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Brien Riley

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T Bernard Bigdeli; Xiangning Chen; Ayman H Fanous; Kenneth S Kendler; Mark Reimers; Brien P Riley; Silviu-Alin Bacanu
On schizophrenia as a "disease of humanity".
M A Reimers; Brien P Riley; Gursharan Kalsi; D A Kertes; K S Kendler
Pathway based analysis of genotypes in relation to alcohol dependence.
Zhongming Zhao; John I Nurnberger; Brien P Riley; Marc A Schuckit; Edwin J C G van den Oord; Bradley T Webb; Arpana Agrawal; Fazil Aliev; Jill C Bettinger; Andrew G Davies; Danielle M Dick; Howard J Edenberg; Michael S Grotewiel; An-Yuan Guo; Peilin Jia; Kenneth S Kendler; John Kramer; Michael F Miles
Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study.

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All Publications

2013: T Bernard Bigdeli; Xiangning Chen; Ayman H Fanous; Kenneth S Kendler; Mark Reimers; Brien P Riley; Silviu-Alin Bacanu
On schizophrenia as a "disease of humanity".
Schizophrenia research 2013;143(1):223-4.
2012: M A Reimers; Brien P Riley; Gursharan Kalsi; D A Kertes; K S Kendler
Pathway based analysis of genotypes in relation to alcohol dependence.
The pharmacogenomics journal 2012;12(4):342-8.
2012: Zhongming Zhao; John I Nurnberger; Brien P Riley; Marc A Schuckit; Edwin J C G van den Oord; Bradley T Webb; Arpana Agrawal; Fazil Aliev; Jill C Bettinger; Andrew G Davies; Danielle M Dick; Howard J Edenberg; Michael S Grotewiel; An-Yuan Guo; Peilin Jia; Kenneth S Kendler; John Kramer; Michael F Miles
Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study.
BMC genomics 2012;13 Suppl 8():S16.
2011: Brion S Maher; Rebecca McNamee; Pierandrea Muglia; E Lenn Murrelle; John Nurnberger; Brien P Riley; Ralph E Tarter; Dawn L Thiselton; Jay A Tischfield; Vladimir I Vladimirov; Arpana Agrawal; Fazil Aliev; Tim B Bigdeli; Xiangning Chen; Howard D Chilcoat; Bernie Devlin; Danielle M Dick; Howard J Edenberg; Robert E Ferrell; Christian Heidbreder; John M Hettema; Moonsu Kang; Kenneth S Kendler; Galina P Kirillova; John Kramer; Shawn J Latendresse; Michael Vanyukov
The AVPR1A gene and substance use disorders: association, replication, and functional evidence.
Biological psychiatry 2011;70(6):519-27.
2011: Yu-Chu Chen; Kenneth S Kendler; Diana G Patterson; Carol A Prescott; Brien P Riley; Dermot Walsh; Po-Hsiu Kuo
Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.
Journal of studies on alcohol and drugs 2011;72(5):752-62.
2011: Jingchun Sun; Chunling Wan; Peilin Jia; Ayman H Fanous; Kenneth S Kendler; Brien P Riley; Zhongming Zhao
Application of systems biology approach identifies and validates GRB2 as a risk gene for schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample.
Schizophrenia research 2011;125(2-3):201-8.
2011: Laura M Hack; Gursharan Kalsi; Fazil Aliev; Po-Hsiu Kuo; Carol A Prescott; Diana G Patterson; Dermot Walsh; Danielle M Dick; Brien P Riley; Kenneth S Kendler
Limited associations of dopamine system genes with alcohol dependence and related traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD).
Alcoholism, clinical and experimental research 2011;35(2):376-85.
2010: Albert H Kim; Mark Reimers; Brion Maher; Vernell Williamson; Omari McMichael; Joseph L McClay; Edwin J C G van den Oord; Brien P Riley; Kenneth S Kendler; Vladimir I Vladimirov
MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders.
Schizophrenia research 2010;124(1-3):183-91.
2010: Gursharan Kalsi; Po-Hsiu Kuo; Fazil Aliev; Jeffry Alexander; Omari McMichael; Diana G Patterson; Dermot Walsh; Zhongming Zhao; Marc Schuckit; John Nurnberger; Howard Edenberg; John Kramer; Victor Hesselbrock; Jay A Tischfield; Vladimir Vladimirov; Carol A Prescott; Danielle M Dick; Kenneth S Kendler; Brien P Riley
A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Human molecular genetics 2010;19(12):2497-506.
