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John Reynolds

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Co-Publications
Name
30
Meikle, Murray
24
Hembry, Rosalind
13
Murphy, Gillian
11
Atkinson, Susan
8
Hill, Peter
5
Bord, Sharyn
5
Docherty, Andrew
4
Papaioannou, Stelios
3
Compston, Juliet
2
Cowell, S
2
Horner, A
2
Stanton, Heather
2
Tumber, Anthony
1
Twetman, Svante
1
Ullbro, Christer

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Publications

TOP 3
Ullbro Christer; Crossner Claes-Göran; Nederfors Tommy; Parhar Ranjit; Al Mohanna Futwan; Meikle Murray C; Reynolds John J; Twetman Svante
Cytokines, matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 in gingival crevicular fluid from patients with Papillon-Lefèvre syndrome.
Tumber A; Papaioannou S; Breckon J; Meikle M C; Reynolds J J; Hill P A
The effects of serine proteinase inhibitors on bone resorption in vitro.
Dew G; Murphy G; Stanton H; Vallon R; Angel P; Reynolds J J; Hembry R M
Localisation of matrix metalloproteinases and TIMP-2 in resorbing mouse bone.

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All Publications

2004: Ullbro Christer; Crossner Claes-Göran; Nederfors Tommy; Parhar Ranjit; Al Mohanna Futwan; Meikle Murray C; Reynolds John J; Twetman Svante
Cytokines, matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 in gingival crevicular fluid from patients with Papillon-Lefèvre syndrome.
Acta odontologica Scandinavica 2004;62(2):70-4.
2003: Tumber A; Papaioannou S; Breckon J; Meikle M C; Reynolds J J; Hill P A
The effects of serine proteinase inhibitors on bone resorption in vitro.
The Journal of endocrinology 2003;178(3):437-47.
2000: Dew G; Murphy G; Stanton H; Vallon R; Angel P; Reynolds J J; Hembry R M
Localisation of matrix metalloproteinases and TIMP-2 in resorbing mouse bone.
Cell and tissue research 2000;299(3):385-94.
1999: Breckon J J; Papaioannou S; Kon L W; Tumber A; Hembry R M; Murphy G; Reynolds J J; Meikle M C
Stromelysin (MMP-3) synthesis is up-regulated in estrogen-deficient mouse osteoblasts in vivo and in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(11):1880-90.
1998: Cowell S; Knäuper V; Stewart M L; D'Ortho M P; Stanton H; Hembry R M; López-Otín C; Reynolds J J; Murphy G
Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3.
The Biochemical journal 1998;331 ( Pt 2)():453-8.
1997: Bord S; Horner A; Hembry R M; Reynolds J J; Compston J E
Distribution of matrix metalloproteinases and their inhibitor, TIMP-1, in developing human osteophytic bone.
Journal of anatomy 1997;191 ( Pt 1)():39-48.
1997: Reynolds J J; Meikle M C
Mechanisms of connective tissue matrix destruction in periodontitis.
Periodontology 2000 1997;14():144-57.
1997: Reynolds J J; Meikle M C
The functional balance of metalloproteinases and inhibitors in tissue degradation: relevance to oral pathologies.
Journal of the Royal College of Surgeons of Edinburgh 1997;42(3):154-60.
1996: Bord S; Horner A; Hembry R M; Reynolds J J; Compston J E
Production of collagenase by human osteoblasts and osteoclasts in vivo.
Bone 1996;19(1):35-40.
1996: Breckon J J; Hembry R M; Reynolds J J; Meikle M C
Identification of matrix metalloproteinases and their inhibitor in the articular disc of the craniomandibular joint of the rabbit.
Archives of oral biology 1996;41(4):315-22.
1996: Reynolds J J
Collagenases and tissue inhibitors of metalloproteinases: a functional balance in tissue degradation.
Oral diseases 1996;2(1):70-6.
1995: Atkinson S J; Crabbe T; Cowell S; Ward R V; Butler M J; Sato H; Seiki M; Reynolds J J; Murphy G
Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes.
The Journal of biological chemistry 1995;270(51):30479-85.
1995: Meikle M C; Bord S; Hembry R M; Reynolds J J
The synthesis of collagenase, gelatinase-A (72 kDa) and -B (95 kDa), and TIMP-1 and -2 by human osteoblasts from normal and arthritic bone.
Bone 1995;17(3):255-60.
1995: Hembry R M; Bagga M R; Reynolds J J; Hamblen D L
Stromelysin, gelatinase A and TIMP-1 in prosthetic interface tissue: a role for macrophages in tissue remodelling.
Histopathology 1995;27(2):149-59.
1995: Allan J A; Docherty A J; Barker P J; Huskisson N S; Reynolds J J; Murphy G
Binding of gelatinases A and B to type-I collagen and other matrix components.
The Biochemical journal 1995;309 ( Pt 1)():299-306.
1995: Breckon J J; Hembry R M; Reynolds J J; Meikle M C
Matrix metalloproteinases and TIMP-1 localization at sites of osteogenesis in the craniofacial region of the rabbit embryo.
