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John Robinson

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Genes & Molecular Sequences

Amino Acid Sequence

Concepts & Ideas

Physiology

Molecular Mimicry

Chemicals & Drugs

Living Beings

Phenomena

Occupations

Drug Design

Procedures

Enzyme-Linked Immunosorbent Assay

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Co-Publications
Name
18
Moehle, Kerstin
11
Vrijbloed, Jan
10
Obrecht, Daniel
9
Pluschke, Gerd
8
Zurbriggen, Rinaldo
8
Zerbe, Katja
7
Mueller, Markus
6
Athanassiou, Zafiria
6
Dias, Ricardo
6
Varani, Gabriele
5
Vitali, Francesca
5
Woithe, Katharina
5
Li, Dong Bo
4
Okitsu, Shinji
4
Renard, Annabelle

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Publications

TOP 3
Davidson Amy; Leeper Thomas C; Athanassiou Zafiria; Patora-Komisarska Krystyna; Karn Jonathan; Robinson John A; Varani Gabriele
Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein.
Grässlin Anja; Amoreira Celine; Baldridge Kim K; Robinson John A
Thermodynamic and computational studies on the binding of p53-derived peptides and peptidomimetic inhibitors to HDM2.
Robinson John A
Design of protein-protein interaction inhibitors based on protein epitope mimetics.

