomas Valerius; J G J van de Winkel; A Baerenwaldt; F J Beurskens; Michael Dechant; Matthias Peipp
The novel tribody [(CD20)(2)xCD16] efficiently triggers effector cell-mediated lysis of malignant B cells.
Leukemia 2013;27(1):190-201.
2012: Christian Kellner; Tina Maurer; Paul W H I Parren; Martin Gramatzki; Daniela Hallack; Andreas Humpe; Roland Repp; Thomas Valerius; Jan G J van de Winkel; Matthias Peipp
Mimicking an induced self phenotype by coating lymphomas with the NKp30 ligand B7-H6 promotes NK cell cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(10):5037-46.
2012: Mathias Witzens-Harig; M Zaiss; J Atta; C Buske; G Hess; U Keller; P Kiewe; H Kirchner; Paul La Rosée; G Lenz; H Pelz; Christiane Pott; M Reiser; Roland Repp; C Scholz; A Viardot; Martin Dreyling
Current treatment of mantle cell lymphoma: results of a national survey and consensus meeting.
Annals of hematology 2012;91(11):1765-72.
2012: Sahar Mohseni Nodehi; Matthias Peipp; Roland Repp; Natalie Schub; Matthias Staudinger; Joachim Bräutigam; Martin Gramatzki; Christian Kellner; Andreas Humpe
Enhanced ADCC activity of affinity maturated and Fc-engineered mini-antibodies directed against the AML stem cell antigen CD96.
PloS one 2012;7(8):e42426.
2011: Roland Repp; Matthias Staudinger; Thomas Valerius; Patrick H C Van Berkel; Jan G J van de Winkel; Sahar Mohseni Nodehi; Dalia Akramiene; Michael Dechant; Georg H Fey; Pia Glorius; Martin Gramatzki; Christian Kellner; Anja Muskulus; Paul W H I Parren; Matthias Peipp
Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC.
Journal of immunological methods 2011;373(1-2):67-78.
2010: Yvonne Guettinger; Karin Barbin; Matthias Peipp; Joerg Bruenke; Michael Dechant; Heike Horner; Doreen Thierschmidt; Thomas Valerius; Roland Repp; Georg H Fey; Bernhard Stockmeyer
A recombinant bispecific single-chain fragment variable specific for HLA class II and Fc alpha RI (CD89) recruits polymorphonuclear neutrophils for efficient lysis of malignant B lymphoid cells.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(3):1210-7.
2008: Stephan T Becker; Jörg Wiltfang; Wolfram Klapper; Roland Repp; Nektarios Sinis; Patrick H Warnke
Massive swelling of the cervical region: an uncommon manifestation of B cell chronic lymphocytic leukemia.
Oral and maxillofacial surgery 2008;12(4):205-8.
2008: Holly M Horton; Matthew J Bernett; Erik Pong; Matthias Peipp; Sher Karki; Seung Y Chu; John O Richards; Igor Vostiar; Patrick F Joyce; Roland Repp; John Desjarlais; Eugene A Zhukovsky
Potent in vitro and in vivo activity of an Fc-engineered anti-CD19 monoclonal antibody against lymphoma and leukemia.
Cancer research 2008;68(19):8049-57.
2008: Matthias Peipp; Jeroen J Lammerts van Bueren; Tanja Schneider-Merck; Wim W K Bleeker; Michael Dechant; Thomas Beyer; Roland Repp; Patrick H C Van Berkel; Tom Vink; Jan G J van de Winkel; Paul W H I Parren; Thomas Valerius
Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells.
Blood 2008;112(6):2390-9.
2008: Frank P Kroschinsky; Ulrike Schäkel; Rainer Fischer; Brigitte Mohr; Uta Oelschlaegel; Roland Repp; Markus Schaich; Silke Soucek; Gustavo Baretton; Gerhard Ehninger; Christian Thiede
Cup-like acute myeloid leukemia: new disease or artificial phenomenon?
Haematologica 2008;93(2):283-6.
2007: Heike Horner; Carola Frank; Claudia Dechant; Roland Repp; Martin J Glennie; Martin Herrmann; Bernhard Stockmeyer
Intimate cell conjugate formation and exchange of membrane lipids precede apoptosis induction in target cells during antibody-dependent, granulocyte-mediated cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(1):337-45.
