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Giuliana Biagi

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Giorgi Irene; Leonardi Michele; Pietra Daniele; Biagi Giuliana; Borghini Alice; Massarelli Ilaria; Ciampi Osele; Bianucci Anna Maria
Synthesis, biological assays and QSAR studies of N-(9-benzyl-2-phenyl-8-azapurin-6-yl)-amides as ligands for A1 adenosine receptors.
Giorgi Irene; Biagi Giuliana; Bianucci Anna Maria; Borghini Alice; Livi Oreste; Leonardi Michele; Pietra Daniele; Calderone Vincenzo; Martelli Alma
N6-1,3-diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors.
Massarelli Ilaria; Coi Alessio; Pietra Daniele; Nofal Fatena Ahmad; Biagi Giuliana; Giorgi Irene; Leonardi Michele; Fiamingo Francesca; Bianucci Anna Maria
QSAR study on a novel series of 8-azaadenine analogues proposed as A1 adenosine receptor antagonists.

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2009: Giorgi Irene; Leonardi Michele; Pietra Daniele; Biagi Giuliana; Borghini Alice; Massarelli Ilaria; Ciampi Osele; Bianucci Anna Maria
Synthesis, biological assays and QSAR studies of N-(9-benzyl-2-phenyl-8-azapurin-6-yl)-amides as ligands for A1 adenosine receptors.
Bioorganic & medicinal chemistry 2009;17(5):1817-30.
2008: Giorgi Irene; Biagi Giuliana; Bianucci Anna Maria; Borghini Alice; Livi Oreste; Leonardi Michele; Pietra Daniele; Calderone Vincenzo; Martelli Alma
N6-1,3-diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors.
European journal of medicinal chemistry 2008;43(8):1639-47.
2008: Massarelli Ilaria; Coi Alessio; Pietra Daniele; Nofal Fatena Ahmad; Biagi Giuliana; Giorgi Irene; Leonardi Michele; Fiamingo Francesca; Bianucci Anna Maria
QSAR study on a novel series of 8-azaadenine analogues proposed as A1 adenosine receptor antagonists.
European journal of medicinal chemistry 2008;43(1):114-21.
2007: Giorgi Irene; Biagi Giuliana; Livi Oreste; Leonardi Michele; Scartoni Valerio; Pietra Daniele
Synthesis of new 2-phenyladenines and 2-phenylpteridines and biological evaluation as adenosine receptor ligands.
Archiv der Pharmazie 2007;340(2):81-7.
2007: Giorgi Irene; Bianucci Anna Maria; Biagi Giuliana; Livi Oreste; Scartoni Valerio; Leonardi Michele; Pietra Daniele; Coi Alessio; Massarelli Ilaria; Nofal Fatena Ahmad; Fiamingo Francesca Lidia; Anastasi Paola; Giannini Giuliano
Synthesis, biological activity and molecular modelling of new trisubstituted 8-azaadenines with high affinity for A1 adenosine receptors.
European journal of medicinal chemistry 2007;42(1):1-9.
2005: Biagi Giuliana; Bianucci Anna Maria; Coi Alessio; Costa Barbara; Fabbrini Laura; Giorgi Irene; Livi Oreste; Micco Iolanda; Pacchini Federica; Santini Edoardo; Leonardi Michele; Nofal Fatena Ahmad; Salerni Oreste LeRoy; Scartoni Valerio
2,9-disubstituted-N6-(arylcarbamoyl)-8-azaadenines as new selective A3 adenosine receptor antagonists: synthesis, biochemical and molecular modelling studies.
Bioorganic & medicinal chemistry 2005;13(15):4679-93.
2004: Biagi Giuliana; Giorgi Irene; Livi Oreste; Nardi Antonio; Calderone Vincenzo; Martelli Alma; Martinotti Enrica; LeRoy Salerni Oreste
Synthesis and biological activity of novel substituted benzanilides as potassium channel activators. V.
European journal of medicinal chemistry 2004;39(6):491-8.
2004: Biagi Giuliana; Calderone Vincenzo; Giorgi Irene; Livi Oreste; Martinotti Enrica; Martelli Alma; Nardi Antonio
1,5-Diarylsubstituted 1,2,3-triazoles as potassium channel activators. VI.
Farmaco (Società chimica italiana : 1989) 2004;59(5):397-404.
