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Jason Roberts

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Andrew A Udy; Jean-Louis Vincent; Fabio Silvio Taccone; Cecilia Covajes; Frédérique Jacobs; Jeffrey Lipman; Jason A Roberts
Can population pharmacokinetic modelling guide vancomycin dosing during continuous renal replacement therapy in critically ill patients?
Andrew A Udy; Jason A Roberts; Jeffrey Lipman
How should we dose antibiotics for pneumonia in the ICU?
Kiran Shekar; Maree T Smith; Steven C Wallis; Sussan Ghassabian; Daniel V Mullany; Jason A Roberts; John F Fraser
Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?

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All Publications

2013: Andrew A Udy; Jean-Louis Vincent; Fabio Silvio Taccone; Cecilia Covajes; Frédérique Jacobs; Jeffrey Lipman; Jason A Roberts
Can population pharmacokinetic modelling guide vancomycin dosing during continuous renal replacement therapy in critically ill patients?
International journal of antimicrobial agents 2013;41(6):564-8.
2013: Andrew A Udy; Jason A Roberts; Jeffrey Lipman
How should we dose antibiotics for pneumonia in the ICU?
Current opinion in infectious diseases 2013;26(2):189-95.
2013: Kiran Shekar; Maree T Smith; Steven C Wallis; Sussan Ghassabian; Daniel V Mullany; Jason A Roberts; John F Fraser
Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?
The Journal of antimicrobial chemotherapy 2013;68(3):726-7.
2013: Jason A Roberts; Jeffrey Lipman
Optimal doripenem dosing simulations in critically ill nosocomial pneumonia patients with obesity, augmented renal clearance, and decreased bacterial susceptibility.
Critical care medicine 2013;41(2):489-95.
2013: Yoshiro Hayashi; Jeffrey Lipman; Karin Lust; Brett McWhinney; Mandy Ng; Andrew A Udy; Jacobus Ungerer; Jason A Roberts
β-Lactam therapeutic drug monitoring in the critically ill: optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia.
International journal of antimicrobial agents 2013;41(2):162-6.
2013: Kiran Shekar; Maree T Smith; YL Fung; Jason A Roberts; John F Fraser
The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation.
BMC anesthesiology 2013;13():7.
2013: Jason A Roberts; Federico Pea; Jeffrey Lipman
The clinical relevance of plasma protein binding changes.
Clinical pharmacokinetics 2013;52(1):1-8.
2013: Joel M Dulhunty; Glenn M Eastwood; Charles Gomersall; John Myburgh; David L Paterson; Jason A Roberts; Charudatt Shirwadkar; Steven A R Webb; Rinaldo Bellomo; Joshua S Davis; Jeffrey Lipman
Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicenter double-blind, randomized controlled trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013;56(2):236-44.
2012: Iain J Abbott; Jason A Roberts
Infusional β-lactam antibiotics in febrile neutropenia: has the time come?
Current opinion in infectious diseases 2012;25(6):619-25.
2012: Kiran Shekar; Maree T Smith; John F Fraser; Jason A Roberts
Pharmacokinetic changes in patients receiving extracorporeal membrane oxygenation.
Journal of critical care 2012;27(6):741.e9-18.
2012: Janattul-Ain Jamal; Jeffrey Lipman; Caleb J P Economou; Jason A Roberts
Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation.
Current opinion in critical care 2012;18(5):460-71.
2012: Julie M Varghese; Steven C Wallis; Jason A Roberts; Robert J Boots; Robert G Fassett; Helen Healy; Jeffrey Lipman; Dwarakanathan Ranganathan
Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study).
Clinical journal of the American Society of Nephrology : CJASN 2012;7(8):1249-56.
2012: Bhavik M Patel; David L Paterson; Michael Rudd; Jeffrey Lipman; Anthony Mallet; Michael J Muller; Jennifer Paratz; Jason A Roberts
Characteristics of bloodstream infections in burn patients: An 11-year retrospective study.
Burns : journal of the International Society for Burn Injuries 2012;38(5):685-90.
2012: Sukhpreet Kaur; Jason A Roberts; Michael S Roberts
Evaluation of medication-related problems in medication reviews: a comparative perspective.
The Annals of pharmacotherapy 2012;46(7-8):972-82.
