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Ernst Th Rietschel

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Bernard Prendergast; Nicole Probst-Hensch; Ernst Th Rietschel; Hartmut Rütten; Caroline Steingen; Alain Tedgui; Wiek van Gilst; Heyo K Kroemer; Anne Lücke; Heini Murer; Eike Nagel; Ludwig Neyses; Joep Perk; Leslie T Coope; Harry Crijns; Thomas Eschenhagen; Elisabeth Falkenstein; Ulrich Fölsch; Sigrun Halvorsen; Stefan Janssens; Eero Jokinen; Steen Dalby Kristensen
The German Centre for Cardiovascular Research.
Ernst Th Rietschel
East German institutes stand tall.
I Khatri; Christian Alexander; Klaus Brandenburg; Karin Fournier; Jean-Pierre Mach; Ernst Th Rietschel; Artur J Ulmer; E Terzioglu; Th Waelli; Reginald M Gorczynski
Induction of tolerogenic vs immunogenic dendritic cells (DCs) in the presence of GM-CSF is regulated by the strength of signaling from monophosphoryl lipid A (MPLA) in association with glutathione and fetal hemoglobin gamma-chain.

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2012: Bernard Prendergast; Nicole Probst-Hensch; Ernst Th Rietschel; Hartmut Rütten; Caroline Steingen; Alain Tedgui; Wiek van Gilst; Heyo K Kroemer; Anne Lücke; Heini Murer; Eike Nagel; Ludwig Neyses; Joep Perk; Leslie T Coope; Harry Crijns; Thomas Eschenhagen; Elisabeth Falkenstein; Ulrich Fölsch; Sigrun Halvorsen; Stefan Janssens; Eero Jokinen; Steen Dalby Kristensen
The German Centre for Cardiovascular Research.
European heart journal 2012;33(9):1033-36,1036a.
2010: Ernst Th Rietschel
East German institutes stand tall.
Science (New York, N.Y.) 2010;327(5964):412.
2009: I Khatri; Christian Alexander; Klaus Brandenburg; Karin Fournier; Jean-Pierre Mach; Ernst Th Rietschel; Artur J Ulmer; E Terzioglu; Th Waelli; Reginald M Gorczynski
Induction of tolerogenic vs immunogenic dendritic cells (DCs) in the presence of GM-CSF is regulated by the strength of signaling from monophosphoryl lipid A (MPLA) in association with glutathione and fetal hemoglobin gamma-chain.
Immunology letters 2009;124(1):44-9.
2008: I Khatri; Christian Alexander; Klaus Brandenburg; Karin Fournier; Lydia Lee; Jean-Pierre Mach; Ernst Th Rietschel; Artur J Ulmer; Th Waelli; Reginald M Gorczynski
A role for altered TLR gene expression in association with increased expression of CD200R in the induction of mucosal tissue CD4(+) Treg in aged mice following gavage with a liver extract along with intramuscular monophosphoryl lipid A (MPLA) injection.
Experimental gerontology 2008;43(8):771-81.
2008: Jörg Howe; Patrick Garidel; Manfred Roessle; Walter Richter; Christian Alexander; Karin Fournier; Jean-Pierre Mach; Th Waelli; Reginald M Gorczynski; Artur J Ulmer; Ulrich Zähringer; Alfred Hartmann; Ernst Th Rietschel; Klaus Brandenburg
Structural investigations into the interaction of hemoglobin and part structures with bacterial endotoxins.
Innate immunity 2008;14(1):39-49.
2007: Reginald M Gorczynski; Christian Alexander; Wolfgang G Bessler; K Brandenburg; Karin Fournier; Jean-Pierre Mach; S Mueller; Ernst Th Rietschel; A J Ulmer; Th Waelli; U Zahringer; I Khatri
An alteration in the levels of populations of CD4+ Treg is in part responsible for altered cytokine production by cells of aged mice which follows injection with a fetal liver extract.
Immunology letters 2007;109(2):101-12.
2007: Jörg Howe; Malte Hammer; Christian Alexander; Manfred Rössle; Karin Fournier; Jean-Pierre Mach; Th Waelli; Reginald M Gorczynski; Artur J Ulmer; Ulrich Zähringer; Ernst Th Rietschel; Klaus Brandenburg
Biophysical characterization of the interaction of endotoxins with hemoglobins.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2007;3(1):13-20.
2006: Reginald M Gorczynski; Christian Alexander; Wolfgang G Bessler; K Brandenburg; Karin Fournier; Petra Hoffmann; Jean-Pierre Mach; S Mueller; Ernst Th Rietschel; E Terzioglu; A J Ulmer; Th Waelli; U Zahringer; I Khatri
Role of MIF and glutathione, in association with fetal ovine globin chain (Hbgamma) and LPS, in induction of TNFalpha from cells of young and aged mice, and PBL from healthy human populations.
Immunology letters 2006;105(2):140-9.
2006: Irina M Yermak; Viktoria N Davidova; Vladimir I Gorbach; Pavel Lukyanov; Tamara F Solov'eva; Arthur J Ulmer; Ute Buwitt-Beckmann; Ernst Th Rietschel; Yu S Ovodov
Forming and immunological properties of some lipopolysaccharide-chitosan complexes.