2006: Roswitha Forstpointner; Michael Unterhalt; Martin Dreyling; Hans-Peter Böck; Roland Repp; Hannes Wandt; Christiane Pott; John F Seymour; Bernd Metzner; Annette Hänel; Tanja Lehmann; Frank Hartmann; Hermann Einsele; Wolfgang Hiddemann
Maintenance therapy with rituximab leads to a significant prolongation of response duration after salvage therapy with a combination of rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) in patients with recurring and refractory follicular and mantle cell lymphomas: Results of a prospective randomized study of the German Low Grade Lymphoma Study Group (GLSG).
Blood 2006;108(13):4003-8.
2006: Silke F Fischer; Katja Schmidt; Nicola Fiedler; Dieter Glebe; Christian G Schüttler; Jianguang Sun; Wolfram H Gerlich; Roland Repp; Stephan Schaefer
Genotype-dependent activation or repression of HBV enhancer II by transcription factor COUP-TF1.
World journal of gastroenterology : WJG 2006;12(37):6054-8.
2006: Juergen Rech; Roland Repp; Dorit Rech; Bernhard Stockmeyer; Michael Dechant; Gerald Niedobitek; Martin Gramatzki; Thomas Valerius
A humanized HLA-DR antibody (hu1D10, apolizumab) in combination with granulocyte colony-stimulating factor (filgrastim) for the treatment of non-Hodgkin's lymphoma: a pilot study.
Leukemia & lymphoma 2006;47(10):2147-54.
2006: Sandra J Strauss; Franck Morschhauser; Juergen Rech; Roland Repp; Philippe Solal-Celigny; Pier Luigi Zinzani; Andreas Engert; Bertrand Coiffier; Dieter F Hoelzer; William A Wegener; Nick K W Teoh; David M Goldenberg; T Andrew Lister
Multicenter phase II trial of immunotherapy with the humanized anti-CD22 antibody, epratuzumab, in combination with rituximab, in refractory or recurrent non-Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(24):3880-6.
2006: Markus Metzler; Dieter K Luedecke; Wolfgang Saeger; Annette Grueters; Hannes Haberl; Wieland Kiess; Roland Repp; Wolfgang Rascher; Joerg Doetsch
Low prevalence of Gs alpha mutations in śomatotroph adenomas of children and adolescents.
Cancer genetics and cytogenetics 2006;166(2):146-51.
2006: Michael Schwemmlein; Matthias Peipp; Karin Barbin; Domenica Saul; Bernhard Stockmeyer; Roland Repp; Josef Birkmann; Fuat Oduncu; Bertold Emmerich; Georg H Fey
A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells.
British journal of haematology 2006;133(2):141-51.
2005: Norbert Blank; Roland Repp; Wolfgang Römer; Joachim R Kalden; Gisela Helm; Thomas Harrer; Hanns-Martin Lorenz; Rolf Janka
Multiple bone lesions of systemic multifocal fibrosclerosis.
AJR. American journal of roentgenology 2005;185(3):668-70.
2005: Joerg Bruenke; Karin Barbin; Susanne Kunert; Peter Lang; Matthias Pfeiffer; Kristin Stieglmaier; Dietrich Niethammer; Bernhard Stockmeyer; Matthias Peipp; Roland Repp; Thomas Valerius; Georg H Fey
Effective lysis of lymphoma cells with a stabilised bispecific single-chain Fv antibody against CD19 and FcgammaRIII (CD16).
British journal of haematology 2005;130(2):218-28.
2004: Thorben Kracht; Martin Schrappe; Sabine Strehl; Alfred Reiter; Holger-Andreas Elsner; Jan Trka; Gunnar Cario; Susanne Viehmann; Jochen Harbott; Arndt Borkhardt; Markus Metzler; Thorsten Langer; Roland Repp; Rolf Marschalek; Karl Welte; Oskar A Haas; Martin Stanulla
NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms.
Haematologica 2004;89(12):1492-7.
2004: Roswitha Forstpointner; Martin Dreyling; Roland Repp; Sandra Hermann; Annette Hänel; Bernd Metzner; Christiane Pott; Frank Hartmann; Frank Rothmann; Robert Rohrberg; Hans-Peter Böck; Hannes Wandt; Michael Unterhalt; Wolfgang Hiddemann
The addition of rituximab to a combination of fludarabine, cyclophosphamide, mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group.
Blood 2004;104(10):3064-71.