2003: Biagi Giuliana; Giorgi Irene; Livi Oreste; Nardi Antonio; Pacchini Federica; Scartoni Valerio; Lucacchini Antonio
N6-cycloalkyl-2-phenyl-3-deaza-8-azaadenines: a new class of A1 adenosine receptor ligands. A comparison with the corresponding adenines and 8-azaadenines.
European journal of medicinal chemistry 2003;38(11-12):983-90.
2003: Biagi Giuliana; Giorgi Irene; Leonardi Michele; Livi Oreste; Pacchini Federica; Scartoni Valerio; Costa Barbara; Lucacchini Antonio
New N6- or N(9)-hydroxyalkyl substituted 8-azaadenines or adenines as effective A1 adenosine receptor ligands.
European journal of medicinal chemistry 2003;38(9):801-10.
2003: Biagi Giuliana; Giorgi Irene; Livi Oreste; Scartoni Valerio; Barili Pier Luigi
Characterization and preliminary use of 1-, 2- and 3-methyl-5-phenyl-7-chloro-1,2,3-triazolo[4,5-d]pyrimidine as reaction intermediates.
Farmaco (Società chimica italiana : 1989) 2003;58(8):551-6.
2002: Biagi Giuliana; Giorgi Irene; Livi Oreste; Scartoni Valerio; Betti Laura; Giannaccini Gino; Trincavelli Maria Letizia
New 1,2,3-triazolo[1,5-a]quinoxalines: synthesis and binding to benzodiazepine and adenosine receptors. II.
European journal of medicinal chemistry 2002;37(7):565-71.
2002: Biagi Giuliana; Giorgi Irene; Livi Oreste; Pacchini Federica; Rum Pietro; Scartoni Valerio; Costa Barbara; Mazzoni Maria Rosa; Giusti Laura
Erythro- and threo-2-hydroxynonyl substituted 2-phenyladenines and 2-phenyl-8-azaadenines: ligands for A1 adenosine receptors and adenosine deaminase.
Farmaco (Società chimica italiana : 1989) 2002;57(3):221-33.
2001: Biagi G; Giorgi I; Pacchini F; Livi O; Scartoni V
New 2-(2'-phenyl-9'-benzyl-8'-azapurin-6'-ylamino)-carboxylic acid methylesters as ligands for A1 adenosine receptors.
Farmaco (Società chimica italiana : 1989) 2001;56(12):929-31.
2001: Biagi G; Calderone V; Giorgi I; Livi O; Scartoni V; Baragatti B; Martinotti E
Some structural changes on triazolyl-benzotriazoles and triazolyl-benzimidazolones as potential potassium channel activators. III.
Farmaco (Società chimica italiana : 1989) 2001;56(11):841-9.
2001: Biagi G; Giorgi I; Livi O; Scartoni V; Barili P L; Calderone V; Martinotti E
New 5-substituted-1-(2-hydroxybenzoyl)-benzotriazoles, potassium channel activators. IV.
Farmaco (Società chimica italiana : 1989) 2001;56(11):827-34.
2001: Biagi G; Giorgi I; Pacchini F; Livi O; Scartoni V
2-Alkyloxyalkylthiohypoxanthines as new potent inhibitors of xanthine oxidase.
Farmaco (Società chimica italiana : 1989) 2001;56(11):809-13.
2000: Baragatti B; Biagi G; Calderone V; Giorgi I; Livi O; Martinotti E; Scartoni V
Triazolyl-benzimidazolones and triazolyl-benzotriazoles: new potential potassium channel activators. II.
European journal of medicinal chemistry 2000;35(10):949-55.
2000: Biagi G; Calderone V; Giorgi I; Livi O; Scartoni V; Baragatti B; Martinotti E
5-(4'-Substituted-2'-nitroanilino)-1,2,3-triazoles as new potential potassium channel activators. I.
European journal of medicinal chemistry 2000;35(7-8):715-20.
2000: Bertelli L; Biagi G; Giorgi I; Livi O; Manera C; Scartoni V; Lucacchini A; Giannaccini G; Barili P L
Substituted 1,2,3-triazolo[1,5-a]quinazolines: synthesis and binding to benzodiazepine and adenosine receptors.
European journal of medicinal chemistry 2000;35(3):333-41.