Biochimie 2006;88(1):23-30.
2005: Silke Müller; Petra Hoffmann; Ulrich V D Esche; Jean-Pierre Mach; Reginald M Gorczynski; Th Waelli; Christian Alexander; Ulrich Zähringer; Ernst Th Rietschel; Wolfgang G Bessler; Otto Westphal
A fetal sheep liver extract containing immunostimulatory substances including LPS acts as leukocyte activator in cells of LPS responder and non responder mice.
International immunopharmacology 2005;5(13-14):1809-19.
2005: Reginald M Gorczynski; Christian Alexander; Wolfgang G Bessler; Karin Fournier; Petra Hoffmann; Jean-Pierre Mach; Ernst Th Rietschel; L Song; Th Waelli; Otto Westphal; U Zahringer; I Khatri
Analysis of interaction of cloned human and/or sheep fetal hemoglobin gamma-chain and LPS in augmenting induction of inflammatory cytokine production in vivo and in vitro.
Immunology letters 2005;100(2):120-9.
2005: Ernst Th Rietschel
Otto H. E. Westphal (1913-2004).
Journal of endotoxin research 2005;11(1):63-4.
2004: Reginald M Gorczynski; Christian Alexander; Wolfgang G Bessler; Karin Fournier; Petra Hoffmann; Jean-Pierre Mach; J Manuel; Vankayalapati Ramakrishna; Ernst Th Rietschel; L Song; Th Waelli; Otto Westphal; U Zahringer
Characterization of an interaction between fetal hemoglobin and lipid A of LPS resulting in augmented induction of cytokine production in vivo and in vitro.
International immunopharmacology 2004;4(14):1859-72.
2004: Boris A Dmitriev; Filip V Toukach; O Holst; Ernst Th Rietschel; Stefan Ehlers
Tertiary structure of Staphylococcus aureus cell wall murein.
Journal of bacteriology 2004;186(21):7141-8.
2004: Ernst Th Rietschel; Mireille Rietschel; Bruce Beutler
How the mighty have fallen: fatal infectious diseases of divine composers.
Infectious disease clinics of North America 2004;18(2):311-39, table of contents.
2003: Ernst Th Rietschel; Jean-Marc Cavaillon
Richard Pfeiffer and Alexandre Besredka: creators of the concept of endotoxin and anti-endotoxin.
Microbes and infection / Institut Pasteur 2003;5(15):1407-14.
2003: Boris A Dmitriev; Filip V Toukach; Klaus-Jürgen Schaper; Otto Holst; Ernst Th Rietschel; Stefan Ehlers
Tertiary structure of bacterial murein: the scaffold model.
Journal of bacteriology 2003;185(11):3458-68.
2003: Bruce Beutler; Ernst Th Rietschel
Innate immune sensing and its roots: the story of endotoxin.
Nature reviews. Immunology 2003;3(2):169-76.
2002: Lubomir Grozdanov; Ulrich Zähringer; Gabriele Blum-Oehler; Lore Brade; Anke Henne; Yuriy A Knirel; Ursula Schombel; Jürgen Schulze; Ulrich Sonnenborn; Gerhard Gottschalk; Jörg Hacker; Ernst Th Rietschel; Ulrich Dobrindt
A single nucleotide exchange in the wzy gene is responsible for the semirough O6 lipopolysaccharide phenotype and serum sensitivity of Escherichia coli strain Nissle 1917.
Journal of bacteriology 2002;184(21):5912-25.
2002: Holger Janusch; Lothar Brecker; Buko Lindner; Christian Alexander; Sabine Gronow; Holger Heine; Artur J Ulmer; Ernst Th Rietschel; Ulrich Zähringer
Structural and biological characterization of highly purified hepta-acyl lipid A present in the lipopolysaccharide of the Salmonella enterica sv. Minnesota Re deep rough mutant strain R595.
Journal of endotoxin research 2002;8(5):343-56.
2002: Ernst Th Rietschel; Jean-Marc Cavaillon
Endotoxin and anti-endotoxin. The contribution of the schools of Koch and Pasteur: life, milestone-experiments and concepts of Richard Pfeiffer (Berlin) and Alexandre Besredka (Paris).
Journal of endotoxin research 2002;8(2):71-82.
2002: Ernst Th Rietschel; Jean-Marc Cavaillon
Endotoxin and anti-endotoxin. The contribution of the schools of Koch and Pasteur: life, milestone-experiments and concepts of Richard Pfeiffer (Berlin) and Alexandre Besredka (Paris).
Journal of endotoxin research 2002;8(1):3-16.
2001: C Alexander; Ernst Th Rietschel
Bacterial lipopolysaccharides and innate immunity.
Journal of endotoxin research 2001;7(3):167-202.
2001: S G Plötz; Arnd Lentschat; H Behrendt; W Plötz; Lutz Hamann; J Ring; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
The interaction of human peripheral blood eosinophils with bacterial lipopolysaccharide is CD14 dependent.
Blood 2001;97(1):235-41.
2000: Ernst Th Rietschel
[Immortal music and mortal septicemias. Fatal sepsis of famous composers].