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All Publications

2009: Davidson Amy; Leeper Thomas C; Athanassiou Zafiria; Patora-Komisarska Krystyna; Karn Jonathan; Robinson John A; Varani Gabriele
Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(29):11931-6.
2009: Grässlin Anja; Amoreira Celine; Baldridge Kim K; Robinson John A
Thermodynamic and computational studies on the binding of p53-derived peptides and peptidomimetic inhibitors to HDM2.
Chembiochem : a European journal of chemical biology 2009;10(8):1360-8.
2009: Robinson John A
Design of protein-protein interaction inhibitors based on protein epitope mimetics.
Chembiochem : a European journal of chemical biology 2009;10(6):971-3.
2009: Bardaro Michael F; Shajani Zahra; Patora-Komisarska Krystyna; Robinson John A; Varani Gabriele
How binding of small molecule and peptide ligands to HIV-1 TAR alters the RNA motional landscape.
Nucleic acids research 2009;37(5):1529-40.
2009: Li Dong Bo; Woithe Katharina; Geib Nina; Abou-Hadeed Khaled; Zerbe Katja; Robinson John A
Chapter 19. In vitro studies of phenol coupling enzymes involved in vancomycin biosynthesis.
Methods in enzymology 2009;458():487-509.
2008: Robinson John A; Demarco Steve; Gombert Frank; Moehle Kerstin; Obrecht Daniel
The design, structures and therapeutic potential of protein epitope mimetics.
Drug discovery today 2008;13(21-22):944-51.
2008: Woithe Katharina; Geib Nina; Meyer Odile; Wörtz Tanja; Zerbe Katja; Robinson John A
Exploring the substrate specificity of OxyB, a phenol coupling P450 enzyme involved in vancomycin biosynthesis.
Organic & biomolecular chemistry 2008;6(16):2861-7.
2008: Seitz Markus; Maillard Ludovic T; Obrecht Daniel; Robinson John A
Molecular characterization of the NCoA-1-STAT 6 interaction.
Chembiochem : a European journal of chemical biology 2008;9(8):1318-22.
2008: Geib Nina; Woithe Katharina; Zerbe Katja; Li Dong Bo; Robinson John A
New insights into the first oxidative phenol coupling reaction during vancomycin biosynthesis.
Bioorganic & medicinal chemistry letters 2008;18(10):3081-4.
2008: Okitsu Shinji L; Mueller Markus S; Amacker Mario; Vogel Denise; Westerfeld Nicole; Robinson John A; Zurbriggen Rinaldo; Pluschke Gerd
Preclinical profiling of the immunogenicity of a two-component subunit malaria vaccine candidate based on virosome technology.
Human vaccines 2008;4(2):106-14.
2007: Srinivas Nityakalyani; Moehle Kerstin; Abou-Hadeed Khaled; Obrecht Daniel; Robinson John A
Biaryl amino acid templates in place of D-Pro-L-Pro in cyclic beta-hairpin cationic antimicrobial peptidomimetics.
Organic & biomolecular chemistry 2007;5(19):3100-5.
2007: Okitsu Shinji L; Boato Francesca; Mueller Markus S; Li Dong Bo; Vogel Denise; Westerfeld Nicole; Zurbriggen Rinaldo; Robinson John A; Pluschke Gerd
Antibodies elicited by a virosomally formulated Plasmodium falciparum serine repeat antigen-5 derived peptide detect the processed 47 kDa fragment both in sporozoites and merozoites.
Peptides 2007;28(10):2051-60.
2007: Okitsu Shinji L; Kienzl Ursula; Moehle Kerstin; Silvie Olivier; Peduzzi Elisabetta; Mueller Markus S; Sauerwein Robert W; Matile Hugues; Zurbriggen Rinaldo; Mazier Dominique; Robinson John A; Pluschke Gerd
Structure-activity-based design of a synthetic malaria peptide eliciting sporozoite inhibitory antibodies in a virosomal formulation.
Chemistry & biology 2007;14(5):577-87.
2007: Woithe Katharina; Geib Nina; Zerbe Katja; Li Dong Bo; Heck Markus; Fournier-Rousset Severine; Meyer Odile; Vitali Francesca; Matoba Nobuatsu; Abou-Hadeed Khaled; Robinson John A
Oxidative phenol coupling reactions catalyzed by OxyB: a cytochrome P450 from the vancomycin producing organism. implications for vancomycin biosynthesis.
Journal of the American Chemical Society 2007;129(21):6887-95.
2007: Athanassiou Zafiria; Patora Krystyna; Dias Ricardo L A; Moehle Kerstin; Robinson John A; Varani Gabriele
