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Caterina Bianco

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Caterina Bianco; David S Salomon
Targeting the embryonic gene Cripto-1 in cancer and beyond.
Caterina Bianco; Maria Cristina Rangel; Nadia P Castro; Tadahiro Nagaoka; Kelly Rollman; Monica Gonzales; David S Salomon
Role of Cripto-1 in stem cell maintenance and malignant progression.
Kazuhide Watanabe; Matthew J Meyer; Luigi Strizzi; Joseph M Lee; Monica Gonzales; Caterina Bianco; Tadahiro Nagaoka; Shahram S Farid; Naira Margaryan; Mary J C Hendrix; Barbara K Vonderhaar; David S Salomon
Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells.

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All Publications

2010: Caterina Bianco; David S Salomon
Targeting the embryonic gene Cripto-1 in cancer and beyond.
Expert opinion on therapeutic patents 2010;20(12):1739-49.
2010: Caterina Bianco; Maria Cristina Rangel; Nadia P Castro; Tadahiro Nagaoka; Kelly Rollman; Monica Gonzales; David S Salomon
Role of Cripto-1 in stem cell maintenance and malignant progression.
The American journal of pathology 2010;177(2):532-40.
2010: Kazuhide Watanabe; Matthew J Meyer; Luigi Strizzi; Joseph M Lee; Monica Gonzales; Caterina Bianco; Tadahiro Nagaoka; Shahram S Farid; Naira Margaryan; Mary J C Hendrix; Barbara K Vonderhaar; David S Salomon
Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells.
Stem cells (Dayton, Ohio) 2010;28(8):1303-14.
2010: Nadia Pereira de Castro; Maria Cristina Rangel; Tadahiro Nagaoka; David S Salomon; Caterina Bianco
Cripto-1: an embryonic gene that promotes tumorigenesis.
Future oncology (London, England) 2010;6(7):1127-42.
2009: Kazuhide Watanabe; Tadahiro Nagaoka; Joseph M Lee; Caterina Bianco; Monica Gonzales; Nadia P Castro; Maria Cristina Rangel; Kei Sakamoto; Youping Sun; Robert Callahan; David S Salomon
Enhancement of Notch receptor maturation and signaling sensitivity by Cripto-1.
The Journal of cell biology 2009;187(3):343-53.
2009: Caterina Bianco; Catherine Cotten; Enza Lonardo; Luigi Strizzi; Christina Baraty; Mario Mancino; Monica Gonzales; Kazuhide Watanabe; Tadahiro Nagaoka; Colin Berry; Andrew Arai; Gabriella Minchiotti; David S Salomon
Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells.
The American journal of pathology 2009;175(5):2146-58.
2009: Mario Mancino; Claudia Esposito; Kazuhide Watanabe; Tadahiro Nagaoka; Monica Gonzales; Caterina Bianco; Nicola Normanno; David S Salomon; Luigi Strizzi
Neuronal guidance protein Netrin-1 induces differentiation in human embryonal carcinoma cells.
Cancer research 2009;69(5):1717-21.
2008: Caterina Bianco; Margaret Mysliwiec; Kazuhide Watanabe; Mario Mancino; Tadahiro Nagaoka; Monica Gonzales; David S Salomon
Activation of a Nodal-independent signaling pathway by Cripto-1 mutants with impaired activation of a Nodal-dependent signaling pathway.
FEBS letters 2008;582(29):3997-4002.
2008: Kazuhide Watanabe; Tadahiro Nagaoka; Luigi Strizzi; Mario Mancino; Monica Gonzales; Caterina Bianco; David S Salomon
Characterization of the glycosylphosphatidylinositol-anchor signal sequence of human Cryptic with a hydrophilic extension.
Biochimica et biophysica acta 2008;1778(12):2671-81.
2008: Morihisa Hirota; Kazuhide Watanabe; Shin Hamada; Youping Sun; Luigi Strizzi; Mario Mancino; Tadahiro Nagaoka; Monica Gonzales; Masaharu Seno; Caterina Bianco; David S Salomon
Smad2 functions as a co-activator of canonical Wnt/beta-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of p300.
