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Kenneth Reuhl

Research Profile

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TOP 3
Rafal Goraczniak; Mark A Behlke; Suzie Chen; Eric S Ho; Christopher Jakubowski; Lumeng Jenny Yu; Stephanie Lacava; Kim A Lennox; Carlo Magaway; Neil R Patel; Kenneth R Reuhl; Stacey A Subbie; Brian A Wall; Nikolas H Zaphiros; Steven Zhao; Samuel I Gunderson
U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo.
Amanda K Smolarek; Jae Young So; Chung S Yang; Brenda Burgess; Yu-Kuo Chen; Ah-Ng Tony Kong; Mao-Jung Lee; Guangxun Li; Yong Lin; Kenneth R Reuhl; Weichung Joe Shih; Nanjoo Suh
Dietary administration of δ- and γ-tocopherol inhibits tumorigenesis in the animal model of estrogen receptor-positive, but not HER-2 breast cancer.
Guangxun Li; Anna B Liu; Kenneth R Reuhl; Hong Wang; Maarten C Bosland; Connie Cheung; Chung S Yang
Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.

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All Publications

2013: Rafal Goraczniak; Mark A Behlke; Suzie Chen; Eric S Ho; Christopher Jakubowski; Lumeng Jenny Yu; Stephanie Lacava; Kim A Lennox; Carlo Magaway; Neil R Patel; Kenneth R Reuhl; Stacey A Subbie; Brian A Wall; Nikolas H Zaphiros; Steven Zhao; Samuel I Gunderson
U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo.
Molecular therapy. Nucleic acids 2013;2():e92.
2012: Amanda K Smolarek; Jae Young So; Chung S Yang; Brenda Burgess; Yu-Kuo Chen; Ah-Ng Tony Kong; Mao-Jung Lee; Guangxun Li; Yong Lin; Kenneth R Reuhl; Weichung Joe Shih; Nanjoo Suh
Dietary administration of δ- and γ-tocopherol inhibits tumorigenesis in the animal model of estrogen receptor-positive, but not HER-2 breast cancer.
Cancer prevention research (Philadelphia, Pa.) 2012;5(11):1310-20.
2012: Guangxun Li; Anna B Liu; Kenneth R Reuhl; Hong Wang; Maarten C Bosland; Connie Cheung; Chung S Yang
Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.
Cancer prevention research (Philadelphia, Pa.) 2012;5(7):963-72.
2012: Min Zhang; Olga B Garbuzenko; Kenneth R Reuhl; Lorna Rodriguez-Rodriguez; Tamara Minko
Two-in-one: combined targeted chemo and gene therapy for tumor suppression and prevention of metastases.
Nanomedicine (London, England) 2012;7(2):185-97.
2011: Yu-Kuo Chen; Connie Cheung; Mao-Jung Lee; Anna Ba Liu; Yao-Ping Lu; Kenneth R Reuhl; Chung S Yang
Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice.
Journal of agricultural and food chemistry 2011;59(21):11862-71.
2011: Joan M Cranmer; Kenneth R Reuhl; Jason R Richardson; Leslie A Lang
Unifying mechanisms of neurological disorders--scientific, translational and clinical implications: overview and theme of the 26th International Neurotoxicology Conference.
Neurotoxicology 2011;32(5):499-501.
2010: Tiffany A Polanco; Catina Crismale-Gann; Kenneth R Reuhl; Dipak K Sarkar; Wendie S Cohick
Fetal alcohol exposure increases mammary tumor susceptibility and alters tumor phenotype in rats.
Alcoholism, clinical and experimental research 2010;34(11):1879-87.
2010: Avantika Barve; Tin Oo Khor; Kenneth R Reuhl; Bandaru Reddy; Harold L Newmark; Ah-Ng Tony Kong
Mixed tocotrienols inhibit prostate carcinogenesis in TRAMP mice.
Nutrition and cancer 2010;62(6):789-94.
2009: Avantika Barve; Tin Oo Khor; Sujit Nair; Kenneth R Reuhl; Nanjoo Suh; Bandaru Reddy; Harold Newmark; Ah-Ng Tony Kong
Gamma-tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice.
International journal of cancer. Journal international du cancer 2009;124(7):1693-9.