Recenti progressi in medicina 2000;91(9):461-7.
2000: Boris A Dmitriev; Stefan Ehlers; Ernst Th Rietschel; P J Brennan
Molecular mechanics of the mycobacterial cell wall: from horizontal layers to vertical scaffolds.
International journal of medical microbiology : IJMM 2000;290(3):251-8.
2000: JM Warnecke; Martin Nitschke; C E Moolenaar; Ernst Th Rietschel; Roland K Hartmann; U Mamat
The 5'-proximal hairpin loop of lbi RNA is a key structural element in repression of D-galactan II biosynthesis in Klebsiella pneumoniae serotype O1.
Molecular microbiology 2000;36(3):697-709.
2000: Andra B Schromm; Klaus Brandenburg; Harald Loppnow; A P Moran; Michel H J Koch; Ernst Th Rietschel; Ulrich Seydel
Biological activities of lipopolysaccharides are determined by the shape of their lipid A portion.
European journal of biochemistry / FEBS 2000;267(7):2008-13.
2000: Lutz Hamann; Ralf R Schumann; Hans-Dieter Flad; Lore Brade; Ernst Th Rietschel; Artur J Ulmer
Binding of lipopolysaccharide (LPS) to CHO cells does not correlate with LPS-induced NF-kappaB activation.
European journal of immunology 2000;30(1):211-6.
1999: Stefan Ehlers; S Kutsch; J Benini; A Cooper; C Hahn; Johannes Gerdes; I Orme; C Martin; Ernst Th Rietschel
NOS2-derived nitric oxide regulates the size, quantity and quality of granuloma formation in Mycobacterium avium-infected mice without affecting bacterial loads.
Immunology 1999;98(3):313-23.
1999: Stefan Ehlers; J Benini; S Kutsch; R Endres; Ernst Th Rietschel; Klaus Pfeffer
Fatal granuloma necrosis without exacerbated mycobacterial growth in tumor necrosis factor receptor p55 gene-deficient mice intravenously infected with Mycobacterium avium.
Infection and immunity 1999;67(7):3571-9.
1999: Arnd Lentschat; Volker El-Samalouti; J Schletter; Shoichi Kusumoto; Lore Brade; Ernst Th Rietschel; J Gerdes; Martin Ernst; Hans-Dieter Flad; Artur J Ulmer
The internalization time course of a given lipopolysaccharide chemotype does not correspond to its activation kinetics in monocytes.
Infection and immunity 1999;67(5):2515-21.
1999: Patricia Sánchez Carballo; Ernst Th Rietschel; kosma paul; Ulrich Zähringer
Elucidation of the structure of an alanine-lacking core tetrasaccharide trisphosphate from the lipopolysaccharide of Pseudomonas aeruginosa mutant H4.
European journal of biochemistry / FEBS 1999;261(2):500-8.
1999: Boris A Dmitriev; Stefan Ehlers; Ernst Th Rietschel
Layered murein revisited: a fundamentally new concept of bacterial cell wall structure, biogenesis and function.
Medical microbiology and immunology 1999;187(3):173-81.
1999: A Woltmann; Sophie C Gangloff; Hans-Peter Bruch; Ernst Th Rietschel; Werner Solbach; Jack Silver; Sanna Goyert
Reduced bacterial dissemination and liver injury in CD14-deficient mice following a chronic abscess-forming peritonitis induced by Bacteroides fragilis.
Medical microbiology and immunology 1999;187(3):149-56.
1999: T Mattern; G Girroleit; Hans-Dieter Flad; Ernst Th Rietschel; Artur J Ulmer
CD34(+) hematopoietic stem cells exert accessory function in lipopolysaccharide-induced T cell stimulation and CD80 expression on monocytes.
The Journal of experimental medicine 1999;189(4):693-700.
1998: Andra B Schromm; Klaus Brandenburg; Harald Loppnow; Ulrich Zähringer; Ernst Th Rietschel; SF Carroll; Michel H J Koch; Shoichi Kusumoto; Ulrich Seydel
The charge of endotoxin molecules influences their conformation and IL-6-inducing capacity.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(10):5464-71.
1998: Lutz Hamann; Volker El-Samalouti; Artur J Ulmer; Hans-Dieter Flad; Ernst Th Rietschel
Components of gut bacteria as immunomodulators.
International journal of food microbiology 1998;41(2):141-54.
1998: T Mattern; Hans-Dieter Flad; Lore Brade; Ernst Th Rietschel; Artur J Ulmer
Stimulation of human T lymphocytes by LPS is MHC unrestricted, but strongly dependent on B7 interactions.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3412-8.
1998: A Woltmann; Lutz Hamann; Artur J Ulmer; J Gerdes; Hans-Peter Bruch; Ernst Th Rietschel
Molecular mechanisms of sepsis.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 1998;383(1):2-10.
1998: A Woltmann; Ernst Th Rietschel; Hans-Peter Bruch
[Is a 3-month USA sojourn of value for a German university surgeon?].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115():845-6.
