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Anne Ridley

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Co-Publications
Name
8
Jones, Gareth
8
Riento, Kirsi
6
Leverrier, Yann
5
Wells, Claire
5
Allen, William
5
Garg, Ritu
4
Vanhaesebroeck, Bart
4
Guasch, Rosa
4
Ivetic, Aleksandar
3
Tybulewicz, Victor
3
Wheeler, Ann
3
Wójciak-Stothard, B
3
Millán, Jaime
3
Franz, Clemens
3
Cory, Giles

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Publications

TOP 3
Bright Michael D; Garner Andrew P; Ridley Anne J
PAK1 and PAK2 have different roles in HGF-induced morphological responses.
Bhavsar Parag J; Vigorito Elena; Turner Martin; Ridley Anne J
Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation.
Cain Robert J; Ridley Anne J
Phosphoinositide 3-kinases in cell migration.

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All Publications

2009: Bright Michael D; Garner Andrew P; Ridley Anne J
PAK1 and PAK2 have different roles in HGF-induced morphological responses.
Cellular signalling 2009;21(12):1738-47.
2009: Bhavsar Parag J; Vigorito Elena; Turner Martin; Ridley Anne J
Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation.
Experimental cell research 2009;315(19):3345-58.
2009: Cain Robert J; Ridley Anne J
Phosphoinositide 3-kinases in cell migration.
Biology of the cell / under the auspices of the European Cell Biology Organization 2009;101(1):13-29.
2008: Papakonstanti Evangelia A; Zwaenepoel Olivier; Bilancio Antonio; Burns Emily; Nock Gemma E; Houseman Benjamin; Shokat Kevan; Ridley Anne J; Vanhaesebroeck Bart
Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages.
Journal of cell science 2008;121(Pt 24):4124-33.
2008: Smith Stephen D; Jaffer Zahara M; Chernoff Jonathan; Ridley Anne J
PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics.
Journal of cell science 2008;121(Pt 22):3729-36.
2008: Ridley A J
Regulation of macrophage adhesion and migration by Rho GTP-binding proteins.
Journal of microscopy 2008;231(3):518-23.
2008: Heasman Sarah J; Ridley Anne J
Mammalian Rho GTPases: new insights into their functions from in vivo studies.
Nature reviews. Molecular cell biology 2008;9(9):690-701.
2008: Vega Francisco M; Ridley Anne J
Rho GTPases in cancer cell biology.
FEBS letters 2008;582(14):2093-101.
2008: Garg Ritu; Riento Kirsi; Keep Nicholas; Morris Jonathan D H; Ridley Anne J
N-terminus-mediated dimerization of ROCK-I is required for RhoE binding and actin reorganization.
The Biochemical journal 2008;411(2):407-14.
2008: Valderrama Ferran; Ridley Anne J
Getting invasive with GEP100 and Arf6.
Nature cell biology 2008;10(1):16-8.
2007: Wheeler Ann P; Ridley Anne J
RhoB affects macrophage adhesion, integrin expression and migration.
Experimental cell research 2007;313(16):3505-16.
2007: McKenzie Jenny A G; Ridley Anne J
Roles of Rho/ROCK and MLCK in TNF-alpha-induced changes in endothelial morphology and permeability.
Journal of cellular physiology 2007;213(1):221-8.
2007: Papakonstanti Evangelia A; Ridley Anne J; Vanhaesebroeck Bart
The p110delta isoform of PI 3-kinase negatively controls RhoA and PTEN.
The EMBO journal 2007;26(13):3050-61.
2007: Vega Francisco M; Ridley Anne J
SnapShot: Rho family GTPases.
Cell 2007;129(7):1430.
2006: Ridley Anne J
Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking.
Trends in cell biology 2006;16(10):522-9.
2006: Villalonga Priam; Ridley Anne J
Rho GTPases and cell cycle control.
Growth factors (Chur, Switzerland) 2006;24(3):159-64.
2006: Katso Roy M; Pardo Olivier E; Palamidessi Andrea; Franz Clemens M; Marinov Marin; De Laurentiis Angela; Downward Julian; Scita Giorgio; Ridley Anne J; Waterfield Michael D; Arcaro Alexandre
Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.
Molecular biology of the cell 2006;17(9):3729-44.
2006: Erwig Lars-Peter; McPhilips Kathleen A; Wynes Murray W; Ivetic Alexander; Ridley Anne J; Henson Peter M
Differential regulation of phagosome maturation in macrophages and dendritic cells mediated by Rho GTPases and ezrin-radixin-moesin (ERM) proteins.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(34):12825-30.
2006: Swetman Andersen Claire A; Handley Matthew; Pollara Gabriel; Ridley Anne J; Katz David R; Chain Benjamin M
beta1-Integrins determine the dendritic morphology which enhances DC-SIGN-mediated particle capture by dendritic cells.
