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Paul Ridker

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Paul M Ridker; Jacques Genest; John J P Kastelein; Wolfgang Koenig
C-reactive protein and cholesterol are equally strong predictors of cardiovascular risk and both are important for quality clinical care.
Audrey Y Chu; Gary C Curhan; Franco Giulianini; Frank B Hu; David J Hunter; Julius S Ngwa; Louis R Pasquale; Nina P Paynter; Lu Qi; Qibin Qi; Paul M Ridker; Eric B Rimm; Lynda M Rose; Toshiko Tanaka; Tsegaselassie Workalemahu; Daniel I Chasman
Novel locus including FGF21 is associated with dietary macronutrient intake.
Vinod P Mitta; Paul M Ridker; Eric B Rimm; William G Christen; Robert J Glynn; Susan E Hankinson; Richard D Semba; Debra A Schaumberg
C-reactive protein and the incidence of macular degeneration: pooled analysis of 5 cohorts.

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All Publications

2013: Paul M Ridker; Jacques Genest; John J P Kastelein; Wolfgang Koenig
C-reactive protein and cholesterol are equally strong predictors of cardiovascular risk and both are important for quality clinical care.
European heart journal 2013;34(17):1258-61.
2013: Audrey Y Chu; Gary C Curhan; Franco Giulianini; Frank B Hu; David J Hunter; Julius S Ngwa; Louis R Pasquale; Nina P Paynter; Lu Qi; Qibin Qi; Paul M Ridker; Eric B Rimm; Lynda M Rose; Toshiko Tanaka; Tsegaselassie Workalemahu; Daniel I Chasman
Novel locus including FGF21 is associated with dietary macronutrient intake.
Human molecular genetics 2013;22(9):1895-902.
2013: Vinod P Mitta; Paul M Ridker; Eric B Rimm; William G Christen; Robert J Glynn; Susan E Hankinson; Richard D Semba; Debra A Schaumberg
C-reactive protein and the incidence of macular degeneration: pooled analysis of 5 cohorts.
JAMA ophthalmology 2013;131(4):507-13.
2013: Robert Y L Zee; Lynda Rose; Daniel I Chasman; Paul M Ridker
Genetic variation of fifteen folate metabolic pathway associated gene loci and the risk of incident head and neck carcinoma: the Women's Genome Health Study.
Clinica chimica acta; international journal of clinical chemistry 2013;418():33-6.
2013: Brendan M Everett; Maria C Magnone; Maria Bobadilla; Daniel I Chasman; Nancy R Cook; Paul M Ridker; Nader Rifai; Aruna D Pradhan
Prospective evaluation of B-type natriuretic peptide concentrations and the risk of type 2 diabetes in women.
Clinical chemistry 2013;59(3):557-65.
2013: Paul M Ridker; Nader Rifai
Expanding options for scientific publication: is more always better?
Circulation 2013;127(2):155-6.
2013: Paul M Ridker
Moving beyond JUPITER: will inhibiting inflammation reduce vascular event rates?
Current atherosclerosis reports 2013;15(1):295.
2013: J S Danik; J E Buring; Daniel I Chasman; Paul M Ridker; R Y L Zee; R J Glynn
Lipoprotein(a), polymorphisms in the LPA gene, and incident venous thromboembolism among 21483 women.
Journal of thrombosis and haemostasis : JTH 2013;11(1):205-8.
2012: Paul M Ridker; Tom Thuren; Verena Walter; Brendan Everett; Johannes Hensen; Campbell P Howard; Peter Libby
Effects of interleukin-1β inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: a phase IIb randomized, placebo-controlled trial.
Circulation 2012;126(23):2739-48.
2012: Audrey Y Chu; Josée Dupuis; Harald Grallert; Franco Guilianini; Fredrik Nyberg; Christie M Ballantyne; Bryan J Barratt; Daniel I Chasman; Paul M Ridker
Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.
Circulation. Cardiovascular genetics 2012;5(6):676-85.
2012: Subodh Verma; Milan Gupta; Paul M Ridker
Therapeutic targeting of inflammation in atherosclerosis: we are getting closer.
The Canadian journal of cardiology 2012;28(6):619-22.
2012: Qibin Qi; Paul M Ridker; Eric B Rimm; Walter C Willett; Daniel I Chasman; Audrey Y Chu; Gary C Curhan; Frank B Hu; David J Hunter; Majken K Jensen; Jae H Kang; Louis R Pasquale; Lu Qi
Sugar-sweetened beverages and genetic risk of obesity.
The New England journal of medicine 2012;367(15):1387-96.
2012: Stacey L Eggert; Andrew C Heath; Karen L Huyck; Raghava Kavalla; Ake T Lu; Pamela A F Madden; Nicholas G Martin; Sarah E Medland; Grant W Montgomery; Dale R Nyholt; Jodie N Painter; Paul M Ridker; Lynda Rose; Priya Somasundaram; Elizabeth A Stewart; Susan A Treloar; Krina T Zondervan; Julie E Buring; Rita M Cantor; Daniel I Chasman; Cynthia C Morton
Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata.
American journal of human genetics 2012;91(4):621-8.
2012: Lu Wang; Barbara Cochrane; Nancy R Cook; J Michael Gaziano; Simin Liu; JoAnn E Manson; Paul M Ridker; Nader Rifai; Howard D Sesso
Plasma adiponectin and the risk of hypertension in white and black postmenopausal women.
Clinical chemistry 2012;58(10):1438-45.
2012: Nancy R Cook; JoAnn E Manson; Lisa W Martin; Nina P Paynter; Jennifer G Robinson; Sylvia Wassertheil-Smoller; Paul M Ridker
Clinical utility of lipoprotein-associated phospholipase A₂ for cardiovascular disease prediction in a multiethnic cohort of women.
Clinical chemistry 2012;58(9):1352-63.
2012: David Preiss; Paul M Ridker; Naveed Sattar; Matti J Tikkanen; Paul Welsh; Michael J Murphy; Terje R Pedersen; Helen M Colhoun; David A DeMicco; Marshall B Elam; Ian Ford; Ilan Goldenberg; Anthony C Keech; John Kjekshus; John C LaRosa; Laura C Lovato; Thomas M MacDonald; John J V McMurray
Lipid-modifying therapies and risk of pancreatitis: a meta-analysis.
JAMA : the journal of the American Medical Association 2012;308(8):804-11.
2012: Paul M Ridker; Peter Libby; Jean G MacFadyen; Aruna Pradhan; Robert J Glynn
Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial.
Lancet 2012;380(9841):565-71.
2012: Hannah C Cox; Joanne Curran; Thomas D Dyer; Claire Bellis; John C Blangero; Melanie A Carless; Jac C Charlesworth; Daniel Chasman; Rod A Lea; Stuart Macgregor; Dale R Nyholt; Paul M Ridker; Markus Schürks; Lyn R Griffiths
A genome-wide analysis of 'Bounty' descendants implicates several novel variants in migraine susceptibility.
Neurogenetics 2012;13(3):261-6.
2012: Paul M Ridker
What works and in whom? A simple, easily applied, evidence-based approach to guidelines for statin therapy.
Circulation. Cardiovascular quality and outcomes 2012;5(4):592-3.
2012: I-Min Lee; Charles P Mouton; Paul M Ridker; Howard D Sesso; Marcia L Stefanick; JoAnn E Manson
Physical activity and inflammation in a multiethnic cohort of women.
Medicine and science in sports and exercise 2012;44(6):1088-96.
2012: Paul M Ridker; Robert L Wolfert; Jean G MacFadyen; Wolfgang Koenig
Relationship of lipoprotein-associated phospholipase A₂ mass and activity with incident vascular events among primary prevention patients allocated to placebo or to statin therapy: an analysis from the JUPITER trial.
Clinical chemistry 2012;58(5):877-86.
2012: Samia Mora; Børge G Nordestgaard; S Matthijs Boekholdt; Robert J Glynn; John J P Kastelein; Paul M Ridker
On-treatment non-high-density lipoprotein cholesterol, apolipoprotein B, triglycerides, and lipid ratios in relation to residual vascular risk after treatment with potent statin therapy: JUPITER (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin).
Journal of the American College of Cardiology 2012;59(17):1521-8.
2012: Victor Novack; Yaniv Almog; Robert J Glynn; Jean MacFadyen; Atul Malhotra; Paul M Ridker
The effect of rosuvastatin on incident pneumonia: results from the JUPITER trial.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2012;184(7):E367-72.
2012: Nancy R Cook; Charles B Eaton; JoAnn E Manson; Lisa W Martin; Nina P Paynter; Jennifer G Robinson; Jacques E Rossouw; Sylvia Wassertheil-Smoller; Paul M Ridker
Comparison of the Framingham and Reynolds Risk scores for global cardiovascular risk prediction in the multiethnic Women's Health Initiative.
Circulation 2012;125(14):1748-56, S1-11.
2012: Daniel I Chasman; Franco Giulianini; Jean MacFadyen; Fredrik Nyberg; Bryan J Barratt; Paul M Ridker
Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.
Circulation. Cardiovascular genetics 2012;5(2):257-64.
2012: S Matthijs Boekholdt; Michael B Clearfield; Helen M Colhoun; David A DeMicco; John R Downs; Paul Durrington; Antonio M Gotto; Graham A Hitman; John C LaRosa; Samia Mora; Paul J Nestel; Terje R Pedersen; Paul M Ridker; R John Simes; Andrew M Tonkin; K M A Welch; Aeilko H Zwinderman; Benoit J Arsenault; John J P Kastelein
Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis.
JAMA : the journal of the American Medical Association 2012;307(12):1302-9.
2012: Roopinder K Sandhu; David Conen; Nancy R Cook; Tobias Kurth; Paul M Ridker; Christine M Albert
Relation of renal function to risk for incident atrial fibrillation in women.
The American journal of cardiology 2012;109(4):538-42.
2012: Paul M Ridker
Hyperlipidemia as an instigator of inflammation: inaugurating new approaches to vascular prevention.
Journal of the American Heart Association 2012;1(1):3-5.
2012: Audrey Y Chu; Franco Guilianini; Fredrik Nyberg; Bryan J Barratt; Daniel I Chasman; Paul M Ridker
Pharmacogenetic determinants of statin-induced reductions in C-reactive protein.
Circulation. Cardiovascular genetics 2012;5(1):58-65.
2012: Howard D Sesso; Lu Wang; Paul M Ridker; Julie E Buring
Tomato-based food products are related to clinically modest improvements in selected coronary biomarkers in women.
The Journal of nutrition 2012;142(2):326-33.
2012: Jessica M Peña; Robert J Glynn; Jean MacFadyen; Paul M Ridker
High-sensitivity C-reactive protein, statin therapy, and risks of atrial fibrillation: an exploratory analysis of the JUPITER trial.
European heart journal 2012;33(4):531-7.
2012: K C Fitzgerald; J E Buring; S E Chiuve; Paul M Ridker; R J Glynn
Comparison of associations of adherence to a Dietary Approaches to Stop Hypertension (DASH)-style diet with risks of cardiovascular disease and venous thromboembolism.
Journal of thrombosis and haemostasis : JTH 2012;10(2):189-98.
2012: Paul M Ridker
Coronary artery calcium for guiding statin treatment.
Lancet 2012;379(9813):311-2; author reply 312-3.
2012: Paul M Ridker
Lipoprotein(a), ethnicity, and cardiovascular risk: erasing a paradox and filling a clinical gap.
Circulation 2012;125(2):207-9.
2012: Bridget H Maher; Paul M Ridker; Markus Schürks; Tobias Kurth; Rod A Lea; Claire Bellis; Miles Benton; John C Blangero; Julie E Buring; Melanie A Carless; Jac C Charlesworth; Daniel I Chasman; Hannah C Cox; Joanne E Curran; Thomas D Dyer; Lyn R Griffiths
An X chromosome association scan of the Norfolk Island genetic isolate provides evidence for a novel migraine susceptibility locus at Xq12.
PloS one 2012;7(5):e37903.
2012: Chunyan He; Albert Hofman; Julie E Buring; STEPHEN CHANOCK; Daniel I Chasman; Laura Crisponi; Ellen W Demerath; Jill Dreyfus; Lindsay Fernández-Rhodes; Nora Franceschini; Susan E Hankinson; Shih-Jen Hwang; Kathryn L Lunetta; Joanne M Murabito; Giuseppe Palmieri; Eleonora Porcu; Paul M Ridker; Fernando Rivadeneira; Lynda M Rose; Rikje Ruiter; Serena Sanna; Greta L Splansky; Lisette Stolk; Bruno H Stricker; André G Uitterlinden; David J Hunter
Reproductive aging-associated common genetic variants and the risk of breast cancer.
Breast cancer research : BCR 2012;14(2):R54.
2012: Cheryl R Clark; Brent Coull; Carrie E Huisingh; Mark J Ommerborn; Paul M Ridker; Julie E Buring; Lisa F Berkman
Cardiovascular inflammation in healthy women: multilevel associations with state-level prosperity, productivity and income inequality.
BMC public health 2012;12():211.
2011: Samia Mora; Paul M Ridker; Julie E Buring; Yadong Cui
Association of high-density lipoprotein cholesterol with incident cardiovascular events in women, by low-density lipoprotein cholesterol and apolipoprotein B100 levels: a cohort study.
Annals of internal medicine 2011;155(11):742-50.
2011: Johannes A N Dorresteijn; Nina P Paynter; Paul M Ridker; Yolanda van der Graaf; Frank L J Visseren; Annemarie M J Wassink; Julie E Buring; Nancy R Cook
Aspirin for primary prevention of vascular events in women: individualized prediction of treatment effects.
European heart journal 2011;32(23):2962-9.
2011: Stefan Kiechl; Ross C Laxton; Guillaume Paré; Lu Qi; Paul M Ridker; Russell P Tracy; Johann Willeit; Jacqueline C M Witteman; Qingzhong Xiao; Qingbo Xu; Christie M Ballantyne; Maja Barbalic; Emelia J Benjamin; Joshua C Bis; Enzo Bonora; Daniel I Chasman; Abbas Dehghan; Josée Dupuis; Shu Ye
Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis.
Circulation. Cardiovascular genetics 2011;4(6):681-6.
2011: Deborah Y Ho; Eunjung Kim; Kathryn A Britton; Nancy R Cook; Mark A Creager; Paul M Ridker; Aruna D Pradhan
High-molecular-weight and total adiponectin levels and incident symptomatic peripheral artery disease in women: a prospective investigation.
Circulation 2011;124(21):2303-11.
2011: Renata Micha; Miguel A Hernán; Fumiaki Imamura; Paul M Ridker; Daniel H Solomon; Moritz Wyler von Ballmoos; Dariush Mozaffarian
Systematic review and meta-analysis of methotrexate use and risk of cardiovascular disease.
The American journal of cardiology 2011;108(9):1362-70.
2011: Nina P Paynter; Aruna D Pradhan; Paul M Ridker; J Michael Gaziano; Norman A Mazer; Nancy R Cook
Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalent.
Archives of internal medicine 2011;171(19):1712-8.
2011: Paul M Ridker; Tom Thuren; Andrew Zalewski; Peter Libby
Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS).
American heart journal 2011;162(4):597-605.
2011: M Alan Brookhart; Robert J Glynn; Daniel H Solomon; Paul M Ridker
Effect of rosuvastatin on hemoglobin levels in patients with anemia and low-grade inflammation: a post hoc analysis of the JUPITER trial.
Journal of clinical pharmacology 2011;51(10):1483-7.
2011: Robert Y L Zee; Paul M Ridker; Daniel I Chasman
Genetic variants of 11 telomere-pathway gene loci and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.
Atherosclerosis 2011;218(1):144-6.
2011: Paul M Ridker
A tale of three labels: translating the JUPITER trial data into regulatory claims.
Clinical trials (London, England) 2011;8(4):417-22.
2011: Andrew T Chan; Ernest T Hawk; Paul M Ridker; Camelia S Sima; Ann G Zauber; Monica M Bertagnolli
C-reactive protein and risk of colorectal adenoma according to celecoxib treatment.
Cancer prevention research (Philadelphia, Pa.) 2011;4(8):1172-80.
2011: Tiffany M Powell; Julie E Buring; Mark A Creager; Robert J Glynn; Paul M Ridker; Aruna D Pradhan
The relative importance of systolic versus diastolic blood pressure control and incident symptomatic peripheral artery disease in women.
Vascular medicine (London, England) 2011;16(4):239-46.
2011: Michelle A Albert; Keith C Ferdinand; Francisco A H Fonseca; Robert J Glynn; Alberto J Lorenzatti; Jean G MacFadyen; Paul M Ridker
Race, ethnicity, and the efficacy of rosuvastatin in primary prevention: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.
American heart journal 2011;162(1):106-14.e2.
2011: Daniel I Chasman; Boukje De Vries; Florian Ernst; Konstanze Fendrich; Michel D Ferrari; Tobias Freilinger; Lyn R Griffiths; Wolfgang Hoffmann; Mikko Kallela; Christian Kubisch; Lenore J Launer; Aarno Palotie; Paul M Ridker; Ulf Schminke; Markus Schürks; Gisela M Terwindt; Arn M J M van den Maagdenberg; Henry Völzke; Robert Y L Zee; Verneri Anttila; Julie E Buring; Tobias Kurth
Genome-wide association study reveals three susceptibility loci for common migraine in the general population.
