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Gregory Riggins

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Patrick J Killela; Kenneth W Kinzler; Nils Mandahl; Roger E McLendon; Alan K Meeker; Fredrik Mertens; GEORGES NETTO; Nickolas Papadopoulos; B Ahmed Rasheed; Zachary J Reitman; Gregory J Riggins; Thomas A Rosenquist; Mark Schiffman; Ie-Ming Shih; Dan Theodorescu; Michael Torbenson; Victor E Velculescu; Bert Vogelstein; Tian-Li Wang; Nicolas Wentzensen; Laura D Wood; Nishant Agrawal; Chetan Bettegowda; Darell D Bigner; Luis Alberto Diaz; Allan H Friedman; Henry Friedman; Gary L Gallia; Beppino C Giovanella; Arthur P Grollman; Tong-Chuan He; Yiping He; Ralph Hruban; George I Jallo; Yuchen Jiao; Ming Zhang; Hai Yan
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Chetan Bettegowda; Darell Bigner; Zev A Binder; Gary L Gallia; Ralph H Hruban; George Jallo; Yuchen Jiao; Stephen Keir; Kenneth W Kinzler; Suely Marie; Roger McLendon; Ahmed Rasheed; Zachary J Reitman; Callen J Riggins; Gregory J Riggins; Fausto J Rodriguez; Vafi Salmasi; Sueli Shinjo; Bert Vogelstein; Yuxuan Wang; Laura D Wood; Hai Yan; Nishant Agrawal; Nickolas Papadopoulos
Exomic sequencing of four rare central nervous system tumor types.
Gianna M Carvalheira; Bruno H N Nozima; Gregory J Riggins; Janete M Cerutti
DDIT3, STT3A (ITM1), ARG2 and FAM129A (Niban, C1orf24) in diagnosing thyroid carcinoma: variables that may affect the performance of this antibody-based test and promise.

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2013: Patrick J Killela; Kenneth W Kinzler; Nils Mandahl; Roger E McLendon; Alan K Meeker; Fredrik Mertens; GEORGES NETTO; Nickolas Papadopoulos; B Ahmed Rasheed; Zachary J Reitman; Gregory J Riggins; Thomas A Rosenquist; Mark Schiffman; Ie-Ming Shih; Dan Theodorescu; Michael Torbenson; Victor E Velculescu; Bert Vogelstein; Tian-Li Wang; Nicolas Wentzensen; Laura D Wood; Nishant Agrawal; Chetan Bettegowda; Darell D Bigner; Luis Alberto Diaz; Allan H Friedman; Henry Friedman; Gary L Gallia; Beppino C Giovanella; Arthur P Grollman; Tong-Chuan He; Yiping He; Ralph Hruban; George I Jallo; Yuchen Jiao; Ming Zhang; Hai Yan
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(15):6021-6.
2013: Chetan Bettegowda; Darell Bigner; Zev A Binder; Gary L Gallia; Ralph H Hruban; George Jallo; Yuchen Jiao; Stephen Keir; Kenneth W Kinzler; Suely Marie; Roger McLendon; Ahmed Rasheed; Zachary J Reitman; Callen J Riggins; Gregory J Riggins; Fausto J Rodriguez; Vafi Salmasi; Sueli Shinjo; Bert Vogelstein; Yuxuan Wang; Laura D Wood; Hai Yan; Nishant Agrawal; Nickolas Papadopoulos
Exomic sequencing of four rare central nervous system tumor types.
Oncotarget 2013;4(4):572-83.
2013: Gianna M Carvalheira; Bruno H N Nozima; Gregory J Riggins; Janete M Cerutti
DDIT3, STT3A (ITM1), ARG2 and FAM129A (Niban, C1orf24) in diagnosing thyroid carcinoma: variables that may affect the performance of this antibody-based test and promise.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013;26(4):611-3.
2012: RENYUAN BAI; Charles G Eberhart; Hart G Lidov; Verena Staedtke; Gregory J Riggins
OTX2 represses myogenic and neuronal differentiation in medulloblastoma cells.
Cancer research 2012;72(22):5988-6001.
2012: Yuchen Jiao; Patrick J Killela; Kenneth W Kinzler; Eric Lipp; Giselle Lopez; Roger McLendon; Alan K Meeker; Sueli M Oba-Shinjo; Nickolas Papadopoulos; Christopher Pirozzi; Ahmed B Rasheed; Zachary J Reitman; Gregory J Riggins; Fausto J Rodriguez; Sergio Rosemberg; Bert Vogelstein; Nishant Agrawal; Chetan Bettegowda; Darell D Bigner; Peter C Burger; Roeland F de Wilde; Luis Alberto Diaz; Allan H Friedman; Henry Friedman; Yiping He; Christopher M Heaphy; Matthias Holdhoff; Suely Kazue Nagahashi Marie; Hai Yan
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.
Oncotarget 2012;3(7):709-22.
2012: Gilson Baia; Otavia L Caballero; Cynthia Cowdrey; Janelle S Y Ho; Anita Lal; Christian Mawrin; Brent A Orr; Tarik Tihan; Gregory J Riggins
Yes-associated protein 1 is activated and functions as an oncogene in meningiomas.
Molecular cancer research : MCR 2012;10(7):904-13.
2012: marie-odile parat; Gregory J Riggins
Caveolin-1, caveolae, and glioblastoma.
Neuro-oncology 2012;14(6):679-88.
2012: I-Mei Siu; Christine Tran; Qi Zhao; Zev A Binder; CHRISTINE HANN; Masaru Ishii; Brent A Orr; Gregory J Riggins; Vafi Salmasi; Gary L Gallia
Establishment and characterization of a primary human chordoma xenograft model.
Journal of neurosurgery 2012;116(4):801-9.
