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Susan Rittling

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Maki Morishita; Noriaki Ono; Kentano Miyai; Tomomi Nakagawa; Ryo Hanyu; M Nagao; Paksinee Kamolratanakul; Takuya Notomi; Susan R Rittling; David T Denhardt; Henry M Kronenberg; Yoichi Ezura; Tadayoshi Hayata; Tetsuya Nakamoto; Masaki Noda
Osteopontin deficiency enhances parathyroid hormone/ parathyroid hormone related peptide receptor (PPR) signaling-induced alteration in tooth formation and odontoblastic morphology.
Susan R Rittling
Osteopontin in macrophage function.
Sadanori Shimizu; Naoki Okuda; Norihiko Kato; Susan R Rittling; Atsushi Okawa; Kenichi Shinomiya; Takeshi Muneta; David T Denhardt; Masaki Noda; Kunikazu Tsuji; Yoshinori Asou
Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages.

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2011: Maki Morishita; Noriaki Ono; Kentano Miyai; Tomomi Nakagawa; Ryo Hanyu; M Nagao; Paksinee Kamolratanakul; Takuya Notomi; Susan R Rittling; David T Denhardt; Henry M Kronenberg; Yoichi Ezura; Tadayoshi Hayata; Tetsuya Nakamoto; Masaki Noda
Osteopontin deficiency enhances parathyroid hormone/ parathyroid hormone related peptide receptor (PPR) signaling-induced alteration in tooth formation and odontoblastic morphology.
Tissue & cell 2011;43(3):196-200.
2011: Susan R Rittling
Osteopontin in macrophage function.
Expert reviews in molecular medicine 2011;13():e15.
2010: Sadanori Shimizu; Naoki Okuda; Norihiko Kato; Susan R Rittling; Atsushi Okawa; Kenichi Shinomiya; Takeshi Muneta; David T Denhardt; Masaki Noda; Kunikazu Tsuji; Yoshinori Asou
Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages.
Arthritis and rheumatism 2010;62(5):1329-37.
2010: Laurent MONFOULET; Luc Malaval; Jane E Aubin; Susan R Rittling; Alain P Gadeau; Jean-Christophe Fricain; Olivier Chassande
Bone sialoprotein, but not osteopontin, deficiency impairs the mineralization of regenerating bone during cortical defect healing.
Bone 2010;46(2):447-52.
2010: Norihito Fujita; Shuko Fujita; Yuka Okada; Kyoko Fujita; Ai Kitano; Osamu Yamanaka; Takeshi Miyamoto; Shigeyuki Kon; Toshimitsu Uede; Susan R Rittling; David T Denhardt; Shizuya Saika
Impaired angiogenic response in the corneas of mice lacking osteopontin.
Investigative ophthalmology & visual science 2010;51(2):790-4.
2010: Susan R Rittling; Craig Zetterberg; Kader Yagiz; Stephen Skinner; Noriyuki Suzuki; Akira Fujimura; Hajime Sasaki
Protective role of osteopontin in endodontic infection.
Immunology 2010;129(1):105-14.
2009: Masatsugu Kurokawa; Satoshi Konno; Ayumu Takahashi; Beverly Plunkett; Susan R Rittling; Yutaka Matsui; Shigeyuki Kon; Junko Morimoto; Toshimitsu Uede; Satoshi Matsukura; Fumio Kokubu; Mitsuru Adachi; Masaharu Nishimura; Shau-Ku Huang
Regulatory role of DC-derived osteopontin in systemic allergen sensitization.
European journal of immunology 2009;39(12):3323-30.
2009: Sukyee Kwok; Susan R Rittling; Nicola C Partridge; Chellakkan S Benson; Mayuranathan Thiyagaraj; Narasimhan Srinivasan; Nagarajan Selvamurugan
Transforming growth factor-beta1 regulation of ATF-3 and identification of ATF-3 target genes in breast cancer cells.
Journal of cellular biochemistry 2009;108(2):408-14.
2009: Kader Yagiz; Susan R Rittling
Both cell-surface and secreted CSF-1 expressed by tumor cells metastatic to bone can contribute to osteoclast activation.