2009: Jing Hao; Bin Zhang; Ba Liu; Maojung Lee; Xingpei Hao; Kenneth R Reuhl; Xiaoxin Chen; Chung S Yang
Effect of alpha-tocopherol, N-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model.
International journal of cancer. Journal international du cancer 2009;124(6):1270-5.
2008: Mousumi Bose; Joshua D Lambert; Jihyeung Ju; Kenneth R Reuhl; Sue A Shapses; Chung S Yang
The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.
The Journal of nutrition 2008;138(9):1677-83.
2008: Carrie L Yochum; Peter Dowling; Kenneth R Reuhl; George C Wagner; Xue Ming
VPA-induced apoptosis and behavioral deficits in neonatal mice.
Brain research 2008;1203():126-32.
2008: Sonia Mesia-Vela; Rosa I Sanchez; Kathleen G Roberts; Kenneth R Reuhl; Allan H Conney; Frederick C Kauffman
Dietary clofibrate stimulates the formation and size of estradiol-induced breast tumors in female August-Copenhagen Irish (ACI) rats.
Toxicology 2008;246(1):63-72.
2007: George C Wagner; Kenneth R Reuhl; Xue Ming; Alycia K Halladay
Behavioral and neurochemical sensitization to amphetamine following early postnatal administration of methylmercury (MeHg).
Neurotoxicology 2007;28(1):59-66.
2006: Gang Lu; Jie Liao; Guang-Yu Yang; Kenneth R Reuhl; Xingpei Hao; Chung S Yang
Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine.
Cancer research 2006;66(23):11494-501.
2006: Kelly Burke; Yinghong Cheng; Baogang Li; Alex Petrov; Pushkar Joshi; Robert F Berman; Kenneth R Reuhl; Emanuel DiCicco-Bloom
Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E.
Neurotoxicology 2006;27(6):970-81.
2006: Liang-Ru Zhu; Paul E Thomas; Gang Lu; Kenneth R Reuhl; Guang-Yu Yang; Li-Dong Wang; Shou-Lin Wang; Chung S Yang; Xiao-Yang He; Jun-Yan Hong
CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(10):1672-6.
2006: George C Wagner; Kenneth R Reuhl; Michelle Cheh; Paulette McRae; Alycia K Halladay
A new neurobehavioral model of autism in mice: pre- and postnatal exposure to sodium valproate.
Journal of autism and developmental disorders 2006;36(6):779-93.
2006: Sonia Mesia-Vela; Rosa I Sanchez; Kenneth R Reuhl; Allan H Conney; Frederick C Kauffman
Phenobarbital treatment inhibits the formation of estradiol-dependent mammary tumors in the August-Copenhagen Irish rat.
The Journal of pharmacology and experimental therapeutics 2006;317(2):590-7.
2006: Ahmed Lasfar; Anita Lewis-Antes; Sergey V Smirnov; Shubha Anantha; Walid Abushahba; Bin Tian; Kenneth R Reuhl; Harold Dickensheets; Faruk Sheikh; Raymond P Donnelly; Elizabeth Raveche; Sergei V Kotenko
Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma.
Cancer research 2006;66(8):4468-77.
2006: Alycia K Halladay; D T Wilson; George C Wagner; Kenneth R Reuhl
Trimethyltin-induced alterations in behavior are linked to changes in PSA-NCAM expression.
Neurotoxicology 2006;27(2):137-46.
2005: D T Wilson; M A Polunas; Renping Zhou; Alycia K Halladay; Herbert E Lowndes; Kenneth R Reuhl
Methylmercury alters Eph and ephrin expression during neuronal differentiation of P19 embryonal carcinoma cells.
Neurotoxicology 2005;26(4):661-74.
2004: VK Turan; Rosa I Sanchez; J J Li; Sara Antonia Li; Kenneth R Reuhl; Paul E Thomas; Allan H Conney; M A Gallo; Frederick C Kauffman; Sonia Mesia-Vela
The effects of steroidal estrogens in ACI rat mammary carcinogenesis: 17beta-estradiol, 2-hydroxyestradiol, 4-hydroxyestradiol, 16alpha-hydroxyestradiol, and 4-hydroxyestrone.
The Journal of endocrinology 2004;183(1):91-9.
