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Christian Bien

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Christian G Bien; Thomas Bast; Albert J Becker; Peter Herkenrath; Michael Karenfort; Bernd Kruse; Stefan Kuczaty; Gerhard Kurlemann; Sabine Rona; Robert Sassen; Susanne Schubert-Bast; Henning Tiemeier; Horst Urbach; Silvia Vieker; Stefan Vlaho; Marec von Lehe; Bernd Wilken; Christian E Elger
Rasmussen encephalitis: incidence and course under randomized therapy with tacrolimus or intravenous immunoglobulins.
Christian G Bien; Ingmar Blümcke; Francesc Graus; Kurt A Jellinger; Hans Lassmann; David E Reuss; Teresa Ribalta; Jürgen Schlegel; Ian Sutton; Angela Vincent; Michael H Barnett; Albert J Becker; Jan Bauer
Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis.
Jan Bauer; Annamaria Vezzani; Christian G Bien
Epileptic encephalitis: the role of the innate and adaptive immune system.

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All Publications

2013: Christian G Bien; Thomas Bast; Albert J Becker; Peter Herkenrath; Michael Karenfort; Bernd Kruse; Stefan Kuczaty; Gerhard Kurlemann; Sabine Rona; Robert Sassen; Susanne Schubert-Bast; Henning Tiemeier; Horst Urbach; Silvia Vieker; Stefan Vlaho; Marec von Lehe; Bernd Wilken; Christian E Elger
Rasmussen encephalitis: incidence and course under randomized therapy with tacrolimus or intravenous immunoglobulins.
Epilepsia 2013;54(3):543-50.
2012: Christian G Bien; Ingmar Blümcke; Francesc Graus; Kurt A Jellinger; Hans Lassmann; David E Reuss; Teresa Ribalta; Jürgen Schlegel; Ian Sutton; Angela Vincent; Michael H Barnett; Albert J Becker; Jan Bauer
Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis.
Brain : a journal of neurology 2012;135(Pt 5):1622-38.
2012: Jan Bauer; Annamaria Vezzani; Christian G Bien
Epileptic encephalitis: the role of the innate and adaptive immune system.
Brain pathology (Zurich, Switzerland) 2012;22(3):412-21.
2012: Jan Wagner; Christian G Bien; Christian E Elger; Jan-Christoph Schoene-Bake; Horst Urbach; Bernd Weber
Automated 3D MRI volumetry reveals regional atrophy differences in Rasmussen encephalitis.
Epilepsia 2012;53(4):613-21.
2011: Christoph Helmstaedter; Inga Petzold; Christian G Bien
The cognitive consequence of resecting nonlesional tissues in epilepsy surgery--results from MRI- and histopathology-negative patients with temporal lobe epilepsy.
Epilepsia 2011;52(8):1402-8.
2011: Anna Schönberger; Horst Urbach; Juri-A Witt; Albert J Becker; Christian G Bien; Christian E Elger; Eva Gembe; Alexander Grote; Pitt Niehusmann
Genetic analysis of tuberous-sclerosis genes 1 and 2 in nonlesional focal epilepsy.
Epilepsy & behavior : E&B 2011;21(3):233-7.
2011: Henriette J Tschampa; Susanne Greschus; Robert Sassen; Christian G Bien; Horst Urbach
Thalamus lesions in chronic and acute seizure disorders.
Neuroradiology 2011;53(4):245-54.
2011: Olaf E M G Schijns; Christian G Bien; Michael Majores; Marec von Lehe; Horst Urbach; Albert Becker; Johannes Schramm; Christian E Elger; Hans Clusmann
Presence of temporal gray-white matter abnormalities does not influence epilepsy surgery outcome in temporal lobe epilepsy with hippocampal sclerosis.
Neurosurgery 2011;68(1):98-106; discussion 107.
2011: Pitt Niehusmann; Rainer Surges; Randi D von Wrede; Christian E Elger; Jörg Wellmer; Jens Reimann; Horst Urbach; Stefan Vielhaber; Christian G Bien; Wolfram S Kunz
Mitochondrial dysfunction due to Leber's hereditary optic neuropathy as a cause of visual loss during assessment for epilepsy surgery.
