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Marvin Rittenberg

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gregory wiens; McKay Brown; Marvin B Rittenberg
Repertoire shift in the humoral response to phosphocholine-keyhole limpet hemocyanin: VH somatic mutation in germinal center B cells impairs T15 Ig function.
Elizabeth A Whitcomb; Tammy M Martin; Marvin B Rittenberg
Restoration of Ig secretion: mutation of germline-encoded residues in T15L chains leads to secretion of free light chains and assembled antibody complexes bearing secretion-impaired heavy chains.
gregory wiens; Thomas O'Hare; Marvin B Rittenberg
Recovering antibody secretion using a hapten ligand as a chemical chaperone.

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All Publications

2003: gregory wiens; McKay Brown; Marvin B Rittenberg
Repertoire shift in the humoral response to phosphocholine-keyhole limpet hemocyanin: VH somatic mutation in germinal center B cells impairs T15 Ig function.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):5095-102.
2003: Elizabeth A Whitcomb; Tammy M Martin; Marvin B Rittenberg
Restoration of Ig secretion: mutation of germline-encoded residues in T15L chains leads to secretion of free light chains and assembled antibody complexes bearing secretion-impaired heavy chains.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):1903-9.
2001: gregory wiens; Thomas O'Hare; Marvin B Rittenberg
Recovering antibody secretion using a hapten ligand as a chemical chaperone.
The Journal of biological chemistry 2001;276(44):40933-9.
2001: gregory wiens; A Lekkerkerker; I Veltman; Marvin B Rittenberg
Mutation of a single conserved residue in VH complementarity-determining region 2 results in a severe Ig secretion defect.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):2179-86.
2001: Susan E Murray; H R Lallman; AD Heard; Marvin B Rittenberg; Mary P Stenzel-Poore
A genetic model of stress displays decreased lymphocytes and impaired antibody responses without altered susceptibility to Streptococcus pneumoniae.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(2):691-8.
2000: McKay Brown; Maria A Schumacher; gregory wiens; Richard G Brennan; Marvin B Rittenberg
The structural basis of repertoire shift in an immune response to phosphocholine.
The Journal of experimental medicine 2000;191(12):2101-12.
2000: Sarah C Coste; R A Kesterson; KA Heldwein; Susan L Stevens; AD Heard; Jacob Hollis; Susan E Murray; Jennifer K Hill; George A Pantely; Alan Roger (Roger) Hohimer; D C Hatton; Tamara J Phillips; Deborah A Finn; Malcolm J Low; Marvin B Rittenberg; Peter Stenzel; Mary P Stenzel-Poore
Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2.
Nature genetics 2000;24(4):403-9.
1999: Thomas O'Hare; gregory wiens; Elizabeth A Whitcomb; Caroline A Enns; Marvin B Rittenberg
Cutting edge: proteasome involvement in the degradation of unassembled Ig light chains.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):11-4.
1999: McKay Brown; gregory wiens; Thomas O'Hare; Mary P Stenzel-Poore; Marvin B Rittenberg
Replacements in the exposed loop of the T15 antibody VH CDR2 affect carrier recognition of PC-containing pathogens.
Molecular immunology 1999;36(3):205-11.
1998: Thomas O'Hare; Marvin B Rittenberg
A simple method for determining K(A)s of both low and high affinity IgG antibodies.
Journal of immunological methods 1998;218(1-2):161-7.
1998: Tammy M Martin; gregory wiens; Marvin B Rittenberg
Inefficient assembly and intracellular accumulation of antibodies with mutations in V(H) CDR2.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):5963-70.
1998: gregory wiens; V A Roberts; Elizabeth A Whitcomb; Thomas O'Hare; Mary P Stenzel-Poore; Marvin B Rittenberg
Harmful somatic mutations: lessons from the dark side.
Immunological reviews 1998;162():197-209.