2004: Sonia Mesia-Vela; Rosa I Sanchez; Kenneth R Reuhl; Allan H Conney; Frederick C Kauffman
Dietary clofibrate inhibits induction of hepatic antioxidant enzymes by chronic estradiol in female ACI rats.
Toxicology 2004;200(2-3):103-11.
2004: Zhi-Yong Chen; Chunhua Sun; Kenneth R Reuhl; Andrew Bergemann; Mark Henkemeyer; Renping Zhou
Abnormal hippocampal axon bundling in EphB receptor mutant mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(10):2366-74.
2004: Xi Zheng; Richard L Chang; Xiao-Xing Cui; Gina E Avila; Sabrina Lee; Yao-Ping Lu; You-Rong Lou; Weichung Joe Shih; Yong Lin; Kenneth R Reuhl; Harold L Newmark; Arnold B Rabson; Allan H Conney
Inhibitory effect of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans-retinoic acid on the growth of LNCaP prostate tumors in immunodeficient mice.
Cancer research 2004;64(5):1811-20.
2003: Zhaoliang Hu; Xin Yue; Guanfang Shi; Yong Yue; David P Crockett; Jan Blair-Flynn; Kenneth R Reuhl; Lino Tessarollo; Renping Zhou
Corpus callosum deficiency in transgenic mice expressing a truncated ephrin-A receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(34):10963-70.
2003: Michael M Iba; Amijoy Storch; Anima Ghosal; Susan Bennett; Kenneth R Reuhl; Herbert E Lowndes
Constitutive and inducible levels of CYP1A1 and CYP1A2 in rat cerebral cortex and cerebellum.
Archives of toxicology 2003;77(10):547-54.
2003: Mei Zhang; Sherry Thurig; Maria Tsirigotis; Paul K Y Wong; Kenneth R Reuhl; Douglas A Gray
Effects of mutant ubiquitin on ts1 retrovirus-mediated neuropathology.
Journal of virology 2003;77(13):7193-201.
2003: Pam Pollock; Karine A Cohen-Solal; Raman Sood; Jin Namkoong; Jeffrey J Martino; Aruna Koganti; Hua Zhu; Christiane Robbins; Izabela Makalowska; Seung-Shick Shin; Yari Marin; Kathleen G Roberts; Laura M Yudt; Amy Chen; Jun Cheng; Arturo Incao; Heather Pinkett; Christopher L Graham; Karen Dunn; Steven M Crespo-Carbone; Kerine R Mackason; Kevin B Ryan; Daniel Sinsimer; James S Goydos; Kenneth R Reuhl; Michael Eckhaus; Paul S Meltzer; William J Pavan; Jeffrey M. Trent; Suzie Chen
Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.
Nature genetics 2003;34(1):108-12.
2002: Nobuya Ishibashi; Olga Prokopenko; Miriam Weisbrot-Lefkowitz; Kenneth R Reuhl; Oleg Mirochnitchenko
Glutathione peroxidase inhibits cell death and glial activation following experimental stroke.
Brain research. Molecular brain research 2002;109(1-2):34-44.
2002: Walter C Prozialeck; Gerald B Grunwald; P Markus Dey; Kenneth R Reuhl; Alan R Parrish
Cadherins and NCAM as potential targets in metal toxicity.
Toxicology and applied pharmacology 2002;182(3):255-65.
2002: Karine A Cohen-Solal; Steven M Crespo-Carbone; Jin Namkoong; Kerine R Mackason; Kathleen G Roberts; Kenneth R Reuhl; Suzie Chen
Progressive appearance of pigmentation in amelanotic melanoma lesions.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2002;15(4):282-9.
2002: Ronald L Melnick; George W Lucier; Mary Wolfe; Roxanne Hall; George Stancel; Gail S Prins; Michael Gallo; Kenneth R Reuhl; Shuk-Mei Ho; Terry R Brown; John Moore; Julian Leakey; Joseph Haseman; Michael Kohn
Summary of the National Toxicology Program's report of the endocrine disruptors low-dose peer review.
Environmental health perspectives 2002;110(4):427-31.
2002: Nobuya Ishibashi; Olga Prokopenko; Kenneth R Reuhl; Oleg Mirochnitchenko
Inflammatory response and glutathione peroxidase in a model of stroke.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1926-33.
2001: S J Pyle; Kathleen G Roberts; Kenneth R Reuhl
Delayed expression of the NFH subunit in differentiating P19 cells.