1998: Ernst Th Rietschel; J Schletter; B Weidemann; Volker El-Samalouti; T Mattern; Ulrich Zähringer; Ulrich Seydel; Helmut Brade; Hans-Dieter Flad; Shoichi Kusumoto; D Gupta; Roman Dziarski; Artur J Ulmer
Lipopolysaccharide and peptidoglycan: CD14-dependent bacterial inducers of inflammation.
Microbial drug resistance (Larchmont, N.Y.) 1998;4(1):37-44.
1998: Harald Loppnow; R Bil; S Hirt; Uwe Schönbeck; Mona Herzberg; Karl Werdan; Ernst Th Rietschel; Ernst Brandt; Hans-Dieter Flad
Platelet-derived interleukin-1 induces cytokine production, but not proliferation of human vascular smooth muscle cells.
Blood 1998;91(1):134-41.
1997: Volker El-Samalouti; J Schletter; Helmut Brade; Lore Brade; Shoichi Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Detection of lipopolysaccharide (LPS)-binding membrane proteins by immuno-coprecipitation with LPS and anti-LPS antibodies.
European journal of biochemistry / FEBS 1997;250(2):418-24.
1997: Ulrich Zähringer; Frauke Wagner; Ernst Th Rietschel; G Ben-Menachem; J Deutsch; Shlomo Rottem
Primary structure of a new phosphocholine-containing glycoglycerolipid of Mycoplasma fermentans.
The Journal of biological chemistry 1997;272(42):26262-70.
1997: G Ben-Menachem; Frauke Wagner; Ulrich Zähringer; Ernst Th Rietschel; Shlomo Rottem
Antibody response to MfGL-II, a phosphocholine-containing major lipid of Mycoplasma fermentans membranes.
FEMS microbiology letters 1997;154(2):363-9.
1997: Lore Brade; R Engel; W J Christ; Ernst Th Rietschel
A nonsubstituted primary hydroxyl group in position 6' of free lipid A is required for binding of lipid A monoclonal antibodies.
Infection and immunity 1997;65(9):3961-5.
1997: Andre Wiese; Klaus Brandenburg; SF Carroll; Ernst Th Rietschel; Ulrich Seydel
Mechanisms of action of bactericidal/permeability-increasing protein BPI on reconstituted outer membranes of gram-negative bacteria.
Biochemistry 1997;36(33):10311-9.
1997: Andre Wiese; Klaus Brandenburg; Buko Lindner; Andra B Schromm; SF Carroll; Ernst Th Rietschel; Ulrich Seydel
Mechanisms of action of the bactericidal/permeability-increasing protein BPI on endotoxin and phospholipid monolayers and aggregates.
Biochemistry 1997;36(33):10301-10.
1997: B Weidemann; J Schletter; Roman Dziarski; Shoichi Kusumoto; Felix Stelter; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes.
Infection and immunity 1997;65(3):858-64.
1996: Andra B Schromm; Klaus Brandenburg; Ernst Th Rietschel; Hans-Dieter Flad; SF Carroll; Ulrich Seydel
Lipopolysaccharide-binding protein mediates CD14-independent intercalation of lipopolysaccharide into phospholipid membranes.
FEBS letters 1996;399(3):267-71.
1996: Otto Holst; Artur J Ulmer; Helmut Brade; Hans-Dieter Flad; Ernst Th Rietschel
Biochemistry and cell biology of bacterial endotoxins.
FEMS immunology and medical microbiology 1996;16(2):83-104.
1996: Ernst Th Rietschel; Helmut Brade; Otto Holst; Lore Brade; Sven Müller-Loennies; Uwe Mamat; Ulrich Zähringer; F Beckmann; Ulrich Seydel; Klaus Brandenburg; Artur J Ulmer; T Mattern; Holger Heine; J Schletter; Harald Loppnow; Uwe Schönbeck; Hans-Dieter Flad; Sunna Hauschildt; U F Schade; F Di Padova; S Kusumoto; Ralf R Schumann
Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification.
Current topics in microbiology and immunology 1996;216():39-81.
1995: J Schletter; Holger Heine; Artur J Ulmer; Ernst Th Rietschel
Molecular mechanisms of endotoxin activity.
Archives of microbiology 1995;164(6):383-9.
1995: C Krziwon; Ulrich Zähringer; K Kawahara; B Weidemann; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Glycosphingolipids from Sphingomonas paucimobilis induce monokine production in human mononuclear cells.
Infection and immunity 1995;63(8):2899-905.
1995: J Schletter; Helmut Brade; Lore Brade; C Krüger; Harald Loppnow; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Binding of lipopolysaccharide (LPS) to an 80-kilodalton membrane protein of human cells is mediated by soluble CD14 and LPS-binding protein.
Infection and immunity 1995;63(7):2576-80.
1995: Yasuo Suda; Teruo Kirikae; T Shiyama; T Yasukochi; Fumiko Kirikae; M Nakano; Ernst Th Rietschel; S Kusumoto
Macrophage activation in response to S-form lipopolysaccharides (LPS) separated by centrifugal partition chromatography from wild-type LPS: effects of the O-polysaccharide portion of LPS.
Biochemical and biophysical research communications 1995;210(3):678-85.
1995: Uwe Mamat; Ernst Th Rietschel; G Schmidt
Repression of lipopolysaccharide biosynthesis in Escherichia coli by an antisense RNA of Acetobacter methanolicus phage Acm1.
