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Anita Roberts
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113
Sporn, Michael B.
38
Flanders, Kathleen
28
Kim, Seong-Jin
22
Lechleider, Robert
18
Danielpour, David
14
de Caestecker, Mark
13
Wakefield, Lalage
12
Parks, Tony
11
Letterio, John
9
Lafyatis, Robert
9
Piek, Ester
8
Burmester, James
8
Stuelten, Christina
6
Anzano, Mario
6
Böttinger, Erwin
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All Publications
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2009: Lin Huei-Min; Lee Ji-Hyeon; Yadav Hariom; Kamaraju Anil K; Liu Eric; Zhigang Duan; Vieira Anthony; Kim Seong-Jin; Collins Heather; Matschinsky Franz; Harlan David M; Roberts Anita B; Rane Sushil G
Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function.
The Journal of biological chemistry 2009;284(18):12246-57.
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2008: Stuelten Christina H; Barbul Adrian; Busch Johanna I; Sutton Emily; Katz Ryan; Sato Misako; Wakefield Lalage M; Roberts Anita B; Niederhuber John E
Acute wounds accelerate tumorigenesis by a T cell-dependent mechanism.
Cancer research 2008;68(18):7278-82.
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2008: Flanders Kathleen C; Ho Benjamin M; Arany Praveen R; Stuelten Christina; Mamura Mizuko; Paterniti Miya Okada; Sowers Anastasia; Mitchell James B; Roberts Anita B
Absence of Smad3 induces neutrophil migration after cutaneous irradiation: possible contribution to subsequent radioprotection.
The American journal of pathology 2008;173(1):68-76.
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2008: Arany P R; Rane S G; Roberts A B
Smad3 deficiency inhibits v-ras-induced transformation by suppression of JNK MAPK signaling and increased farnesyl transferase inhibition.
Oncogene 2008;27(17):2507-12.
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2007: Arany Praveen R; Flanders Kathleen C; DeGraff William; Cook John; Mitchell James B; Roberts Anita B
Absence of Smad3 confers radioprotection through modulation of ERK-MAPK in primary dermal fibroblasts.
Journal of dermatological science 2007;48(1):35-42.
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2007: Stuelten Christina H; Kamaraju Anil K; Wakefield Lalage M; Roberts Anita B
Lentiviral reporter constructs for fluorescence tracking of the temporospatial pattern of Smad3 signaling.
BioTechniques 2007;43(3):289-90, 292, 294.
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2006: Fujii Makiko; Lyakh Lyudmila A; Bracken Cameron P; Fukuoka Junya; Hayakawa Morisada; Tsukiyama Tadasuke; Soll Steven J; Harris Melissa; Rocha Sonia; Roche Kevin C; Tominaga Shin-ichi; Jen Jin; Perkins Neil D; Lechleider Robert J; Roberts Anita B
SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes.
Molecular cell 2006;24(5):771-83.
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2006: Arany Praveen R; Flanders Kathleen C; Kobayashi Tetsu; Kuo Catherine K; Stuelten Christina; Desai Kartiki V; Tuan Rocky; Rennard Stephen I; Roberts Anita B
Smad3 deficiency alters key structural elements of the extracellular matrix and mechanotransduction of wound closure.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9250-5.
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2006: Roberts Anita B; Tian Fang; Byfield Stacey DaCosta; Stuelten Christina; Ooshima Akira; Saika Shizuya; Flanders Kathleen C
Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.
Cytokine & growth factor reviews 2006;17(1-2):19-27.
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2006: Stuelten Christina H; Buck Miriam B; Dippon Juergen; Roberts Anita B; Fritz Peter; Knabbe Cornelius
Smad4-expression is decreased in breast cancer tissues: a retrospective study.
BMC cancer 2006;6():25.
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2005: Saika Shizuya; Yamanaka Osamu; Ikeda Kazuo; Kim-Mitsuyama Shokei; Flanders Kathleen C; Yoo Jiyun; Roberts Anita B; Nishikawa-Ishida Iku; Ohnishi Yoshitaka; Muragaki Yasuteru; Ooshima Akira
Inhibition of p38MAP kinase suppresses fibrotic reaction of retinal pigment epithelial cells.
Laboratory investigation; a journal of technical methods and pathology 2005;85(7):838-50.
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2005: Saika Shizuya; Ikeda Kazuo; Yamanaka Osamu; Miyamoto Takeshi; Ohnishi Yoshitaka; Sato Misako; Muragaki Yasuteru; Ooshima Akira; Nakajima Yuji; Kao Winston W-Y; Flanders Kathleen C; Roberts Anita B
Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali.
The American journal of pathology 2005;166(5):1405-18.
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2005: Stuelten Christina H; DaCosta Byfield Stacey; Arany Praveen R; Karpova Tatiana S; Stetler-Stevenson William G; Roberts Anita B
Breast cancer cells induce stromal fibroblasts to express MMP-9 via secretion of TNF-alpha and TGF-beta.
Journal of cell science 2005;118(Pt 10):2143-53.
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2005: Lyakh Lyudmila A; Sanford Michael; Chekol Sebel; Young Howard A; Roberts Anita B
TGF-beta and vitamin D3 utilize distinct pathways to suppress IL-12 production and modulate rapid differentiation of human monocytes into CD83+ dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(4):2061-70.
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2005: Kamaraju Anil K; Roberts Anita B
Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo.
The Journal of biological chemistry 2005;280(2):1024-36.
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2004: Saika Shizuya; Kono-Saika Satoko; Tanaka Takeshi; Yamanaka Osamu; Ohnishi Yoshitaka; Sato Misako; Muragaki Yasuteru; Ooshima Akira; Yoo Jiyun; Flanders Kathleen C; Roberts Anita B
Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice.
Laboratory investigation; a journal of technical methods and pathology 2004;84(10):1245-58.
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2004: Piek Ester; Van Dinther Maarten; Parks W Tony; Sallee John M; Böttinger Erwin P; Roberts Anita B; Ten Dijke Peter
RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta.
The Biochemical journal 2004;383(Pt 1):187-99.
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2004: Wolfraim Lawrence A; Fernandez Tania M; Mamura Mizuko; Fuller Walter L; Kumar Rajesh; Cole Diane E; Byfield Stacey; Felici Angelina; Flanders Kathleen C; Walz Thomas M; Roberts Anita B; Aplan Peter D; Balis Frank M; Letterio John J
Loss of Smad3 in acute T-cell lymphoblastic leukemia.
The New England journal of medicine 2004;351(6):552-9.