Cellular signalling 2008;20(9):1632-41.
2008: Luigi Strizzi; Mario Mancino; Caterina Bianco; Ahmed Raafat; Monica Gonzales; Brian W Booth; Kazuhide Watanabe; Tadahiro Nagaoka; David L Mack; Beatrice Howard; Robert Callahan; Gilbert H Smith; David S Salomon
Netrin-1 can affect morphogenesis and differentiation of the mouse mammary gland.
Journal of cellular physiology 2008;216(3):824-34.
2008: Mario Mancino; Luigi Strizzi; Christian Wechselberger; Kazuhide Watanabe; Monica Gonzales; Shin Hamada; Nicola Normanno; David S Salomon; Caterina Bianco
Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells.
Journal of cellular physiology 2008;215(1):192-203.
2008: Caterina Bianco; Luigi Strizzi; Mario Mancino; Kazuhide Watanabe; Monica Gonzales; Shin Hamada; Ahmed Raafat; Lawson Sahlah; Cindy Chang; Federica Sotgia; Nicola Normanno; Michael Lisanti; David S Salomon
Regulation of Cripto-1 signaling and biological activity by caveolin-1 in mammary epithelial cells.
The American journal of pathology 2008;172(2):345-57.
2007: Kazuhide Watanabe; Shin Hamada; Caterina Bianco; Mario Mancino; Tadahiro Nagaoka; Monica Gonzales; Veronique Bailly; Luigi Strizzi; David S Salomon
Requirement of glycosylphosphatidylinositol anchor of Cripto-1 for trans activity as a Nodal co-receptor.
The Journal of biological chemistry 2007;282(49):35772-86.
2007: Kazuhide Watanabe; Caterina Bianco; Luigi Strizzi; Shin Hamada; Mario Mancino; Veronique Bailly; Wenjun Mo; Dingyi Wen; Konrad Miatkowski; Monica Gonzales; Michele Sanicola; Masaharu Seno; David S Salomon
Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
The Journal of biological chemistry 2007;282(43):31643-55.
2007: Shin Hamada; Kazuhide Watanabe; Morihisa Hirota; Caterina Bianco; Luigi Strizzi; Mario Mancino; Monica Gonzales; David S Salomon
beta-Catenin/TCF/LEF regulate expression of the short form human Cripto-1.
Biochemical and biophysical research communications 2007;355(1):240-4.
2007: Luigi Strizzi; Caterina Bianco; Morihisa Hirota; Kazuhide Watanabe; Mario Mancino; Shin Hamada; Ahmed Raafat; S Lawson; Andreas Ebert; Antonio D'Antonio; Simona Losito; Nicola Normanno; David S Salomon
Development of leiomyosarcoma of the uterus in MMTV-CR-1 transgenic mice.
The Journal of pathology 2007;211(1):36-44.
2006: Caterina Bianco; Luigi Strizzi; Mario Mancino; Aasia Rehman; Shin Hamada; Kazuhide Watanabe; Antonella De Luca; Brenda Jones; Gabriela A Balogh; Jose Russo; Daniel Mailo; Raffaele Palaia; Giuseppe D'Aiuto; Gerardo Botti; Francesco Perrone; David S Salomon; Nicola Normanno
Identification of cripto-1 as a novel serologic marker for breast and colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(17):5158-64.
2006: Nicola Normanno; Antonella De Luca; Caterina Bianco; Luigi Strizzi; Mario Mancino; Monica R Maiello; Adele Carotenuto; Gianfranco De Feo; Francesco Caponigro; David S Salomon
Epidermal growth factor receptor (EGFR) signaling in cancer.
Gene 2006;366(1):2-16.
2005: Christian Wechselberger; Caterina Bianco; Luigi Strizzi; Andreas Ebert; Nicholas Kenney; Youping Sun; David S Salomon
Modulation of TGF-beta signaling by EGF-CFC proteins.