International immunology 2006;18(8):1295-303.
2006: Wheeler Ann P; Wells Claire M; Smith Stephen D; Vega Francisco M; Henderson Robert B; Tybulewicz Victor L; Ridley Anne J
Rac1 and Rac2 regulate macrophage morphology but are not essential for migration.
Journal of cell science 2006;119(Pt 13):2749-57.
2006: McKenzie Jenny A G; Riento Kirsi; Ridley Anne J
Casein kinase I epsilon associates with and phosphorylates the tight junction protein occludin.
FEBS letters 2006;580(9):2388-94.
2006: Cernuda-Morollón Eva; Ridley Anne J
Rho GTPases and leukocyte adhesion receptor expression and function in endothelial cells.
Circulation research 2006;98(6):757-67.
2006: Wheeler Ann P; Smith Stephen D; Ridley Anne J
CSF-1 and PI 3-kinase regulate podosome distribution and assembly in macrophages.
Cell motility and the cytoskeleton 2006;63(3):132-40.
2006: Millán Jaime; Hewlett Lindsay; Glyn Matthew; Toomre Derek; Clark Peter; Ridley Anne J
Lymphocyte transcellular migration occurs through recruitment of endothelial ICAM-1 to caveola- and F-actin-rich domains.
Nature cell biology 2006;8(2):113-23.
2006: Garg Ritu; Ridley Anne J
Mammalian cell microinjection assay to study the function of Rho family guanosine triphosphatases.
Methods in molecular biology (Clifton, N.J.) 2006;332():257-67.
2006: Millán Jaime; Williams Lynn; Ridley Anne J
An in vitro model to study the role of endothelial rho GTPases during leukocyte transendothelial migration.
Methods in enzymology 2006;406():643-55.
2006: Riento Kirsi; Ridley Anne J
Inhibition of ROCK by RhoE.
Methods in enzymology 2006;406():533-41.
2005: Wells Claire M; Bhavsar Parag J; Evans Iwan R; Vigorito Elena; Turner Martin; Tybulewicz Victor; Ridley Anne J
Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization.
Experimental cell research 2005;310(2):303-10.
2005: Huang Miao-Tzu; Mason Justin C; Birdsey Graeme M; Amsellem Valerie; Gerwin Nicole; Haskard Dorian O; Ridley Anne J; Randi Anna M
Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis.
Blood 2005;106(5):1636-43.
2005: Riento Kirsi; Totty Nick; Villalonga Priam; Garg Ritu; Guasch Rosa; Ridley Anne J
RhoE function is regulated by ROCK I-mediated phosphorylation.
The EMBO journal 2005;24(6):1170-80.
2005: Millán Jaime; Ridley Anne J
Rho GTPases and leucocyte-induced endothelial remodelling.
The Biochemical journal 2005;385(Pt 2):329-37.
2005: Wells Claire M; Ridley Anne J
Analysis of cell migration using the Dunn chemotaxis chamber and time-lapse microscopy.
Methods in molecular biology (Clifton, N.J.) 2005;294():31-41.
2004: Ivetic A; Ridley A J
The telling tail of L-selectin.
Biochemical Society transactions 2004;32(Pt 6):1118-21.
2004: Wheeler Ann P; Ridley Anne J
Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility.
Experimental cell research 2004;301(1):43-9.
2004: Villalonga Priam; Guasch Rosa M; Riento Kirsi; Ridley Anne J
RhoE inhibits cell cycle progression and Ras-induced transformation.
Molecular and cellular biology 2004;24(18):7829-40.
2004: Ivetic Aleksandar; Florey Oliver; Deka Jürgen; Haskard Dorian O; Ager Ann; Ridley Anne J
Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering.
The Journal of biological chemistry 2004;279(32):33263-72.
2004: Ivetic Aleksandar; Ridley Anne J
Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes.
Immunology 2004;112(2):165-76.
2004: Ridley Anne J
Rho proteins and cancer.
Breast cancer research and treatment 2004;84(1):13-9.
2004: Wells Claire M; Walmsley Marita; Ooi Steen; Tybulewicz Victor; Ridley Anne J
Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration.
Journal of cell science 2004;117(Pt 7):1259-68.
2004: Ridley Anne J
Pulling back to move forward.
Cell 2004;116(3):357-8.
2004: Franz Clemens M; Ridley Anne J
p120 catenin associates with microtubules: inverse relationship between microtubule binding and Rho GTPase regulation.
The Journal of biological chemistry 2004;279(8):6588-94.
2004: Ridley Anne J; Hall Alan
Snails, Swiss, and serum: the solution for Rac 'n' Rho.
Cell 2004;116(2 Suppl):S23-5, 2 p following S25.