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2004: Tian Fang; Byfield Stacey DaCosta; Parks W Tony; Stuelten Christina H; Nemani Deepa; Zhang Ying E; Roberts Anita B
Smad-binding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines.
Cancer research 2004;64(13):4523-30.
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2004: Xavier Sandhya; Piek Ester; Fujii Makiko; Javelaud Delphine; Mauviel Alain; Flanders Kathy C; Samuni Ayelet M; Felici Angelina; Reiss Michael; Yarkoni Shai; Sowers Anastasia; Mitchell James B; Roberts Anita B; Russo Angelo
Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.
The Journal of biological chemistry 2004;279(15):15167-76.
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2004: Byfield Stacey DaCosta; Roberts Anita B
Lateral signaling enhances TGF-beta response complexity.
Trends in cell biology 2004;14(3):107-11.
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2004: DaCosta Byfield Stacey; Major Christopher; Laping Nicholas J; Roberts Anita B
SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7.
Molecular pharmacology 2004;65(3):744-52.
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2004: Saika Shizuya; Kono-Saika Satoko; Ohnishi Yoshitaka; Sato Misako; Muragaki Yasuteru; Ooshima Akira; Flanders Kathleen C; Yoo Jiyun; Anzano Mario; Liu Chia-Yang; Kao Winston W-Y; Roberts Anita B
Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury.
The American journal of pathology 2004;164(2):651-63.
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2003: Tian Fang; DaCosta Byfield Stacey; Parks W Tony; Yoo Stephen; Felici Angelina; Tang Binwu; Piek Ester; Wakefield Lalage M; Roberts Anita B
Reduction in Smad2/3 signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines.
Cancer research 2003;63(23):8284-92.
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2003: Flanders Kathleen C; Major Christopher D; Arabshahi Alidad; Aburime Ekinadese E; Okada Miya H; Fujii Makiko; Blalock Timothy D; Schultz Gregory S; Sowers Anastasia; Anzano Mario A; Mitchell James B; Russo Angelo; Roberts Anita B
Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin.
The American journal of pathology 2003;163(6):2247-57.
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2003: Ashcroft Gillian S; Mills Stuart J; Flanders Kathleen C; Lyakh Lyudmila A; Anzano Mario A; Gilliver Stephen C; Roberts Anita B
Role of Smad3 in the hormonal modulation of in vivo wound healing responses.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2003;11(6):468-73.
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2003: Yoo Jiyun; Ghiassi Mayshan; Jirmanova Ludmila; Balliet Arthur G; Hoffman Barbara; Fornace Albert J; Liebermann Dan A; Bottinger Erwin P; Roberts Anita B
Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation.
The Journal of biological chemistry 2003;278(44):43001-7.
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2003: Felici Angelina; Wurthner Jens U; Parks W Tony; Giam Louise Ruh-yu; Reiss Michael; Karpova Tatiana S; McNally James G; Roberts Anita B
TLP, a novel modulator of TGF-beta signaling, has opposite effects on Smad2- and Smad3-dependent signaling.
The EMBO journal 2003;22(17):4465-77.
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2003: Yang Yaw-Ching; Piek Ester; Zavadil Jiri; Liang Dan; Xie Donglu; Heyer Joerg; Pavlidis Paul; Kucherlapati Raju; Roberts Anita B; Böttinger Erwin P
Hierarchical model of gene regulation by transforming growth factor beta.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10269-74.
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2003: Roberts Anita B; Wakefield Lalage M
The two faces of transforming growth factor beta in carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8621-3.
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2003: Roberts Anita B; Russo Angelo; Felici Angelina; Flanders Kathleen C
Smad3: a key player in pathogenetic mechanisms dependent on TGF-beta.
Annals of the New York Academy of Sciences 2003;995():1-10.
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2003: Liu Xiangde; Wen Fu-Qiang; Kobayashi Tetsu; Abe Shinji; Fang Qiuhong; Piek Ester; Bottinger Erwin P; Roberts Anita B; Rennard Stephen I
Smad3 mediates the TGF-beta-induced contraction of type I collagen gels by mouse embryo fibroblasts.
Cell motility and the cytoskeleton 2003;54(3):248-53.
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2003: Cao Zhouhong; Flanders Kathleen C; Bertolette Daniel; Lyakh Lyudmila A; Wurthner Jens U; Parks W Tony; Letterio John J; Ruscetti Francis W; Roberts Anita B
Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-beta and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells.
Blood 2003;101(2):498-507.
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2002: de Caestecker Mark P; Bottomley Martyn; Bhattacharyya Sucharita; Payne Tracie L; Roberts Anita B; Yelick Pamela C
The novel type I serine-threonine kinase receptor Alk8 binds TGF-beta in the presence of TGF-betaRII.
Biochemical and biophysical research communications 2002;293(5):1556-65.
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2002: Flanders Kathleen C; Sullivan Catherine D; Fujii Makiko; Sowers Anastasia; Anzano Mario A; Arabshahi Alidad; Major Christopher; Deng Chuxia; Russo Angelo; Mitchell James B; Roberts Anita B
Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation.
The American journal of pathology 2002;160(3):1057-68.
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2002: Huang Shixia; Tang Binwu; Usoskin Dmitry; Lechleider Robert J; Jamin Soazik P; Li Cuiling; Anzano Mario A; Ebendal Ted; Deng Chuxia; Roberts Anita B
Conditional knockout of the Smad1 gene.
Genesis (New York, N.Y. : 2000) 2002;32(2):76-9.
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2002: Wakefield Lalage M; Roberts Anita B
TGF-beta signaling: positive and negative effects on tumorigenesis.
Current opinion in genetics & development 2002;12(1):22-9.
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2002: Roberts Anita B
The ever-increasing complexity of TGF-beta signaling.
Cytokine & growth factor reviews 2002;13(1):3-5.
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2001: Kim R H; Flanders K C; Birkey Reffey S; Anderson L A; Duckett C S; Perkins N D; Roberts A B
SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators.
The Journal of biological chemistry 2001;276(49):46297-304.
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2001: Roberts A B; Piek E; Böttinger E P; Ashcroft G; Mitchell J B; Flanders K C
Is Smad3 a major player in signal transduction pathways leading to fibrogenesis?
Chest 2001;120(1 Suppl):43S-47S.
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2001: Birkey Reffey S; Wurthner J U; Parks W T; Roberts A B; Duckett C S
X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling.
The Journal of biological chemistry 2001;276(28):26542-9.
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2001: Verrecchia F; Vindevoghel L; Lechleider R J; Uitto J; Roberts A B; Mauviel A
Smad3/AP-1 interactions control transcriptional responses to TGF-beta in a promoter-specific manner.