Nature genetics 2011;43(7):695-8.
2011: Eugene Braunwald; Marc A Pfeffer; Frank M Sacks; Paul M Ridker
HMG CoA reduction in patients with average cholesterol concentrations.
Clinical chemistry 2011;57(7):1072-3.
2011: Brendan M Everett; Eunjung Kim; Maria C Magnone; Maria Bobadilla; Nancy R Cook; Paul M Ridker; Nader Rifai; Aruna D Pradhan
Sensitive cardiac troponin T assay and the risk of incident cardiovascular disease in women with and without diabetes mellitus: the Women's Health Study.
Circulation 2011;123(24):2811-8.
2011: David Conen; Mark A Creager; Brendan M Everett; Tobias Kurth; Julie E Buring; Paul M Ridker; Aruna D Pradhan
Smoking, smoking cessation, [corrected] and risk for symptomatic peripheral artery disease in women: a cohort study.
Annals of internal medicine 2011;154(11):719-26.
2011: Paul M Ridker; Wolfgang Koenig; John J P Kastelein
C-reactive protein in the Heart Protection Study.
Lancet 2011;377(9781):1918; author reply 1918-9.
2011: Donald G Vidt; John T Monyak; Paul M Ridker; Martin J Schreiber; Michael D Cressman
Longitudinal assessment of estimated glomerular filtration rate in apparently healthy adults: a post hoc analysis from the JUPITER study (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin).
Clinical therapeutics 2011;33(6):717-25.
2011: Paul M Ridker; Robert J Glynn; Jean G MacFadyen; Daniel I Chasman
Kinesin-like protein 6 (KIF6) polymorphism and the efficacy of rosuvastatin in primary prevention.
Circulation. Cardiovascular genetics 2011;4(3):312-7.
2011: Peter Libby; Paul M Ridker; Göran K Hansson
Progress and challenges in translating the biology of atherosclerosis.
Nature 2011;473(7347):317-25.
2011: Vincent E Friedewald; Christie M Ballantyne; Michael H Davidson; Antonio M Gotto; Paul M Ridker; William C Roberts
The editor's roundtable: JUPITER follow-up.
The American journal of cardiology 2011;107(10):1549-57.
2011: Paul M Ridker
High-sensitivity C-reactive protein, vascular imaging, and vulnerable plaque: more evidence to support trials of antiinflammatory therapy for cardiovascular risk reduction.
Circulation. Cardiovascular imaging 2011;4(3):195-7.
2011: Andrew D Johnson; Toby Johnson; Martin G Larson; Lenore J Launer; Daniel Levy; Patricia B Munroe; Christopher Newton-Cheh; Bruce M Psaty; Kenneth Rice; Paul M Ridker; Lynda Rose; Cornelia M van Duijn; Germaine C Verwoert; Mark Caulfield; Aravinda Chakravarti; Daniel I Chasman; Georg Benedikt Ehret; Vilmundur Gudnason
Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals.
Hypertension 2011;57(5):903-10.
2011: Lu Wang; JoAnn E Manson; J Michael Gaziano; Simin Liu; Barbara Cochrane; Nancy R Cook; Paul M Ridker; Nader Rifai; Howard D Sesso
Circulating inflammatory and endothelial markers and risk of hypertension in white and black postmenopausal women.
Clinical chemistry 2011;57(5):729-36.
2011: Mary McGrae McDermott; Kiang Liu; Luigi Ferrucci; Lu Tian; Jack M Guralnik; Huimin Tao; Paul M Ridker; Michael H Criqui
Relation of interleukin-6 and vascular cellular adhesion molecule-1 levels to functional decline in patients with lower extremity peripheral arterial disease.
The American journal of cardiology 2011;107(9):1392-8.
2011: Judith Hsia; Jean G MacFadyen; John Monyak; Paul M Ridker
Cardiovascular event reduction and adverse events among subjects attaining low-density lipoprotein cholesterol <50 mg/dl with rosuvastatin. The JUPITER trial (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin).
Journal of the American College of Cardiology 2011;57(16):1666-75.
2011: Robert Y L Zee; Patricia Pulido-Perez; Ricardo Perez-Fuentes; Paul M Ridker; Daniel I Chasman; Jose R Romero
Islet amyloid polypeptide gene variation (IAPP) and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.
Clinica chimica acta; international journal of clinical chemistry 2011;412(9-10):785-7.
2011: Guillaume Paré; Paul M Ridker; Lynda Rose; Maja Barbalic; Josée Dupuis; Abbas Dehghan; Joshua C Bis; Emelia J Benjamin; Dov Shiffman; Alexander N Parker; Daniel I Chasman
Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.
PLoS genetics 2011;7(4):e1001374.
2011: Tariq Ahmad; I-Min Lee; Guillaume Paré; Daniel I Chasman; Lynda Rose; Paul M Ridker; Samia Mora
Lifestyle interaction with fat mass and obesity-associated (FTO) genotype and risk of obesity in apparently healthy U.S. women.
Diabetes care 2011;34(3):675-80.
2011: Kathryn A Britton; Aruna D Pradhan; J Michael Gaziano; JoAnn E Manson; Paul M Ridker; Julie E Buring; Howard D Sesso
Hemoglobin A1c, body mass index, and the risk of hypertension in women.
American journal of hypertension 2011;24(3):328-34.
2011: Tariq Ahmad; Daniel I Chasman; Julie E Buring; I-Min Lee; Paul M Ridker; Brendan M Everett
Physical activity modifies the effect of LPL, LIPC, and CETP polymorphisms on HDL-C levels and the risk of myocardial infarction in women of European ancestry.
Circulation. Cardiovascular genetics 2011;4(1):74-80.
2011: Robert Y L Zee; Paul M Ridker; Daniel I Chasman
Genetic variants in eleven telomere-associated genes and the risk of incident cardio/cerebrovascular disease: The Women's Genome Health Study.
Clinica chimica acta; international journal of clinical chemistry 2011;412(1-2):199-202.
2011: Paul M Ridker
Increased mortality rates in the JUPITER trial.
Cardiology 2011;120(4):235; reply pg 236.
2011: Cheryl R Clark; Brent Coull; Lisa F Berkman; Julie E Buring; Paul M Ridker
Geographic variation in cardiovascular inflammation among healthy women in the Women's Health Study.
PloS one 2011;6(11):e27468.
2011: Johannes A N Dorresteijn; Nina P Paynter; Paul M Ridker; Ewout W Steyerberg; Yolanda van der Graaf; Frank L J Visseren; Annemarie M J Wassink; Nancy R Cook
Estimating treatment effects for individual patients based on the results of randomised clinical trials.
BMJ (Clinical research ed.) 2011;343():d5888.
2011: Markus Schürks; Paul M Ridker; Julie E Buring; Daniel I Chasman; Tobias Kurth
Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study.
PloS one 2011;6(7):e22106.
2011: Robert Y L Zee; Paul M Ridker; Daniel I Chasman
Mitochondrial uncoupling protein gene cluster variation (UCP2-UCP3) and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.
Atherosclerosis 2011;214(1):107-9.
2011: Jennifer E Ho; Daniel Levy; Lynda Rose; Andrew D Johnson; Paul M Ridker; Daniel I Chasman
Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study.
Journal of hypertension 2011;29(1):62-9.
2011: Wolfgang Koenig; Paul M Ridker
Rosuvastatin for primary prevention in patients with European systematic coronary risk evaluation risk ≥ 5% or Framingham risk >20%: post hoc analyses of the JUPITER trial requested by European health authorities.
European heart journal 2011;32(1):75-83.
2011: Emily G Kurtz; Paul M Ridker; Lynda M Rose; Nancy R Cook; Brendan M Everett; Julie E Buring; Kathryn M Rexrode
Oral postmenopausal hormone therapy, C-reactive protein, and cardiovascular outcomes.
Menopause (New York, N.Y.) 2011;18(1):23-9.
2010: Tariq Ahmad; Daniel I Chasman; Samia Mora; Guillaume Paré; Nancy R Cook; Julie E Buring; Paul M Ridker; I-Min Lee
The fat-mass and obesity-associated (FTO) gene, physical activity, and risk of incident cardiovascular events in white women.
American heart journal 2010;160(6):1163-9.
2010: Paul M Ridker; Nina P Paynter; Jacqueline S Danik; Robert J Glynn
Interpretation of Mendelian randomization studies and the search for causal pathways in atherothrombosis: the need for caution.
Metabolic syndrome and related disorders 2010;8(6):465-9.
2010: Judith H Lichtman; Nancy P Lorenze; Gail D'Onofrio; John A Spertus; Stacy T Lindau; Thomas M Morgan; Jeph Herrin; Hector BUENO; Jennifer A Mattera; Paul M Ridker; Harlan M Krumholz
Variation in recovery: Role of gender on outcomes of young AMI patients (VIRGO) study design.
Circulation. Cardiovascular quality and outcomes 2010;3(6):684-93.
2010: Paul M Ridker; Robert J Glynn
The JUPITER Trial: responding to the critics.
The American journal of cardiology 2010;106(9):1351-6.
2010: Chunyan He; Peter Kraft; Daniel I Chasman; Julie E Buring; Constance Chen; Susan E Hankinson; Guillaume Paré; STEPHEN CHANOCK; Paul M Ridker; David J Hunter
A large-scale candidate gene association study of age at menarche and age at natural menopause.
Human genetics 2010;128(5):515-27.
2010: Cristi R King; Elena Deych; Paul E Milligan; Charles Eby; Petra Lenzini; Gloria Grice; Rhonda Porche-Sorbet; Paul M Ridker; Brian F Gage
Gamma-glutamyl carboxylase and its influence on warfarin dose.
Thrombosis and haemostasis 2010;104(4):750-4.
2010: Paul M Ridker; Jean G Macfadyen; Børge G Nordestgaard; Wolfgang Koenig; John J P Kastelein; Jacques Genest; Robert J Glynn
Rosuvastatin for primary prevention among individuals with elevated high-sensitivity c-reactive protein and 5% to 10% and 10% to 20% 10-year risk. Implications of the Justification for Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial for "intermediate risk".
Circulation. Cardiovascular quality and outcomes 2010;3(5):447-52.
2010: Paul M Ridker
Statin therapy for elevated hsCRP: what are the public health implications?
The American journal of managed care 2010;16(8):561-2.
2010: Vincent E Friedewald; Peter Ganz; Joel M Kremer; Philip J Mease; James R O'Dell; Thomas A Pearson; C Venkata S Ram; Paul M Ridker; Jane E Salmon; William C Roberts
AJC editor's consensus: rheumatoid arthritis and atherosclerotic cardiovascular disease.
The American journal of cardiology 2010;106(3):442-7.
2010: Samia Mora; Pia R Kamstrup; Nader Rifai; Børge G Nordestgaard; Julie E Buring; Paul M Ridker
Lipoprotein(a) and risk of type 2 diabetes.
Clinical chemistry 2010;56(8):1252-60.
2010: Robert Y L Zee; Amy J Castonguay; Nathaniel S Barton; Paul M Ridker
Relative leukocyte telomere length and risk of incident ischemic stroke in men: a prospective, nested case-control approach.
Rejuvenation research 2010;13(4):411-4.
2010: Paul M Ridker; Jacques Genest; S Matthijs Boekholdt; Peter Libby; Antonio M Gotto; Børge G Nordestgaard; Samia Mora; Jean G MacFadyen; Robert J Glynn; John J P Kastelein
HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial.
Lancet 2010;376(9738):333-9.
2010: Paul M Ridker; Jean MacFadyen; Peter Libby; Robert J Glynn
Relation of baseline high-sensitivity C-reactive protein level to cardiovascular outcomes with rosuvastatin in the Justification for Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER).
The American journal of cardiology 2010;106(2):204-9.
2010: David Conen; Paul M Ridker; Brendan M Everett; Usha B Tedrow; Lynda Rose; Nancy R Cook; Julie E Buring; Christine M Albert
A multimarker approach to assess the influence of inflammation on the incidence of atrial fibrillation in women.
European heart journal 2010;31(14):1730-6.
2010: Michael H Criqui; Lindsey A Ho; Julie O Denenberg; Paul M Ridker; Christina L Wassel; Mary McGrae McDermott
Biomarkers in peripheral arterial disease patients and near- and longer-term mortality.
Journal of vascular surgery 2010;52(1):85-90.
2010: Lu Qi; Marilyn C Cornelis; Peter Kraft; Kristopher J Stanya; W H Linda Kao; James S Pankow; Josée Dupuis; Jose C Florez; Caroline S Fox; Guillaume Paré; Qi Sun; Cynthia J Girman; Cathy C Laurie; Daniel B Mirel; Teri A Manolio; Daniel I Chasman; Eric Boerwinkle; Paul M Ridker; David J Hunter; James B Meigs; Chih-Hao Lee; Frank B Hu; Rob M van Dam
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.
Human molecular genetics 2010;19(13):2706-15.
2010: Paul M Ridker
Establishing a clinical basis for hsCRP in the prevention and treatment of cardiovascular disease.
Clinical chemistry 2010;56(7):1186-7.
2010: Paul M Ridker; Robert J Glynn
JUPITER, rosuvastatin, and the European Medicines Agency.
Lancet 2010;375(9731):2071.
2010: Guillaume Paré; Nancy R Cook; Paul M Ridker; Daniel I Chasman
On the use of variance per genotype as a tool to identify quantitative trait interaction effects: a report from the Women's Genome Health Study.
PLoS genetics 2010;6(6):e1000981.
2010: Usha B Tedrow; David Conen; Paul M Ridker; Nancy R Cook; Bruce A Koplan; JoAnn E Manson; Julie E Buring; Christine M Albert
The long- and short-term impact of elevated body mass index on the risk of new atrial fibrillation the WHS (women's health study).
Journal of the American College of Cardiology 2010;55(21):2319-27.
2010: Michelle A Albert; Yvette Cozier; Paul M Ridker; Julie R Palmer; Robert J Glynn; Lynda Rose; Nitsan Halevy; Lynn Rosenberg
Perceptions of race/ethnic discrimination in relation to mortality among Black women: results from the Black Women's Health Study.
Archives of internal medicine 2010;170(10):896-904.
2010: Samia Mora; James D Otvos; Robert S Rosenson; Aruna Pradhan; Julie E Buring; Paul M Ridker
Lipoprotein particle size and concentration by nuclear magnetic resonance and incident type 2 diabetes in women.
Diabetes 2010;59(5):1153-60.
2010: Robert J Glynn; Wolfgang Koenig; Børge G Nordestgaard; James Shepherd; Paul M Ridker
Rosuvastatin for primary prevention in older persons with elevated C-reactive protein and low to average low-density lipoprotein cholesterol levels: exploratory analysis of a randomized trial.
Annals of internal medicine 2010;152(8):488-96, W174.
2010: Paul M Ridker
Psoriasis, inflammation, and vascular risk: a problem more than skin deep?
European heart journal 2010;31(8):902-4.
2010: Paul M Ridker
Statin therapy for low-LDL, high-hsCRP patients: from JUPITER to CORONA.
Clinical chemistry 2010;56(4):505-7.
2010: Meian He; Marilyn C Cornelis; Peter Kraft; Rob M van Dam; Qi Sun; Cathy C Laurie; Daniel B Mirel; Daniel I Chasman; Paul M Ridker; David J Hunter; Frank B Hu; Lu Qi
Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(4):885-90.
2010: Paul M Ridker; Jean MacFadyen; Michael Cressman; Robert J Glynn
Efficacy of rosuvastatin among men and women with moderate chronic kidney disease and elevated high-sensitivity C-reactive protein: a secondary analysis from the JUPITER (Justification for the Use of Statins in Prevention-an Intervention Trial Evaluating Rosuvastatin) trial.
Journal of the American College of Cardiology 2010;55(12):1266-73.
2010: Samia Mora; Robert J Glynn; Judith Hsia; Jean G MacFadyen; Jacques Genest; Paul M Ridker
Statins for the primary prevention of cardiovascular events in women with elevated high-sensitivity C-reactive protein or dyslipidemia: results from the Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) and meta-analysis of women from primary prevention trials.
Circulation 2010;121(9):1069-77.
2010: Nina P Paynter; Daniel I Chasman; Guillaume Paré; Julie E Buring; Nancy R Cook; JP Miletich; Paul M Ridker
Association between a literature-based genetic risk score and cardiovascular events in women.
JAMA : the journal of the American Medical Association 2010;303(7):631-7.
2010: Brendan M Everett; Robert J Glynn; Jean G MacFadyen; Paul M Ridker
Rosuvastatin in the prevention of stroke among men and women with elevated levels of C-reactive protein: justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER).
Circulation 2010;121(1):143-50.
2010: Mathew J Barber; Lara M Mangravite; Craig L Hyde; Daniel I Chasman; Joshua D Smith; Catherine A McCarty; Xiaohui Li; Russell A Wilke; Mark J Rieder; Paul T Williams; Paul M Ridker; Aurobindo Chatterjee; Jerome I Rotter; Deborah A Nickerson; Matthew Stephens; Ronald M Krauss
Genome-wide association of lipid-lowering response to statins in combined study populations.