2012: Kittisak Sawanyawisuth; Chaisiri Wongkham; Sopit Wongkham; Gregory J Riggins; Norie Araki
Possible involvement of cyclophilin a processing in fumagillin- induced suppression of cholangiocarcinoma cell proliferation.
Asian Pacific journal of cancer prevention : APJCP 2012;13 Suppl():137-41.
2012: Kittisak Sawanyawisuth; Chaisiri Wongkham; Norie Araki; Gregory J Riggins; Qi Zhao; Sopit Wongkham
Serial Analysis of Gene Expression Reveals Promising Therapeutic Targets for Liver Fluke-associated Cholangiocarcinoma.
Asian Pacific journal of cancer prevention : APJCP 2012;13 Suppl():89-93.
2012: Avadhut Joshi; Watcharin Loilome; I-Mei Siu; Betty M. Tyler; Gary L Gallia; Gregory J Riggins
Evaluation of tyrosine kinase inhibitor combinations for glioblastoma therapy.
PloS one 2012;7(10):e44372.
2012: Alexandra Borodovsky; Meghan J Seltzer; Gregory J Riggins
Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.
Current opinion in oncology 2012;24(1):83-9.
2011: Genevieve L Weber; Gary L Gallia; Marie-Odile Parat; Zev A Binder; Gregory J Riggins
Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells.
Oncotarget 2011;2(11):833-49.
2011: Chetan Bettegowda; Darell Bigner; Daniel P Cahill; Ralph Hruban; Yuchen Jiao; Nishant Agrawal; Suely Kazue Nagahashi Marie; Roger McLendon; Sueli M Oba-Shinjo; Nickolas Papadopoulos; Gregory J Riggins; Fausto J Rodriguez; Mark Sausen; Victor E Velculescu; Bert Vogelstein; Laura D Wood; Hai Yan; Kenneth W Kinzler
Mutations in CIC and FUBP1 contribute to human oligodendroglioma.
Science (New York, N.Y.) 2011;333(6048):1453-5.
2011: RENYUAN BAI; Gary L Gallia; Colette ApRhys; Verena Staedtke; Gregory J Riggins
Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme.
Neuro-oncology 2011;13(9):974-82.
2011: Christopher M Heaphy; Sachidanand Hebbar; Ralph Hruban; Yuchen Jiao; Kenneth W Kinzler; Alison P Klein; Anirban Maitra; Suely Kazue Nagahashi Marie; Roger McLendon; Sueli M Oba-Shinjo; G Johan A Offerhaus; Nickolas Papadopoulos; B Ahmed Rasheed; Gregory J Riggins; Fausto J Rodriguez; Chanjuan Shi; Bert Vogelstein; Hai Yan; Chetan Bettegowda; Darell D Bigner; Roeland F de Wilde; Charles G Eberhart; BARISH EDIL; Yiping He; Alan K Meeker
Altered telomeres in tumors with ATRX and DAXX mutations.
Science (New York, N.Y.) 2011;333(6041):425.
2011: Watcharin Loilome; Sirinun Juntana; Nisana Namwat; Vajarabhongsa Bhudhisawasdi; Anucha Puapairoj; Banchob Sripa; Masanao Miwa; Hideyuki Saya; Gregory J Riggins; Puangrat Yongvanit
PRKAR1A is overexpressed and represents a possible therapeutic target in human cholangiocarcinoma.
International journal of cancer. Journal international du cancer 2011;129(1):34-44.
2011: RENYUAN BAI; Verena Staedtke; Gregory J Riggins
Molecular targeting of glioblastoma: Drug discovery and therapies.
Trends in molecular medicine 2011;17(6):301-12.
2011: Zev A Binder; Michael W Johnson; Avadhut Joshi; CHRISTINE HANN; Constance A Griffin; Alessandro Olivi; Gregory J Riggins; Gary L Gallia
Glioblastoma multiforme in the Muir-Torre syndrome.
Clinical neurology and neurosurgery 2011;113(5):411-5.
2011: DONALD PARSONS; Meng Li; Xiaosong Zhang; Siân Jones; Rebecca J Leary; Jimmy Cheng-Ho Lin; Simina M Boca; Hannah Carter; Josue Samayoa; Chetan Bettegowda; Gary L Gallia; George I Jallo; Zev A Binder; Yuri Nikolsky; James Hartigan; Doug R Smith; Daniela S Gerhard; Daniel W Fults; Scott VandenBerg; Mitchel S Berger; Suely Kazue Nagahashi Marie; Sueli Mieko Oba Shinjo; Carlos Clara; Peter C Phillips; Jane E Minturn; Jaclyn A Biegel; Alexander R Judkins; Adam C Resnick; Phillip B Storm; Tom Curran; Yiping He; B Ahmed Rasheed; Henry S Friedman; Stephen T Keir; Roger McLendon; Paul A Northcott; Michael D Taylor; Peter C Burger; Gregory J Riggins; Rachel Karchin; Giovanni Parmigiani; Darell D Bigner; Hai Yan; Nickolas Papadopoulos; Bert Vogelstein; Kenneth W Kinzler; Victor E Velculescu
The genetic landscape of the childhood cancer medulloblastoma.
Science (New York, N.Y.) 2011;331(6016):435-9.
2011: Kelli A McDowell; Gregory J Riggins; Gary L Gallia
Targeting the AKT pathway in glioblastoma.
Current pharmaceutical design 2011;17(23):2411-20.
2011: Yuan Qiao; Xin Huang; Sridhar Nimmagadda ; RENYUAN BAI; Verena Staedtke; Catherine A Foss; Ian Cheong; Matthias Holdhoff; Yoshinori Kato; Martin G Pomper; Gregory J Riggins; Kenneth W Kinzler; Luis Alberto Diaz; Bert Vogelstein; Shibin Zhou
A robust approach to enhance tumor-selective accumulation of nanoparticles.