Oncogene 2001;20(26):3332-40.
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2001: Parks W T; Frank D B; Huff C; Renfrew Haft C; Martin J; Meng X; de Caestecker M P; McNally J G; Reddi A; Taylor S I; Roberts A B; Wang T; Lechleider R J
Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases.
The Journal of biological chemistry 2001;276(22):19332-9.
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2001: Wurthner J U; Frank D B; Felici A; Green H M; Cao Z; Schneider M D; McNally J G; Lechleider R J; Roberts A B
Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone.
The Journal of biological chemistry 2001;276(22):19495-502.
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2001: Piek E; Ju W J; Heyer J; Escalante-Alcalde D; Stewart C L; Weinstein M; Deng C; Kucherlapati R; Bottinger E P; Roberts A B
Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts.
The Journal of biological chemistry 2001;276(23):19945-53.
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2001: Lee D K; Park S H; Yi Y; Choi S G; Lee C; Parks W T; Cho H; de Caestecker M P; Shaul Y; Roberts A B; Kim S J
The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis.
Genes & development 2001;15(4):455-66.
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2001: Piek E; Roberts A B
Suppressor and oncogenic roles of transforming growth factor-beta and its signaling pathways in tumorigenesis.
Advances in cancer research 2001;83():1-54.
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2000: Larisch S; Yi Y; Lotan R; Kerner H; Eimerl S; Tony Parks W; Gottfried Y; Birkey Reffey S; de Caestecker M P; Danielpour D; Book-Melamed N; Timberg R; Duckett C S; Lechleider R J; Steller H; Orly J; Kim S J; Roberts A B
A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif.
Nature cell biology 2000;2(12):915-21.
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2000: Huang S; Flanders K C; Roberts A B
Characterization of the mouse Smad1 gene and its expression pattern in adult mouse tissues.
Gene 2000;258(1-2):43-53.
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2000: Tsang M; Kim R; de Caestecker M P; Kudoh T; Roberts A B; Dawid I B
Zebrafish nma is involved in TGFbeta family signaling.
Genesis (New York, N.Y. : 2000) 2000;28(2):47-57.
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2000: de Caestecker M P; Piek E; Roberts A B
Role of transforming growth factor-beta signaling in cancer.
Journal of the National Cancer Institute 2000;92(17):1388-402.
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2000: Kim R H; Wang D; Tsang M; Martin J; Huff C; de Caestecker M P; Parks W T; Meng X; Lechleider R J; Wang T; Roberts A B
A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction.
Genes & development 2000;14(13):1605-16.
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2000: Koch R M; Roche N S; Parks W T; Ashcroft G S; Letterio J J; Roberts A B
Incisional wound healing in transforming growth factor-beta1 null mice.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2000;8(3):179-91.
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2000: Yahata T; de Caestecker M P; Lechleider R J; Andriole S; Roberts A B; Isselbacher K J; Shioda T
The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors.
The Journal of biological chemistry 2000;275(12):8825-34.
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2000: Ashcroft G S; Roberts A B
Loss of Smad3 modulates wound healing.
Cytokine & growth factor reviews 2000;11(1-2):125-31.
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2000: Larisch-Bloch S; Danielpour D; Roche N S; Lotan R; Hsing A Y; Kerner H; Hajouj T; Lechleider R J; Roberts A B
Selective loss of the transforming growth factor-beta apoptotic signaling pathway in mutant NRP-154 rat prostatic epithelial cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2000;11(1):1-10.
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2000: de Caestecker M P; Yahata T; Wang D; Parks W T; Huang S; Hill C S; Shioda T; Roberts A B; Lechleider R J
The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain.
The Journal of biological chemistry 2000;275(3):2115-22.
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1999: Roberts A B
TGF-beta signaling from receptors to the nucleus.
Microbes and infection / Institut Pasteur 1999;1(15):1265-73.
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1999: Ashcroft G S; Yang X; Glick A B; Weinstein M; Letterio J L; Mizel D E; Anzano M; Greenwell-Wild T; Wahl S M; Deng C; Roberts A B
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response.
Nature cell biology 1999;1(5):260-6.
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1999: Maroulakou I G; Shibata M A; Anver M; Jorcyk C L; Liu M l; Roche N; Roberts A B; Tsarfaty I; Reseau J; Ward J; Green J E
Heterotopic endochondrial ossification with mixed tumor formation in C3(1)/Tag transgenic mice is associated with elevated TGF-beta1 and BMP-2 expression.
Oncogene 1999;18(39):5435-47.
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1999: Vodovotz Y; Chesler L; Chong H; Kim S J; Simpson J T; DeGraff W; Cox G W; Roberts A B; Wink D A; Barcellos-Hoff M H
Regulation of transforming growth factor beta1 by nitric oxide.
Cancer research 1999;59(9):2142-9.
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1999: Yang X; Letterio J J; Lechleider R J; Chen L; Hayman R; Gu H; Roberts A B; Deng C
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta.
The EMBO journal 1999;18(5):1280-91.
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1998: Vindevoghel L; Lechleider R J; Kon A; de Caestecker M P; Uitto J; Roberts A B; Mauviel A
SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14769-74.
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1998: Shioda T; Lechleider R J; Dunwoodie S L; Li H; Yahata T; de Caestecker M P; Fenner M H; Roberts A B; Isselbacher K J
Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(17):9785-90.
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1998: Zaher H; Fernandez-Salguero P M; Letterio J; Sheikh M S; Fornace A J; Roberts A B; Gonzalez F J
The involvement of aryl hydrocarbon receptor in the activation of transforming growth factor-beta and apoptosis.
Molecular pharmacology 1998;54(2):313-21.
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1998: de Caestecker M P; Parks W T; Frank C J; Castagnino P; Bottaro D P; Roberts A B; Lechleider R J
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases.
Genes & development 1998;12(11):1587-92.
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1998: Vindevoghel L; Kon A; Lechleider R J; Uitto J; Roberts A B; Mauviel A
Smad-dependent transcriptional activation of human type VII collagen gene (COL7A1) promoter by transforming growth factor-beta.
The Journal of biological chemistry 1998;273(21):13053-7.
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1998: Lucia M S; Sporn M B; Roberts A B; Stewart L V; Danielpour D
The role of transforming growth factor-beta1, -beta2, and -beta3 in androgen-responsive growth of NRP-152 rat prostatic epithelial cells.
Journal of cellular physiology 1998;175(2):184-92.