Experimental cell research 2005;310(2):249-55.
2005: Luigi Strizzi; Caterina Bianco; Ahmed Raafat; Wissam Abdallah; Cindy Chang; Dina Raafat; Morihisa Hirota; Shin Hamada; Youping Sun; Nicola Normanno; Robert Callahan; Lindsay Hinck; David Salomon
Netrin-1 regulates invasion and migration of mouse mammary epithelial cells overexpressing Cripto-1 in vitro and in vivo.
Journal of cell science 2005;118(Pt 20):4633-43.
2005: Luigi Strizzi; Caterina Bianco; Nicola Normanno; David Salomon
Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis.
Oncogene 2005;24(37):5731-41.
2005: Youping Sun; William Lowther; Katsuaki Kato; Caterina Bianco; Nicholas Kenney; Luigi Strizzi; Dina Raafat; Morihisa Hirota; Nadia I Khan; Sharon Bargo; Brenda Jones; David Salomon; Robert Callahan
Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling.
Oncogene 2005;24(34):5365-74.
2005: Youping Sun; Luigi Strizzi; Ahmed Raafat; Morihisa Hirota; Caterina Bianco; Lionel Feigenbaum; Nicholas Kenney; Christian Wechselberger; Robert Callahan; David S Salomon
Overexpression of human Cripto-1 in transgenic mice delays mammary gland development and differentiation and induces mammary tumorigenesis.
The American journal of pathology 2005;167(2):585-97.
2005: Christian Wechselberger; Luigi Strizzi; Nicholas Kenney; Morihisa Hirota; Youping Sun; Andreas Ebert; Olivia Orozco; Caterina Bianco; Nadia I Khan; Brenda Wallace-Jones; Nicola Normanno; Heather B Adkins; Michele Sanicola; David S Salomon
Human Cripto-1 overexpression in the mouse mammary gland results in the development of hyperplasia and adenocarcinoma.
Oncogene 2005;24(25):4094-105.
2005: Nicola Normanno; Caterina Bianco; Luigi Strizzi; Mario Mancino; Monica R Maiello; Antonella De Luca; Francesco Caponigro; David S Salomon
The ErbB receptors and their ligands in cancer: an overview.
Current drug targets 2005;6(3):243-57.
2005: Caterina Bianco; Luigi Strizzi; Andreas Ebert; Cindy Chang; Aasia Rehman; Nicola Normanno; Liliana Guedez; Rita Salloum; Erika Ginsburg; Youping Sun; Nadia Khan; Morihisa Hirota; Brenda Wallace-Jones; Christian Wechselberger; Barbara K Vonderhaar; Giovanna Tosato; William Stetler-Stevenson; Michele Sanicola; David S Salomon
Role of human cripto-1 in tumor angiogenesis.
Journal of the National Cancer Institute 2005;97(2):132-41.
2005: Caterina Bianco; Luigi Strizzi; Nicola Normanno; Nadia Khan; David S Salomon
Cripto-1: an oncofetal gene with many faces.
Current topics in developmental biology 2005;67():85-133.
2004: Luigi Strizzi; Caterina Bianco; Nicola Normanno; Masaharu Seno; Christian Wechselberger; Brenda Wallace-Jones; Nadia I Khan; Morihisa Hirota; Youping Sun; Michele Sanicola; David S Salomon
Epithelial mesenchymal transition is a characteristic of hyperplasias and tumors in mammary gland from MMTV-Cripto-1 transgenic mice.
Journal of cellular physiology 2004;201(2):266-76.
2004: Nicola Normanno; Antonella De Luca; Monica R Maiello; Caterina Bianco; Mario Mancino; Luigi Strizzi; Claudio Arra; Fortunato Ciardiello; Sudhir Agrawal; David S Salomon
CRIPTO-1: a novel target for therapeutic intervention in human carcinoma.
International journal of oncology 2004;25(4):1013-20.
2004: Caterina Bianco; Nicola Normanno; David S Salomon; Fortunato Ciardiello
Role of the cripto (EGF-CFC) family in embryogenesis and cancer.