Experimental cell research 2009;315(14):2442-52.
2009: Yoshimasa Maeno; Masanori Shinzato; Shigeo Nagashima; Susan R Rittling; David T Denhardt; Toshimitsu Uede; Koki Taniguchi
Effect of osteopontin on diarrhea duration and innate immunity in suckling mice infected with a murine rotavirus.
Viral immunology 2009;22(2):139-44.
2008: Laetitia Lam Shang Leen; Cédric Filipe; Audrey Billon; Barbara Garmy-Susini; Sandra Jalvy; Fanny Robbesyn; Danièle Daret; Cécile Allières; Susan R Rittling; Nikos Werner; Georg Nickenig; Urban Deutsch; Cécile Duplàa; Pascale Dufourcq; Françoise Lenfant; Claude Desgranges; Jean-François Arnal; Alain-Pierre Gadeau
Estrogen-stimulated endothelial repair requires osteopontin.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(12):2131-6.
2008: Ikuko Sato; Nobuchika Yamamoto; Susan R Rittling; David T Denhardt; Motohiro Hino; Junko Morimoro; Fumihiko Sakai; Akihiko Fujie; Toshimitsu Uede
Osteopontin is dispensable for protection against high load systemic fungal infection.
International immunopharmacology 2008;8(10):1441-8.
2008: Noriaki Ono; Kazuhisa Nakashima; Susan R Rittling; Ernestina Schipani; Tadayoshi Hayata; Kunimichi Soma; David T Denhardt; Henry M Kronenberg; Yoichi Ezura; Masaki Noda
Osteopontin negatively regulates parathyroid hormone receptor signaling in osteoblasts.
The Journal of biological chemistry 2008;283(28):19400-9.
2008: Ken-ichi Miyazaki; Yuka Okada; Osamu Yamanaka; Ai Kitano; Kazuo Ikeda; Shigeyuki Kon; Toshimitsu Uede; Susan R Rittling; David T Denhardt; Winston W-Y Kao; Shizuya Saika
Corneal wound healing in an osteopontin-deficient mouse.
Investigative ophthalmology & visual science 2008;49(4):1367-75.
2008: Chooryung J Chung; Kunimichi Soma; Susan R Rittling; David T Denhardt; Tadayoshi Hayata; Kazuhisa Nakashima; Yoichi Ezura; Masaki Noda
OPN deficiency suppresses appearance of odontoclastic cells and resorption of the tooth root induced by experimental force application.
Journal of cellular physiology 2008;214(3):614-20.
2007: Christian C Kazanecki; Aaron J Kowalski; Tony Ding; Susan R Rittling; David T Denhardt
Characterization of anti-osteopontin monoclonal antibodies: Binding sensitivity to post-translational modifications.
Journal of cellular biochemistry 2007;102(4):925-35.
2007: Bradley Yates; Craig Zetterberg; Vaishali Rajeev; Michael Reiss; Susan R Rittling
Promoter-independent regulation of vimentin expression in mammary epithelial cells by val(12)ras and TGFbeta.
Experimental cell research 2007;313(17):3718-28.
2007: Shashi K Ramaiah; Susan R Rittling
Role of osteopontin in regulating hepatic inflammatory responses and toxic liver injury.
Expert opinion on drug metabolism & toxicology 2007;3(4):519-26.
2007: Brian Christensen; Christian C Kazanecki; Torben E Petersen; Susan R Rittling; David T Denhardt; Esben S Sørensen
Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties.
The Journal of biological chemistry 2007;282(27):19463-72.
2007: Chikako Hayashi; Susan R Rittling; Tadayoshi Hayata; Teruo Amagasa; David T Denhardt; Yoichi Ezura; Kazuhisa Nakashima; Masaki Noda
Serum osteopontin, an enhancer of tumor metastasis to bone, promotes B16 melanoma cell migration.
Journal of cellular biochemistry 2007;101(4):979-86.
