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Pierre Rizkallah

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Julia Ekeruche-Makinde; Sian Llewellyn-Lacey; John J Miles; Kim M Miles; Mark Peakman; Johanne M Pentier; David A Price; Pierre J Rizkallah; Jamie Rossjohn; Andrea J A Schauenburg; Andrew K Sewell; Ania Skowera; Mai Ping Tan; Andrew Trimby; Hugo A van den Berg; Tamsin Williams; Mick Bailey; Anna M Bulek; Scott R Burrows; Mathew Clement; david cole; Garry Dolton; Linda Wooldridge
Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Julia Ekeruche-Makinde; Anna Fuller; Emma Gostick; Kristin Ladell; Anna Lissina; Katy A Lloyd; Florian Madura; Katherine K Matthews; John J Miles; Johanne Pentier; David A Price; Pierre J Rizkallah; Brian M Baker; Tiffany K Baxter; Mathew Clement; david cole; Garry M Dolton; Emily S J Edwards; Linda Wooldridge; Andrew K Sewell
T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting.
Anna M Bulek; Anna Fuller; Christopher J Holland; Florian Madura; Pierre J Rizkallah; Andrea J A Schauenburg; Andrew K Sewell; david cole
TCR/pMHC Optimized Protein crystallization Screen.

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All Publications

2013: Julia Ekeruche-Makinde; Sian Llewellyn-Lacey; John J Miles; Kim M Miles; Mark Peakman; Johanne M Pentier; David A Price; Pierre J Rizkallah; Jamie Rossjohn; Andrea J A Schauenburg; Andrew K Sewell; Ania Skowera; Mai Ping Tan; Andrew Trimby; Hugo A van den Berg; Tamsin Williams; Mick Bailey; Anna M Bulek; Scott R Burrows; Mathew Clement; david cole; Garry Dolton; Linda Wooldridge
Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood 2013;121(7):1112-23.
2012: Julia Ekeruche-Makinde; Anna Fuller; Emma Gostick; Kristin Ladell; Anna Lissina; Katy A Lloyd; Florian Madura; Katherine K Matthews; John J Miles; Johanne Pentier; David A Price; Pierre J Rizkallah; Brian M Baker; Tiffany K Baxter; Mathew Clement; david cole; Garry M Dolton; Emily S J Edwards; Linda Wooldridge; Andrew K Sewell
T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting.
The Journal of biological chemistry 2012;287(44):37269-81.
2012: Anna M Bulek; Anna Fuller; Christopher J Holland; Florian Madura; Pierre J Rizkallah; Andrea J A Schauenburg; Andrew K Sewell; david cole
TCR/pMHC Optimized Protein crystallization Screen.
Journal of immunological methods 2012;382(1-2):203-10.
2012: Sihai Yang; K Mark Thomas; Mikhail Suyetin; Chiu C Tang; David R Allan; Elena Bichoutskaia; Alexander J Blake; Neil R Champness; Peter Hubberstey; William Lewis; Xiang Lin; Julia E Parker; Pierre J Rizkallah; Martin Schröder
A partially interpenetrated metal-organic framework for selective hysteretic sorption of carbon dioxide.
Nature materials 2012;11(8):710-6.
2012: Anna M Bulek; david cole; Garry Dolton; Jan W Drijfhout; Anna Fuller; Emma Gostick; Stephanie Gras; Guo C Huang; Bent K Jakobsen; Robin R Knight; Nikolai M Lissin; Florian Madura; John J Miles; Peter E Molloy; Mark Peakman; David A Price; Pierre J Rizkallah; Jamie Rossjohn; Ania Skowera; Linda Wooldridge; Andrew K Sewell
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nature immunology 2012;13(3):283-9.
2012: Christopher J Holland; Florian Madura; Pierre J Rizkallah; Andrew K Sewell; Lawrence J Stern; Sabrina Vollers; J Mauricio Calvo-Calle; Anna Fuller; Andrew Godkin; David K Cole
Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers.
Scientific reports 2012;2():629.
2011: Stephen W Lane; Caitriona A Dennis; Claire L Lane; Pierre J Rizkallah; Peter G Stockley; Chi H Trinh; Simon E V Phillips
Construction and crystal structure of recombinant STNV capsids.
Journal of molecular biology 2011;413(1):41-50.
2011: Ilich A Ibarra; Xiang Lin; Harriott Nowell; Pierre J Rizkallah; David R Allan; Alexander J Blake; Neil R Champness; Peter Hubberstey; Sihai Yang; Martin Schröder
Highly porous and robust scandium-based metal-organic frameworks for hydrogen storage.
Chemical communications (Cambridge, England) 2011;47(29):8304-6.
2010: Tanya K Ronson; Christopher Carruthers; Julie Fisher; Thierry Brotin; Lindsay P Harding; Pierre J Rizkallah; Michaele J Hardie
Tripodal 4-pyridyl-derived host ligands and their metallo-supramolecular chemistry: stella octangula and bowl-shaped assemblies.
Inorganic chemistry 2010;49(2):675-85.