Growth factors (Chur, Switzerland) 2004;22(3):133-9.
2004: Nicola Normanno; Antonella De Luca; Caterina Bianco; Monica R Maiello; Maria Vincenza Carriero; Aasia Rehman; Christian Wechselberger; Claudio Arra; Luigi Strizzi; Michele Sanicola; David S Salomon
Cripto-1 overexpression leads to enhanced invasiveness and resistance to anoikis in human MCF-7 breast cancer cells.
Journal of cellular physiology 2004;198(1):31-9.
2003: Heather B Adkins; Caterina Bianco; Susan G Schiffer; Paul Rayhorn; Mohammad Zafari; Anne E Cheung; Olivia Orozco; Dian Olson; Antonella De Luca; Ling Ling Chen; Konrad Miatkowski; Christopher D Benjamin; Nicola Normanno; Kevin P Williams; Matthew Jarpe; Doreen J Lepage; David Salomon; Michele Sanicola
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo.
The Journal of clinical investigation 2003;112(4):575-87.
2003: Caterina Bianco; Luigi Strizzi; Aasia Rehman; Nicola Normanno; Christian Wechselberger; Youping Sun; Nadia Khan; Morihisa Hirota; Heather B Adkins; Kevin Williams; Richard U Margolis; Michele Sanicola; David S Salomon
A Nodal- and ALK4-independent signaling pathway activated by Cripto-1 through Glypican-1 and c-Src.
Cancer research 2003;63(6):1192-7.
2003: Nicola Normanno; Caterina Bianco; A De Luca; Monica R Maiello; David S Salomon
Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment.
Endocrine-related cancer 2003;10(1):1-21.
2002: Antonio D'Antonio; Simona Losito; Sandro Pignata; Michele Grassi; Francesco Perrone; Antonella De Luca; Rosa Tambaro; Caterina Bianco; William J Gullick; Gibbes R Johnson; Vincenzo Rosario Iaffaioli; David S Salomon; Nicola Normanno
Transforming growth factor alpha, amphiregulin and cripto-1 are frequently expressed in advanced human ovarian carcinomas.
International journal of oncology 2002;21(5):941-8.
2002: Caterina Bianco; Heather B Adkins; Christian Wechselberger; Masaharu Seno; Nicola Normanno; Antonella De Luca; Youping Sun; Nadia Khan; Nicholas Kenney; Andreas Ebert; Kevin P Williams; Michele Sanicola; David S Salomon
Cripto-1 activates nodal- and ALK4-dependent and -independent signaling pathways in mammary epithelial Cells.
Molecular and cellular biology 2002;22(8):2586-97.
2002: Caterina Bianco; Nicola Normanno; Antonella De Luca; Monica R Maiello; Christian Wechselberger; Youping Sun; Nadia Khan; Heather B Adkins; Michele Sanicola; Barbara K Vonderhaar; Bruce Cohen; Masaharu Seno; David Salomon
Detection and localization of Cripto-1 binding in mouse mammary epithelial cells and in the mouse mammary gland using an immunoglobulin-cripto-1 fusion protein.
Journal of cellular physiology 2002;190(1):74-82.
2001: Christian Wechselberger; Andreas Ebert; Caterina Bianco; Nadia I Khan; Youping Sun; Brenda Wallace-Jones; R Montesano; David S Salomon
Cripto-1 enhances migration and branching morphogenesis of mouse mammary epithelial cells.
Experimental cell research 2001;266(1):95-105.
2001: Caterina Bianco; Christian Wechselberger; Andreas Ebert; Nadia I Khan; Youping Sun; David S Salomon
Identification of Cripto-1 in human milk.
Breast cancer research and treatment 2001;66(1):1-7.
2001: I Martínez-Lacaci; ML De Santis; S Kannan; Caterina Bianco; Norma Kim; Brenda Wallace-Jones; Christian Wechselberger; Andreas Ebert; David S Salomon
Regulation of heparin-binding EGF-like growth factor expression in Ha-ras transformed human mammary epithelial cells.