1998: Biagi G; Giorgi I; Livi O; Scartoni V; Martinotti E; Calderone V
New 1,2,3-triazole derivatives (ureas, amides, urethanes) with a potential biological interest.
Bollettino chimico farmaceutico 1998;137(9):350-6.
1998: Bianucci A M; Bigi M U; Biagi G; Giorgi I; Livi O; Scartoni V
A 3D model of the human A1 adenosine receptor. An evaluation of the binding free-energy with ligands.
Drug design and discovery 1998;15(3):149-56.
1998: Bertelli L; Biagi G; Giorgi I; Livi O; Manera C; Scartoni V; Martini C; Giannaccini G; Trincavelli L; Barili P L
1,2,3-Triazolo[1,5-a][1,4]- and 1,2,3-triazolo[1,5-a]-[1,5]benzodiazepine derivatives: synthesis and benzodiazepine receptor binding.
Farmaco (Società chimica italiana : 1989) 1998;53(4):305-11.
1998: Betti L; Biagi G; Giannaccini G; Giorgi I; Livi O; Lucacchini A; Manera C; Scartoni V
Novel 3-aralkyl-7-(amino-substituted)-1,2,3-triazolo[4,5-d]pyrimidines with high affinity toward A1 adenosine receptors.
Journal of medicinal chemistry 1998;41(5):668-73.
1997: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A
Synthesis of 4,6-disubstituted- and 4,5,6-trisubstituted-2-phenyl-pyrimidines and their affinity towards A1 adenosine receptors.
Farmaco (Società chimica italiana : 1989) 1997;52(1):61-5.
1996: Biagi G; Giorgi I; Livi O; Scartoni V; Catalani R; Gervasi G
New chiral inhibitors of induced platelet aggregation: the enantiomeric specificity of (R)- and (S)-methyl and ethyl esters of 1-(4-[(1-hydroxycarbonyl)-ethoxy]-benzyl)-1H-1,2,3-triazole as a tool for determining their biological target.
Farmaco (Società chimica italiana : 1989) 1996;51(12):761-6.
1996: Biagi G; Giorgi I; Livi O; Manera C; Scartoni V; Lucacchini A; Senatore G
1,2,3-Triazolo [4,5-d] pyridazines--V. Preparation and adenosine receptor binding of new 4-amino derivatives.
Farmaco (Società chimica italiana : 1989) 1996;51(8-9):601-8.
1996: Biagi G; Giorgi I; Livi O; Scartoni V
N(9)-Substituted 2-phenyl-N(6)-benzyl-8-azaadenines: A1 adenosine receptor affinity. A comparison with the corresponding N(6)-substituted 2-phenyl-N(9)-benzyl-8-azaadenines.
Farmaco (Società chimica italiana : 1989) 1996;51(6):395-9.
1996: Biagi G; Costantini A; Costantino L; Giorgi I; Livi O; Pecorari P; Rinaldi M; Scartoni V
Synthesis and biological evaluation of new imidazole, pyrimidine, and purine derivatives and analogs as inhibitors of xanthine oxidase.
Journal of medicinal chemistry 1996;39(13):2529-35.
1996: Biagi G; Giorgi I; Livi O; Scartoni V; Velo S; Lucacchini A; Senatore G; De Santis B; Martinelli A
1,2,3-triazolo[1.5-a]quinazolines: synthesis, benzodiazepine receptor binding and theoretical calculations.
Farmaco (Società chimica italiana : 1989) 1996;51(2):131-6.
1995: Biagi G; Giorgi I; Livi O; Scartoni V; Breschi C; Martini C; Scatizzi R
N(6) or N(9) substituted 2-phenyl-8-azaadenines: affinity for A1 adenosine receptors. VII.
Farmaco (Società chimica italiana : 1989) 1995;50(10):659-67.
1995: Biagi G; Giorgi I; Livi O; Scartoni V; Tonetti I; Costantino L
Xanthine oxidase (XO). 4(5)-aminosubstituted-5(4)-carboxyamido-1H-1,2, 3-triazoles: a new class of monocyclic triazole inhibitors.
Farmaco (Società chimica italiana : 1989) 1995;50(4):257-64.
1995: Biagi G; Giorgi I; Livi O; Scartoni V; Velo S; Martini C; Senatore G; Barili P L
1,2,3-triazole[4,5-d]pyridazines--IV. Preparation and adenosine receptor binding of new 4 and/or 7 aminoderivatives.