Epilepsy & behavior : E&B 2011;20(1):38-43.
2010: Pitt Niehusmann; Tobias Mittelstaedt; Christian G Bien; Jan F Drexler; Alexander Grote; Susanne Schoch; Albert J Becker
Presence of human herpes virus 6 DNA exclusively in temporal lobe epilepsy brain tissue of patients with history of encephalitis.
Epilepsia 2010;51(12):2478-83.
2010: Georg Neuloh; Christian G Bien; Hans Clusmann; Marec von Lehe; Johannes Schramm
Continuous motor monitoring enhances functional preservation and seizure-free outcome in surgery for intractable focal epilepsy.
Acta neurochirurgica 2010;152(8):1307-14.
2010: Michael P Malter; Christoph Helmstaedter; Horst Urbach; Angela Vincent; Christian G Bien
Antibodies to glutamic acid decarboxylase define a form of limbic encephalitis.
Annals of neurology 2010;67(4):470-8.
2010: Eva Ludowig; Jürn Möller; Christian G Bien; Thomas F Münte; Christian E Elger; Timm Rosburg
Active suppression in the mediotemporal lobe during directed forgetting.
Neurobiology of learning and memory 2010;93(3):352-61.
2010: Eva Ludowig; Christian G Bien; Christian E Elger; Timm Rosburg
Two P300 generators in the hippocampal formation.
Hippocampus 2010;20(1):186-95.
2009: Christian G Bien; Miriam Szinay; Jan Wagner; Hans Clusmann; Albert J Becker; Horst Urbach
Characteristics and surgical outcomes of patients with refractory magnetic resonance imaging-negative epilepsies.
Archives of neurology 2009;66(12):1491-9.
2009: Jan Bauer; Christian G Bien
Encephalitis and epilepsy.
Seminars in immunopathology 2009;31(4):537-44.
2009: Christian G Bien; Johannes Schramm
Treatment of Rasmussen encephalitis half a century after its initial description: promising prospects and a dilemma.
Epilepsy research 2009;86(2-3):101-12.
2009: Bettina M Soeder; Ulrike Gleissner; Horst Urbach; Hans Clusmann; Christian E Elger; A Vincent; Christian G Bien
Causes, presentation and outcome of lesional adult onset mediotemporal lobe epilepsy.
Journal of neurology, neurosurgery, and psychiatry 2009;80(8):894-9.
2009: Devin K Binder; Martin Podlogar; Hans Clusmann; Christian G Bien; Horst Urbach; Johannes Schramm; Thomas Kral
Surgical treatment of parietal lobe epilepsy.
Journal of neurosurgery 2009;110(6):1170-8.
2009: Pitt Niehusmann; Josep Dalmau; Christian Rudlowski; Angela Vincent; Christian E Elger; Jeffrey E Rossi; Christian G Bien
Diagnostic value of N-methyl-D-aspartate receptor antibodies in women with new-onset epilepsy.
Archives of neurology 2009;66(4):458-64.
2009: Judith Kröll-Seger; Christian G Bien; Hans-Jürgen Huppertz
Non-paraneoplastic limbic encephalitis associated with antibodies to potassium channels leading to bilateral hippocampal sclerosis in a pre-pubertal girl.
Epileptic disorders : international epilepsy journal with videotape 2009;11(1):54-9.
2009: Jan Wagner; Christian E Elger; Horst Urbach; Christian G Bien
Electric stimulation of periventricular heterotopia: participation in higher cerebral functions.
Epilepsy & behavior : E&B 2009;14(2):425-8.
2008: Devin K Binder; Marec von Lehe; Thomas Kral; Christian G Bien; Horst Urbach; Johannes Schramm; Hans Clusmann
Surgical treatment of occipital lobe epilepsy.
Journal of neurosurgery 2008;109(1):57-69.
2008: Timm Rosburg; Peter Trautner; Eva Ludowig; Christoph Helmstaedter; Christian G Bien; Christian E Elger; Nashaat N Boutros
Sensory gating in epilepsy - effects of the lateralization of hippocampal sclerosis.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2008;119(6):1310-9.