1997: KA Heldwein; J E Duncan; Peter Stenzel; Marvin B Rittenberg; Mary P Stenzel-Poore
Endotoxin regulates corticotropin-releasing hormone receptor 2 in heart and skeletal muscle.
Molecular and cellular endocrinology 1997;131(2):167-72.
1997: gregory wiens; KA Heldwein; Mary P Stenzel-Poore; Marvin B Rittenberg
Somatic mutation in VH complementarity-determining region 2 and framework region 2: differential effects on antigen binding and Ig secretion.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(3):1293-302.
1996: Tammy M Martin; C Kowalczyk; S Stevens; gregory wiens; Mary P Stenzel-Poore; Marvin B Rittenberg
Deletion in HCDR3 rescues T15 antibody mutants from a secretion defect caused by mutations in HCDR2.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4341-6.
1996: KA Heldwein; D L Redick; Marvin B Rittenberg; W C Claycomb; Mary P Stenzel-Poore
Corticotropin-releasing hormone receptor expression and functional coupling in neonatal cardiac myocytes and AT-1 cells.
Endocrinology 1996;137(9):3631-9.
1996: Mary P Stenzel-Poore; J E Duncan; Marvin B Rittenberg; Antony C (Tony) Bakke; Stephen C Heinrichs
CRH overproduction in transgenic mice: behavioral and immune system modulation.
Annals of the New York Academy of Sciences 1996;780():36-48.
1996: E Barbar; Tammy M Martin; M Brown; Marvin B Rittenberg; David H Peyton
Binding of phenylphosphocholine-carrier conjugates to the combining site of antibodies maintains a conformation of the hapten.
Biochemistry 1996;35(9):2958-67.
1995: Qing C Chen; V A Roberts; S Stevens; M Brown; Mary P Stenzel-Poore; Marvin B Rittenberg
Enhancement and destruction of antibody function by somatic mutation: unequal occurrence is controlled by V gene combinatorial associations.
The EMBO journal 1995;14(12):2784-94.
1995: Peter Stenzel; RA Kesterson; W Yeung; Roger D Cone; Marvin B Rittenberg; Mary P Stenzel-Poore
Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart.
Molecular endocrinology (Baltimore, Md.) 1995;9(5):637-45.
1994: Qing C Chen; Tammy M Martin; S Stevens; Marvin B Rittenberg
Defective secretion of an immunoglobulin caused by mutations in the heavy chain complementarity determining region 2.
The Journal of experimental medicine 1994;180(2):577-86.
1992: Qing C Chen; V A Roberts; Marvin B Rittenberg
Generation and analysis of random point mutations in an antibody CDR2 sequence: many mutated antibodies lose their ability to bind antigen.
The Journal of experimental medicine 1992;176(3):855-66.
1992: Qing C Chen; U Bruderer; Marvin B Rittenberg
The developmental patterns of B cell precursors distinguishing between environmental and nonenvironmental forms of phosphocholine.
Cellular immunology 1992;143(2):378-88.
1992: U Bruderer; David H Peyton; E Barbar; J H Fellman; Marvin B Rittenberg
Hapten conformation in the combining site of antibodies that bind phenylphosphocholine.
Biochemistry 1992;31(2):584-9.
1992: M Brown; Mary P Stenzel-Poore; S Stevens; S K Kondoleon; John D Ng; Hans Peter Bächinger; Marvin B Rittenberg
Immunologic memory to phosphocholine keyhole limpet hemocyanin. Recurrent mutations in the lambda 1 light chain increase affinity for antigen.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(2):339-46.
1991: Qing C Chen; Mary P Stenzel-Poore; Marvin B Rittenberg
Natural auto- and polyreactive antibodies differing from antigen-induced antibodies in the H chain CDR3.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(7):2359-67.
1991: Abigail C Buenafe; Marvin B Rittenberg
Maturation of the antibody response to a protein-coupled form of the organophosphorus toxin soman.