2010: Sarah E Bergen; Ayman H Fanous; Po-Hsiu Kuo; Brandon K Wormley; F Anthony O'Neill; Dermot Walsh; Brien P Riley; Kenneth S Kendler
No association of dysbindin with symptom factors of schizophrenia in an Irish case-control sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(2):700-5.
2010: Dawn L Thiselton; Brion S Maher; Bradley T Webb; T B Bigdeli; F Anthony O'Neill; Dermot Walsh; Kenneth S Kendler; Brien P Riley
Association analysis of the PIP4K2A gene on chromosome 10p12 and schizophrenia in the Irish study of high density schizophrenia families (ISHDSF) and the Irish case-control study of schizophrenia (ICCSS).
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(1):323-31.
2010: Jingchun Sun; Peilin Jia; Ayman H Fanous; Edwin van den Oord; Xiangning Chen; Brien P Riley; Richard L Amdur; Kenneth S Kendler; Zhongming Zhao
Schizophrenia gene networks and pathways and their applications for novel candidate gene selection.
PloS one 2010;5(6):e11351.
2010: Brion S Maher; Mark A Reimers; Brien P Riley; Kenneth S Kendler
Allelic heterogeneity in genetic association meta-analysis: an application to DTNBP1 and schizophrenia.
Human heredity 2010;69(2):71-9.
2009: Po-Hsiu Kuo; Gursharan Kalsi; Carol A Prescott; Colin A Hodgkinson; David Goldman; Jeffry Alexander; Edwin J C G van den Oord; Xiangning Chen; Patrick F Sullivan; Diana G Patterson; Dermot Walsh; Kenneth S Kendler; Brien P Riley
Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence.
Drug and alcohol dependence 2009;101(1-2):80-7.
2009: E C Prom-Wormley; Lindon J Eaves; Debra L Foley; Charles O Gardner; K J Archer; B K Wormley; Hermine Maes; Brien P Riley; Judy L Silberg
Monoamine oxidase A and childhood adversity as risk factors for conduct disorder in females.
Psychological medicine 2009;39(4):579-90.
2009: vladimir vladimirov; Brion S Maher; Brandon Wormley; F Anthony O'Neill; Dermot Walsh; Kenneth S Kendler; Brien P Riley
The trace amine associated receptor (TAAR6) gene is not associated with schizophrenia in the Irish Case-Control Study of Schizophrenia (ICCSS) sample.
Schizophrenia research 2009;107(2-3):249-54.
2009: Gursharan Kalsi; Carol A Prescott; Kenneth S Kendler; Brien P Riley
Unraveling the molecular mechanisms of alcohol dependence.
Trends in genetics : TIG 2009;25(1):49-55.
2008: Jingchun Sun; Po-Hsiu Kuo; Brien P Riley; Kenneth S Kendler; Zhongming Zhao
Candidate genes for schizophrenia: a survey of association studies and gene ranking.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(7):1173-81.
2008: Brion S Maher; Brien P Riley; Kenneth S Kendler
Psychiatric genetics gets a boost.
Nature genetics 2008;40(9):1042-4.
2008: Ayman H Fanous; Michael C Neale; Bradley T Webb; Richard E Straub; F Anthony O'Neill; Dermot Walsh; Brien P Riley; Kenneth S Kendler
Novel linkage to chromosome 20p using latent classes of psychotic illness in 270 Irish high-density families.
Biological psychiatry 2008;64(2):121-7.
2008: Brien P Riley
Commentary on 'The case for gene-environment interactions in psychiatry'.
Current opinion in psychiatry 2008;21(4):324-5.
2008: Robin Page Goin-Kochel; Carla A Mazefsky; Brien P Riley
Level of functioning in autism spectrum disorders: phenotypic congruence among affected siblings.
Journal of autism and developmental disorders 2008;38(6):1019-27.
2008: Po-Hsiu Kuo; Gursharan Kalsi; Carol A Prescott; Colin A Hodgkinson; David Goldman; Edwin J van den Oord; Jeffry Alexander; Cizhong Jiang; Patrick F Sullivan; Diana G Patterson; Dermot Walsh; Kenneth S Kendler; Brien P Riley
Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.
Alcoholism, clinical and experimental research 2008;32(5):785-95.
2008: Dawn L Thiselton; vladimir vladimirov; Po-Hsiu Kuo; Joseph L McClay; Brandon Wormley; Ayman H Fanous; F Anthony O'Neill; Dermot Walsh; Edwin J C G van den Oord; Kenneth S Kendler; Brien P Riley
AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families.
Biological psychiatry 2008;63(5):449-57.