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1998: Shibata M A; Jorcyk C L; Devor D E; Yoshidome K; Rulong S; Resau J; Roche N; Roberts A B; Ward J M; Green J E
Altered expression of transforming growth factor betas during urethral and bulbourethral gland tumor progression in transgenic mice carrying the androgen-responsive C3(1) 5' flanking region fused to SV40 large T antigen.
Carcinogenesis 1998;19(1):195-205.
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1998: Amoroso S R; Huang N; Roberts A B; Potter M; Letterio J J
Consistent loss of functional transforming growth factor beta receptor expression in murine plasmacytomas.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):189-94.
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1997: de Caestecker M P; Hemmati P; Larisch-Bloch S; Ajmera R; Roberts A B; Lechleider R J
Characterization of functional domains within Smad4/DPC4.
The Journal of biological chemistry 1997;272(21):13690-6.
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1997: Böttinger E P; Letterio J J; Roberts A B
Biology of TGF-beta in knockout and transgenic mouse models.
Kidney international 1997;51(5):1355-60.
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1996: Qian S W; Burmester J K; Tsang M L; Weatherbee J A; Hinck A P; Ohlsen D J; Sporn M B; Roberts A B
Binding affinity of transforming growth factor-beta for its type II receptor is determined by the C-terminal region of the molecule.
The Journal of biological chemistry 1996;271(48):30656-62.
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1996: Letterio J J; Geiser A G; Kulkarni A B; Dang H; Kong L; Nakabayashi T; Mackall C L; Gress R E; Roberts A B
Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression.
The Journal of clinical investigation 1996;98(9):2109-19.
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1996: Vodovotz Y; Lucia M S; Flanders K C; Chesler L; Xie Q W; Smith T W; Weidner J; Mumford R; Webber R; Nathan C; Roberts A B; Lippa C F; Sporn M B
Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease.
The Journal of experimental medicine 1996;184(4):1425-33.
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1996: Vodovotz Y; Letterio J J; Geiser A G; Chesler L; Roberts A B; Sparrow J
Control of nitric oxide production by endogenous TGF-beta1 and systemic nitric oxide in retinal pigment epithelial cells and peritoneal macrophages.
Journal of leukocyte biology 1996;60(2):261-70.
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1996: Hinck A P; Archer S J; Qian S W; Roberts A B; Sporn M B; Weatherbee J A; Tsang M L; Lucas R; Zhang B L; Wenker J; Torchia D A
Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry 1996;35(26):8517-34.
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1996: Lechleider R J; de Caestecker M P; Dehejia A; Polymeropoulos M H; Roberts A B
Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1.
The Journal of biological chemistry 1996;271(30):17617-20.
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1996: Letterio J J; Roberts A B
Transforming growth factor-beta1-deficient mice: identification of isoform-specific activities in vivo.
Journal of leukocyte biology 1996;59(6):769-74.
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1996: Böttinger E P; Factor V M; Tsang M L; Weatherbee J A; Kopp J B; Qian S W; Wakefield L M; Roberts A B; Thorgeirsson S S; Sporn M B
The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(12):5877-82.
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1996: Vodovotz Y; Geiser A G; Chesler L; Letterio J J; Campbell A; Lucia M S; Sporn M B; Roberts A B
Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse.
The Journal of experimental medicine 1996;183(5):2337-42.
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1996: Anzano M A; Peer C W; Smith J M; Mullen L T; Shrader M W; Logsdon D L; Driver C L; Brown C C; Roberts A B; Sporn M B
Chemoprevention of mammary carcinogenesis in the rat: combined use of raloxifene and 9-cis-retinoic acid.
Journal of the National Cancer Institute 1996;88(2):123-5.
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1995: Bae H W; Geiser A G; Kim D H; Chung M T; Burmester J K; Sporn M B; Roberts A B; Kim S J
Characterization of the promoter region of the human transforming growth factor-beta type II receptor gene.
The Journal of biological chemistry 1995;270(49):29460-8.
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1995: Sanderson N; Factor V; Nagy P; Kopp J; Kondaiah P; Wakefield L; Roberts A B; Sporn M B; Thorgeirsson S S
Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2572-6.
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1994: Park K; Bae H; Heydemann A; Roberts A B; Dotto G P; Sporn M B; Kim S J
The E1A oncogene induces resistance to the effects of 1,25-dihydroxyvitamin D3 on inhibition of growth of mouse keratinocytes.
Cancer research 1994;54(23):6087-9.
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1994: Amatayakul-Chantler S; Qian S W; Gakenheimer K; Böttinger E P; Roberts A B; Sporn M B
[Ser77]transforming growth factor-beta 1. Selective biological activity and receptor binding in mink lung epithelial cells.
The Journal of biological chemistry 1994;269(44):27687-91.
-
1994: Qian S W; Burmester J K; Sun P D; Huang A; Ohlsen D J; Suardet L; Flanders K C; Davies D; Roberts A B; Sporn M B
Characterization of mutated transforming growth factor-beta s which possess unique biological properties.
Biochemistry 1994;33(40):12298-304.
-
1994: Park K; Kim S J; Bang Y J; Park J G; Kim N K; Roberts A B; Sporn M B
Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):8772-6.
-
1994: Anzano M A; Byers S W; Smith J M; Peer C W; Mullen L T; Brown C C; Roberts A B; Sporn M B
Prevention of breast cancer in the rat with 9-cis-retinoic acid as a single agent and in combination with tamoxifen.
Cancer research 1994;54(17):4614-7.
-
1994: Letterio J J; Geiser A G; Kulkarni A B; Roche N S; Sporn M B; Roberts A B
Maternal rescue of transforming growth factor-beta 1 null mice.
Science (New York, N.Y.) 1994;264(5167):1936-8.
-
1994: Ballock R T; Heydemann A; Wakefield L M; Flanders K C; Roberts A B; Sporn M B
Inhibition of the chondrocyte phenotype by retinoic acid involves upregulation of metalloprotease genes independent of TGF-beta.
Journal of cellular physiology 1994;159(2):340-6.
-
1994: Dey B R; Sukhatme V P; Roberts A B; Sporn M B; Rauscher F J; Kim S J
Repression of the transforming growth factor-beta 1 gene by the Wilms' tumor suppressor WT1 gene product.
Molecular endocrinology (Baltimore, Md.) 1994;8(5):595-602.
-
1994: Kim S J; Park K; Rudkin B B; Dey B R; Sporn M B; Roberts A B
Nerve growth factor induces transcription of transforming growth factor-beta 1 through a specific promoter element in PC12 cells.