Immunology 1991;73(4):398-406.
1989: Mary P Stenzel-Poore; Marvin B Rittenberg
Clonal diversity, somatic mutation, and immune memory to phosphocholine-keyhole limpet hemocyanin.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(12):4123-33.
1989: T V Tittle; M Brown; Marvin B Rittenberg
Characterization of lambda class antibodies from the BALB/c memory response to a [glucosyl-alpha(1----3) glucosyl]-protein conjugate.
Molecular immunology 1989;26(9):809-17.
1989: Abigail C Buenafe; F F Makowski; Marvin B Rittenberg
Molecular analysis and fine specificity of antibodies against an organophosphorus hapten.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(2):539-45.
1989: U Bruderer; Mary P Stenzel-Poore; Hans Peter Bächinger; J H Fellman; Marvin B Rittenberg
Antibody combining site heterogeneity within the response to phosphocholine-keyhole limpet hemocyanin.
Molecular immunology 1989;26(1):63-71.
1988: Mary P Stenzel-Poore; U Bruderer; Marvin B Rittenberg
The adaptive potential of the memory response: clonal recruitment and epitope recognition.
Immunological reviews 1988;105():113-36.
1987: Mary P Stenzel-Poore; T J Hall; C H Heusser; C H Faust; Marvin B Rittenberg
Immunologic memory to PC-KLH: participation of the Q52 VH gene family.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(5):1698-703.
1987: Abigail C Buenafe; Marvin B Rittenberg
Combining site specificity of monoclonal antibodies to the organophosphate hapten soman.
Molecular immunology 1987;24(5):401-7.
1987: Mary P Stenzel-Poore; Marvin B Rittenberg
Immunoglobulin variable region heptamer-nonamer recognition sequence joined to rearranged D-J segment: implications for the immunoglobulin recombinase mechanism.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(9):3055-9.
1986: T J Hall; Marvin B Rittenberg
The interaction of monomeric and complexed mouse monoclonal IgG with rat basophilic leukemia cells: a subset of IgG molecules can bind to RBL cell Fc receptors for IgG.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(7):2331-8.
1986: F Makowski; M I Joffe; Marvin B Rittenberg
Single cell cloning of Epstein-Barr virus transformed cells in 20-microliter hanging drops.
Journal of immunological methods 1986;90(1):85-7.
1986: Marvin B Rittenberg; R W Glanville; R H Aebersold; S P Chang; M Brown
Immunologic memory to phosphorylcholine (PC). VIII. Expression of the VH-12 gene product in the response to PC-keyhole limpet hemocyanin.
European journal of immunology 1986;16(5):503-7.
1986: Marvin B Rittenberg; Abigail C Buenafe; M Brown
A simple method for cloning hybridomas in 20-microliter hanging drops.
Methods in enzymology 1986;121():327-31.
1985: M Brown; Mary P Stenzel-Poore; Marvin B Rittenberg
Immunologic memory to phosphocholine. VII. Lack of T15 V1 gene utilization in Xid anti-PC hybridomas.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(5):3558-63.
1985: T J Hall; Marvin B Rittenberg
A novel in vitro assay for mouse IgE.
Journal of immunological methods 1985;80(2):145-54.
1985: I Todd; M Brown; Marvin B Rittenberg
Immunologic memory to phosphorylcholine. VI. Heterogeneity in light chain gene expression.
European journal of immunology 1985;15(2):177-83.
1984: B Golding; Marvin B Rittenberg
Human thymus-independent antibody response in vitro: III. Precursor frequencies and fine specificity of human B cells stimulated by TNP-Ba in the presence and absence of Con A.
Cellular immunology 1984;85(2):309-17.
1984: M Brown; G Schiffman; Marvin B Rittenberg
Subpopulations of antibodies to phosphocholine in human serum.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(3):1323-8.