Structure-guided peptidomimetic design leads to nanomolar beta-hairpin inhibitors of the Tat-TAR interaction of bovine immunodeficiency virus.
Biochemistry 2007;46(3):741-51.
2007: Okitsu Shinji L; Silvie Olivier; Westerfeld Nicole; Curcic Marija; Kammer Andreas R; Mueller Markus S; Sauerwein Robert W; Robinson John A; Genton Blaise; Mazier Dominique; Zurbriggen Rinaldo; Pluschke Gerd
A virosomal malaria peptide vaccine elicits a long-lasting sporozoite-inhibitory antibody response in a phase 1a clinical trial.
PloS one 2007;2(12):e1278.
2007: Boato Francesca; Thomas Richard M; Ghasparian Arin; Freund-Renard Annabelle; Moehle Kerstin; Robinson John A
Synthetic virus-like particles from self-assembling coiled-coil lipopeptides and their use in antigen display to the immune system.
Angewandte Chemie (International ed. in English) 2007;46(47):9015-8.
2007: Moehle Kerstin; Athanassiou Zafiria; Patora Krystyna; Davidson Amy; Varani Gabriele; Robinson John A
Design of beta-hairpin peptidomimetics that inhibit binding of alpha-helical HIV-1 Rev protein to the rev response element RNA.
Angewandte Chemie (International ed. in English) 2007;46(47):9101-4.
2006: James Sonya; Moehle Kerstin; Renard Annabelle; Mueller Markus S; Vogel Denise; Zurbriggen Rinaldo; Pluschke Gerd; Robinson John A
Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from Plasmodium falciparum merozoite surface protein-1.
Chembiochem : a European journal of chemical biology 2006;7(12):1943-50.
2006: DeMarco Steven J; Henze Heiko; Lederer Alexander; Moehle Kerstin; Mukherjee Reshmi; Romagnoli Barbara; Robinson John A; Brianza Federico; Gombert Frank O; Lociuro Sergio; Ludin Christian; Vrijbloed Jan Willem; Zumbrunn Jürg; Obrecht Jean-Pierre; Obrecht Daniel; Brondani Vincent; Hamy François; Klimkait Thomas
Discovery of novel, highly potent and selective beta-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles.
Bioorganic & medicinal chemistry 2006;14(24):8396-404.
2006: Fasan Rudi; Dias Ricardo L A; Moehle Kerstin; Zerbe Oliver; Obrecht Daniel; Mittl Peer R E; Grütter Markus G; Robinson John A
Structure-activity studies in a family of beta-hairpin protein epitope mimetic inhibitors of the p53-HDM2 protein-protein interaction.
Chembiochem : a European journal of chemical biology 2006;7(3):515-26.
2006: Dias Ricardo L A; Fasan Rudi; Moehle Kerstin; Renard Annabelle; Obrecht Daniel; Robinson John A
Protein ligand design: from phage display to synthetic protein epitope mimetics in human antibody Fc-binding peptidomimetics.
Journal of the American Chemical Society 2006;128(8):2726-32.
2006: Ghasparian Arin; Moehle Kerstin; Linden Anthony; Robinson John A
Crystal structure of an NPNA-repeat motif from the circumsporozoite protein of the malaria parasite Plasmodium falciparum.
Chemical communications (Cambridge, England) 2006;(2):174-6.
2005: Leeper Thomas C; Athanassiou Zafiria; Dias Ricardo L A; Robinson John A; Varani Gabriele
TAR RNA recognition by a cyclic peptidomimetic of Tat protein.
Biochemistry 2005;44(37):12362-72.
2005: Bo Li Dong; Robinson John A
An improved solid-phase methodology for the synthesis of putative hexa- and heptapeptide intermediates in vancomycin biosynthesis.
Organic & biomolecular chemistry 2005;3(7):1233-9.
2005: Robinson John A; Shankaramma Sasalu C; Jetter Peter; Kienzl Ursula; Schwendener Reto A; Vrijbloed Jan W; Obrecht Daniel
Properties and structure-activity studies of cyclic beta-hairpin peptidomimetics based on the cationic antimicrobial peptide protegrin I.
Bioorganic & medicinal chemistry 2005;13(6):2055-64.
2004: Zerbe Katja; Woithe Katharina; Li Dong Bo; Vitali Francesca; Bigler Laurent; Robinson John A
An oxidative phenol coupling reaction catalyzed by oxyB, a cytochrome P450 from the vancomycin-producing microorganism.
Angewandte Chemie (International ed. in English) 2004;43(48):6709-13.
2004: Athanassiou Zafiria; Dias Ricardo L A; Moehle Kerstin; Dobson Neil; Varani Gabriele; Robinson John A
