Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Kenner Rice

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Chemicals & Drugs

Anatomy

Brain

Concepts & Ideas

Procedures

Radioligand Assay

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
133
Rothman, Richard
100
Jacobson, Arthur
46
Dersch, Christina
35
Woods, James
30
Partilla, John
22
Xu, Heng
20
Bowen, Wayne
17
carroll, Frank
16
Flippen-Anderson, Judith
15
Xu, H
15
Chrousos, George
14
Skolnick, Phil
13
Coop, Andrew
13
Baumann, Michael
13
Jutkiewicz, Emily

Sign-in to see all Coauthors

Publications

TOP 3
Hutchinson M R; Ramos K M; Loram L C; Wieseler J; Sholar P W; Kearney J J; Lewis M T; Crysdale N Y; Zhang Y; Harrison J A; Maier S F; Rice K C; Watkins L R
Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats.
Watkins Linda R; Hutchinson Mark R; Rice Kenner C; Maier Steven F
The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia.
Li Jun-Xu; Unzeitig Alison; Javors Martin A; Rice Kenner C; Koek Wouter; France Charles P
Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), ketanserin, and (R)-(+)-{alpha}-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol (MDL100907) in rats.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Kenner Rice (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Hutchinson M R; Ramos K M; Loram L C; Wieseler J; Sholar P W; Kearney J J; Lewis M T; Crysdale N Y; Zhang Y; Harrison J A; Maier S F; Rice K C; Watkins L R
Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats.
Neuroscience 2009;164(4):1821-32.
2009: Watkins Linda R; Hutchinson Mark R; Rice Kenner C; Maier Steven F
The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia.
Trends in pharmacological sciences 2009;30(11):581-91.
2009: Li Jun-Xu; Unzeitig Alison; Javors Martin A; Rice Kenner C; Koek Wouter; France Charles P
Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), ketanserin, and (R)-(+)-{alpha}-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol (MDL100907) in rats.
The Journal of pharmacology and experimental therapeutics 2009;331(2):671-9.
2009: Kreibich Arati S; Briand Lisa; Cleck Jessica N; Ecke Laurel; Rice Kenner C; Blendy Julie A
Stress-induced potentiation of cocaine reward: a role for CRF R1 and CREB.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(12):2609-17.
2009: Davis Catherine M; Rice Kenner C; Riley Anthony L
Opiate-agonist induced taste aversion learning in the Fischer 344 and Lewis inbred rat strains: evidence for differential mu opioid receptor activation.
Pharmacology, biochemistry, and behavior 2009;93(4):397-405.
2009: Klejbor Ilona; Kucinski Aaron; Wersinger Scott R; Corso Thomas; Spodnik Jan H; Dziewiatkowski Jerzy; Morys Janusz; Hesse Renae A; Rice Kenner C; Miletich Robert; Stachowiak Ewa K; Stachowiak Michal K
Serotonergic hyperinnervation and effective serotonin blockade in an FGF receptor developmental model of psychosis.
Schizophrenia research 2009;113(2-3):308-21.
2009: Kimura Tomohiro; Cheng Kejun; Rice Kenner C; Gawrisch Klaus
Location, structure, and dynamics of the synthetic cannabinoid ligand CP-55,940 in lipid bilayers.
Biophysical journal 2009;96(12):4916-24.
2009: Sabino Valentina; Cottone Pietro; Zhao Yu; Iyer Malliga R; Steardo Luca; Steardo Luca; Rice Kenner C; Conti Bruno; Koob George F; Zorrilla Eric P
The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(6):1482-93.
2009: Francesconi Walter; Berton Fulvia; Repunte-Canonigo Vez; Hagihara Kazuki; Thurbon David; Lekic Dusan; Specio Sheila E; Greenwell Thomas N; Chen Scott A; Rice Kenner C; Richardson Heather N; O'Dell Laura E; Zorrilla Eric P; Morales Marisela; Koob George F; Sanna Pietro Paolo
Protracted withdrawal from alcohol and drugs of abuse impairs long-term potentiation of intrinsic excitability in the juxtacapsular bed nucleus of the stria terminalis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(17):5389-401.
2009: Nic Dhonnchadha B A; Fox R G; Stutz S J; Rice K C; Cunningham K A
Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model.
Behavioral neuroscience 2009;123(2):382-96.
2009: Greenwell Thomas N; Funk Cindy K; Cottone Pietro; Richardson Heather N; Chen Scott A; Rice Kenner C; Zorrilla Eric P; Koob George F
Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long- but not short-access rats.
Addiction biology 2009;14(2):130-43.
2009: Collins Gregory T; Truccone Andrew; Haji-Abdi Faiza; Newman Amy Hauck; Grundt Peter; Rice Kenner C; Husbands Stephen M; Greedy Benjamin M; Enguehard-Gueiffier Cecile; Gueiffier Alain; Chen Jianyong; Wang Shaomeng; Katz Jonathan L; Grandy David K; Sunahara Roger K; Woods James H
Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice.
The Journal of pharmacology and experimental therapeutics 2009;329(1):210-7.
2009: Kohut Stephen J; Roma Peter G; Davis Catherine M; Zernig Gerald; Saria Alois; Dominguez Juan M; Rice Kenner C; Riley Anthony L
The impact of early environmental rearing condition on the discriminative stimulus effects and Fos expression induced by cocaine in adult male and female rats.
Psychopharmacology 2009;203(2):383-97.
2009: Davis Catherine M; Stevenson Glenn W; Cañadas Fernando; Ullrich Thomas; Rice Kenner C; Riley Anthony L
Discriminative stimulus properties of naloxone in Long-Evans rats: assessment with the conditioned taste aversion baseline of drug discrimination learning.
Psychopharmacology 2009;203(2):421-9.
2009: Li Jun-Xu; Rice Kenner C; France Charles P
Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rhesus monkeys: antagonism and apparent pA2 analyses.
The Journal of pharmacology and experimental therapeutics 2009;328(3):976-81.
2009: Negus S Stevens; Rice Kenner C
Mechanisms of withdrawal-associated increases in heroin self-administration: pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(4):899-911.
2009: Do Carmo Gail Pereira; Folk John E; Rice Kenner C; Chartoff Elena; Carlezon William A; Negus S Stevens
The selective non-peptidic delta opioid agonist SNC80 does not facilitate intracranial self-stimulation in rats.
European journal of pharmacology 2009;604(1-3):58-65.
2009: Nie Zhiguo; Zorrilla Eric P; Madamba Samuel G; Rice Kenner C; Roberto Marissa; Siggins George Robert
Presynaptic CRF1 receptors mediate the ethanol enhancement of GABAergic transmission in the mouse central amygdala.
TheScientificWorldJournal 2009;9():68-85.
2008: Roma Peter G; Rinker Jennifer A; Serafine Katherine M; Chen Scott A; Barr Christina S; Cheng Kejun; Rice Kenner C; Riley Anthony L
Genetic and early environmental contributions to alcohol's aversive and physiological effects.
Pharmacology, biochemistry, and behavior 2008;91(1):134-9.
2008: Do Carmo Gail Pereira; Polt Robin; Bilsky Edward J; Rice Kenner C; Negus S Stevens
Behavioral pharmacology of the mu/delta opioid glycopeptide MMP2200 in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 2008;326(3):939-48.
2008: Zezula Josef; Singer Lisa; Przybyl Anna K; Hashimoto Akihiro; Dersch Christina M; Rothman Richard B; Deschamps Jeffrey; Lee Yong Sok; Jacobson Arthur E; Rice Kenner C
Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans.
Organic & biomolecular chemistry 2008;6(16):2868-83.
2008: Rutherford John M; Wang Jiabei; Xu Heng; Dersch Christina M; Partilla John S; Rice Kenner C; Rothman Richard B
Evidence for a mu-delta opioid receptor complex in CHO cells co-expressing mu and delta opioid peptide receptors.
Peptides 2008;29(8):1424-31.
2008: Hutchinson Mark R; Zhang Yingning; Brown Kimberley; Coats Benjamen D; Shridhar Mitesh; Sholar Paige W; Patel Sonica J; Crysdale Nicole Y; Harrison Jacqueline A; Maier Steven F; Rice Kenner C; Watkins Linda R
Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4).
The European journal of neuroscience 2008;28(1):20-9.
2008: Horn Thomas L; Harder J Brooks; Johnson William D; Curry Patrick T; Parchment Ralph E; Morrissey Robert L; Mellick Paul W; Calis Karim A; Gold Philip W; Rice Kenner C; Contoreggi Carlo; Charney Dennis S; Cizza Giovanni; Glaze Elizabeth R; Tomaszewski Joseph E; McCormick David L
Integration of in vivo and in vitro approaches to characterize the toxicity of Antalarmin, a corticotropin-releasing hormone receptor antagonist.
Toxicology 2008;248(1):8-17.
2008: Hsin Ling-Wei; Chang Li-Te; Rothman Richard B; Dersch Christina M; Jacobson Arthur E; Rice Kenner C
Design and synthesis of 2- and 3-substituted-3-phenylpropyl analogs of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: role of amino, fluoro, hydroxyl, methoxyl, methyl, methylene, and oxo substituents on affinity for the dopamine and serotonin transporters.
Journal of medicinal chemistry 2008;51(9):2795-806.
2008: Yang Xiaoju; Wang Shelun; Rice Kenner C; Munro Cynthia A; Wand Gary S
Restraint stress and ethanol consumption in two mouse strains.
Alcoholism, clinical and experimental research 2008;32(5):840-52.
2008: Pascoe John E; Williams Keith L; Mukhopadhyay Partha; Rice Kenner C; Woods James H; Ko Mei-Chuan
Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic-pituitary-adrenal axis in monkeys.
Psychoneuroendocrinology 2008;33(4):478-86.
2008: Li Jun-Xu; Rice Kenner C; France Charles P
Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 2008;324(2):827-33.
2008: Jutkiewicz Emily M; Baladi Michelle G; Folk John E; Rice Kenner C; Woods James H
The delta-opioid receptor agonist SNC80 [(+)-4-[alpha(R)-alpha-[(2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl]-(3-methoxybenzyl)-N,N-diethylbenzamide] synergistically enhances the locomotor-activating effects of some psychomotor stimulants, but not direct dopamine agonists, in rats.
The Journal of pharmacology and experimental therapeutics 2008;324(2):714-24.
2008: Reissig C J; Eckler J R; Rabin R A; Rice K C; Winter J C
The stimulus effects of 8-OH-DPAT: evidence for a 5-HT2A receptor-mediated component.
Pharmacology, biochemistry, and behavior 2008;88(3):312-7.
2008: Fantegrossi William E; Reissig Chad J; Katz Elyse B; Yarosh Haley L; Rice Kenner C; Winter Jerrold C
Hallucinogen-like effects of N,N-dipropyltryptamine (DPT): possible mediation by serotonin 5-HT1A and 5-HT2A receptors in rodents.
Pharmacology, biochemistry, and behavior 2008;88(3):358-65.
2007: Zhao Y; Valdez G R; Fekete E M; Rivier J E; Vale W W; Rice K C; Weiss F; Zorrilla E P
Subtype-selective corticotropin-releasing factor receptor agonists exert contrasting, but not opposite, effects on anxiety-related behavior in rats.
The Journal of pharmacology and experimental therapeutics 2007;323(3):846-54.
2007: Marinelli Peter W; Funk Douglas; Juzytsch Walter; Harding Stephen; Rice Kenner C; Shaham Yavin; Lê A D
The CRF1 receptor antagonist antalarmin attenuates yohimbine-induced increases in operant alcohol self-administration and reinstatement of alcohol seeking in rats.
Psychopharmacology 2007;195(3):345-55.
2007: Winter J C; Rice K C; Amorosi D J; Rabin R A
Psilocybin-induced stimulus control in the rat.
Pharmacology, biochemistry, and behavior 2007;87(4):472-80.
2007: Hiebel Anne-Cécile; Lee Yong Sok; Bilsky Edward; Giuvelis Denise; Deschamps Jeffrey R; Parrish Damon A; Aceto Mario D; May Everette L; Harris Louis S; Coop Andrew; Dersch Christina M; Partilla John S; Rothman Richard B; Cheng Kejun; Jacobson Arthur E; Rice Kenner C
Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure-activity relationships of a potent mu-agonist delta-antagonist and an exceedingly potent antinociceptive in the enantiomeric C9-substituted 5-(3-hydroxyphenyl)-N-phenylethylmorphan series.
Journal of medicinal chemistry 2007;50(16):3765-76.
2007: Kino Tomoshige; Boos Terrence L; Sulima Agnieszka; Siegel Elise M; Gold Philip W; Rice Kenner C; Chrousos George P
3-O-Formyl-20R,21-epoxyresibufogenin suppresses IL-6-type cytokine actions by targeting the glycoprotein 130 subunit: potential clinical implications.
The Journal of allergy and clinical immunology 2007;120(2):437-44.
2007: Wang Bin; You Zhi-Bing; Rice Kenner C; Wise Roy A
Stress-induced relapse to cocaine seeking: roles for the CRF(2) receptor and CRF-binding protein in the ventral tegmental area of the rat.
Psychopharmacology 2007;193(2):283-94.