2010: John J Miles; Anna M Bulek; David K Cole; Emma Gostick; Andrea J A Schauenburg; Garry Dolton; Vanessa Venturi; Miles P Davenport; Mai Ping Tan; Scott R Burrows; Linda Wooldridge; David A Price; Pierre J Rizkallah; Andrew K Sewell
Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.
PLoS pathogens 2010;6(11):e1001198.
2009: david cole; Fang Yuan; Pierre J Rizkallah; John J Miles; Emma Gostick; David A Price; George F Gao; Bent K Jakobsen; Andrew K Sewell
Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.
The Journal of biological chemistry 2009;284(40):27281-9.
2009: Tanya K Ronson; Julie Fisher; Lindsay P Harding; Pierre J Rizkallah; John E Warren; Michaele J Hardie
Stellated polyhedral assembly of a topologically complicated Pd4L4 'Solomon cube'.
Nature chemistry 2009;1(3):212-6.
2008: Lata Govada; Liz Carpenter; Paula C A da Fonseca; John R Helliwell; Pierre J Rizkallah; Emily Flashman; Naomi E Chayen; Charles Redwood; John M Squire
Crystal structure of the C1 domain of cardiac myosin binding protein-C: implications for hypertrophic cardiomyopathy.
Journal of molecular biology 2008;378(2):387-97.
2008: Aleema Westcott; Julie Fisher; Lindsay P Harding; Pierre J Rizkallah; Michaele J Hardie
Self-assembly of a 3-D triply interlocked chiral [2]catenane.
Journal of the American Chemical Society 2008;130(10):2950-1.
2007: Fang Yuan; Theonie Georgiou; Theresa Hillon; Emma Gostick; David A Price; Andrew K Sewell; Ruth Moysey; Jessie Gavarret; Annelise Vuidepot; malkit sami; John I Bell; George F Gao; Pierre J Rizkallah; Bent K Jakobsen
Crystallization and preliminary X-ray structural studies of a Melan-A pMHC-TCR complex.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 9):758-60.
2007: malkit sami; Pierre J Rizkallah; Steve Dunn; Peter Molloy; Ruth Moysey; Annelise Vuidepot; Emma Baston; Penio T Todorov; Yi Li; Feng Gao; Jonathan M Boulter; Bent K Jakobsen
Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry.
Protein engineering, design & selection : PEDS 2007;20(8):397-403.
2007: david cole; Pierre J Rizkallah; Jonathan M Boulter; malkit sami; Annelise Vuidepot; Meir Glick; Feng Gao; John I Bell; Bent K Jakobsen; George F Gao
Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor.
Proteins 2007;67(1):65-74.
2006: Steven M Dunn; Pierre J Rizkallah; Emma Baston; Tara Mahon; Brian Cameron; Ruth Moysey; Feng Gao; malkit sami; Jonathan M Boulter; Yi Li; Bent K Jakobsen
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein science : a publication of the Protein Society 2006;15(4):710-21.
2006: Podjana Chumkhunthod; Sureelak Rodtong; Stanley J Lambert; Anthony P Fordham-Skelton; Pierre J Rizkallah; Mark C Wilkinson; Colin D Reynolds
Purification and characterization of an N-acetyl-D-galactosamine-specific lectin from the edible mushroom Schizophyllum commune.
Biochimica et biophysica acta 2006;1760(3):326-32.
2006: david cole; Pierre J Rizkallah; Feng Gao; Neil I Watson; Jonathan M Boulter; John I Bell; malkit sami; George F Gao; Bent K Jakobsen
Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
European journal of immunology 2006;36(1):170-9.
2005: Ji-Li Chen; Guillaume Stewart-Jones; Giovanna Bossi; Nikolai M Lissin; Linda Wooldridge; Ed Man-Lik Choi; Gerhard Held; P Rod Dunbar; Robert M Esnouf; malkit sami; Jonathan M Boulter; Pierre J Rizkallah; Christoph Renner; Andrew Sewell; Philip van der Merwe; Bent K Jakobsen; Gillian Griffiths; E Yvonne Jones; Vincenzo Cerundolo
Structural and kinetic basis for heightened immunogenicity of T cell vaccines.
The Journal of experimental medicine 2005;201(8):1243-55.
2005: david cole; Pierre J Rizkallah; malkit sami; Nikolai M Lissin; Feng Gao; John I Bell; Jonathan M Boulter; Meir Glick; Annelise Vuidepot; Bent K Jakobsen; George F Gao
Crystallization and preliminary X-ray structural studies of a high-affinity CD8alphaalpha co-receptor to pMHC.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 3):285-7.
2004: Matthew Paul Blakeley; Michele Cianci; John R Helliwell; Pierre J Rizkallah
Synchrotron and neutron techniques in biological crystallography.
Chemical Society reviews 2004;33(8):548-57.
2004: Jarjis Habash; John R Helliwell; James Raftery; Michele Cianci; Pierre J Rizkallah; Naomi E Chayen; Gwen A Nneji; Peter F Zagalsky
The structure and refinement of apocrustacyanin C2 to 1.3 A resolution and the search for differences between this protein and the homologous apoproteins A1 and C1.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 3):493-8.