Molecular microbiology 1995;15(6):1115-25.
1995: Ulrich Zähringer; Y A Knirel; B Lindner; J H Helbig; A Sonesson; R Marre; Ernst Th Rietschel
The lipopolysaccharide of Legionella pneumophila serogroup 1 (strain Philadelphia 1): chemical structure and biological significance.
Progress in clinical and biological research 1995;392():113-39.
1994: B Weidemann; Helmut Brade; Ernst Th Rietschel; Roman Dziarski; V Bazil; S Kusumoto; Hans-Dieter Flad; Artur J Ulmer
Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures.
Infection and immunity 1994;62(11):4709-15.
1994: T Mattern; A Thanhäuser; N Reiling; Kai-Michael Toellner; Michael Duchrow; S Kusumoto; Ernst Th Rietschel; Martin Ernst; Helmut Brade; Hans-Dieter Flad
Endotoxin and lipid A stimulate proliferation of human T cells in the presence of autologous monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(7):2996-3004.
1994: Teruo Kirikae; F U Schade; Fumiko Kirikae; N Qureshi; K Takayama; Ernst Th Rietschel
Diphosphoryl lipid A derived from the lipopolysaccharide (LPS) of Rhodobacter sphaeroides ATCC 17023 is a potent competitive LPS inhibitor in murine macrophage-like J774.1 cells.
FEMS immunology and medical microbiology 1994;9(3):237-43.
1994: H D Grimmecke; Y A Knirel; Bärbel Kiesel; M Voges; Ernst Th Rietschel
Structure of the Acetobacter methanolicus MB 129 capsular polysaccharide, and of oligosaccharides resulting from degradation by bacteriophage Acm7.
Carbohydrate research 1994;259(1):45-58.
1994: Y A Knirel; Ernst Th Rietschel; R Marre; Ulrich Zähringer
The structure of the O-specific chain of Legionella pneumophila serogroup 1 lipopolysaccharide.
European journal of biochemistry / FEBS 1994;221(1):239-45.
1994: Ernst Th Rietschel; Teruo Kirikae; F U Schade; Uwe Mamat; G Schmidt; Harald Loppnow; Artur J Ulmer; Ulrich Zähringer; Ulrich Seydel; F Di Padova
Bacterial endotoxin: molecular relationships of structure to activity and function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(2):217-25.
1994: Teruo Kirikae; F U Schade; Ulrich Zähringer; Fumiko Kirikae; Helmut Brade; S Kusumoto; T Kusama; Ernst Th Rietschel
The significance of the hydrophilic backbone and the hydrophobic fatty acid regions of lipid A for macrophage binding and cytokine induction.
FEMS immunology and medical microbiology 1994;8(1):13-26.
1994: Ulrich Zähringer; Buko Lindner; Ernst Th Rietschel
Molecular structure of lipid A, the endotoxic center of bacterial lipopolysaccharides.
Advances in carbohydrate chemistry and biochemistry 1994;50():211-76.
1994: Ulrich Seydel; Klaus Brandenburg; Ernst Th Rietschel
A case for an endotoxic conformation.
Progress in clinical and biological research 1994;388():17-30.
1993: Klaus Brandenburg; H Mayer; Michel H J Koch; J Weckesser; Ernst Th Rietschel; Ulrich Seydel
Influence of the supramolecular structure of free lipid A on its biological activity.
European journal of biochemistry / FEBS 1993;218(2):555-63.
1993: H M Kuhn; Lore Brade; Ben J Appelmelk; S Kusumoto; Ernst Th Rietschel; Helmut Brade
The antibody reactivity of monoclonal lipid A antibodies is influenced by the acylation pattern of lipid A and the assay system employed.
Immunobiology 1993;189(5):457-71.
1993: Teruo Kirikae; F U Schade; Fumiko Kirikae; Ernst Th Rietschel; David C Morrison
Isolation of a macrophage-like cell line defective in binding of lipopolysaccharide. Influence of serum and lipopolysaccharide chain length on macrophage activation.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(5):2742-52.
1993: Ernst Th Rietschel; Lore Brade; F U Schade; Ulrich Seydel; Ulrich Zähringer; Uwe Mamat; G Schmidt; Artur J Ulmer; Harald Loppnow; Hans-Dieter Flad
[Bacterial endotoxins: relationship between chemical structure and biological effect].
Immunität und Infektion 1993;21(2):26-35.
1993: Hans-Dieter Flad; Harald Loppnow; Ernst Th Rietschel; Artur J Ulmer
Agonists and antagonists for lipopolysaccharide-induced cytokines.
Immunobiology 1993;187(3-5):303-16.
1993: Ernst Th Rietschel; Teruo Kirikae; F U Schade; Artur J Ulmer; Otto Holst; Helmut Brade; G Schmidt; Uwe Mamat; H D Grimmecke; S Kusumoto
The chemical structure of bacterial endotoxin in relation to bioactivity.
Immunobiology 1993;187(3-5):169-90.