2007: Mizuki Kitamura; Kazuya Iwabuchi; Nobuyoshi Kitaichi; Shigeyuki Kon; Hirokuni Kitamei; Kenichi Namba; Kazuhiko Yoshida; David T Denhardt; Susan R Rittling; Shigeaki Ohno; Toshimitsu Uede; Kazunori Onoé
Osteopontin aggravates experimental autoimmune uveoretinitis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6567-72.
2007: Muneaki Ishijima; Kunikazu Tsuji; Susan R Rittling; Teruhito Yamashita; Hisashi Kurosawa; David T Denhardt; Akira Nifuji; Yoichi Ezura; Masaki Noda
Osteopontin is required for mechanical stress-dependent signals to bone marrow cells.
The Journal of endocrinology 2007;193(2):235-43.
2007: Norihiko Kato; Keiichiro Kitahara; Susan R Rittling; Kazuhisa Nakashima; David T Denhardt; Hisashi Kurosawa; Yoichi Ezura; Masaki Noda
Osteopontin deficiency enhances anabolic action of EP4 agonist at a sub-optimal dose in bone.
The Journal of endocrinology 2007;193(1):171-82.
2007: Masayuki Hashimoto; Dongming Sun; Susan R Rittling; David T Denhardt; Wise Young
Osteopontin-deficient mice exhibit less inflammation, greater tissue damage, and impaired locomotor recovery from spinal cord injury compared with wild-type controls.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(13):3603-11.
2007: Shizuya Saika; Kumi Shirai; Osamu Yamanaka; Ken-Ichi Miyazaki; Yuka Okada; Ai Kitano; Kathleen C Flanders; Shigeyuki Kon; Toshimitsu Uede; Winston W-Y Kao; Susan R Rittling; David T Denhardt; Yoshitaka Ohnishi
Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium.
Laboratory investigation; a journal of technical methods and pathology 2007;87(2):130-8.
2007: Noriaki Mori; Tokifumi Majima; Norimasa Iwasaki; Shigeyuki Kon; Kiyoshi Miyakawa; Chiemi Kimura; Kunio Tanaka; David T Denhardt; Susan R Rittling; Akio Minami; Toshimitsu Uede
The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation.
Matrix biology : journal of the International Society for Matrix Biology 2007;26(1):42-53.
2006: Muneaki Ishijima; Yoichi Ezura; Kunikazu Tsuji; Susan R Rittling; Hisashi Kurosawa; David T Denhardt; Mitsuru Emi; Akira Nifuji; Masaki Noda
Osteopontin is associated with nuclear factor kappaB gene expression during tail-suspension-induced bone loss.
Experimental cell research 2006;312(16):3075-83.
2006: Andre Paes Batista Da Silva; Aaron Pollett; Susan R Rittling; David T Denhardt; Jaro Sodek; Ron Zohar
Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death.
Journal of cellular physiology 2006;208(3):629-39.
2006: Rongrong Ge; Vaishali Rajeev; Partha Ray; Edmund Lattime; Susan R Rittling; Satyanarayana Medicherla; Protter Andrew; Alison Murphy; Jit Chakravarty; Sundeep Dugar; George F Schreiner; Nicola Barnard; Michael Reiss
Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-beta type I receptor kinase in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(14 Pt 1):4315-30.
2006: Chung-Fang Lai; Venkat Seshadri; Kane Huang; Jian-Su Shao; Jun Cai; Radhika Vattikuti; Arwyn Schumacher; Arleen P Loewy; David T Denhardt; Susan R Rittling; Dwight A Towler
An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells.
Circulation research 2006;98(12):1479-89.
2006: Yuki Koyama; Susan R Rittling; Kunikazu Tsuji; Kazunori Hino; Ruchanee Salincarnboriboon; Tetsu Yano; Yuji Taketani; Akira Nifuji; David T Denhardt; Masaki Noda
Osteopontin deficiency suppresses high phosphate load-induced bone loss via specific modulation of osteoclasts.
Endocrinology 2006;147(6):3040-9.
2006: Yoshimasa Maeno; Shusuke Nakazawa; Naoki Yamamoto; Masanori Shinzato; Shigeo Nagashima; Kumiko Tanaka; Jun Sasaki; Susan R Rittling; David T Denhardt; Toshimitsu Uede; Koki Taniguchi
Osteopontin participates in Th1-mediated host resistance against nonlethal malaria parasite Plasmodium chabaudi chabaudi infection in mice.