The Journal of biological chemistry 1994;269(5):3739-44.
-
1993: Geiser A G; Letterio J J; Kulkarni A B; Karlsson S; Roberts A B; Sporn M B
Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):9944-8.
-
1993: Burmester J K; Qian S W; Roberts A B; Huang A; Amatayakul-Chantler S; Suardet L; Odartchenko N; Madri J A; Sporn M B
Characterization of distinct functional domains of transforming growth factor beta.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8628-32.
-
1993: Ballock R T; Heydemann A; Wakefield L M; Flanders K C; Roberts A B; Sporn M B
TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases.
Developmental biology 1993;158(2):414-29.
-
1993: Busam K J; Geiser A G; Roberts A B; Sporn M B
Synergistic increase of phorbol ester-induced c-fos mRNA expression by retinoic acid through stabilization of the c-fos message.
Oncogene 1993;8(8):2267-73.
-
1993: Geiser A G; Busam K J; Kim S J; Lafyatis R; O'Reilly M A; Webbink R; Roberts A B; Sporn M B
Regulation of the transforming growth factor-beta 1 and -beta 3 promoters by transcription factor Sp1.
Gene 1993;129(2):223-8.
-
1993: Romeo D S; Park K; Roberts A B; Sporn M B; Kim S J
An element of the transforming growth factor-beta 1 5'-untranslated region represses translation and specifically binds a cytosolic factor.
Molecular endocrinology (Baltimore, Md.) 1993;7(6):759-66.
-
1993: Archer S J; Bax A; Roberts A B; Sporn M B; Ogawa Y; Piez K A; Weatherbee J A; Tsang M L; Lucas R; Zheng B L
Transforming growth factor beta 1: secondary structure as determined by heteronuclear magnetic resonance spectroscopy.
Biochemistry 1993;32(4):1164-71.
-
1993: Archer S J; Bax A; Roberts A B; Sporn M B; Ogawa Y; Piez K A; Weatherbee J A; Tsang M L; Lucas R; Zheng B L
Transforming growth factor beta 1: NMR signal assignments of the recombinant protein expressed and isotopically enriched using Chinese hamster ovary cells.
Biochemistry 1993;32(4):1152-63.
-
1993: Roberts A B; Sporn M B
Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta).
Growth factors (Chur, Switzerland) 1993;8(1):1-9.
-
1992: Sporn M B; Roberts A B
Transforming growth factor-beta: recent progress and new challenges.
The Journal of cell biology 1992;119(5):1017-21.
-
1992: Roberts A B; Roche N S; Winokur T S; Burmester J K; Sporn M B
Role of transforming growth factor-beta in maintenance of function of cultured neonatal cardiac myocytes. Autocrine action and reversal of damaging effects of interleukin-1.
The Journal of clinical investigation 1992;90(5):2056-62.
-
1992: Roberts A B; Vodovotz Y; Roche N S; Sporn M B; Nathan C F
Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes.
Molecular endocrinology (Baltimore, Md.) 1992;6(11):1921-30.
-
1992: Busam K J; Roberts A B; Sporn M B
Inhibition of mitogen-induced c-fos expression in melanoma cells by retinoic acid involves the serum response element.
The Journal of biological chemistry 1992;267(28):19971-7.
-
1992: O'Reilly M A; Geiser A G; Kim S J; Bruggeman L A; Luu A X; Roberts A B; Sporn M B
Identification of an activating transcription factor (ATF) binding site in the human transforming growth factor-beta 2 promoter.
The Journal of biological chemistry 1992;267(28):19938-43.
-
1992: Sporn M B; Roberts A B
Autocrine secretion--10 years later.
Annals of internal medicine 1992;117(5):408-14.
-
1992: Jakowlew S B; Lechleider R; Geiser A G; Kim S J; Santa-Coloma T A; Cubert J; Sporn M B; Roberts A B
Identification and characterization of the chicken transforming growth factor-beta 3 promoter.
Molecular endocrinology (Baltimore, Md.) 1992;6(8):1285-98.
-
1992: Qian S W; Burmester J K; Merwin J R; Madri J A; Sporn M B; Roberts A B
Identification of a structural domain that distinguishes the actions of the type 1 and 2 isoforms of transforming growth factor beta on endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(14):6290-4.
-
1992: Kim S J; Park K; Koeller D; Kim K Y; Wakefield L M; Sporn M B; Roberts A B
Post-transcriptional regulation of the human transforming growth factor-beta 1 gene.
The Journal of biological chemistry 1992;267(19):13702-7.
-
1992: Kim S J; Kim K Y; Tapscott S J; Winokur T S; Park K; Fujiki H; Weintraub H; Roberts A B
Inhibition of protein phosphatases blocks myogenesis by first altering MyoD binding activity.
The Journal of biological chemistry 1992;267(21):15140-5.
-
1992: Roberts A B; McCune B K; Sporn M B
TGF-beta: regulation of extracellular matrix.
Kidney international 1992;41(3):557-9.
-
1992: Jakowlew S B; Cubert J; Danielpour D; Sporn M B; Roberts A B
Differential regulation of the expression of transforming growth factor-beta mRNAs by growth factors and retinoic acid in chicken embryo chondrocytes, myocytes, and fibroblasts.
Journal of cellular physiology 1992;150(2):377-85.
-
1992: Morales T I; Roberts A B
The interaction between retinoic acid and the transforming growth factors-beta in calf articular cartilage organ cultures.
Archives of biochemistry and biophysics 1992;293(1):79-84.
-
1992: Geiser A G; Burmester J K; Webbink R; Roberts A B; Sporn M B
Inhibition of growth by transforming growth factor-beta following fusion of two nonresponsive human carcinoma cell lines. Implication of the type II receptor in growth inhibitory responses.
The Journal of biological chemistry 1992;267(4):2588-93.
-
1992: O'Reilly M A; Danielpour D; Roberts A B; Sporn M B
Regulation of expression of transforming growth factor-beta 2 by transforming growth factor-beta isoforms is dependent upon cell type.
Growth factors (Chur, Switzerland) 1992;6(3):193-201.
-
1992: Roberts A B; Sporn M B
Mechanistic interrelationships between two superfamilies: the steroid/retinoid receptors and transforming growth factor-beta.
Cancer surveys 1992;14():205-20.
-
1991: Kim S J; Winokur T S; Lee H D; Danielpour D; Kim K Y; Geiser A G; Chen L S; Sporn M B; Roberts A B; Jay G
Overexpression of transforming growth factor-beta in transgenic mice carrying the human T-cell lymphotropic virus type I tax gene.
