FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

John Biaglow

Research Profile

Chemicals & Drugs

Physiology

Anatomy

Phenomena

Oxidation-Reduction

Living Beings

Concepts & Ideas

Kinetics

Co-author Network

Publications

TOP 3
Iraimoudi S Ayene; John E Biaglow; Alexander V Kachur; Thomas D Stamato; Cameron J Koch
Mutation in G6PD gene leads to loss of cellular control of protein glutathionylation: mechanism and implication.
Stephen W Tuttle; Amit Maity; Patricia R Oprysko; Alexander V Kachur; Iraimoudi S Ayene; John E Biaglow; Cameron J Koch
Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration: implications for the mechanism of HIF-1alpha stabilization under moderate hypoxia.
John E Biaglow; Iraimoudi S Ayene; Stephen W Tuttle; Cameron J Koch; Jeremiah Donahue; John J Mieyal
Role of vicinal protein thiols in radiation and cytotoxic responses.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of John Biaglow (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2008: Iraimoudi S Ayene; John E Biaglow; Alexander V Kachur; Thomas D Stamato; Cameron J Koch
Mutation in G6PD gene leads to loss of cellular control of protein glutathionylation: mechanism and implication.
Journal of cellular biochemistry 2008;103(1):123-35.
2007: Stephen W Tuttle; Amit Maity; Patricia R Oprysko; Alexander V Kachur; Iraimoudi S Ayene; John E Biaglow; Cameron J Koch
Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration: implications for the mechanism of HIF-1alpha stabilization under moderate hypoxia.
The Journal of biological chemistry 2007;282(51):36790-6.
2006: John E Biaglow; Iraimoudi S Ayene; Stephen W Tuttle; Cameron J Koch; Jeremiah Donahue; John J Mieyal
Role of vicinal protein thiols in radiation and cytotoxic responses.
Radiation research 2006;165(3):307-17.
2005: Darren Magda; Philip Lecane; Richard A Miller; Cheryl Lepp; Dale Miles; Mimi Mesfin; John E Biaglow; Vincent V Ho; Danny Chawannakul; Shailender Nagpal; Mazen W Karaman; Joseph G Hacia
Motexafin gadolinium disrupts zinc metabolism in human cancer cell lines.
Cancer research 2005;65(9):3837-45.
2005: John E Biaglow; Mark Dewhirst; Dennis B Leeper; Randy Burd; Stephen W Tuttle
Factors controlling oxygen utilization.
Advances in experimental medicine and biology 2005;566():317-23.
2005: John E Biaglow; Richard A Miller
The thioredoxin reductase/thioredoxin system: novel redox targets for cancer therapy.
Cancer biology & therapy 2005;4(1):6-13.
2004: Jun Guan; X Steven Wan; Zhaozong Zhou; Jeffrey Ware; Jeremiah J Donahue; John E Biaglow; Ann R Kennedy
Effects of dietary supplements on space radiation-induced oxidative stress in Sprague-Dawley rats.
Radiation research 2004;162(5):572-9.
2004: Ann R Kennedy; Jeffrey H Ware; Jun Guan; Jeremiah J Donahue; John E Biaglow; Zhaozong Zhou; Jelena Stewart; Marcelo Vazquez; X Steven Wan
Selenomethionine protects against adverse biological effects induced by space radiation.
Free radical biology & medicine 2004;36(2):259-66.
2003: Kristian Erickson; Rod D Braun; Daohai Yu; Jennifer Lanzen; David Wilson; David M. Brizel; Timothy W Secomb; John E Biaglow; Mark Dewhirst
Effect of longitudinal oxygen gradients on effectiveness of manipulation of tumor oxygenation.
Cancer research 2003;63(15):4705-12.
2003: John E Biaglow; Iraimoudi S Ayene; Cameron J Koch; Jeremiah Donahue; Thomas D Stamato; John J Mieyal; Stephen W Tuttle
Radiation response of cells during altered protein thiol redox.
Radiation research 2003;159(4):484-94.
2003: Randy Burd; Stephanie N Lavorgna; Constantine Daskalakis; Phyllis R Wachsberger; Miriam L Wahl; John E Biaglow; Craig W Stevens; Dennis B Leeper
Tumor oxygenation and acidification are increased in melanoma xenografts after exposure to hyperglycemia and meta-iodo-benzylguanidine.
Radiation research 2003;159(3):328-35.
2003: Intae Lee; Jerry D Glickson; Mark Dewhirst; Dennis B Leeper; Randy Burd; harish poptani; Lydie Nadal; W Gillies McKenna; John E Biaglow