2004: Markus Metzler; Pamela L Strissel; Reiner Strick; Charlotte Niemeyer; Silja Roettgers; Arndt Borkhardt; Jochen Harbott; Wolf D Ludwig; Martin Stanulla; Martin Schrappe; Dirk Reinhardt; Ursula Creutzig; Jörn D Beck; Wolfgang Rascher; Roland Repp; Thorsten Langer
Emergence of translocation t(9;11)-positive leukemia during treatment of childhood acute lymphoblastic leukemia.
Genes, chromosomes & cancer 2004;41(3):291-6.
2004: Markus Schaich; Rainer Koch; Silke Soucek; Roland Repp; Gerhard Ehninger; Thomas Illmer
A sensitive model for prediction of relapse in adult acute myeloid leukaemia with t(8;21) using white blood cell count, CD56 and MDR1 gene expression at diagnosis.
British journal of haematology 2004;125(4):477-9.
2004: Joerg Bruenke; Barbara Fischer; Karin Barbin; Katja Schreiter; Yvonne Wachter; Kerstin Mahr; Fritz Titgemeyer; Michael Niederweis; Matthias Peipp; Susan J Zunino; Roland Repp; Thomas Valerius; Georg H Fey
A recombinant bispecific single-chain Fv antibody against HLA class II and FcgammaRIII (CD16) triggers effective lysis of lymphoma cells.
British journal of haematology 2004;125(2):167-79.
2004: Oliver Kirschberg; Christian G Schüttler; Roland Repp; Stephan Schaefer
A multiplex-PCR to identify hepatitis B virus--enotypes A-F.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004;29(1):39-43.
2004: Markus Metzler; U Brehm; Thorsten Langer; Susanne Viehmann; Arndt Borkhardt; Martin Stanulla; Martin Schrappe; Jochen Harbott; Jörn D Beck; Wolfgang Rascher; Roland Repp
Asymmetric multiplex-polymerase chain reaction - a high throughput method for detection and sequencing genomic fusion sites in t(4;11).
British journal of haematology 2004;124(1):47-54.
2003: Roland Repp; Heidi H van Ojik; Thomas Valerius; Gerard Groenewegen; G Wieland; C Oetzel; Bernhard Stockmeyer; W Becker; M Eisenhut; H Steininger; YM Deo; Geert H Blijham; Joachim R Kalden; Jan G J van de Winkel; Martin Gramatzki
Phase I clinical trial of the bispecific antibody MDX-H210 (anti-FcgammaRI x anti-HER-2/neu) in combination with Filgrastim (G-CSF) for treatment of advanced breast cancer.
British journal of cancer 2003;89(12):2234-43.
2003: Ina Knerr; Markus Metzler; Charlotte M Niemeyer; Wolfgang Holter; Anja Gerecke; Irith Baumann; Regina Trollmann; Roland Repp
Hematologic features and clinical course of an infant with Pearson syndrome caused by a novel deletion of mitochondrial DNA.
Journal of pediatric hematology/oncology 2003;25(12):948-51.
2003: Bernhard Stockmeyer; Thomas Beyer; Winfried Neuhuber; Roland Repp; Joachim R Kalden; Thomas Valerius; Martin Herrmann
Polymorphonuclear granulocytes induce antibody-dependent apoptosis in human breast cancer cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5124-9.
2003: Udo Meissner; Ida Allabauer; Roland Repp; Wolfgang Rascher; Jörg Dötsch
Inducible expression of hypoxia-inducible factor 1alpha (HIF-1alpha) as a tool for studying HIF-1alpha-dependent gene regulation during normoxia in vitro.
Pharmacology 2003;69(2):74-8.
2003: Roland Repp; U Schaekel; G Helm; Christian Thiede; Silke Soucek; Ulrich Pascheberg; Hannes Wandt; Walter Aulitzky; Heinrich Bodenstein; R Sonnen; H Link; Gerhard Ehninger; Martin Gramatzki
Immunophenotyping is an independent factor for risk stratification in AML.
Cytometry. Part B, Clinical cytometry 2003;53(1):11-9.
2003: Thorsten Langer; Markus Metzler; Dirk Reinhardt; Susanne Viehmann; Arndt Borkhardt; Martin Reichel; Martin Stanulla; Martin Schrappe; Ursula Creutzig; Jörg Ritter; Thomas Leis; Ulla Jacobs; Jochen Harbott; Jörn D Beck; Wolfgang Rascher; Roland Repp
Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides.
Genes, chromosomes & cancer 2003;36(4):393-401.