PloS one 2010;5(3):e9763.
2010: Paul M Ridker
Inflammation, high-sensitivity C-reactive protein, and vascular protection.
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 2010;37(1):40-1.
2010: Sarah M Camhi; Marcia L Stefanick; Paul M Ridker; Deborah Sue Rohm Young
Changes in C-reactive protein from low-fat diet and/or physical activity in men and women with and without metabolic syndrome.
Metabolism: clinical and experimental 2010;59(1):54-61.
2009: Peter Libby; Paul M Ridker; Göran K Hansson
Inflammation in atherosclerosis: from pathophysiology to practice.
Journal of the American College of Cardiology 2009;54(23):2129-38.
2009: Christopher Newton-Cheh; Nancy R Cook; Martin VanDenburgh; Eric B Rimm; Paul M Ridker; Christine M Albert
A common variant at 9p21 is associated with sudden and arrhythmic cardiac death.
Circulation 2009;120(21):2062-8.
2009: Paul M Ridker; Jean G MacFadyen; Francisco A H Fonseca; Jacques Genest; Antonio M Gotto; John J P Kastelein; Wolfgang Koenig; Peter Libby; Alberto J Lorenzatti; Børge G Nordestgaard; James Shepherd; James T Willerson; Robert J Glynn
Number needed to treat with rosuvastatin to prevent first cardiovascular events and death among men and women with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin (JUPITER).
Circulation. Cardiovascular quality and outcomes 2009;2(6):616-23.
2009: Daniel I Chasman; Guillaume Paré; Samia Mora; Jemma C Hopewell; Gina Peloso; Robert Clarke; L Adrienne Cupples; Anders Hamsten; Sekar Kathiresan; Anders Mälarstig; José M Ordovas; Samuli Ripatti; Alex N Parker; JP Miletich; Paul M Ridker
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
PLoS genetics 2009;5(11):e1000730.
2009: swapnil rajpathak; Dharam J Kumbhani; Jill Crandall; Nir Barzilai; Michael H Alderman; Paul M Ridker
Statin therapy and risk of developing type 2 diabetes: a meta-analysis.
Diabetes care 2009;32(10):1924-9.
2009: David Conen; Kathryn M Rexrode; Mark A Creager; Paul M Ridker; Aruna D Pradhan
Metabolic syndrome, inflammation, and risk of symptomatic peripheral artery disease in women: a prospective study.
Circulation 2009;120(12):1041-7.
2009: Aruna D Pradhan; Brendan M Everett; Nancy R Cook; Nader Rifai; Paul M Ridker
Effects of initiating insulin and metformin on glycemic control and inflammatory biomarkers among patients with type 2 diabetes: the LANCET randomized trial.
JAMA : the journal of the American Medical Association 2009;302(11):1186-94.
2009: Jose R Romero; Paul M Ridker; Robert Y L Zee
Gene variation of the transient receptor potential cation channel, subfamily M, member 7 (TRPM7), and risk of incident ischemic stroke: prospective, nested, case-control study.
Stroke; a journal of cerebral circulation 2009;40(9):2965-8.
2009: Alessandra C Goulart; Kathryn M Rexrode; Suzanne Cheng; Lynda Rose; Julie E Buring; Paul M Ridker; Robert Y L Zee
Association of genetic variants with the metabolic syndrome in 20,806 white women: The Women's Health Genome Study.
American heart journal 2009;158(2):257-262.e1.
2009: Robert Y L Zee; Sherri E Michaud; Paul M Ridker
Mean telomere length and risk of incident venous thromboembolism: a prospective, nested case-control approach.
Clinica chimica acta; international journal of clinical chemistry 2009;406(1-2):148-50.
2009: Paul M Ridker
Testing the inflammatory hypothesis of atherothrombosis: scientific rationale for the cardiovascular inflammation reduction trial (CIRT).
Journal of thrombosis and haemostasis : JTH 2009;7 Suppl 1():332-9.
2009: Vincent E Friedewald; Kenneth S Kornman; James Beck; Robert Genco; Allison Goldfine; Peter Libby; Steven Offenbacher; Paul M Ridker; Thomas E Van Dyke; William C Roberts
The American Journal of Cardiology and Journal of Periodontology Editors' Consensus: periodontitis and atherosclerotic cardiovascular disease.
The American journal of cardiology 2009;104(1):59-68.
2009: Vincent E Friedewald; Kenneth S Kornman; James Beck; Robert Genco; Allison Goldfine; Peter Libby; Steven Offenbacher; Paul M Ridker; Thomas E Van Dyke; William C Roberts
The American Journal of Cardiology and Journal of Periodontology editors' consensus: periodontitis and atherosclerotic cardiovascular disease.
Journal of periodontology 2009;80(7):1021-32.
2009: Paul M Ridker
Moving toward new statin guidelines in a post-JUPITER world: principles to consider.
Current atherosclerosis reports 2009;11(4):249-56.
2009: Nancy R Cook; Paul M Ridker
Advances in measuring the effect of individual predictors of cardiovascular risk: the role of reclassification measures.
Annals of internal medicine 2009;150(11):795-802.
2009: Chunyan He; Peter Kraft; Constance Chen; Julie E Buring; Guillaume Paré; Susan E Hankinson; STEPHEN CHANOCK; Paul M Ridker; David J Hunter; Daniel I Chasman
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.
Nature genetics 2009;41(6):724-8.
2009: David Conen; Robert J Glynn; Paul M Ridker; Julie E Buring; Michelle A Albert
Socioeconomic status, blood pressure progression, and incident hypertension in a prospective cohort of female health professionals.
European heart journal 2009;30(11):1378-84.
2009: Paul M Ridker; Vincent E Friedewald; Michael H Davidson; James T Willerson; William C Roberts
The editor's roundtable: the JUPITER trial--initial results and clinical implications.
The American journal of cardiology 2009;103(10):1417-25.
2009: Paul M Ridker
The JUPITER trial: results, controversies, and implications for prevention.
Circulation. Cardiovascular quality and outcomes 2009;2(3):279-85.
2009: Christopher B Arant; Timothy R Wessel; Paul M Ridker; Marian B Olson; Steven E Reis; B Delia Johnson; Barry L Sharaf; Daniel F Pauly; Eileen Handberg; Issam Zineh; George Sopko; Sheryl F Kelsey; C Noel Bairey Merz; Carl J Pepine
Multimarker approach predicts adverse cardiovascular events in women evaluated for suspected ischemia: results from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation.
Clinical cardiology 2009;32(5):244-50.
2009: Paul M Ridker; Daniel H Solomon
Should patients with rheumatoid arthritis receive statin therapy?
Arthritis and rheumatism 2009;60(5):1205-9.
2009: Samia Mora; Nader Rifai; Julie E Buring; Paul M Ridker
Comparison of LDL cholesterol concentrations by Friedewald calculation and direct measurement in relation to cardiovascular events in 27,331 women.
Clinical chemistry 2009;55(5):888-94.
2009: Nina P Paynter; Nancy R Cook; Brendan M Everett; Howard D Sesso; Julie E Buring; Paul M Ridker
Prediction of incident hypertension risk in women with currently normal blood pressure.
The American journal of medicine 2009;122(5):464-71.
2009: Robert Y L Zee; Sherri E Michaud; Soren Germer; Paul M Ridker
Association of shorter mean telomere length with risk of incident myocardial infarction: a prospective, nested case-control approach.
Clinica chimica acta; international journal of clinical chemistry 2009;403(1-2):139-41.
2009: Robert J Glynn; Eleanor Danielson; Francisco A H Fonseca; Jacques Genest; Antonio M Gotto; John J P Kastelein; Wolfgang Koenig; Peter Libby; Alberto J Lorenzatti; Jean G MacFadyen; Børge G Nordestgaard; James Shepherd; James T Willerson; Paul M Ridker
A randomized trial of rosuvastatin in the prevention of venous thromboembolism.
The New England journal of medicine 2009;360(18):1851-61.
2009: Paul M Ridker; Eleanor Danielson; Francisco Ah Fonseca; Jacques Genest; Antonio M Gotto; John Jp Kastelein; Wolfgang Koenig; Peter Libby; Alberto J Lorenzatti; Jean G Macfadyen; Børge G Nordestgaard; James Shepherd; James T Willerson; Robert J Glynn
Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial.
Lancet 2009;373(9670):1175-82.
2009: Guillaume Paré; Daniel I Chasman; Alexander N Parker; Robert R Y Zee; Anders Mälarstig; Udo Seedorf; Rory Collins; Hugh Watkins; Anders Hamsten; Joseph P Miletich; Paul M Ridker
Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.
Circulation. Cardiovascular genetics 2009;2(2):142-50.
2009: Jacqueline S Danik; Guillaume Paré; Daniel I Chasman; Robert Y L Zee; David J Kwiatkowski; Alex Parker; JP Miletich; Paul M Ridker
Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
Circulation. Cardiovascular genetics 2009;2(2):134-41.
2009: Michelle A Albert; Guillaume Pare; Alanna Morris; Lynda Rose; Julie Buring; Paul M Ridker; Robert Y L Zee
Candidate genetic variants in the fibrinogen, methylenetetrahydrofolate reductase, and intercellular adhesion molecule-1 genes and plasma levels of fibrinogen, homocysteine, and intercellular adhesion molecule-1 among various race/ethnic groups: data from the Women's Genome Health Study.
American heart journal 2009;157(4):777-83.e1.
2009: Robert Y L Zee; Vadim Bubes; Sanjay Shrivastava; Paul M Ridker; Robert J Glynn
Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.
Clinica chimica acta; international journal of clinical chemistry 2009;402(1-2):189-92.
2009: B M Everett; R J Glynn; J E Buring; Paul M Ridker
Lipid biomarkers, hormone therapy and the risk of venous thromboembolism in women.
Journal of thrombosis and haemostasis : JTH 2009;7(4):588-96.
2009: Daniel I Chasman; Dov Shiffman; Robert Y L Zee; Judy Z Louie; May M Luke; Charles M Rowland; Joseph J Catanese; Julie E Buring; James J Devlin; Paul M Ridker
Polymorphism in the apolipoprotein(a) gene, plasma lipoprotein(a), cardiovascular disease, and low-dose aspirin therapy.
Atherosclerosis 2009;203(2):371-6.
2009: David Conen; Suzanne Cheng; Lori L Steiner; Julie E Buring; Paul M Ridker; Robert Y L Zee
Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.
Journal of hypertension 2009;27(3):476-83.
2009: Xingyu Wang; Suzanne Cheng; Victoria H Brophy; Henry A Erlich; Christine Mannhalter; Klaus Berger; Wolfgang Lalouschek; Warren S Browner; Yu Shi; E Bernd Ringelstein; Christof Kessler; Jan Luedemann; Klaus Lindpaintner; Lisheng Liu; Paul M Ridker; Robert Y L Zee; Nancy R Cook
A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
Stroke; a journal of cerebral circulation 2009;40(3):683-95.
2009: Kausik K Ray; Christopher P Cannon; Richard Cairns; David A Morrow; Paul M Ridker; Eugene Braunwald
Prognostic utility of apoB/AI, total cholesterol/HDL, non-HDL cholesterol, or hs-CRP as predictors of clinical risk in patients receiving statin therapy after acute coronary syndromes: results from PROVE IT-TIMI 22.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(3):424-30.
2009: Samia Mora; James D Otvos; Nader Rifai; Robert S Rosenson; Julie E Buring; Paul M Ridker
Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women.
Circulation 2009;119(7):931-9.
2009: Robert Y L Zee; Robert J Glynn; Suzanne Cheng; Lori Steiner; Lynda Rose; Paul M Ridker
An evaluation of candidate genes of inflammation and thrombosis in relation to the risk of venous thromboembolism: The Women's Genome Health Study.
Circulation. Cardiovascular genetics 2009;2(1):57-62.
2009: Paul M Ridker; Guillaume Paré; Alex N Parker; Robert Y L Zee; JP Miletich; Daniel I Chasman
Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.
Circulation. Cardiovascular genetics 2009;2(1):26-33.
2009: Markus Schürks; Tobias Kurth; Paul M Ridker; Julie E Buring; Robert Y L Zee
Association between polymorphisms in the beta2-adrenergic receptor gene with myocardial infarction and ischaemic stroke in women.
Thrombosis and haemostasis 2009;101(2):351-8.
2009: Paul M Ridker
Myocardial infarction in a 72-year-old woman with low LDL-C and increased hsCRP: implications for statin therapy.
Clinical chemistry 2009;55(2):369-74; discussion 374-5.
2009: Andy Itsara; Gregory Cooper; Carl Baker; Santhosh Girirajan; Jun Li; Devin Absher; Ronald M Krauss; Richard Myers; Paul M Ridker; Daniel I Chasman; Heather C Mefford; Phyllis Ying; Deborah A Nickerson; Evan E Eichler
Population analysis of large copy number variants and hotspots of human genetic disease.
American journal of human genetics 2009;84(2):148-61.
2009: Robert J Glynn; Jean G MacFadyen; Paul M Ridker
Tracking of high-sensitivity C-reactive protein after an initially elevated concentration: the JUPITER Study.
Clinical chemistry 2009;55(2):305-12.
2009: Paul M Ridker
C-reactive protein: eighty years from discovery to emergence as a major risk marker for cardiovascular disease.
Clinical chemistry 2009;55(2):209-15.
2009: Tamra E Meyer; Dov Shiffman; Alanna C Morrison; Charles M Rowland; Judy Z Louie; Lance A Bare; David A Ross; Andre R Arellano; Daniel I Chasman; Paul M Ridker; James S Pankow; Josef Coresh; Mary J Malloy; John P Kane; Stephen G Ellis; James J Devlin; Eric Boerwinkle
GOSR2 Lys67Arg is associated with hypertension in whites.
American journal of hypertension 2009;22(2):163-8.
2009: Markus Schürks; Tobias Kurth; Paul M Ridker; Julie E Buring; Robert Y L Zee
Association between polymorphisms in the beta2-adrenoceptor gene and migraine in women.
Headache 2009;49(2):235-44.
2009: Nina P Paynter; Daniel I Chasman; Julie E Buring; Dov Shiffman; Nancy R Cook; Paul M Ridker
Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3.
Annals of internal medicine 2009;150(2):65-72.
2009: Tobias Kurth; Paul E de Jong; Nancy R Cook; Julie E Buring; Paul M Ridker
Kidney function and risk of cardiovascular disease and mortality in women: a prospective cohort study.
BMJ (Clinical research ed.) 2009;338():b2392.
2009: Aruna D Pradhan; Nancy R Cook; JoAnn E Manson; Paul M Ridker; Julie E Buring
A randomized trial of low-dose aspirin in the prevention of clinical type 2 diabetes in women.
Diabetes care 2009;32(1):3-8.
2009: Brendan M Everett; Sandeep Bansal; Nader Rifai; Julie E Buring; Paul M Ridker
Interleukin-18 and the risk of future cardiovascular disease among initially healthy women.
Atherosclerosis 2009;202(1):282-8.
2008: Vincent E Friedewald; Jennifer C Cather; Joel M Gelfand; Kenneth B Gordon; Gary H Gibbons; Scott M Grundy; Michael T Jarratt; James G Krueger; Paul M Ridker; Neil Stone; William C Roberts
AJC editor's consensus: psoriasis and coronary artery disease.
The American journal of cardiology 2008;102(12):1631-43.
2008: Julie Lin; Robert J Glynn; Nader Rifai; JoAnn E Manson; Paul M Ridker; David M Nathan; Debra A Schaumberg
Inflammation and progressive nephropathy in type 1 diabetes in the diabetes control and complications trial.
Diabetes care 2008;31(12):2338-43.
2008: Paul M Ridker; Nina P Paynter; Nader Rifai; J Michael Gaziano; Nancy R Cook
C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men.
Circulation 2008;118(22):2243-51, 4p following 2251.
2008: Paul M Ridker; Eleanor Danielson; Francisco A H Fonseca; Jacques Genest; Antonio M Gotto; John J P Kastelein; Wolfgang Koenig; Peter Libby; Alberto J Lorenzatti; Jean G MacFadyen; Børge G Nordestgaard; James Shepherd; James T Willerson; Robert J Glynn
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
The New England journal of medicine 2008;359(21):2195-207.
2008: Robert Y L Zee; Hooman Hennessey; Sherri E Michaud; Paul M Ridker
Genetic variants within the interleukin-1 gene cluster, and risk of incident myocardial infarction, and ischemic stroke: a nested case-control approach.
Atherosclerosis 2008;201(1):124-9.
2008: Daniel I Chasman; Guillaume Paré; Robert Y L Zee; Alex N Parker; Nancy R Cook; Julie E Buring; David J Kwiatkowski; Lynda M Rose; Joshua D Smith; Paul T Williams; Mark J Rieder; Jerome I Rotter; Deborah A Nickerson; Ronald M Krauss; JP Miletich; Paul M Ridker
Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.
Circulation. Cardiovascular genetics 2008;1(1):21-30.
2008: David Conen; Jose Torres; Paul M Ridker
Differential citation rates of major cardiovascular clinical trials according to source of funding: a survey from 2000 to 2005.
Circulation 2008;118(13):1321-7.