1984: I Todd; S P Chang; R M Perlmutter; R Aebersold; C H Heusser; L Hood; Marvin B Rittenberg
Immunologic memory to phosphocholine. V. Hybridomas representative of group II antibodies utilize V kappa 1-3 gene(s).
Journal of immunology (Baltimore, Md. : 1950) 1984;132(3):1556-60.
1984: S P Chang; R M Perlmutter; M Brown; C H Heusser; L Hood; Marvin B Rittenberg
Immunologic memory to phosphocholine. IV. Hybridomas representative of Group I (T15-like) and Group II (non-T15-like) antibodies utilize distinct VH genes.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(3):1550-5.
1983: E B Bell; M Brown; Marvin B Rittenberg
In vitro antibody synthesis in 20 microliters hanging drops: initiation of secondary responses and a simple method of cloning hybridomas.
Journal of immunological methods 1983;62(2):137-45.
1982: Hana Golding; P G Foiles; Marvin B Rittenberg
Partial reconstitution of TNP-Ficoll responses and IgG3 expression in Xid mice undergoing graft-vs-host reaction.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(6):2641-6.
1982: Hana Golding; Marvin B Rittenberg
In vivo allogeneic effects: shift in the isotype profile of primary TI-2 responses in mice undergoing graft-vs-host reaction.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(5):1878-82.
1982: S P Chang; M Brown; Marvin B Rittenberg
Immunologic memory to phosphorylcholine III. IgM includes a fine specificity population distinct from TEPC 15.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(4):1559-62.
1982: B Golding; D R Burger; Marvin B Rittenberg
Lectin-induced regulation of human thymus-independent anti-TNP responses in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(3):942-5.
1982: Hana Golding; Marvin B Rittenberg
In vitro and in vivo allogeneic effects: differential modulation of B cell subpopulations.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(4):1625-30.
1982: S P Chang; M Brown; Marvin B Rittenberg
Immunologic memory to phosphorylcholine. II. PC-KLH induces two antibody populations that dominate different isotypes.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(2):702-6.
1982: S L Kaattari; Marvin B Rittenberg
Concanavalin A supernatant recruits antigen-insensitive IgG memory B lymphocyte precursors into an antigen-sensitive precursor pool.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(2):720-5.
1982: M L Cohn; Hana Golding; Marvin B Rittenberg
Antibodies to cell surface antigens detected by a rapid spot test using ethidium bromide.
Journal of immunological methods 1982;49(1):75-82.
1981: B Golding; S P Chang; Hana Golding; Richard Jones; K L Pratt; D R Burger; Marvin B Rittenberg
Human lymphocytes can generate thymus-independent as well as thymus-dependent anti-hapten plaque-forming cell responses in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(1):220-4.
1981: S P Chang; Marvin B Rittenberg
Immunologic memory to phosphorylcholine in vitro. I. Asymmetric expression of clonal dominance.
Journal of immunology (Baltimore, Md. : 1950) 1981;126(3):975-80.
1980: Hana Golding; Marvin B Rittenberg
Differential sensitivity of IgG memory subpopulations to allogeneic thymocytes: positive and negative signals.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(3):1284-90.
1980: T V Tittle; Marvin B Rittenberg
IgG B memory cell subpopulations: differences in susceptibility to stimulation by TI-1 and TI-2 antigens.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(1):202-6.
1979: H Golding; M A Cuchens; G A Leslie; Marvin B Rittenberg
Cross-reactivity of rat, mouse, and human IgD.
Journal of immunology (Baltimore, Md. : 1950) 1979;123(6):2751-5.
1979: J A Black; Marvin B Rittenberg; R H Bigley; R D Koler
Hemolytic anemia due to pyruvate kinase deficiency: characterization of the enzymatic activity from eight patients.
American journal of human genetics 1979;31(3):300-10.
1978: T V Tittle; Marvin B Rittenberg
Distinct subpopulations of IgG memory B cells respond to different molecular forms of the same hapten.