2008: Eva Ludowig; Peter Trautner; Martin Kurthen; Carlo Schaller; Christian G Bien; Christian E Elger; Timm Rosburg
Intracranially recorded memory-related potentials reveal higher posterior than anterior hippocampal involvement in verbal encoding and retrieval.
Journal of cognitive neuroscience 2008;20(5):841-51.
2008: Christian G Bien; Christian E Elger
Epilepsia partialis continua: semiology and differential diagnoses.
Epileptic disorders : international epilepsy journal with videotape 2008;10(1):3-7.
2008: Howan Leung; Kaspar Schindler; Hans Clusmann; Christian G Bien; Annkathrin Pöpel; Johannes Schramm; Patrick Kwan; Lawrence K S Wong; Christian E Elger
Mesial frontal epilepsy and ictal body turning along the horizontal body axis.
Archives of neurology 2008;65(1):71-7.
2008: Bernd Wilken; M Baumann; Christian G Bien; B Hero; Kevin Rostasy; F Hanefeld
Chronic relapsing opsoclonus-myoclonus syndrome: combination of cyclophosphamide and dexamethasone pulses.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 2008;12(1):51-5.
2007: Annkathrin Poepel; Sven Jarius; Lukas Heukamp; Horst Urbach; Christian E Elger; Christian G Bien; Raymond Voltz
Neurological course of long-term surviving patients with SCLC and anti-Hu syndrome.
Journal of the neurological sciences 2007;263(1-2):145-8.
2007: Horst Urbach; Devin Binder; Marec von Lehe; Martin Podlogar; Christian G Bien; Albert Becker; Johannes Schramm; Thomas Kral; Hans Clusmann
Correlation of MRI and histopathology in epileptogenic parietal and occipital lobe lesions.
Seizure : the journal of the British Epilepsy Association 2007;16(7):608-14.
2007: Christian G Bien; Horst Urbach; Johannes Schramm; Bettina M Soeder; A J Becker; Raymond Voltz; A Vincent; Christian E Elger
Limbic encephalitis as a precipitating event in adult-onset temporal lobe epilepsy.
Neurology 2007;69(12):1236-44.
2007: Jan Bauer; Christian E Elger; Volkmar H Hans; Johannes Schramm; Horst Urbach; Hans Lassmann; Christian G Bien
Astrocytes are a specific immunological target in Rasmussen's encephalitis.
Annals of neurology 2007;62(1):67-80.
2007: Anne Kirchner; Annkathrin Poepel; Matthias Hantsch; Horst Urbach; Christian E Elger; Christian G Bien
Spinal algetic-tonic seizures manifesting as paroxysmal "positive" Brown-Séquard syndrome.
Epileptic disorders : international epilepsy journal with videotape 2007;9(2):182-5.
2007: Christian G Bien; Christian E Elger
Limbic encephalitis: a cause of temporal lobe epilepsy with onset in adult life.
Epilepsy & behavior : E&B 2007;10(4):529-38.
2007: Christian G Bien; Christian E Elger; Y Leitner; M Gomori; B Ran; Horst Urbach; Bernd Wilken; isabelle korn-lubetzki
Slowly progressive hemiparesis in childhood as a consequence of Rasmussen encephalitis without or with delayed-onset seizures.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2007;14(4):387-90.
2006: Christian G Bien; Andreas Schulze-Bonhage; Bettina M Soeder; Johannes Schramm; Christian E Elger; Henning Tiemeier
Assessment of the long-term effects of epilepsy surgery with three different reference groups.
Epilepsia 2006;47(11):1865-9.
2006: M Nelles; Christian G Bien; Martin Kurthen; Marcus von Falkenhausen; Horst Urbach
Transient splenium lesions in presurgical epilepsy patients: incidence and pathogenesis.
Neuroradiology 2006;48(7):443-8.
2006: Horst Urbach; Bettina M Soeder; Monika Jeub; Thomas Klockgether; Bernhard Meyer; Christian G Bien
Serial MRI of limbic encephalitis.
Neuroradiology 2006;48(6):380-6.
2005: Christian G Bien; Christian E Elger
[Recent insights into Rasmussen encephalitis].
Der Nervenarzt 2005;76(12):1470, 1472-4, 1477-80, 1484-7.