Structural mimicry of retroviral tat proteins by constrained beta-hairpin peptidomimetics: ligands with high affinity and selectivity for viral TAR RNA regulatory elements.
Journal of the American Chemical Society 2004;126(22):6906-13.
2004: Fasan Rudi; Dias Ricardo L A; Moehle Kerstin; Zerbe Oliver; Vrijbloed Jan W; Obrecht Daniel; Robinson John A
Using a beta-hairpin to mimic an alpha-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction.
Angewandte Chemie (International ed. in English) 2004;43(16):2109-12.
2003: Vitali Francesca; Zerbe Katja; Robinson John A
Production of vancomycin aglycone conjugated to a peptide carrier domain derived from a biosynthetic non-ribosomal peptide synthetase.
Chemical communications (Cambridge, England) 2003;(21):2718-9.
2003: Pylypenko Olena; Vitali Francesca; Zerbe Katja; Robinson John A; Schlichting Ilme
Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis.
The Journal of biological chemistry 2003;278(47):46727-33.
2003: Shankaramma Sasalu C; Moehle Kerstin; James Sonya; Vrijbloed Jan W; Obrecht Daniel; Robinson John A
A family of macrocyclic antibiotics with a mixed peptide-peptoid beta-hairpin backbone conformation.
Chemical communications (Cambridge, England) 2003;(15):1842-3.
2003: Mueller Markus S; Renard Annabelle; Boato Francesca; Vogel Denise; Naegeli Martin; Zurbriggen Rinaldo; Robinson John A; Pluschke Gerd
Induction of parasite growth-inhibitory antibodies by a virosomal formulation of a peptidomimetic of loop I from domain III of Plasmodium falciparum apical membrane antigen 1.
Infection and immunity 2003;71(8):4749-58.
2003: Pfeiffer Bernhard; Peduzzi Elisabetta; Moehle Kerstin; Zurbriggen Rinaldo; Glück Reinhard; Pluschke Gerd; Robinson John A
A virosome-mimotope approach to synthetic vaccine design and optimization: synthesis, conformation, and immune recognition of a potential malaria-vaccine candidate.
Angewandte Chemie (International ed. in English) 2003;42(21):2368-71.
2003: Helg A; Mueller M S; Joss A; Pöltl-Frank F; Stuart F; Robinson J A; Pluschke G
Comparison of analytical methods for the evaluation of antibody responses against epitopes of polymorphic protein antigens.
Journal of immunological methods 2003;276(1-2):19-31.
2002: Zerbe Katja; Pylypenko Olena; Vitali Francesca; Zhang Weiwen; Rouset Severine; Heck Markus; Vrijbloed Jan W; Bischoff Daniel; Bister Bojan; Süssmuth Roderich D; Pelzer Stefan; Wohlleben Wolfgang; Robinson John A; Schlichting Ilme
Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.
The Journal of biological chemistry 2002;277(49):47476-85.
2002: Shankaramma Sasalu C; Athanassiou Zafiria; Zerbe Oliver; Moehle Kerstin; Mouton Carole; Bernardini Francesca; Vrijbloed Jan W; Obrecht Daniel; Robinson John A
Macrocyclic hairpin mimetics of the cationic antimicrobial peptide protegrin I: a new family of broad-spectrum antibiotics.
Chembiochem : a European journal of chemical biology 2002;3(11):1126-33.
2002: Descours Anne; Moehle Kerstin; Renard Annabelle; Robinson John A
A new family of beta-hairpin mimetics based on a trypsin inhibitor from sunflower seeds.
Chembiochem : a European journal of chemical biology 2002;3(4):318-23.
2001: Moreno R; Jiang L; Moehle K; Zurbriggen R; Glück R; Robinson J A; Pluschke G
Exploiting conformationally constrained peptidomimetics and an efficient human-compatible delivery system in synthetic vaccine design.
Chembiochem : a European journal of chemical biology 2001;2(11):838-43.
2000: Lang S; Xu J; Stuart F; Thomas R M; Vrijbloed J W; Robinson J A
Analysis of antibody A6 binding to the extracellular interferon gamma receptor alpha-chain by alanine-scanning mutagenesis and random mutagenesis with phage display.
Biochemistry 2000;39(51):15674-85.
1999: Ratnatilleke A; Vrijbloed J W; Robinson J A
Cloning and sequencing of the coenzyme B(12)-binding domain of isobutyryl-CoA mutase from Streptomyces cinnamonensis, reconstitution of mutase activity, and characterization of the recombinant enzyme produced in Escherichia coli.