2002: Michael Dechant; Gestur Vidarsson; Bernhard Stockmeyer; Roland Repp; Martin J Glennie; Martin Gramatzki; Jan G J van de Winkel; Thomas Valerius
Chimeric IgA antibodies against HLA class II effectively trigger lymphoma cell killing.
Blood 2002;100(13):4574-80.
2002: Christian G Schüttler; Nicola Fiedler; Katja Schmidt; Roland Repp; Wolfram H Gerlich; Stephan Schaefer
Suppression of hepatitis B virus enhancer 1 and 2 by hepatitis C virus core protein.
Journal of hepatology 2002;37(6):855-62.
2002: Karin Manger; Bernhard Manger; Roland Repp; M Geisselbrecht; A Geiger; A Pfahlberg; Thomas Harrer; Joachim R Kalden
Definition of risk factors for death, end stage renal disease, and thromboembolic events in a monocentric cohort of 338 patients with systemic lupus erythematosus.
Annals of the rheumatic diseases 2002;61(12):1065-70.
2002: Roswitha Forstpointner; Annette Hänel; Roland Repp; S Hermann; Bernd Metzner; Christiane Pott; Frank Hartmann; Frank Rothmann; Hans-Peter Böck; Hannes Wandt; Michael Unterhalt; Wolfgang Hiddemann
[Increased response rate with rituximab in relapsed and refractory follicular and mantle cell lymphomas -- results of a prospective randomized study of the German Low-Grade Lymphoma Study Group].
Deutsche medizinische Wochenschrift (1946) 2002;127(43):2253-8.
2002: Bernhard Stockmeyer; Martin Schiller; Roland Repp; Hanns-Martin Lorenz; Joachim R Kalden; Martin Gramatzki; Thomas Valerius
Enhanced killing of B lymphoma cells by granulocyte colony-stimulating factor-primed effector cells and Hu1D10--a humanized human leucocyte antigen DR antibody.
British journal of haematology 2002;118(4):959-67.
2002: Karin Manger; Roland Repp; M Jansen; M Geisselbrecht; Ralf Wassmuth; N A C Westerdaal; A Pfahlberg; Bernhard Manger; Joachim R Kalden; Jan G J van de Winkel
Fcgamma receptor IIa, IIIa, and IIIb polymorphisms in German patients with systemic lupus erythematosus: association with clinical symptoms.
Annals of the rheumatic diseases 2002;61(9):786-92.
2002: Markus Schaich; Thomas Illmer; Walter Aulitzky; Heinrich Bodenstein; Michael Clemens; Andreas Neubauer; Roland Repp; Ulrike Schäkel; Silke Soucek; Hannes Wandt; Gerhard Ehninger
Intensified double induction therapy with high dose mitoxantrone, etoposide, m-amsacrine and high dose ara-C for elderly acute myeloid leukemia patients aged 61-65 years.
Haematologica 2002;87(8):808-15.
2002: Jörg Dötsch; Ellen Schoof; Harald O Schöcklmann; Bernhard Brüne; Ina Knerr; Roland Repp; Wolfgang Rascher
Nitric oxide increases adrenomedullin receptor function in rat mesangial cells.
Kidney international 2002;61(5):1707-13.
2002: Ina Knerr; Cornelia Dachert; Ernst Beinder; Markus Metzler; Jörg Dötsch; Roland Repp; Wolfgang Rascher
Adrenomedullin, calcitonin gene-related peptide and their receptors: evidence for a decreased placental mRNA content in preeclampsia and HELLP syndrome.
European journal of obstetrics, gynecology, and reproductive biology 2002;101(1):47-53.
2001: Ellen Schoof; M Girstl; Wolfgang Frobenius; M Kirschbaum; Roland Repp; Ina Knerr; Wolfgang Rascher; Jörg Dötsch
Course of placental 11beta-hydroxysteroid dehydrogenase type 2 and 15-hydroxyprostaglandin dehydrogenase mRNA expression during human gestation.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(2):187-92.
2001: Roland Repp; Thomas Valerius; R Bargou
[Bispecific antibodies in hematology and oncology].
Der Internist 2001;42(6):854-9.
2001: Ina Knerr; Z Nyul; J Miller; WH Rösch; Jörg Dötsch; Roland Repp; W Weidner; Wolfgang Rascher
Increased endothelin-1 and decreased adrenomedullin gene expression in the stenotic tissue of congenital pelvi-ureteric junction obstruction in children.
BJU international 2001;87(7):667-71.
