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Angel Rivera

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James J Cody; Jason W Ashley; Xu Feng; Gray R Lyons; Sreelatha Meleth; Angel A Rivera; Gene P Siegal; Minghui Wang; Sherry W Yang; Joanne T Douglas
Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model.
María Verónica Lopez; Angel A Rivera; Diego Viale; Minghui Wang; Zeng B Zhu; Ronald D Alvarez; Lorena Benedetti; Alicia I Bravo; Nicasio Cuneo; David T Curiel; Joanne T Douglas; Manuel Gidekel; Kristopher J Kimball; Osvaldo L Podhajcer
A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice.
Sherry W Yang; James J Cody; Angel A Rivera; Reinhard Waehler; Minghui Wang; Kristopher J Kimball; Ronald A Alvarez; Gene P Siegal; Joanne T Douglas; Selvarangan Ponnazhagan
Conditionally replicating adenovirus expressing TIMP2 for ovarian cancer therapy.

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2013: James J Cody; Jason W Ashley; Xu Feng; Gray R Lyons; Sreelatha Meleth; Angel A Rivera; Gene P Siegal; Minghui Wang; Sherry W Yang; Joanne T Douglas
Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model.
Laboratory investigation; a journal of technical methods and pathology 2013;93(3):268-78.
2012: María Verónica Lopez; Angel A Rivera; Diego Viale; Minghui Wang; Zeng B Zhu; Ronald D Alvarez; Lorena Benedetti; Alicia I Bravo; Nicasio Cuneo; David T Curiel; Joanne T Douglas; Manuel Gidekel; Kristopher J Kimball; Osvaldo L Podhajcer
A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(12):2222-33.
2011: Sherry W Yang; James J Cody; Angel A Rivera; Reinhard Waehler; Minghui Wang; Kristopher J Kimball; Ronald A Alvarez; Gene P Siegal; Joanne T Douglas; Selvarangan Ponnazhagan
Conditionally replicating adenovirus expressing TIMP2 for ovarian cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(3):538-49.
2011: Sherry W Yang; Angel A Rivera; Gene P Siegal; Reinhard Waehler; Diptiman Chanda; James J Cody; Joanne T Douglas; Selvarangan Ponnazhagan
Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancer.
PloS one 2011;6(10):e25131.
2010: J J Cody; Angel A Rivera; G R Lyons; S W Yang; Minghui Wang; D B Sarver; D Wang; K S Selander; H-C Kuo; Sreelatha Meleth; Xu Feng; G P Siegal; G P Siegall; Joanne T Douglas
Arming a replicating adenovirus with osteoprotegerin reduces the tumor burden in a murine model of osteolytic bone metastases of breast cancer.
Cancer gene therapy 2010;17(12):893-905.
2010: Joanne T Douglas; Angel A Rivera; Gray R Lyons; Patricia F Lott; Dezhi Wang; Majd zayzafoon; Gene P Siegal; Xu Cao; Steven M Theiss
Ex vivo transfer of the Hoxc-8-interacting domain of Smad1 by a tropism-modified adenoviral vector results in efficient bone formation in a rabbit model of spinal fusion.
Journal of spinal disorders & techniques 2010;23(1):63-73.
2009: Kristopher J Kimball; Angel A Rivera; Kurt R Zinn; Mert Icyuz; Vaibhav Saini; Jing Li; Zeng B Zhu; Gene P Siegal; Joanne T Douglas; David T Curiel; Ronald D Alvarez; Anton V Borovjagin
Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer.
Molecular imaging 2009;8(5):264-77.
2009: Alexander Stoff; Angel A Rivera; N Sanjib Banerjee; Steven T Moore; T Michael Numnum; Antonio Espinosa-de-los-Monteros; Dirk F Richter; Gene P Siegal; Louise T Chow; Dale Feldman; Luis O Vasconez; J Michael Mathis; Mariam A Stoff-Khalili; David T Curiel
Promotion of incisional wound repair by human mesenchymal stem cell transplantation.
Experimental dermatology 2009;18(4):362-9.
2008: Ilya V Ulasov; Matthew A Tyler; Angel A Rivera; Dirk M Nettlebeck; Joanne T Douglas; Lesniak Maciej
Evaluation of E1A double mutant oncolytic adenovectors in anti-glioma gene therapy.
Journal of medical virology 2008;80(9):1595-603.