Oncotarget 2011;2(1-2):59-68.
2011: Avadhut Joshi; DONALD PARSONS; Victor E Velculescu; Gregory J Riggins
Sodium ion channel mutations in glioblastoma patients correlate with shorter survival.
Molecular cancer 2011;10():17.
2011: Flavia R M Latini; Jefferson P Hemerly; Beatriz C G Freitas; Gisele Oler; Gregory J Riggins; Janete M Cerutti
ABI3 ectopic expression reduces in vitro and in vivo cell growth properties while inducing senescence.
BMC cancer 2011;11():11.
2011: Janete M Cerutti; Gisele Oler; Rosana Delcelo; Rene Gerardt; Pedro Michaluart; Sandro J de Souza; Pedro A F Galante; Peng Huang; Gregory J Riggins
PVALB, a new Hürthle adenoma diagnostic marker identified through gene expression.
The Journal of clinical endocrinology and metabolism 2011;96(1):E151-60.
2010: Meghan J Seltzer; Bryson D Bennett; Avadhut Joshi; Ping Gao; Ajit G Thomas; Dana V Ferraris; Takashi Tsukamoto; Camilo J Rojas; Barbara Slusher; Joshua D Rabinowitz; Chi Dang; Gregory J Riggins
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.
Cancer research 2010;70(22):8981-7.
2010: Alvarez Hector; Elizabeth Montgomery; Collins A Karikari; Marcia Canto; Kerry Brandt Dunbar; JEAN WANG; Georg Feldmann; Seung-Mo Hong; Michael C Haffner; Alan K Meeker; Sacha J Holland; Jiaxin Yu; Thilo J Heckrodt; Jing Zhang; Pingyu Ding; Dane Goff; Rajinder Singh; Juan Carlos Roa; Arivusudar Marimuthu; Gregory J Riggins; James R Eshleman; Barry D Nelkin; Akhilesh Pandey; Anirban Maitra
The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma.
Cancer biology & therapy 2010;10(10):1009-18.
2010: I-Mei Siu; Betty M. Tyler; James X Chen; Charles G Eberhart; Ulrich-Wilhelm Thomale; Alessandro Olivi; George I Jallo; Gregory J Riggins; Gary L Gallia
Establishment of a human glioblastoma stemlike brainstem rodent tumor model.
Journal of neurosurgery. Pediatrics 2010;6(1):92-7.
2010: RENYUAN BAI; Verena Staedtke; I-Mei Siu; Gary L Gallia; Betty M. Tyler; Gregory J Riggins
Evaluation of retinoic acid therapy for OTX2-positive medulloblastomas.
Neuro-oncology 2010;12(7):655-63.
2010: Chien-Tsun Kuan; Kenji Wakiya; James E Herndon; Eric S Lipp; Charles N Pegram; Gregory J Riggins; Ahmed Rasheed; Scott E Szafranski; Roger E McLendon; Carol J Wikstrand; Darell D Bigner
MRP3: a molecular target for human glioblastoma multiforme immunotherapy.
BMC cancer 2010;10():468.
2010: Shailaja K Rao; Jennifer Edwards; Avadhut Joshi; I-Mei Siu; Gregory J Riggins
A survey of glioblastoma genomic amplifications and deletions.
Journal of neuro-oncology 2010;96(2):169-79.
2009: Watcharin Loilome; Avadhut Joshi; Colette ApRhys; Sara Piccirillo; Angelo L Vescovi; Vescovi L Angelo; Gary L Gallia; Gregory J Riggins
Glioblastoma cell growth is suppressed by disruption of Fibroblast Growth Factor pathway signaling.
Journal of neuro-oncology 2009;94(3):359-66.
2009: Cléber P Camacho; Flavia R M Latini; Gisele Oler; Flavio C Hojaij; Rui M B Maciel; Gregory J Riggins; Janete M Cerutti
Down-regulation of NR4A1 in follicular thyroid carcinomas is restored following lithium treatment.
Clinical endocrinology 2009;70(3):475-83.
2009: Hai Yan; DONALD PARSONS; Genglin Jin; Roger McLendon; B Ahmed Rasheed; Weishi Yuan; Ivan Kos; Ines Batinic-Haberle; Siân Jones; Gregory J Riggins; Henry Friedman; Allan Friedman; David Reardon; James Herndon; Kenneth W Kinzler; Victor E Velculescu; Bert Vogelstein; Darell D Bigner
IDH1 and IDH2 mutations in gliomas.
The New England journal of medicine 2009;360(8):765-73.
2009: Gary L Gallia; Betty M. Tyler; CHRISTINE HANN; I-Mei Siu; Vincent L Giranda; Angelo L Vescovi; Henry Brem; Gregory J Riggins
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
Molecular cancer therapeutics 2009;8(2):386-93.
2009: Christopher G Duncan; Rebecca J Leary; Jimmy Cheng-Ho Lin; Jordan Cummins; Chunhui Di; Carl F Schaefer; Tian-Li Wang; Gregory J Riggins; Jennifer Edwards; Darell Bigner; Levy Kopelovich; Bert Vogelstein; Kenneth W Kinzler; Victor E Velculescu; Hai Yan
Identification of microbial DNA in human cancer.
BMC medical genomics 2009;2():22.
2008: V Rand; E Prebble; L Ridley; M Howard; W Wei; M-A Brundler; B E Fee; Gregory J Riggins; B Coyle; Richard G Grundy
Investigation of chromosome 1q reveals differential expression of members of the S100 family in clinical subgroups of intracranial paediatric ependymoma.
British journal of cancer 2008;99(7):1136-43.