2001: Martin Reichel; E Gillert; I Breitenlohner; Sabine Angermüller; Georg H Fey; Rolf Marschalek; Roland Repp; Johann Greil; Jörn D Beck
Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research.
Leukemia 2001;15(2):286-8.
2001: Bernhard Stockmeyer; D Elsässer; Michael Dechant; Roland Repp; Martin Gramatzki; Martin J Glennie; Jan G J van de Winkel; Thomas Valerius
Mechanisms of G-CSF- or GM-CSF-stimulated tumor cell killing by Fc receptor-directed bispecific antibodies.
Journal of immunological methods 2001;248(1-2):103-11.
2000: Bernhard Stockmeyer; Michael Dechant; Marjolein van Egmond; Alison L Tutt; K Sundarapandiyan; Robert F Graziano; Roland Repp; Joachim R Kalden; Martin Gramatzki; Martin J Glennie; Jan G J van de Winkel; Thomas Valerius
Triggering Fc alpha-receptor I (CD89) recruits neutrophils as effector cells for CD20-directed antibody therapy.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5954-61.
2000: F Schläger; Stephan Schaefer; Markus Metzler; N Gratzki; Fritz H Lampert; Wolfram H Gerlich; Roland Repp
Quantitative DNA fragment analysis for detecting low amounts of hepatitis B virus deletion mutants in highly viremic carriers.
Hepatology (Baltimore, Md.) 2000;32(5):1096-105.
2000: Arndt Borkhardt; SE Bojesen; Oskar A Haas; Uta Fuchs; D Bartelheimer; Ivan F Loncarevic; RM Bohle; Jochen Harbott; Roland Repp; U Jaeger; Susanne Viehmann; T Henn; P Korth; D Scharr; Fritz H Lampert
The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):9168-73.
2000: Peter M Kern; Martin Herrmann; Bernhard Stockmeyer; Joachim R Kalden; Thomas Valerius; Roland Repp
Flow cytometric discrimination between viable neutrophils, apoptotic neutrophils and eosinophils by double labelling of permeabilized blood granulocytes.
Journal of immunological methods 2000;241(1-2):11-8.
1999: E Gillert; Thomas Leis; Roland Repp; Martin Reichel; A Hösch; I Breitenlohner; Sabine Angermüller; Arndt Borkhardt; Jochen Harbott; Fritz H Lampert; F Griesinger; Johann Greil; Georg H Fey; Rolf Marschalek
A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells.
Oncogene 1999;18(33):4663-71.
1999: Jörg Dötsch; Kai-Dietrich Nüsken; Ina Knerr; M Kirschbaum; Roland Repp; Wolfgang Rascher
Leptin and neuropeptide Y gene expression in human placenta: ontogeny and evidence for similarities to hypothalamic regulation.
The Journal of clinical endocrinology and metabolism 1999;84(8):2755-8.
1999: Martin Reichel; E Gillert; I Breitenlohner; Roland Repp; Johann Greil; Jörn D Beck; Georg H Fey; Rolf Marschalek
Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research.
Cancer research 1999;59(14):3357-62.
1999: Ina Knerr; Roland Repp; Jörg Dötsch; N Gratzki; Jörg Hänze; Thomas Kapellen; Wolfgang Rascher
Quantitation of gene expression by real-time PCR disproves a "retroviral hypothesis" for childhood-onset diabetes mellitus.
Pediatric research 1999;46(1):57-60.
1998: D Würflein; Michael Dechant; Bernhard Stockmeyer; Alison L Tutt; P Hu; Roland Repp; Joachim R Kalden; Jan G J van de Winkel; A L Epstein; Thomas Valerius; Martin J Glennie; Martin Gramatzki
Evaluating antibodies for their capacity to induce cell-mediated lysis of malignant B cells.
Cancer research 1998;58(14):3051-8.
1998: Karin Manger; Roland Repp; Bernd M Spriewald; Astrid Rascu; A Geiger; Ralf Wassmuth; N A C Westerdaal; B Wentz; Bernhard Manger; Joachim R Kalden; Jan G J van de Winkel
Fcgamma receptor IIa polymorphism in Caucasian patients with systemic lupus erythematosus: association with clinical symptoms.
Arthritis and rheumatism 1998;41(7):1181-9.
1998: Thomas Leis; Roland Repp; Arndt Borkhardt; Markus Metzler; F Schläger; Jochen Harbott; Fritz H Lampert
A new fingerprint method for sequence analysis of chromosomal translocations at the genomic DNA level.
Leukemia 1998;12(5):758-63.
