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Kenneth Rinehart

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Procedures

Concepts & Ideas

Molecular Sequence Data

Living Beings

Phenomena

Magnetic Resonance Spectroscopy

Anatomy

Livers

Disorders

Drug-Induced Liver Injury

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Co-author Network

Co-Publications
Name
18
Wayne Carmichael
18
Michio Namikoshi
14
Kaarina Sivonen
10
Cornelis Grimmelikhuijzen
5
Val Beasley
4
Leo Rouhiainen
4
Hans-Peter Nothacker
3
A Otsuki
3
Scott Brittain
3
Elizabeth Jares-Erijman
3
Moucun Yuan
2
Mariyo Watanabe
2
Sandra Maria Feliciano de Oliveira Azevedo
2
Wanda Haschek
2
Glen Shaw

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Publications

TOP 3
Jie-Fei Cheng; Jong-Soo Lee; Furong Sun; Elizabeth Jares-Erijman; Sue Cross; Kenneth L Rinehart
Hamigerols A and B, unprecedented polysulfate sterol dimers from the Mediterranean sponge Hamigera hamigera.
Jie-Fei Cheng; Jong-Soo Lee; Ryuichi Sakai; Elizabeth Jares-Erijman; Maria V Silva; Kenneth L Rinehart
Myriaporones 1-4, cytotoxic metabolites from the Mediterranean bryozoan Myriapora truncata.
Val R Beasley; Sally J Bruno; John S Burner; Byoung W Choi; Kenneth L Rinehart; Gary D Koritz; Jeffrey M Levengood
Fate of tritiated didemnin B in mice: excretion and tissue concentrations after an intraperitoneal dose.