Effect of mild hyperglycemia +/- meta-iodo-benzylguanidine on the radiation response of R3230 Ac tumors.
Advances in experimental medicine and biology 2003;530():177-86.
2003: John E Biaglow; Intae Lee; Jeremiah Donahue; Kathryn D Held; John J Mieyal; Mark Dewhirst; Stephen W Tuttle
Glutathione depletion or radiation treatment alters respiration and induces apoptosis in R3230Ac mammary carcinoma.
Advances in experimental medicine and biology 2003;530():153-64.
2002: Darren Magda; Nikolay Gerasimchuk; Philip Lecane; Richard A Miller; John E Biaglow; Jonathan L Sessler
Motexafin gadolinium reacts with ascorbate to produce reactive oxygen species.
Chemical communications (Cambridge, England) 2002;(22):2730-1.
2002: Iraimoudi S Ayene; Thomas D Stamato; Stanley K Mauldin; John E Biaglow; Stephen W Tuttle; Susan F Jenkins; Cameron J Koch
Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress.
The Journal of biological chemistry 2002;277(12):9929-35.
2001: Darren Magda; C Lepp; Nikolay Gerasimchuk; I Lee; Jonathan L Sessler; A Lin; John E Biaglow; Richard A Miller
Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species.
International journal of radiation oncology, biology, physics 2001;51(4):1025-36.
2001: Stacey A Snyder; Jennifer Lanzen; Rod D Braun; Gary Rosner; Timothy W Secomb; John E Biaglow; David M. Brizel; Mark Dewhirst
Simultaneous administration of glucose and hyperoxic gas achieves greater improvement in tumor oxygenation than hyperoxic gas alone.
International journal of radiation oncology, biology, physics 2001;51(2):494-506.
2001: Randy Burd; Phyllis R Wachsberger; John E Biaglow; Miriam L Wahl; Intae Lee; Dennis B Leeper
Absence of Crabtree effect in human melanoma cells adapted to growth at low pH: reversal by respiratory inhibitors.
Cancer research 2001;61(14):5630-5.
2000: Intae Lee; John E Biaglow; J Lee; M J Cho
Physiological mechanisms of radiation sensitization by pentoxifylline.
Anticancer research 2000;20(6B):4605-9.
2000: Iraimoudi S Ayene; Cameron J Koch; Stephen W Tuttle; Thomas D Stamato; ML Perez; John E Biaglow
Oxidation of cellular thiols by hydroxyethyldisulphide inhibits DNA double-strand-break rejoining in G6PD deficient mammalian cells.
International journal of radiation biology 2000;76(11):1523-31.
2000: L Tartier; Y L McCarey; John E Biaglow; Irene E Kochevar; Kathryn D Held
Apoptosis induced by dithiothreitol in HL-60 cells shows early activation of caspase 3 and is independent of mitochondria.
Cell death and differentiation 2000;7(10):1002-10.
2000: John E Biaglow; Iraimoudi S Ayene; Cameron J Koch; Jeremiah Donahue; Thomas D Stamato; Stephen W Tuttle
G6PD deficient cells and the bioreduction of disulfides: effects of DHEA, GSH depletion and phenylarsine oxide.
Biochemical and biophysical research communications 2000;273(3):846-52.
2000: Stephen W Tuttle; Thomas D Stamato; ML Perez; John E Biaglow
Glucose-6-phosphate dehydrogenase and the oxidative pentose phosphate cycle protect cells against apoptosis induced by low doses of ionizing radiation.
Radiation research 2000;153(6):781-7.
2000: John E Biaglow; Jeremiah Donahue; Stephen W Tuttle; Kathryn D Held; C Chrestensen; John J Mieyal
A method for measuring disulfide reduction by cultured mammalian cells: relative contributions of glutathione-dependent and glutathione-independent mechanisms.
Analytical biochemistry 2000;281(1):77-86.
1999: Alexander V Kachur; Cameron J Koch; John E Biaglow
Mechanism of copper-catalyzed autoxidation of cysteine.
Free radical research 1999;31(1):23-34.
1998: John E Biaglow; Yefim Manevich; Dennis B Leeper; Britton Chance; Mark Dewhirst; W Timothy Jenkins; Stephen W Tuttle; Krzysztof Wroblewski; Jerry D Glickson; C Stevens; Sydney Evans
MIBG inhibits respiration: potential for radio- and hyperthermic sensitization.
International journal of radiation oncology, biology, physics 1998;42(4):871-6.
1998: Stephen W Tuttle; A M Horan; Cameron J Koch; Kathryn D Held; Yefim Manevich; John E Biaglow