2012: Andrew A Udy; Jacobus P Ungerer; Julie M Varghese; Mahdi Altukroni; Scott Briscoe; Jeffrey Lipman; Brett C McWhinney; Jason A Roberts
Subtherapeutic initial β-lactam concentrations in select critically ill patients: association between augmented renal clearance and low trough drug concentrations.
Chest 2012;142(1):30-9.
2012: Mahipal G Sinnollareddy; Michael S Roberts; Jeffrey Lipman; Jason A Roberts
β-lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: a structured review.
Clinical and experimental pharmacology & physiology 2012;39(6):489-96.
2012: Andrew A Udy; Jan J De Waele; David L Paterson; Jason A Roberts; Jeffrey Lipman
What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance.
International journal of antimicrobial agents 2012;39(6):455-7.
2012: Jason A Roberts; Jeffrey Lipman
Editorial commentary: Closing the loop--a colistin clinical study to confirm dosing recommendations from PK/PD modeling.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012;54(12):1727-9.
2012: Darren M Roberts; Jason A Roberts; Michael S Roberts; Rinaldo Bellomo; Louise Cole; Jeffrey Lipman; Xin Liu; Priya Nair
Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: a multicentre pharmacokinetic study.
Critical care medicine 2012;40(5):1523-8.
2012: Bhavik M Patel; David Paterson; Michael Rudd; Natalie C See; Jacobus Ungerer; Scott E Briscoe; Jeffrey Lipman; Brett C McWhinney; Michael J Muller; Jennifer Paratz; Jason A Roberts
Therapeutic drug monitoring of beta-lactam antibiotics in burns patients--a one-year prospective study.
Therapeutic drug monitoring 2012;34(2):160-4.
2012: Jason A Roberts; Gordon Y S Choi; Charles D Gomersall; Gavin M Joynt; Jeffrey Lipman
How to optimise antimicrobial prescriptions in the Intensive Care Unit: principles of individualised dosing using pharmacokinetics and pharmacodynamics.
International journal of antimicrobial agents 2012;39(3):187-92.
2012: Syamhanin Adnan; Suresh Kumar; Janice Li; Jeffrey Lipman; David L Paterson; Michael Rudd; Jason A Roberts
Pharmacokinetics of beta-lactam antibiotics in patients with intra-abdominal disease: a structured review.
Surgical infections 2012;13(1):9-17.
2012: Kiran Shekar; Maree T Smith; Steven C Wallis; James Walsham; Susan Welch; Adrian G Barnett; Fay Burrows; Hergen Buscher; YL Fung; Sussan Ghassabian; Eileen Gilder; Bianca Levkovich; Shay McGuinness; Daniel V Mullany; Rachael Parke; Vin Pellegrino; Jason A Roberts; Sam Rudham; John F Fraser
ASAP ECMO: Antibiotic, Sedative and Analgesic Pharmacokinetics during Extracorporeal Membrane Oxygenation: a multi-centre study to optimise drug therapy during ECMO.
BMC anesthesiology 2012;12():29.
2012: Mohd H Abdul-Aziz; Rinaldo Bellomo; Joel M Dulhunty; Jeffrey Lipman; Jason A Roberts
Continuous beta-lactam infusion in critically ill patients: the clinical evidence.
Annals of intensive care 2012;2(1):37.
2012: Fekade Bruck Sime; Michael S Roberts; Jeffrey Lipman; Sandra L Peake; Jason A Roberts
Does Beta-lactam Pharmacokinetic Variability in Critically Ill Patients Justify Therapeutic Drug Monitoring? A Systematic Review.
Annals of intensive care 2012;2(1):35.
2012: Jason A Roberts; Therese Starr; Steven C Wallis; Jan J De Waele; George Dimopoulos; DESPOINA KOULENTI; Claude Martin; Philippe Montravers; jordi rello; Andrew Rhodes; Jeffrey Lipman
DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic.
BMC infectious diseases 2012;12():152.
2012: Jason A Roberts; Ross Norris; David L Paterson; Jennifer H Martin
Therapeutic drug monitoring of antimicrobials.
British journal of clinical pharmacology 2012;73(1):27-36.
2011: Jason A Roberts
Relevance of pharmacokinetics to antibiotic dosing in critically ill patients.
Current pharmaceutical biotechnology 2011;12(12):1981-2.
2011: Kashyap Patel; Jason A Roberts; Susan E Tett; Megan E Deldot; Jeffrey Lipman; Carl M J Kirkpatrick
Population pharmacokinetics of fluconazole in critically ill patients receiving continuous venovenous hemodiafiltration: using Monte Carlo simulations to predict doses for specified pharmacodynamic targets.