Molecular and cellular biology 1991;11(10):5222-8.
-
1991: Flanders K C; Lüdecke G; Engels S; Cissel D S; Roberts A B; Kondaiah P; Lafyatis R; Sporn M B; Unsicker K
Localization and actions of transforming growth factor-beta s in the embryonic nervous system.
Development (Cambridge, England) 1991;113(1):183-91.
-
1991: Morales T I; Joyce M E; Sobel M E; Danielpour D; Roberts A B
Transforming growth factor-beta in calf articular cartilage organ cultures: synthesis and distribution.
Archives of biochemistry and biophysics 1991;288(2):397-405.
-
1991: Jakowlew S B; Mead J E; Danielpour D; Wu J; Roberts A B; Fausto N
Transforming growth factor-beta (TGF-beta) isoforms in rat liver regeneration: messenger RNA expression and activation of latent TGF-beta.
Cell regulation 1991;2(7):535-48.
-
1991: Lafyatis R; Lechleider R; Roberts A B; Sporn M B
Secretion and transcriptional regulation of transforming growth factor-beta 3 during myogenesis.
Molecular and cellular biology 1991;11(7):3795-803.
-
1991: Heine U I; Burmester J K; Flanders K C; Danielpour D; Munoz E F; Roberts A B; Sporn M B
Localization of transforming growth factor-beta 1 in mitochondria of murine heart and liver.
Cell regulation 1991;2(6):467-77.
-
1991: Kim S J; Lee H D; Robbins P D; Busam K; Sporn M B; Roberts A B
Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3052-6.
-
1991: Qian S W; Kondaiah P; Casscells W; Roberts A B; Sporn M B
A second messenger RNA species of transforming growth factor beta 1 in infarcted rat heart.
Cell regulation 1991;2(3):241-9.
-
1991: Sporn M B; Roberts A B
Interactions of retinoids and transforming growth factor-beta in regulation of cell differentiation and proliferation.
Molecular endocrinology (Baltimore, Md.) 1991;5(1):3-7.
-
1991: Geiser A G; Kim S J; Roberts A B; Sporn M B
Characterization of the mouse transforming growth factor-beta 1 promoter and activation by the Ha-ras oncogene.
Molecular and cellular biology 1991;11(1):84-92.
-
1991: Jakowlew S B; Dillard P J; Winokur T S; Flanders K C; Sporn M B; Roberts A B
Expression of transforming growth factor-beta s 1-4 in chicken embryo chondrocytes and myocytes.
Developmental biology 1991;143(1):135-48.
-
1991: Sporn M B; Roberts A B
Introduction: what is TGF-beta?
Ciba Foundation symposium 1991;157():1-6.
-
1991: Roberts A B; Kim S J; Noma T; Glick A B; Lafyatis R; Lechleider R; Jakowlew S B; Geiser A; O'Reilly M A; Danielpour D
Multiple forms of TGF-beta: distinct promoters and differential expression.
Ciba Foundation symposium 1991;157():7-15; discussion 15-28.
-
1991: Noma T; Glick A B; Geiser A G; O'Reilly M A; Miller J; Roberts A B; Sporn M B
Molecular cloning and structure of the human transforming growth factor-beta 2 gene promoter.
Growth factors (Chur, Switzerland) 1991;4(4):247-55.
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1990: Lafyatis R; Lechleider R; Kim S J; Jakowlew S; Roberts A B; Sporn M B
Structural and functional characterization of the transforming growth factor beta 3 promoter. A cAMP-responsive element regulates basal and induced transcription.
The Journal of biological chemistry 1990;265(31):19128-36.
-
1990: Sporn M B; Roberts A B
TGF-beta: problems and prospects.
Cell regulation 1990;1(12):875-82.
-
1990: Birchenall-Roberts M C; Ruscetti F W; Kasper J; Lee H D; Friedman R; Geiser A; Sporn M B; Roberts A B; Kim S J
Transcriptional regulation of the transforming growth factor beta 1 promoter by v-src gene products is mediated through the AP-1 complex.
Molecular and cellular biology 1990;10(9):4978-83.
-
1990: Kim S J; Kehrl J H; Burton J; Tendler C L; Jeang K T; Danielpour D; Thevenin C; Kim K Y; Sporn M B; Roberts A B
Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia.
The Journal of experimental medicine 1990;172(1):121-9.
-
1990: Lafyatis R; Kim S J; Angel P; Roberts A B; Sporn M B; Karin M; Wilder R L
Interleukin-1 stimulates and all-trans-retinoic acid inhibits collagenase gene expression through its 5' activator protein-1-binding site.
Molecular endocrinology (Baltimore, Md.) 1990;4(7):973-80.
-
1990: Joyce M E; Roberts A B; Sporn M B; Bolander M E
Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur.
The Journal of cell biology 1990;110(6):2195-207.
-
1990: Qian S W; Kondaiah P; Roberts A B; Sporn M B
cDNA cloning by PCR of rat transforming growth factor beta-1.
Nucleic acids research 1990;18(10):3059.
-
1990: Heine U I; Munoz E F; Flanders K C; Roberts A B; Sporn M B
Colocalization of TGF-beta 1 and collagen I and III, fibronectin and glycosaminoglycans during lung branching morphogenesis.
Development (Cambridge, England) 1990;109(1):29-36.
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1990: Kim S J; Angel P; Lafyatis R; Hattori K; Kim K Y; Sporn M B; Karin M; Roberts A B
Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex.
Molecular and cellular biology 1990;10(4):1492-7.
-
1990: Roberts A B; Flanders K C; Heine U I; Jakowlew S; Kondaiah P; Kim S J; Sporn M B
Transforming growth factor-beta: multifunctional regulator of differentiation and development.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1990;327(1239):145-54.
-
1990: Kim S J; Lafyatis R; Kim K Y; Angel P; Fujiki H; Karin M; Sporn M B; Roberts A B
Regulation of collagenase gene expression by okadaic acid, an inhibitor of protein phosphatases.
Cell regulation 1990;1(3):269-78.
-
1990: Kondaiah P; Sands M J; Smith J M; Fields A; Roberts A B; Sporn M B; Melton D A
Identification of a novel transforming growth factor-beta (TGF-beta 5) mRNA in Xenopus laevis.
The Journal of biological chemistry 1990;265(2):1089-93.
-
1990: Flanders K C; Cissel D S; Mullen L T; Danielpour D; Sporn M B; Roberts A B
Antibodies to transforming growth factor-beta 2 peptides: specific detection of TGF-beta 2 in immunoassays.