Farmaco (Società chimica italiana : 1989) 1995;50(2):99-105.
1995: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Martini C; Tacchi P
Synthesis of new N(6)-substituted 2-phenyl-8-azaadenosines. Their affinity for adenosine A1 and A2 receptors. A comparison with the corresponding 2-phenyl-9-benzyl-8-azaadenines. VI.
Farmaco (Società chimica italiana : 1989) 1995;50(1):13-9.
1994: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Senatore G; Barili P L
1,2,3-triazole[4,5-d]pyridazines. III--Synthesis of new 4-amino derivatives and their affinity toward adenosine receptors.
Farmaco (Società chimica italiana : 1989) 1994;49(5):357-62.
1994: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Martini C; Tacchi P
N(6)-substituted 2-phenyl-9-benzyl-8-azaadenines. Affinity for adenosine A1 and A2 receptors. A comparison with 2-N-butyl analogous derivatives. V.
Farmaco (Società chimica italiana : 1989) 1994;49(3):187-91.
1994: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Martini C; Tacchi P
N(6)-substituted 2-N-butyl-9-benzyl-8-azaadenines. Affinity for adenosine A1 and A2 receptors. IV.
Farmaco (Società chimica italiana : 1989) 1994;49(3):183-6.
1994: Biagi G; Giorgi I; Livi O; Scartoni V; Martini C; Tacchi P; Merlino S; Pasero M
1,2,3-Triazole[4,5-d]pyridazines--II. New derivatives tested on adenosine receptors.
Farmaco (Società chimica italiana : 1989) 1994;49(3):175-81.
1994: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Martini C; Tacchi P
2-Aryl-8-azaadenosines: structure-activity relationships in the binding with A1 and A2 receptors. A comparison with the corresponding 9-benzyl-8-azaadenines. III.
Farmaco (Società chimica italiana : 1989) 1994;49(2):93-6.
1993: Biagi G; Giorgi I; Livi O; Lucacchini A; Martini C; Scartoni V
Studies on specific inhibition of benzodiazepine receptor binding by some C-benzoyl-1,2,3-triazole derivatives.
Journal of pharmaceutical sciences 1993;82(9):893-6.
1993: Biagi G; Ferretti M; Giorgi I; Livi O; Scartoni V; Lucacchini A
1,2,3-Triazole[4,5-d]pyridazines--I. Analogues of prostaglandin synthesis inhibitors.
Farmaco (Società chimica italiana : 1989) 1993;48(8):1159-65.
1993: Biagi G; Giorgi I; Livi O; Scartoni V; Tonetti I; Lucacchini A
Xanthine oxidase (XO): relative configuration of complexes formed by the enzyme, 2- or 8-n-alkyl-hypoxanthines and 2-n-alkyl-8-azahypoxanthines. XII.
Farmaco (Società chimica italiana : 1989) 1993;48(3):357-74.
1992: Biagi G; Livi O; Lucacchini A; Martini C; Scartoni V
Specific inhibition of binding to benzodiazepine receptors by 1,2,3-triazole derivatives.
Journal of pharmaceutical sciences 1992;81(6):543-5.
1992: Biagi G; Giorgi I; Livi O; Scartoni V
Synthesis and ADA inhibitory activity of new 2-aryl-8-azaadenosines. VIII.
Farmaco (Società chimica italiana : 1989) 1992;47(5):537-50.
1992: Biagi G; Dell'Omodarme G; Ferretti M; Giorgi I; Livi O; Scartoni V
Structure-activity studies on a 1,2,3-triazole derivative, a potent in vitro inhibitor of prostaglandin synthesis: the role of the heterocyclic ring.
Farmaco (Società chimica italiana : 1989) 1992;47(3):335-44.
1992: Biagi G; Dell'Omodarme G; Giorgi I; Livi O; Scartoni V; Di Bussolo V
An 1,2,3-triazole derivative bioisoster of a potent in vitro prostaglandin synthesis inhibitor: preparation and biological activity.
Farmaco (Società chimica italiana : 1989) 1992;47(1):91-8.
1990: Biagi G; Dell'Omodarme G; Ferretti M; Giorgi I; Livi O; Scartoni V; Tiscione E
Studies on 1,2,3-triazole derivatives as in vitro inhibitors of prostaglandin synthesis.