The Anatomical record 1995;242(2):177-87.
1995: Hill P A; Docherty A J; Bottomley K M; O'Connell J P; Morphy J R; Reynolds J J; Meikle M C
Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase.
The Biochemical journal 1995;308 ( Pt 1)():167-75.
1995: Hembry R M; Bagga M R; Reynolds J J; Hamblen D L
Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis.
Annals of the rheumatic diseases 1995;54(1):25-32.
1995: Hill P A; Reynolds J J; Meikle M C
Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function.
Endocrinology 1995;136(1):124-31.
1994: Ward R V; Atkinson S J; Reynolds J J; Murphy G
Cell surface-mediated activation of progelatinase A: demonstration of the involvement of the C-terminal domain of progelatinase A in cell surface binding and activation of progelatinase A by primary fibroblasts.
The Biochemical journal 1994;304 ( Pt 1)():263-9.
1994: Hill P A; Reynolds J J; Meikle M C
The purification and partial characterization of bone resorptive polypeptides from bovine bone matrix.
Biochimica et biophysica acta 1994;1201(2):193-202.
1994: Hill P A; Murphy G; Docherty A J; Hembry R M; Millican T A; Reynolds J J; Meikle M C
The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts.
Journal of cell science 1994;107 ( Pt 11)():3055-64.
1994: Meikle M C; Bord S; Hembry R M; Reynolds J J
Rabbit calvarial osteoblasts in culture constitutively synthesize progelatinase-A, and TIMP-1 and TIMP-2.
Biochimica et biophysica acta 1994;1224(1):99-102.
1994: Hill P A; Buttle D J; Jones S J; Boyde A; Murata M; Reynolds J J; Meikle M C
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
Journal of cellular biochemistry 1994;56(1):118-30.
1994: Meikle M C; Papaioannou S; Ratledge T J; Speight P M; Watt-Smith S R; Hill P A; Reynolds J J
Effect of poly DL-lactide--co-glycolide implants and xenogeneic bone matrix-derived growth factors on calvarial bone repair in the rabbit.
Biomaterials 1994;15(7):513-21.
1994: Meikle M C; Hembry R M; Holley J; Horton C; McFarlane C G; Reynolds J J
Immunolocalization of matrix metalloproteinases and TIMP-1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients.
Journal of periodontal research 1994;29(2):118-26.
1994: Breckon J J; Hembry R M; Reynolds J J; Meikle M C
Regional and temporal changes in the synthesis of matrix metalloproteinases and TIMP-1 during development of the rabbit mandibular condyle.
Journal of anatomy 1994;184 ( Pt 1)():99-110.
1994: Hembry R M; Bagga M R; Dingle J T; Thomas P P; Reynolds J J
Metalloproteinase production by rabbit articular cartilage: comparison of the effects of interleukin-1 alpha in vitro and in vivo.
Virchows Archiv : an international journal of pathology 1994;425(4):413-24.
1993: Hembry R M; Bagga M R; Murphy G; Henderson B; Reynolds J J
Rabbit models of arthritis: immunolocalization of matrix metalloproteinases and tissue inhibitor of metalloproteinase in synovium and cartilage.
The American journal of pathology 1993;143(2):628-42.
1993: Hill P A; Reynolds J J; Meikle M C
Inhibition of stimulated bone resorption in vitro by TIMP-1 and TIMP-2.
Biochimica et biophysica acta 1993;1177(1):71-4.
1993: Meikle M C; Mak W Y; Papaioannou S; Davies E H; Mordan N; Reynolds J J
Bone-derived growth factor release from poly(alpha-hydroxy acid) implants in vitro.
Biomaterials 1993;14(3):177-83.
1992: Atkinson S J; Ward R V; Reynolds J J; Murphy G
Cell-mediated degradation of type IV collagen and gelatin films is dependent on the activation of matrix metalloproteinases.
The Biochemical journal 1992;288 ( Pt 2)():605-11.
1992: Meikle M C; Bord S; Hembry R M; Compston J; Croucher P I; Reynolds J J
Human osteoblasts in culture synthesize collagenase and other matrix metalloproteinases in response to osteotropic hormones and cytokines.
Journal of cell science 1992;103 ( Pt 4)():1093-9.
1992: O'Shea M; Willenbrock F; Williamson R A; Cockett M I; Freedman R B; Reynolds J J; Docherty A J; Murphy G
Site-directed mutations that alter the inhibitory activity of the tissue inhibitor of metalloproteinases-1: importance of the N-terminal region between cysteine 3 and cysteine 13.
Biochemistry 1992;31(42):10146-52.
1992: Reynolds J J; Hembry R M
Immunolocalization of metalloproteinases and TIMP in normal and pathological tissues.
Matrix (Stuttgart, Germany). Supplement 1992;1():375-82.
1991: Ward R V; Atkinson S J; Slocombe P M; Docherty A J; Reynolds J J; Murphy G
Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes.