1997: Thomas Valerius; Bernhard Stockmeyer; Annemiek van Spriel; Robert F Graziano; IE van den Herik-Oudijk; Roland Repp; YM Deo; J Lund; Joachim R Kalden; Martin Gramatzki; Jan G J van de Winkel
FcalphaRI (CD89) as a novel trigger molecule for bispecific antibody therapy.
Blood 1997;90(11):4485-92.
1997: Heidi H van Ojik; Roland Repp; Gerard Groenewegen; Thomas Valerius; Jan G J van de Winkel
Clinical evaluation of the bispecific antibody MDX-H210 (anti-Fc gamma RI x anti-HER-2/neu) in combination with granulocyte-colony-stimulating factor (filgrastim) for treatment of advanced breast cancer.
Cancer immunology, immunotherapy : CII 1997;45(3-4):207-9.
1997: Thomas Valerius; D Würflein; Bernhard Stockmeyer; Roland Repp; Joachim R Kalden; Martin Gramatzki
Activated neutrophils as effector cells for bispecific antibodies.
Cancer immunology, immunotherapy : CII 1997;45(3-4):142-5.
1997: Thomas Valerius; D Elsässer; Roland Repp; Jan G J van de Winkel; Martin Gramatzki; Martin J Glennie
HLA class II antibodies recruit G-CSF activated neutrophils for treatment of B cell malignancies.
Leukemia & lymphoma 1997;26(3-4):261-9.
1997: Simone Stoll-Becker; Roland Repp; Dieter Glebe; Stephan Schaefer; Joachim Kreuder; Michael Kann; Fritz H Lampert; Wolfram H Gerlich
Transcription of hepatitis B virus in peripheral blood mononuclear cells from persistently infected patients.
Journal of virology 1997;71(7):5399-407.
1997: Astrid Rascu; Roland Repp; N A C Westerdaal; Joachim R Kalden; Jan G J van de Winkel
Clinical relevance of Fc gamma receptor polymorphisms.
Annals of the New York Academy of Sciences 1997;815():282-95.
1997: YM Deo; Robert F Graziano; Roland Repp; Jan G J van de Winkel
Clinical significance of IgG Fc receptors and Fc gamma R-directed immunotherapies.
Immunology today 1997;18(3):127-35.
1997: Bernhard Stockmeyer; Thomas Valerius; Roland Repp; IA Heijnen; H J Bühring; YM Deo; Joachim R Kalden; Martin Gramatzki; Jan G J van de Winkel
Preclinical studies with Fc(gamma)R bispecific antibodies and granulocyte colony-stimulating factor-primed neutrophils as effector cells against HER-2/neu overexpressing breast cancer.
Cancer research 1997;57(4):696-701.
1997: Arndt Borkhardt; Roland Repp; Oskar A Haas; Thomas Leis; Jochen Harbott; Joachim Kreuder; J Hammermann; T Henn; Fritz H Lampert
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23).
Oncogene 1997;14(2):195-202.
1996: Jörg Dötsch; Wieland Kiess; Jörg Hänze; Roland Repp; Dieter Lüdecke; Werner F Blum; Wolfgang Rascher
Gs alpha mutation at codon 201 in pituitary adenoma causing gigantism in a 6-year-old boy with McCune-Albright syndrome.
The Journal of clinical endocrinology and metabolism 1996;81(11):3839-42.
1996: S Schlieben; Arndt Borkhardt; I Reinisch; J Ritterbach; Johannes W G Janssen; Richard Ratei; Martin Schrappe; Roland Repp; Martin Zimmermann; Hartmut Kabisch; Gritta E Janka-Schaub; C R Bartram; Wolf-Dieter Ludwig; Hansjörg Riehm; Fritz H Lampert; Jochen Harbott
Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL). A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM-90 and CoALL-05-92.
Leukemia 1996;10(6):957-63.
1996: D Elsässer; Thomas Valerius; Roland Repp; G J Weiner; YM Deo; Joachim R Kalden; Jan G J van de Winkel; George T Stevenson; Martin J Glennie; Martin Gramatzki
HLA class II as potential target antigen on malignant B cells for therapy with bispecific antibodies in combination with granulocyte colony-stimulating factor.
Blood 1996;87(9):3803-12.
1996: Joachim Kreuder; Arndt Borkhardt; Roland Repp; A Pekrun; B Göttsche; U Gottschalk; Heinz Reichmann; W Schachenmayr; K Schlegel; Fritz H Lampert
Brief report: inherited metabolic myopathy and hemolysis due to a mutation in aldolase A.
