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Christina Roark

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Christina L Roark; Deming Sun; M Kemal Aydintug; Willi K Born; Tamara Casper; Yafei Huang; Niyun Jin; Rebecca L O'Brien
A canonical Vγ4Vδ4+ γδ T cell population with distinct stimulation requirements which promotes the Th17 response.
Philip L Simonian; Fabian Wehrmann; Christina L Roark; Willi K Born; Rebecca L O'Brien; Andrew P Fontenot
γδ T cells protect against lung fibrosis via IL-22.
Philip L Simonian; Christina L Roark; Willi K Born; Rebecca L O'Brien; Andrew P Fontenot
Gammadelta T cells and Th17 cytokines in hypersensitivity pneumonitis and lung fibrosis.

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All Publications

2013: Christina L Roark; Deming Sun; M Kemal Aydintug; Willi K Born; Tamara Casper; Yafei Huang; Niyun Jin; Rebecca L O'Brien
A canonical Vγ4Vδ4+ γδ T cell population with distinct stimulation requirements which promotes the Th17 response.
Immunologic research 2013;55(1-3):217-30.
2010: Philip L Simonian; Fabian Wehrmann; Christina L Roark; Willi K Born; Rebecca L O'Brien; Andrew P Fontenot
γδ T cells protect against lung fibrosis via IL-22.
The Journal of experimental medicine 2010;207(10):2239-53.
2009: Philip L Simonian; Christina L Roark; Willi K Born; Rebecca L O'Brien; Andrew P Fontenot
Gammadelta T cells and Th17 cytokines in hypersensitivity pneumonitis and lung fibrosis.
Translational research : the journal of laboratory and clinical medicine 2009;154(5):222-7.
2009: Yafei Huang; Niyun Jin; Christina L Roark; M Kemal Aydintug; JM Wands; Hua Huang; Rebecca L O'Brien; Willi K Born
The influence of IgE-enhancing and IgE-suppressive gammadelta T cells changes with exposure to inhaled ovalbumin.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):849-55.
2009: Rebecca L O'Brien; Molly A Taylor; Jacqueline Hartley; Tanja Nuhsbaum; Steve Dugan; Kevin Lahmers; M Kemal Aydintug; JM Wands; Christina L Roark; Willi K Born
Protective role of gammadelta T cells in spontaneous ocular inflammation.
Investigative ophthalmology & visual science 2009;50(7):3266-74.
2009: Philip L Simonian; Christina L Roark; Fabian Wehrmann; Allison M Lanham; Willi K Born; Rebecca L O'Brien; Andrew P Fontenot
IL-17A-expressing T cells are essential for bacterial clearance in a murine model of hypersensitivity pneumonitis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6540-9.
2009: Rebecca L O'Brien; Christina L Roark; Willi K Born
IL-17-producing gammadelta T cells.
European journal of immunology 2009;39(3):662-6.
2009: Niyun Jin; Christina L Roark; Nobuaki Miyahara; Christian Taube; M Kemal Aydintug; JM Wands; Yafei Huang; Youn-Soo Hahn; Erwin W Gelfand; Rebecca L O'Brien; Willi K Born
Allergic airway hyperresponsiveness-enhancing gammadelta T cells develop in normal untreated mice and fail to produce IL-4/13, unlike Th2 and NKT cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2002-10.
2009: Philip L Simonian; Christina L Roark; Fabian Wehrmann; Allison K Lanham; Fernando Diaz del Valle; Willi K Born; Rebecca L O'Brien; Andrew P Fontenot
Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(1):657-65.
2008: M Kemal Aydintug; Christina L Roark; Jennifer L Chain; Willi K Born; Rebecca L O'Brien
Macrophages express multiple ligands for gammadelta TCRs.
Molecular immunology 2008;45(11):3253-63.
2008: Christina L Roark; Philip L Simonian; Andrew P Fontenot; Willi K Born; Rebecca L O'Brien
gammadelta T cells: an important source of IL-17.
Current opinion in immunology 2008;20(3):353-7.
2007: Christina L Roark; Jena D French; Molly A Taylor; Alison M Bendele; Willi K Born; Rebecca L O'Brien
Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5576-83.
2007: Niyun Jin; Nobuaki Miyahara; Christina L Roark; Jena D French; M Kemal Aydintug; Jennifer L Matsuda; Laurent Gapin; Rebecca L O'Brien; Erwin W Gelfand; Willi K Born
Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):2961-8.
2007: Willi K Born; Niyun Jin; M Kemal Aydintug; JM Wands; Jena D French; Christina L Roark; Rebecca L O'Brien
gammadelta T lymphocytes-selectable cells within the innate system?
Journal of clinical immunology 2007;27(2):133-44.
2007: Rebecca L O'Brien; Christina L Roark; Niyun Jin; M Kemal Aydintug; Jena D French; Jennifer L Chain; JM Wands; Molly Johnston; Willi K Born
gammadelta T-cell receptors: functional correlations.
Immunological reviews 2007;215():77-88.
2006: Philip L Simonian; Christina L Roark; Fernando Diaz del Valle; Brent E Palmer; Ivor S Douglas; Koichi Ikuta; Willi K Born; Rebecca L O'Brien; Andrew P Fontenot
Regulatory role of gammadelta T cells in the recruitment of CD4+ and CD8+ T cells to lung and subsequent pulmonary fibrosis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4436-43.
2005: JM Wands; Christina L Roark; M Kemal Aydintug; Niyun Jin; Youn-Soo Hahn; Laura Cook; Xiang Yin; Joseph Dal Porto; Michael Lahn; Dallas M Hyde; Erwin W Gelfand; Robert J Mason; Rebecca L O'Brien; Willi K Born
Distribution and leukocyte contacts of gammadelta T cells in the lung.
Journal of leukocyte biology 2005;78(5):1086-96.
2005: Jena D French; Christina L Roark; Willi K Born; Rebecca L O'Brien
{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14741-6.
2005: Michael T Falta; Andrew P Fontenot; Edward F Rosloniec; Frances Crawford; Christina L Roark; Jerome R Bill; Philippa Marrack; John Kappler; Brian L Kotzin
Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen.
Arthritis and rheumatism 2005;52(6):1885-96.
2005: Niyun Jin; Christian Taube; Laura Sharp; Youn-Soo Hahn; Xiang Yin; JM Wands; Christina L Roark; Rebecca L O'Brien; Erwin W Gelfand; Willi K Born
Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(5):2671-9.
2004: Rebecca M Tucker; Christina L Roark; Marie-Laure Santiago-Raber; Shozo Izui; Brian L Kotzin
Association between nuclear antigens and endogenous retrovirus in the generation of autoantibody responses in murine lupus.
Arthritis and rheumatism 2004;50(11):3626-36.
2004: M Kemal Aydintug; Christina L Roark; Xiang Yin; JM Wands; Willi K Born; Rebecca L O'Brien
Detection of cell surface ligands for the gamma delta TCR using soluble TCRs.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4167-75.
2004: Christina L Roark; M Kemal Aydintug; Julie Lewis; Xiang Yin; Michael Lahn; Youn-Soo Hahn; Willi K Born; Robert E Tigelaar; Rebecca L O'Brien
Subset-specific, uniform activation among V gamma 6/V delta 1+ gamma delta T cells elicited by inflammation.
Journal of leukocyte biology 2004;75(1):68-75.
2003: Youn-Soo Hahn; Christian Taube; Niyun Jin; Katsuyuki Takeda; Jung-Won Park; JM Wands; M Kemal Aydintug; Christina L Roark; Michael Lahn; Rebecca L O'Brien; Erwin W Gelfand; Willi K Born
V gamma 4+ gamma delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):3170-8.
2001: Christina L Roark; Brian L Kotzin
Characterization of CD4(+) T cell autoreactivity to self-MHC in New Zealand hybrid mice.
Clinical immunology (Orlando, Fla.) 2001;98(1):95-103.
2000: Rebecca M Tucker; Timothy J Vyse; Stephen Rozzo; Christina L Roark; Shozo Izui; Brian L Kotzin
Genetic control of glycoprotein 70 autoantigen production and its influence on immune complex levels and nephritis in murine lupus.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(3):1665-72.