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All Publications

2007: Jie-Fei Cheng; Jong-Soo Lee; Furong Sun; Elizabeth Jares-Erijman; Sue Cross; Kenneth L Rinehart
Hamigerols A and B, unprecedented polysulfate sterol dimers from the Mediterranean sponge Hamigera hamigera.
Journal of natural products 2007;70(7):1195-9.
2007: Jie-Fei Cheng; Jong-Soo Lee; Ryuichi Sakai; Elizabeth Jares-Erijman; Maria V Silva; Kenneth L Rinehart
Myriaporones 1-4, cytotoxic metabolites from the Mediterranean bryozoan Myriapora truncata.
Journal of natural products 2007;70(3):332-6.
2005: Val R Beasley; Sally J Bruno; John S Burner; Byoung W Choi; Kenneth L Rinehart; Gary D Koritz; Jeffrey M Levengood
Fate of tritiated didemnin B in mice: excretion and tissue concentrations after an intraperitoneal dose.
Biopharmaceutics & drug disposition 2005;26(8):341-51.
2003: Isabelle Bonnard; Ignacio Manzanares; Kenneth L Rinehart
Stereochemistry of kahalalide F.
Journal of natural products 2003;66(11):1466-70.
2003: Virginia K B Lehmann; Audris Huang; Sandra Ibanez-Calero; G R Wilson; Kenneth L Rinehart
Illudin S, the sole antiviral compound in mature fruiting bodies of Omphalotus illudens.
Journal of natural products 2003;66(9):1257-8.
2002: Sandra Maria Feliciano de Oliveira Azevedo; Wayne W Carmichael; Elise M Jochimsen; Kenneth L Rinehart; Sharon Lau; Glen R Shaw; Geoff Eaglesham
Human intoxication by microcystins during renal dialysis treatment in Caruaru-Brazil.
Toxicology 2002;181-182():441-6.
2002: Jesper Laub; Peter Henriksen; Scott M Brittain; Jim Wang; Wayne W Carmichael; Kenneth L Rinehart; Ojvind Moestrup
[ADMAdda5]-microcystins in Planktothrix agardhii strain PH-123 (cyanobacteria)--importance for monitoring of microcystins in the environment.
Environmental toxicology 2002;17(4):351-7.
2001: Wayne W Carmichael; Sandra Maria Feliciano de Oliveira Azevedo; J S An; R J Molica; Elise M Jochimsen; S Lau; Kenneth L Rinehart; Glen R Shaw; Geoff Eaglesham
Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins.
Environmental health perspectives 2001;109(7):663-8.
2000: Scott M Brittain; Zakaria A Mohamed; J Wang; V K Lehmann; Wayne W Carmichael; Kenneth L Rinehart
Isolation and characterization of microcystins from a river nile strain of Oscillatoria tenuis Agardh ex Gomont.
Toxicon : official journal of the International Society on Toxinology 2000;38(12):1759-71.
2000: C Pearson; Kenneth L Rinehart; M Sugano; J R Costerison
Enantiospecific synthesis of N-Boc-Adda: a linear approach.
Organic letters 2000;2(18):2901-3.
2000: Kenneth L Rinehart
Antitumor compounds from tunicates.
Medicinal research reviews 2000;20(1):1-27.
1999: Moucun Yuan; Michio Namikoshi; A Otsuki; Mariyo F Watanabe; Kenneth L Rinehart
Electrospray ionization mass spectrometric analysis of microcystins, cyclic heptapeptide hepatotoxins: modulation of charge states and [M + H]+ to [M + Na]+ ratio.
Journal of the American Society for Mass Spectrometry 1999;10(11):1138-51.
1999: Moucun Yuan; Michio Namikoshi; A Otsuki; Kenneth L Rinehart; Kaarina Sivonen; Mariyo F Watanabe
Low-energy collisionally activated decomposition and structural characterization of cyclic heptapeptide microcystins by electrospray ionization mass spectrometry.
Journal of mass spectrometry : JMS 1999;34(1):33-43.
1998: Michio Namikoshi; Moucun Yuan; Kaarina Sivonen; Wayne W Carmichael; Kenneth L Rinehart; Leo Rouhiainen; F Sun; Scott M Brittain; A Otsuki
Seven new microcystins possessing two L-glutamic acid units, isolated from Anabaena sp. strain 186.
Chemical research in toxicology 1998;11(2):143-9.
1997: A Moosler; Kenneth L Rinehart; Cornelis J P Grimmelikhuijzen
Isolation of three novel neuropeptides, the Cyanea-RFamides I-III, from Scyphomedusae.
Biochemical and biophysical research communications 1997;236(3):743-9.
1997: R R Stotts; AR Twardock; Wanda M Haschek; Byoung W Choi; Kenneth L Rinehart; Val R Beasley
Distribution of tritiated dihydromicrocystin in swine.
Toxicon : official journal of the International Society on Toxinology 1997;35(6):937-53.
1996: A Moosler; Kenneth L Rinehart; Cornelis J P Grimmelikhuijzen
Isolation of four novel neuropeptides, the hydra-RFamides I-IV, from Hydra magnipapillata.
Biochemical and biophysical research communications 1996;229(2):596-602.
1996: Heather Sings; K C Bible; Kenneth L Rinehart
Acyl tunichlorins: a new class of nickel chlorins isolated from the Caribbean tunicate Trididemnum solidum.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):10560-5.
1996: R Sakai; Kenneth L Rinehart; V Kishore; Bijoy Kundu; Glynn Faircloth; J B Gloer; J R Carney; Michio Namikoshi; F Sun; R G Hughes; D García Grávalos; T G de Quesada; G R Wilson; R M Heid
Structure--activity relationships of the didemnins.
Journal of medicinal chemistry 1996;39(14):2819-34.
1995: J R Carney; Kenneth L Rinehart
Biosynthesis of brominated tyrosine metabolites by Aplysina fistularis.
Journal of natural products 1995;58(7):971-85.
1995: J N McGuire; S R Wilson; Kenneth L Rinehart
Cremeomycin, a novel cytotoxic antibiotic from Streptomyces cremeus. Structure elucidation and biological activity.
The Journal of antibiotics 1995;48(6):516-9.
1994: R C Lau; Kenneth L Rinehart
Berninamycins B, C, and D, minor metabolites from Streptomyces bernensis.
The Journal of antibiotics 1994;47(12):1466-72.
1994: E S Adams; Kenneth L Rinehart
Directed biosynthesis of 5"-fluoropactamycin in Streptomyces pactum.
The Journal of antibiotics 1994;47(12):1456-65.
1994: A L Staley; Kenneth L Rinehart
Spectomycins, new antibacterial compounds produced by Streptomyces spectabilis: isolation, structures, and biosynthesis.
The Journal of antibiotics 1994;47(12):1425-33.
1994: R Luukkainen; Michio Namikoshi; Kaarina Sivonen; Kenneth L Rinehart; S I Niemelä
Isolation and identification of 12 microcystins from four strains and two bloom samples of Microcystis spp.: structure of a new hepatotoxin.
Toxicon : official journal of the International Society on Toxinology 1994;32(1):133-9.
1993: Elizabeth Jares-Erijman; A A Ingrum; F Sun; Kenneth L Rinehart
On the structures of crambescins B and C1.
Journal of natural products 1993;56(12):2186-8.
1993: S E DeVries; Michio Namikoshi; Frank D Galey; J E Merritt; Kenneth L Rinehart; Val R Beasley
Chemical study of the hepatotoxins from Microcystis aeruginosa collected in California.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 1993;5(3):409-12.
1993: R Luukkainen; Kaarina Sivonen; Michio Namikoshi; M Färdig; Kenneth L Rinehart; S I Niemelä
Isolation and identification of eight microcystins from thirteen Oscillatoria agardhii strains and structure of a new microcystin.
Applied and environmental microbiology 1993;59(7):2204-9.
1993: R R Stotts; Michio Namikoshi; Wanda M Haschek; Kenneth L Rinehart; Wayne W Carmichael; A M Dahlem; Val R Beasley
Structural modifications imparting reduced toxicity in microcystins from Microcystis spp.
Toxicon : official journal of the International Society on Toxinology 1993;31(6):783-9.
1993: K Carstensen; I D McFarlane; Kenneth L Rinehart; D Hudman; F Sun; Cornelis J P Grimmelikhuijzen
Isolation of
Peptides 1993;14(2):131-5.