2008: Samia Mora; Nader Rifai; Julie E Buring; Paul M Ridker
Fasting compared with nonfasting lipids and apolipoproteins for predicting incident cardiovascular events.
Circulation 2008;118(10):993-1001.
2008: David Conen; Robert J Glynn; Julie E Buring; Paul M Ridker; Robert Y L Zee
Association of renin-angiotensin and endothelial nitric oxide synthase gene polymorphisms with blood pressure progression and incident hypertension: prospective cohort study.
Journal of hypertension 2008;26(9):1780-6.
2008: B F Gage; C Eby; J A Johnson; E Deych; M J Rieder; Paul M Ridker; Paul E Milligan; G Grice; P Lenzini; A E Rettie; C L Aquilante; L Grosso; Sharon Marsh; T Langaee; L E Farnett; D Voora; D L Veenstra; R J Glynn; A Barrett; howard mcleod
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin.
Clinical pharmacology and therapeutics 2008;84(3):326-31.
2008: Charles B Eaton; Robert Gramling; Donna R Parker; Mary B Roberts; Bing Lu; Paul M Ridker
Prospective association of vascular endothelial growth factor-A (VEGF-A) with coronary heart disease mortality in southeastern New England.
Atherosclerosis 2008;200(1):221-7.
2008: Paul M Ridker; Josh D Silvertown
Inflammation, C-reactive protein, and atherothrombosis.
Journal of periodontology 2008;79(8 Suppl):1544-51.
2008: Jacqueline Suk Danik; Nader Rifai; Julie E Buring; Paul M Ridker
Lipoprotein(a), hormone replacement therapy, and risk of future cardiovascular events.
Journal of the American College of Cardiology 2008;52(2):124-31.
2008: Peristera Paschou; Petros Drineas; Jamey Lewis; Caroline M Nievergelt; Deborah A Nickerson; Joshua D Smith; Paul M Ridker; Daniel I Chasman; Ronald M Krauss; Elad Ziv
Tracing sub-structure in the European American population with PCA-informative markers.
PLoS genetics 2008;4(7):e1000114.
2008: Guillaume Paré; Daniel I Chasman; Mark Kellogg; Robert Y L Zee; Nader Rifai; Sunita Badola; Joseph P Miletich; Paul M Ridker
Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.
PLoS genetics 2008;4(7):e1000118.
2008: Paul M Ridker
The time for cardiovascular inflammation reduction trials has arrived: how low to go for hsCRP?
Arteriosclerosis, thrombosis, and vascular biology 2008;28(7):1222-4.
2008: Cristi R King; Rhonda M Porche-Sorbet; Brian F Gage; Paul M Ridker; Yannick Renaud; Michael S Phillips; Charles Eby
Performance of commercial platforms for rapid genotyping of polymorphisms affecting warfarin dose.
American journal of clinical pathology 2008;129(6):876-83.
2008: Alexander P Reiner; Mathew Barber; Yongtao Guan; Paul M Ridker; Leslie A Lange; Daniel I Chasman; Jeremy Walston; Gregory Cooper; Nancy S Jenny; Mark J Rieder; J Peter Durda; joshua smith; John Novembre; Russell P Tracy; Jerome I Rotter; Matthew Stephens; Deborah A Nickerson; Ronald M Krauss
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
American journal of human genetics 2008;82(5):1193-201.
2008: Paul M Ridker; Guillaume Pare; Alex Parker; Robert Y L Zee; Jacqueline S Danik; Julie E Buring; David Kwiatkowski; Nancy R Cook; Joseph P Miletich; Daniel I Chasman
Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.
American journal of human genetics 2008;82(5):1185-92.
2008: Anders Mälarstig; Per Eriksson; Lynda Rose; Kirsti Diehl; Anders Hamsten; Paul M Ridker; Robert Y L Zee
Genetic variants of tumor necrosis factor superfamily, member 4 (TNFSF4), and risk of incident atherothrombosis and venous thromboembolism.
Clinical chemistry 2008;54(5):833-40.
2008: Kathryn M Rexrode; Paul M Ridker; Hillary H Hegener; Julie E Buring; JoAnn E Manson; Robert Y L Zee
Genetic variation of the androgen receptor and risk of myocardial infarction and ischemic stroke in women.
Stroke; a journal of cerebral circulation 2008;39(5):1590-2.
2008: Vincent E Friedewald; Jennifer C Cather; Kenneth B Gordon; Arthur Kavanaugh; Paul M Ridker; William C Roberts
The editor's roundtable: psoriasis, inflammation, and coronary artery disease.
The American journal of cardiology 2008;101(8):1119-26.
2008: Brendan M Everett; Robert J Glynn; Eleanor Danielson; Paul M Ridker
Combination therapy versus monotherapy as initial treatment for stage 2 hypertension: a prespecified subgroup analysis of a community-based, randomized, open-label trial.
Clinical therapeutics 2008;30(4):661-72.
2008: Robert Y L Zee; Soren Germer; Abraham Thomas; Annaswammy Raji; Brian Rhees; Paul M Ridker; Klaus Lindpaintner; Gordon H Williams; David M Nathan; Mitchell Martin
C-reactive protein gene variation and type 2 diabetes mellitus: a case-control study.
Atherosclerosis 2008;197(2):931-6.
2008: Robert Y L Zee; Sherri E Michaud; Kirsti Diehl; Daniel I Chasman; Joseph Emmerich; Pascale Gaussem; Martine Aiach; Paul M Ridker
Purinergic receptor P2Y, G-protein coupled, 12 gene variants and risk of incident ischemic stroke, myocardial infarction, and venous thromboembolism.
Atherosclerosis 2008;197(2):694-9.
2008: Joseph Emmerich; Paul M Ridker
Can fishing for new genes catch patients at risk of coronary artery disease?
Clinical chemistry 2008;54(3):453-5.
2008: Emily B Levitan; Nancy R Cook; Meir J Stampfer; Paul M Ridker; Kathryn M Rexrode; Julie E Buring; JoAnn E Manson; Simin Liu
Dietary glycemic index, dietary glycemic load, blood lipids, and C-reactive protein.
Metabolism: clinical and experimental 2008;57(3):437-43.
2008: Michelle A Albert; Robert J Glynn; Julie E Buring; Paul M Ridker
Differential effect of soluble intercellular adhesion molecule-1 on the progression of atherosclerosis as compared to arterial thrombosis: a prospective analysis of the Women's Health Study.
Atherosclerosis 2008;197(1):297-302.
2008: Aruna D Pradhan; Sanjay Shrivastava; Nancy R Cook; Nader Rifai; Mark A Creager; Paul M Ridker
Symptomatic peripheral arterial disease in women: nontraditional biomarkers of elevated risk.
Circulation 2008;117(6):823-31.
2008: Paul M Ridker
High-sensitivity C-reactive protein as a predictor of all-cause mortality: implications for research and patient care.
Clinical chemistry 2008;54(2):234-7.
2008: Paul M Ridker; Daniel I Chasman; Robert Y L Zee; Alex Parker; Lynda Rose; Nancy R Cook; Julie E Buring
Rationale, design, and methodology of the Women's Genome Health Study: a genome-wide association study of more than 25,000 initially healthy american women.
Clinical chemistry 2008;54(2):249-55.
2008: Dov Shiffman; Daniel I Chasman; Robert Y L Zee; Olga A Iakoubova; Judy Z Louie; James J Devlin; Paul M Ridker
A kinesin family member 6 variant is associated with coronary heart disease in the Women's Health Study.
Journal of the American College of Cardiology 2008;51(4):444-8.
2008: Himabindu Vidula; Lu Tian; Kiang Liu; Michael H Criqui; Luigi Ferrucci; William H Pearce; Philip Greenland; David Green; Jin Tan; Daniel B Garside; Jack Guralnik; Paul M Ridker; Nader Rifai; Mary McGrae McDermott
Biomarkers of inflammation and thrombosis as predictors of near-term mortality in patients with peripheral arterial disease: a cohort study.
Annals of internal medicine 2008;148(2):85-93.
2008: Isabella Kardys; Nader Rifai; Olivier Meilhac; Jean-Baptiste Michel; Jose Luis Martin-Ventura; Julie E Buring; Peter Libby; Paul M Ridker
Plasma concentration of heat shock protein 27 and risk of cardiovascular disease: a prospective, nested case-control study.
Clinical chemistry 2008;54(1):139-46.
2008: Paul M Ridker
Fasting versus nonfasting triglycerides and the prediction of cardiovascular risk: do we need to revisit the oral triglyceride tolerance test?
Clinical chemistry 2008;54(1):11-3.
2007: Paul M Ridker
Inflammatory biomarkers and risks of myocardial infarction, stroke, diabetes, and total mortality: implications for longevity.
Nutrition reviews 2007;65(12 Pt 2):S253-9.
2007: Paul M Ridker; Francisco A H Fonseca; Jacques Genest; Antonio M Gotto; John J P Kastelein; Nardev S Khurmi; Wolfgang Koenig; Peter Libby; Alberto J Lorenzatti; Borge G Nordestgaard; James Shepherd; James T Willerson; Robert J Glynn
Baseline characteristics of participants in the JUPITER trial, a randomized placebo-controlled primary prevention trial of statin therapy among individuals with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein.
The American journal of cardiology 2007;100(11):1659-64.
2007: Yiqing Song; JoAnn E Manson; James B Meigs; Paul M Ridker; Julie E Buring; Simin Liu
Comparison of usefulness of body mass index versus metabolic risk factors in predicting 10-year risk of cardiovascular events in women.
The American journal of cardiology 2007;100(11):1654-8.
2007: David Conen; Robert J Glynn; Julie E Buring; Paul M Ridker; Robert Y L Zee
Natriuretic peptide precursor a gene polymorphisms and risk of blood pressure progression and incident hypertension.
Hypertension 2007;50(6):1114-9.
2007: Robert Y L Zee; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Nader Rifai; Julie E Buring; Paul M Ridker
Intercellular adhesion molecule 1 (ICAM1) Lys56Met and Gly241Arg gene variants, plasma-soluble ICAM1 concentrations, and risk of incident cardiovascular events in 23,014 initially healthy white women.
Stroke; a journal of cerebral circulation 2007;38(12):3152-7.
2007: David Conen; Paul M Ridker; Samia Mora; Julie E Buring; Robert J Glynn
Blood pressure and risk of developing type 2 diabetes mellitus: the Women's Health Study.
European heart journal 2007;28(23):2937-43.
2007: Samia Mora; Nancy Cook; Julie E Buring; Paul M Ridker; I-Min Lee
Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms.
Circulation 2007;116(19):2110-8.
2007: Robert J Glynn; Paul M Ridker; Samuel Z Goldhaber; Julie E Buring
Effect of low-dose aspirin on the occurrence of venous thromboembolism: a randomized trial.
Annals of internal medicine 2007;147(8):525-33.
2007: Robert Y L Zee; Paul M Ridker
Two common gene variants on chromosome 9 and risk of atherothrombosis.
Stroke; a journal of cerebral circulation 2007;38(10):e111.
2007: Kathryn M Rexrode; Paul M Ridker; Hillary H Hegener; Julie E Buring; JoAnn E Manson; Robert Y L Zee
Polymorphisms and haplotypes of the estrogen receptor-beta gene (ESR2) and cardiovascular disease in men and women.
Clinical chemistry 2007;53(10):1749-56.
2007: Robert J Glynn; Paul M Ridker; Samuel Z Goldhaber; Robert Y L Zee; Julie E Buring
Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study.
Circulation 2007;116(13):1497-503.
2007: Jacqueline Suk Danik; Paul M Ridker
Genetic determinants of C-reactive protein.
Current atherosclerosis reports 2007;9(3):195-203.
2007: David Conen; Paul M Ridker; Julie E Buring; Robert J Glynn
Risk of cardiovascular events among women with high normal blood pressure or blood pressure progression: prospective cohort study.
BMJ (Clinical research ed.) 2007;335(7617):432.
2007: David Conen; Paul M Ridker
Clinical significance of high-sensitivity C-reactive protein in cardiovascular disease.
Biomarkers in medicine 2007;1(2):229-41.
2007: Aruna D Pradhan; Nader Rifai; Julie E Buring; Paul M Ridker
Hemoglobin A1c predicts diabetes but not cardiovascular disease in nondiabetic women.
The American journal of medicine 2007;120(8):720-7.
2007: Sandeep Bansal; Julie E Buring; Nader Rifai; Samia Mora; Frank M Sacks; Paul M Ridker
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women.
JAMA : the journal of the American Medical Association 2007;298(3):309-16.
2007: Yiqing Song; JoAnn E Manson; Lesley Tinker; Nader Rifai; Nancy R Cook; Frank B Hu; Gökhan S Hotamisligil; Paul M Ridker; Beatriz L Rodriguez; Karen L Margolis; Albert Oberman; Simin Liu
Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of women.
Diabetes 2007;56(7):1898-904.
2007: Shumin M Zhang; Jennifer Lin; Nancy R Cook; I-Min Lee; JoAnn E Manson; Julie E Buring; Paul M Ridker
C-reactive protein and risk of breast cancer.
Journal of the National Cancer Institute 2007;99(11):890-4.
2007: Sandeep Bansal; Paul M Ridker
Comparison of characteristics of future myocardial infarctions in women with baseline high versus baseline low levels of high-sensitivity C-reactive protein.
The American journal of cardiology 2007;99(11):1500-3.
2007: Paul M Ridker
C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus.
Journal of the American College of Cardiology 2007;49(21):2129-38.
2007: Paul M Ridker; Brendan M Everett
Letter by Ridker and Everett regarding article, "The inflammatory hypothesis: any progress in risk stratification and therapeutic targets?".
Circulation 2007;115(20):e475; author reply e476.
2007: Michelle A Albert; Robert J Glynn; Julie E Buring; Paul M Ridker
Relation between soluble intercellular adhesion molecule-1, homocysteine, and fibrinogen levels and race/ethnicity in women without cardiovascular disease.
The American journal of cardiology 2007;99(9):1246-51.
2007: Peng-yun A Huang; Julie E Buring; Paul M Ridker; Robert J Glynn
Awareness, accuracy, and predictive validity of self-reported cholesterol in women.
Journal of general internal medicine 2007;22(5):606-13.
2007: Robert Y L Zee; Samia Mora; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Nader Rifai; Julie E Buring; Paul M Ridker
Homocysteine, 5,10-methylenetetrahydrofolate reductase 677C>T polymorphism, nutrient intake, and incident cardiovascular disease in 24,968 initially healthy women.
Clinical chemistry 2007;53(5):845-51.
2007: David T Miller; Paul M Ridker; Peter Libby; David J Kwiatkowski
Atherosclerosis: the path from genomics to therapeutics.
Journal of the American College of Cardiology 2007;49(15):1589-99.
2007: Paul M Ridker; Nancy R Cook
Biomarkers for prediction of cardiovascular events.
The New England journal of medicine 2007;356(14):1472-3; author reply 1474-5.
2007: Marc S Sabatine; David A Morrow; Kathleen Jablonski; Madeline Murguia Rice; J Wayne Warnica; Michael J Domanski; Judith Hsia; Bernard J Gersh; Nader Rifai; Paul M Ridker; Marc A Pfeffer; Eugene Braunwald
Prognostic significance of the Centers for Disease Control/American Heart Association high-sensitivity C-reactive protein cut points for cardiovascular and other outcomes in patients with stable coronary artery disease.
Circulation 2007;115(12):1528-36.
2007: Debra A Schaumberg; William Christen; Julie E Buring; Robert J Glynn; Nader Rifai; Paul M Ridker
High-sensitivity C-reactive protein, other markers of inflammation, and the incidence of macular degeneration in women.
Archives of ophthalmology 2007;125(3):300-5.
2007: Paul M Ridker; Julie E Buring; Nader Rifai; Nancy R Cook
Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score.
JAMA : the journal of the American Medical Association 2007;297(6):611-9.
2007: Howard D Sesso; Lu Wang; Julie E Buring; Paul M Ridker; J Michael Gaziano
Comparison of interleukin-6 and C-reactive protein for the risk of developing hypertension in women.
Hypertension 2007;49(2):304-10.
2007: Robert J Glynn; Samuel Z Goldhaber; Paul M Ridker
D-dimer and duration of anticoagulation.
The New England journal of medicine 2007;356(4):422-3; author reply 423.
2007: Christopher D Owens; Paul M Ridker; Michael Belkin; Allen D Hamdan; Frank B Pomposelli; Frank Logerfo; Mark A Creager; Michael S Conte
Elevated C-reactive protein levels are associated with postoperative events in patients undergoing lower extremity vein bypass surgery.
Journal of vascular surgery 2007;45(1):2-9; discussion 9.
2006: Michelle A Albert; Robert J Glynn; Julie E Buring; Paul M Ridker
Impact of traditional and novel risk factors on the relationship between socioeconomic status and incident cardiovascular events.
Circulation 2006;114(24):2619-26.
2006: Nancy A Shadick; Nancy R Cook; Elizabeth W Karlson; Paul M Ridker; Nancy E Maher; JoAnn E Manson; Julie E Buring; I-Min Lee
C-reactive protein in the prediction of rheumatoid arthritis in women.