2008: Joo-Mi Yi; Hsing-Chen Tsai; Sabine C Glöckner; Steven Lin; Joyce E Ohm; Hari Easwaran; C David James; Joseph F Costello; Gregory J Riggins; Charles G Eberhart; John Laterra; Angelo L Vescovi; NITA AHUJA; James G Herman; Kornel E Schuebel; Stephen B Baylin
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
Cancer research 2008;68(19):8094-103.
2008: I-Mei Siu; RENYUAN BAI; Gary L Gallia; Jennifer B Edwards; Betty M. Tyler; Charles G Eberhart; Gregory J Riggins
Coexpression of neuronatin splice forms promotes medulloblastoma growth.
Neuro-oncology 2008;10(5):716-24.
2008: DONALD PARSONS; Siân Jones; Xiaosong Zhang; Jimmy Cheng-Ho Lin; Rebecca J Leary; Philipp Angenendt; Parminder Mankoo; Hannah Carter; I-Mei Siu; Gary L Gallia; Alessandro Olivi; Roger McLendon; B Ahmed Rasheed; Stephen Keir; Tatiana Nikolskaya; Yuri Nikolsky; Dana A Busam; Hanna Tekleab; Luis Alberto Diaz; James Hartigan; Doug R Smith; Robert L Strausberg; Suely Kazue Nagahashi Marie; Sueli Mieko Oba Shinjo; Hai Yan; Gregory J Riggins; Darell D Bigner; Rachel Karchin; Nickolas Papadopoulos; Giovanni Parmigiani; Bert Vogelstein; Victor E Velculescu; Kenneth W Kinzler
An integrated genomic analysis of human glioblastoma multiforme.
Science (New York, N.Y.) 2008;321(5897):1807-12.
2008: Flavia R M Latini; Jefferson P Hemerly; Gisele Oler; Gregory J Riggins; Janete M Cerutti
Re-expression of ABI3-binding protein suppresses thyroid tumor growth by promoting senescence and inhibiting invasion.
Endocrine-related cancer 2008;15(3):787-99.
2008: Gisele Oler; Cléber P Camacho; Flávio C Hojaij; Pedro Michaluart; Gregory J Riggins; Janete M Cerutti
Gene expression profiling of papillary thyroid carcinoma identifies transcripts correlated with BRAF mutational status and lymph node metastasis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4735-42.
2008: Hector Alvarez; Alejandro Corvalan; Juan C Roa; Pedram Argani; Francisco Murillo; Jennifer Edwards; ROBERT BEATY; Georg Feldmann; Seung-Mo Hong; Michael Mullendore; Ivan Roa; Luis Ibañez; Fernando Pimentel; Alfonso Diaz; Gregory J Riggins; Anirban Maitra
Serial analysis of gene expression identifies connective tissue growth factor expression as a prognostic biomarker in gallbladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(9):2631-8.
2007: Janete M Cerutti; Gisele Oler; Pedro Michaluart; Rosana Delcelo; ROBERT BEATY; Jennifer Shoemaker; Gregory J Riggins
Molecular profiling of matched samples identifies biomarkers of papillary thyroid carcinoma lymph node metastasis.
Cancer research 2007;67(16):7885-92.
2007: ROBERT BEATY; Jennifer B Edwards; Kathy Boon; I-Mei Siu; James E Conway; Gregory J Riggins
PLXDC1 (TEM7) is identified in a genome-wide expression screen of glioblastoma endothelium.
Journal of neuro-oncology 2007;81(3):241-8.
2007: Kittisak Sawanyawisuth; Chaisiri Wongkham; Chawalit Pairojkul; O-Tur Saeseow; Gregory J Riggins; Norie Araki; Sopit Wongkham
Methionine aminopeptidase 2 over-expressed in cholangiocarcinoma: potential for drug target.
Acta oncologica (Stockholm, Sweden) 2007;46(3):378-85.
2007: Dimitri Trembath; Anita Lal; David Kroll; Nicholas H. Oberlies; Gregory J Riggins
A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII.
Molecular cancer 2007;6():30.
2006: Gary L Gallia; Vikki Rand; I-Mei Siu; Charles G Eberhart; C David James; Suely K N Marie; Sueli M Oba-Shinjo; Carlos Gilberto Carlotti; Otavia L Caballero; Andrew J G Simpson; Malcolm V Brock; Pierre P Massion; Benjamin S Carson; Gregory J Riggins
PIK3CA gene mutations in pediatric and adult glioblastoma multiforme.
Molecular cancer research : MCR 2006;4(10):709-14.
2006: Laura D Wood; Eric S Calhoun; Natalie Silliman; Janine Ptak; Stephen Szabo; Steve M Powell; Gregory J Riggins; Tian-Li Wang; Hai Yan; Adi F Gazdar; Scott E Kern; Len Pennacchio; Kenneth W Kinzler; Bert Vogelstein; Victor E Velculescu
Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers.
Human mutation 2006;27(10):1060-1.
2006: Vishwa Deep Dixit; Ashani T Weeraratna; Hyunwon Yang; Dorothy Bertak; Anthony Cooper-Jenkins; Gregory J Riggins; Charles G Eberhart; Dennis D Taub
Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility.
The Journal of biological chemistry 2006;281(24):16681-90.
2006: Janete M Cerutti; Flavia R M Latini; Claudia Nakabashi; Rosana Delcelo; Victor P Andrade; Marcelo João Amadei; Rui M B Maciel; Flávio C Hojaij; Donna Hollis; Jennifer Shoemaker; Gregory J Riggins
Diagnosis of suspicious thyroid nodules using four protein biomarkers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3311-8.