2008: Adam M Sonabend; Ilya V Ulasov; Matthew A Tyler; Angel A Rivera; J Michael Mathis; Lesniak Maciej
Mesenchymal stem cells effectively deliver an oncolytic adenovirus to intracranial glioma.
Stem cells (Dayton, Ohio) 2008;26(3):831-41.
2008: Mariam A Stoff-Khalili; Angel A Rivera; Ana Nedeljkovic-Kurepa; Arrigo DeBenedetti; Xiao-Lin Li; Yoshinobu Odaka; Jagat Podduturi; Don Arthur Sibley; Gene P Siegal; Alexander Stoff; Scott Young; Zeng B Zhu; David T Curiel; J Michael Mathis
Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control.
Breast cancer research and treatment 2008;108(1):43-55.
2008: Qiana L Matthews; Pingar Yang; Qi Wu; Natalya Belousova; Angel A Rivera; Mariam A Stoff-Khalili; Reinhard Waehler; Hui-Chen Hsu; Zan Li; Jing Li; John D Mountz; Hongju Wu; David T Curiel
Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach.
Virology journal 2008;5():98.
2007: Zeng B Zhu; J Michael Mathis; Sharmila K Makhija; Baogen Lu; Minghui Wang; Shaonin Ji; Angel A Rivera; Eben Rosenthal; Gene P Siegal; David T Curiel
Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck.
International journal of oncology 2007;31(5):1213-22.
2007: Ilya V Ulasov; Angel A Rivera; Dirk M Nettelbeck; Lisa B Rivera; J Michael Mathis; Adam M Sonabend; Matthew Tyler; Ming Wang; Joanne T Douglas; Lesniak Maciej
An oncolytic adenoviral vector carrying the tyrosinase promoter for glioma gene therapy.
International journal of oncology 2007;31(5):1177-85.
2007: Mariam A Stoff-Khalili; Angel A Rivera; J Michael Mathis; nirupama banerjee; Amanda S Moon; A Hess; Rodney P Rocconi; T Michael Numnum; Maaike Everts; Louise T Chow; Joanne T Douglas; Gene P Siegal; Zeng B Zhu; Hans Georg Bender; Peter Dall; Alexander Stoff; Larisa Pereboeva; David T Curiel
Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma.
Breast cancer research and treatment 2007;105(2):157-67.
2007: Ilya V Ulasov; Angel A Rivera; Yu Han; David T Curiel; Zeng B Zhu; Lesniak Maciej
Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells.
Journal of neurosurgery 2007;107(3):617-27.
2007: Ilya V Ulasov; Zeng B Zhu; Matthew A Tyler; Yu Han; Angel A Rivera; Andrey Khramtsov; David T Curiel; Lesniak Maciej
Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma.
Human gene therapy 2007;18(7):589-602.
2007: Ilya V Ulasov; Angel A Rivera; Adam M Sonabend; Lisa B Rivera; Ming Wang; Zeng B Zhu; Lesniak Maciej
Comparative evaluation of survivin, midkine and CXCR4 promoters for transcriptional targeting of glioma gene therapy.
Cancer biology & therapy 2007;6(5):679-85.
2007: Alexander Stoff; Angel A Rivera; J Michael Mathis; Steven T Moore; nirupama banerjee; Maaike Everts; Antonio Espinosa-de-los-Monteros; Zdenek Novak; Luis O Vasconez; Thomas R Broker; Dirk F Richter; Dale Feldman; Gene P Siegal; Mariam A Stoff-Khalili; David T Curiel
Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds.
Journal of molecular medicine (Berlin, Germany) 2007;85(5):481-96.
2007: Rodney P Rocconi; Zeng B Zhu; Mariam A Stoff-Khalili; Angel A Rivera; Baogen Lu; Minghui Wang; Ronald D Alvarez; David T Curiel; Sharmila K Makhija
Treatment of ovarian cancer with a novel dual targeted conditionally replicative adenovirus (CRAd).
Gynecologic oncology 2007;105(1):113-21.
2007: Mariam A Stoff-Khalili; Angel A Rivera; Alexander Stoff; J Michael Mathis; Rodney P Rocconi; Qiana L Matthews; Michael T Numnum; Isabell Herrmann; Peter Dall; Devin E Eckhoff; Joanne T Douglas; Gene P Siegal; Zeng B Zhu; David T Curiel
Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer.
International journal of cancer. Journal international du cancer 2007;120(4):935-41.