Infection and immunity 2006;74(4):2423-7.
2006: Tajneen Natasha; Misty Kuhn; Owen Kelly; Susan R Rittling
Override of the osteoclast defect in osteopontin-deficient mice by metastatic tumor growth in the bone.
The American journal of pathology 2006;168(2):551-61.
2006: Dionne Lorena; Ian A Darby; Alain-Pierre Gadeau; Laetitia Lam Shang Leen; Susan R Rittling; Luis Cristovao Porto; Jean Rosenbaum; Alexis Desmoulière
Osteopontin expression in normal and fibrotic liver. altered liver healing in osteopontin-deficient mice.
Journal of hepatology 2006;44(2):383-90.
2005: Hilary J Vernon; Christine Osborne; Eleni G Tzortzaki; Min Yang; Jianmen Chen; Susan R Rittling; David T Denhardt; Steven Buyske; Sharon B Bledsoe; Andrew P Evan; Lynette Fairbanks; H Anne Simmonds; Jay A Tischfield; Amrik Sahota
Aprt/Opn double knockout mice: osteopontin is a modifier of kidney stone disease severity.
Kidney international 2005;68(3):938-47.
2005: Hisataka Kondo; Akira Nifuji; Shu Takeda; Yoichi Ezura; Susan R Rittling; David T Denhardt; Kazuhisa Nakashima; Gerard Karsenty; Masaki Noda
Unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system.
The Journal of biological chemistry 2005;280(34):30192-200.
2005: Andrew P Evan; Fredric L Coe; Susan R Rittling; Sharon M Bledsoe; Youzhi Shao; James E Lingeman; Elaine M Worcester
Apatite plaque particles in inner medulla of kidneys of calcium oxalate stone formers: osteopontin localization.
Kidney international 2005;68(1):145-54.
2005: Sebastian Stier; Yon Ko; Randolf Forkert; Christoph Lutz; Thomas Neuhaus; Elisabeth Grünewald; Tao Cheng; David Dombkowski; Laura M Calvi; Susan R Rittling; David T Scadden
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size.
The Journal of experimental medicine 2005;201(11):1781-91.
2005: Tanupriya Contractor; Bruce Babiarz; Aaron J Kowalski; Susan R Rittling; Esben S Sørensen; David T Denhardt
Osteoclasts resorb protein-free mineral (Osteologic discs) efficiently in the absence of osteopontin.
In vivo (Athens, Greece) 2005;19(2):335-41.
2005: Ellen E Rollo; Scott J Hempson; Ajay Bansal; Ernest Tsao; Iman Habib; Susan R Rittling; David T Denhardt; Erich R Mackow; Robert D Shaw
The cytokine osteopontin modulates the severity of rotavirus diarrhea.
Journal of virology 2005;79(6):3509-16.
2005: Misty Kuhn; Sarah Shah; Tajneen Natasha; Susan R Rittling
A mouse model of breast cancer metastasis to the choroid of the eye.
Clinical & experimental metastasis 2005;22(8):685-90.
2004: Hongyan Diao; Shigeyuki Kon; Kazuya Iwabuchi; Chiemi Kimura; Junko Morimoto; Daisuke Ito; Tatsuya Segawa; Masahiro Maeda; Junji Hamuro; Toshinori Nakayama; Masaru Taniguchi; Hideo Yagita; Luc Van Kaer; Kazunori Onóe; David T Denhardt; Susan R Rittling; Toshimitsu Uede
Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases.
Immunity 2004;21(4):539-50.
2004: Yoshio Ohyama; Hiroyuki Nemoto; Susan R Rittling; Kunikazu Tsuji; Teruo Amagasa; David T Denhardt; Akira Nifuji; Masaki Noda
Osteopontin-deficiency suppresses growth of B16 melanoma cells implanted in bone and osteoclastogenesis in co-cultures.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(10):1706-11.