2006: Chris Hunter; Raffaella Smith; Daniel P Cahill; Philip Stephens; Claire Stevens; Jon Teague; Chris Greenman; Sarah Edkins; Graham Bignell; Helen Davies; Sarah O'Meara; Adrian Parker; Tim Avis; Syd Barthorpe; Lisa Brackenbury; Gemma Buck; Adam Butler; Jody Clements; Jennifer Cole; Ed Dicks; Simon Forbes; Matthew Gorton; Kristian Gray; Kelly Halliday; Rachel Harrison; Katy Hills; Jonathon Hinton; Andy Jenkinson; David Jones; Vivienne Kosmidou; Ross Laman; Richard Lugg; Andrew Menzies; Janet Perry; Robert Petty; Keiran Raine; David Richardson; Rebecca Shepherd; Alexandra Small; Helen Solomon; Calli Tofts; Jennifer Varian; Sofie West; Sara Caroline Widaa; Andy Yates; Douglas F Easton; Gregory J Riggins; Jennifer E Roy; Kymberly K Levine; Wolf Mueller; Tracy T Batchelor; David N Louis; Michael R Stratton; P Andrew Futreal; Richard Wooster
A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.
Cancer research 2006;66(8):3987-91.
2006: Chien-Tsun Kuan; Kenji Wakiya; Jeannette M Dowell; James E Herndon; David A Reardon; Michael W Graner; Gregory J Riggins; Carol J Wikstrand; Darell D Bigner
Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):1970-82.
2005: Asim S Siddiqui; Jaswinder Khattra; Allen D Delaney; Yongjun Zhao; Caroline Astell; Jennifer Asano; Ryan Babakaiff; Sarah Barber; Jaclyn Beland; Slavita Bohacec; Mabel Brown-John; Steve Chand; David Charest; Anita M Charters; Rebecca Cullum; Noreen Dhalla; Ruth Featherstone; Daniela S Gerhard; Brad Hoffman; Robert A Holt; Juan Hou; Byron Y-L Kuo; Lisa L C Lee; Stephanie Lee; Derek Leung; Kevin Ma; Corey Matsuo; Michael Mayo; Helen McDonald; Anna-liisa Prabhu; Pawan Pandoh; Gregory J Riggins; Teresa Ruiz de Algara; James L Rupert; Duane Smailus; Jeff Stott; Miranda Tsai; Richard Varhol; Pavle Vrljicak; David Wong; Mona K Wu; Yuan-Yun Xie; George Yang; Ida Zhang; Martin Hirst; Steven J M Jones; Cheryl D Helgason; Elizabeth M Simpson; Pamela A Hoodless; Marco A Marra
A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(51):18485-90.
2005: Vikki Rand; Jiaqi Huang; Tim Stockwell; Steve Ferriera; Oleksandr V Buzko; Samuel Levy; Dana Busam; Kelvin Li; Jennifer B Edwards; Charles G Eberhart; KATHLEEN MURPHY; Alexia Tsiamouri; Karen Beeson; Andrew J G Simpson; J Craig Venter; Gregory J Riggins; Robert L Strausberg
Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(40):14344-9.
2005: Ileana C Cuevas; Alison L Slocum; Peter Jun; Joseph F Costello; Andrew W Bollen; Gregory J Riggins; Michael W McDermott; Anita Lal
Meningioma transcript profiles reveal deregulated Notch signaling pathway.
Cancer research 2005;65(12):5070-5.
2005: Kathy Boon; Charles G Eberhart; Gregory J Riggins
Genomic amplification of orthodenticle homologue 2 in medulloblastomas.
Cancer research 2005;65(3):703-7.
2005: Carlos Pérez-Plasencia; Gregory J Riggins; Guelaguetza Vázquez-Ortiz; José Moreno; Hugo Arreola; Alfredo Hidalgo; Patricia Piña-Sanchez; Alfredo Hidalgo-Miranda
Characterization of the global profile of genes expressed in cervical epithelium by Serial Analysis of Gene Expression (SAGE).
BMC genomics 2005;6():130.
2004: Jun Lu; Anita Lal; Barry Merriman; Stan Nelson; Gregory J Riggins
A comparison of gene expression profiles produced by SAGE, long SAGE, and oligonucleotide chips.
Genomics 2004;84(4):631-6.
2004: Kathy Boon; Jennifer B Edwards; Charles G Eberhart; Gregory J Riggins
Identification of astrocytoma associated genes including cell surface markers.
BMC cancer 2004;4():39.
2004: Robert W Georgantas; Vivek Tanadve; Matthew T Malehorn; Shelly Heimfeld; Chen Chen; Laura Carr; Francisco Martinez-Murillo; Gregory J Riggins; Jeanne Kowalski; Curt I Civin
Microarray and serial analysis of gene expression analyses identify known and novel transcripts overexpressed in hematopoietic stem cells.
Cancer research 2004;64(13):4434-41.
2004: Kimberly L Blackwell; Mark Dewhirst; Vlayka B Liotcheva; Stacey Snyder; Gloria Broadwater; Rex Bentley; Anita Lal; Gregory J Riggins; Steve Anderson; James J Vredenburgh; Alan D Proia; Lyndsay N Harris
HER-2 gene amplification correlates with higher levels of angiogenesis and lower levels of hypoxia in primary breast tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 1):4083-8.
2004: Robert L Strausberg; Andrew J G Simpson; Lloyd J Old; Gregory J Riggins
Oncogenomics and the development of new cancer therapies.
Nature 2004;429(6990):469-74.
2004: Zhenghe Wang; Dong Shen; DONALD PARSONS; Alberto Bardelli; Jason A Sager; Stephen Szabo; Janine Ptak; Natalie Silliman; Brock A Peters; Michiel S van der Heijden; Giovanni Parmigiani; Hai Yan; Tian-Li Wang; Gregory J Riggins; Steven M Powell; James Willson; Sanford Markowitz; Kenneth W Kinzler; Bert Vogelstein; Victor E Velculescu
Mutational analysis of the tyrosine phosphatome in colorectal cancers.
Science (New York, N.Y.) 2004;304(5674):1164-6.