1992: Artur J Ulmer; W Feist; Holger Heine; Teruo Kirikae; Fumiko Kirikae; S Kusumoto; T Kusama; Helmut Brade; U Schade; Ernst Th Rietschel
Modulation of endotoxin-induced monokine release in human monocytes by lipid A partial structures that inhibit binding of 125I-lipopolysaccharide.
Infection and immunity 1992;60(12):5145-52.
1992: Artur J Ulmer; Holger Heine; W Feist; S Kusumoto; T Kusama; Helmut Brade; U Schade; Ernst Th Rietschel; Hans-Dieter Flad
Biological activity of synthetic phosphonooxyethyl analogs of lipid A and lipid A partial structures.
Infection and immunity 1992;60(8):3309-14.
1992: H M Kuhn; Lore Brade; Ben J Appelmelk; S Kusumoto; Ernst Th Rietschel; Helmut Brade
Characterization of the epitope specificity of murine monoclonal antibodies directed against lipid A.
Infection and immunity 1992;60(6):2201-10.
1992: V A Kulshin; Ulrich Zähringer; B Lindner; C E Frasch; C M Tsai; B A Dmitriev; Ernst Th Rietschel
Structural characterization of the lipid A component of pathogenic Neisseria meningitidis.
Journal of bacteriology 1992;174(6):1793-800.
1991: M H Wang; Hans-Dieter Flad; W Feist; Helmut Brade; S Kusumoto; Ernst Th Rietschel; Artur J Ulmer
Inhibition of endotoxin-induced interleukin-6 production by synthetic lipid A partial structures in human peripheral blood mononuclear cells.
Infection and immunity 1991;59(12):4655-64.
1991: Ernst Th Rietschel; Ulrich Seydel; Ulrich Zähringer; U F Schade; Lore Brade; Harald Loppnow; W Feist; M H Wang; Artur J Ulmer; Hans-Dieter Flad
Bacterial endotoxin: molecular relationships between structure and activity.
Infectious disease clinics of North America 1991;5(4):753-79.
1991: Teruo Kirikae; Fumiko Kirikae; F U Schade; M Yoshida; S Kondo; Kazuhito Hisatsune; S Nishikawa; Ernst Th Rietschel
Detection of lipopolysaccharide-binding proteins on membranes of murine lymphocyte and macrophage-like cell lines.
FEMS microbiology immunology 1991;3(6):327-36.
1991: S Kondo; Ulrich Zähringer; Ulrich Seydel; V Sinnwell; Kazuhito Hisatsune; Ernst Th Rietschel
Chemical structure of the carbohydrate backbone of Vibrio parahaemolyticus serotype 012 lipopolysaccharide.
European journal of biochemistry / FEBS 1991;200(3):689-98.
1991: V A Kulshin; Ulrich Zähringer; B Lindner; K E Jäger; B A Dmitriev; Ernst Th Rietschel
Structural characterization of the lipid A component of Pseudomonas aeruginosa wild-type and rough mutant lipopolysaccharides.
European journal of biochemistry / FEBS 1991;198(3):697-704.
1991: A P Moran; Ulrich Zähringer; Ulrich Seydel; D Scholz; P Stütz; Ernst Th Rietschel
Structural analysis of the lipid A component of Campylobacter jejuni CCUG 10936 (serotype O:2) lipopolysaccharide. Description of a lipid A containing a hybrid backbone of 2-amino-2-deoxy-D-glucose and 2,3-diamino-2,3-dideoxy-D-glucose.
European journal of biochemistry / FEBS 1991;198(2):459-69.
1991: Hans-Dieter Flad; W Feist; M H Wang; Helmut Brade; Ernst Th Rietschel; Artur J Ulmer
Induction and modulation of interleukin 1 production by defined partial structures of lipopolysaccharide.
Behring Institute Mitteilungen 1991;(88):112-9.
1991: A P Moran; Ernst Th Rietschel; T U Kosunen; Ulrich Zähringer
Chemical characterization of Campylobacter jejuni lipopolysaccharides containing N-acetylneuraminic acid and 2,3-diamino-2,3-dideoxy-D-glucose.
Journal of bacteriology 1991;173(2):618-26.
1990: M H Wang; W Feist; H Herzbeck; Helmut Brade; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Suppressive effect of lipid A partial structures on lipopolysaccharide or lipid A-induced release of interleukin 1 by human monocytes.
FEMS microbiology immunology 1990;2(3):179-85.
1990: A A Lindberg; A Weintraub; U Zähringer; Ernst Th Rietschel
Structure-activity relationships in lipopolysaccharides of Bacteroides fragilis.
Reviews of infectious diseases 1990;12 Suppl 2():S133-41.
1990: Harald Loppnow; I Dürrbaum; Helmut Brade; C A Dinarello; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad
Lipid A, the immunostimulatory principle of lipopolysaccharides?
Advances in experimental medicine and biology 1990;256():561-6.
1990: K Tanamoto; U Shade; Ernst Th Rietschel; S Kusumuto; T Shiba
Endotoxic induction of prostaglandin release from macrophages by nontoxic lipid A analogs synthesized chemically.
Infection and immunity 1990;58(1):217-21.