Journal of immunology (Baltimore, Md. : 1950) 1978;121(3):936-41.
1978: J A Black; Marvin B Rittenberg; R J Standerfer; J S Peterson
Hereditary persistence of fetal erythrocyte pyruvate kinase in the Basenji dog.
Progress in clinical and biological research 1978;21():275-95.
1978: T V Tittle; Marvin B Rittenberg
Expression of IgG memory response in vitro to thymus-dependent and thymus-independent antigens.
Cellular immunology 1978;35(1):180-90.
1978: Marvin B Rittenberg; T V Tittle
Independent precursors for thymus dependent and thymus independent IgG memory B cells.
Advances in experimental medicine and biology 1978;98():387-97.
1977: R N Harkins; J A Black; Marvin B Rittenberg
M2 isozyme of pyruvate kinase from human kidney as the product of a separate gene: its purification and characterization.
Biochemistry 1977;16(17):3831-7.
1977: D R Lincoln; Marvin B Rittenberg; J A Black
Immunological cross-reaction between eukaryote and prokaryote pyruvate kinase.
FEBS letters 1977;80(1):145-7.
1977: R N Harkins; J A Black; Marvin B Rittenberg
Purification and characterization of human muscle pyruvate kinase.
Canadian journal of biochemistry 1977;55(4):301-7.
1977: M Baltz; Marvin B Rittenberg
Down regulation in B lymphocytes: low dose signals.
European journal of immunology 1977;7(4):218-22.
1977: M Baltz; Marvin B Rittenberg
Low-dose antigenic signals to helper lymphocytes.
Cellular immunology 1977;28(1):125-32.
1977: J D Gabourel; G H Davies; Marvin B Rittenberg
Effects of salicylate and phenobarbital on lymphocyte proliferation and function.
Clinical immunology and immunopathology 1977;7(1):53-61.
1976: J J Jennings; Marvin B Rittenberg
Evidence for separate subpopulations of B cells responding to T-independent and T-dependent immunogens.
Journal of immunology (Baltimore, Md. : 1950) 1976;117(5 Pt.2):1749-52.
1976: Marvin B Rittenberg; C T Pinney; B H Iglewski
Antigenic relationships on the diphtheria toxin molecule: antitoxin versus antitoxoid.
Infection and immunity 1976;14(1):122-8.
1976: A Roman; Marvin B Rittenberg
Modulation of the expression of a secondary IgG antihapten response in vitro.
Advances in experimental medicine and biology 1976;73 Pt B():41-51.
1975: D R Lincoln; J A Black; Marvin B Rittenberg
The immunological properties of pyruvate kinase. II. The relationship of the human erythrocyte isozyme to the human liver isozymes.
Biochimica et biophysica acta 1975;410(2):279-84.
1975: J J Jennings; M Baltz; Marvin B Rittenberg
In vitro immunogenicity of trinitrophenylated bacteriophage T4. I. Lack of helper cell cooperation.
Journal of immunology (Baltimore, Md. : 1950) 1975;115(5):1432-7.
1975: Marvin B Rittenberg; C J Chern; D R Lincoln; J A Black
The immunological properties of pyruvate kinase. I: Mammalian erythrocyte enzymes.
Immunochemistry 1975;12(6-7):491-4.
1975: R J Standerfer; Marvin B Rittenberg; C J Chern; J W Templeton; J A Black
Canine erythrocyte pyruvate kinase. II. Properties of abnormal enzyme associated with hemolytic anemia in the Basenji dog.
Biochemical genetics 1975;13(5-6):341-51.
1975: J A Black; C J Chern; Marvin B Rittenberg
Canine erythrocyte pyruvate kinase. I. Properties of the normal enzyme.
Biochemical genetics 1975;13(5-6):331-9.
1975: B H Iglewski; Marvin B Rittenberg; W J Iglewski
Preferential inhibition of growth and protein synthesis in Rous sarcoma virus transformed cells by diphtheria toxin.