2004: Yardena Samuels; Zhenghe Wang; Alberto Bardelli; Natalie Silliman; Janine Ptak; Stephen Szabo; Hai Yan; Adi F Gazdar; Steven M Powell; Gregory J Riggins; James Willson; Sanford Markowitz; Kenneth W Kinzler; Bert Vogelstein; Victor E Velculescu
High frequency of mutations of the PIK3CA gene in human cancers.
Science (New York, N.Y.) 2004;304(5670):554.
2004: Janete M Cerutti; Rosana Delcelo; Marcelo João Amadei; Claudia Nakabashi; Rui M B Maciel; Bercedis Peterson; Jennifer Shoemaker; Gregory J Riggins
A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression.
The Journal of clinical investigation 2004;113(8):1234-42.
2004: Ashani T Weeraratna; Dorothea Becker; Kristen M Carr; Paul H Duray; Kevin P Rosenblatt; Sherry Yang; Yidong Chen; Michael Bittner; Robert L Strausberg; Gregory J Riggins; Urs Wagner; Olli Kallioniemi; Jeffrey M. Trent; Patrice J Morin; Paul S Meltzer
Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome.
Oncogene 2004;23(12):2264-74.
2004: Natanja Kirschbaum-Slager; Graziela M P Lopes; Pedro A F Galante; Gregory J Riggins; Sandro J de Souza
Splicing factors are differentially expressed in tumors.
Genetics and molecular research : GMR 2004;3(4):512-20.
2004: Ana Paula M Silva; Jorge E S de Souza; Pedro A F Galante; Gregory J Riggins; Sandro J de Souza; Anamaria A Camargo
The impact of SNPs on the interpretation of SAGE and MPSS experimental data.
Nucleic acids research 2004;32(20):6104-10.
2003: Helena Brentani; Otávia L Caballero; Anamaria A Camargo; Aline M da Silva; Wilson Araújo da Silva; Emmanuel Dias-Neto; Marco Grivet; Arthur Gruber; Pedro Edson Moreira Guimaraes; Winston Hide; Christian Iseli; Victor Jongeneel; Janet Kelso; Maria Aparecida Nagai; Elida Paula Benquique Ojopi; Elisson C Osorio; Eduardo M R Reis; Gregory J Riggins; Andrew John George Simpson; Sandro de Souza; Brian J Stevenson; Robert L Strausberg; Eloiza H Tajara; Sergio Verjovski-Almeida; Marcio Luis Acencio; Mário Henrique Bengtson; Fabiana Bettoni; Walter F Bodmer; Marcelo RS Briones; Luiz Paulo Camargo; Webster Cavenee; Janete M Cerutti; Luis Eduardo Coelho Andrade; Paulo César Costa dos Santos; Maria Cristina Ramos Costa; Israel Tojal da Silva; Marcos Roberto H Estécio; Karine Sa Ferreira; Frank B Furnari; Milton Faria; Pedro A F Galante; Gustavo S Guimaraes; Adriano Jesus Holanda; Edna Teruko Kimura; Maarten R Leerkes; Xin Lu; Rui M B Maciel; Elizabeth A L Martins; Katlin Brauer Massirer; Analy S A Melo; Carlos Alberto Mestriner; Elisabete Cristina Miracca; Leandro Lorenco Miranda; Francisco G Nobrega; Paulo S Oliveira; Apua C M Paquola; JOSÉ RODRIGO PANDOLFI; Maria Ines de Moura Campos Pardini; Fabio Passetti; John Quackenbush; Beatriz Schnabel; Mari Cleide Sogayar; Jorge E Souza; Sandro R Valentini; Andre C Zaiats; Elisabete Jorge Amaral; Liliane A T Arnaldi; Amelia Goes de Araújo; Simone Aparecida de Bessa; David C Bicknell; Maria Eugenia Ribeiro de Camaro; Dirce Maria Carraro; Helaine Carrer; Alex F Carvalho; Christian Colin; Fernando Costa; Cyntia Curcio; Ismael Dale Cotrim Guerreiro da Silva; Neusa Pereira da Silva; Márcia Dellamano; Hamza El-Dorry; Enilza Maria Espreafico; Ari José Scattone Ferreira; Cristiane Ayres Ferreira; Maria Angela H Z Fortes; Angelita Habr Gama; Daniel Giannella-Neto; Maria Lúcia C C Giannella; Ricardo R Giorgi; Gustavo Henrique Goldman; Maria Helena S Goldman; Christine Hackel; Paulo Lee Ho; Elza Myiuki Kimura; Luiz Paulo Kowalski; Jose E Krieger; Luciana C C Leite; Ademar Lopes; Ana Mercedes S C Luna; Alan Mackay; Suely Kazue Nagahashi Mari; Adriana Aparecida Marques; Waleska K Martins; André Montagnini; Mario Mourão Neto; Ana Lucia T O Nascimento; A Munro Neville; Marina P Nobrega; Mike J O'Hare; Audrey Yumi Otsuka; Anna Izabel Ruas de Melo; Maria Luisa Paco-Larson; Gonçalo Guimarães Pereira; Neusa Pereira da Silva; Joao Bosco Pesquero; Juliana Gilbert Pessoa; Paula Rahal; Claudia Aparecida Rainho; Vanderlei Rodrigues; Silvia Regina Rogatto; Camila Malta Romano; Janaina Gusmao Romeiro; Benedito Mauro Rossi; Monica Rusticci; Renata Guerra de Sá; Simone Cristina Sant' Anna; Miriam L Sarmazo; Teresa Cristina de Lima E Silva; Fernando Augusto Soares; Maria de Fátima Sonati; Josane de Freitas Sousa; Diana Queiroz; Valéria Valente; André Luiz Vettore; Fabiola Elizabeth Villanova; Marco Zago; Heloisa Zalcberg
The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13418-23.