2007: George Moxley; Jinfeng Han; Alan G Stern; Brien P Riley
Potential influence of IL1B haplotype and IL1A-IL1B-IL1RN extended haplotype on hand osteoarthritis risk.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2007;15(10):1106-12.
2007: Ayman H Fanous; Michael C Neale; C O Gardner; Bradley T Webb; Richard E Straub; F Anthony O'Neill; Dermot Walsh; Brien P Riley; Kenneth S Kendler
Significant correlation in linkage signals from genome-wide scans of schizophrenia and schizotypy.
Molecular psychiatry 2007;12(10):958-65.
2007: V Vladimirov; Dawn L Thiselton; Po-Hsiu Kuo; Joseph L McClay; Ayman H Fanous; Brandon Wormley; Jen Vittum; R Ribble; B Moher; Edwin J C G van den Oord; F Anthony O'Neill; Dermot Walsh; Kenneth S Kendler; Brien P Riley
A region of 35 kb containing the trace amine associate receptor 6 (TAAR6) gene is associated with schizophrenia in the Irish study of high-density schizophrenia families.
Molecular psychiatry 2007;12(9):842-53.
2007: Ayman H Fanous; Michael C Neale; Bradley T Webb; Richard E Straub; Richard Amdur; F Anthony O'Neill; Dermot Walsh; Brien P Riley; Kenneth S Kendler
A genome-wide scan for modifier loci in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(5):589-95.
2007: Po-Hsiu Kuo; Michael C Neale; Brien P Riley; Diana G Patterson; Dermot Walsh; Carol A Prescott; Kenneth S Kendler
A genome-wide linkage analysis for the personality trait neuroticism in the Irish affected sib-pair study of alcohol dependence.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(4):463-8.
2006: Po-Hsiu Kuo; Michael C Neale; Brien P Riley; Bradley T Webb; Patrick F Sullivan; Jen Vittum; Diana G Patterson; Dawn L Thiselton; Edwin J C G van den Oord; Dermot Walsh; Kenneth S Kendler; Carol A Prescott
Identification of susceptibility loci for alcohol-related traits in the Irish Affected Sib Pair Study of Alcohol Dependence.
Alcoholism, clinical and experimental research 2006;30(11):1807-16.
2006: Brien P Riley; Gursharan Kalsi; Po-Hsiu Kuo; vladimir vladimirov; Dawn L Thiselton; Jen Vittum; Brandon Wormley; Michael S Grotewiel; Diana G Patterson; Patrick F Sullivan; Edwin J C G van den Oord; Dermot Walsh; Kenneth S Kendler; Carol A Prescott
Alcohol dependence is associated with the ZNF699 gene, a human locus related to Drosophila hangover, in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD) sample.
Molecular psychiatry 2006;11(11):1025-31.
2006: Carol A Prescott; Patrick F Sullivan; Po-Hsiu Kuo; Bradley T Webb; Jen Vittum; Diana G Patterson; Dawn L Thiselton; John M Myers; M Devitt; L J Halberstadt; V P Robinson; Michael C Neale; Edwin J C G van den Oord; Dermot Walsh; Brien P Riley; Kenneth S Kendler
Genomewide linkage study in the Irish affected sib pair study of alcohol dependence: evidence for a susceptibility region for symptoms of alcohol dependence on chromosome 4.
Molecular psychiatry 2006;11(6):603-11.
2005: Ayman H Fanous; Edwin J C G van den Oord; Brien P Riley; Steven H Aggen; Michael C Neale; F Anthony O'Neill; Dermot Walsh; Kenneth S Kendler
Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia.
The American journal of psychiatry 2005;162(10):1824-32.
2004: Dawn L Thiselton; Bradley T Webb; Benjamin M Neale; R C Ribble; F Anthony O'Neill; Dermot Walsh; Brien P Riley; Kenneth S Kendler
No evidence for linkage or association of neuregulin-1 (NRG1) with disease in the Irish study of high-density schizophrenia families (ISHDSF).
Molecular psychiatry 2004;9(8):777-83; image 729.
2003: Edwin J C G van den Oord; Patrick F Sullivan; Y Jiang; Dermot Walsh; F Anthony O'Neill; Kenneth S Kendler; Brien P Riley
Identification of a high-risk haplotype for the dystrobrevin binding protein 1 (DTNBP1) gene in the Irish study of high-density schizophrenia families.
Molecular psychiatry 2003;8(5):499-510.
2003: Edwin J C G van den Oord; Y Jiang; Brien P Riley; Kenneth S Kendler; Xiangning Chen
FP-TDI SNP scoring by manual and statistical procedures: a study of error rates and types.
BioTechniques 2003;34(3):610-6, 618-20, 622 passim.