2007: Collins Gregory T; Newman Amy Hauck; Grundt Peter; Rice Kenner C; Husbands Stephen M; Chauvignac Cédric; Chen Jianyong; Wang Shaomeng; Woods James H
Yawning and hypothermia in rats: effects of dopamine D3 and D2 agonists and antagonists.
Psychopharmacology 2007;193(2):159-70.
2007: Li Jun-Xu; Rice Kenner C; France Charles P
Behavioral effects of dipropyltryptamine in rats: evidence for 5-HT1A and 5-HT2A agonist activity.
Behavioural pharmacology 2007;18(4):283-8.
2007: Kino T; Rice K C; Chrousos G P
The PPARdelta agonist GW501516 suppresses interleukin-6-mediated hepatocyte acute phase reaction via STAT3 inhibition.
European journal of clinical investigation 2007;37(5):425-33.
2007: Cheng Kejun; Kim In Jong; Lee Mei-Jing; Adah Steven A; Raymond Tyler J; Bilsky Edward J; Aceto Mario D; May Everette L; Harris Louis S; Coop Andrew; Dersch Christina M; Rothman Richard B; Jacobson Arthur E; Rice Kenner C
Opioid ligands with mixed properties from substituted enantiomeric N-phenethyl-5-phenylmorphans. Synthesis of a micro-agonist delta-antagonist and delta-inverse agonists.
Organic & biomolecular chemistry 2007;5(8):1177-90.
2007: Gilbert Kathleen M; Boos Terrence L; Dersch Christina M; Greiner Elisabeth; Jacobson Arthur E; Lewis David; Matecka Dorota; Prisinzano Thomas E; Zhang Ying; Rothman Richard B; Rice Kenner C; Venanzi Carol A
DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods.
Bioorganic & medicinal chemistry 2007;15(2):1146-59.
2007: Funk Cindy K; Zorrilla Eric P; Lee Mei-Jing; Rice Kenner C; Koob George F
Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats.
Biological psychiatry 2007;61(1):78-86.
2007: Hutchinson Mark R; Bland Sondra T; Johnson Kirk W; Rice Kenner C; Maier Steven F; Watkins Linda R
Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward.
TheScientificWorldJournal 2007;7():98-111.
2006: Mello Nancy K; Negus S Stevens; Rice Kenner C; Mendelson Jack H
Effects of the CRF1 antagonist antalarmin on cocaine self-administration and discrimination in rhesus monkeys.
Pharmacology, biochemistry, and behavior 2006;85(4):744-51.
2006: Sabino Valentina; Cottone Pietro; Koob George F; Steardo Luca; Lee Mei J; Rice Kenner C; Zorrilla Eric P
Dissociation between opioid and CRF1 antagonist sensitive drinking in Sardinian alcohol-preferring rats.
Psychopharmacology 2006;189(2):175-86.
2006: Grakalic Ivana; Schindler Charles W; Baumann Michael H; Rice Kenner C; Riley Anthony L
Effects of stress modulation on morphine-induced conditioned place preferences and plasma corticosterone levels in Fischer, Lewis, and Sprague-Dawley rat strains.
Psychopharmacology 2006;189(3):277-86.
2006: Wood Susan K; Verhoeven Robert E; Savit Aaron Z; Rice Kenner C; Fischbach Peter S; Woods James H
Facilitation of cardiac vagal activity by CRF-R1 antagonists during swim stress in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(12):2580-90.
2006: Danielsson Ingela; Gasior Maciej; Stevenson Glenn W; Folk John E; Rice Kenner C; Negus S Stevens
Electroencephalographic and convulsant effects of the delta opioid agonist SNC80 in rhesus monkeys.
Pharmacology, biochemistry, and behavior 2006;85(2):428-34.
2006: Do Carmo Gail Pereira; Mello Nancy K; Rice Kenner C; Folk John E; Negus S Stevens
Effects of the selective delta opioid agonist SNC80 on cocaine- and food-maintained responding in rhesus monkeys.
European journal of pharmacology 2006;547(1-3):92-100.
2006: Ghitza Udi E; Gray Sarah M; Epstein David H; Rice Kenner C; Shaham Yavin
The anxiogenic drug yohimbine reinstates palatable food seeking in a rat relapse model: a role of CRF1 receptors.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(10):2188-96.
2006: Milman Anat; Weizman Ronit; Rigai Tova; Rice Kenner C; Pick Chaim G
Behavioral effects of opioid subtypes compared with benzodiazepines in the staircase paradigm.
Behavioural brain research 2006;170(1):141-7.
2006: Boos Terrence L; Greiner Elisabeth; Calhoun W Jason; Prisinzano Thomas E; Nightingale Barbara; Dersch Christina M; Rothman Richard B; Jacobson Arthur E; Rice Kenner C
Structure-activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter.
Bioorganic & medicinal chemistry 2006;14(11):3967-73.
2006: Jutkiewicz Emily M; Baladi Michelle G; Folk John E; Rice Kenner C; Woods James H
The convulsive and electroencephalographic changes produced by nonpeptidic delta-opioid agonists in rats: comparison with pentylenetetrazol.
The Journal of pharmacology and experimental therapeutics 2006;317(3):1337-48.
2006: Fox Meredith A; Stevenson Glenn W; Rice Kenner C; Riley Anthony L
Naloxone, not proglumide or MK-801, alters effects of morphine preexposure on morphine-induced taste aversions.
Pharmacology, biochemistry, and behavior 2006;84(1):169-77.
2006: Taylor Jennifer L; Bishop Christopher; Ullrich Thomas; Rice Kenner C; Walker Paul D
Serotonin 2A receptor antagonist treatment reduces dopamine D1 receptor-mediated rotational behavior but not L-DOPA-induced abnormal involuntary movements in the unilateral dopamine-depleted rat.
Neuropharmacology 2006;50(6):761-8.
2006: Greiner Elisabeth; Boos Terrence L; Prisinzano Thomas E; De Martino Maria G; Zeglis Brian; Dersch Christina M; Marcus Jamila; Partilla John S; Rothman Richard B; Jacobson Arthur E; Rice Kenner C
Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity.
Journal of medicinal chemistry 2006;49(5):1766-72.
2006: Gardell Luis R; King Tamara; Ossipov Michael H; Rice Kenner C; Lai Josephine; Vanderah Todd W; Porreca Frank
Opioid receptor-mediated hyperalgesia and antinociceptive tolerance induced by sustained opiate delivery.
Neuroscience letters 2006;396(1):44-9.
2006: Zhang Huina; Torregrossa Mary M; Jutkiewicz Emily M; Shi Yong-Gong; Rice Kenner C; Woods James H; Watson Stanley J; Ko M C
Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects.
The European journal of neuroscience 2006;23(4):984-94.
2006: Jutkiewicz Emily M; Torregrossa Mary M; Sobczyk-Kojiro Katarzyna; Mosberg Henry I; Folk John E; Rice Kenner C; Watson Stanley J; Woods James H
Behavioral and neurobiological effects of the enkephalinase inhibitor RB101 relative to its antidepressant effects.
European journal of pharmacology 2006;531(1-3):151-9.
2006: Fantegrossi W E; Harrington A W; Kiessel C L; Eckler J R; Rabin R A; Winter J C; Coop A; Rice K C; Woods J H
Hallucinogen-like actions of 5-methoxy-N,N-diisopropyltryptamine in mice and rats.
Pharmacology, biochemistry, and behavior 2006;83(1):122-9.
2005: Freeman Kevin B; Rice Kenner C; Riley Anthony L
Assessment of monoamine transporter inhibition in the mediation of cocaine-induced conditioned taste aversion.
Pharmacology, biochemistry, and behavior 2005;82(3):583-9.
2005: Gomez-Flores Ricardo; Caballero-Hernández Diana; Tamez-Guerra Reyes; Rodríguez-Padilla Cristina; Tamez-Guerra Patricia; Rice Kenner C; Hicks Mary E; Weber Richard J
Increased survival of tumor-bearing mice by the delta opioid SNC 80.
Anticancer research 2005;25(6C):4563-7.
2005: Torregrossa Mary M; Folk John E; Rice Kenner C; Watson Stanley J; Woods James H
Chronic administration of the delta opioid receptor agonist (+)BW373U86 and antidepressants on behavior in the forced swim test and BDNF mRNA expression in rats.
Psychopharmacology 2005;183(1):31-40.
2005: Jutkiewicz Emily M; Rice Kenner C; Traynor John R; Woods James H
Separation of the convulsions and antidepressant-like effects produced by the delta-opioid agonist SNC80 in rats.
Psychopharmacology 2005;182(4):588-96.
2005: Jutkiewicz Emily M; Kaminsky Sarah T; Rice Kenner C; Traynor John R; Woods James H
Differential behavioral tolerance to the delta-opioid agonist SNC80 ([(+)-4-[(alphaR)-alpha-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in Sprague-Dawley rats.
The Journal of pharmacology and experimental therapeutics 2005;315(1):414-22.
2005: Sulima Agnieszka; Prisinzano Thomas E; Spande Thomas; Deschamps Jeffrey R; Whittaker Noel; Hochberg Zeev; Jacobson Arthur E; Rice Kenner C
A concise method for the preparation of deuterium-labeled cortisone: synthesis of [6,7-2H]cortisone.
Steroids 2005;70(11):763-9.
2005: Fantegrossi William E; Harrington Andrew W; Eckler Justin R; Arshad Sadia; Rabin Richard A; Winter Jerrold C; Coop Andrew; Rice Kenner C; Woods James H
Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats.
Psychopharmacology 2005;181(3):496-503.
2005: Winter J C; Kieres A K; Zimmerman M D; Reissig C J; Eckler J R; Ullrich T; Rice K C; Rabin R A; Richards J B
The stimulus properties of LSD in C57BL/6 mice.
Pharmacology, biochemistry, and behavior 2005;81(4):830-7.
2005: Nightingale Barbara; Dersch Christina M; Boos Terrence L; Greiner Elisabeth; Calhoun William J; Jacobson Arthur E; Rice Kenner C; Rothman Richard B
Studies of the biogenic amine transporters. XI. Identification of a 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR12909) analog that allosterically modulates the serotonin transporter.
The Journal of pharmacology and experimental therapeutics 2005;314(2):906-15.
2005: Winter J C; Eckler J R; Rice K C; Rabin R A
Serotonergic/glutamatergic interactions: potentiation of phencyclidine-induced stimulus control by citalopram.
Pharmacology, biochemistry, and behavior 2005;81(3):694-700.
2005: Caballero-Hernández Diana; Weber Richard J; Hicks Mary E; Tamez-Guerra Reyes; Rodríguez-Padilla Cristina; Tamez-Guerra Patricia; Rice Kenner C; Ananthan Subramaniam; Gomez-Flores Ricardo
Potentiation of rat lymphocyte proliferation by novel non-peptidic synthetic opioids.
International immunopharmacology 2005;5(7-8):1271-8.
2005: Pick Chaim G; Chernes Yakov; Rigai Tova; Rice Kenner C; Schreiber Shaul
The antinociceptive effect of zolpidem and zopiclone in mice.
Pharmacology, biochemistry, and behavior 2005;81(3):417-23.
2005: Stevenson Glenn W; Folk John E; Rice Kenner C; Negus S Stevens
Interactions between delta and mu opioid agonists in assays of schedule-controlled responding, thermal nociception, drug self-administration, and drug versus food choice in rhesus monkeys: studies with SNC80 [(+)-4-[(alphaR)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide] and heroin.
The Journal of pharmacology and experimental therapeutics 2005;314(1):221-31.
2005: Jutkiewicz Emily M; Wood Susan K; Houshyar Hani; Hsin Ling-Wei; Rice Kenner C; Woods James H
The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats.
Psychopharmacology 2005;180(2):215-23.
2005: Wu Huifang; Thatcher Linn N; Bernard Denzil; Parrish Damon A; Deschamps Jeffrey R; Rice Kenner C; MacKerell Alexander D; Coop Andrew
Position of coordination of the lithium ion determines the regioselectivity of demethylations of 3,4-dimethoxymorphinans with L-selectride.
Organic letters 2005;7(13):2531-4.
2005: Stoffel Erin C; Ulibarri Catherine M; Folk John E; Rice Kenner C; Craft Rebecca M
Gonadal hormone modulation of mu, kappa, and delta opioid antinociception in male and female rats.
The journal of pain : official journal of the American Pain Society 2005;6(4):261-74.
2005: Herin David V; Liu Shijing; Ullrich Thomas; Rice Kenner C; Cunningham Kathryn A
Role of the serotonin 5-HT2A receptor in the hyperlocomotive and hyperthermic effects of (+)-3,4-methylenedioxymethamphetamine.
Psychopharmacology 2005;178(4):505-13.
2005: Jutkiewicz Emily M; Walker Nicholas P; Folk John E; Rice Kenner C; Portoghese Philip S; Woods James H; Traynor John R
Comparison of peptidic and nonpeptidic delta-opioid agonists on guanosine 5'-O-(3-[35S]thio)triphosphate ([35S]GTPgammaS) binding in brain slices from Sprague-Dawley rats.
The Journal of pharmacology and experimental therapeutics 2005;312(3):1314-20.