Antimicrobial agents and chemotherapy 2011;55(12):5868-73.
2011: Jason A Roberts
Using PK/PD to optimize antibiotic dosing for critically ill patients.
Current pharmaceutical biotechnology 2011;12(12):2070-9.
2011: Alexandra Douglas; Paul Jarrett; Jason Jenkins; Melissa Lassig-Smith; Jeffrey Lipman; Gregory Medley; Michael S Roberts; Janine Stuart; Kersi Taraporewalla; Andrew A Udy; Steven C Wallis; Renae Deans; Jason A Roberts
Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery.
Antimicrobial agents and chemotherapy 2011;55(11):5238-42.
2011: Andrew A Udy; Jason A Roberts; Jeffrey Lipman
Implications of augmented renal clearance in critically ill patients.
Nature reviews. Nephrology 2011;7(9):539-43.
2011: Jason A Roberts; Fabio Silvio Taccone; Andrew A Udy; Jean-Louis Vincent; Frédérique Jacobs; Jeffrey Lipman
Vancomycin dosing in critically ill patients: robust methods for improved continuous-infusion regimens.
Antimicrobial agents and chemotherapy 2011;55(6):2704-9.
2011: Jason A Roberts; Andrea Kwa; Preecha Montakantikul; Charles Gomersall; Joseph L Kuti; David P Nicolau
Pharmacodynamic profiling of intravenous antibiotics against prevalent Gram-negative organisms across the globe: the PASSPORT Program-Asia-Pacific Region.
International journal of antimicrobial agents 2011;37(3):225-9.
2011: Marta Ulldemolins; Jason A Roberts; jordi rello; David L Paterson; Jeffrey Lipman
The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients.
Clinical pharmacokinetics 2011;50(2):99-110.
2011: Jason A Roberts; Carl M J Kirkpatrick; Jeffrey Lipman
Monte Carlo simulations: maximizing antibiotic pharmacokinetic data to optimize clinical practice for critically ill patients.
The Journal of antimicrobial chemotherapy 2011;66(2):227-31.
2011: Ruqaiya M Al Balushi; Merrilyn Banks; Jeremy Cohen; Joel Dulhunty; Jennifer D Paratz; Jason A Roberts; Jeffrey Lipman
Effect of intravenous GLutamine supplementation IN Trauma patients receiving enteral nutrition study protocol (GLINT Study): a prospective, blinded, randomised, placebo-controlled clinical trial.
BMJ open 2011;1(2):e000334.
2011: Alexandra Douglas; Mahdi Altukroni; Andrew A Udy; Michael S Roberts; Kersi Taraporewalla; Jason Jenkins; Jeffrey Lipman; Jason A Roberts
The pharmacokinetics of cefazolin in patients undergoing elective & semi-elective abdominal aortic aneurysm open repair surgery.
BMC anesthesiology 2011;11():5.
2011: Jason A Roberts; Michael S Roberts; Andrew Semark; Andrew A Udy; Carl Mj Kirkpatrick; David L Paterson; Matthew J Roberts; Peter Kruger; Jeffrey Lipman
Antibiotic dosing in the 'at risk' critically ill patient: Linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients.
BMC anesthesiology 2011;11():3.
2011: Julie M Varghese; Jason A Roberts; Jeffrey Lipman
Antimicrobial pharmacokinetic and pharmacodynamic issues in the critically ill with severe sepsis and septic shock.
Critical care clinics 2011;27(1):19-34.
2010: Jayesh Dhanani; Jason A Roberts; Michelle Chew; Jeffrey Lipman; Robert J Boots; David L Paterson; John F Fraser
Antimicrobial chemotherapy and lung microdialysis: a review.
International journal of antimicrobial agents 2010;36(6):491-500.
2010: Jason A Roberts; Marta Ulldemolins; Michael S Roberts; Brett McWhinney; Jacobus Ungerer; David L Paterson; Jeffrey Lipman
Therapeutic drug monitoring of beta-lactams in critically ill patients: proof of concept.
International journal of antimicrobial agents 2010;36(4):332-9.
2010: Jason A Roberts; Jonathan Field; Adam Visser; Rosemary Whitbread; Mandy Tallot; Jeffrey Lipman; Carl M J Kirkpatrick
Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury.
Antimicrobial agents and chemotherapy 2010;54(9):3635-40.