Growth factors (Chur, Switzerland) 1990;3(1):45-52.
-
1990: Roberts A B; Rosa F; Roche N S; Coligan J E; Garfield M; Rebbert M L; Kondaiah P; Danielpour D; Kehrl J H; Wahl S M
Isolation and characterization of TGF-beta 2 and TGF-beta 5 from medium conditioned by Xenopus XTC cells.
Growth factors (Chur, Switzerland) 1990;2(2-3):135-47.
-
1990: Jakowlew S B; Dillard P J; Sporn M B; Roberts A B
Complementary deoxyribonucleic acid cloning of an mRNA encoding transforming growth factor-beta 2 from chicken embryo chondrocytes.
Growth factors (Chur, Switzerland) 1990;2(2-3):123-33.
-
1990: Roberts A B; Kondaiah P; Rosa F; Watanabe S; Good P; Danielpour D; Roche N S; Rebbert M L; Dawid I B; Sporn M B
Mesoderm induction in Xenopus laevis distinguishes between the various TGF-beta isoforms.
Growth factors (Chur, Switzerland) 1990;3(4):277-86.
-
1990: Denhez F; Lafyatis R; Kondaiah P; Roberts A B; Sporn M B
Cloning by polymerase chain reaction of a new mouse TGF-beta, mTGF-beta 3.
Growth factors (Chur, Switzerland) 1990;3(2):139-46.
-
1990: Roberts A B; Kim S J; Kondaiah P; Jakowlew S B; Denhez F; Glick A B; Geiser A G; Watanabe S; Noma T; Lechleider R
Transcriptional control of expression of the TGF-betas.
Annals of the New York Academy of Sciences 1990;593():43-50.
-
1990: Sporn M B; Roberts A B
The transforming growth factor-betas: past, present, and future.
Annals of the New York Academy of Sciences 1990;593():1-6.
-
1990: Roberts A B; Heine U I; Flanders K C; Sporn M B
Transforming growth factor-beta. Major role in regulation of extracellular matrix.
Annals of the New York Academy of Sciences 1990;580():225-32.
-
1990: Heine U I; Wahl S M; Munoz E F; Allen J B; Ellingsworth L R; Flanders K C; Roberts A B; Sporn M B
Transforming growth factor-beta 1 specifically localizes in elastin during synovial inflammation: an immunoelectron microscopic study.
Archiv für Geschwulstforschung 1990;60(4):289-94.
-
1989: Kim S J; Denhez F; Kim K Y; Holt J T; Sporn M B; Roberts A B
Activation of the second promoter of the transforming growth factor-beta 1 gene by transforming growth factor-beta 1 and phorbol ester occurs through the same target sequences.
The Journal of biological chemistry 1989;264(32):19373-8.
-
1989: Roberts A B; Sporn M B
Regulation of endothelial cell growth, architecture, and matrix synthesis by TGF-beta.
The American review of respiratory disease 1989;140(4):1126-8.
-
1989: Sporn M B; Roberts A B
Transforming growth factor-beta. Multiple actions and potential clinical applications.
JAMA : the journal of the American Medical Association 1989;262(7):938-41.
-
1989: Connor T B; Roberts A B; Sporn M B; Danielpour D; Dart L L; Michels R G; de Bustros S; Enger C; Kato H; Lansing M
Correlation of fibrosis and transforming growth factor-beta type 2 levels in the eye.
The Journal of clinical investigation 1989;83(5):1661-6.
-
1989: Kim S J; Jeang K T; Glick A B; Sporn M B; Roberts A B
Promoter sequences of the human transforming growth factor-beta 1 gene responsive to transforming growth factor-beta 1 autoinduction.
The Journal of biological chemistry 1989;264(12):7041-5.
-
1989: Thompson N L; Flanders K C; Smith J M; Ellingsworth L R; Roberts A B; Sporn M B
Expression of transforming growth factor-beta 1 in specific cells and tissues of adult and neonatal mice.
The Journal of cell biology 1989;108(2):661-9.
-
1989: Flanders K C; Thompson N L; Cissel D S; Van Obberghen-Schilling E; Baker C C; Kass M E; Ellingsworth L R; Roberts A B; Sporn M B
Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.
The Journal of cell biology 1989;108(2):653-60.
-
1989: Danielpour D; Dart L L; Flanders K C; Roberts A B; Sporn M B
Immunodetection and quantitation of the two forms of transforming growth factor-beta (TGF-beta 1 and TGF-beta 2) secreted by cells in culture.
Journal of cellular physiology 1989;138(1):79-86.
-
1989: Kim S J; Glick A; Sporn M B; Roberts A B
Characterization of the promoter region of the human transforming growth factor-beta 1 gene.
The Journal of biological chemistry 1989;264(1):402-8.
-
1989: Sporn M B; Roberts A B; Wakefield L M; Glick A B; Danielpour D
Transforming growth factor-beta and suppression of carcinogenesis.
Princess Takamatsu symposia 1989;20():259-66.
-
1989: Danielpour D; Kim K Y; Dart L L; Watanabe S; Roberts A B; Sporn M B
Sandwich enzyme-linked immunosorbent assays (SELISAs) quantitate and distinguish two forms of transforming growth factor-beta (TGF-beta 1 and TGF-beta 2) in complex biological fluids.
Growth factors (Chur, Switzerland) 1989;2(1):61-71.
-
1988: Jakowlew S B; Dillard P J; Sporn M B; Roberts A B
Complementary deoxyribonucleic acid cloning of a messenger ribonucleic acid encoding transforming growth factor beta 4 from chicken embryo chondrocytes.
Molecular endocrinology (Baltimore, Md.) 1988;2(12):1186-95.
-
1988: Kondaiah P; Van Obberghen-Schilling E; Ludwig R L; Dhar R; Sporn M B; Roberts A B
cDNA cloning of porcine transforming growth factor-beta 1 mRNAs. Evidence for alternate splicing and polyadenylation.
The Journal of biological chemistry 1988;263(34):18313-7.
-
1988: Jakowlew S B; Kondaiah P; Dillard P J; Sporn M B; Roberts A B
A novel low molecular weight ribonucleic acid (RNA) related to transforming growth factor alpha messenger RNA.
Molecular endocrinology (Baltimore, Md.) 1988;2(11):1056-63.
-
1988: Jakowlew S B; Dillard P J; Sporn M B; Roberts A B
Nucleotide sequence of chicken transforming growth factor-beta 1 (TGF-beta 1).
Nucleic acids research 1988;16(17):8730.