2004: Yutaka Matsui; Nan Jia; Hiroshi Okamoto; Shigeyuki Kon; Hisao Onozuka; Masatoshi Akino; Lizhi Liu; Junko Morimoto; Susan R Rittling; David T Denhardt; Akira Kitabatake; Toshimitsu Uede
Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy.
Hypertension 2004;43(6):1195-201.
2004: Susan R Rittling; A F Chambers
Role of osteopontin in tumour progression.
British journal of cancer 2004;90(10):1877-81.
2004: Junko Morimoto; Manabu Inobe; Chiemi Kimura; Shigeyuki Kon; Hongyan Diao; Momoe Aoki; Tadaaki Miyazaki; David T Denhardt; Susan R Rittling; Toshimitsu Uede
Osteopontin affects the persistence of beta-glucan-induced hepatic granuloma formation and tissue injury through two distinct mechanisms.
International immunology 2004;16(3):477-88.
2004: Brenda Bourassa; Sara Monaghan; Susan R Rittling
Impaired anti-tumor cytotoxicity of macrophages from osteopontin-deficient mice.
Cellular immunology 2004;227(1):1-11.
2004: Baoqian Zhu; Keiko Suzuki; Harvey A Goldberg; Susan R Rittling; David T Denhardt; Christopher A McCulloch; Jaro Sodek
Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: evidence of a role for an intracellular form of osteopontin.
Journal of cellular physiology 2004;198(1):155-67.
2003: Mikihiko Morinobu; Muneaki Ishijima; Susan R Rittling; Kunikazu Tsuji; Haruyasu Yamamoto; Akira Nifuji; David T Denhardt; Masaki Noda
Osteopontin expression in osteoblasts and osteocytes during bone formation under mechanical stress in the calvarial suture in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(9):1706-15.
2003: Meenakshi A Chellaiah; Rajatsubhra Biswas; Susan R Rittling; David T Denhardt; Keith A Hruska
Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts.
The Journal of biological chemistry 2003;278(31):29086-97.
2003: Yutaka Matsui; Susan R Rittling; Hiroshi Okamoto; Manabu Inobe; Nan Jia; Toshihiro Shimizu; Masatoshi Akino; Takeshi Sugawara; Junko Morimoto; Chiemi Kimura; Shigeyuki Kon; David T Denhardt; Akira Kitabatake; Toshimitsu Uede
Osteopontin deficiency attenuates atherosclerosis in female apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(6):1029-34.
2003: Keiichiro Kitahara; Muneaki Ishijima; Susan R Rittling; Kunikazu Tsuji; Hisashi Kurosawa; Akira Nifuji; David T Denhardt; Masaki Noda
Osteopontin deficiency induces parathyroid hormone enhancement of cortical bone formation.
Endocrinology 2003;144(5):2132-40.
2003: Yanping Chen; Susan R Rittling
Novel murine mammary epithelial cell lines that form osteolytic bone metastases: effect of strain background on tumor homing.
Clinical & experimental metastasis 2003;20(2):111-20.
2003: David T Denhardt; Devra Mistretta; Ann F Chambers; Shuba Krishna; Joseph F Porter; Srilatha Raghuram; Susan R Rittling
Transcriptional regulation of osteopontin and the metastatic phenotype: evidence for a Ras-activated enhancer in the human OPN promoter.
Clinical & experimental metastasis 2003;20(1):77-84.
2003: Meenakshi A Chellaiah; N Kizer; Rajatsubhra Biswas; Ulises Alvarez; J Strauss-Schoenberger; Leonard Rifas; Susan R Rittling; David T Denhardt; Keith A Hruska
Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expression.
Molecular biology of the cell 2003;14(1):173-89.
2002: Keiko Suzuki; Baoqian Zhu; Susan R Rittling; David T Denhardt; Harvey A Goldberg; Christopher A McCulloch; Jaro Sodek
Colocalization of intracellular osteopontin with CD44 is associated with migration, cell fusion, and resorption in osteoclasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(8):1486-97.
2002: Kenji Yumoto; Muneaki Ishijima; Susan R Rittling; Kunikazu Tsuji; Yoko Tsuchiya; Shigeyuki Kon; Akira Nifuji; Toshimitsu Uede; David T Denhardt; Masaki Noda
Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4556-61.