The New England journal of medicine 1996;334(17):1100-4.
1996: Rainer M Bohle; S Brettreich; Roland Repp; Arndt Borkhardt; H Kosmehl; H M Altmannsberger
Single somatic ras gene point mutation in soft tissue malignant fibrous histiocytomas.
The American journal of pathology 1996;148(3):731-8.
1996: Hanns-Martin Lorenz; Christian Antoni; Thomas Valerius; Roland Repp; Mathias Grünke; N Schwerdtner; H Nüsslein; J Woody; Joachim R Kalden; Bernhard Manger
In vivo blockade of TNF-alpha by intravenous infusion of a chimeric monoclonal TNF-alpha antibody in patients with rheumatoid arthritis. Short term cellular and molecular effects.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(4):1646-53.
1996: Michael Eisenhut; W D Lehmann; Wolfgang Becker; T Behr; H Elser; W Strittmatter; A Steinsträsser; Richard P Baum; Thomas Valerius; Roland Repp; YM Deo
Bifunctional NHS-BAT ester for antibody conjugation and stable technetium-99m labeling: conjugation chemistry, immunoreactivity and kit formulation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(2):362-70.
1995: Roland Repp; Thomas Valerius; G Wieland; W Becker; H Steininger; YM Deo; G Helm; Martin Gramatzki; Jan G J van de Winkel; N Lang
G-CSF-stimulated PMN in immunotherapy of breast cancer with a bispecific antibody to Fc gamma RI and to HER-2/neu (MDX-210).
Journal of hematotherapy 1995;4(5):415-21.
1995: Arndt Borkhardt; O A Haas; W Strobl; Roland Repp; G Mann; H Gadner; F Lampert
A novel type of MLL/AF10 fusion transcript in a child with acute megakaryocytic leukemia (AML-M7)
Leukemia 1995;9(10):1796-7.
1995: A Borkhardt; S Brettreich; Arndt Borkhardt; Roland Repp; Jochen Harbott; Joachim Kreuder; Fritz H Lampert
Low frequency of RAS gene mutations and absence of mutations within the FLR exon of NF1 in patients with therapy-related leukemias.
Leukemia 1995;9(10):1790-1.
1995: Roland Repp; Arndt Borkhardt; R Gossen; Joachim Kreuder; J Hammermann; Fritz H Lampert
Construction of RNA standards for high-resolution automatic product analysis in quantitative competitive RT-PCR.
BioTechniques 1995;19(1):84, 86-8, 90.
1995: Arndt Borkhardt; M Mitteis; S Brettreich; S Schlieben; J Hammermann; Roland Repp; Joachim Kreuder; U Buchen; Fritz H Lampert
Rapid synthesis of hybrid RNA molecules associated with leukemia-specific chromosomal translocations.
Leukemia 1995;9(4):719-22.
1995: K Nishida; J Ritterbach; Roland Repp; Jochen Harbott; Fritz H Lampert
Characterization of chromosome 8 abnormalities by fluorescence in situ hybridization in childhood B-acute lymphoblastic leukemia/non-Hodgkin lymphoma.
Cancer genetics and cytogenetics 1995;79(1):8-14.
1995: Roland Repp; Arndt Borkhardt; E Haupt; Joachim Kreuder; S Brettreich; J Hammermann; K Nishida; Jochen Harbott; Fritz H Lampert
Detection of four different 11q23 chromosomal abnormalities by multiplex-PCR and fluorescence-based automatic DNA-fragment analysis.
Leukemia 1995;9(1):210-5.
1995: Renate Blütters-Sawatzki; Arndt Borkhardt; J Grathwohl; Roland Repp; I Rheinisch-Becker; Rainer M Bohle; Fritz H Lampert
Secondary acute myeloid leukemia with translocation (4;11) and MLL/AF4 rearrangement in a 15-year-old boy treated for common acute lymphoblastic leukemia 11 years earlier.
Annals of hematology 1995;70(1):31-5.
1994: Johannes W G Janssen; W D Ludwig; Arndt Borkhardt; U Spadinger; H Rieder; C Fonatsch; D K Hossfeld; Jochen Harbott; A S Schulz; Roland Repp
Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission.
Blood 1994;84(11):3835-42.
1994: T Maekawa; Roland Repp; T Abe; Arndt Borkhardt; F Lampert
Failure to detect BCR-ABL message in some Ph+ hematopoietic colonies: methodological aspects of the reverse transcriptase-polymerase chain reaction assay.