2010: Yoshiro Hayashi; Jason A Roberts; David L Paterson; Jeffrey Lipman
Pharmacokinetic evaluation of piperacillin-tazobactam.
Expert opinion on drug metabolism & toxicology 2010;6(8):1017-31.
2010: Marta Ulldemolins; Jason A Roberts; Steven C Wallis; jordi rello; Jeffrey Lipman
Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: special emphasis on unbound pharmacokinetics.
The Journal of antimicrobial chemotherapy 2010;65(8):1771-8.
2010: Julie M Varghese; Jason A Roberts; Jeffrey Lipman
Pharmacokinetics and pharmacodynamics in critically ill patients.
Current opinion in anaesthesiology 2010;23(4):472-8.
2010: I Bilgrami; Jason A Roberts; S C Wallis; J Thomas; J Davis; S Fowler; P B Goldrick; Jeffrey Lipman
Meropenem dosing in critically ill patients with sepsis receiving high-volume continuous venovenous hemofiltration.
Antimicrobial agents and chemotherapy 2010;54(7):2974-8.
2010: Andrew A Udy; Michael T Putt; Sulochana Shanmugathasan; Jason A Roberts; Jeffrey Lipman
Augmented renal clearance in the Intensive Care Unit: an illustrative case series.
International journal of antimicrobial agents 2010;35(6):606-8.
2010: Jason A Roberts; William W Hope; Jeffrey Lipman
Therapeutic drug monitoring of beta-lactams for critically ill patients: unwarranted or essential?
International journal of antimicrobial agents 2010;35(5):419-20.
2010: Jason A Roberts; Carl M J Kirkpatrick; Michael S Roberts; Andrew J Dalley; Jeffrey Lipman
First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis.
International journal of antimicrobial agents 2010;35(2):156-63.
2010: Andrew A Udy; Jason A Roberts; Robert J Boots; David L Paterson; Jeffrey Lipman
Augmented renal clearance: implications for antibacterial dosing in the critically ill.
Clinical pharmacokinetics 2010;49(1):1-16.
2009: Jason A Roberts; Carl M J Kirkpatrick; Michael S Roberts; Thomas A Robertson; Andrew J Dalley; Jeffrey Lipman
Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution.
The Journal of antimicrobial chemotherapy 2009;64(1):142-50.
2009: Jason A Roberts; Steven Webb; David Paterson; Kwok M Ho; Jeffrey Lipman
A systematic review on clinical benefits of continuous administration of beta-lactam antibiotics.
Critical care medicine 2009;37(6):2071-8.
2009: Jason A Roberts; Michael S Roberts; Thomas A Robertson; Andrew J Dalley; Jeffrey Lipman
Piperacillin penetration into tissue of critically ill patients with sepsis--bolus versus continuous administration?
Critical care medicine 2009;37(3):926-33.
2009: Jason A Roberts; Jeffrey Lipman
Pharmacokinetic issues for antibiotics in the critically ill patient.
Critical care medicine 2009;37(3):840-51; quiz 859.
2008: Jason A Roberts; Jeffrey Lipman; Stijn I Blot; jordi rello
Better outcomes through continuous infusion of time-dependent antibiotics to critically ill patients?
Current opinion in critical care 2008;14(4):390-6.
2008: Jason A Roberts; Peter Kruger; David L Paterson; Jeffrey Lipman
Antibiotic resistance--what's dosing got to do with it?
Critical care medicine 2008;36(8):2433-40.
2008: Jason A Roberts; Michael S Roberts; Thomas A Robertson; Sheree E Cross; Jeffrey Lipman
A novel way to investigate the effects of plasma exchange on antibiotic levels: use of microdialysis.
International journal of antimicrobial agents 2008;31(3):240-4.
2007: Jason A Roberts; Jeffrey Lipman
Optimizing use of beta-lactam antibiotics in the critically ill.
Seminars in respiratory and critical care medicine 2007;28(6):579-85.
2007: Jason A Roberts; Jennifer Paratz; Elizabeth Paratz; Wolfgang A Krueger; Jeffrey Lipman
Continuous infusion of beta-lactam antibiotics in severe infections: a review of its role.
International journal of antimicrobial agents 2007;30(1):11-8.
2006: Jason A Roberts; Jeffrey Lipman
Antibacterial dosing in intensive care: pharmacokinetics, degree of disease and pharmacodynamics of sepsis.
Clinical pharmacokinetics 2006;45(8):755-73.