1993: Michio Namikoshi; B W Choi; F Sun; Kenneth L Rinehart; W R Evans; Wayne W Carmichael
Chemical characterization and toxicity of dihydro derivatives of nodularin and microcystin-LR, potent cyanobacterial cyclic peptide hepatotoxins.
Chemical research in toxicology 1993;6(2):151-8.
1992: R Sakai; Kenneth L Rinehart; Y Guan; A H Wang
Additional antitumor ecteinascidins from a Caribbean tunicate: crystal structures and activities in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11456-60.
1992: Kaarina Sivonen; Michio Namikoshi; W R Evans; B V Gromov; Wayne W Carmichael; Kenneth L Rinehart
Isolation and structures of five microcystins from a Russian Microcystis aeruginosa strain CALU 972.
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1481-5.
1992: Michio Namikoshi; Kaarina Sivonen; W R Evans; F Sun; Wayne W Carmichael; Kenneth L Rinehart
Isolation and structures of microcystins from a cyanobacterial water bloom (Finland).
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1473-9.
1992: Kaarina Sivonen; O M Skulberg; Michio Namikoshi; W R Evans; Wayne W Carmichael; Kenneth L Rinehart
Two methyl ester derivatives of microcystins, cyclic heptapeptide hepatotoxins, isolated from Anabaena flos-aquae strain CYA 83/1.
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1465-71.
1992: Michio Namikoshi; Kaarina Sivonen; W R Evans; Wayne W Carmichael; F Sun; Leo Rouhiainen; R Luukkainen; Kenneth L Rinehart
Two new L-serine variants of microcystins-LR and -RR from Anabaena sp. strains 202 A1 and 202 A2.
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1457-64.
1992: K Carstensen; Kenneth L Rinehart; I D McFarlane; Cornelis J P Grimmelikhuijzen
Isolation of Leu-Pro-Pro-Gly-Pro-Leu-Pro-Arg-Pro-NH2 (Antho-RPamide), an N-terminally protected, biologically active neuropeptide from sea anemones.
Peptides 1992;13(5):851-7.
1992: Michio Namikoshi; Kaarina Sivonen; W R Evans; Wayne W Carmichael; Leo Rouhiainen; R Luukkainen; Kenneth L Rinehart
Structures of three new homotyrosine-containing microcystins and a new homophenylalanine variant from Anabaena sp. strain 66.
Chemical research in toxicology 1992;5(5):661-6.
1992: J Kiviranta; Michio Namikoshi; Kaarina Sivonen; W R Evans; Wayne W Carmichael; Kenneth L Rinehart
Structure determination and toxicity of a new microcystin from Microcystis aeruginosa strain 205.
Toxicon : official journal of the International Society on Toxinology 1992;30(9):1093-8.
1992: Kaarina Sivonen; Michio Namikoshi; W R Evans; Wayne W Carmichael; F Sun; Leo Rouhiainen; R Luukkainen; Kenneth L Rinehart
Isolation and characterization of a variety of microcystins from seven strains of the cyanobacterial genus Anabaena.
Applied and environmental microbiology 1992;58(8):2495-500.
1992: Kaarina Sivonen; Michio Namikoshi; W R Evans; M Färdig; Wayne W Carmichael; Kenneth L Rinehart
Three new microcystins, cyclic heptapeptide hepatotoxins, from Nostoc sp. strain 152.
Chemical research in toxicology 1992;5(4):464-9.
1992: Cornelis J P Grimmelikhuijzen; Kenneth L Rinehart; A N Spencer
Isolation of the neuropeptide less than Glu-Trp-Leu-Lys-Gly-Arg-Phe-NH2 (Pol-RFamide II) from the hydromedusa Polyorchis penicillatus.
Biochemical and biophysical research communications 1992;183(2):375-82.
1992: Cornelis J P Grimmelikhuijzen; D Darmer; C Schmutzler; K Carstensen; A Moosler; Hans-Peter Nothacker; Rainer K Reinscheid; H Vollert; Kenneth L Rinehart; I D McFarlane
The peptidergic nervous system of coelenterates.
Progress in brain research 1992;92():137-48.
1992: Kenneth L Rinehart
Secondary metabolites from marine organisms.
Ciba Foundation symposium 1992;171():236-49; discussion 249-54.
1991: Hans-Peter Nothacker; Kenneth L Rinehart; I D McFarlane; Cornelis J P Grimmelikhuijzen