2003: Kathy Boon; Jennifer B Edwards; I-Mei Siu; Deric Olschner; Charles G Eberhart; Marco A Marra; Robert L Strausberg; Gregory J Riggins
Comparison of medulloblastoma and normal neural transcriptomes identifies a restricted set of activated genes.
Oncogene 2003;22(48):7687-94.
2003: I-Mei Siu; Anita Lal; Jill R Blankenship; Naji Aldosari; Gregory J Riggins
c-Myc promoter activation in medulloblastoma.
Cancer research 2003;63(16):4773-6.
2003: Janete M Cerutti; Gregory J Riggins; Sandro J de Souza
What can digital transcript profiling reveal about human cancers?
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2003;36(8):975-85.
2003: Victor Jongeneel; Christian Iseli; Brian J Stevenson; Gregory J Riggins; Anita Lal; Alan Mackay; Robert A Harris; Michael J O'Hare; A Munro Neville; Andrew J G Simpson; Robert L Strausberg
Comprehensive sampling of gene expression in human cell lines with massively parallel signature sequencing.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4702-5.
2003: Dale Porter; Jaana Lahti-Domenici; Aparna Keshaviah; Young Kyung Bae; Pedram Argani; Jeffrey Marks; Andrea Richardson; Amiel Cooper; Robert L Strausberg; Gregory J Riggins; Stuart J Schnitt; Edward Gabrielson; Rebecca Gelman; Kornelia Polyak
Molecular markers in ductal carcinoma in situ of the breast.
Molecular cancer research : MCR 2003;1(5):362-75.
2003: Kathy Boon; Gregory J Riggins
SAGE as a strategy to isolate cancer-related genes.
Methods in molecular biology (Clifton, N.J.) 2003;222():463-79.
2002: Wa'el El-Rifai; Christopher A Moskaluk; Mohammad Khalouck Abdrabbo; Jeffery Harper; Cynthia Yoshida; Gregory J Riggins; Henry F Frierson; Steven M Powell
Gastric cancers overexpress S100A calcium-binding proteins.
Cancer research 2002;62(23):6823-6.
2002: Kathy Boon; Elisson C Osorio; Susan F Greenhut; Carl F Schaefer; Jennifer Shoemaker; Kornelia Polyak; Patrice J Morin; Kenneth H Buetow; Robert L Strausberg; Sandro J de Souza; Gregory J Riggins
An anatomy of normal and malignant gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(17):11287-92.
2002: Helen Davies; Graham R Bignell; Charles Cox; Philip Stephens; Sarah Edkins; Sheila Clegg; Jon Teague; Hayley Woffendin; Mathew J Garnett; William Bottomley; Neil Davis; Ed Dicks; Rebecca Ewing; Yvonne Floyd; Kristian Gray; Sarah Hall; Rachel Hawes; Jaime Hughes; Vivian Kosmidou; Andrew Menzies; Catherine Mould; Adrian Parker; Claire Stevens; Stephen Watt; Steven Hooper; Rebecca Wilson; Hiran Jayatilake; barry gusterson; Colin Cooper; Janet Shipley; Darren Hargrave; Katherine Pritchard-Jones; Norman Maitland; Georgia Chenevix-Trench; Gregory J Riggins; Darell D Bigner; Giuseppe Palmieri; Antonio Cossu; Adrienne Flanagan; Andrew Nicholson; Judy W C Ho; Suet Y Leung; Siu T Yuen; Barbara L Weber; Hilliard F Seigler; Timothy L Darrow; Hugh Paterson; Richard Marais; Christopher J Marshall; Richard Wooster; Michael R Stratton; P Andrew Futreal
Mutations of the BRAF gene in human cancer.
Nature 2002;417(6892):949-54.
2002: Anita Lal; Chad A Glazer; Holly M Martinson; Henry S Friedman; Gary E Archer; John H Sampson; Gregory J Riggins
Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion.
Cancer research 2002;62(12):3335-9.
2002: Robert L Strausberg; Anamaria A Camargo; Gregory J Riggins; Carl F Schaefer; Sandro J de Souza; Lynette H Grouse; A Lal; Kenneth H Buetow; Kathy Boon; Susan F Greenhut; Andrew J G Simpson
An international database and integrated analysis tools for the study of cancer gene expression.
The pharmacogenomics journal 2002;2(3):156-64.
2001: Robert L Strausberg; Gregory J Riggins
Navigating the human transcriptome.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(21):11837-8.
2001: A Lal; H Peters; B St Croix; Zishan A Haroon; Mark Dewhirst; Robert L Strausberg; J H Kaanders; A J van der Kogel; Gregory J Riggins
Transcriptional response to hypoxia in human tumors.
Journal of the National Cancer Institute 2001;93(17):1337-43.
2001: I-Mei Siu; Anita Lal; Gregory J Riggins
A database for regional gene expression in the human brain.
Brain research. Gene expression patterns 2001;1(1):33-8.
2001: Dale A Porter; Ian Krop; S Nasser; Dennis C Sgroi; Carolyn M Kaelin; Jeffrey R Marks; Gregory J Riggins; Kornelia Polyak
A SAGE (serial analysis of gene expression) view of breast tumor progression.
Cancer research 2001;61(15):5697-702.
2001: Kornelia Polyak; Gregory J Riggins
Gene discovery using the serial analysis of gene expression technique: implications for cancer research.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(11):2948-58.
2001: Thomas J Cummings; Christine M Hulette; Sandra H Bigner; Gregory J Riggins; Roger E McLendon
Ham56-immunoreactive macrophages in untreated infiltrating gliomas.
Archives of pathology & laboratory medicine 2001;125(5):637-41.
2001: Gregory J Riggins; Robert L Strausberg
Genome and genetic resources from the Cancer Genome Anatomy Project.