Journal of cellular physiology 2001;186(2):233-42.
2000: D S Saloman; Caterina Bianco; Andreas Ebert; Nadia I Khan; ML De Santis; Nicola Normanno; Christian Wechselberger; Masaharu Seno; K Williams; Michele Sanicola; S Foley; W J Gullick; G Persico
The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.
Endocrine-related cancer 2000;7(4):199-226.
2000: I Martínez-Lacaci; S Kannan; ML De Santis; Caterina Bianco; Norma Kim; Brenda Wallace-Jones; Andreas Ebert; Christian Wechselberger; David S Salomon
RAS transformation causes sustained activation of epidermal growth factor receptor and elevation of mitogen-activated protein kinase in human mammary epithelial cells.
International journal of cancer. Journal international du cancer 2000;88(1):44-52.
2000: Andreas Ebert; Christian Wechselberger; Matthias Nees; Timothy Clair; Gerhard Schaller; I Martinez-Lacaci; Brenda Wallace-Jones; Caterina Bianco; HK Weitzel; David S Salomon
Cripto-1-induced increase in vimentin expression is associated with enhanced migration of human Caski cervical carcinoma cells.
Experimental cell research 2000;257(1):223-9.
2000: Andreas Ebert; Christian Wechselberger; I Martinez-Lacaci; Caterina Bianco; HK Weitzel; David S Salomon
Expression and function of EGF-related peptides and their receptors in gynecological cancer--from basic science to therapy.
Journal of receptor and signal transduction research 2000;20(1):1-46.
1999: Andreas Ebert; Christian Wechselberger; S Frank; Brenda Wallace-Jones; M Seno; I Martinez-Lacaci; Caterina Bianco; M De Santis; HK Weitzel; David S Salomon
Cripto-1 induces phosphatidylinositol 3'-kinase-dependent phosphorylation of AKT and glycogen synthase kinase 3beta in human cervical carcinoma cells.
Cancer research 1999;59(18):4502-5.
1999: Caterina Bianco; S Kannan; ML De Santis; Masaharu Seno; Careen K Tang; I Martinez-Lacaci; Norma Kim; Brenda Wallace-Jones; Marc Lippman; Andreas Ebert; Christian Wechselberger; David S Salomon
Cripto-1 indirectly stimulates the tyrosine phosphorylation of erb B-4 through a novel receptor.
The Journal of biological chemistry 1999;274(13):8624-9.
1999: David S Salomon; Caterina Bianco; M De Santis
Cripto: a novel epidermal growth factor (EGF)-related peptide in mammary gland development and neoplasia.
BioEssays : news and reviews in molecular, cellular and developmental biology 1999;21(1):61-70.
1997: ML De Santis; S Kannan; Gilbert H Smith; Masaharu Seno; Caterina Bianco; Norma Kim; I Martinez-Lacaci; Brenda Wallace-Jones; David S Salomon
Cripto-1 inhibits beta-casein expression in mammary epithelial cells through a p21ras-and phosphatidylinositol 3'-kinase-dependent pathway.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(12):1257-66.
1997: S Kannan; ML De Santis; M Lohmeyer; DJ Riese; Gilbert H Smith; N Hynes; Masaharu Seno; R Brandt; Caterina Bianco; G Persico; Nicholas Kenney; Nicola Normanno; I Martinez-Lacaci; F Ciardiello; David F Stern; W J Gullick; David S Salomon
Cripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cells.
The Journal of biological chemistry 1997;272(6):3330-5.
1996: Gabriella Mincione; Caterina Bianco; S Kannan; Giulia Colletta; Fortunato Ciardiello; M Sliwkowski; Y Yarden; Nicola Normanno; A Pramaggiore; N Kim; David S Salomon
Enhanced expression of heregulin in c-erb B-2 and c-Ha-ras transformed mouse and human mammary epithelial cells.
Journal of cellular biochemistry 1996;60(4):437-46.