Blood 1994;84(9):3240-1.
1994: Wolfgang Becker; J Bair; T Behr; Roland Repp; H Streckenbach; H Beck; M Gramatzki; M J Winship; David M Goldenberg; F Wolf
Detection of soft-tissue infections and osteomyelitis using a technetium-99m-labeled anti-granulocyte monoclonal antibody fragment.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(9):1436-43.
1994: Arndt Borkhardt; Roland Repp; E Haupt; S Brettreich; U Buchen; R Gossen; Fritz H Lampert
Molecular analysis of MLL-1/AF4 recombination in infant acute lymphoblastic leukemia.
Leukemia 1994;8(4):549-53.
1993: Thomas Valerius; Roland Repp; T P de Wit; S Berthold; E Platzer; Joachim R Kalden; Martin Gramatzki; Jan G J van de Winkel
Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy.
Blood 1993;82(3):931-9.
1993: Arndt Borkhardt; Roland Repp; Jochen Harbott; M Lakomek; Johannes W G Janssen; S Schlieben; C R Bartram; Fritz H Lampert
BCR-ABL rearrangement in a child with acute myelogenous leukaemia without a Philadelphia chromosome.
British journal of haematology 1993;84(2):341-2.
1993: Roland Repp; S Rhiel; KH Heermann; Stephan Schaefer; C Keller; Peter Ndumbe; F Lampert; Wolfram H Gerlich
Genotyping by multiplex polymerase chain reaction for detection of endemic hepatitis B virus transmission.
Journal of clinical microbiology 1993;31(5):1095-102.
1993: Roland Repp; C Seuchter; B Breitbach; Fritz H Lampert; Wolfram H Gerlich
[Risk of hepatitis B virus transmission by highly viremic chronic carriers in schools].
Zentralblatt für Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine 1993;194(1-2):126-33.
1993: Arndt Borkhardt; Roland Repp; Jochen Harbott; Joachim Kreuder; Fritz H Lampert
Quantification of leukaemic cells based on heteroduplex formation of tal-1 gene sequences after PCR coamplification.
British journal of haematology 1993;83(1):39-44.
1993: Roland Repp; B von Hörsten; A Csecke; Joachim Kreuder; Arndt Borkhardt; W R Willems; Fritz H Lampert; Wolfram H Gerlich
Clinical and immunological aspects of hepatitis B virus infection in children receiving multidrug cancer chemotherapy.
Archives of virology. Supplementum 1993;8():103-11.
1992: J Grathwohl; Peter Ndumbe; R Leke; A Uy; Wolfram H Gerlich; Roland Repp
[Perinatal hepatitis B virus transmission].
Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft für Kinderheilkunde 1992;140(6):366-8.
1992: Arndt Borkhardt; Roland Repp; Jochen Harbott; C Keller; F Berner; J Ritterbach; Fritz H Lampert
Frequency and DNA sequence of tal-1 rearrangement in children with T-cell acute lymphoblastic leukemia.
Annals of hematology 1992;64(6):305-8.
1992: Roland Repp; C Keller; Arndt Borkhardt; A Csecke; Stephan Schaefer; Wolfram H Gerlich; F Lampert
Detection of a hepatitis B virus variant with a truncated X gene and enhancer II.
Archives of virology 1992;125(1-4):299-304.
1992: Roland Repp; A Mance; C Keller; S Rhiel; Wolfram H Gerlich; Fritz H Lampert
Detection of transcriptionally active hepatitis B virus DNA in peripheral mononuclear blood cells after infection during immunosuppressive chemotherapy using the polymerase chain reaction.
Archives of virology. Supplementum 1992;4():50-3.
1992: C Possehl; Roland Repp; KH Heermann; E Korec; A Uy; Wolfram H Gerlich
Absence of free core antigen in anti-HBc negative viremic hepatitis B carriers.
Archives of virology. Supplementum 1992;4():39-41.
1991: Roland Repp; Thomas Valerius; A Sendler; Martin Gramatzki; Heinrich Iro; Joachim R Kalden; E Platzer
Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human granulocyte colony-stimulating factor.
Blood 1991;78(4):885-9.
1990: Thomas Valerius; Roland Repp; Joachim R Kalden; E Platzer
Effects of IFN on human eosinophils in comparison with other cytokines. A novel class of eosinophil activators with delayed onset of action.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(9):2950-8.