2003: Ridley Anne J; Schwartz Martin A; Burridge Keith; Firtel Richard A; Ginsberg Mark H; Borisy Gary; Parsons J Thomas; Horwitz Alan Rick
Cell migration: integrating signals from front to back.
Science (New York, N.Y.) 2003;302(5651):1704-9.
2003: Bird Margaret M; Lopez-Lluch Guillermo; Ridley Anne J; Segal A W
Effects of microinjected small GTPases on the actin cytoskeleton of human neutrophils.
Journal of anatomy 2003;203(4):379-89.
2003: Jones Gareth E; Prigmore Elena; Calvez Ronan; Hogan Catherine; Dunn Graham A; Hirsch Emilio; Wymann Matthias P; Ridley Anne J
Requirement for PI 3-kinase gamma in macrophage migration to MCP-1 and CSF-1.
Experimental cell research 2003;290(1):120-31.
2003: Mataraza Jennifer M; Briggs Michael W; Li Zhigang; Entwistle Alan; Ridley Anne J; Sacks David B
IQGAP1 promotes cell motility and invasion.
The Journal of biological chemistry 2003;278(42):41237-45.
2003: Leverrier Yann; Okkenhaug Klaus; Sawyer Carol; Bilancio Antonio; Vanhaesebroeck Bart; Ridley Anne J
Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages.
The Journal of biological chemistry 2003;278(40):38437-42.
2003: Riento Kirsi; Ridley Anne J
Rocks: multifunctional kinases in cell behaviour.
Nature reviews. Molecular cell biology 2003;4(6):446-56.
2003: Riento Kirsi; Guasch Rosa M; Garg Ritu; Jin Boquan; Ridley Anne J
RhoE binds to ROCK I and inhibits downstream signaling.
Molecular and cellular biology 2003;23(12):4219-29.
2003: Cory Giles O C; Cramer Rainer; Blanchoin Laurent; Ridley Anne J
Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP.
Molecular cell 2003;11(5):1229-39.
2003: Wojciak-Stothard Beata; Ridley Anne J
Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases.
The Journal of cell biology 2003;161(2):429-39.
2002: Wojciak-Stothard Beata; Ridley Anne J
Rho GTPases and the regulation of endothelial permeability.
Vascular pharmacology 2002;39(4-5):187-99.
2002: Cory Giles O C; Garg Ritu; Cramer Rainer; Ridley Anne J
Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein.
The Journal of biological chemistry 2002;277(47):45115-21.
2002: Wells Claire M; Abo Arie; Ridley Anne J
PAK4 is activated via PI3K in HGF-stimulated epithelial cells.
Journal of cell science 2002;115(Pt 20):3947-56.
2002: Cory Giles O C; Ridley Anne J
Cell motility: braking WAVEs.
Nature 2002;418(6899):732-3.
2002: Swetman Claire A; Leverrier Yann; Garg Ritu; Gan Chih H V; Ridley Anne J; Katz David R; Chain Benjamin M
Extension, retraction and contraction in the formation of a dendritic cell dendrite: distinct roles for Rho GTPases.
European journal of immunology 2002;32(7):2074-83.
2002: Thompson Paul W; Randi Anna M; Ridley Anne J
Intercellular adhesion molecule (ICAM)-1, but not ICAM-2, activates RhoA and stimulates c-fos and rhoA transcription in endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(2):1007-13.
2002: Garavini Halina; Riento Kirsi; Phelan John P; McAlister Mark S B; Ridley Anne J; Keep Nicholas H
Crystal structure of the core domain of RhoE/Rnd3: a constitutively activated small G protein.
Biochemistry 2002;41(20):6303-10.
2002: Franz Clemens M; Jones Gareth E; Ridley Anne J
Cell migration in development and disease.
Developmental cell 2002;2(2):153-8.
2001: Ridley A J
Rho family proteins: coordinating cell responses.
Trends in cell biology 2001;11(12):471-7.
2001: Hoffmann P R; deCathelineau A M; Ogden C A; Leverrier Y; Bratton D L; Daleke D L; Ridley A J; Fadok V A; Henson P M
Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells.
The Journal of cell biology 2001;155(4):649-59.
2001: Ridley A J
Cyclin' round the cell with Rac.
Developmental cell 2001;1(2):160-1.
2001: Ridley A J
Rho GTPases and cell migration.
Journal of cell science 2001;114(Pt 15):2713-22.
2001: Ridley A J
Rho proteins, PI 3-kinases, and monocyte/macrophage motility.
FEBS letters 2001;498(2-3):168-71.
2001: Ridley A J
Rho proteins: linking signaling with membrane trafficking.
Traffic (Copenhagen, Denmark) 2001;2(5):303-10.