2005: Jiang Jian-Kang; Thomas Craig J; Neumann Susanne; Lu Xinping; Rice Kenner C; Gershengorn Marvin C
1-(Phenyl)isoquinoline carboxamides: a novel class of subtype selective inhibitors of thyrotropin-releasing hormone (TRH) receptors.
Bioorganic & medicinal chemistry letters 2005;15(3):733-6.
2004: Ayala Alejandro R; Pushkas Judy; Higley J Dee; Ronsaville Donna; Gold Philip W; Chrousos George P; Pacak Karel; Calis Karim A; Gerald Melissa; Lindell Stephen; Rice Kenner C; Cizza Giovanni
Behavioral, adrenal, and sympathetic responses to long-term administration of an oral corticotropin-releasing hormone receptor antagonist in a primate stress paradigm.
The Journal of clinical endocrinology and metabolism 2004;89(11):5729-37.
2004: Hashimoto Akihiro; Przybyl Anna K; Linders Joannes T M; Kodato Shinichi; Tian Xinrong; Deschamps Jeffrey R; George Clifford; Flippen-Anderson Judith L; Jacobson Arthur E; Rice Kenner C
Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans.
The Journal of organic chemistry 2004;69(16):5322-7.
2004: Kim In Jong; Dersch Christina M; Rothman Richard B; Jacobson Arthur E; Rice Kenner C
A critical structural determinant of opioid receptor interaction with phenolic 5-phenylmorphans.
Bioorganic & medicinal chemistry 2004;12(16):4543-50.
2004: Bishop Christopher; Tessmer Jennifer L; Ullrich Thomas; Rice Kenner C; Walker Paul D
Serotonin 5-HT2A receptors underlie increased motor behaviors induced in dopamine-depleted rats by intrastriatal 5-HT2A/2C agonism.
The Journal of pharmacology and experimental therapeutics 2004;310(2):687-94.
2004: Eckelman William C; Rice Kenner C; Contoreggi Carlo
New tools to monitor stress using non-invasive PET imaging.
Annals of the New York Academy of Sciences 2004;1018():487-94.
2004: Broadbear Jillian H; Winger Gail; Rivier Jean E; Rice Kenner C; Woods James H
Corticotropin-releasing hormone antagonists, astressin B and antalarmin: differing profiles of activity in rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(6):1112-21.
2004: Lindsey Kimberly P; Wilcox Kristin M; Votaw John R; Goodman Mark M; Plisson Christophe; Carroll F Ivy; Rice Kenner C; Howell Leonard L
Effects of dopamine transporter inhibitors on cocaine self-administration in rhesus monkeys: relationship to transporter occupancy determined by positron emission tomography neuroimaging.
The Journal of pharmacology and experimental therapeutics 2004;309(3):959-69.
2004: Yu Han; Kim In Jong; Folk John E; Tian Xinrong; Rothman Richard B; Baumann Michael H; Dersch Christina M; Flippen-Anderson Judith L; Parrish Damon; Jacobson Arthur E; Rice Kenner C
Synthesis and pharmacological evaluation of 3-(3,4-dichlorophenyl)-1-indanamine derivatives as nonselective ligands for biogenic amine transporters.
Journal of medicinal chemistry 2004;47(10):2624-34.
2004: Fantegrossi William E; Kiessel Christina Lynn; Leach P Tarn; Van Martin C; Karabenick Rachel Lynn; Chen X; Ohizumi Y; Ullrich Thomas; Rice Kenner C; Woods James H
Nantenine: an antagonist of the behavioral and physiological effects of MDMA in mice.
Psychopharmacology 2004;173(3-4):270-7.
2004: Jutkiewicz Emily M; Eller Erik B; Folk John E; Rice Kenner C; Traynor John R; Woods James H
Delta-opioid agonists: differential efficacy and potency of SNC80, its 3-OH (SNC86) and 3-desoxy (SNC162) derivatives in Sprague-Dawley rats.
The Journal of pharmacology and experimental therapeutics 2004;309(1):173-81.
2004: Torregrossa Mary M; Isgor Ceylan; Folk John E; Rice Kenner C; Watson Stanley J; Woods James H
The delta-opioid receptor agonist (+)BW373U86 regulates BDNF mRNA expression in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(4):649-59.
2004: Kodato Shinichi; Linders Joannes T M; Gu Xiao-Hui; Yamada Koichiro; Flippen-Anderson Judith L; Deschamps Jeffrey R; Jacobson Arthur E; Rice Kenner C
Synthesis of rac-(1R,4aR,9aR)-2-methyl-1,3,4,9a-tetrahydro-2H-1,4a-propanobenzofuro[2,3-c]pyridin-6-ol. An unusual double rearrangement leading to the ortho- and para-f oxide-bridged phenylmorphan isomers.
Organic & biomolecular chemistry 2004;2(3):330-6.
2004: Thompson Chad M; Wojno Heidi; Greiner Elisabeth; May Everette L; Rice Kenner C; Selley Dana E
Activation of G-proteins by morphine and codeine congeners: insights to the relevance of O- and N-demethylated metabolites at mu- and delta-opioid receptors.
The Journal of pharmacology and experimental therapeutics 2004;308(2):547-54.
2004: Greiner Elisabeth; Folk John E; Jacobson Arthur E; Rice Kenner C
A novel and facile preparation of bremazocine enantiomers through optically pure N-norbremazocines.
Bioorganic & medicinal chemistry 2004;12(1):233-8.
2004: Contoreggi Carlo; Rice Kenner C; Chrousos George
Nonpeptide corticotropin-releasing hormone receptor type 1 antagonists and their applications in psychosomatic disorders.
Neuroendocrinology 2004;80(2):111-23.
2003: Stevenson Glenn W; Folk John E; Linsenmayer David C; Rice Kenner C; Negus S Stevens
Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception.
The Journal of pharmacology and experimental therapeutics 2003;307(3):1054-64.
2003: Rothman Richard B; Jayanthi Subramaniam; Wang Xiaoying; Dersch Christina M; Cadet Jean L; Prisinzano Thomas; Rice Kenner C; Baumann Michael H
High-dose fenfluramine administration decreases serotonin transporter binding, but not serotonin transporter protein levels, in rat forebrain.
Synapse (New York, N.Y.) 2003;50(3):233-9.
2003: Jutkiewicz E M; Rice K C; Woods J H; Winsauer P J
Effects of the delta-opioid receptor agonist SNC80 on learning relative to its antidepressant-like effects in rats.
Behavioural pharmacology 2003;14(7):509-16.
2003: Kim In Jong; Ullrich Thomas; Janetka James W; Furness M Scott; Jacobson Arthur E; Rothman Richard B; Dersch Christina M; Flippen-Anderson Judith L; George Clifford; Rice Kenner C
Diaryldimethylpiperazine ligands with mu- and delta-opioid receptor affinity: Synthesis of (+)-4-[(alphaR)-alpha-(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide and (-)-4-[(alphaR)-alpha-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide.
Bioorganic & medicinal chemistry 2003;11(22):4761-8.
2003: Jagoda Elaine; Contoreggi Carlo; Lee Mei-Jing; Kao Chih-Hao K; Szajek Lawrence P; Listwak Sam; Gold Philip; Chrousos George; Greiner Elisabeth; Kim B Moon; Jacobson Arthur E; Rice Kenner C; Eckelman William
Autoradiographic visualization of corticotropin releasing hormone type 1 receptors with a nonpeptide ligand: synthesis of [(76)Br]MJL-1-109-2.
Journal of medicinal chemistry 2003;46(17):3559-62.
2003: Varga Eva V; Rubenzik Marc K; Stropova Dagmar; Sugiyama Masano; Grife Vanessa; Hruby Victor J; Rice Kenner C; Roeske William R; Yamamura Henry I
Converging protein kinase pathways mediate adenylyl cyclase superactivation upon chronic delta-opioid agonist treatment.
The Journal of pharmacology and experimental therapeutics 2003;306(1):109-15.
2003: Janetka James W; Furness M Scott; Zhang Xiaoyan; Coop Andrew; Folk John E; Mattson Mariena V; Jacobson Arthur E; Rice Kenner C
Enantioconvergent synthesis of (-)-(2R,5S)-1-allyl-2,5-dimethylpiperazine, an intermediate to delta-opioid receptor ligands.
The Journal of organic chemistry 2003;68(10):3976-80.
2003: Greiner Elisabeth; Prisinzano Thomas; Johnson II Edward M; Dersch Christina M; Marcus Jamila; Partilla John S; Rothman Richard B; Jacobson Arthur E; Rice Kenner C
Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.
Journal of medicinal chemistry 2003;46(8):1465-9.
2003: Lewis David; Zhang Ying; Prisinzano Thomas; Dersch Christina M; Rothman Richard B; Jacobson Arthur E; Rice Kenner C
Further exploration of 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]piperazine (GBR 12909): role of N-aromatic, N-heteroaromatic, and 3-oxygenated N-phenylpropyl substituents on affinity for the dopamine and serotonin transporter.
Bioorganic & medicinal chemistry letters 2003;13(7):1385-9.
2003: Przybyl Anna K; Flippen-Anderson Judith L; Jacobson Arthur E; Rice Kenner C
Practical and high-yield syntheses of dihydromorphine from tetrahydrothebaine and efficient syntheses of (8S)-8-bromomorphide.
The Journal of organic chemistry 2003;68(5):2010-3.
2003: Fantegrossi William E; Godlewski Tomek; Karabenick Rachel L; Stephens Jermaine M; Ullrich Thomas; Rice Kenner C; Woods James H
Pharmacological characterization of the effects of 3,4-methylenedioxymethamphetamine ("ecstasy") and its enantiomers on lethality, core temperature, and locomotor activity in singly housed and crowded mice.
Psychopharmacology 2003;166(3):202-11.
2003: Hsin Ling-Wei; Prisinzano Thomas; Wilkerson Chavon R; Dersch Christina M; Horel Robert; Jacobson Arthur E; Rothman Richard B; Rice Kenner C
Synthesis and dopamine transporter affinity of chiral 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2-hydroxypropyl)piperazines as potential cocaine abuse therapeutic agents.
Bioorganic & medicinal chemistry letters 2003;13(3):553-6.
2003: Ordaz-Sánchez Iván; Weber Richard J; Rice Kenner C; Zhang Xiaoyan; Rodríguez-Padilla C; Tamez-Guerra R; Méndez-Vázquez José L; Gómez-Flores R
Chemotaxis of human and rat leukocytes by the delta-selective non-peptidic opioid SNC 80.
Revista latinoamericana de microbiología 2003;45(1-2):16-23.
2002: Broadbear Jillian H; Winger Gail; Rice Kenner C; Woods James H
Antalarmin, a putative CRH-RI antagonist, has transient reinforcing effects in rhesus monkeys.
Psychopharmacology 2002;164(3):268-76.
2002: Negus S S; Bidlack J M; Mello N K; Furness M S; Rice K C; Brandt M R
Delta opioid antagonist effects of buprenorphine in rhesus monkeys.
Behavioural pharmacology 2002;13(7):557-70.
2002: Broom Daniel C; Nitsche Joshua F; Pintar John E; Rice Kenner C; Woods James H; Traynor John R
Comparison of receptor mechanisms and efficacy requirements for delta-agonist-induced convulsive activity and antinociception in mice.
The Journal of pharmacology and experimental therapeutics 2002;303(2):723-9.
2002: Dykstra Linda A; Granger Arthur L; Allen Richard M; Zhang Xiaoyan; Rice Kenner C
Antinociceptive effects of the selective delta opioid agonist SNC80 alone and in combination with mu opioids in the squirrel monkey titration procedure.
Psychopharmacology 2002;163(3-4):420-9.
2002: Broom Daniel C; Jutkiewicz Emily M; Folk John E; Traynor John R; Rice Kenner C; Woods James H
Convulsant activity of a non-peptidic delta-opioid receptor agonist is not required for its antidepressant-like effects in Sprague-Dawley rats.
Psychopharmacology 2002;164(1):42-8.
2002: Hashimoto Akihiro; Jacobson Arthur E; Rothman Richard B; Dersch Christina M; George Clifford; Flippen-Anderson Judith L; Rice Kenner C
Probes for narcotic receptor mediated phenomena. Part 28: new opioid antagonists from enantiomeric analogues of 5-(3-hydroxyphenyl)-N-phenylethylmorphan.
Bioorganic & medicinal chemistry 2002;10(10):3319-29.
2002: Broom Daniel C; Jutkiewicz Emily M; Rice Kenner C; Traynor John R; Woods James H
Behavioral effects of delta-opioid receptor agonists: potential antidepressants?
Japanese journal of pharmacology 2002;90(1):1-6.
2002: Prisinzano Thomas; Greiner Elisabeth; Johnson Edward M; Dersch Christina M; Marcus Jamila; Partilla John S; Rothman Richard B; Jacobson Arthur E; Rice Kenner C
Piperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909): high affinity ligands for the dopamine transporter.
Journal of medicinal chemistry 2002;45(19):4371-4.
2002: Roth Bryan L; Baner Karen; Westkaemper Richard; Siebert Daniel; Rice Kenner C; Steinberg SeAnna; Ernsberger Paul; Rothman Richard B
Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11934-9.
2002: Baumann Michael H; Phillips Jennifer M; Ayestas Mario A; Ali Syed F; Rice Kenner C; Rothman Richard B
Preclinical evaluation of GBR12909 decanoate as a long-acting medication for methamphetamine dependence.