Radiation-sensitive tyrosine phosphorylation of cellular proteins: sensitive to changes in GSH content induced by pretreatment with N-acetyl-L-cysteine or L-buthionine-S,R-sulfoximine.
International journal of radiation oncology, biology, physics 1998;42(4):833-8.
1998: John E Biaglow; Cameron J Koch; Stephen W Tuttle; Yefim Manevich; Iraimoudi S Ayene; Eric J Bernhard; W Gillies McKenna; Alexander V Kachur
The measurement of bioreductive capacity of tumor cells using methylene blue.
International journal of radiation oncology, biology, physics 1998;42(4):769-73.
1998: Alexander V Kachur; Stephen W Tuttle; John E Biaglow
Autoxidation of ferrous ion complexes: a method for the generation of hydroxyl radicals.
Radiation research 1998;150(4):475-82.
1998: Alexander V Kachur; Cameron J Koch; John E Biaglow
Mechanism of copper-catalyzed oxidation of glutathione.
Free radical research 1998;28(3):259-69.
1997: Yefim Manevich; Kathryn D Held; John E Biaglow
Coumarin-3-carboxylic acid as a detector for hydroxyl radicals generated chemically and by gamma radiation.
Radiation research 1997;148(6):580-91.
1997: John E Biaglow; Alexander V Kachur
The generation of hydroxyl radicals in the reaction of molecular oxygen with polyphosphate complexes of ferrous ion.
Radiation research 1997;148(2):181-7.
1997: John E Biaglow; george cerniglia; Stephen W Tuttle; Vincent J Bakanauskas; C Stevens; Gillies McKenna
Effect of oncogene transformation of rat embryo cells on cellular oxygen consumption and glycolysis.
Biochemical and biophysical research communications 1997;235(3):739-42.
1997: george cerniglia; David F Wilson; M Pawlowski; Sergei Vinogradov; John E Biaglow
Intravascular oxygen distribution in subcutaneous 9L tumors and radiation sensitivity.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;82(6):1939-45.
1997: Alexander V Kachur; Yefim Manevich; John E Biaglow
Effect of purine nucleoside phosphates on OH-radical generation by reaction of Fe2+ with oxygen.
Free radical research 1997;26(5):399-408.
1997: Alexander V Kachur; Kathryn D Held; Cameron J Koch; John E Biaglow
Mechanism of production of hydroxyl radicals in the copper-catalyzed oxidation of dithiothreitol.
Radiation research 1997;147(4):409-15.
1997: AR Giandomenico; G E Cerniglia; John E Biaglow; Craig W Stevens; Cameron J Koch
The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide.
Free radical biology & medicine 1997;23(3):426-34.
1997: John E Biaglow; Yefim Manevich; F Uckun; Kathryn D Held
Quantitation of hydroxyl radicals produced by radiation and copper-linked oxidation of ascorbate by 2-deoxy-D-ribose method.
Free radical biology & medicine 1997;22(7):1129-38.
1996: M Pavlovic; K Wróblewski; Yefim Manevich; S Kim; John E Biaglow
The importance of choice of anaesthetics in studying radiation effects in the 9L rat glioma.
The British journal of cancer. Supplement 1996;27():S222-5.
1996: Stephen W Tuttle; Ruth J Muschel; Eric J Bernhard; W Gillies McKenna; John E Biaglow
Decreased ability of cells overexpressing MYC proteins to reduce peroxide and hydroperoxides.
The British journal of cancer. Supplement 1996;27():S140-44.
1996: John E Biaglow; Kathryn D Held; Yefim Manevich; Stephen W Tuttle; Alexander V Kachur; F Uckun
Role of guanosine triphosphate in ferric ion-linked Fenton chemistry.
Radiation research 1996;145(5):554-62.
1996: Kathryn D Held; F C Sylvester; Karen L Hopcia; John E Biaglow
Role of Fenton chemistry in thiol-induced toxicity and apoptosis.
Radiation research 1996;145(5):542-53.
1995: S H Kennedy; Yefim Manevich; John E Biaglow
Benzoyl peroxide acts as a promoter of radiation induced malignant transformation in vitro.
Biochemical and biophysical research communications 1995;212(1):118-25.
1994: Kathryn D Held; John E Biaglow
Mechanisms for the oxygen radical-mediated toxicity of various thiol-containing compounds in cultured mammalian cells.
Radiation research 1994;139(1):15-23.
1994: Stephen W Tuttle; L Hazard; Cameron J Koch; James B Mitchell; C Norman Coleman; John E Biaglow