1990: Ernst Th Rietschel; Lore Brade; U Schade; Ulrich Seydel; Ulrich Zähringer; Klaus Brandenburg; I Helander; Otto Holst; S Kondo; H M Kuhn
Bacterial lipopolysaccharides: relationship of structure and conformation to endotoxic activity, serological specificity and biological function.
Advances in experimental medicine and biology 1990;256():81-99.
1989: Ulrich Seydel; Klaus Brandenburg; M H Koch; Ernst Th Rietschel
Supramolecular structure of lipopolysaccharide and free lipid A under physiological conditions as determined by synchrotron small-angle X-ray diffraction.
European journal of biochemistry / FEBS 1989;186(1-2):325-32.
1989: K Tanamoto; U Schade; Ernst Th Rietschel
Sensitization of alveolar macrophages to lipopolysaccharide-induced prostaglandin synthesis by exogenous prostaglandins.
Biochemical and biophysical research communications 1989;165(1):526-32.
1989: A Weintraub; U Zähringer; H W Wollenweber; Ulrich Seydel; Ernst Th Rietschel
Structural characterization of the lipid A component of Bacteroides fragilis strain NCTC 9343 lipopolysaccharide.
European journal of biochemistry / FEBS 1989;183(2):425-31.
1989: Harald Loppnow; Helmut Brade; I Dürrbaum; C A Dinarello; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad
IL-1 induction-capacity of defined lipopolysaccharide partial structures.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3229-38.
1989: T Lüderitz; Klaus Brandenburg; Ulrich Seydel; A Roth; C Galanos; Ernst Th Rietschel
Structural and physicochemical requirements of endotoxins for the activation of arachidonic acid metabolism in mouse peritoneal macrophages in vitro.
European journal of biochemistry / FEBS 1989;179(1):11-6.
1989: Hans-Dieter Flad; Harald Loppnow; W Feist; M H Wang; Helmut Brade; S Kusumoto; Ernst Th Rietschel; Artur J Ulmer
Interleukin 1 and tumor necrosis factor: studies on the induction by lipopolysaccharide partial structures.
Lymphokine research 1989;8(3):235-8.
1988: I M Helander; B Lindner; Helmut Brade; K Altmann; A A Lindberg; Ernst Th Rietschel; Ulrich Zähringer
Chemical structure of the lipopolysaccharide of Haemophilus influenzae strain I-69 Rd-/b+. Description of a novel deep-rough chemotype.
European journal of biochemistry / FEBS 1988;177(3):483-92.
1988: Wieslaw Kaca; J de Jongh-Leuvenink; Ulrich Zähringer; Ernst Th Rietschel; Helmut Brade; J Verhoef; V Sinnwell
Isolation and chemical analysis of 7-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-L-glycero-D-manno-heptose as a constituent of the lipopolysaccharides of the UDP-galactose epimerase-less mutant J-5 of Escherichia coli and Vibrio cholerae.
Carbohydrate research 1988;179():289-99.
1988: Helmut Brade; Lore Brade; Ernst Th Rietschel
Structure-activity relationships of bacterial lipopolysaccharides (endotoxins). Current and future aspects.
Zentralblatt für Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology 1988;268(2):151-79.
1988: Helmut Brade; Lore Brade; U Schade; Ulrich Zähringer; Otto Holst; H M Kuhn; Antoni Rozalski; E Röhrscheidt; Ernst Th Rietschel
Structure, endotoxicity, immunogenicity and antigenicity of bacterial lipopolysaccharides (endotoxins, O-antigens).
Progress in clinical and biological research 1988;272():17-45.
1987: Ernst Th Rietschel; Lore Brade; U Schade; C Galanos; Marina A Freudenberg; O Lüderitz; S Kusumoto; T Shiba
Endotoxic properties of synthetic pentaacyl lipid A precursor Ib and a structural isomer.
European journal of biochemistry / FEBS 1987;169(1):27-31.
1987: Lore Brade; Klaus Brandenburg; H M Kuhn; S Kusumoto; I Macher; Ernst Th Rietschel; Helmut Brade
The immunogenicity and antigenicity of lipid A are influenced by its physicochemical state and environment.
Infection and immunity 1987;55(11):2636-44.
1987: Zygmunt Sidorczyk; Wieslaw Kaca; Helmut Brade; Ernst Th Rietschel; V Sinnwell; Ulrich Zähringer
Isolation and structural characterization of an 8-O-(4-amino-4-deoxy-beta-L-arabinopyranosyl)-3-deoxy-D-manno- octulosonic acid disaccharide in the lipopolysaccharide of a Proteus mirabilis deep rough mutant.
European journal of biochemistry / FEBS 1987;168(2):269-73.
1987: Ernst Th Rietschel; Lore Brade; Klaus Brandenburg; H D Flad; J de Jong-Leuveninck; K Kawahara; Buko Lindner; Harald Loppnow; T Lüderitz; U Schade
Chemical structure and biologic activity of bacterial and synthetic lipid A.
Reviews of infectious diseases 1987;9 Suppl 5():S527-36.
1987: Ernst Th Rietschel; Helmut Brade; Lore Brade; Klaus Brandenburg; U Schade; Ulrich Seydel; U Zähringer; C Galanos; O Lüderitz; O Westphal
Lipid A, the endotoxic center of bacterial lipopolysaccharides: relation of chemical structure to biological activity.
