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Francis Robert

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Z Nasr; John A Porco; Francis Robert; William J Muller; Jerry Pelletier
eIF4F suppression in breast cancer affects maintenance and progression.
Gabriela Galicia-Vázquez; Aouod Quang Agenor; Regina Cencic; Francis Robert; Jerry Pelletier
A cellular response linking eIF4AI activity to eIF4AII transcription.
Francis Robert; Michel L Tremblay; Dantong Wang; Simon S Wing; Aouod Agenor; Regina Cencic; Sergio DiMarco; Imed-Eddine Gallouzi; Siegfried Hekimi; John R Mills; Jerry Pelletier
Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival.

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All Publications

2013: Z Nasr; John A Porco; Francis Robert; William J Muller; Jerry Pelletier
eIF4F suppression in breast cancer affects maintenance and progression.
Oncogene 2013;32(7):861-71.
2012: Gabriela Galicia-Vázquez; Aouod Quang Agenor; Regina Cencic; Francis Robert; Jerry Pelletier
A cellular response linking eIF4AI activity to eIF4AII transcription.
RNA (New York, N.Y.) 2012;18(7):1373-84.
2012: Francis Robert; Michel L Tremblay; Dantong Wang; Simon S Wing; Aouod Agenor; Regina Cencic; Sergio DiMarco; Imed-Eddine Gallouzi; Siegfried Hekimi; John R Mills; Jerry Pelletier
Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival.
Cancer research 2012;72(3):747-56.
2011: Alexander S Wahba; Fereshteh Azizi; Claire Brown; Marilyn Carrier; Glen F Deleavey; Alan M Gewirtz; Robert H E Hudson; Anna Kalota; Jerry Pelletier; Francis Robert; Masad J Damha
Phenylpyrrolocytosine as an unobtrusive base modification for monitoring activity and cellular trafficking of siRNA.
ACS chemical biology 2011;6(9):912-9.
2011: Regina Cencic; David R Hall; Francis Robert; Yuhong Du; Jaeki Min; Lian Li; Min Qui; Iestyn Lewis; Serdar Kurtkaya; ray dingledine; Haian Fu; Dima Kozakov; Sandor Vajda; Jerry Pelletier
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(3):1046-51.
2009: Francis Robert; Jerry Pelletier
Translation initiation: a critical signalling node in cancer.
Expert opinion on therapeutic targets 2009;13(11):1279-93.
2009: Francis Robert; Chris Williams; Yifei Yan; Elizabeth Donohue; Regina Cencic; Stephen K Burley; Jerry Pelletier
Blocking UV-induced eIF2alpha phosphorylation with small molecule inhibitors of GCN2.
Chemical biology & drug design 2009;74(1):57-67.
2009: Michel Gravel; Francis Robert; Vicky Kottis; Imed-Eddine Gallouzi; Jerry Pelletier; Peter E Braun
2',3'-Cyclic nucleotide 3'-phosphodiesterase: a novel RNA-binding protein that inhibits protein synthesis.
Journal of neuroscience research 2009;87(5):1069-79.
2009: John A Beutler; Moon-Il Kang; Francis Robert; Jason A Clement; Jerry Pelletier; Nancy H Colburn; Tawnya C McKee; Ekaterina Goncharova; James B McMahon; Curtis J Henrich
Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition.
Journal of natural products 2009;72(3):503-6.
2009: Francis Robert; Marilyn Carrier; Svea Rawe; Samuel Chen; Scott W Lowe; Jerry Pelletier
Altering chemosensitivity by modulating translation elongation.
PloS one 2009;4(5):e5428.
2008: John R Mills; Yoshitaka Hippo; Francis Robert; Samuel M H Chen; Abba Malina; Chen-Ju Lin; Ulrike Trojahn; Hans-Guido Wendel; Al Charest; Roderick T Bronson; Scott C Kogan; Robert Nadon; David E Housman; Scott W Lowe; Jerry Pelletier
mTORC1 promotes survival through translational control of Mcl-1.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10853-8.
2008: Chen-Ju Lin; Regina Cencic; John R Mills; Francis Robert; Jerry Pelletier
c-Myc and eIF4F are components of a feedforward loop that links transcription and translation.
Cancer research 2008;68(13):5326-34.
2008: Marie-Eve Bordeleau; Francis Robert; Baudouin Gerard; Lisa Lindqvist; Samuel M H Chen; Hans-Guido Wendel; Brigitte Brem; Harald Greger; Scott W Lowe; John A Porco; Jerry Pelletier
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.
The Journal of clinical investigation 2008;118(7):2651-60.
2007: Regina Cencic; Francis Robert; Jerry Pelletier
Identifying small molecule inhibitors of eukaryotic translation initiation.
Methods in enzymology 2007;431():269-302.
2007: Jonathan K Watts; Niloufar Choubdar; Kashinath Sadalapure; Francis Robert; Alexander S Wahba; Jerry Pelletier; B Mario Pinto; Masad J Damha
2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity.
Nucleic acids research 2007;35(5):1441-51.
2006: Francis Robert; Lee Kapp; Shakila N Khan; Michael Acker; Sarah E Kolitz; Shirin Kazemi; Randal J Kaufman; William C Merrick; Antonis E Koromilas; Jon R Lorsch; Jerry Pelletier
Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2.GTP.Met-tRNA(i)(Met) ternary complex availability.
Molecular biology of the cell 2006;17(11):4632-44.
2006: Francis Robert; Hong Qing Gao; Marwa Donia; William C Merrick; Mark T Hamann; Jerry Pelletier
Chlorolissoclimides: new inhibitors of eukaryotic protein synthesis.
RNA (New York, N.Y.) 2006;12(5):717-25.