Isolation of two novel neuropeptides from sea anemones: the unusual, biologically active L-3-phenyllactyl-Tyr-Arg-Ile-NH2 and its des-phenyllactyl fragment Tyr-Arg-Ile-NH2.
Peptides 1991;12(6):1165-73.
1991: Hans-Peter Nothacker; Kenneth L Rinehart; Cornelis J P Grimmelikhuijzen
Isolation of L-3-phenyllactyl-Phe-Lys-Ala-NH2 (Antho-KAamide), a novel neuropeptide from sea anemones.
Biochemical and biophysical research communications 1991;179(3):1205-11.
1991: R G Ankenbauer; A L Staley; Kenneth L Rinehart; CD Cox
Mutasynthesis of siderophore analogues by Pseudomonas aeruginosa.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(5):1878-82.
1991: A L Staley; Kenneth L Rinehart
Biosynthesis of the streptovaricins: 3-amino-5-hydroxybenzoic acid as a precursor to the meta-C7N unit.
The Journal of antibiotics 1991;44(2):218-24.
1990: Kaarina Sivonen; Wayne W Carmichael; Michio Namikoshi; Kenneth L Rinehart; A M Dahlem; S I Niemelä
Isolation and characterization of hepatotoxic microcystin homologs from the filamentous freshwater cyanobacterium Nostoc sp. strain 152.
Applied and environmental microbiology 1990;56(9):2650-7.
1990: Kenneth L Rinehart; Tom Holt; N L Fregeau; P A Keifer; G R Wilson; T J Perun; R Sakai; A G Thompson; J G Stroh; L S Shield
Bioactive compounds from aquatic and terrestrial sources.
Journal of natural products 1990;53(4):771-92.
1990: Cornelis J P Grimmelikhuijzen; Kenneth L Rinehart; E Jacob; D Graff; Rainer K Reinscheid; Hans-Peter Nothacker; A L Staley
Isolation of L-3-phenyllactyl-Leu-Arg-Asn-NH2 (Antho-RNamide), a sea anemone neuropeptide containing an unusual amino-terminal blocking group.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(14):5410-4.
1989: Kaarina Sivonen; K Kononen; Wayne W Carmichael; A M Dahlem; Kenneth L Rinehart; J Kiviranta; S I Niemela
Occurrence of the hepatotoxic cyanobacterium Nodularia spumigena in the Baltic Sea and structure of the toxin.
Applied and environmental microbiology 1989;55(8):1990-5.
1988: Cornelis J P Grimmelikhuijzen; M Hahn; Kenneth L Rinehart; A N Spencer
Isolation of pyroGlu-Leu-Leu-Gly-Gly-Arg-Phe-NH2 (Pol-RFamide), a novel neuropeptide from hydromedusae.
Brain research 1988;475(1):198-203.
1988: R G Ankenbauer; T Toyokuni; A Staley; Kenneth L Rinehart; CD Cox
Synthesis and biological activity of pyochelin, a siderophore of Pseudomonas aeruginosa.
Journal of bacteriology 1988;170(11):5344-51.
1988: K C Bible; M Buytendorp; P D Zierath; Kenneth L Rinehart
Tunichlorin: a nickel chlorin isolated from the Caribbean tunicate Trididemnum solidum.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4582-6.
1988: Kenneth L Rinehart; V Kishore; K C Bible; R Sakai; D W Sullins; K M Li
Didemnins and tunichlorin: novel natural products from the marine tunicate Trididemnum solidum.
Journal of natural products 1988;51(1):1-21.
1988: Ken-Ichi Harada; M Suzuki; A M Dahlem; Val R Beasley; Wayne W Carmichael; Kenneth L Rinehart
Improved method for purification of toxic peptides produced by cyanobacteria.
Toxicon : official journal of the International Society on Toxinology 1988;26(5):433-9.
1984: J C Escalante-Semerena; J A Leigh; Kenneth L Rinehart; RS Wolfe
Formaldehyde activation factor, tetrahydromethanopterin, a coenzyme of methanogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(7):1976-80.
1983: Kenneth L Rinehart; J B Gloer; G R Wilson; R G Hughes; L H Li; H E Renis; J P McGovren
Antiviral and antitumor compounds from tunicates.
Federation proceedings 1983;42(1):87-90.
1981: Kenneth L Rinehart; J B Gloer; R G Hughes; H E Renis; J P McGovren; E B Swynenberg; D A Stringfellow; S L Kuentzel; L H Li
Didemnins: antiviral and antitumor depsipeptides from a caribbean tunicate.
Science (New York, N.Y.) 1981;212(4497):933-5.

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