Archives of internal medicine 2006;166(22):2490-4.
2006: Brendan M Everett; Tobias Kurth; Julie E Buring; Paul M Ridker
The relative strength of C-reactive protein and lipid levels as determinants of ischemic stroke compared with coronary heart disease in women.
Journal of the American College of Cardiology 2006;48(11):2235-42.
2006: Melissa E Weinberg; JoAnn E Manson; Julie E Buring; Nancy R Cook; Ellen W Seely; Paul M Ridker; Kathryn M Rexrode
Low sex hormone-binding globulin is associated with the metabolic syndrome in postmenopausal women.
Metabolism: clinical and experimental 2006;55(11):1473-80.
2006: J Suk Danik; Daniel I Chasman; C P Cannon; David T Miller; Robert Y L Zee; Piotr Kozlowski; David J Kwiatkowski; Paul M Ridker
Influence of genetic variation in the C-reactive protein gene on the inflammatory response during and after acute coronary ischemia.
Annals of human genetics 2006;70(Pt 6):705-16.
2006: Hillary H Hegener; I-Min Lee; Nancy R Cook; Paul M Ridker; Robert Y L Zee
Association of adiponectin gene variations with risk of incident myocardial infarction and ischemic stroke: a nested case-control study.
Clinical chemistry 2006;52(11):2021-7.
2006: Jacqueline Suk Danik; Nader Rifai; Julie E Buring; Paul M Ridker
Lipoprotein(a), measured with an assay independent of apolipoprotein(a) isoform size, and risk of future cardiovascular events among initially healthy women.
JAMA : the journal of the American Medical Association 2006;296(11):1363-70.
2006: Robert Y L Zee; S E Michaud; Hillary H Hegener; Kirsti Diehl; Paul M Ridker
A prospective replication study of five gene variants previously associated with risk of myocardial infarction.
Journal of thrombosis and haemostasis : JTH 2006;4(9):2093-5.
2006: Piotr Kozlowski; David T Miller; Robert Y L Zee; Jacqueline Suk Danik; Daniel I Chasman; Ross Lazarus; Nancy R Cook; Paul M Ridker; David J Kwiatkowski
Lack of association between genetic variation in 9 innate immunity genes and baseline CRP levels.
Annals of human genetics 2006;70(Pt 5):574-86.
2006: Michelle A Albert; Paul M Ridker
C-reactive protein as a risk predictor: do race/ethnicity and gender make a difference?
Circulation 2006;114(5):e67-74.
2006: Hillary H Hegener; Kirsti Diehl; T Kurth; J M Gaziano; Paul M Ridker; Robert Y L Zee
Polymorphisms of prostaglandin-endoperoxide synthase 2 gene, and prostaglandin-E receptor 2 gene, C-reactive protein concentrations and risk of atherothrombosis: a nested case-control approach.
Journal of thrombosis and haemostasis : JTH 2006;4(8):1718-22.
2006: Samia Mora; Nader Rifai; Julie E Buring; Paul M Ridker
Additive value of immunoassay-measured fibrinogen and high-sensitivity C-reactive protein levels for predicting incident cardiovascular events.
Circulation 2006;114(5):381-7.
2006: Robert Y L Zee; Victoria H Brophy; Suzanne Cheng; Hillary H Hegener; Henry A Erlich; Paul M Ridker
Polymorphisms of the phosphodiesterase 4D, cAMP-specific (PDE4D) gene and risk of ischemic stroke: a prospective, nested case-control evaluation.
Stroke; a journal of cerebral circulation 2006;37(8):2012-7.
2006: Jessica L Mega; David A Morrow; Christopher P Cannon; Sabina Murphy; Richard Cairns; Paul M Ridker; Eugene Braunwald
Cholesterol, C-reactive protein, and cerebrovascular events following intensive and moderate statin therapy.
Journal of thrombosis and thrombolysis 2006;22(1):71-6.
2006: Robert Y L Zee; Suzanne Cheng; Hillary H Hegener; Henry A Erlich; Paul M Ridker
Genetic variants of arachidonate 5-lipoxygenase-activating protein, and risk of incident myocardial infarction and ischemic stroke: a nested case-control approach.
Stroke; a journal of cerebral circulation 2006;37(8):2007-11.
2006: Robert Y L Zee; Kirsti Diehl; Paul M Ridker
Complement factor H Y402H gene polymorphism, C-reactive protein, and risk of incident myocardial infarction, ischaemic stroke, and venous thromboembolism: a nested case-control study.
Atherosclerosis 2006;187(2):332-5.
2006: Paul M Ridker; Nancy R Cook; Julie E Buring
Use of aspirin as primary prevention of cardiovascular events.
JAMA : the journal of the American Medical Association 2006;296(4):391; author reply 391-2.
2006: Nancy R Cook; Julie E Buring; Paul M Ridker
The effect of including C-reactive protein in cardiovascular risk prediction models for women.
Annals of internal medicine 2006;145(1):21-9.
2006: Robert Y L Zee; Jose R Romero; Jessica L Gould; Dennis A Ricupero; Paul M Ridker
Polymorphisms in the advanced glycosylation end product-specific receptor gene and risk of incident myocardial infarction or ischemic stroke.
Stroke; a journal of cerebral circulation 2006;37(7):1686-90.
2006: Paul M Ridker; Eleanor Danielson; Nader Rifai; Robert J Glynn
Valsartan, blood pressure reduction, and C-reactive protein: primary report of the Val-MARC trial.
Hypertension 2006;48(1):73-9.
2006: Paul M Ridker
Incomplete financial disclosure for study of funding and outcomes in major cardiovascular trials.
JAMA : the journal of the American Medical Association 2006;295(23):2725-6.
2006: Victor Aboyans; Michael H Criqui; Julie O Denenberg; James D Knoke; Paul M Ridker; Arnost Fronek
Risk factors for progression of peripheral arterial disease in large and small vessels.
Circulation 2006;113(22):2623-9.
2006: Debra A Schaumberg; William Christen; Piotr Kozlowski; David T Miller; Paul M Ridker; Robert Y L Zee
A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration.
Investigative ophthalmology & visual science 2006;47(6):2336-40.
2006: S Shrivastava; Paul M Ridker; R J Glynn; Samuel Z Goldhaber; Stephan Moll; H Bounameaux; K A Bauer; C M Kessler; M Cushman
D-dimer, factor VIII coagulant activity, low-intensity warfarin and the risk of recurrent venous thromboembolism.
Journal of thrombosis and haemostasis : JTH 2006;4(6):1208-14.
2006: Paul M Ridker; Jose Torres
Reported outcomes in major cardiovascular clinical trials funded by for-profit and not-for-profit organizations: 2000-2005.
JAMA : the journal of the American Medical Association 2006;295(19):2270-4.
2006: Aileen M Healy; Michael D Pickard; Aruna D Pradhan; Yunmei Wang; Zhiping Chen; Kevin Croce; Masashi Sakuma; Can Shi; Alexandre do Canto Zago; Joseph Garasic; Andrew I Damokosh; Tracy L Dowie; Louis Poisson; James Lillie; Peter Libby; Paul M Ridker; Daniel I Simon
Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events.
Circulation 2006;113(19):2278-84.
2006: Robert Y L Zee; Nancy R Cook; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Paul M Ridker
Polymorphism in the beta2-adrenergic receptor and lipoprotein lipase genes as risk determinants for idiopathic venous thromboembolism: a multilocus, population-based, prospective genetic analysis.
Circulation 2006;113(18):2193-200.
2006: Jessica Rodenburg; Maud N Vissers; Albert Wiegman; Elizabeth R Miller; Paul M Ridker; Joseph L Witztum; John J P Kastelein; Sotirios Tsimikas
Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: effect of pravastatin.
Journal of the American College of Cardiology 2006;47(9):1803-10.
2006: Sotirios Tsimikas; James T Willerson; Paul M Ridker
C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients.
Journal of the American College of Cardiology 2006;47(8 Suppl):C19-31.
2006: Mary McGrae McDermott; Kiang Liu; Jack M Guralnik; Luigi Ferrucci; David Green; Philip Greenland; Lu Tian; Michael H Criqui; Carol Lo; Nader Rifai; Paul M Ridker; Jane Zheng; William Pearce
Functional decline in patients with and without peripheral arterial disease: predictive value of annual changes in levels of C-reactive protein and D-dimer.
The journals of gerontology. Series A, Biological sciences and medical sciences 2006;61(4):374-9.
2006: Daniel I Chasman; Piotr Kozlowski; Robert Y L Zee; David J Kwiatkowski; Paul M Ridker
Qualitative and quantitative effects of APOE genetic variation on plasma C-reactive protein, LDL-cholesterol, and apoE protein.
Genes and immunity 2006;7(3):211-9.
2006: Samia Mora; I-Min Lee; Julie E Buring; Paul M Ridker
Association of physical activity and body mass index with novel and traditional cardiovascular biomarkers in women.
JAMA : the journal of the American Medical Association 2006;295(12):1412-9.
2006: Jennifer Lin; Paul M Ridker; Nader Rifai; I-Min Lee; JoAnn E Manson; Julie E Buring; Shumin M Zhang
A prospective study of hemoglobin A1c concentrations and risk of breast cancer in women.
Cancer research 2006;66(5):2869-75.
2006: Jennifer Weuve; Paul M Ridker; Nancy R Cook; Julie E Buring; Francine Grodstein
High-sensitivity C-reactive protein and cognitive function in older women.
Epidemiology (Cambridge, Mass.) 2006;17(2):183-9.
2006: Robert Y L Zee; Nancy R Cook; S Cheng; Henry A Erlich; Klaus Lindpaintner; Paul M Ridker
Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis.
Journal of thrombosis and haemostasis : JTH 2006;4(2):341-8.
2006: Nan Chiang; Shelley Hurwitz; Paul M Ridker; Charles N Serhan
Aspirin has a gender-dependent impact on antiinflammatory 15-epi-lipoxin A4 formation: a randomized human trial.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(2):e14-7.
2006: Hylton V Joffe; Paul M Ridker; JoAnn E Manson; Nancy R Cook; Julie E Buring; Kathryn M Rexrode
Sex hormone-binding globulin and serum testosterone are inversely associated with C-reactive protein levels in postmenopausal women at high risk for cardiovascular disease.
Annals of epidemiology 2006;16(2):105-12.
2006: Samia Mora; Paul M Ridker
Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER)--can C-reactive protein be used to target statin therapy in primary prevention?
The American journal of cardiology 2006;97(2A):33A-41A.
2006: Chiadi E Ndumele; Aruna D Pradhan; Paul M Ridker
Interrelationships between inflammation, C-reactive protein, and insulin resistance.
Journal of the cardiometabolic syndrome 2006;1(3):190-6.
2005: Jennifer Lin; Paul M Ridker; Aruna Pradhan; I-Min Lee; JoAnn E Manson; Nancy R Cook; Julie E Buring; Shumin M Zhang
Hemoglobin A1c concentrations and risk of colorectal cancer in women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(12):3010-2.
2005: Robert Y L Zee; Hillary H Hegener; Paul M Ridker
Carboxypeptidase B2 gene polymorphisms and the risk of venous thromboembolism.
Journal of thrombosis and haemostasis : JTH 2005;3(12):2819-21.
2005: Mukesh K Jain; Paul M Ridker
Anti-inflammatory effects of statins: clinical evidence and basic mechanisms.
Nature reviews. Drug discovery 2005;4(12):977-87.
2005: Simin Liu; Yiqing Song; Earl S Ford; JoAnn E Manson; Julie E Buring; Paul M Ridker
Dietary calcium, vitamin D, and the prevalence of metabolic syndrome in middle-aged and older U.S. women.
Diabetes care 2005;28(12):2926-32.
2005: Joshua A Beckman; Ori Preis; Paul M Ridker; Marie Gerhard-Herman
Comparison of usefulness of inflammatory markers in patients with versus without peripheral arterial disease in predicting adverse cardiovascular outcomes (myocardial infarction, stroke, and death).
The American journal of cardiology 2005;96(10):1374-8.
2005: Howard D Sesso; Julie E Buring; Marilyn Chown; Paul M Ridker; J Michael Gaziano
A prospective study of plasma lipid levels and hypertension in women.
Archives of internal medicine 2005;165(20):2420-7.
2005: Sanjay Shrivastava; Paul M Ridker
Low dose.
Clinical advances in hematology & oncology : H&O 2005;3(11):880-1.
2005: David T Miller; Robert Y L Zee; J Suk Danik; Piotr Kozlowski; Daniel I Chasman; Ross Lazarus; Nancy R Cook; Paul M Ridker; David J Kwiatkowski
Association of common CRP gene variants with CRP levels and cardiovascular events.
Annals of human genetics 2005;69(Pt 6):623-38.
2005: Sarah A Rosner; Paul M Ridker; Robert Y L Zee; Nancy R Cook
Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the Physician's Health Study.
Human genetics 2005;118(2):287-94.
2005: Kausik K Ray; Christopher P Cannon; Richard Cairns; David A Morrow; Nader Rifai; Ajay J Kirtane; Carolyn H McCabe; Allan M Skene; C Michael Gibson; Paul M Ridker; Eugene Braunwald
Relationship between uncontrolled risk factors and C-reactive protein levels in patients receiving standard or intensive statin therapy for acute coronary syndromes in the PROVE IT-TIMI 22 trial.
Journal of the American College of Cardiology 2005;46(8):1417-24.
2005: Mary McGrae McDermott; Luigi Ferrucci; Kiang Liu; Michael H Criqui; Philip Greenland; David Green; Jack M Guralnik; Paul M Ridker; Lloyd M Taylor; Nader Rifai; Lu Tian; Jane Zheng; William H Pearce; Joseph R Schneider; Ed Vonesh
D-dimer and inflammatory markers as predictors of functional decline in men and women with and without peripheral arterial disease.
Journal of the American Geriatrics Society 2005;53(10):1688-96.
2005: Michelle A Albert; Robert J Glynn; Robert L Wolfert; Paul M Ridker
The effect of statin therapy on lipoprotein associated phospholipase A2 levels.
Atherosclerosis 2005;182(1):193-8.
2005: Paul M Ridker; Nader Rifai; Nancy R Cook; Gary Bradwin; Julie E Buring
Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women.
JAMA : the journal of the American Medical Association 2005;294(3):326-33.
2005: I-Min Lee; Nancy R Cook; J Michael Gaziano; David Gordon; Paul M Ridker; JoAnn E Manson; Charles H Hennekens; Julie E Buring
Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2005;294(1):56-65.
2005: Nancy R Cook; I-Min Lee; J Michael Gaziano; David Gordon; Paul M Ridker; JoAnn E Manson; Charles H Hennekens; Julie E Buring
Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2005;294(1):47-55.
2005: Paul M Ridker
C-reactive protein in 2005. Interview by Peter C. Block.
Journal of the American College of Cardiology 2005;46(1):CS2-5.
2005: Shari S Bassuk; Paul M Ridker; JoAnn E Manson; Julie E Buring
Aspirin and cardiovascular disease prevention in women: new findings from the Women's Health Study.
Women's health (London, England) 2005;1(1):9-10.
2005: Oscar C Marroquin; Kevin Kip; Suresh R Mulukutla; Paul M Ridker; Carl J Pepine; Tjendimin Tjandrawan; Sheryl F Kelsey; Sunil Mankad; William J Rogers; C Noel Bairey Merz; George Sopko; Barry L Sharaf; Steven E Reis
Inflammation, endothelial cell activation, and coronary microvascular dysfunction in women with chest pain and no obstructive coronary artery disease.
American heart journal 2005;150(1):109-15.
2005: Emily B Levitan; Paul M Ridker; JoAnn E Manson; Meir J Stampfer; Julie E Buring; Nancy R Cook; Simin Liu
Association between consumption of beer, wine, and liquor and plasma concentration of high-sensitivity C-reactive protein in women aged 39 to 89 years.
The American journal of cardiology 2005;96(1):83-8.
2005: Robert Y L Zee; Hillary H Hegener; Daniel I Chasman; Paul M Ridker
Tryptophanyl-tRNA synthetase gene polymorphisms and risk of incident myocardial infarction.
Atherosclerosis 2005;181(1):137-41.
2005: Robert D Langer; Aruna D Pradhan; Cora E Lewis; JoAnn E Manson; Jacques E Rossouw; Susan Hendrix; Andrea Z LaCroix; Paul M Ridker
Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women's Health Initiative Observational Study.
Thrombosis and haemostasis 2005;93(6):1108-16.
2005: Yiqing Song; Paul M Ridker; JoAnn E Manson; Nancy R Cook; Julie E Buring; Simin Liu
Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women.
Diabetes care 2005;28(6):1438-44.
2005: Paul M Ridker; David A Morrow; Lynda M Rose; Nader Rifai; Christopher P Cannon; Eugene Braunwald
Relative efficacy of atorvastatin 80 mg and pravastatin 40 mg in achieving the dual goals of low-density lipoprotein cholesterol <70 mg/dl and C-reactive protein <2 mg/l: an analysis of the PROVE-IT TIMI-22 trial.
Journal of the American College of Cardiology 2005;45(10):1644-8.