Brain research. Developmental brain research 2001;132(1):103-6.
2001: Karine A Cohen-Solal; Kenneth R Reuhl; K B Ryan; Kathleen G Roberts; Suzie Chen
Development of cutaneous amelanotic melanoma in the absence of a functional tyrosinase.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2001;14(6):466-74.
2000: R T Angner; R M Kelly; R G Wiley; T J Walsh; Kenneth R Reuhl
Preferential destruction of cerebellar Purkinje cells by OX7-saporin.
Neurotoxicology 2000;21(3):395-403.
2000: H Zhu; Kenneth R Reuhl; Rosanne L Botha; K Ryan; J Wei; Suzie Chen
Development of early melanocytic lesions in transgenic mice predisposed to melanoma.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2000;13(3):158-64.
2000: P M Dey; J Burger; M Gochfeld; Kenneth R Reuhl
Developmental lead exposure disturbs expression of synaptic neural cell adhesion molecules in herring gull brains.
Toxicology 2000;146(2-3):137-47.
2000: Martin A Philbert; Melvin Billingsley; Kenneth R Reuhl
Mechanisms of injury in the central nervous system.
Toxicologic pathology 2000;28(1):43-53.
1999: Nobuya Ishibashi; Miriam Weisbrot-Lefkowitz; Kenneth R Reuhl; Masayori Inouye; Oleg Mirochnitchenko
Modulation of chemokine expression during ischemia/reperfusion in transgenic mice overproducing human glutathione peroxidases.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5666-77.
1999: P M Dey; M Gochfeld; Kenneth R Reuhl
Developmental methylmercury administration alters cerebellar PSA-NCAM expression and Golgi sialyltransferase activity.
Brain research 1999;845(2):139-51.
1999: Oleg Mirochnitchenko; Miriam Weisbrot-Lefkowitz; Kenneth R Reuhl; Li Chen; C Yang; Masayori Inouye
Acetaminophen toxicity. Opposite effects of two forms of glutathione peroxidase.
The Journal of biological chemistry 1999;274(15):10349-55.
1998: H Zhu; Kenneth R Reuhl; X Zhang; Rosanne L Botha; K Ryan; J Wei; S Chen
Development of heritable melanoma in transgenic mice.
The Journal of investigative dermatology 1998;110(3):247-52.
1998: Miriam Weisbrot-Lefkowitz; Kenneth R Reuhl; B Perry; P H Chan; Masayori Inouye; Oleg Mirochnitchenko
Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage.
Brain research. Molecular brain research 1998;53(1-2):333-8.
1997: S R Goldstein; Guang-Yu Yang; SK Curtis; Kenneth R Reuhl; B C Liu; S S Mirvish; Harold L Newmark; Chung S Yang
Development of esophageal metaplasia and adenocarcinoma in a rat surgical model without the use of a carcinogen.
Carcinogenesis 1997;18(11):2265-70.
1997: Y Li; E J Wang; L Chen; A P Stein; Kenneth R Reuhl; Chung S Yang
Effects of phenethyl isothiocyanate on acetaminophen metabolism and hepatotoxicity in mice.
Toxicology and applied pharmacology 1997;144(2):306-14.
1997: Ronald D Graff; M M Falconer; D L Brown; Kenneth R Reuhl
Altered sensitivity of posttranslationally modified microtubules to methylmercury in differentiating embryonal carcinoma-derived neurons.
Toxicology and applied pharmacology 1997;144(2):215-24.
1997: P M Dey; M A Polunas; Martin A Philbert; Kenneth R Reuhl
Altered expression of polysialylated NCAM in mouse hippocampus following trimethyltin administration.
Neurotoxicology 1997;18(3):633-43.
1996: M C Lin; E J Wang; C Patten; Mao-Jung Lee; F Xiao; Kenneth R Reuhl; Chung S Yang
Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice.
Journal of biochemical toxicology 1996;11(1):11-20.
1996: E J Wang; Y Li; M Lin; L Chen; A P Stein; Kenneth R Reuhl; Chung S Yang
Protective effects of garlic and related organosulfur compounds on acetaminophen-induced hepatotoxicity in mice.
Toxicology and applied pharmacology 1996;136(1):146-54.