2003: Naomi E Chayen; Michele Cianci; J Günter Grossmann; Jarjis Habash; John R Helliwell; Gwen A Nneji; James Raftery; Pierre J Rizkallah; Peter F Zagalsky
Unravelling the structural chemistry of the colouration mechanism in lobster shell.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2072-82.
2003: Jonathan M Boulter; Meir Glick; Penio T Todorov; Emma Baston; malkit sami; Pierre J Rizkallah; Bent K Jakobsen
Stable, soluble T-cell receptor molecules for crystallization and therapeutics.
Protein engineering 2003;16(9):707-11.
2003: Annette K Shrive; Hazel A Tharia; Peter Strong; Uday Kishore; Ian Burns; Pierre J Rizkallah; Kenneth B M Reid; Trevor J Greenhough
High-resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D.
Journal of molecular biology 2003;331(2):509-23.
2003: Andrzej Olczak; Michele Cianci; Quan Hao; Pierre J Rizkallah; James Raftery; John R Helliwell
S-SWAT (softer single-wavelength anomalous technique): potential in high-throughput protein crystallography.
Acta crystallographica. Section A, Foundations of crystallography 2003;59(Pt 4):327-34.
2003: Jon Nield; Pierre J Rizkallah; James Barber; Naomi E Chayen
The 1.45 A three-dimensional structure of C-phycocyanin from the thermophilic cyanobacterium Synechococcus elongatus.
Journal of structural biology 2003;141(2):149-55.
2002: Michele Cianci; Pierre J Rizkallah; Andrzej Olczak; James Raftery; Naomi E Chayen; Peter F Zagalsky; John R Helliwell
The molecular basis of the coloration mechanism in lobster shell: beta-crustacyanin at 3.2-A resolution.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):9795-800.
2001: Michele Cianci; Pierre J Rizkallah; Andrzej Olczak; James Raftery; Naomi E Chayen; Peter F Zagalsky; John R Helliwell
Structure of lobster apocrustacyanin A1 using softer X-rays.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 9):1219-29.
2000: Naomi E Chayen; Michele Cianci; Andrzej Olczak; James Raftery; Pierre J Rizkallah; Peter F Zagalsky; John R Helliwell
Apocrustacyanin A1 from the lobster carotenoprotein alpha-crustacyanin: crystallization and initial X-ray analysis involving softer X-rays.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 8):1064-6.
2000: LM Wright; Colin D Reynolds; Pierre J Rizkallah; AK Allen; Els J M Van Damme; MJ Donovan; Willy J Peumans
Structural characterisation of the native fetuin-binding protein Scilla campanulata agglutinin: a novel two-domain lectin.
FEBS letters 2000;468(1):19-22.
1999: M K Sauerborn; LM Wright; Colin D Reynolds; J Günter Grossmann; Pierre J Rizkallah
Insights into carbohydrate recognition by Narcissus pseudonarcissus lectin: the crystal structure at 2 A resolution in complex with alpha1-3 mannobiose.
Journal of molecular biology 1999;290(1):185-99.
1999: SD Wood; LM Wright; Colin D Reynolds; Pierre J Rizkallah; AK Allen; Willy J Peumans; Els J M Van Damme
Structure of the native (unligated) mannose-specific bulb lectin from Scilla campanulata (bluebell) at 1.7 A resolution.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 7):1264-72.
1998: LM Wright; Pierre J Rizkallah; SD Wood; Colin D Reynolds
Scilla campanulata agglutinin crystallized in complex with the trimannoside alpha-D-man-(1-->6)-[alpha-D-man-(1-->3)]-alpha-D-Man.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 4):665-7.
1998: LM Wright; SD Wood; Colin D Reynolds; Pierre J Rizkallah; AK Allen
Crystallization and preliminary structural studies of Scilla campanulata lectin complexed with alpha1-6 mannobiose.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 1):90-2.
1997: LM Wright; SD Wood; Colin D Reynolds; Pierre J Rizkallah; Els J M Van Damme; Willy J Peumans
Crystallization and preliminary X-ray analysis of a novel plant lectin from Calystegia sepium.
Acta crystallographica. Section D, Biological crystallography 1997;53(Pt 2):220-1.
1996: chantalat laurent; SD Wood; Pierre J Rizkallah; Colin D Reynolds
X-ray structure solution of amaryllis lectin by molecular replacement with only 4% of the total diffracting matter.
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 6):1146-52.
1996: LM Wright; SD Wood; Colin D Reynolds; Pierre J Rizkallah; Willy J Peumans; Els J M Van Damme; AK Allen
Purification, crystallization and preliminary X-ray analysis of a mannose-binding lectin from bluebell (Scilla campanulata) bulbs.
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 5):1021-3.
1994: SD Wood; Colin D Reynolds; S Lambert; P A McMichael; AK Allen; Pierre J Rizkallah
Crystallization and preliminary X-ray studies on the mannose-specific lectin from Amaryllis bulbs.
Acta crystallographica. Section D, Biological crystallography 1994;50(Pt 1):110-1.