2005: Debra A Schaumberg; Robert J Glynn; Alicia J Jenkins; Timothy J Lyons; Nader Rifai; JoAnn E Manson; Paul M Ridker; David M Nathan
Effect of intensive glycemic control on levels of markers of inflammation in type 1 diabetes mellitus in the diabetes control and complications trial.
Circulation 2005;111(19):2446-53.
2005: Paul M Ridker; Nancy R Cook; I-Min Lee; David Gordon; J Michael Gaziano; JoAnn E Manson; Charles H Hennekens; Julie E Buring
A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women.
The New England journal of medicine 2005;352(13):1293-304.
2005: Shumin M Zhang; Julie E Buring; I-Min Lee; Nancy R Cook; Paul M Ridker
C-reactive protein levels are not associated with increased risk for colorectal cancer in women.
Annals of internal medicine 2005;142(6):425-32.
2005: Robert Y L Zee; Nancy R Cook; Rebecca Reynolds; Suzanne Cheng; Paul M Ridker
Haplotype analysis of the beta2 adrenergic receptor gene and risk of myocardial infarction in humans.
Genetics 2005;169(3):1583-7.
2005: Paul M Ridker; Nancy Cook
Should age and time be eliminated from cardiovascular risk prediction models? Rationale for the creation of a new national risk detection program.
Circulation 2005;111(5):657-8.
2005: Paul M Ridker; Christopher P Cannon; David Morrow; Nader Rifai; Lynda M Rose; Carolyn H McCabe; Marc A Pfeffer; Eugene Braunwald
C-reactive protein levels and outcomes after statin therapy.
The New England journal of medicine 2005;352(1):20-8.
2005: Paul M Ridker
C-reactive protein, inflammation, and cardiovascular disease: clinical update.
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 2005;32(3):384-6.
2005: Subodh Verma; Paul E Szmitko; Paul M Ridker
C-reactive protein comes of age.
Nature clinical practice. Cardiovascular medicine 2005;2(1):29-36; quiz 58.
2005: Daniel I Chasman; Paul M Ridker
Pharmacogenetics: the outlook for genetic testing in statin therapy.
Nature clinical practice. Cardiovascular medicine 2005;2(1):2-3.
2005: H Jacqueline Suk; Paul M Ridker; Nancy R Cook; Robert Y L Zee
Relation of polymorphism within the C-reactive protein gene and plasma CRP levels.
Atherosclerosis 2005;178(1):139-45.
2005: Robert Y L Zee; Hillary H Hegener; Jessica Gould; Paul M Ridker
Toll-like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis.
Stroke; a journal of cerebral circulation 2005;36(1):154-7.
2004: Sidney C Smith; Jeffrey L Anderson; Richard O Cannon; Yazid Y Fadl; Wolfgang Koenig; Peter Libby; Steven E Lipshultz; George Mensah; Paul M Ridker; Robert S Rosenson
CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: report from the clinical practice discussion group.
Circulation 2004;110(25):e550-3.
2004: Marguerite M Engler; Mary B Engler; Mary J Malloy; E Chiu; D Besio; S Paul; Markus Stuehlinger; J Morrow; Paul M Ridker; Nader Rifai; Michele L Mietus-Snyder
Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study.
International journal of clinical pharmacology and therapeutics 2004;42(12):672-9.
2004: Mary McGrae McDermott; Jack M Guralnik; Philip Greenland; David Green; Kiang Liu; Paul M Ridker; Cheeling Chan; Michael H Criqui; Luigi Ferrucci; Lloyd M Taylor; William H Pearce; Joseph R Schneider; Sarah I Oskin
Inflammatory and thrombotic blood markers and walking-related disability in men and women with and without peripheral arterial disease.
Journal of the American Geriatrics Society 2004;52(11):1888-94.
2004: Nan Chiang; Edmund A Bermudez; Paul M Ridker; Shelley Hurwitz; Charles N Serhan
Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(42):15178-83.
2004: Robert Y L Zee; Hillary H Hegener; Nancy R Cook; Paul M Ridker
C-reactive protein gene polymorphisms and the risk of venous thromboembolism: a haplotype-based analysis.
Journal of thrombosis and haemostasis : JTH 2004;2(8):1240-3.
2004: Shari S Bassuk; Nader Rifai; Paul M Ridker
High-sensitivity C-reactive protein: clinical importance.
Current problems in cardiology 2004;29(8):439-93.
2004: Nader Rifai; Jing Ma; Frank M Sacks; Paul M Ridker; Wendy Jade L Hernandez; Meir J Stampfer; Santica M Marcovina
Apolipoprotein(a) size and lipoprotein(a) concentration and future risk of angina pectoris with evidence of severe coronary atherosclerosis in men: The Physicians' Health Study.
Clinical chemistry 2004;50(8):1364-71.
2004: Aruna D Pradhan; Andrea Z LaCroix; Robert D Langer; Maurizio Trevisan; Cora E Lewis; Judith A Hsia; Albert Oberman; Jane Morley Kotchen; Paul M Ridker
Tissue plasminogen activator antigen and D-dimer as markers for atherothrombotic risk among healthy postmenopausal women.
Circulation 2004;110(3):292-300.
2004: Paul M Ridker; Wolfgang Koenig; Valentin Fuster
C-reactive protein and coronary heart disease.
The New England journal of medicine 2004;351(3):295-8; author reply 295-8.
2004: Michelle A Albert; Jose Torres; Robert J Glynn; Paul M Ridker
Perspective on selected issues in cardiovascular disease research with a focus on black Americans.
Circulation 2004;110(2):e7-12.
2004: Paul M Ridker
Long-term low-dose warfarin use is effective in the prevention of recurrent venous thromboembolism: yes.
Journal of thrombosis and haemostasis : JTH 2004;2(7):1034-7.
2004: Paul M Ridker
High-sensitivity C-reactive protein, inflammation, and cardiovascular risk: from concept to clinical practice to clinical benefit.
American heart journal 2004;148(1 Suppl):S19-26.
2004: Robert Y L Zee; Nancy R Cook; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Richard T Lee; Paul M Ridker
Threonine for alanine substitution in the eotaxin (CCL11) gene and the risk of incident myocardial infarction.
Atherosclerosis 2004;175(1):91-4.
2004: Paul M Ridker; Nancy Brown; Douglas E Vaughan; David G Harrison; Jawahar L Mehta
Established and emerging plasma biomarkers in the prediction of first atherothrombotic events.
Circulation 2004;109(25 Suppl 1):IV6-19.
2004: Meir J Stampfer; Paul M Ridker; Victor J Dzau
Risk factor criteria.
Circulation 2004;109(25 Suppl 1):IV3-5.
2004: Daniel I Chasman; David Posada; Lakshman Subrahmanyan; Nancy R Cook; Vincent P Stanton; Paul M Ridker
Pharmacogenetic study of statin therapy and cholesterol reduction.
JAMA : the journal of the American Medical Association 2004;291(23):2821-7.
2004: Paul M Ridker; Peter W F Wilson; Scott M Grundy
Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?
Circulation 2004;109(23):2818-25.
2004: James T Willerson; Paul M Ridker
Inflammation as a cardiovascular risk factor.
Circulation 2004;109(21 Suppl 1):II2-10.
2004: Sidney C Smith; Richard V Milani; Donna K Arnett; John R Crouse; Mary McGrae McDermott; Paul M Ridker; Robert S Rosenson; Kathryn A Taubert; Peter W F Wilson
Atherosclerotic Vascular Disease Conference: Writing Group II: risk factors.
Circulation 2004;109(21):2613-6.
2004: Michelle A Albert; Robert J Glynn; Julie E Buring; Paul M Ridker
C-reactive protein levels among women of various ethnic groups living in the United States (from the Women's Health Study).
The American journal of cardiology 2004;93(10):1238-42.
2004: Nancy R Cook; Robert Y L Zee; Paul M Ridker
Tree and spline based association analysis of gene-gene interaction models for ischemic stroke.
Statistics in medicine 2004;23(9):1439-53.
2004: Christopher S Coffey; Patricia R Hebert; Marylyn Ritchie; Harlan Krumholz; J Michael Gaziano; Paul M Ridker; Nancy J Brown; Douglas E Vaughan; Jason Moore
An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation.
BMC bioinformatics 2004;5():49.
2004: Paul M Ridker; Nancy Cook
Clinical usefulness of very high and very low levels of C-reactive protein across the full range of Framingham Risk Scores.
Circulation 2004;109(16):1955-9.
2004: Gavin J Blake; Aruna D Pradhan; JoAnn E Manson; G Rhys Williams; Julie E Buring; Paul M Ridker; Robert J Glynn
Hemoglobin A1c level and future cardiovascular events among women.
Archives of internal medicine 2004;164(7):757-61.
2004: Peter J Mason; JoAnn E Manson; Howard D Sesso; Christine M Albert; Marilyn Chown; Nancy R Cook; Philip Greenland; Paul M Ridker; Robert J Glynn
Blood pressure and risk of secondary cardiovascular events in women: the Women's Antioxidant Cardiovascular Study (WACS).
Circulation 2004;109(13):1623-9.
2004: Steve E Humphries; Paul M Ridker; Philippa J Talmud
Genetic testing for cardiovascular disease susceptibility: a useful clinical management tool or possible misinformation?
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):628-36.
2004: Peter Libby; Paul M Ridker
Inflammation and atherosclerosis: role of C-reactive protein in risk assessment.
The American journal of medicine 2004;116 Suppl 6A():9S-16S.
2004: Lynn L Amowitz; Paul M Ridker; Nadir Rifai; Clodagh M Loughrey; Anthony L Komaroff
High prevalence of metabolic syndrome among young women with nonfatal myocardial infarction.
Journal of women's health (2002) 2004;13(2):165-75; discussion 175.
2004: Craig R Narins; Wojciech Zareba; Arthur J Moss; Victor J Marder; Paul M Ridker; Ronald J Krone; Edgar Lichstein
Relationship between intermittent claudication, inflammation, thrombosis, and recurrent cardiac events among survivors of myocardial infarction.
Archives of internal medicine 2004;164(4):440-6.
2004: Hans K Meier-Ewert; Paul M Ridker; Nader Rifai; Meredith M Regan; Nick J Price; David F Dinges; Janet M Mullington
Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk.
Journal of the American College of Cardiology 2004;43(4):678-83.
2004: B Delia Johnson; Kevin Kip; Oscar C Marroquin; Paul M Ridker; Sheryl F Kelsey; Leslee J Shaw; Carl J Pepine; Barry L Sharaf; C Noel Bairey-Merz; George Sopko; Marian B Olson; Steven E Reis
Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women: the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Circulation 2004;109(6):726-32.
2004: Robert Y L Zee; Nancy R Cook; Suzanne Cheng; Rebecca Reynolds; Henry A Erlich; Klaus Lindpaintner; Paul M Ridker
Polymorphism in the P-selectin and interleukin-4 genes as determinants of stroke: a population-based, prospective genetic analysis.
Human molecular genetics 2004;13(4):389-96.
2004: Robert Y L Zee; Paul M Ridker; Nancy R Cook
Prospective evaluation of the alcohol dehydrogenase gamma1/gamma2 gene polymorphism and risk of stroke.
Stroke; a journal of cerebral circulation 2004;35(2):e39-42.
2004: Michelle A Albert; Robert J Glynn; Paul M Ridker
Effect of physical activity on serum C-reactive protein.
The American journal of cardiology 2004;93(2):221-5.
2004: Paul M Ridker
Inflammation in atherothrombosis: how to use high-sensitivity C-reactive protein (hsCRP) in clinical practice.
The American heart hospital journal 2004;2(4 Suppl 1):4-9.
2004: Michelle A Albert; Paul M Ridker
Inflammatory biomarkers in African Americans: a potential link to accelerated atherosclerosis.
Reviews in cardiovascular medicine 2004;5 Suppl 3():S22-7.
2003: Gavin J Blake; Nader Rifai; Julie E Buring; Paul M Ridker
Blood pressure, C-reactive protein, and risk of future cardiovascular events.
Circulation 2003;108(24):2993-9.
2003: Howard D Sesso; Julie E Buring; Nader Rifai; Gavin J Blake; J Michael Gaziano; Paul M Ridker
C-reactive protein and the risk of developing hypertension.
JAMA : the journal of the American Medical Association 2003;290(22):2945-51.
2003: James P Corsetti; Wojciech Zareba; Arthur J Moss; Paul M Ridker; Victor J Marder; David L Rainwater; Charles E Sparks
Metabolic syndrome best defines the multivariate distribution of blood variables in postinfarction patients.
Atherosclerosis 2003;171(2):351-8.
2003: Paul M Ridker; Samuel Z Goldhaber; Robert J Glynn
Low-intensity versus conventional-intensity warfarin for prevention of recurrent venous thromboembolism.
The New England journal of medicine 2003;349(22):2164-7; author reply 2164-7.
2003: Paul M Ridker
Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: rationale and design of the JUPITER trial.
Circulation 2003;108(19):2292-7.
2003: Kathryn M Rexrode; Aruna Pradhan; JoAnn E Manson; Julie E Buring; Paul M Ridker
Relationship of total and abdominal adiposity with CRP and IL-6 in women.
Annals of epidemiology 2003;13(10):674-82.
2003: José L Torres; Paul M Ridker
Clinical use of high sensitivity C-reactive protein for the prediction of adverse cardiovascular events.
Current opinion in cardiology 2003;18(6):471-8.
2003: Gavin J Blake; Paul M Ridker
C-reactive protein: a surrogate risk marker or mediator of atherothrombosis?
American journal of physiology. Regulatory, integrative and comparative physiology 2003;285(5):R1250-2.
2003: Kathryn M Rexrode; JoAnn E Manson; I-Min Lee; Paul M Ridker; patrick sluss; Nancy R Cook; Julie E Buring
Sex hormone levels and risk of cardiovascular events in postmenopausal women.
Circulation 2003;108(14):1688-93.
2003: Gavin J Blake; Michelle A Albert; Nader Rifai; Paul M Ridker
Effect of pravastatin on LDL particle concentration as determined by NMR spectroscopy: a substudy of a randomized placebo controlled trial.
European heart journal 2003;24(20):1843-7.
2003: Paul M Ridker
Cardiology Patient Page. C-reactive protein: a simple test to help predict risk of heart attack and stroke.
Circulation 2003;108(12):e81-5.
2003: Marguerite M Engler; Mary B Engler; Mary J Malloy; Elisa Y Chiu; Monique C Schloetter; Steven M Paul; Markus Stuehlinger; Ken Y Lin; john cooke; Jason D Morrow; Paul M Ridker; Nader Rifai; Elizabeth Miller; Joseph L Witztum; Michele L Mietus-Snyder
Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial.
Circulation 2003;108(9):1059-63.
2003: Paul M Ridker; Shari S Bassuk; Peter P. Toth
C-reactive protein and risk of cardiovascular disease: evidence and clinical application.
Current atherosclerosis reports 2003;5(5):341-9.
2003: Paul M Ridker
High-sensitivity C-reactive protein and cardiovascular risk: rationale for screening and primary prevention.
The American journal of cardiology 2003;92(4B):17K-22K.
2003: Paul M Ridker; David A Morrow
C-reactive protein, inflammation, and coronary risk.
Cardiology clinics 2003;21(3):315-25.
2003: Earl S Ford; Wayne H Giles; Gary L Myers; Nader Rifai; Paul M Ridker; David M Mannino
C-reactive protein concentration distribution among US children and young adults: findings from the National Health and Nutrition Examination Survey, 1999-2000.
Clinical chemistry 2003;49(8):1353-7.
2003: Mary McGrae McDermott; David Green; Philip Greenland; Kiang Liu; Michael H Criqui; Cheeling Chan; Jack M Guralnik; William H Pearce; Paul M Ridker; Lloyd M Taylor; Nader Rifai; Joseph R Schneider
Relation of levels of hemostatic factors and inflammatory markers to the ankle brachial index.
The American journal of cardiology 2003;92(2):194-9.
2003: Michelle A Albert; Robert J Glynn; Paul M Ridker
Plasma concentration of C-reactive protein and the calculated Framingham Coronary Heart Disease Risk Score.
Circulation 2003;108(2):161-5.
2003: Mary McGrae McDermott; Philip Greenland; David Green; Jack M Guralnik; Michael H Criqui; Kiang Liu; Cheeling Chan; William H Pearce; Lloyd M Taylor; Paul M Ridker; Joseph R Schneider; Gary Martin; Nader Rifai; Maureen Quann; Myriam Fornage
D-dimer, inflammatory markers, and lower extremity functioning in patients with and without peripheral arterial disease.
Circulation 2003;107(25):3191-8.
2003: Tareq S Harb; Wojciech Zareba; Arthur J Moss; Paul M Ridker; Nader Rifai; Victor J Marder; Luc F Miller Watelet
Association between inflammatory markers, hemostatic, and lipid factors in postinfarction patients.
The American journal of cardiology 2003;91(9):1120-3.
2003: Paul M Ridker; Nancy R Cook; Suzanne Cheng; Henry A Erlich; Klaus Lindpaintner; Jorge Plutzky; Robert Y L Zee
Alanine for proline substitution in the peroxisome proliferator-activated receptor gamma-2 (PPARG2) gene and the risk of incident myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(5):859-63.