-
1988: Morales T I; Roberts A B
Transforming growth factor beta regulates the metabolism of proteoglycans in bovine cartilage organ cultures.
The Journal of biological chemistry 1988;263(26):12828-31.
-
1988: Gabrielson E W; Gerwin B I; Harris C C; Roberts A B; Sporn M B; Lechner J F
Stimulation of DNA synthesis in cultured primary human mesothelial cells by specific growth factors.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(11):2717-21.
-
1988: Jakowlew S B; Dillard P J; Kondaiah P; Sporn M B; Roberts A B
Complementary deoxyribonucleic acid cloning of a novel transforming growth factor-beta messenger ribonucleic acid from chick embryo chondrocytes.
Molecular endocrinology (Baltimore, Md.) 1988;2(8):747-55.
-
1988: Van Obberghen-Schilling E; Roche N S; Flanders K C; Sporn M B; Roberts A B
Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.
The Journal of biological chemistry 1988;263(16):7741-6.
-
1988: Roberts A B; Thompson N L; Heine U; Flanders C; Sporn M B
Transforming growth factor-beta: possible roles in carcinogenesis.
British journal of cancer 1988;57(6):594-600.
-
1988: Sporn M B; Roberts A B
Peptide growth factors are multifunctional.
Nature 1988;332(6161):217-9.
-
1988: Rosa F; Roberts A B; Danielpour D; Dart L L; Sporn M B; Dawid I B
Mesoderm induction in amphibians: the role of TGF-beta 2-like factors.
Science (New York, N.Y.) 1988;239(4841 Pt 1):783-5.
-
1988: Rossi P; Karsenty G; Roberts A B; Roche N S; Sporn M B; de Crombrugghe B
A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-beta.
Cell 1988;52(3):405-14.
-
1988: Sporn M B; Roberts A B
Transforming growth factor-beta: new chemical forms and new biological roles.
BioFactors (Oxford, England) 1988;1(1):89-93.
-
1988: Flanders K C; Roberts A B; Ling N; Fleurdelys B E; Sporn M B
Antibodies to peptide determinants in transforming growth factor beta and their applications.
Biochemistry 1988;27(2):739-46.
-
1988: Jakowlew S B; Kondaiah P; Flanders K C; Thompson N L; Dillard P J; Sporn M B; Roberts A B
Increased expression of growth factor mRNAs accompanies viral transformation of rodent cells.
Oncogene research 1988;2(2):135-48.
-
1988: Roberts A B; Flanders K C; Kondaiah P; Thompson N L; Van Obberghen-Schilling E; Wakefield L; Rossi P; de Crombrugghe B; Heine U; Sporn M B
Transforming growth factor beta: biochemistry and roles in embryogenesis, tissue repair and remodeling, and carcinogenesis.
Recent progress in hormone research 1988;44():157-97.
-
1988: Roberts A B; Sporn M B
Transforming growth factor beta.
Advances in cancer research 1988;51():107-45.
-
1988: Mulé J J; Schwarz S L; Roberts A B; Sporn M B; Rosenberg S A
Transforming growth factor-beta inhibits the in vitro generation of lymphokine-activated killer cells and cytotoxic T cells.
Cancer immunology, immunotherapy : CII 1988;26(2):95-100.
-
1987: Gerwin B I; Lechner J F; Reddel R R; Roberts A B; Robbins K C; Gabrielson E W; Harris C C
Comparison of production of transforming growth factor-beta and platelet-derived growth factor by normal human mesothelial cells and mesothelioma cell lines.
Cancer research 1987;47(23):6180-4.
-
1987: Heine U; Munoz E F; Flanders K C; Ellingsworth L R; Lam H Y; Thompson N L; Roberts A B; Sporn M B
Role of transforming growth factor-beta in the development of the mouse embryo.
The Journal of cell biology 1987;105(6 Pt 2):2861-76.
-
1987: Sporn M B; Roberts A B; Wakefield L M; de Crombrugghe B
Some recent advances in the chemistry and biology of transforming growth factor-beta.
The Journal of cell biology 1987;105(3):1039-45.
-
1987: Robey P G; Young M F; Flanders K C; Roche N S; Kondaiah P; Reddi A H; Termine J D; Sporn M B; Roberts A B
Osteoblasts synthesize and respond to transforming growth factor-type beta (TGF-beta) in vitro.
The Journal of cell biology 1987;105(1):457-63.
-
1987: Roberts A B; Sporn M B
Transforming growth factor-beta: potential common mechanisms mediating its effects on embryogenesis, inflammation-repair, and carcinogenesis.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1987;14(4):435-9.
-
1986: Sporn M B; Roberts A B; Wakefield L M; Assoian R K
Transforming growth factor-beta: biological function and chemical structure.
Science (New York, N.Y.) 1986;233(4763):532-4.
-
1986: Roberts A B; Sporn M B; Assoian R K; Smith J M; Roche N S; Wakefield L M; Heine U I; Liotta L A; Falanga V; Kehrl J H
Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(12):4167-71.
-
1986: Stern D F; Roberts A B; Roche N S; Sporn M B; Weinberg R A
Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factor.
Molecular and cellular biology 1986;6(3):870-7.
-
1986: Wakefield L M; Roberts A B; Assoian R K; Fanger B O; Masui T; Lechner J F; Harris C C; Sporn M B
Structure and function of transforming growth factor-beta.
Proceedings of the Western Pharmacology Society 1986;29():475-7.
-
1985: Roberts A B; Anzano M A; Wakefield L M; Roche N S; Stern D F; Sporn M B
Type beta transforming growth factor: a bifunctional regulator of cellular growth.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(1):119-23.
-
1985: Anzano M A; Roberts A B; De Larco J E; Wakefield L M; Assoian R K; Roche N S; Smith J M; Lazarus J E; Sporn M B
Increased secretion of type beta transforming growth factor accompanies viral transformation of cells.
Molecular and cellular biology 1985;5(1):242-7.
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1985: Sporn M B; Roberts A B
Autocrine, paracrine and endocrine mechanisms of growth control.
Cancer surveys 1985;4(4):627-32.
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1985: Roberts A B; Sporn M B
Transforming growth factors.
Cancer surveys 1985;4(4):683-705.
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1985: Heine U I; Roberts A B; Munoz E F; Roche N S; Sporn M B
Effects of retinoid deficiency on the development of the heart and vascular system of the quail embryo.
Virchows Archiv. B, Cell pathology including molecular pathology 1985;50(2):135-52.
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1983: Anzano M A; Roberts A B; Smith J M; Sporn M B; De Larco J E
Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(20):6264-8.
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