Bioreductive metabolism of SR-4233 (WIN 59075) by whole cell suspensions under aerobic and hypoxic conditions: role of the pentose cycle and implications for the mechanism of cytotoxicity observed in air.
International journal of radiation oncology, biology, physics 1994;29(2):357-62.
1993: Kathryn D Held; Stephen W Tuttle; John E Biaglow
Role of the pentose cycle in oxygen radical-mediated toxicity of the thiol-containing radioprotector dithiothreitol in mammalian cells.
Radiation research 1993;134(3):383-9.
1993: Kathryn D Held; John E Biaglow
Role of copper in the oxygen radical-mediated toxicity of the thiol-containing radioprotector dithiothreitol in mammalian cells.
Radiation research 1993;134(3):375-82.
1992: Stephen W Tuttle; Marie E Varnes; James B Mitchell; John E Biaglow
Sensitivity to chemical oxidants and radiation in CHO cell lines deficient in oxidative pentose cycle activity.
International journal of radiation oncology, biology, physics 1992;22(4):671-5.
1992: John E Biaglow; James B Mitchell; Kathryn D Held
The importance of peroxide and superoxide in the X-ray response.
International journal of radiation oncology, biology, physics 1992;22(4):665-9.
1991: Kathryn D Held; E R Epp; S Awad; John E Biaglow
Postirradiation sensitization of mammalian cells by the thiol-depleting agent dimethyl fumarate.
Radiation research 1991;127(1):75-80.
1990: W Gillies McKenna; M C Weiss; V J Bakanauskas; H Sandler; M L Kelsten; John E Biaglow; Stephen W Tuttle; B Endlich; C Clifton Ling; Ruth J Muschel
The role of the H-ras oncogene in radiation resistance and metastasis.
International journal of radiation oncology, biology, physics 1990;18(4):849-59.
1989: John E Biaglow; Marie E Varnes; E R Epp; E P Clark; Stephen W Tuttle; Kathryn D Held
Role of glutathione in the aerobic radiation response.
International journal of radiation oncology, biology, physics 1989;16(5):1311-4.
1989: E R Epp; Kathryn D Held; E P Clark; John E Biaglow
Effect of varying the concentration of damage restituting species in the radical repair model.
International journal of radiation oncology, biology, physics 1989;16(5):1219-23.
1989: John E Biaglow; Marie E Varnes; E R Epp; E P Clark; Stephen W Tuttle; Kathryn D Held
Role of glutathione and other thiols in cellular response to radiation and drugs.
Drug metabolism reviews 1989;20(1):1-12.
1988: Kathryn D Held; E R Epp; E P Clark; John E Biaglow
Effect of dimethyl fumarate on the radiation sensitivity of mammalian cells in vitro.
Radiation research 1988;115(3):495-502.
1988: L A Dethlefsen; C M Lehman; John E Biaglow; V M Peck
Toxic effects of acute glutathione depletion by buthionine sulfoximine and dimethylfumarate on murine mammary carcinoma cells.
Radiation research 1988;114(2):215-24.
1988: John E Biaglow; Marie E Varnes; E R Epp; E P Clark
Antioxidant and redox enzymes in radioprotection.
Pharmacology & therapeutics 1988;39(1-3):275-86.
1988: John E Biaglow; Marie E Varnes; E R Epp; E P Clark; Stephen W Tuttle; Kathryn D Held
Cellular protection against damage by hydroperoxides: role of glutathione.
Basic life sciences 1988;49():567-73.
1986: E P Clark; E R Epp; M Morse-Gaudio; John E Biaglow
The role of glutathione in the aerobic radioresponse. I. Sensitization and recovery in the absence of intracellular glutathione.
Radiation research 1986;108(3):238-50.
1986: Marie E Varnes; L A Dethlefsen; John E Biaglow
The effect of pH on potentially lethal damage recovery in A549 cells.
Radiation research 1986;108(1):80-90.
1986: L A Dethlefsen; John E Biaglow; V M Peck; D N Ridinger
Toxic effects of extended glutathione depletion by buthionine sulfoximine on murine mammary carcinoma cells.
International journal of radiation oncology, biology, physics 1986;12(7):1157-60.
1986: John E Biaglow; Marie E Varnes; Stephen W Tuttle; Nancy L Oleinick; K Glazier; E P Clark; E R Epp; L A Dethlefsen
The effect of L-buthionine sulfoximine on the aerobic radiation response of A549 human lung carcinoma cells.