2003: Gavin J Blake; Paul M Ridker; Karen M Kuntz
Potential cost-effectiveness of C-reactive protein screening followed by targeted statin therapy for the primary prevention of cardiovascular disease among patients without overt hyperlipidemia.
The American journal of medicine 2003;114(6):485-94.
2003: Aruna D Pradhan; JoAnn E Manson; James B Meigs; Nader Rifai; Julie E Buring; Simin Liu; Paul M Ridker
Insulin, proinsulin, proinsulin:insulin ratio, and the risk of developing type 2 diabetes mellitus in women.
The American journal of medicine 2003;114(6):438-44.
2003: Paul M Ridker; Samuel Z Goldhaber; Ellie Danielson; Yves Rosenberg; Charles S Eby; Steven R Deitcher; Mary Cushman; Stephan Moll; Craig M Kessler; C Gregory Elliott; Rolf Paulson; Turnly Wong; Kenneth A Bauer; Bruce A Schwartz; Joseph P Miletich; Henri Bounameaux; Robert J Glynn
Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism.
The New England journal of medicine 2003;348(15):1425-34.
2003: Paul M Ridker
Connecting the role of C-reactive protein and statins in cardiovascular disease.
Clinical cardiology 2003;26(4 Suppl 3):III39-44.
2003: Aruna D Pradhan; Nancy R Cook; Julie E Buring; JoAnn E Manson; Paul M Ridker
C-reactive protein is independently associated with fasting insulin in nondiabetic women.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(4):650-5.
2003: Nader Rifai; Paul M Ridker
Population distributions of C-reactive protein in apparently healthy men and women in the United States: implication for clinical interpretation.
Clinical chemistry 2003;49(4):666-9.
2003: Gavin J Blake; Paul M Ridker
C-reactive protein and other inflammatory risk markers in acute coronary syndromes.
Journal of the American College of Cardiology 2003;41(4 Suppl S):37S-42S.
2003: Mary McGrae McDermott; Jack M Guralnik; Philip Greenland; William H Pearce; Michael H Criqui; Kiang Liu; Lloyd M Taylor; Cheeling Chan; Leena Sharma; Joseph R Schneider; Paul M Ridker; David Green; Maureen Quann
Statin use and leg functioning in patients with and without lower-extremity peripheral arterial disease.
Circulation 2003;107(5):757-61.
2003: Simin Liu; Jing Ma; Paul M Ridker; Jan L Breslow; Meir J Stampfer
A prospective study of the association between APOE genotype and the risk of myocardial infarction among apparently healthy men.
Atherosclerosis 2003;166(2):323-9.
2003: Michelle A Albert; Robert J Glynn; Paul M Ridker
Alcohol consumption and plasma concentration of C-reactive protein.
Circulation 2003;107(3):443-7.
2003: Paul M Ridker; Julie E Buring; Nancy R Cook; Nader Rifai
C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women.
Circulation 2003;107(3):391-7.
2003: Paul M Ridker
Clinical application of C-reactive protein for cardiovascular disease detection and prevention.
Circulation 2003;107(3):363-9.
2003: José L Torres; Paul M Ridker
High sensitivity C-reactive protein in clinical practice.
The American heart hospital journal 2003;1(3):207-11.
2003: Gavin J Blake; Robert J Ostfeld; E Kent Yucel; Nerea Varo; Uwe Schönbeck; Michael A Blake; Marie Gerhard; Paul M Ridker; Peter Libby; Richard T Lee
Soluble CD40 ligand levels indicate lipid accumulation in carotid atheroma: an in vivo study with high-resolution MRI.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(1):e11-4.
2002: Paul M Ridker; Nader Rifai; Lynda Rose; Julie E Buring; Nancy R Cook
Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events.
The New England journal of medicine 2002;347(20):1557-65.
2002: Gavin J Blake; James D Otvos; Nader Rifai; Paul M Ridker
Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in women.
Circulation 2002;106(15):1930-7.
2002: Edmund A Bermudez; Nader Rifai; Julie E Buring; JoAnn E Manson; Paul M Ridker
Interrelationships among circulating interleukin-6, C-reactive protein, and traditional cardiovascular risk factors in women.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(10):1668-73.
2002: Gavin J Blake; Paul M Ridker
C-reactive protein, subclinical atherosclerosis, and risk of cardiovascular events.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(10):1512-3.
2002: Jennifer K Pai; Gary C Curhan; Carolyn C Cannuscio; Nader Rifai; Paul M Ridker; Eric B Rimm
Stability of novel plasma markers associated with cardiovascular disease: processing within 36 hours of specimen collection.
Clinical chemistry 2002;48(10):1781-4.
2002: Andrew D Blann; Paul M Ridker; Gregory Y H Lip
Inflammation, cell adhesion molecules, and stroke: tools in pathophysiology and epidemiology?
Stroke; a journal of cerebral circulation 2002;33(9):2141-3.
2002: Aruna D Pradhan; JoAnn E Manson; Jacques E Rossouw; David S Siscovick; Charles P Mouton; Nader Rifai; Robert B Wallace; Rebecca D Jackson; Mary Pettinger; Paul M Ridker
Inflammatory biomarkers, hormone replacement therapy, and incident coronary heart disease: prospective analysis from the Women's Health Initiative observational study.
JAMA : the journal of the American Medical Association 2002;288(8):980-7.
2002: Aruna D Pradhan; Nader Rifai; Paul M Ridker
Soluble intercellular adhesion molecule-1, soluble vascular adhesion molecule-1, and the development of symptomatic peripheral arterial disease in men.
Circulation 2002;106(7):820-5.
2002: Nader Rifai; Paul M Ridker
Inflammatory markers and coronary heart disease.
Current opinion in lipidology 2002;13(4):383-9.
2002: Gavin J Blake; Paul M Ridker; Karen M Kuntz
Projected life-expectancy gains with statin therapy for individuals with elevated C-reactive protein levels.
Journal of the American College of Cardiology 2002;40(1):49-55.
2002: David A Brown; Samuel N Breit; Julie E Buring; W Douglas Fairlie; Asne R Bauskin; Tao Liu; Paul M Ridker
Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study.
Lancet 2002;359(9324):2159-63.
2002: Christine M Albert; Jing Ma; Nader Rifai; Meir J Stampfer; Paul M Ridker
Prospective study of C-reactive protein, homocysteine, and plasma lipid levels as predictors of sudden cardiac death.
Circulation 2002;105(22):2595-9.
2002: Paul M Ridker
Inflammatory biomarkers, statins, and the risk of stroke: cracking a clinical conundrum.
Circulation 2002;105(22):2583-5.
2002: Scott Kinlay; Tracy Timms; Maureen Clark; Carolina Karam; Tim Bilodeau; Paul M Ridker; Nader Rifai; William Carlson; Donald M Lloyd-Jones; Michael Johnstone; Joel Rubenstein; Sidney Alexander; John Orav; Peter H Stone
Comparison of effect of intensive lipid lowering with atorvastatin to less intensive lowering with lovastatin on C-reactive protein in patients with stable angina pectoris and inducible myocardial ischemia.
The American journal of cardiology 2002;89(10):1205-7.
2002: Arthur J Siegel; Jack H Mendelson; Michelle B Sholar; Jane C McDonald; Kent B Lewandrowski; Elizabeth Lee Lewandrowski; Izabella Lipinska; Paul M Ridker; Geoffrey H Tofler
Effect of cocaine usage on C-reactive protein, von Willebrand factor, and fibrinogen.
The American journal of cardiology 2002;89(9):1133-5.
2002: Edmund A Bermudez; Nader Rifai; Julie E Buring; JoAnn E Manson; Paul M Ridker
Relation between markers of systemic vascular inflammation and smoking in women.
The American journal of cardiology 2002;89(9):1117-9.
2002: Robert Y L Zee; Paul M Ridker
Polymorphism in the human C-reactive protein (CRP) gene, plasma concentrations of CRP, and the risk of future arterial thrombosis.
Atherosclerosis 2002;162(1):217-9.
2002: Paul M Ridker; Jessie Shih; Thomas J Cook; Michael Clearfield; John R Downs; Aruna D Pradhan; Stephan E Weis; Antonio M Gotto
Plasma homocysteine concentration, statin therapy, and the risk of first acute coronary events.
Circulation 2002;105(15):1776-9.
2002: Christine M Albert; HANNIA CAMPOS; Meir J Stampfer; Paul M Ridker; JoAnn E Manson; Walter C Willett; Jing Ma
Blood levels of long-chain n-3 fatty acids and the risk of sudden death.
The New England journal of medicine 2002;346(15):1113-8.
2002: Nader Rifai; Julie E Buring; I-Min Lee; JoAnn E Manson; Paul M Ridker
Is C-reactive protein specific for vascular disease in women?
Annals of internal medicine 2002;136(7):529-33.
2002: Robert Y L Zee; David Bates; Paul M Ridker
A prospective evaluation of the heat shock protein 70 gene polymorphisms and the risk of stroke.
Thrombosis and haemostasis 2002;87(4):622-5.
2002: Robert Y L Zee; David Bates; Paul M Ridker
A prospective evaluation of the CD14 and CD18 gene polymorphisms and risk of stroke.
Stroke; a journal of cerebral circulation 2002;33(4):892-5.
2002: Simin Liu; Christian Schmitz; Meir J Stampfer; Frank Sacks; Charles H Hennekens; Klaus Lindpaintner; Paul M Ridker; Simm Liu
A prospective study of TaqIB polymorphism in the gene coding for cholesteryl ester transfer protein and risk of myocardial infarction in middle-aged men.
Atherosclerosis 2002;161(2):469-74.
2002: Peter Libby; Paul M Ridker; Attilio Maseri
Inflammation and atherosclerosis.
Circulation 2002;105(9):1135-43.
2002: Simin Liu; JoAnn E Manson; Julie E Buring; Meir J Stampfer; Walter C Willett; Paul M Ridker
Relation between a diet with a high glycemic load and plasma concentrations of high-sensitivity C-reactive protein in middle-aged women.
The American journal of clinical nutrition 2002;75(3):492-8.
2002: Rachel S Eidelman; Gervasio A Lamas; Charles H Hennekens; Paul M Ridker
Aspirin, postmenopausal hormones, and C-reactive protein.
Archives of internal medicine 2002;162(4):480-1.
2002: Tareq S Harb; Wojciech Zareba; Arthur J Moss; Paul M Ridker; Victor J Marder; Nader Rifai; Luc F Miller Watelet; Rohit Arora; Mary W Brown; Robert B Case; Edward M Dwyer; John A Gillespie; Robert E Goldstein; Henry Greenberg; Judith S Hochman; Ronald J Krone; Chang-seng Liang; Edgar Lichstein; William Little; Frank I Marcus; David Oakes; Charles E Sparks; Lucy VanVoorhees
Association of C-reactive protein and serum amyloid A with recurrent coronary events in stable patients after healing of acute myocardial infarction.
The American journal of cardiology 2002;89(2):216-21.
2002: Paul M Ridker
Inherited risk factors for venous thromboembolism: implications for clinical practice.
Clinical cornerstone 2002;4(6):18-30.
2002: Edmund A Bermudez; Paul M Ridker
C-reactive protein, statins, and the primary prevention of atherosclerotic cardiovascular disease.
Preventive cardiology 2002;5(1):42-6.
2002: Paul M Ridker
On evolutionary biology, inflammation, infection, and the causes of atherosclerosis.
Circulation 2002;105(1):2-4.
2001: Uwe Schönbeck; Nerea Varo; Peter Libby; Julie E Buring; Paul M Ridker
Soluble CD40L and cardiovascular risk in women.
Circulation 2001;104(19):2266-8.
2001: Robert Y L Zee; K Lunze; Klaus Lindpaintner; Paul M Ridker
A prospective evaluation of the interleukin-1 receptor antagonist intron 2 gene polymorphism and the risk of myocardial infarction.
Thrombosis and haemostasis 2001;86(5):1141-3.
2001: Gavin J Blake; Paul M Ridker
Inflammatory mechanisms in atherosclerosis: from laboratory evidence to clinical application.
Italian heart journal : official journal of the Italian Federation of Cardiology 2001;2(11):796-800.
2001: Gavin J Blake; N Dada; J C Fox; JoAnn E Manson; Paul M Ridker
A prospective evaluation of lipoprotein-associated phospholipase A(2) levels and the risk of future cardiovascular events in women.
Journal of the American College of Cardiology 2001;38(5):1302-6.
2001: Arthur J Siegel; JJ Stec; Izabella Lipinska; Elizabeth M Van Cott; Kent B Lewandrowski; Paul M Ridker; Geoffrey H Tofler
Effect of marathon running on inflammatory and hemostatic markers.
The American journal of cardiology 2001;88(8):918-20, A9.
2001: Paul M Ridker
Role of inflammatory biomarkers in prediction of coronary heart disease.
Lancet 2001;358(9286):946-8.
2001: Claudia U Chae; Richard T Lee; Nader Rifai; Paul M Ridker
Blood pressure and inflammation in apparently healthy men.
Hypertension 2001;38(3):399-403.
2001: Paul M Ridker; J Danesh; Linda Youngman; R Collins; Meir J Stampfer; R Peto; Charles H Hennekens
A prospective study of Helicobacter pylori seropositivity and the risk for future myocardial infarction among socioeconomically similar U.S. men.
Annals of internal medicine 2001;135(3):184-8.
2001: Michelle A Albert; E Danielson; Nader Rifai; Paul M Ridker
Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study.
JAMA : the journal of the American Medical Association 2001;286(1):64-70.
2001: Paul M Ridker; Nader Rifai; Michael Clearfield; J R Downs; S E Weis; J S Miles; Antonio M Gotto
Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events.
The New England journal of medicine 2001;344(26):1959-65.
2001: Michelle A Albert; J Staggers; P Chew; Paul M Ridker
The pravastatin inflammation CRP evaluation (PRINCE): rationale and design.
American heart journal 2001;141(6):893-8.
2001: Paul M Ridker; Meir J Stampfer; Nader Rifai
Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease.
JAMA : the journal of the American Medical Association 2001;285(19):2481-5.
2001: Paul M Ridker
High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease.
Circulation 2001;103(13):1813-8.
2001: Paul M Ridker; Nader Rifai; S P Lowenthal
Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia.
Circulation 2001;103(9):1191-3.
2001: Hans K Meier-Ewert; Paul M Ridker; Nader Rifai; N Price; David F Dinges; Janet M Mullington
Absence of diurnal variation of C-reactive protein concentrations in healthy human subjects.
Clinical chemistry 2001;47(3):426-30.
2001: Nader Rifai; Paul M Ridker
High-sensitivity C-reactive protein: a novel and promising marker of coronary heart disease.
Clinical chemistry 2001;47(3):403-11.
2001: Lisa M Hines; Meir J Stampfer; Jing Ma; J Michael Gaziano; Paul M Ridker; Susan E Hankinson; Frank M Sacks; Eric B Rimm; David J Hunter
Genetic variation in alcohol dehydrogenase and the beneficial effect of moderate alcohol consumption on myocardial infarction.
The New England journal of medicine 2001;344(8):549-55.
2001: R Y Zee; Klaus Lindpaintner; Berthold Struk; C H Hennekens; Paul M Ridker
A prospective evaluation of the CD14 C(-260)T gene polymorphism and the risk of myocardial infarction.
Atherosclerosis 2001;154(3):699-702.
2001: T H Howell; Paul M Ridker; Umed Ajani; Charles H Hennekens; William Christen
Periodontal disease and risk of subsequent cardiovascular disease in U.S. male physicians.
Journal of the American College of Cardiology 2001;37(2):445-50.
2001: Paul M Ridker; Julie E Buring; Nader Rifai
Soluble P-selectin and the risk of future cardiovascular events.
Circulation 2001;103(4):491-5.
2001: Michelle A Albert; Nader Rifai; Paul M Ridker
Plasma levels of cystatin-C and mannose binding protein are not associated with risk of developing systemic atherosclerosis.
Vascular medicine (London, England) 2001;6(3):145-9.
2001: Nader Rifai; Paul M Ridker
Proposed cardiovascular risk assessment algorithm using high-sensitivity C-reactive protein and lipid screening.
Clinical chemistry 2001;47(1):28-30.
2000: James A de Lemos; Charles H Hennekens; Paul M Ridker
Plasma concentration of soluble vascular cell adhesion molecule-1 and subsequent cardiovascular risk.
Journal of the American College of Cardiology 2000;36(2):423-6.
2000: Paul M Ridker
Are statins anti-inflammatory? Issues in the design and conduct of the pravastatin inflammation C-reactive protein evaluation.
Current cardiology reports 2000;2(4):269-73.
2000: Rita F Redberg; Nader Rifai; L Gee; Paul M Ridker
Lack of association of C-reactive protein and coronary calcium by electron beam computed tomography in postmenopausal women: implications for coronary artery disease screening.
Journal of the American College of Cardiology 2000;36(1):39-43.
2000: W G Christen; Paul M Ridker
Blood levels of homocysteine and atherosclerotic vascular disease.
Current atherosclerosis reports 2000;2(3):194-9.
2000: Paul M Ridker; Nader Rifai; Meir J Stampfer; Charles H Hennekens
Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men.
Circulation 2000;101(15):1767-72.