Annals of the New York Academy of Sciences 2002;965():92-108.
2002: Fantegrossi William E; Ullrich Thomas; Rice Kenner C; Woods James H; Winger Gail
3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement.
Psychopharmacology 2002;161(4):356-64.
2002: Webster Elizabeth L; Barrientos Ruth M; Contoreggi Carlo; Isaac Mitchel G; Ligier Sophie; Gabry K Eddie; Chrousos George P; McCarthy Edward F; Rice Kenner C; Gold Philip W; Sternberg Esther M
Corticotropin releasing hormone (CRH) antagonist attenuates adjuvant induced arthritis: role of CRH in peripheral inflammation.
The Journal of rheumatology 2002;29(6):1252-61.
2002: Baumann Michael H; Ayestas Mario A; Sharpe Lawrence G; Lewis David B; Rice Kenner C; Rothman Richard B
Persistent antagonism of methamphetamine-induced dopamine release in rats pretreated with GBR12909 decanoate.
The Journal of pharmacology and experimental therapeutics 2002;301(3):1190-7.
2002: Broom Daniel C; Jutkiewicz Emily M; Folk John E; Traynor John R; Rice Kenner C; Woods James H
Nonpeptidic delta-opioid receptor agonists reduce immobility in the forced swim assay in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(6):744-55.
2002: Rothman Richard B; Carroll F Ivy; Morales Marisela; Rowley Daniel L; Rice Kenner C; Dersch Christina M; Donovan David M
Studies of the biogenic amine transporters. 10. Characterization of a novel cocaine binding site in brain membranes prepared from dopamine transporter knockout mice.
Synapse (New York, N.Y.) 2002;44(2):94-105.
2002: Hsin Ling-Wei; Dersch Christina M; Baumann Michael H; Stafford David; Glowa John R; Rothman Richard B; Jacobson Arthur E; Rice Kenner C
Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine.
Journal of medicinal chemistry 2002;45(6):1321-9.
2002: Ko M C H; Naughton N N; Traynor J R; Song M S; Woods J H; Rice K C; McKnight A T
Orphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptors.
British journal of pharmacology 2002;135(4):943-50.
2002: Stevenson Glenn W; Cañadas Fernando; Gomez-Serrano Maria; Ullrich Thomas; Zhang Xiaoyan; Rice Kenner C; Riley Antony L
Delta opioid discrimination learning in the rat: assessment with the selective delta agonist SNC80.
Pharmacology, biochemistry, and behavior 2002;71(1-2):283-92.
2002: Yu Han; Prisinzano Thomas; Dersch Christina M; Marcus Jamila; Rothman Richard B; Jacobson Arthur E; Rice Kenner C
Synthesis and biological activity of 8beta-substituted hydrocodone indole and hydromorphone indole derivatives.
Bioorganic & medicinal chemistry letters 2002;12(2):165-8.
2002: Hsin Ling-Wei; Tian Xinrong; Webster Elizabeth L; Coop Andrew; Caldwell Timothy M; Jacobson Arthur E; Chrousos George P; Gold Philip W; Habib Kamal E; Ayala Alejandro; Eckelman William C; Contoreggi Carlo; Rice Kenner C
CRHR1 Receptor binding and lipophilicity of pyrrolopyrimidines, potential nonpeptide corticotropin-releasing hormone type 1 receptor antagonists.
Bioorganic & medicinal chemistry 2002;10(1):175-83.
2002: Gabry K E; Chrousos G P; Rice K C; Mostafa R M; Sternberg E; Negrao A B; Webster E L; McCann S M; Gold P W
Marked suppression of gastric ulcerogenesis and intestinal responses to stress by a novel class of drugs.
Molecular psychiatry 2002;7(5):474-83, 433.
2001: Craft R M; Tseng A H; McNiel D M; Furness M S; Rice K C
Receptor-selective antagonism of opioid antinociception in female versus male rats.
Behavioural pharmacology 2001;12(8):591-602.
2001: Zhang Y; Joseph D B; Bowen W D; Flippen-Anderson J L; Dersch C M; Rothman R B; Jacobson A E; Rice K C
Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.
Journal of medicinal chemistry 2001;44(23):3937-45.
2001: Brandt M R; Furness M S; Rice K C; Fischer B D; Negus S S
Studies of tolerance and dependence with the delta-opioid agonist SNC80 in rhesus monkeys responding under a schedule of food presentation.
The Journal of pharmacology and experimental therapeutics 2001;299(2):629-37.
2001: Ullrich T; Dersch C M; Rothman R B; Jacobson A E; Rice K C
Derivatives of 17-(2-methylallyl)-substituted noroxymorphone: variation of the delta address and its effects on affinity and selectivity for the delta opioid receptor.
Bioorganic & medicinal chemistry letters 2001;11(21):2883-5.
2001: Fedorova I; Hashimoto A; Fecik R A; Hedrick M P; Hanus L O; Boger D L; Rice K C; Basile A S
Behavioral evidence for the interaction of oleamide with multiple neurotransmitter systems.
The Journal of pharmacology and experimental therapeutics 2001;299(1):332-42.
2001: Xu H; Lu Y F; Rice K C; Ananthan S; Rothman R B
SoRI 9409, a non-peptide opioid mu receptor agonist/delta receptor antagonist, fails to stimulate [35S]-GTP-gamma-S binding at cloned opioid receptors.
Brain research bulletin 2001;55(4):507-11.
2001: Xu H; Lu Y F; Thomas J B; Carroll F I; Rice K C; Rothman R B
Opioid peptide receptor studies. 15. Relative efficacy of 4-[(N-allyl-3-methyl-4-piperidinyl)phenylamino]-N,N-diethylbenzamide and related compounds at the cloned human delta-opioid receptor.
Synapse (New York, N.Y.) 2001;40(4):269-74.
2001: Gomez-Flores R; Rice K C; Zhang X; Weber R J
Increased tumor necrosis factor-alpha and nitric oxide production by rat macrophages following in vitro stimulation and intravenous administration of the delta-opioid agonist SNC 80.
Life sciences 2001;68(24):2675-84.
2001: Hosohata Y; Varga E V; Stropova D; Li X; Knapp R J; Hruby V J; Rice K C; Nagase H; Roeske W R; Yamamura H I
Mutation W284L of the human delta opioid receptor reveals agonist specific receptor conformations for G protein activation.
Life sciences 2001;68(19-20):2233-42.
2001: McLamore S; Ullrich T; Rothman R B; Xu H; Dersch C; Coop A; Davis P; Porreca F; Jacobson A E; Rice K C
Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.
Journal of medicinal chemistry 2001;44(9):1471-4.
2001: Brandt M R; Furness M S; Mello N K; Rice K C; Negus S S
Antinociceptive effects of delta-opioid agonists in Rhesus monkeys: effects on chemically induced thermal hypersensitivity.
The Journal of pharmacology and experimental therapeutics 2001;296(3):939-46.
2001: Stafford D; LeSage M G; Rice K C; Glowa J R
A comparison of cocaine, GBR 12909, and phentermine self-administration by rhesus monkeys on a progressive-ratio schedule.
Drug and alcohol dependence 2001;62(1):41-7.
2001: Tian X; Hsin L W; Webster E L; Contoreggi C; Chrousos G P; Gold P W; Habib K; Ayala A; Eckelman W C; Jacobson A E; Rice K C
The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type.
Bioorganic & medicinal chemistry letters 2001;11(3):331-3.
2001: Xu H; Hashimoto A; Rice K C; Jacobson A E; Thomas J B; Carroll F I; Lai J; Rothman R B
Opioid peptide receptor studies. 14. Stereochemistry determines agonist efficacy and intrinsic efficacy in the [(35)S]GTP-gamma-S functional binding assay.
Synapse (New York, N.Y.) 2001;39(1):64-9.
2001: Rothman R B; Baumann M H; Dersch C M; Romero D V; Rice K C; Carroll F I; Partilla J S
Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin.
Synapse (New York, N.Y.) 2001;39(1):32-41.
2000: Partilla J S; Dersch C M; Yu H; Rice K C; Rothman R B
Neurochemical neutralization of amphetamine-type stimulants in rat brain by the indatraline analog (-)-HY038.
Brain research bulletin 2000;53(6):821-6.
2000: Yu H; Rothman R B; Dersch C M; Partilla J S; Rice K C
Uptake and release effects of diethylpropion and its metabolites with biogenic amine transporters.
Bioorganic & medicinal chemistry 2000;8(12):2689-92.
2000: Gu X H; Yu H; Jacobson A E; Rothman R B; Dersch C M; George C; Flippen-Anderson J L; Rice K C
Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline.
Journal of medicinal chemistry 2000;43(25):4868-76.
2000: Zhang Y; Rothman R B; Dersch C M; de Costa B R; Jacobson A E; Rice K C
Synthesis and transporter binding properties of bridged piperazine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909).
Journal of medicinal chemistry 2000;43(25):4840-9.
2000: Kling M A; Carson R E; Borg L; Zametkin A; Matochik J A; Schluger J; Herscovitch P; Rice K C; Ho A; Eckelman W C; Kreek M J
Opioid receptor imaging with positron emission tomography and [(18)F]cyclofoxy in long-term, methadone-treated former heroin addicts.
The Journal of pharmacology and experimental therapeutics 2000;295(3):1070-6.
2000: Stafford D; Rice K C; Lewis D B; Glowa J R
Response requirements and unit dose modify the effects of GBR 12909 on cocaine-maintained behavior.
Experimental and clinical psychopharmacology 2000;8(4):539-48.
2000: Coop A; Jacobson A E; Aceto M D; Harris L S; Traynor J R; Woods J H; Rice K C
N-Cyclohexylethyl-N-noroxymorphindole: a mu-opioid preferring analogue of naltrindole.
Bioorganic & medicinal chemistry letters 2000;10(21):2449-51.
2000: Ullrich T; Rice K C
A practical synthesis of the serotonin 5-HT2A receptor antagonist MDL 100907, its enantiomer and their 3-phenolic derivatives as precursors for [11C]labeled PET ligands.
Bioorganic & medicinal chemistry 2000;8(10):2427-32.
2000: Briscoe R J; Cabrera C L; Baird T J; Rice K C; Woods J H
Antalarmin blockade of corticotropin releasing hormone-induced hypertension in rats.
Brain research 2000;881(2):204-7.
2000: Rothman R B; Partilla J S; Dersch C M; Carroll F I; Rice K C; Baumann M H
Methamphetamine dependence: medication development efforts based on the dual deficit model of stimulant addiction.
Annals of the New York Academy of Sciences 2000;914():71-81.
2000: Stevenson G W; Cañadas F; Zhang X; Rice K C; Riley A L
Morphine discriminative control is mediated by the mu opioid receptor: assessment of delta opioid substitution and antagonism.
Pharmacology, biochemistry, and behavior 2000;66(4):851-6.
2000: Hutchinson A C; Simpson G R; Randall J F; Zhang X; Calderon S N; Rice K C; Riley A L
Assessment of SNC 80 and naltrindole within a conditioned taste aversion design.
Pharmacology, biochemistry, and behavior 2000;66(4):779-87.
2000: Furness M S; Zhang X; Coop A; Jacobson A E; Rothman R B; Dersch C M; Xu H; Porreca F; Rice K C
Probes for narcotic receptor-mediated phenomena. 27. Synthesis and pharmacological evaluation of selective delta-opioid receptor agonists from 4-[(alphaR)-alpha-(2S,5R)-4-substituted-2, 5-dimethyl-1-piperazinyl-3-methoxybenzyl]-N,N-diethylbenzamides and their enantiomers.
Journal of medicinal chemistry 2000;43(16):3193-6.
2000: Habib K E; Weld K P; Rice K C; Pushkas J; Champoux M; Listwak S; Webster E L; Atkinson A J; Schulkin J; Contoreggi C; Chrousos G P; McCann S M; Suomi S J; Higley J D; Gold P W
Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6079-84.
2000: Baumann M H; Ayestas M A; Dersch C M; Brockington A; Rice K C; Rothman R B
Effects of phentermine and fenfluramine on extracellular dopamine and serotonin in rat nucleus accumbens: therapeutic implications.
Synapse (New York, N.Y.) 2000;36(2):102-13.
2000: Hsin L W; Webster E L; Chrousos G P; Gold P W; Eckelman W C; Contoreggi C; Rice K C
Synthesis and biological activity of fluoro-substituted pyrrolo[2,3-d]pyrimidines: the development of potential positron emission tomography imaging agents for the corticotropin-releasing hormone type 1 receptor.
Bioorganic & medicinal chemistry letters 2000;10(8):707-10.
2000: Rothman R B; Partilla J S; Baumann M H; Dersch C M; Carroll F I; Rice K C
Neurochemical neutralization of methamphetamine with high-affinity nonselective inhibitors of biogenic amine transporters: a pharmacological strategy for treating stimulant abuse.
Synapse (New York, N.Y.) 2000;35(3):222-7.
2000: Hosohata Y; Vanderah T W; Burkey T H; Ossipov M H; Kovelowski C J; Sora I; Uhl G R; Zhang X; Rice K C; Roeske W R; Hruby V J; Yamamura H I; Lai J; Porreca F
delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice.