2007: Zeng B Zhu; Angel A Rivera; Sharmila K Makhija; Baogen Lu; Minghui Wang; Miiru Izumi; Robert James Cerfolio; Mariam A Stoff-Khalili; Fen Zhou; Koichi Takayama; Gene P Siegal; David T Curiel
Targeting lung cancer using an infectivity enhanced CXCR4-CRAd.
Lung cancer (Amsterdam, Netherlands) 2007;55(2):145-56.
2006: Myung-hee Kim; Thomas M Bodenstine; Lucretia A Sumerel; Angel A Rivera; Andrew H Baker; Joanne T Douglas
Tissue inhibitor of metalloproteinases-2 improves antitumor efficacy of a replicating adenovirus in vivo.
Cancer biology & therapy 2006;5(12):1647-53.
2006: Rodney P Rocconi; Michael T Numnum; Zeng B Zhu; Baogen Lu; Minghui Wang; Angel A Rivera; Mariam A Stoff-Khalili; Ronald D Alvarez; David T Curiel; Sharmila K Makhija
Icodextrin enhances survival in an intraperitoneal ovarian cancer murine model utilizing gene therapy.
Gynecologic oncology 2006;103(3):985-9.
2006: Zeng B Zhu; Yabing Chen; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Masato Yamamoto; shuyi wang; Gene P Siegal; David T Curiel; Jay M McDonald
Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma.
International journal of oncology 2006;29(5):1319-29.
2006: Alexander Stoff; Angel A Rivera; nirupama banerjee; J Michael Mathis; Antonio Espinosa-de-los-Monteros; Long P Le; Jorge I de la Torre; Luis O Vasconez; Thomas R Broker; Dirk F Richter; Mariam A Stoff-Khalili; David T Curiel
Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006;14(5):608-17.
2006: Mariam A Stoff-Khalili; Angel A Rivera; Long P Le; Alexander Stoff; Maaike Everts; Juan L Contreras; D Chen; L Teng; Marianne G Rots; Hidde J Haisma; Rodney P Rocconi; Gerd J Bauerschmitz; Daniel T Rein; Masato Yamamoto; Gene P Siegal; Peter Dall; J Michael Mathis; David T Curiel
Employment of liver tissue slice analysis to assay hepatotoxicity linked to replicative and nonreplicative adenoviral agents.
Cancer gene therapy 2006;13(6):606-18.
2006: Winan J van Houdt; Yosef S Haviv; Baogen Lu; Minghui Wang; Angel A Rivera; Ilya V Ulasov; Martine L M Lamfers; Daniel T Rein; Lesniak Maciej; Gene P Siegal; Clemens M F Dirven; David T Curiel; Zeng B Zhu
The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma.
Journal of neurosurgery 2006;104(4):583-92.
2006: Long P Le; Angel A Rivera; Joel N Glasgow; Vladimir V Ternovoi; Hongju Wu; Minghui Wang; Bruce F Smith; Gene P Siegal; David T Curiel
Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells.
Gene therapy 2006;13(5):389-99.
2005: Mariam A Stoff-Khalili; Angel A Rivera; Joel N Glasgow; Long P Le; Alexander Stoff; Maaike Everts; Yuko Tsuruta; Yosuke Kawakami; Gerd J Bauerschmitz; J Michael Mathis; Larisa Pereboeva; G P Seigal; Peter Dall; David T Curiel
A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy.
Gene therapy 2005;12(23):1696-706.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; J Michael Mathis; Maaike Everts; Minghui Wang; Yosuke Kawakami; Reinhard Waehler; Quiana L Mathews; Masato Yamamoto; Rodney P Rocconi; Gene P Siegal; Dirk F Richter; Peter Dall; Zeng B Zhu; David T Curiel
Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system.
Cancer biology & therapy 2005;4(11):1203-10.
2005: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; SangAe Kim-Park; Ilya V Ulasov; Fen Zhou; Ronald D Alvarez; Gene P Siegal; David T Curiel
Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo.
International journal of oncology 2005;27(1):237-46.
2005: Baogen Lu; Sharmila K Makhija; Dirk M Nettelbeck; Angel A Rivera; Minghui Wang; Svetlana Komarova; Fen Zhou; Masato Yamamoto; Hidde J Haisma; Ronald D Alvarez; David T Curiel; Zeng B Zhu
Evaluation of tumor-specific promoter activities in melanoma.
Gene therapy 2005;12(4):330-8.
2005: Andrea L Volk; Angel A Rivera; Grier P Page; Jesus F Salazar-Gonzalez; Dirk M Nettelbeck; Qiana L Matthews; David T Curiel
Employment of microarray analysis to characterize biologic differences associated with tropism-modified adenoviral vectors: utilization of non-native cellular entry pathways.
