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DM Rock

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Concepts & Ideas

Structure-Activity Relationship

Physiology

Co-author Network

Publications

TOP 3
Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; K M Siebers; TC Malone; A Chatterjee; MR Feng; Susan M Lotarski; DM Rock; SJ Stoehr; Charles P Taylor; Mark L Weber; GP Miljanich; E Millerman; BG Szoke
Neuronal N-type calcium channel blockers: a series of 4-piperidinylaniline analogs with analgesic activity.
Todd R Ryder; Lain-Yen Hu; Michael F Rafferty; Susan M Lotarski; DM Rock; SJ Stoehr; Charles P Taylor; Mark L Weber; GP Miljanich; E Millerman; BG Szoke
Structure-activity relationship at the leucine side chain in a series of N,N-dialkyldipeptidyl-amines as N-type calcium channel blockers.
Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; MR Feng; Susan M Lotarski; DM Rock; M Sinz; SJ Stoehr; Charles P Taylor; Mark L Weber; SS Bowersox; GP Miljanich; E Millerman; Y X Wang; BG Szoke
Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.

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All Publications

2000: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; K M Siebers; TC Malone; A Chatterjee; MR Feng; Susan M Lotarski; DM Rock; SJ Stoehr; Charles P Taylor; Mark L Weber; GP Miljanich; E Millerman; BG Szoke
Neuronal N-type calcium channel blockers: a series of 4-piperidinylaniline analogs with analgesic activity.
Drug design and discovery 2000;17(1):85-93.
2000: Todd R Ryder; Lain-Yen Hu; Michael F Rafferty; Susan M Lotarski; DM Rock; SJ Stoehr; Charles P Taylor; Mark L Weber; GP Miljanich; E Millerman; BG Szoke
Structure-activity relationship at the leucine side chain in a series of N,N-dialkyldipeptidyl-amines as N-type calcium channel blockers.
Drug design and discovery 2000;16(4):317-22.
1999: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; MR Feng; Susan M Lotarski; DM Rock; M Sinz; SJ Stoehr; Charles P Taylor; Mark L Weber; SS Bowersox; GP Miljanich; E Millerman; Y X Wang; BG Szoke
Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.
Journal of medicinal chemistry 1999;42(20):4239-49.
1999: Todd R Ryder; Lain-Yen Hu; Michael F Rafferty; Susan M Lotarski; DM Rock; SJ Stoehr; Charles P Taylor; Mark L Weber; GP Miljanich; E Millerman; BG Szoke
Structure-activity relationship at the proximal phenyl group in a series of non-peptidyl N-type calcium channel antagonists.
Bioorganic & medicinal chemistry letters 1999;9(16):2453-8.
1999: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; David J Dooley; J J Geer; Susan M Lotarski; GP Miljanich; E Millerman; DM Rock; SJ Stoehr; BG Szoke; Charles P Taylor; Mark G Vartanian
Structure-activity relationship of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers.
Bioorganic & medicinal chemistry letters 1999;9(15):2151-6.
1999: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; Wayne L Cody; Susan M Lotarski; GP Miljanich; E Millerman; DM Rock; Yuntao Song; SJ Stoehr; Charles P Taylor; Mark L Weber; BG Szoke; Mark G Vartanian
N,N-dialkyl-dipeptidylamines as novel N-type calcium channel blockers.
Bioorganic & medicinal chemistry letters 1999;9(6):907-12.
1991: DM Rock; M J McLean; R L Macdonald; W A Catterall; Charles P Taylor
Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-alpha-benzoate binding in vitro.
Epilepsy research 1991;8(3):197-203.
1990: Peter A Boxer; J J Cordon; M E Mann; L C Rodolosi; Mark G Vartanian; DM Rock; Charles P Taylor; F W Marcoux
Comparison of phenytoin with noncompetitive N-methyl-D-aspartate antagonists in a model of focal brain ischemia in rat.
Stroke; a journal of cerebral circulation 1990;21(11 Suppl):III47-51.
1989: DM Rock; R L Macdonald; Charles P Taylor
Blockade of sustained repetitive action potentials in cultured spinal cord neurons by zonisamide (AD 810, CI 912), a novel anticonvulsant.
Epilepsy research 1989;3(2):138-43.
1986: DM Rock; Charles P Taylor
Effects of diazepam, pentobarbital, phenytoin and pentylenetetrazol on hippocampal paired-pulse inhibition in vivo.
Neuroscience letters 1986;65(3):265-70.