Virology 1975;65(1):272-5.
1975: R M Gorczynski; Marvin B Rittenberg
Analysis of mixed leucocyte culture (MLC) reactive cells after in vitro priming. Changes in avidity of T cell receptors.
Cellular immunology 1975;16(1):171-81.
1974: M Feldmann; M F Greaves; David Parker; Marvin B Rittenberg
Direct triggering of B lymphocytes by insolubilized antigen.
European journal of immunology 1974;4(9):591-7.
1974: B H Iglewski; Marvin B Rittenberg
Selective toxicity of diphtheria toxin for malignant cells.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(7):2707-10.
1974: R M Gorczynski; Marvin B Rittenberg
Stimulation of early protein synthesis as an assay of immune reactivity: analysis of the cells responding to mitogens and alloantigens.
Journal of immunology (Baltimore, Md. : 1950) 1974;112(1):47-55.
1972: C J Chern; Marvin B Rittenberg; J A Black
Purification of human erythrocyte pyruvate kinase.
The Journal of biological chemistry 1972;247(22):7173-80.
1972: L J Jackson; Marvin B Rittenberg; G V Seaman
On the isolation of materials with Rh antigenic properties from the human erythrocyte membrane.
Clinica chimica acta; international journal of clinical chemistry 1972;39(2):463-5.
1972: Marvin B Rittenberg; W W Bullock
In vitro initiated secondary anti-hapten response. 3. Separable roles of hapten and carrier in immune paralysis.
Immunochemistry 1972;9(5):491-504.
1970: W W Bullock; Marvin B Rittenberg
In vitro-initiated secondary anti-hapten response. II. Increasing cell avidity for antigen.
The Journal of experimental medicine 1970;132(5):926-40.
1970: W W Bullock; Marvin B Rittenberg
Kinetics of in vitro initiated secondary anti-hapten response: induction of plaque-forming cells by soluble and particulate antigen.
Immunochemistry 1970;7(3):310-4.
1969: Marvin B Rittenberg; K L Pratt
Antitrinitrophenyl (TNP) plaque assay. Primary response of Balb/c mice to soluble and particulate immunogen.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1969;132(2):575-81.
1969: P Barber; Marvin B Rittenberg
Anti-trinitrophenyl (TNP) antibody detection by neutralization of TNP-coliphage T4.
Immunochemistry 1969;6(2):163-74.
1968: Marvin B Rittenberg; D H Campbell
Heterologous carriers in the anamnestic antihapten response.
The Journal of experimental medicine 1968;127(4):717-30.
1966: Marvin B Rittenberg; A A Amkraut
Immunogenicity of trinitrophenyl-hemocyanin: production of primary and secondary anti-hapten precipitins.
Journal of immunology (Baltimore, Md. : 1950) 1966;97(3):421-30.
1963: H E WEIMER; Marvin B Rittenberg; E L NELSON
THE SERUM GLYCOPROTEIN RESPONSE FOLLOWING X-IRRADIATION AND PRIMARY IMMUNIZATION IN THE RABBIT.
Canadian journal of biochemistry and physiology 1963;41():2147-56.
1963: Marvin B Rittenberg; E L NELSON
Lengthened induction period or immunologic unresponsiveness depending on antigen dose in adult, X-irradiated rabbits.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1963;113():101-4.
1962: Marvin B Rittenberg; E L NELSON
Maintenance of globulin levels in x-irradiated rabbits after immunization.
Science (New York, N.Y.) 1962;138(3539):519-20.
1960: Marvin B Rittenberg; E L NELSON
Macrophages, nucleic acids, and the induction of antibody formation. A review.
The American naturalist 1960;94():321-42.
1958: Marvin B Rittenberg; W D LINSCOTT; M G BALL
Simple method for separating leptospirae from contaminating microorganisms.
Journal of bacteriology 1958;76(6):669-70.