Cancer gene therapy 2005;12(2):162-74.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; nirupama banerjee; Maaike Everts; Scott Young; Gene P Siegal; Dirk F Richter; Minghui Wang; Peter Dall; J Michael Mathis; Zeng B Zhu; David T Curiel
Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system.
Breast cancer research : BCR 2005;7(6):R1141-52.
2004: Angel A Rivera; Julia Davydova; S Schierer; Minghui Wang; Victor Krasnykh; Masato Yamamoto; David T Curiel; Dirk M Nettelbeck
Combining high selectivity of replication with fiber chimerism for effective adenoviral oncolysis of CAR-negative melanoma cells.
Gene therapy 2004;11(23):1694-702.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Meredith Preuss; Fen Zhou; Gene P Siegal; Ronald D Alvarez; David T Curiel
Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis.
Virology 2004;325(1):116-28.
2004: nirupama banerjee; Angel A Rivera; Minghui Wang; Louise T Chow; Thomas R Broker; David T Curiel; Dirk M Nettelbeck
Analyses of melanoma-targeted oncolytic adenoviruses with tyrosinase enhancer/promoter-driven E1A, E4, or both in submerged cells and organotypic cultures.
Molecular cancer therapeutics 2004;3(4):437-49.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Lyudmila N Kaliberova; Bin Liu; Angel A Rivera; Dirk M Nettelbeck; Parameshwar J Mahasreshti; Charles A Leath; Masato Yamamoto; M Yamaoto; Ronald D Alvarez; David T Curiel
Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter.
Gene therapy 2004;11(7):645-8.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Lyudmila N Kaliberova; Bin Liu; Angel A Rivera; Dirk M Nettelbeck; Parameshwar J Mahasreshti; Charles A Leath; Shannon Barker; Masato Yamaoto; Fengzhi Li; Ronald D Alvarez; David T Curiel
Transcriptional targeting of tumors with a novel tumor-specific survivin promoter.
Cancer gene therapy 2004;11(4):256-62.
2004: Angel A Rivera; Minghui Wang; Kaori Suzuki; taco uil; Victor Krasnykh; David T Curiel; Dirk M Nettelbeck
Mode of transgene expression after fusion to early or late viral genes of a conditionally replicating adenovirus via an optimized internal ribosome entry site in vitro and in vivo.
Virology 2004;320(1):121-34.
2004: Dirk M Nettelbeck; Angel A Rivera; Jörg Kupsch; Detlef Dieckmann; Joanne T Douglas; Roland Kontermann; Ramon Alemany; David T Curiel
Retargeting of adenoviral infection to melanoma: combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA.
International journal of cancer. Journal international du cancer 2004;108(1):136-45.
2003: Andrea L Volk; Angel A Rivera; Anna Kanerva; Gerd J Bauerschmitz; Igor Dmitriev; Dirk M Nettelbeck; David T Curiel
Enhanced adenovirus infection of melanoma cells by fiber-modification: incorporation of RGD peptide or Ad5/3 chimerism.
Cancer biology & therapy 2003;2(5):511-5.
2003: Shannon D Barker; Igor Dmitriev; Dirk M Nettelbeck; Bin Liu; Angel A Rivera; Ronald D Alvarez; David T Curiel; Akseli Hemminki
Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma.
Gene therapy 2003;10(14):1198-204.
2003: Dirk M Nettelbeck; Angel A Rivera; Julia Davydova; D Dieckmann; Masato Yamamoto; David T Curiel
Cyclooxygenase-2 promoter for tumour-specific targeting of adenoviral vectors to melanoma.
Melanoma research 2003;13(3):287-92.
2003: Shannon D Barker; Candace J Coolidge; Anna Kanerva; Tanja Hakkarainen; Masato Yamamoto; Bin Liu; Angel A Rivera; Snehal M Bhoola; Mack N Barnes; Ronald D Alvarez; David T Curiel; Akseli Hemminki
The secretory leukoprotease inhibitor (SLPI) promoter for ovarian cancer gene therapy.
The journal of gene medicine 2003;5(4):300-10.
2002: Dirk M Nettelbeck; Angel A Rivera; Cristina Balagué; Ramon Alemany; David T Curiel
Novel oncolytic adenoviruses targeted to melanoma: specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter.
Cancer research 2002;62(16):4663-70.