Progress in clinical and biological research 1987;231():25-53.
1986: C Galanos; O Lüderitz; Marina A Freudenberg; Lore Brade; U Schade; Ernst Th Rietschel; S Kusumoto; T Shiba
Biological activity of synthetic heptaacyl lipid A representing a component of Salmonella minnesota R595 lipid A.
European journal of biochemistry / FEBS 1986;160(1):55-9.
1986: T Lüderitz; U Schade; Ernst Th Rietschel
Formation and metabolism of leukotriene C4 in macrophages exposed to bacterial lipopolysaccharide.
European journal of biochemistry / FEBS 1986;155(2):377-82.
1985: C Galanos; O Lüderitz; Ernst Th Rietschel; O Westphal; Helmut Brade; Lore Brade; Marina A Freudenberg; U Schade; M Imoto; H Yoshimura
Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities.
European journal of biochemistry / FEBS 1985;148(1):1-5.
1985: Ernst Th Rietschel; Helmut Brade; Lore Brade; W Kaca; K Kawahara; Buko Lindner; T Lüderitz; T Tomita; U Schade; Ulrich Seydel
Newer aspects of the chemical structure and biological activity of bacterial endotoxins.
Progress in clinical and biological research 1985;189():31-51.
1984: Ulrich Seydel; B Lindner; H W Wollenweber; Ernst Th Rietschel
Structural studies on the lipid A component of enterobacterial lipopolysaccharides by laser desorption mass spectrometry. Location of acyl groups at the lipid A backbone.
European journal of biochemistry / FEBS 1984;145(3):505-9.
1984: H W Wollenweber; Ulrich Seydel; B Lindner; O Lüderitz; Ernst Th Rietschel
Nature and location of amide-bound (R)-3-acyloxyacyl groups in lipid A of lipopolysaccharides from various gram-negative bacteria.
European journal of biochemistry / FEBS 1984;145(2):265-72.
1984: Ernst Th Rietschel; H W Wollenweber; R Russa; H Brade; U Zähringer
Concepts of the chemical structure of lipid A.
Reviews of infectious diseases 1984;6(4):432-8.
1984: O Lüderitz; K Tanamoto; C Galanos; G R McKenzie; Helmut Brade; U Zähringer; Ernst Th Rietschel; S Kusumoto; T Shiba
Lipopolysaccharides: structural principles and biologic activities.
Reviews of infectious diseases 1984;6(4):428-31.
1984: K Tanamoto; U Zähringer; G R McKenzie; C Galanos; Ernst Th Rietschel; O Lüderitz; S Kusumoto; T Shiba
Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate.
Infection and immunity 1984;44(2):421-6.
1984: C Galanos; V Lehmann; O Lüderitz; Ernst Th Rietschel; O Westphal; Helmut Brade; Lore Brade; Marina A Freudenberg; T Hansen-Hagge; T Lüderitz
Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A.
European journal of biochemistry / FEBS 1984;140(2):221-7.
1984: Ernst Th Rietschel; U Zähringer; H W Wollenweber; G Miragliotta; J Musehold; T Lüderitz; U Schade
Bacterial endotoxins: chemical structure and biologic activity.
The American journal of emergency medicine 1984;2(1):60-9.
1983: H W Wollenweber; S Schlecht; O Lüderitz; Ernst Th Rietschel
Fatty acid in lipopolysaccharides of Salmonella species grown at low temperature. Identification and position.
European journal of biochemistry / FEBS 1983;130(1):167-71.
1982: Ernst Th Rietschel; H W Wollenweber; U Zähringer; O Lüderitz
Lipid A, the lipid component of bacterial lipopolysaccharides: relation of chemical structure to biological activity.
Klinische Wochenschrift 1982;60(14):705-9.
1982: H W Wollenweber; K W Broady; O Lüderitz; Ernst Th Rietschel
The chemical structure of lipid A. Demonstration of amide-linked 3-acyloxyacyl residues in Salmonella minnesota Re lipopolysaccharide.
European journal of biochemistry / FEBS 1982;124(1):191-8.
1982: Ernst Th Rietschel; U Schade; M Jensen; H W Wollenweber; O Lüderitz; S G Greisman
Bacterial endotoxins: chemical structure, biological activity and role in septicaemia.
Scandinavian journal of infectious diseases. Supplementum 1982;31():8-21.
1981: O Westphal; O Lüderitz; Ernst Th Rietschel; C Galanos
Bacterial lipopolysaccharide and its lipid A component: some historical and some current aspects.
Biochemical Society transactions 1981;9(3):191-5.
1981: K W Broady; Ernst Th Rietschel; O Lüderitz
The chemical structure of the lipid A component of lipopolysaccharides from Vibrio cholerae.
European journal of biochemistry / FEBS 1981;115(3):463-8.
1980: H W Wollenweber; Ernst Th Rietschel; T Hofstad; A Weintraub; A A Lindberg
Nature, type of linkage, quantity, and absolute configuration of (3-hydroxy) fatty acids in lipopolysaccharides from Bacteroides fragilis NCTC 9343 and related strains.
Journal of bacteriology 1980;144(3):898-903.