2001: Leverrier Y; Lorenzi R; Blundell M P; Brickell P; Kinnon C; Ridley A J; Thrasher A J
Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(8):4831-4.
2001: Leverrier Y; Ridley A J
Apoptosis: caspases orchestrate the ROCK 'n' bleb.
Nature cell biology 2001;3(4):E91-3.
2001: Wójciak-Stothard B; Potempa S; Eichholtz T; Ridley A J
Rho and Rac but not Cdc42 regulate endothelial cell permeability.
Journal of cell science 2001;114(Pt 7):1343-55.
2001: Leverrier Y; Ridley A J
Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages.
Current biology : CB 2001;11(3):195-9.
2000: Williams L M; Ridley A J
Lipopolysaccharide induces actin reorganization and tyrosine phosphorylation of Pyk2 and paxillin in monocytes and macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):2028-36.
2000: Jones G E; Ridley A J; Zicha D
Rho GTPases and cell migration: measurement of macrophage chemotaxis.
Methods in enzymology 2000;325():449-62.
1999: Wójciak-Stothard B; Williams L; Ridley A J
Monocyte adhesion and spreading on human endothelial cells is dependent on Rho-regulated receptor clustering.
The Journal of cell biology 1999;145(6):1293-307.
1999: Vanhaesebroeck B; Jones G E; Allen W E; Zicha D; Hooshmand-Rad R; Sawyer C; Wells C; Waterfield M D; Ridley A J
Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages.
Nature cell biology 1999;1(1):69-71.
1999: Peppelenbosch M; Boone E; Jones G E; van Deventer S J; Haegeman G; Fiers W; Grooten J; Ridley A J
Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: inhibition of Cdc42-mediated filopodium formation by TNF.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):837-45.
1999: Ridley A J; Allen W E; Peppelenbosch M; Jones G E
Rho family proteins and cell migration.
Biochemical Society symposium 1999;65():111-23.
1999: Ridley A J
Rho family proteins and regulation of the actin cytoskeleton.
Progress in molecular and subcellular biology 1999;22():1-22.
1998: Potempa S; Ridley A J
Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly.
Molecular biology of the cell 1998;9(8):2185-200.
1998: Guasch R M; Scambler P; Jones G E; Ridley A J
RhoE regulates actin cytoskeleton organization and cell migration.
Molecular and cellular biology 1998;18(8):4761-71.
1998: Wójciak-Stothard B; Entwistle A; Garg R; Ridley A J
Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells.
Journal of cellular physiology 1998;176(1):150-65.
1998: Allen W E; Zicha D; Ridley A J; Jones G E
A role for Cdc42 in macrophage chemotaxis.
The Journal of cell biology 1998;141(5):1147-57.
1998: Jones G E; Allen W E; Ridley A J
The Rho GTPases in macrophage motility and chemotaxis.
Cell adhesion and communication 1998;6(2-3):237-45.
1998: Ridley A J
Mammalian cell microinjection assay to study the function of Rac and Rho.
Methods in molecular biology (Clifton, N.J.) 1998;84():153-60.
1997: Ridley A J
The GTP-binding protein Rho.
The international journal of biochemistry & cell biology 1997;29(11):1225-9.
1997: Ridley A J
Signalling by Rho family proteins.
Biochemical Society transactions 1997;25(3):1005-10.
1997: Allen W E; Jones G E; Pollard J W; Ridley A J
Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages.
Journal of cell science 1997;110 ( Pt 6)():707-20.
1996: Norman J C; Price L S; Ridley A J; Koffer A
The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways.
Molecular biology of the cell 1996;7(9):1429-42.
1996: Flinn H M; Ridley A J
Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin.
Journal of cell science 1996;109 ( Pt 5)():1133-41.
1995: Ridley A J
Intracellular regulation. Rac and Bcr regulate phagocytic phoxes.
Current biology : CB 1995;5(7):710-2.
1995: Price L S; Norman J C; Ridley A J; Koffer A
The small GTPases Rac and Rho as regulators of secretion in mast cells.
Current biology : CB 1995;5(1):68-73.
1995: Ridley A J
Microinjection of Rho and Rac into quiescent Swiss 3T3 cells.
Methods in enzymology 1995;256():313-20.
1995: Ridley A J
Growth factor-induced actin reorganization in Swiss 3T3 cells.
Methods in enzymology 1995;256():306-13.
1994: Norman J C; Price L S; Ridley A J; Hall A; Koffer A
Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins.
The Journal of cell biology 1994;126(4):1005-15.
1994: Ridley A J
Membrane ruffling and signal transduction.
BioEssays : news and reviews in molecular, cellular and developmental biology 1994;16(5):321-7.
1994: Ridley A J
Signal transduction through the GTP-binding proteins Rac and Rho.
Journal of cell science. Supplement 1994;18():127-31.

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