European journal of pharmacology 2000;388(3):241-8.
2000: Wong M L; Kling M A; Munson P J; Listwak S; Licinio J; Prolo P; Karp B; McCutcheon I E; Geracioti T D; DeBellis M D; Rice K C; Goldstein D S; Veldhuis J D; Chrousos G P; Oldfield E H; McCann S M; Gold P W
Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism and corticotropin-releasing hormone.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):325-30.
1999: Zhang X; Rice K C; Calderon S N; Kayakiri H; Smith L; Coop A; Jacobson A E; Rothman R B; Davis P; Dersch C M; Porreca F
Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic delta opioid receptor ligands.
Journal of medicinal chemistry 1999;42(26):5455-63.
1999: Coop A; Pinto J; Wang L; McCullough K; Rothman R B; Dersch C; Jacobson A E; Rice K C
Delta opioid binding selectivity of 3-ether analogs of naltrindole.
Bioorganic & medicinal chemistry letters 1999;9(24):3435-8.
1999: Lewis D B; Matecka D; Zhang Y; Hsin L W; Dersch C M; Stafford D; Glowa J R; Rothman R B; Rice K C
Oxygenated analogues of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents.
Journal of medicinal chemistry 1999;42(24):5029-42.
1999: Heyliger S O; Jackson C; Rice K C; Rothman R B
Opioid peptide receptor studies. 10. Nor-BNI differentially inhibits kappa receptor agonist-induced G-protein activation in the guinea pig caudate: further evidence of kappa receptor heterogeneity.
Synapse (New York, N.Y.) 1999;34(4):256-65.
1999: Romero D V; Partilla J S; Zheng Q X; Heyliger S O; Ni Q; Rice K C; Lai J; Rothman R B
Opioid peptide receptor studies. 12. Buprenorphine is a potent and selective mu/kappa antagonist in the [35S]-GTP-gamma-S functional binding assay.
Synapse (New York, N.Y.) 1999;34(2):83-94.
1999: Ananthan S; Kezar H S; Carter R L; Saini S K; Rice K C; Wells J L; Davis P; Xu H; Dersch C M; Bilsky E J; Porreca F; Rothman R B
Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans.
Journal of medicinal chemistry 1999;42(18):3527-38.
1999: Brandt M R; Negus S S; Mello N K; Furness M S; Zhang X; Rice K C
Discriminative stimulus effects of the nonpeptidic delta-opioid agonist SNC80 in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1157-64.
1999: Coop A; Rothman R B; Dersch C; Partilla J; Porreca F; Davis P; Jacobson A E; Rice K C
delta Opioid affinity and selectivity of 4-hydroxy-3-methoxyindolomorphinan analogues related to naltrindole.
Journal of medicinal chemistry 1999;42(9):1673-9.
1999: Xu H; Lu Y F; Partilla J S; Zheng Q X; Wang J B; Brine G A; Carroll F I; Rice K C; Chen K X; Chi Z Q; Rothman R B
Opioid peptide receptor studies, 11: involvement of Tyr148, Trp318 and His319 of the rat mu-opioid receptor in binding of mu-selective ligands.
Synapse (New York, N.Y.) 1999;32(1):23-8.
1999: Wojnicki F H; Rothman R B; Rice K C; Glowa J R
Effects of phentermine on responding maintained under multiple fixed-ratio schedules of food and cocaine presentation in the rhesus monkey.
The Journal of pharmacology and experimental therapeutics 1999;288(2):550-60.
1999: Aceto M D; Harris L S; Abood M E; Rice K C
Stereoselective mu- and delta-opioid receptor-related antinociception and binding with (+)-thebaine.
European journal of pharmacology 1999;365(2-3):143-7.
1999: Wong M L; Webster E L; Spokes H; Phu P; Ehrhart-Bornstein M; Bornstein S; Park C S; Rice K C; Chrousos G P; Licinio J; Gold P W
Chronic administration of the non-peptide CRH type 1 receptor antagonist antalarmin does not blunt hypothalamic-pituitary-adrenal axis responses to acute immobilization stress.
Life sciences 1999;65(4):PL53-8.
1998: Zhang Y; Williams W; Torrence-Campbell C; Bowen W D; Rice K C
Characterization of novel N,N'-disubstituted piperazines as sigma receptor ligands.
Journal of medicinal chemistry 1998;41(25):4950-7.
1998: Nowak J E; Gomez-Flores R; Calderon S N; Rice K C; Weber R J
Rat natural killer cell, T cell and macrophage functions after intracerebroventricular injection of SNC 80.
The Journal of pharmacology and experimental therapeutics 1998;286(2):931-7.
1998: Ananthan S; Johnson C A; Carter R L; Clayton S D; Rice K C; Xu H; Davis P; Porreca F; Rothman R B
Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.
Journal of medicinal chemistry 1998;41(15):2872-81.
1998: Kubota H; Rothman R B; Dersch C; McCullough K; Pinto J; Rice K C
Synthesis and biological activity of 3-substituted 3-desoxynaltrindole derivatives.
Bioorganic & medicinal chemistry letters 1998;8(7):799-804.
1998: Bornstein S R; Webster E L; Torpy D J; Richman S J; Mitsiades N; Igel M; Lewis D B; Rice K C; Joost H G; Tsokos M; Chrousos G P
Chronic effects of a nonpeptide corticotropin-releasing hormone type I receptor antagonist on pituitary-adrenal function, body weight, and metabolic regulation.
Endocrinology 1998;139(4):1546-55.
1998: Rothman R B; Silverthorn M L; Glowa J R; Matecka D; Rice K C; Carroll F I; Partilla J S; Uhl G R; Vandenbergh D J; Dersch C M
Studies of the biogenic amine transporters. VII. Characterization of a novel cocaine binding site identified with [125I]RTI-55 in membranes prepared from human, monkey and guinea pig caudate.
Synapse (New York, N.Y.) 1998;28(4):322-38.
1998: Lu Y F; Xu H; Liu-Chen L Y; Chen C; Partilla J S; Brine G A; Carroll F I; Rice K C; Lai J; Porreca F; Sadee W; Rothman R B
Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor.
Synapse (New York, N.Y.) 1998;28(2):117-24.
1998: Ni Q; Xu H; Partilla J S; Rice K C; Matecka D; Calderon S N; Porreca F; Lai J; Schmidhammer H; Krassnig R; Rothman R B
Opioid peptide receptor studies. 9. Identification of a novel non-mu- non-delta-like opioid peptide binding site in rat brain.
Peptides 1998;19(6):1079-90.
1998: Xu H; Lu Y F; Partilla J S; Pinto J; Calderon S N; Matecka D; Rice K C; Lai J; Porreca F; Ananthan S; Rothman R B
Opioid peptide receptor studies. 8. One of the mouse brain deltaNCX binding sites is similar to the cloned mouse opioid delta receptor: further evidence for heterogeneity of delta opioid receptors.
Peptides 1998;19(2):343-50.
1997: Katsura Y; Zhang X; Homma K; Rice K C; Calderon S N; Rothman R B; Yamamura H I; Davis P; Flippen-Anderson J L; Xu H; Becketts K; Foltz E J; Porreca F
Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists.
Journal of medicinal chemistry 1997;40(18):2936-47.
1997: Quock R M; Hosohata Y; Knapp R J; Burkey T H; Hosohata K; Zhang X; Rice K C; Nagase H; Hruby V J; Porreca F; Roeske W R; Yamamura H I
Relative efficacies of delta-opioid receptor agonists at the cloned human delta-opioid receptor.
European journal of pharmacology 1997;326(1):101-4.
1997: Glowa J R; Rice K C; Matecka D; Rothman R B
Phentermine/fenfluramine decreases cocaine self-administration in rhesus monkeys.
Neuroreport 1997;8(6):1347-51.
1997: Matecka D; Lewis D; Rothman R B; Dersch C M; Wojnicki F H; Glowa J R; DeVries A C; Pert A; Rice K C
Heteroaromatic analogs of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as high-affinity dopamine reuptake inhibitors.
Journal of medicinal chemistry 1997;40(5):705-16.
1997: Calderon S N; Rice K C; Rothman R B; Porreca F; Flippen-Anderson J L; Kayakiri H; Xu H; Becketts K; Smith L E; Bilsky E J; Davis P; Horvath R
Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands.
Journal of medicinal chemistry 1997;40(5):695-704.
1996: Webster E L; Lewis D B; Torpy D J; Zachman E K; Rice K C; Chrousos G P
In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation.
Endocrinology 1996;137(12):5747-50.
1996: Matecka D; Rothman R B; Radesca L; de Costa B R; Dersch C M; Partilla J S; Pert A; Glowa J R; Wojnicki F H; Rice K C
Development of novel, potent, and selective dopamine reuptake inhibitors through alteration of the piperazine ring of 1-[2-(diphenylmethoxy)ethyl]-and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909).
Journal of medicinal chemistry 1996;39(24):4704-16.
1996: Glowa J R; Fantegrossi W E; Lewis D B; Matecka D; Rice K C; Rothman R B
Sustained decrease in cocaine-maintained responding in rhesus monkeys with 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-hydroxy-3-phenylpropyl) piperazinyl decanoate, a long-acting ester derivative of GBR 12909.
Journal of medicinal chemistry 1996;39(24):4689-91.
1996: Zhang Y; Williams W; Bowen W D; Rice K C
Synthesis and evaluation of aryl-substituted N-(arylethyl)-N-methyl-2-(1-pyrrolidinyl)ethylamines and corresponding arylacetamides for sigma receptor affinity.
Journal of medicinal chemistry 1996;39(18):3564-8.
1996: Knapp R J; Santoro G; De Leon I A; Lee K B; Edsall S A; Waite S; Malatynska E; Varga E; Calderon S N; Rice K C; Rothman R B; Porreca F; Roeske W R; Yamamura H I
Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors.
The Journal of pharmacology and experimental therapeutics 1996;277(3):1284-91.
1996: Bertha C M; Ellis M; Flippen-Anderson J L; Porreca F; Rothman R B; Davis P; Xu H; Becketts K; Rice K C
Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity.
Journal of medicinal chemistry 1996;39(10):2081-6.
1996: Yamada K; Rice K C; Flippen-Anderson J L; Eissenstat M A; Ward S J; Johnson M R; Howlett A C
(Aminoalkyl)indole isothiocyanates as potential electrophilic affinity ligands for the brain cannabinoid receptor.
Journal of medicinal chemistry 1996;39(10):1967-74.
1996: Elmer G I; Brockington A; Gorelick D A; Carrol F I; Rice K C; Matecka D; Goldberg S R; Rothman R B
Cocaine cross-sensitization to dopamine uptake inhibitors: unique effects of GBR12909.
Pharmacology, biochemistry, and behavior 1996;53(4):911-8.
1995: Bertha C M; Vilner B J; Mattson M V; Bowen W D; Becketts K; Xu H; Rothman R B; Flippen-Anderson J L; Rice K C
(E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype.
Journal of medicinal chemistry 1995;38(24):4776-85.
1995: Cha X Y; Xu H; Ni Q; Partilla J S; Rice K C; Matecka D; Calderon S N; Porreca F; Lai J; Rothman R B
Opioid peptide receptor studies. 4. Antisense oligodeoxynucleotide to the delta opioid receptor delineates opioid receptor subtypes.
Regulatory peptides 1995;59(2):247-53.
1995: Rothman R B; Xu H; Wang J B; Partilla J S; Kayakiri H; Rice K C; Uhl G R
Ligand selectivity of cloned human and rat opioid mu receptors.
Synapse (New York, N.Y.) 1995;21(1):60-4.
1995: Rothman R B; Silverthorn M L; Baumann M H; Goodman C B; Cadet J L; Matecka D; Rice K C; Carroll F I; Wang J B; Uhl G R
Studies of the biogenic amine transporters. VI. Characterization of a novel cocaine binding site, identified with [125I]RTI-55, in membranes prepared from whole rat brain minus caudate.
The Journal of pharmacology and experimental therapeutics 1995;274(1):385-95.
1995: Bowen W D; Bertha C M; Vilner B J; Rice K C
CB-64D and CB-184: ligands with high sigma 2 receptor affinity and subtype selectivity.
European journal of pharmacology 1995;278(3):257-60.
1995: Bertha C M; Flippen-Anderson J L; Rothman R B; Porreca F; Davis P; Xu H; Becketts K; Cha X Y; Rice K C
Probes for narcotic receptor-mediated phenomena. 20. Alteration of opioid receptor subtype selectivity of the 5-(3-hydroxyphenyl)morphans by application of the message-address concept: preparation of delta-opioid receptor ligands.
Journal of medicinal chemistry 1995;38(9):1523-37.
1995: Bilsky E J; Calderon S N; Wang T; Bernstein R N; Davis P; Hruby V J; McNutt R W; Rothman R B; Rice K C; Porreca F
SNC 80, a selective, nonpeptidic and systemically active opioid delta agonist.
The Journal of pharmacology and experimental therapeutics 1995;273(1):359-66.
1995: Silverthorn M L; Dersch C M; Baumann M H; Cadet J L; Partilla J S; Rice K C; Carroll F I; Becketts K M; Brockington A; Rothman R B
Studies of the biogenic amine transporters. V. Demonstration of two binding sites for the cocaine analog [125I]RTI-55 associated with the 5-HT transporter in rat brain membranes.