2000: Paul M Ridker; Charles H Hennekens; Julie E Buring; Nader Rifai
C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women.
The New England journal of medicine 2000;342(12):836-43.
2000: Paul M Ridker
Inherited risk factors for venous thromboembolism: implications for clinical practice.
Clinical cornerstone 2000;2(4):1-14.
2000: Paul M Ridker
Novel risk factors and markers for coronary disease.
Advances in internal medicine 2000;45():391-418.
1999: Nader Rifai; R P Tracy; Paul M Ridker
Clinical efficacy of an automated high-sensitivity C-reactive protein assay.
Clinical chemistry 1999;45(12):2136-41.
1999: Guo-Ping Shi; Galina K Sukhova; A Grubb; A Ducharme; L H Rhode; Richard T Lee; Paul M Ridker; Peter Libby; Harold A Chapman
Cystatin C deficiency in human atherosclerosis and aortic aneurysms.
The Journal of clinical investigation 1999;104(9):1191-7.
1999: S Rubattu; Paul M Ridker; Meir J Stampfer; M Volpe; Charles H Hennekens; Klaus Lindpaintner
The gene encoding atrial natriuretic peptide and the risk of human stroke.
Circulation 1999;100(16):1722-6.
1999: Paul M Ridker; Charles H Hennekens; J E Buring; R Kundsin; J Shih
Baseline IgG antibody titers to Chlamydia pneumoniae, Helicobacter pylori, herpes simplex virus, and cytomegalovirus and the risk for cardiovascular disease in women.
Annals of internal medicine 1999;131(8):573-7.
1999: Paul M Ridker; Elliott M Antman
Pathogenesis and pathology of coronary heart disease syndromes.
Journal of thrombosis and thrombolysis 1999;8(3):167-89.
1999: Arthur J Siegel; Michelle B Sholar; Jack H Mendelson; Scott E Lukas; Marc J Kaufman; Perry F Renshaw; Jane C McDonald; Kent B Lewandrowski; F S Apple; JJ Stec; Izabella Lipinska; Geoffrey H Tofler; Paul M Ridker
Cocaine-induced erythrocytosis and increase in von Willebrand factor: evidence for drug-related blood doping and prothrombotic effects.
Archives of internal medicine 1999;159(16):1925-9.
1999: Paul M Ridker; Charles H Hennekens; Nader Rifai; Julie E Buring; JoAnn E Manson
Hormone replacement therapy and increased plasma concentration of C-reactive protein.
Circulation 1999;100(7):713-6.
1999: Paul M Ridker; Nader Rifai; Marc A Pfeffer; Frank M Sacks; Eugene Braunwald
Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators.
Circulation 1999;100(3):230-5.
1999: M A Albert; Paul M Ridker
The role of C-reactive protein in cardiovascular disease risk.
Current cardiology reports 1999;1(2):99-104.
1999: Luis E Rohde; LH Arroyo; Nader Rifai; MA Creager; Peter Libby; Paul M Ridker; Richard T Lee
Plasma concentrations of interleukin-6 and abdominal aortic diameter among subjects without aortic dilatation.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(7):1695-9.
1999: Luis E Rohde; Charles H Hennekens; Paul M Ridker
Cross-sectional study of soluble intercellular adhesion molecule-1 and cardiovascular risk factors in apparently healthy men.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(7):1595-9.
1999: Paul M Ridker
Evaluating novel cardiovascular risk factors: can we better predict heart attacks?
Annals of internal medicine 1999;130(11):933-7.
1999: Paul M Ridker; Charles H Hennekens; JP Miletich
G20210A mutation in prothrombin gene and risk of myocardial infarction, stroke, and venous thrombosis in a large cohort of US men.
Circulation 1999;99(8):999-1004.
1999: Paul M Ridker; Meir J Stampfer
Assessment of genetic markers for coronary thrombosis: promise and precaution.
Lancet 1999;353(9154):687-8.
1999: Lynn L Amowitz; A L Komaroff; J P Miletich; Paul M Ridker
Factor V Leiden is not a risk factor for myocardial infarction among young women.
Blood 1999;93(4):1432-3.
1999: Robert Y L Zee; Paul M Ridker; Meir J Stampfer; Charles H Hennekens; Klaus Lindpaintner
Prospective evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of stroke.
Circulation 1999;99(3):340-3.
1998: Paul M Ridker; Charles H Hennekens; Meir J Stampfer; F Wang
Prospective study of herpes simplex virus, cytomegalovirus, and the risk of future myocardial infarction and stroke.
Circulation 1998;98(25):2796-9.
1998: Luis E Rohde; Richard T Lee; J Rivero; M Jamacochian; LH Arroyo; W Briggs; Nader Rifai; Peter Libby; MA Creager; Paul M Ridker
Circulating cell adhesion molecules are correlated with ultrasound-based assessment of carotid atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(11):1765-70.
1998: Paul M Ridker; Nader Rifai; Marc A Pfeffer; Frank M Sacks; L A Moye; S Goldman; Greg C Flaker; Eugene Braunwald
Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events (CARE) Investigators.
Circulation 1998;98(9):839-44.
1998: Paul M Ridker; J P Miletich; J E Buring; A A Ariyo; D T Price; JoAnn E Manson; J A Hill
Factor V Leiden mutation as a risk factor for recurrent pregnancy loss.
Annals of internal medicine 1998;128(12 Pt 1):1000-3.
1998: Paul M Ridker; Robert J Glynn; Charles H Hennekens
C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction.
Circulation 1998;97(20):2007-11.
1998: Paul M Ridker; M Cushman; Meir J Stampfer; R P Tracy; Charles H Hennekens
Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease.
Circulation 1998;97(5):425-8.
1998: Paul M Ridker; Charles H Hennekens; B Roitman-Johnson; Meir J Stampfer; J Allen
Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men.
Lancet 1998;351(9096):88-92.
1998: Paul M Ridker
Long-term, low-dose warfarin among venous thrombosis patients with and without factor V Leiden mutation: rationale and design for the Prevention of Recurrent Venous Thromboembolism (PREVENT) trial.
Vascular medicine (London, England) 1998;3(1):67-73.
1997: D T Price; Paul M Ridker
Factor V Leiden mutation and the risks for thromboembolic disease: a clinical perspective.
Annals of internal medicine 1997;127(10):895-903.
1997: M V McConnell; I Vavouranakis; L L Wu; D E Vaughan; Paul M Ridker
Effects of a single, daily alcoholic beverage on lipid and hemostatic markers of cardiovascular risk.
The American journal of cardiology 1997;80(9):1226-8.
1997: Paul M Ridker; M T Baker; Charles H Hennekens; Meir J Stampfer; D E Vaughan
Alu-repeat polymorphism in the gene coding for tissue-type plasminogen activator (t-PA) and risks of myocardial infarction among middle-aged men.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(9):1687-90.
1997: Douglas E Vaughan; Jean-Lucien Rouleau; Paul M Ridker; J Malcolm O Arnold; Francis Menapace; Marc A Pfeffer
Effects of ramipril on plasma fibrinolytic balance in patients with acute anterior myocardial infarction. HEART Study Investigators.
Circulation 1997;96(2):442-7.
1997: Claudia U Chae; Paul M Ridker; JoAnn E Manson
Postmenopausal hormone replacement therapy and cardiovascular disease.
Thrombosis and haemostasis 1997;78(1):770-80.
1997: Paul M Ridker
Fibrinolytic and inflammatory markers for arterial occlusion: the evolving epidemiology of thrombosis and hemostasis.
Thrombosis and haemostasis 1997;78(1):53-9.
1997: Marc A Pfeffer; Sally Greaves; J Malcolm O Arnold; Robert J Glynn; F S LaMotte; Richard T Lee; Francis Menapace; E Rapaport; Paul M Ridker; Jean-Lucien Rouleau; Scott D Solomon; Charles H Hennekens
Early versus delayed angiotensin-converting enzyme inhibition therapy in acute myocardial infarction. The healing and early afterload reducing therapy trial.
Circulation 1997;95(12):2643-51.
1997: Paul M Ridker; JP Miletich; Charles H Hennekens; Julie E Buring
Ethnic distribution of factor V Leiden in 4047 men and women. Implications for venous thromboembolism screening.
JAMA : the journal of the American Medical Association 1997;277(16):1305-7.
1997: Paul M Ridker; M Cushman; Meir J Stampfer; R P Tracy; Charles H Hennekens
Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men.
The New England journal of medicine 1997;336(14):973-9.
1997: Paul M Ridker; Charles H Hennekens; Jacob Selhub; JP Miletich; M R Malinow; Meir J Stampfer
Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism.
Circulation 1997;95(7):1777-82.
1997: Paul M Ridker; Robert J Glynn; J P Miletich; Samuel Z Goldhaber; Meir J Stampfer; Charles H Hennekens
Age-specific incidence rates of venous thromboembolism among heterozygous carriers of factor V Leiden mutation.
Annals of internal medicine 1997;126(7):528-31.
1997: C J O'Donnell; Paul M Ridker; Robert J Glynn; Klaus Berger; Umed Ajani; JoAnn E Manson; Charles H Hennekens
Hypertension and borderline isolated systolic hypertension increase risks of cardiovascular disease and mortality in male physicians.
Circulation 1997;95(5):1132-7.
1997: Paul M Ridker; Charles H Hennekens; C Schmitz; Meir J Stampfer; Klaus Lindpaintner
PIA1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis.
Lancet 1997;349(9049):385-8.
1997: Paul M Ridker; Charles H Hennekens; Klaus Lindpaintner; Meir J Stampfer; J P Miletich
Arterial and venous thrombosis is not associated with the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of US men.
Circulation 1997;95(1):59-62.
1996: William G Stevenson; Paul M Ridker
Should survivors of myocardial infarction with low ejection fraction be routinely referred to arrhythmia specialists?
JAMA : the journal of the American Medical Association 1996;276(6):481-5.
1996: Charles H Hennekens; Julie E Buring; JoAnn E Manson; Meir J Stampfer; B Rosner; Nancy R Cook; C Belanger; F LaMotte; J Michael Gaziano; Paul M Ridker; Walter C Willett; R Peto
Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease.
The New England journal of medicine 1996;334(18):1145-9.
1995: Paul M Ridker; J P Miletich; Meir J Stampfer; Samuel Z Goldhaber; Klaus Lindpaintner; Charles H Hennekens
Factor V Leiden and risks of recurrent idiopathic venous thromboembolism.
Circulation 1995;92(10):2800-2.
1995: Charles H Hennekens; C J O'Donnell; Paul M Ridker
Current and future perspectives on antithrombotic therapy of acute myocardial infarction.
European heart journal 1995;16 Suppl D():2-9.
1995: JoAnn E Manson; J Michael Gaziano; A Spelsberg; Paul M Ridker; Nancy R Cook; Julie E Buring; Walter C Willett; Charles H Hennekens
A secondary prevention trial of antioxidant vitamins and cardiovascular disease in women. Rationale, design, and methods. The WACS Research Group.
Annals of epidemiology 1995;5(4):261-9.
1995: C J O'Donnell; Paul M Ridker; P R Hebert; Charles H Hennekens
Antithrombotic therapy for acute myocardial infarction.
Journal of the American College of Cardiology 1995;25(7 Suppl):23S-29S.
1995: Charles H Hennekens; C J O'Donnell; Paul M Ridker; V J Marder
Current issues concerning thrombolytic therapy for acute myocardial infarction.
Journal of the American College of Cardiology 1995;25(7 Suppl):18S-22S.
1995: J Michael Gaziano; Elizabeth Johnson; Robert M Russell; JoAnn E Manson; Meir J Stampfer; Paul M Ridker; B Frei; Charles H Hennekens; Norman I Krinsky
Discrimination in absorption or transport of beta-carotene isomers after oral supplementation with either all-trans- or 9-cis-beta-carotene.
The American journal of clinical nutrition 1995;61(6):1248-52.
1995: Paul M Ridker; Meir J Stampfer; Charles H Hennekens
Plasma concentration of lipoprotein(a) and the risk of future stroke.
JAMA : the journal of the American Medical Association 1995;273(16):1269-73.
1995: Paul M Ridker; Charles H Hennekens; Klaus Lindpaintner; Meir J Stampfer; P R Eisenberg; J P Miletich
Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men.
The New England journal of medicine 1995;332(14):912-7.
1995: J Michael Gaziano; A Hatta; M Flynn; Elizabeth Johnson; Norman I Krinsky; Paul M Ridker; Charles H Hennekens; B Frei
Supplementation with beta-carotene in vivo and in vitro does not inhibit low density lipoprotein oxidation.
Atherosclerosis 1995;112(2):187-95.
1994: Paul M Ridker; Charles H Hennekens; A Cerskus; Meir J Stampfer
Plasma concentration of cross-linked fibrin degradation product (D-dimer) and the risk of future myocardial infarction among apparently healthy men.
Circulation 1994;90(5):2236-40.
1994: Paul M Ridker; D E Vaughan; Meir J Stampfer; Robert J Glynn; Charles H Hennekens
Association of moderate alcohol consumption and plasma concentration of endogenous tissue-type plasminogen activator.
JAMA : the journal of the American Medical Association 1994;272(12):929-33.
1994: Paul M Ridker; Charles H Hennekens
Lipoprotein(a) and risks of cardiovascular disease.
Annals of epidemiology 1994;4(5):360-2.
1994: Paul M Ridker; Charles H Hennekens; Meir J Stampfer; JoAnn E Manson; D E Vaughan
Prospective study of endogenous tissue plasminogen activator and risk of stroke.
Lancet 1994;343(8903):940-3.
1993: Scott D Solomon; Paul M Ridker; Elliott M Antman
Ventricular arrhythmias in trials of thrombolytic therapy for acute myocardial infarction. A meta-analysis.
Circulation 1993;88(6):2575-81.
1993: Paul M Ridker; Charles H Hennekens; Meir J Stampfer
A prospective study of lipoprotein(a) and the risk of myocardial infarction.
JAMA : the journal of the American Medical Association 1993;270(18):2195-9.
1993: P R Hebert; Janet W Rich-Edwards; JoAnn E Manson; Paul M Ridker; Nancy R Cook; G T O'Connor; Julie E Buring; Charles H Hennekens
Height and incidence of cardiovascular disease in male physicians.
Circulation 1993;88(4 Pt 1):1437-43.
1993: Scott D Solomon; S Wolff; H Watkins; Paul M Ridker; PC Come; W J McKenna; Christine E Seidman; Richard T Lee
Left ventricular hypertrophy and morphology in familial hypertrophic cardiomyopathy associated with mutations of the beta-myosin heavy chain gene.
Journal of the American College of Cardiology 1993;22(2):498-505.
1993: Paul M Ridker; P R Hebert; V Fuster; Charles H Hennekens
Are both aspirin and heparin justified as adjuncts to thrombolytic therapy for acute myocardial infarction?
Lancet 1993;341(8860):1574-7.
1993: Paul M Ridker; C L Gaboury; Paul R Conlin; Ellen W Seely; G H Williams; D E Vaughan
Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function.
Circulation 1993;87(6):1969-73.
1993: Paul M Ridker; D E Vaughan; Meir J Stampfer; JoAnn E Manson; Charles H Hennekens
Endogenous tissue-type plasminogen activator and risk of myocardial infarction.
Lancet 1993;341(8854):1165-8.
1992: Paul M Ridker; JoAnn E Manson; Samuel Z Goldhaber; Charles H Hennekens; Julie E Buring
Comparison of delay times to hospital presentation for physicians and nonphysicians with acute myocardial infarction.
The American journal of cardiology 1992;70(1):10-3.
1992: JoAnn E Manson; H Tosteson; Paul M Ridker; S Satterfield; P Hebert; G T O'Connor; Julie E Buring; Charles H Hennekens
The primary prevention of myocardial infarction.
The New England journal of medicine 1992;326(21):1406-16.
1992: Paul M Ridker; D E Vaughan; Meir J Stampfer; JoAnn E Manson; C Shen; L M Newcomer; Samuel Z Goldhaber; Charles H Hennekens
Baseline fibrinolytic state and the risk of future venous thrombosis. A prospective study of endogenous tissue-type plasminogen activator and plasminogen activator inhibitor.
Circulation 1992;85(5):1822-7.
1991: Paul M Ridker; JoAnn E Manson; J E Buring; Samuel Z Goldhaber; Charles H Hennekens
Clinical characteristics of nonfatal myocardial infarction among individuals on prophylactic low-dose aspirin therapy.
Circulation 1991;84(2):708-11.
1991: Paul M Ridker; JoAnn E Manson; J Michael Gaziano; Julie E Buring; Charles H Hennekens
Low-dose aspirin therapy for chronic stable angina. A randomized, placebo-controlled clinical trial.
Annals of internal medicine 1991;114(10):835-9.
1990: Paul M Ridker; JoAnn E Manson; Julie E Buring; J E Muller; Charles H Hennekens
Circadian variation of acute myocardial infarction and the effect of low-dose aspirin in a randomized trial of physicians.
Circulation 1990;82(3):897-902.
1989: Paul M Ridker; W V McDermott
Comfrey herb tea and hepatic veno-occlusive disease.
Lancet 1989;1(8639):657-8.