Biochimica et biophysica acta 1991;1079(2):242-6.
1991: Ward R V; Hembry R M; Reynolds J J; Murphy G
The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1.
The Biochemical journal 1991;278 ( Pt 1)():179-87.
1991: Meikle M C; McGarrity A M; Thomson B M; Reynolds J J
Bone-derived growth factors modulate collagenase and TIMP (tissue inhibitor of metalloproteinases) activity and type I collagen degradation by mouse calvarial osteoblasts.
Bone and mineral 1991;12(1):41-55.
1990: McFarlane C G; Reynolds J J; Meikle M C
The release of interleukin-1 beta, tumor necrosis factor-alpha and interferon-gamma by cultured peripheral blood mononuclear cells from patients with periodontitis.
Journal of periodontal research 1990;25(4):207-14.
1990: Heath J K; Reynolds J J; Meikle M C
Osteopetrotic (grey-lethal) bone produces collagenase and TIMP in organ culture: regulation by vitamin A.
Biochemical and biophysical research communications 1990;168(3):1171-6.
1990: Green D D; Hembry R M; Atkinson S J; Reynolds J J; Meikle M C
Immunolocalization of collagenase and tissue inhibitor of metalloproteinases (TIMP) in mechanically deformed fibrous joints.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 1990;97(4):281-8.
1989: Thomson B M; Atkinson S J; McGarrity A M; Hembry R M; Reynolds J J; Meikle M C
Type I collagen degradation by mouse calvarial osteoblasts stimulated with 1,25-dihydroxyvitamin D-3: evidence for a plasminogen-plasmin-metalloproteinase activation cascade.
Biochimica et biophysica acta 1989;1014(2):125-32.
1989: Gavrilovic J; Hembry R M; Reynolds J J; Murphy G
Collagenase is expressed by rabbit VX2 tumour cells in syngeneic and xenogeneic hosts.
Matrix (Stuttgart, Germany) 1989;9(3):206-13.
1989: Meikle M C; Atkinson S J; Ward R V; Murphy G; Reynolds J J
Gingival fibroblasts degrade type I collagen films when stimulated with tumor necrosis factor and interleukin 1: evidence that breakdown is mediated by metalloproteinases.
Journal of periodontal research 1989;24(3):207-13.
1989: Brown C C; Hembry R M; Reynolds J J
Immunolocalization of metalloproteinases and their inhibitor in the rabbit growth plate.
The Journal of bone and joint surgery. American volume 1989;71(4):580-93.
1989: Murphy G; Hembry R M; McGarrity A M; Reynolds J J; Henderson B
Gelatinase (type IV collagenase) immunolocalization in cells and tissues: use of an antiserum to rabbit bone gelatinase that identifies high and low Mr forms.
Journal of cell science 1989;92 ( Pt 3)():487-95.
1989: Fell H B; Lawrence C E; Bagga M R; Hembry R M; Reynolds J J
The degradation of collagen in pig synovium in vitro and the effect of colchicine.
Matrix (Stuttgart, Germany) 1989;9(2):116-26.
1989: Murphy G; Ward R; Hembry R M; Reynolds J J; Kühn K; Tryggvason K
Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase.
The Biochemical journal 1989;258(2):463-72.
1987: Thomson B M; Atkinson S J; Reynolds J J; Meikle M C
Degradation of type I collagen films by mouse osteoblasts is stimulated by 1,25 dihydroxyvitamin D3 and inhibited by human recombinant TIMP (tissue inhibitor of metalloproteinases).
Biochemical and biophysical research communications 1987;148(2):596-602.
1987: Heath J K; Atkinson S J; Hembry R M; Reynolds J J; Meikle M C
Bacterial antigens induce collagenase and prostaglandin E2 synthesis in human gingival fibroblasts through a primary effect on circulating mononuclear cells.
Infection and immunity 1987;55(9):2148-54.
1987: Gavrilovic J; Hembry R M; Reynolds J J; Murphy G
Tissue inhibitor of metalloproteinases (TIMP) regulates extracellular type I collagen degradation by chondrocytes and endothelial cells.
Journal of cell science 1987;87 ( Pt 2)():357-62.
1986: Fell H B; Reynolds J J; Lawrence C E; Bagga M R; Glauert A M
The promotion and inhibition of collagen-breakdown in organ cultures of pig synovium: the requirement for serum components and the involvement of cyclic adenosine 3':5'-monophosphate (cAMP).
Collagen and related research 1986;6(1):51-75.
1984: Heath J K; Atkinson S J; Meikle M C; Reynolds J J
Mouse osteoblasts synthesize collagenase in response to bone resorbing agents.
Biochimica et biophysica acta 1984;802(1):151-4.
1984: Heath J K; Meikle M C; Atkinson S J; Reynolds J J
A factor synthesized by rabbit periosteal fibroblasts stimulates bone resorption and collagenase production by connective tissue cells in vitro.
Biochimica et biophysica acta 1984;800(3):301-5.

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