The Journal of pharmacology and experimental therapeutics 1995;273(1):213-22.
1995: Xu H; Goodman C B; Partilla J S; Ni Q; Kayakiri H; Rice K C; Rothman R B
6 beta-[125iodo]-3, 14-dihydroxy-17-methyl-4, 5 alpha-epoxymorphinan ([125I]IOXY-AGO): a potent and selective radioligand for opioid mu receptors.
Synapse (New York, N.Y.) 1995;19(2):105-11.
1995: Ni Q; Xu H; Partilla J S; de Costa B R; Rice K C; Kayakiri H; Rothman R B
Opioid peptide receptor studies. 3. Interaction of opioid peptides and other drugs with four subtypes of the kappa 2 receptor in guinea pig brain.
Peptides 1995;16(6):1083-95.
1995: Cha X Y; Xu H; Rice K C; Porreca F; Lai J; Ananthan S; Rothman R B
Opioid peptide receptor studies. 1. Identification of a novel delta-opioid receptor binding site in rat brain membranes.
Peptides 1995;16(2):191-8.
1994: Baumann M H; Char G U; De Costa B R; Rice K C; Rothman R B
GBR12909 attenuates cocaine-induced activation of mesolimbic dopamine neurons in the rat.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1216-22.
1994: Pinto J C; Potié F; Rice K C; Boring D; Johnson M R; Evans D M; Wilken G H; Cantrell C H; Howlett A C
Cannabinoid receptor binding and agonist activity of amides and esters of arachidonic acid.
Molecular pharmacology 1994;46(3):516-22.
1994: Bertha C M; Mattson M V; Flippen-Anderson J L; Rothman R B; Xu H; Cha X Y; Becketts K; Rice K C
A marked change of receptor affinity of the 2-methyl-5-(3-hydroxyphenyl)morphans upon attachment of an (E)-8-benzylidene moiety: synthesis and evaluation of a new class of sigma receptor ligands.
Journal of medicinal chemistry 1994;37(19):3163-70.
1994: Ni Q; Xu H; Partilla J S; de Costa B R; Rice K C; Borsodi A; Hosztafi S; Rothman R B
Dihydrocodeinone-hydrazone, dihydrocodeinone-oxime, naloxone-3-OMe-oxime, and clocinnamox fail to irreversibly inhibit opioid kappa receptor binding.
Neurochemical research 1994;19(9):1159-63.
1994: Calderon S N; Rothman R B; Porreca F; Flippen-Anderson J L; McNutt R W; Xu H; Smith L E; Bilsky E J; Davis P; Rice K C
Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(alpha R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3- methoxybenzyl]-N,N-diethylbenzamide (SNC 80): a highly selective, nonpeptide delta opioid receptor agonist.
Journal of medicinal chemistry 1994;37(14):2125-8.
1994: Rothman R B; Cadet J L; Akunne H C; Silverthorn M L; Baumann M H; Carroll F I; Rice K C; de Costa B R; Partilla J S; Wang J B
Studies of the biogenic amine transporters. IV. Demonstration of a multiplicity of binding sites in rat caudate membranes for the cocaine analog [125I]RTI-55.
The Journal of pharmacology and experimental therapeutics 1994;270(1):296-309.
1994: Akunne H C; Monn J A; Thurkauf A; Jacobson A E; Rice K C; Linders J T; Jiang Q; Porreca F; Rothman R B
An electrophilic affinity ligand based on (+)-MK801 distinguishes PCP site 1 from PCP site 2.
Neurochemical research 1994;19(4):385-9.
1994: Akunne H C; Dersch C M; Cadet J L; Baumann M H; Char G U; Partilla J S; de Costa B R; Rice K C; Carroll F I; Rothman R B
Studies of the biogenic amine transporters. III. Demonstration of two binding sites for [3H]GBR12935 and [3H]BTCP in rat caudate membranes.
The Journal of pharmacology and experimental therapeutics 1994;268(3):1462-75.
1994: Dersch C M; Akunne H C; Partilla J S; Char G U; de Costa B R; Rice K C; Carroll F I; Rothman R B
Studies of the biogenic amine transporters. 1. Dopamine reuptake blockers inhibit [3H]mazindol binding to the dopamine transporter by a competitive mechanism: preliminary evidence for different binding domains.
Neurochemical research 1994;19(2):201-8.
1993: Ni Q; Xu H; Partilla J S; de Costa B R; Rice K C; Rothman R B
Selective labeling of kappa 2 opioid receptors in rat brain by [125I]IOXY: interaction of opioid peptides and other drugs with multiple kappa 2a binding sites.
Peptides 1993;14(6):1279-93.
1993: Xu H; Partilla J S; de Costa B R; Rice K C; Rothman R B
Differential binding of opioid peptides and other drugs to two subtypes of opioid delta ncx binding sites in mouse brain: further evidence for delta receptor heterogeneity.
Peptides 1993;14(5):893-907.
1993: Linders J T; Monn J A; Mattson M V; George C; Jacobson A E; Rice K C
Synthesis and binding properties of MK-801 isothiocyanates; (+)-3-isothiocyanato-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten- 5,10-imine hydrochloride: a new, potent and selective electrophilic affinity ligand for the NMDA receptor-coupled phencyclidine binding site.
Journal of medicinal chemistry 1993;36(17):2499-507.
1993: Rothman R B; Lewis B; Dersch C; Xu H; Radesca L; de Costa B R; Rice K C; Kilburn R B; Akunne H C; Pert A
Identification of a GBR12935 homolog, LR1111, which is over 4,000-fold selective for the dopamine transporter, relative to serotonin and norepinephrine transporters.
Synapse (New York, N.Y.) 1993;14(1):34-9.
1993: Gu Z Q; Wong G; Dominguez C; de Costa B R; Rice K C; Skolnick P
Synthesis and evaluation of imidazo[1,5-a][1,4]benzodiazepine esters with high affinities and selectivities at "diazepam-insensitive" benzodiazepine receptors.
Journal of medicinal chemistry 1993;36(8):1001-6.
1993: Rothman R B; Xu H; Char G U; Kim A; De Costa B R; Rice K C; Zimmerman D M
Phenylpiperidine opioid antagonists that promote weight loss in rats have high affinity for the kappa 2B (enkephalin-sensitive) binding site.
Peptides 1993;14(1):17-20.
1993: Carson R E; Channing M A; Blasberg R G; Dunn B B; Cohen R M; Rice K C; Herscovitch P
Comparison of bolus and infusion methods for receptor quantitation: application to [18F]cyclofoxy and positron emission tomography.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(1):24-42.
1993: Rothman R B; Becketts K M; Radesca L R; de Costa B R; Rice K C; Carroll F I; Dersch C M
Studies of the biogenic amine transporters. II. A brief study on the use of [3H]DA-uptake-inhibition to transporter-binding-inhibition ratios for the in vitro evaluation of putative cocaine antagonists.
Life sciences 1993;53(17):PL267-72.
1993: Bowen W D; Tolentino P J; Kirschner B N; Varghese P; de Costa B R; Rice K C
Sigma receptors and signal transduction: negative modulation of signaling through phosphoinositide-linked receptor systems.
NIDA research monograph 1993;133():69-93.
1992: Rothman R B; Grieg N; Kim A; De Costa B R; Rice K C; Carroll F I; Pert A
Cocaine and GBR12909 produce equivalent motoric responses at different occupancy of the dopamine transporter.
Pharmacology, biochemistry, and behavior 1992;43(4):1135-42.
1992: Akunne H C; de Costa B R; Jacobson A E; Rice K C; Rothman R B
[3H] cocaine labels a binding site associated with the serotonin transporter in guinea pig brain: allosteric modulation by paroxetine.
Neurochemical research 1992;17(12):1275-83.
1992: Xu H; Partilla J S; de Costa B R; Rice K C; Rothman R B
Interaction of opioid peptides and other drugs with multiple delta ncx binding sites in rat brain: further evidence for heterogeneity.
Peptides 1992;13(6):1207-13.
1992: Rothman R B; Mahboubi A; Bykov V; Kim C H; de Costa B R; Jacobson A E; Rice K C
Probing the opioid receptor complex with (+)-trans-SUPERFIT. II. Evidence that mu ligands are noncompetitive inhibitors of the delta cx opioid peptide binding site.
Peptides 1992;13(6):1137-43.
1992: Rothman R B; Bykov V; Xue B G; Xu H; De Costa B R; Jacobson A E; Rice K C; Kleinman J E; Brady L S
Interaction of opioid peptides and other drugs with multiple kappa receptors in rat and human brain. Evidence for species differences.
Peptides 1992;13(5):977-87.
1992: Rothman R B; Bykov V; Jacobson A E; Rice K C; Long J E; Bowen W D
A study of the effect of the irreversible delta receptor antagonist [D-Ala2,Leu5,Cys6]-enkephalin on delta cx and delta ncx opioid binding sites in vitro and in vivo.
Peptides 1992;13(4):691-4.
1992: de Costa B R; Iadarola M J; Rothman R B; Berman K F; George C; Newman A H; Mahboubi A; Jacobson A E; Rice K C
Probes for narcotic receptor mediated phenomena. 18. Epimeric 6 alpha- and 6 beta-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5 alpha-epoxymorphinans as potential ligands for opioid receptor single photon emission computed tomography: synthesis, evaluation, and radiochemistry of [125I]-6 beta-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5 alpha-epoxymorphinan.
Journal of medicinal chemistry 1992;35(15):2826-35.
1992: Bowen W D; Walker J M; de Costa B R; Wu R; Tolentino P J; Finn D; Rothman R B; Rice K C
Characterization of the enantiomers of cis-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)cyclohexylamine (BD737 and BD738): novel compounds with high affinity, selectivity and biological efficacy at sigma receptors.
The Journal of pharmacology and experimental therapeutics 1992;262(1):32-40.
1992: Thurkauf A; Mattson M V; Richardson S; Mirsadeghi S; Ornstein P L; Harrison E A; Rice K C; Jacobson A E; Monn J A
Analogues of the dioxolanes dexoxadrol and etoxadrol as potential phencyclidine-like agents. Synthesis and structure-activity relationships.
Journal of medicinal chemistry 1992;35(8):1323-9.
1992: Akunne H C; Johannessen J N; de Costa B R; Rice K C; Rothman R B
MPTP lesions of the nigrostriatal dopaminergic projection decrease [3H]1-[1-(2-thienyl)cyclohexyl]piperidine binding to PCP site 2: further evidence that PCP site 2 is associated with the biogenic amine reuptake complex.
Neurochemical research 1992;17(3):261-4.
1992: Jacobson A E; Linders J T; Rice K C; Monn J A; Mattson M V; George C
Three generations of electrophilic affinity ligands for the phencyclidine binding sites.
NIDA research monograph 1992;119():81-5.
1992: Newman A H; Rice K C; Jacobson A E
Potent analgesia, respiratory depression, dependence, abuse liability-clue to separability.
NIDA research monograph 1992;119():54-8.
1992: Jacobson A E; Rice K C
The continuing interrelationship of CPDD and NIDDK.
NIDA research monograph 1992;119():49-53.
1992: Rice K C
Opiate total synthesis and contemporary NIDDK analgesic research-natural and unnatural ligands for computed tomography imaging of receptors in conscious humans. Implications for future advances in the neurosciences.
NIDA research monograph 1992;119():91-5.
1992: de Costa B; Rothman R B; Bowen W D; Radesca L; Band L; Reid A; Paolo L D; Walker J M; Jacobson A E; Rice K C
Novel kappa opioid receptor and sigma ligands.
NIDA research monograph 1992;119():76-80.
1991: Rogawski M A; Yamaguchi S; Jones S M; Rice K C; Thurkauf A; Monn J A
Anticonvulsant activity of the low-affinity uncompetitive N-methyl-D- aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine (ADCI): comparison with the structural analogs dizocilpine (MK-801) and carbamazepine.
The Journal of pharmacology and experimental therapeutics 1991;259(1):30-7.
1991: Rothman R B; Mele A; Reid A A; Akunne H C; Greig N; Thurkauf A; de Costa B R; Rice K C; Pert A
GBR12909 antagonizes the ability of cocaine to elevate extracellular levels of dopamine.
Pharmacology, biochemistry, and behavior 1991;40(2):387-97.
1991: Akunne H C; Reid A A; Thurkauf A; Jacobson A E; de Costa B R; Rice K C; Heyes M P; Rothman R B
[3H]1-[2-(2-thienyl)cyclohexyl]piperidine labels two high-affinity binding sites in human cortex: further evidence for phencyclidine binding sites associated with the biogenic amine reuptake complex.
Synapse (New York, N.Y.) 1991;8(4):289-300.
1991: Ferrarese C; Guidotti A; Costa E; Miletich R S; Rice K C; de Costa B R; Fulham M J; Di Chiro G
In vivo study of NMDA-sensitive glutamate receptor by fluorothienylcyclohexylpiperidine [correction of fluorothienylcycloexylpiperidine], a possible ligand for positron emission tomography.
Neuropharmacology 1991;30(8):899-905.