Human molecular genetics 2001;10(7):663-7.
2001: Huib N Caron; Barbera van Schaik; M van der Mee ; Frank Baas; Gregory J Riggins; Peter G van Sluis; Marie Christien Hermus; Ronald van Asperen; Kathy Boon; Paul A Voûte; Siem H Heisterkamp; Antoine H C van Kampen; Rogier Versteeg
The human transcriptome map: clustering of highly expressed genes in chromosomal domains.
Science (New York, N.Y.) 2001;291(5507):1289-92.
2001: Gregory J Riggins
Using Serial Analysis of Gene Expression to identify tumor markers and antigens.
Disease markers 2001;17(2):41-8.
2000: CD Hough; Cheryl A Sherman-Baust; Ellen S Pizer; Fredrick J Montz; Dwight D Im; Neil B Rosenshein; Kathleen R Cho; Gregory J Riggins; Patrice J Morin
Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancer.
Cancer research 2000;60(22):6281-7.
2000: William Loging; Anita Lal; I-Mei Siu; T L Loney; Carol J Wikstrand; Marco A Marra; C Prange; D D Bigner; Robert L Strausberg; Gregory J Riggins
Identifying potential tumor markers and antigens by database mining and rapid expression screening.
Genome research 2000;10(9):1393-402.
2000: Brad St Croix; Carlo Rago; Victor E Velculescu; Giovanni Traverso; Katharine E Romans; Elizabeth Montgomery; A Lal; Gregory J Riggins; Christoph Lengauer; Bert Vogelstein; Kenneth W Kinzler
Genes expressed in human tumor endothelium.
Science (New York, N.Y.) 2000;289(5482):1197-202.
2000: Alex E Lash; C M Tolstoshev; Lukas Wagner; Gerold Schuler; Robert L Strausberg; Gregory J Riggins; Stephen F Altschul
SAGEmap: a public gene expression resource.
Genome research 2000;10(7):1051-60.
1999: Anita Lal; I M Sui; Gregory J Riggins
Serial analysis of gene expression: probing transcriptomes for molecular targets.
Current opinion in molecular therapeutics 1999;1(6):720-6.
1999: Anita Lal; Alex E Lash; Stephen F Altschul; Victor E Velculescu; L Zhang; Roger E McLendon; Marco A Marra; C Prange; Patrice J Morin; Kornelia Polyak; Nickolas Papadopoulos; Bert Vogelstein; Kenneth W Kinzler; Robert L Strausberg; Gregory J Riggins
A public database for gene expression in human cancers.
Cancer research 1999;59(21):5403-7.
1999: Niels De Wind; Marleen Dekker; Nanna Claij; Léon Jansen; Y van Klink; M Radman; Gregory J Riggins; Martin van der Valk; K van't Wout; Hein te Riele
HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions.
Nature genetics 1999;23(3):359-62.
1998: Daniel P Cahill; Christoph Lengauer; J Yu; Gregory J Riggins; James Willson; Sanford D Markowitz; Kenneth W Kinzler; Bert Vogelstein
Mutations of mitotic checkpoint genes in human cancers.
Nature 1998;392(6673):300-3.
1998: Shibin Zhou; Phillip Buckhaults; L Zawel; Fred Bunz; Gregory J Riggins; J L Dai; Scott E Kern; Kenneth W Kinzler; Bert Vogelstein
Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2412-6.
1998: Kenji Okami; LI WU; Gregory J Riggins; Paul Cairns; Michael Goggins; Ella Evron; N Halachmi; Steven A Ahrendt; AL Reed; W Hilgers; Scott E Kern; Wayne M Koch; David Sidransky; Jin Jen
Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors.
Cancer research 1998;58(3):509-11.
1997: Gregory J Riggins; Kenneth W Kinzler; Bert Vogelstein; S Thiagalingam
Frequency of Smad gene mutations in human cancers.
Cancer research 1997;57(13):2578-80.
1996: Gregory J Riggins; S Thiagalingam; E Rozenblum; C L Weinstein; Scott E Kern; Stanley R Hamilton; James Willson; Sanford D Markowitz; Kenneth W Kinzler; Bert Vogelstein
Mad-related genes in the human.
Nature genetics 1996;13(3):347-9.
1995: Gregory J Riggins; Sanford Markowitz; J K Wilson; Bert Vogelstein; Kenneth W Kinzler
Absence of secretory phospholipase A2 gene alterations in human colorectal cancer.
Cancer research 1995;55(22):5184-6.
1994: Gregory J Riggins; F Zhang; Stephen Warren
Lack of imprinting of BCR.
Nature genetics 1994;6(3):226.
1994: Gregory J Riggins; Stephanie L Sherman; C N Phillips; W Stock; C A Westbrook; Stephen Warren
CGG-repeat polymorphism of the BCR gene rules out predisposing alleles leading to the Philadelphia chromosome.
Genes, chromosomes & cancer 1994;9(2):141-4.
1992: Gregory J Riggins; L K Lokey; Stephen Warren
CGG repeat polymorphism at the c-Ha-ras oncogene locus.
Human molecular genetics 1992;1(9):775.
1992: Gregory J Riggins; L K Lokey; J L Chastain; H A Leiner; Stephanie L Sherman; Keith Wilkinson; Stephen Warren
Human genes containing polymorphic trinucleotide repeats.
Nature genetics 1992;2(3):186-91.
1992: Gregory J Riggins; Stephanie L Sherman; Ben A Oostra; James S Sutcliffe; D Feitell; David L Nelson; B A van Oost; A P Smits; F J Ramos; E Pfendner
Characterization of a highly polymorphic dinucleotide repeat 150 KB proximal to the fragile X site.
American journal of medical genetics 1992;43(1-2):237-43.