FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Pascal Rigollier

Research Profile

Chemicals & Drugs

Procedures

Concepts & Ideas

Co-author Network

Publications

TOP 3
Andreas Boettcher; Simon Ruedisser; Paulus Erbel; Daniela Vinzenz; Nikolaus Schiering; Ulrich Hassiepen; Pascal Rigollier; Lorenz M Mayr; Julian Woelcke
Fragment-based screening by biochemical assays: Systematic feasibility studies with trypsin and MMP12.
Jürgen Maibaum; Stefan Stutz; Richard Göschke; Pascal Rigollier; Yasuchika Yamaguchi; Frederic Cumin; Joseph Rahuel; Hans-Peter Baum; Nissim-Claude Cohen; Christian R Schnell; Walter Fuhrer; Markus G Gruetter; Walter Schilling; Jeanette M Wood
Structural modification of the P2' position of 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: the discovery of aliskiren, a potent nonpeptide human renin inhibitor active after once daily dosing in marmosets.
Richard Göschke; Stefan Stutz; Vittorio Rasetti; Nissim-Claude Cohen; Joseph Rahuel; Pascal Rigollier; Hans-Peter Baum; Peter Forgiarini; Christian R Schnell; Trixie Wagner; Markus G Gruetter; Walter Fuhrer; Walter Schilling; Frederic Cumin; Jeanette M Wood; Jürgen Maibaum
Novel 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamide transition state peptidomimetics are potent and orally active inhibitors of human renin.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Pascal Rigollier (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2010: Andreas Boettcher; Simon Ruedisser; Paulus Erbel; Daniela Vinzenz; Nikolaus Schiering; Ulrich Hassiepen; Pascal Rigollier; Lorenz M Mayr; Julian Woelcke
Fragment-based screening by biochemical assays: Systematic feasibility studies with trypsin and MMP12.
Journal of biomolecular screening 2010;15(9):1029-41.
2007: Jürgen Maibaum; Stefan Stutz; Richard Göschke; Pascal Rigollier; Yasuchika Yamaguchi; Frederic Cumin; Joseph Rahuel; Hans-Peter Baum; Nissim-Claude Cohen; Christian R Schnell; Walter Fuhrer; Markus G Gruetter; Walter Schilling; Jeanette M Wood
Structural modification of the P2' position of 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: the discovery of aliskiren, a potent nonpeptide human renin inhibitor active after once daily dosing in marmosets.
Journal of medicinal chemistry 2007;50(20):4832-44.
2007: Richard Göschke; Stefan Stutz; Vittorio Rasetti; Nissim-Claude Cohen; Joseph Rahuel; Pascal Rigollier; Hans-Peter Baum; Peter Forgiarini; Christian R Schnell; Trixie Wagner; Markus G Gruetter; Walter Fuhrer; Walter Schilling; Frederic Cumin; Jeanette M Wood; Jürgen Maibaum
Novel 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamide transition state peptidomimetics are potent and orally active inhibitors of human renin.
Journal of medicinal chemistry 2007;50(20):4818-31.
2005: Edgar Jacoby; Ansgar Schuffenhauer; Maxim Popov; Kamal Azzaoui; Benjamin Havill; Ulrich Schopfer; Caroline Engeloch; Jaroslav Stanek; Pierre Acklin; Pascal Rigollier; Friederike Stoll; Guido Koch; Peter Meier; David Orain; Rudolph Giger; Jürgen Hinrichs; Karine Malagu; Jürg Zimmermann; Hans-Jörg Roth
Key aspects of the Novartis compound collection enhancement project for the compilation of a comprehensive chemogenomics drug discovery screening collection.
Current topics in medicinal chemistry 2005;5(4):397-411.
2004: Heinrich Rueeger; Marc Gerspacher; Peter Buehlmayer; Pascal Rigollier; Yasuchika Yamaguchi; Tibur Schmidlin; Steven Whitebread; Barbara Nuesslein-Hildesheim; Hanspeter Nick; Leoluca Cricione
Discovery and SAR of potent, orally available and brain-penetrable 5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen- and 4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen derivatives as neuropeptide Y Y5 receptor antagonists.
Bioorganic & medicinal chemistry letters 2004;14(10):2451-7.
2003: Jeanette M Wood; Jürgen Maibaum; Joseph Rahuel; Markus G Grütter; Nissim-Claude Cohen; Vittorio Rasetti; Heinrich Rüger; Richard Göschke; Stefan Stutz; Walter Fuhrer; Walter Schilling; Pascal Rigollier; Yasuchika Yamaguchi; Frederic Cumin; Hans-Peter Baum; Christian R Schnell; Peter Herold; Robert Mah; Chris Jensen; Eoin O'Brien; Alice Stanton; Martin P Bedigian
Structure-based design of aliskiren, a novel orally effective renin inhibitor.
Biochemical and biophysical research communications 2003;308(4):698-705.
2000: Heinrich Rueeger; Pascal Rigollier; Yasuchika Yamaguchi; Tibur Schmidlin; Walter Schilling; L Criscione; Steven Whitebread; Michele Chiesi; Mary Walker; Dale Dhanoa; Imadul Islam; J Zhang; Charles Gluchowski
Design, synthesis and SAR of a series of 2-substituted 4-amino-quinazoline neuropeptide Y Y5 receptor antagonists.
Bioorganic & medicinal chemistry letters 2000;10(11):1175-9.
1998: L Criscione; Pascal Rigollier; C Batzl-Hartmann; H Rüeger; Alain Stricker-Krongrad; P Wyss; L Brunner; Steven Whitebread; Yasuchika Yamaguchi; Christophe Gerald; R O Heurich; Mary Walker; Michele Chiesi; Walter Schilling; KG Hofbauer; N Levens
Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor.
The Journal of clinical investigation 1998;102(12):2136-45.