1991: Kawai R; Carson R E; Dunn B; Newman A H; Rice K C; Blasberg R G
Regional brain measurement of Bmax and KD with the opiate antagonist cyclofoxy: equilibrium studies in the conscious rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1991;11(4):529-44.
1991: Rothman R B; Bykov V; Mahboubi A; Long J B; Jiang Q; Porreca F; de Costa B R; Jacobson A E; Rice K C; Holaday J W
Interaction of beta-funaltrexamine with [3H]cycloFOXY binding in rat brain: further evidence that beta-FNA alkylates the opioid receptor complex.
Synapse (New York, N.Y.) 1991;8(2):86-99.
1991: Horan P; de Costa B R; Rice K C; Porreca F
Differential antagonism of U69,593- and bremazocine-induced antinociception by (-)-UPHIT: evidence of kappa opioid receptor multiplicity in mice.
The Journal of pharmacology and experimental therapeutics 1991;257(3):1154-61.
1991: de Costa B R; Lewin A H; Rice K C; Skolnick P; Schoenheimer J A
Novel site-directed affinity ligands for GABA-gated chloride channels: synthesis, characterization, and molecular modeling of 1-(isothiocyanatophenyl)-4-tert-butyl-2,6,7-trioxabicyclo[2.2.2]octanes .
Journal of medicinal chemistry 1991;34(5):1531-8.
1991: Xu H; Kim C H; Zhu Y C; Weber R J; Jacobson A E; Rice K C; Rothman R B
(+)-cis-3-methylfentanyl and its analogs bind pseudoirreversibly to the mu opioid binding site: evidence for pseudoallosteric modulation.
Neuropharmacology 1991;30(5):455-62.
1991: Berger S P; Martenson R E; Laing P; Thurkauf A; Decosta B; Rice K C; Paul S M
Photoaffinity labeling of the dopamine reuptake carrier protein with 3-azido[3H]GBR-12935.
Molecular pharmacology 1991;39(4):429-35.
1991: Contreras P C; Ragan D M; Bremer M E; Lanthorn T H; Gray N M; Iyengar S; Jacobson A E; Rice K C; de Costa B R
Evaluation of U-50,488H analogs for neuroprotective activity in the gerbil.
Brain research 1991;546(1):79-82.
1991: Rothman R B; Mahboubi A; Bykov V; Kim C H; Jacobson A E; Rice K C
Probing the opioid receptor complex with (+)-trans-superfit. I. Evidence that [D-Pen2,D-Pen5]enkephalin interacts with high affinity at the delta cx binding site.
Peptides 1991;12(2):359-64.
1991: Witkin J M; Johnson R E; Jaffe J H; Goldberg S R; Grayson N A; Rice K C; Katz J L
The partial opioid agonist, buprenorphine, protects against lethal effects of cocaine.
Drug and alcohol dependence 1991;27(2):177-84.
1991: Herkenham M; Lynn A B; Johnson M R; Melvin L S; de Costa B R; Rice K C
Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(2):563-83.
1991: Rothman R B; Reid A; Mahboubi A; Kim C H; De Costa B R; Jacobson A E; Rice K C
Labeling by [3H]1,3-di(2-tolyl)guanidine of two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by sigma ligands.
Molecular pharmacology 1991;39(2):222-32.
1991: Moody E J; Lewin A H; de Costa B R; Rice K C; Skolnick P
Site-specific acylation of GABA-gated Cl- channels: effects on 36Cl- uptake.
European journal of pharmacology 1991;206(2):113-8.
1991: Rothman R B; Long J B; Bykov V; Xu H; Jacobson A E; Rice K C; Holaday J W
Upregulation of the opioid receptor complex by the chronic administration of morphine: a biochemical marker related to the development of tolerance and dependence.
Peptides 1991;12(1):151-60.
1991: Xu H; Ni Q; Jacobson A E; Rice K C; Rothman R B
Preliminary ligand binding data for subtypes of the delta opioid receptor in rat brain membranes.
Life sciences 1991;49(18):PL141-6.
1991: Rothman R B; Xu H; Seggel M; Jacobson A E; Rice K C; Brine G A; Carroll F I
RTI-4614-4: an analog of (+)-cis-3-methylfentanyl with a 27,000-fold binding selectivity for mu versus delta opioid binding sites.
Life sciences 1991;48(23):PL111-6.
1990: Walker J M; Bowen W D; Walker F O; Matsumoto R R; De Costa B; Rice K C
Sigma receptors: biology and function.
Pharmacological reviews 1990;42(4):355-402.
1990: Kawai R; Sawada Y; Channing M; Dunn B; Newman A H; Rice K C; Blasberg R G
Kinetic analysis of the opiate antagonist cyclofoxy in rat brain: simultaneous infusion of active and inactive enantiomers.
The Journal of pharmacology and experimental therapeutics 1990;255(2):826-35.
1990: de Costa B R; Rice K C; Bowen W D; Thurkauf A; Rothman R B; Band L; Jacobson A E; Radesca L; Contreras P C; Gray N M
Synthesis and evaluation of N-substituted cis-N-methyl-2-(1-pyrrolidinyl)cyclohexylamines as high affinity sigma receptor ligands. Identification of a new class of highly potent and selective sigma receptor probes.
Journal of medicinal chemistry 1990;33(11):3100-10.
1990: Reid A A; Kim C H; Thurkauf A; Monn J A; de Costa B; Jacobson A E; Rice K C; Bowen W D; Rothman R B
Wash-resistant inhibition of phencyclidine- and haloperidol-sensitive sigma receptor sites in guinea pig brain by putative affinity ligands: determination of selectivity.
Neuropharmacology 1990;29(11):1047-53.
1990: Kawai R; Sawada Y; Channing M; Newman A H; Rice K C; Blasberg R G
BBB transport and rapid tissue binding of cyclofoxy: comparison of active and inactive enantiomers.
The American journal of physiology 1990;259(4 Pt 2):H1278-87.
1990: Reid A A; Mattson M V; de Costa B R; Thurkauf A; Jacobson A E; Monn J A; Rice K C; Rothman R B
Specificity of phencyclidine-like drugs and benzomorphan opiates for two high affinity phencyclidine binding sites in guinea pig brain.
Neuropharmacology 1990;29(9):811-7.
1990: Rothman R B; Long J B; Bykov V; Jacobson A E; Rice K C; Holaday J W
Pretreatment of rats with the irreversible mu-receptor antagonist, beta-FNA, fails to prevent naltrexone-induced upregulation of mu-opioid receptors.
Neuropharmacology 1990;29(9):805-10.
1990: Thurkauf A; de Costa B; Mattson M V; France C P; Price M T; Olney J W; Woods J H; Jacobson A E; Rice K C
Synthesis, phencyclidine-like pharmacology, and antiischemic potential of meta-substituted 1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridines.
Journal of medicinal chemistry 1990;33(8):2211-5.
1990: McCabe R T; de Costa B R; Miller R L; Havunjian R H; Rice K C; Skolnick P
Characterization of benzodiazepine receptors with fluorescent ligands.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(11):2934-40.
1990: Rice K C; Bolger G T
Interactions between phencyclidine and nifedipine at 45Ca2(+)-uptake sites on mouse brain neurons.
Biochemical pharmacology 1990;39(11):1825-7.
1990: Thurkauf A; de Costa B; Yamaguchi S; Mattson M V; Jacobson A E; Rice K C; Rogawski M A
Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues.
Journal of medicinal chemistry 1990;33(5):1452-8.
1990: Matsumoto R R; Hemstreet M K; Lai N L; Thurkauf A; De Costa B R; Rice K C; Hellewell S B; Bowen W D; Walker J M
Drug specificity of pharmacological dystonia.
Pharmacology, biochemistry, and behavior 1990;36(1):151-5.
1990: Creveling C R; Bell M E; Burke T R; Chang E; Lewandowski-Lovenberg G A; Kim C H; Rice K C; Daly J W
Procaine isothiocyanate: an irreversible inhibitor of the specific binding of [3H]batrachotoxinin-A benzoate to sodium channels.
Neurochemical research 1990;15(4):441-8.
1990: de Costa B R; Rothman R B; Bykov V; Band L; Pert A; Jacobson A E; Rice K C
Probes for narcotic receptor mediated phenomena. 17. Synthesis and evaluation of a series of trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacet amide (U50,488) related isothiocyanate derivatives as opioid receptor affinity ligands.
Journal of medicinal chemistry 1990;33(4):1171-6.
1990: Herkenham M; Lynn A B; Little M D; Johnson M R; Melvin L S; de Costa B R; Rice K C
Cannabinoid receptor localization in brain.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(5):1932-6.
1990: Rothman R B; Bykov V; de Costa B R; Jacobson A E; Rice K C; Brady L S
Interaction of endogenous opioid peptides and other drugs with four kappa opioid binding sites in guinea pig brain.
Peptides 1990;11(2):311-31.
1990: Monn J A; Thurkauf A; Mattson M V; Jacobson A E; Rice K C
Synthesis and structure-activity relationship of C5-substituted analogues of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine [(+-)-desmethyl-MK801]: ligands for the NMDA receptor-coupled phencyclidine binding site.
Journal of medicinal chemistry 1990;33(3):1069-76.
1990: Nabeshima T; Yoshida S; Morinaka H; Kameyama T; Thurkauf A; Rice K C; Jacobson A E; Monn J A; Cho A K
MK-801 ameliorates delayed amnesia, but potentiates acute amnesia induced by CO.
Neuroscience letters 1990;108(3):321-7.
1990: Band L; Xu H; Bykov V; Greig N; Kim C H; Newman A; Jacobson A E; Rice K C; Rothman R B
The potent opioid agonist, (+)-cis-3-methylfentanyl binds pseudoirreversibly to the opioid receptor complex in vitro and in vivo: evidence for a novel mechanism of action.
Life sciences 1990;47(24):2231-40.
1990: Reid A A; Monn J A; Jacobson A E; Rice K C; Rothman R B
Pseudoallosteric modulation by (+)-MK801 of NMDA-coupled phencyclidine binding sites.
Life sciences 1990;47(16):PL77-82.
1990: Rothman R B; Bykov V; de Costa B R; Jacobson A E; Rice K C; Brady L S
Evidence for four opioid kappa binding sites in guinea pig brain.
Progress in clinical and biological research 1990;328():9-12.
1990: Walker J M; Patrick S L; Thurkauf A; Rice K C; Bowen W D
Inhibition of cholinergic analgesia by (+)-opiates.
Progress in clinical and biological research 1990;328():81-4.
1990: Band L; de Costa B R; Bykov V; Pert A; Rice K C; Rothman R B
The affinity ligand "UPHIT" acylates kappa opioid binding sites in vivo.
Progress in clinical and biological research 1990;328():77-80.
1990: Bowen W D; DeCosta B; Hellewell S B; Thurkauf A; Walker J M; Rice K C
Characterization of [3H] (+)-pentazocine, a highly selective sigma ligand.
Progress in clinical and biological research 1990;328():117-20.
1990: Williams W; Rice K C; Weber R J
Nonpeptide opioids: in vivo effects on the immune system.
NIDA research monograph 1990;105():404-7.
1990: Rice K C; Cook J M
In memoriam: Ulrich Weiss 1908-1989.
NIDA research monograph 1990;105():130-2.
1990: Akunne H; deCosta B R; Rice K C; Jacobson A E; Rothman R B
Evidence for high and low affinity [3H]cocaine binding sites associated with the serotonin reuptake complex in guinea pig brain: allosteric modulation by paroxetine.
NIDA research monograph 1990;105():547-8.
1990: Rothman R B; Mele A; Reid A A; Akunne H; Grieg N; Thurkauf A; deCosta B R; Rice K C; Pert A
Preliminary evidence that the high affinity dopamine reuptake inhibitor, GBR12909, antagonizes the ability of cocaine to elevate extracellular levels of dopamine.
NIDA research monograph 1990;105():359-60.
1990: deCosta B R; Rothman R R; Akunne H; Jacobson A E; Rice K C
Synthesis and evaluation of novel BTCP based affinity ligands for the dopamine reuptake complex.
NIDA research monograph 1990;105():437-8.
1990: Weber R J; Band L C; deCosta B; Pert A; Rice K C
Neural control of immune function: opioids, opioid receptors and immunosuppression.
NIDA research monograph 1990;105():96-102.
1990: Radesca L A; deCosta B R; Bowen W D; DiPaolo L J; Rice K C
Identification of a novel class of highly potent sigma ligands related to the kappa-selective agonist U50,488.
NIDA research monograph 1990;105():518-9.
1990: Xu H; Kim C H; Zhu Y C; Weber R J; Rice K C; Rothman R B
Pseudoirreversible binding of opiates to opioid receptor subtypes in rat brain: a quantitative study.
NIDA research monograph 1990;105():410-1.
1990: Linders J T; Burke T R; Jacobson A E; Rice K C
Oxide-bridged 5-phenylmorphans as probes for narcotic receptor mediated phenomena.
NIDA research monograph 1990;105():388-9.
1990: Jiang Q; Rice K C; deCosta B; Porreca F
Effects of oxymorphindole on morphine induced-antinociception in mice and rats.
NIDA research monograph 1990;105():384-5.
1990: Grayson N A; Rothman R B; Xu H; Rice K C
Pharmacological properties of (+)-buprenorphine and (+)-diprenorphine.