International journal of radiation oncology, biology, physics 1986;12(7):1139-42.
1986: Stephen W Tuttle; John E Biaglow; Marie E Varnes; L L Donahue; E P Clark; E R Epp
Enhancement in the aerobic toxicity of misonidazole and SR-2508 by buthionine sulfoximine and 4-hydroxypyrazole: the role of hydrogen peroxide.
International journal of radiation oncology, biology, physics 1986;12(7):1161-4.
1986: L Donahue; John E Biaglow; Marie E Varnes
Use of the oxidase electrode to determine tumor cell metabolism of peroxide.
Advances in experimental medicine and biology 1986;200():573-81.
1986: Marie E Varnes; John E Biaglow; Stephen W Tuttle
Role of cellular non-protein thiols in oxygen consumption and peroxide reduction.
Advances in experimental medicine and biology 1986;200():565-71.
1986: John E Biaglow; Marie E Varnes; L Roizen-Towle; E P Clark; E R Epp; M B Astor; E J Hall
Biochemistry of reduction of nitro heterocycles.
Biochemical pharmacology 1986;35(1):77-90.
1984: M B Astor; E J Hall; John E Biaglow; B Hartog
Effects of D,L-buthionine-S,R-sulfoximine on cellular thiol levels and the oxygen effect in Chinese hamster V79 cells.
International journal of radiation oncology, biology, physics 1984;10(8):1239-42.
1984: John E Biaglow; Marie E Varnes; E R Epp; E P Clark; M Astor
Factors involved in depletion of glutathione from A549 human lung carcinoma cells: implications for radiotherapy.
International journal of radiation oncology, biology, physics 1984;10(8):1221-7.
1984: Marie E Varnes; Stephen W Tuttle; John E Biaglow
Nitroheterocycle metabolism in mammalian cells. Stimulation of the hexose monophosphate shunt.
Biochemical pharmacology 1984;33(10):1671-7.
1984: E P Clark; E R Epp; John E Biaglow; M Morse-Gaudio; E Zachgo
Glutathione depletion, radiosensitization, and misonidazole potentiation in hypoxic Chinese hamster ovary cells by buthionine sulfoximine.
Radiation research 1984;98(2):370-80.
1984: Marie E Varnes; John E Biaglow; L Donahue; Stephen W Tuttle
Effects of glucose and thiol depletion on chemically-induced peroxide production in mammalian cells.
Advances in experimental medicine and biology 1984;180():663-72.
1983: John E Biaglow; E P Clark; E R Epp; M Morse-Guadio; Marie E Varnes; J B Mitchell
Nonprotein thiols and the radiation response of A549 human lung carcinoma cells.
International journal of radiation biology and related studies in physics, chemistry, and medicine 1983;44(5):489-95.
1983: John E Biaglow; Marie E Varnes; E P Clark; E R Epp
The role of thiols in cellular response to radiation and drugs.
Radiation research 1983;95(3):437-55.
1983: Marie E Varnes; Stephen W Tuttle; John E Biaglow
The use of a peroxidase electrode to measure the effects of nitro compounds on intact cells.
Advances in experimental medicine and biology 1983;159():49-61.
1982: John E Biaglow; Marie E Varnes; M Astor; E J Hall
Non-protein thiols and cellular response to drugs and radiation.
International journal of radiation oncology, biology, physics 1982;8(3-4):719-23.
1982: E J Hall; M Astor; John E Biaglow; J C Parham
The enhanced sensitivity of mammalian cells to killing by X rays after prolonged exposure to several nitroimidazoles.
International journal of radiation oncology, biology, physics 1982;8(3-4):447-51.
1982: M Astor; E J Hall; J Martin; M Flynn; John E Biaglow; J C Parham
Radiosensitizing and cytotoxic properties of ortho-substituted 4- and 5-nitroimidazoles: role of NPSH reactivity.
International journal of radiation oncology, biology, physics 1982;8(3-4):409-13.
1982: M Astor; E J Hall; John E Biaglow; J C Parham
Newly synthesized hypoxia-mediated drugs as radiosensitizers and cytotoxic agents.
International journal of radiation oncology, biology, physics 1982;8(1):75-83.
1981: John E Biaglow; Marie E Varnes; M Astor; E J Hall
Mechanism of misonidazole-linked cytotoxicity and altered radiation response: role of cellular thiols.
The British journal of radiology 1981;54(647):1006-8.