2002: Muneaki Ishijima; Kunikazu Tsuji; Susan R Rittling; Teruhito Yamashita; Hisashi Kurosawa; David T Denhardt; Akira Nifuji; Masaki Noda
Resistance to unloading-induced three-dimensional bone loss in osteopontin-deficient mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(4):661-7.
2002: Susan R Rittling; Yanping Chen; Fei Feng; Yiming Wu
Tumor-derived osteopontin is soluble, not matrix associated.
The Journal of biological chemistry 2002;277(11):9175-82.
2002: Melissa R Potter; Susan R Rittling; David T Denhardt; Randall J Roper; John H Weis; Cory Teuscher; Janis J Weis
Role of osteopontin in murine Lyme arthritis and host defense against Borrelia burgdorferi.
Infection and immunity 2002;70(3):1372-81.
2001: H Ihara; David T Denhardt; K Furuya; Tokuyuki Yamashita; Y Muguruma; Kunikazu Tsuji; Keith A Hruska; Kanji Higashio; S Enomoto; Akira Nifuji; Susan R Rittling; Mitsuhiko Noda
Parathyroid hormone-induced bone resorption does not occur in the absence of osteopontin.
The Journal of biological chemistry 2001;276(16):13065-71.
2001: H Nemoto; Susan R Rittling; Hiroyuki Yoshitake; K Furuya; Teruo Amagasa; Kunikazu Tsuji; Akira Nifuji; David T Denhardt; Mitsuhiko Noda
Osteopontin deficiency reduces experimental tumor cell metastasis to bone and soft tissues.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(4):652-9.
2001: Yoshinori Asou; Susan R Rittling; Hiroyuki Yoshitake; Kunikazu Tsuji; Kenichi Shinomiya; Akira Nifuji; David T Denhardt; Mitsuhiko Noda
Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone.
Endocrinology 2001;142(3):1325-32.
2001: Muneaki Ishijima; Susan R Rittling; Tokuyuki Yamashita; Kunikazu Tsuji; Hisashi Kurosawa; Akira Nifuji; David T Denhardt; Mitsuhiko Noda
Enhancement of osteoclastic bone resorption and suppression of osteoblastic bone formation in response to reduced mechanical stress do not occur in the absence of osteopontin.
The Journal of experimental medicine 2001;193(3):399-404.
2001: David T Denhardt; C M Giachelli; Susan R Rittling
Role of osteopontin in cellular signaling and toxicant injury.
Annual review of pharmacology and toxicology 2001;41():723-49.
2000: Fei Feng; Susan R Rittling
Mammary tumor development in MMTV-c-myc/MMTV-v-Ha-ras transgenic mice is unaffected by osteopontin deficiency.
Breast cancer research and treatment 2000;63(1):71-9.
2000: Y Wu; David T Denhardt; Susan R Rittling
Osteopontin is required for full expression of the transformed phenotype by the ras oncogene.
British journal of cancer 2000;83(2):156-63.
1999: Hiroyuki Yoshitake; Susan R Rittling; David T Denhardt; Mitsuhiko Noda
Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):8156-60.
1999: Eisei Noiri; K Dickman; F Miller; G Romanov; V I Romanov; R Shaw; A F Chambers; Susan R Rittling; David T Denhardt; M S Goligorsky
Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene.
Kidney international 1999;56(1):74-82.
1999: Susan R Rittling; David T Denhardt
Osteopontin function in pathology: lessons from osteopontin-deficient mice.
Experimental nephrology 1999;7(2):103-13.
1998: Susan R Rittling; Fei Feng
Detection of mouse osteopontin by western blotting.
Biochemical and biophysical research communications 1998;250(2):287-92.
1998: Susan R Rittling; H N Matsumoto; Marc McKee; A Nanci; X R An; K E Novick; Aaron J Kowalski; M Noda; David T Denhardt
Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(7):1101-11.
1997: Susan R Rittling; K E Novick
Osteopontin expression in mammary gland development and tumorigenesis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(10):1061-9.