NIDA research monograph 1990;105():380-1.
1990: Rothman R B; Mahboubi A; Reid A A; Kim C H; deCosta B R; Jacobson A E; Rice K C
[3H]1,3-Di(2-tolyl)guanidine labels two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel blockers and sigma ligands.
NIDA research monograph 1990;105():335-6.
1989: Benkelfat C; Aulakh C S; Bykov V; Rice K C; De Costa B R; Rothman R B
Apparent down-regulation of rat brain mu- and kappa-opioid binding sites labelled with [3H]cycloFOXY following chronic administration of the potent 5-hydroxytryptamine reuptake blocker, clomipramine.
The Journal of pharmacy and pharmacology 1989;41(12):865-7.
1989: Rothman R B; Long J B; Holaday J W; Bykov V; de Costa B R; Kim C H; Jacobson A E; Rice K C
A study of the interaction of the alkylating agent, NIH10236, with opioid receptors in vitro and in vivo.
Neuropharmacology 1989;28(12):1349-56.
1989: Rothman R B; Reid A A; Monn J A; Jacobson A E; Rice K C
The psychotomimetic drug phencyclidine labels two high affinity binding sites in guinea pig brain: evidence for N-methyl-D-aspartate-coupled and dopamine reuptake carrier-associated phencyclidine binding sites.
Molecular pharmacology 1989;36(6):887-96.
1989: Rothman R B; Mele A; Reid A A; Akunne H; Greig N; Thurkauf A; Rice K C; Pert A
Tight binding dopamine reuptake inhibitors as cocaine antagonists. A strategy for drug development.
FEBS letters 1989;257(2):341-4.
1989: Rothman R B; France C P; Bykov V; De Costa B R; Jacobson A E; Woods J H; Rice K C
Pharmacological activities of optically pure enantiomers of the kappa opioid agonist, U50,488, and its cis diastereomer: evidence for three kappa receptor subtypes.
European journal of pharmacology 1989;167(3):345-53.
1989: de Costa B R; Bowen W D; Hellewell S B; George C; Rothman R B; Reid A A; Walker J M; Jacobson A E; Rice K C
Alterations in the stereochemistry of the kappa-selective opioid agonist U50,488 result in high-affinity sigma ligands.
Journal of medicinal chemistry 1989;32(8):1996-2002.
1989: de Costa B R; Bowen W D; Hellewell S B; Walker J M; Thurkauf A; Jacobson A E; Rice K C
Synthesis and evaluation of optically pure [3H]-(+)-pentazocine, a highly potent and selective radioligand for sigma receptors.
FEBS letters 1989;251(1-2):53-8.
1989: Nabeshima T; Tohyama K; Noda A; Maeda Y; Hiramatsu M; Harrer S M; Kameyama T; Furukawa H; Jacobson A E; Rice K C
Effects of metaphit on phencyclidine and serotonin2 receptors.
Neuroscience letters 1989;102(2-3):303-8.
1989: Rogawski M A; Thurkauf A; Yamaguchi S; Rice K C; Jacobson A E; Mattson M V
Anticonvulsant activities of 1-phenylcyclohexylamine and its conformationally restricted analog 1,1-pentamethylenetetrahydroisoquinoline.
The Journal of pharmacology and experimental therapeutics 1989;249(3):708-12.
1989: de Costa B R; Band L; Rothman R B; Jacobson A E; Bykov V; Pert A; Rice K C
Synthesis of an affinity ligand ('UPHIT') for in vivo acylation of the kappa-opioid receptor.
FEBS letters 1989;249(2):178-82.
1989: Kim C H; Rothman R B; Jacobson A E; Mattson M V; Bykov V; Streaty R A; Klee W A; George C; Long J B; Rice K C
Probes for narcotic receptor mediated phenomena. 15. (3S,4S)-(+)-trans-3-methylfentanyl isothiocyanate, a potent site-directed acylating agent for the delta opioid receptors in vitro.
Journal of medicinal chemistry 1989;32(6):1392-8.
1989: Bluth L S; Rice K C; Jacobson A E; Bowen W D
Acylation of sigma receptors by Metaphit, an isothiocyanate derivative of phencyclidine.
European journal of pharmacology 1989;161(2-3):273-7.
1989: McCabe R T; Schoenheimer J A; Skolnick P; Newman A H; Rice K C; Reig J A; Klein D C
[3H]AHN 086 acylates peripheral benzodiazepine receptors in the rat pineal gland.
FEBS letters 1989;244(2):263-7.
1989: Lewin A H; de Costa B R; Rice K C; Skolnick P
meta- and para-isothiocyanato-t-butylbicycloorthobenzoate: irreversible ligands of the gamma-aminobutyric acid-regulated chloride ionophore.
Molecular pharmacology 1989;35(2):189-94.
1989: Bolger G T; Newman A H; Rice K C; Lueddens H W; Basile A S; Skolnick P
Characterization of the effects of AHN 086, an irreversible ligand of "peripheral" benzodiazepine receptors, on contraction in guinea-pig atrial and ileal longitudinal smooth muscle.
Canadian journal of physiology and pharmacology 1989;67(2):126-34.
1989: Rothman R B; Bykov V; Long J B; Brady L S; Jacobson A E; Rice K C; Holaday J W
Chronic administration of morphine and naltrexone up-regulate mu-opioid binding sites labeled by [3H][D-Ala2,MePhe4,Gly-ol5]enkephalin: further evidence for two mu-binding sites.
European journal of pharmacology 1989;160(1):71-82.
1989: Moody E J; Mattson M; Newman A H; Rice K C; Skolnick P
Stereospecific reversal of nitrous oxide analgesia by naloxone.
Life sciences 1989;44(11):703-9.
1989: Skolnick P; Marvizón J C; Jackson B W; Monn J A; Rice K C; Lewin A H
Blockade of N-methyl-D-aspartate induced convulsions by 1-aminocyclopropanecarboxylates.
Life sciences 1989;45(18):1647-55.
1989: Richardson S; Herkenham M; Mirsadeghi S; Johnson M R; Melvin L S; Rice K C
Progress toward the synthesis of potential affinity ligands for the analgesic cannabinoid receptor based on CP-55,244.
NIDA research monograph 1989;95():532-3.
1989: Band L; Bykov V; Greig N; Kim C H; Hauck-Newman A; Jacobson A E; Rice K C; Rothman R B
In vivo binding of (+)-cis methylfentanyl at the opiate receptor complex and behavioral correlates: evidence for a novel mechanism of action.
NIDA research monograph 1989;95():554-5.
1989: Reid A A; Monn J A; Jacobson A E; Rice K C; Rothman R B
Characterization of NMDA-coupled and dopamine reuptake carrier coupled [3H]-TCP binding sites in guinea pig brain.
NIDA research monograph 1989;95():530-1.
1989: Thurkauf A; Monn J; Mattson M V; Jacobson A E; Rice K C
Structural and conformational aspects of the binding of aryl-alkyl amines to the phencyclidine binding site.
NIDA research monograph 1989;95():51-6.
1989: Newman A H; McCabe R T; Schoenheimer J A; Skolnick P; Rice K C; Reig J A; Klein D C
[3H]AHN 086 acylates peripheral benzodiazepine receptors in the rat pineal gland.
NIDA research monograph 1989;95():285-6.
1988: Rothman R B; Bykov V; Reid A; De Costa B R; Newman A H; Jacobson A E; Rice K C
A brief study of the selectivity of norbinaltorphimine, (-)-cyclofoxy, and (+)-cyclofoxy among opioid receptor subtypes in vitro.
Neuropeptides 1988;12(3):181-7.
1988: Rothman R B; Bykov V; Newman A H; Jacobson A E; Rice K C
Interaction of enantiomeric pairs of opiates with phencyclidine binding sites in rat brain: identification of (+) pentazocine as a ligand potentially suitable for imaging sigma binding sites using positron emission tomography.
Neuropeptides 1988;12(1):1-5.
1988: Bolger G T; Skolnick P; Rice K C; Weissman B A
Differential regulation of mu-opiate receptors in heroin- and morphine-dependent rats.
FEBS letters 1988;234(1):22-6.
1988: Bowen W D; Kirschner B N; Newman A H; Rice K C
Sigma receptors negatively modulate agonist-stimulated phosphoinositide metabolism in rat brain.
European journal of pharmacology 1988;149(3):399-400.
1988: Bowen W D; Rodrigues P A; Wanzor T E; Jacobson A E; Rice K C
Differential coupling of mu-competitive and mu-noncompetitive delta opiate receptors to guanine nucleotide binding proteins in rat brain membranes.
Biochemical pharmacology 1988;37(3):467-72.
1988: Rothman R B; Bykov V; Ofri D; Rice K C
LY164929: a highly selective ligand for the lower affinity [3H]D-Ala2-D-Leu-5-enkephalin binding site.
Neuropeptides 1988;11(1):13-6.
1988: Rothman R B; Bykov V; Rice K C; Jacobson A E; Kooper G N; Bowen W D
Tritiated-6-beta-fluoro-6-desoxy-oxymorphone ([3H]FOXY): a new ligand and photoaffinity probe for the mu opioid receptors.
Neuropeptides 1988;11(1):1-6.
1987: Jacobson A E; Harrison E A; Mattson M V; Rafferty M F; Rice K C; Woods J H; Winger G; Solomon R E; Lessor R A; Silverton J V
Enantiomeric and diastereomeric dioxadrols: behavioral, biochemical and chemical determination of the configuration necessary for phencyclidine-like properties.
The Journal of pharmacology and experimental therapeutics 1987;243(1):110-7.
1987: Newman A H; Lueddens H W; Skolnick P; Rice K C
Novel irreversible ligands specific for "peripheral" type benzodiazepine receptors: (+/-)-, (+)-, and (-)-1-(2-chlorophenyl)-N-(1-methylpropyl)-N- (2-isothiocyanatoethyl)-3-isoquinolinecarboxamide and 1-(2-isothiocyanatoethyl)-7-chloro-1,3-dihydro-5-(4-chlorophenyl )-2H-1,4-benzodiazepin-2-one.
Journal of medicinal chemistry 1987;30(10):1901-5.
1987: Awaya H; May E L; Aceto M D; Harris L S; Silverton J V; Rice K C; Mattson M V; Jacobson A E
Hexahydro-1H-1-pyrindines from acid rearrangement of 9-alkylidene-5-(m-methoxyphenyl)-2-methylmorphans. A new structural type of narcotic antagonists.
Journal of medicinal chemistry 1987;30(5):947-50.
1987: Newman A H; Lueddens H W; Skolnick P; Rice K C
Synthesis and biochemical characterization of two novel irreversible ligands specific for "peripheral" benzodiazepine receptors.
NIDA research monograph 1987;76():356-62.
1986: Contreras P C; Johnson S; Freedman R; Hoffer B; Olsen K; Rafferty M F; Lessor R A; Rice K C; Jacobson A E; O'Donohue T L
Metaphit, an acylating ligand for phencyclidine receptors: characterization of in vivo actions in the rat.
The Journal of pharmacology and experimental therapeutics 1986;238(3):1101-7.
1986: Lueddens H W; Newman A H; Rice K C; Skolnick P
AHN 086: an irreversible ligand of "peripheral" benzodiazepine receptors.
Molecular pharmacology 1986;29(6):540-5.
1986: Wang Y; Pang K; Jacobson A E; Lessor R; Rice K C; Hoffer B
Interactions of phencyclidine with hippocampal circuitry: evidence for neuronal heterogeneity.
Pharmacology, biochemistry, and behavior 1986;24(5):1403-7.
1986: Koek W; Woods J H; Jacobson A E; Rice K C; Lessor R A
Metaphit, a proposed phencyclidine receptor acylator: phencyclidine-like behavioral effects and evidence of absence of antagonist activity in pigeons and in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1986;237(2):386-92.
1986: Wang Y; Palmer M; Freedman R; Hoffer B; Mattson M V; Lessor R A; Rice K C; Jacobson A E
Antagonism of phencyclidine action by metaphit in rat cerebellar Purkinje neurons: an electrophysiological study.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2724-7.
1986: Lessor R A; Mattson M V; Rice K C; Jacobson A E
Electrophilic affinity ligands for the phencyclidine (PCP) receptor.
NIDA research monograph 1986;67():138-44.
1985: Koek W; Head R; Holsztynska E J; Woods J H; Domino E F; Jacobson A E; Rafferty M F; Rice K C; Lessor R A
Effects of metaphit, a proposed phencyclidine receptor acylator, on catalepsy in pigeons.
The Journal of pharmacology and experimental therapeutics 1985;234(3):648-53.
1985: Contreras P C; Rafferty M F; Lessor R A; Rice K C; Jacobson A E; O'Donohue T L
A specific alkylating ligand for phencyclidine (PCP) receptors antagonizes PCP behavioral effects.
European journal of pharmacology 1985;111(3):405-6.
1984: Harrison E A; Rafferty M F; Rice K C; Creveling C R; Winger G D; Woods J H; Jacobson A E
Evidence for separation of anesthetic activity from prototypic phencyclidine action in drug discrimination by molecular modification of dioxadrol, a phencyclidine-like dissociative anesthetic.
NIDA research monograph 1984;55():90-6.

Sign-in to see more