Farmaco (Società chimica italiana : 1989) 1990;45(11):1181-92.
1990: Biagi G; Dell'Omodarme G; Giorgi I; Livi O; Scartoni V
In vitro inhibitors of prostaglandin synthesis: (p-thiosubstituted)-benzyl nitrogen heterocycles.
Farmaco (Società chimica italiana : 1989) 1990;45(9):989-99.
1990: Biagi G; Livi O; Ramacciotti G L; Scartoni V; Bazzichi L; Mazzoni M R; Lucacchini A
Superoxide dismutase-like activity of 1,2,3-triazole derivatives.
Farmaco (Società chimica italiana : 1989) 1990;45(1):49-57.
1989: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A
Xanthine oxidase inhibition: effect of an N-alkyl substituent on C-2 of the nucleus of 8-azahypoxanthine.
Farmaco (Società chimica italiana : 1989) 1989;44(9):843-9.
1989: Andreini F; Biagi G; Giorgi I; Livi O; Scartoni V
Modification of the 1,2,3-triazole ring present in an effective in vitro inhibitor of the prostaglandin synthesis.
Farmaco (Società chimica italiana : 1989) 1989;44(9):831-41.
1988: Martini C; Marrucci W; Lucacchini A; Biagi G; Livi O
Specific inhibition of benzodiazepine receptor binding by some 1,2,3-triazole derivatives.
Journal of pharmaceutical sciences 1988;77(11):977-80.
1988: Biagi G; Livi O; Scartoni V; Verugi E
1,2,3-Triazoles: structural changes on two effective inhibitors of the prostaglandin synthesis in vitro.
Il Farmaco; edizione scientifica 1988;43(7-8):597-611.
1987: Biagi G; Livi O; Scartoni V
Studies on 1,2,3-triazole derivatives as potential inhibitors of the cyclo-oxygenase.
Il Farmaco; edizione scientifica 1987;42(4):285-97.
1986: Biagi G; Livi O; Scartoni V; Lucacchini A; Mazzoni M R
N-benzyl-4-phenyl-1,2,3-triazole derivatives as in vitro inhibitors of the prostaglandin synthesis.
Il Farmaco; edizione scientifica 1986;41(8):597-610.
1986: Biagi G; Ferretti M; Livi O; Scartoni V; Lucacchini A; Mazzoni M
4-Benzoyl- and 4-benzyl-1,2,3-triazol-N-acetic acids, in vitro inhibitors of the prostaglandin synthesis.
Il Farmaco; edizione scientifica 1986;41(5):388-400.
1985: Biagi G; Livi O; Da Settimo A; Lucacchini A; Mazzoni M R; Barili P L
4-(4-Phenylsubstituted)-1,2,3-triazolacetic acid derivatives in vitro inhibitors of prostaglandin synthesis.
Il Farmaco; edizione scientifica 1985;40(2):73-85.
1983: Da Settimo A; Livi O; Biagi G; Lucacchini A; Caselli S
1,2,3-Triazole derivatives of salicylic acid.
Il Farmaco; edizione scientifica 1983;38(10):725-37.
1982: Da Settimo A; Livi O; Biagi G; Primofiore G; Masoni G
1,2,3-Triazole derivatives of aryloxyalanoic acids.
Il Farmaco; edizione scientifica 1982;37(11):728-39.
1982: Da Settimo A; Primofiore G; Biagi G; Martini C; Zoppi M; Lucacchini A
Specific inhibition of benzodiazepine receptor binding by some 6H-indolo[2,3-b] [1,8]naphthyridines and 11H-indolo [3,2-c] [1,8]naphthyridines.
Il Farmaco; edizione scientifica 1982;37(11):740-6.
1982: Lucacchini A; Bazzichi L; Biagi G; Livi O; Segnini D
Effects of 6,9-disubstituted 8-azapurines on adenosine deaminase, guanine deaminase and xanthine oxidase.
The Italian journal of biochemistry 1982;31(3):153-62.
1980: Da Settimo A; Livi O; Ferrarini P L; Biagi G
Synthesis and pharmacological activity of three new 9-aryl-8-azaadenine derivatives.
Il Farmaco; edizione scientifica 1980;35(4):308-32.

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