1995: C M Beiswanger; M H Diegmann; Raymond F Novak; Martin A Philbert; T L Graessle; Kenneth R Reuhl; Herbert E Lowndes
Developmental changes in the cellular distribution of glutathione and glutathione S-transferases in the murine nervous system.
Neurotoxicology 1995;16(3):425-40.
1995: Martin A Philbert; C M Beiswanger; M M Manson; J A Green; Raymond F Novak; T Primiano; Kenneth R Reuhl; Herbert E Lowndes
Glutathione S-transferases and gamma-glutamyl transpeptidase in the rat nervous systems: a basis for differential susceptibility to neurotoxicants.
Neurotoxicology 1995;16(2):349-62.
1994: P M Dey; Ronald D Graff; L A Lagunowich; Kenneth R Reuhl
Selective loss of the 180-kDa form of the neural cell adhesion molecule in hippocampus and cerebellum of the adult mouse following trimethyltin administration.
Toxicology and applied pharmacology 1994;126(1):69-74.
1994: Herbert E Lowndes; C M Beiswanger; Martin A Philbert; Kenneth R Reuhl
Substrates for neural metabolism of xenobiotics in adult and developing brain.
Neurotoxicology 1994;15(1):61-73.
1994: Kenneth R Reuhl; L A Lagunowich; D L Brown
Cytoskeleton and cell adhesion molecules: critical targets of toxic agents.
Neurotoxicology 1994;15(1):133-45.
1994: L A Lagunowich; A P Stein; Kenneth R Reuhl
N-cadherin in normal and abnormal brain development.
Neurotoxicology 1994;15(1):123-32.
1994: M M Falconer; A Vaillant; Kenneth R Reuhl; N Laferrière; D L Brown
The molecular basis of microtubule stability in neurons.
Neurotoxicology 1994;15(1):109-22.
1993: Jennifer Hu; Mao-Jung Lee; M Vapiwala; Kenneth R Reuhl; P E Thomas; Chung S Yang
Sex-related differences in mouse renal metabolism and toxicity of acetaminophen.
Toxicology and applied pharmacology 1993;122(1):16-26.
1993: Ronald D Graff; Martin A Philbert; Herbert E Lowndes; Kenneth R Reuhl
The effect of glutathione depletion on methyl mercury-induced microtubule disassembly in cultured embryonal carcinoma cells.
Toxicology and applied pharmacology 1993;120(1):20-8.
1993: C M Beiswanger; T L Roscoe-Graessle; N Zerbe; Kenneth R Reuhl; Herbert E Lowndes
3-Acetylpyridine-induced degeneration in the dorsal root ganglia: involvement of small diameter neurons and influence of axotomy.
Neuropathology and applied neurobiology 1993;19(2):164-72.
1993: Kenneth R Reuhl; M Vapiwala; M T Ryzlak; C P Schaffner
Comparative neurotoxicities of amphotericin B and its mono-methyl ester derivative in rats.
Antimicrobial agents and chemotherapy 1993;37(3):419-28.
1993: C M Beiswanger; R D Mandella; T R Graessle; Kenneth R Reuhl; Herbert E Lowndes
Synergistic neurotoxic effects of styrene oxide and acrylamide: glutathione-independent necrosis of cerebellar granule cells.
Toxicology and applied pharmacology 1993;118(2):233-44.
1992: D A Delio; Kenneth R Reuhl; Herbert E Lowndes
Ectopic impulse generation in dorsal root ganglion neurons during methylmercury intoxication: an electrophysiological and morphological study.
Neurotoxicology 1992;13(3):527-39.
1991: Martin A Philbert; C M Beiswanger; D K Waters; Kenneth R Reuhl; Herbert E Lowndes
Cellular and regional distribution of reduced glutathione in the nervous system of the rat: histochemical localization by mercury orange and o-phthaldialdehyde-induced histofluorescence.
Toxicology and applied pharmacology 1991;107(2):215-27.
1991: Kenneth R Reuhl
Delayed expression of neurotoxicity: the problem of silent damage.
Neurotoxicology 1991;12(3):341-6.
1990: R L DeGrandchamp; Kenneth R Reuhl; Herbert E Lowndes
Synaptic terminal degeneration and remodeling at the rat neuromuscular junction resulting from a single exposure to acrylamide.
Toxicology and applied pharmacology 1990;105(3):422-33.