The Journal of biological chemistry 1999;274(44):31679-85.
1999: Vrijbloed J W; Zerbe-Burkhardt K; Ratnatilleke A; Grubelnik-Leiser A; Robinson J A
Insertional inactivation of methylmalonyl coenzyme A (CoA) mutase and isobutyryl-CoA mutase genes in Streptomyces cinnamonensis: influence on polyketide antibiotic biosynthesis.
Journal of bacteriology 1999;181(18):5600-5.
1999: Hofstädter K; Stuart F; Jiang L; Vrijbloed J W; Robinson J A
On the importance of being aromatic at an antibody-protein antigen interface: mutagenesis of the extracellular interferon gamma receptor and recognition by the neutralizing antibody A6.
Journal of molecular biology 1999;285(2):805-15.
1998: Zerbe-Burkhardt K; Ratnatilleke A; Philippon N; Birch A; Leiser A; Vrijbloed J W; Hess D; Hunziker P; Robinson J A
Cloning, sequencing, expression, and insertional inactivation of the gene for the large subunit of the coenzyme B12-dependent isobutyryl-CoA mutase from Streptomyces cinnamonensis.
The Journal of biological chemistry 1998;273(11):6508-17.
1997: Sogabe S; Stuart F; Henke C; Bridges A; Williams G; Birch A; Winkler F K; Robinson J A
Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex.
Journal of molecular biology 1997;273(4):882-97.
1996: Leiser A; Birch A; Robinson J A
Cloning, sequencing, overexpression in Escherichia coli, and inactivation of the valine dehydrogenase gene in the polyether antibiotic producer Streptomyces cinnamonensis.
Gene 1996;177(1-2):217-22.
1996: Bridges A; Stuart F; Späth J; Lang S; Henke C; Birch A; Robinson J A
Production and characterization of anti-human interferon gamma receptor antibody fragments that inhibit cytokine binding to the receptor.
Protein engineering 1996;9(4):365-70.
1995: Bridges A; Birch A; Williams G; Aguet M; Schlatter D; Huber W; Garotta G; Robinson J A
Variable region cDNA sequences and characterization of murine anti-human interferon gamma receptor monoclonal antibodies that inhibit receptor binding by interferon gamma.
Molecular immunology 1995;32(17-18):1329-38.
1995: Ruegg N; Williams G; Birch A; Robinson J A; Schlatter D; Huber W
Mutagenesis of immunoglobulin-like domains from the extracellular human interferon-gamma receptor alpha chain and their recognition by neutralizing antibodies monitored by surface plasmon resonance technology.
Journal of immunological methods 1995;183(1):95-101.
1995: Williams G; Ruegg N; Birch A; Weber C; Hofstädter K; Robinson J A; Aguet M; Garotta G; Schlatter D; Huber W
Dissection of the extracellular human interferon gamma receptor alpha-chain into two immunoglobulin-like domains. Production in an Escherichia coli thioredoxin gene fusion expression system and recognition by neutralizing antibodies.
Biochemistry 1995;34(5):1787-97.
1995: Birch A W; Robinson J A
Polyethers.
Biotechnology (Reading, Mass.) 1995;28():443-76.
1993: Birch A; Leiser A; Robinson J A
Cloning, sequencing, and expression of the gene encoding methylmalonyl-coenzyme A mutase from Streptomyces cinnamonensis.
Journal of bacteriology 1993;175(11):3511-9.
1992: Patzelt H; Gaudet V; Robinson J A
Stimulation of polyether antibiotic production in streptomycetes by heptakis-2,6-di-O-methyl beta-cyclodextrin.
The Journal of antibiotics 1992;45(11):1806-8.
1992: Plater R; Robinson J A
Cloning and sequence of a gene encoding macrotetrolide antibiotic resistance from Streptomyces griseus.
Gene 1992;112(1):117-22.
1991: Robinson J A
Polyketide synthase complexes: their structure and function in antibiotic biosynthesis.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1991;332(1263):107-14.
1991: Robinson J A
Chemical and biochemical aspects of polyether-ionophore antibiotic biosynthesis.
Fortschritte der Chemie organischer Naturstoffe. Progress in the chemistry of organic natural products. Progrès dans la chimie des substances organiques naturelles 1991;58():1-81.

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