2005: Thomas Dietl; Christian G Bien; Horst Urbach; Christian Elger; Martin Kurthen
Episodic depersonalization in focal epilepsy.
Epilepsy & behavior : E&B 2005;7(2):311-5.
2005: Bettina M Soeder; Horst Urbach; Christian E Elger; Christian G Bien; Stefan Beyenburg
[VGKC antibodies associated with limbic encephalitis].
Der Nervenarzt 2005;76(6):760-2.
2005: Sergey Larionov; Roy König; Horst Urbach; Robert Sassen; Christian E Elger; Christian G Bien
MRI brain volumetry in Rasmussen encephalitis: the fate of affected and "unaffected" hemispheres.
Neurology 2005;64(5):885-7.
2005: Christian G Bien; Tiziana Granata; Carlo Antozzi; J H Cross; O Dulac; Martin Kurthen; Hans Lassmann; Renato Mantegazza; J-G Villemure; Roberto Spreafico; Christian E Elger
Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: a European consensus statement.
Brain : a journal of neurology 2005;128(Pt 3):454-71.
2005: Christian G Bien; Jan Bauer
T-cells in human encephalitis.
Neuromolecular medicine 2005;7(3):243-53.
2004: Christian G Bien; Ulrike Gleissner; Robert Sassen; Guido Widman; Horst Urbach; Christian E Elger
An open study of tacrolimus therapy in Rasmussen encephalitis.
Neurology 2004;62(11):2106-9.
2004: isabelle korn-lubetzki; Christian G Bien; Jan Bauer; M Gomori; Heinz Wiendl; L Trajo; H Ovadia; Bernd Wilken; Volkmar H Hans; C E Elger; Haggit Hurvitz; Israel Steiner
Rasmussen encephalitis with active inflammation and delayed seizures onset.
Neurology 2004;62(6):984-6.
2002: Christian G Bien; Guido Widman; Horst Urbach; Robert Sassen; Stefan Kuczaty; Otmar D Wiestler; Johannes Schramm; Christian E Elger
The natural history of Rasmussen's encephalitis.
Brain : a journal of neurology 2002;125(Pt 8):1751-9.
2002: Christian G Bien; Christian E Elger; Heinz Wiendl
Advances in pathogenic concepts and therapeutic agents in Rasmussen's encephalitis.
Expert opinion on investigational drugs 2002;11(7):981-9.
2002: Christian G Bien; Jan Bauer; Thomas L Deckwerth; Heinz Wiendl; Martina Deckert; Otmar D Wiestler; Johannes Schramm; Christian E Elger; Hans Lassmann
Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis.
Annals of neurology 2002;51(3):311-8.
2002: Christian G Bien; Horst Urbach; Martina Deckert; Johannes Schramm; Otmar D Wiestler; Hans Lassmann; Christian E Elger
Diagnosis and staging of Rasmussen's encephalitis by serial MRI and histopathology.
Neurology 2002;58(2):250-7.
2001: Christian G Bien; Martin Kurthen; K Baron; Silke Lux; Christoph Helmstaedter; Johannes Schramm; Christian E Elger
Long-term seizure outcome and antiepileptic drug treatment in surgically treated temporal lobe epilepsy patients: a controlled study.
Epilepsia 2001;42(11):1416-21.
2001: Heinz Wiendl; Christian G Bien; P Bernasconi; B Fleckenstein; C E Elger; Johannes Dichgans; Renato Mantegazza; Arthur Melms
GluR3 antibodies: prevalence in focal epilepsy but no specificity for Rasmussen's encephalitis.
Neurology 2001;57(8):1511-4.
2000: Christian G Bien; Andreas Schulze-Bonhage; Martina Deckert; Horst Urbach; Christoph Helmstaedter; Thomas Grunwald; Carlo Schaller; Christian E Elger
Limbic encephalitis not associated with neoplasm as a cause of temporal lobe epilepsy.
Neurology 2000;55(12):1823-8.
2000: Christian G Bien; Felix Benninger; Horst Urbach; Johannes Schramm; Martin Kurthen; Christian E Elger
Localizing value of epileptic visual auras.
Brain : a journal of neurology 2000;123 ( Pt 2)():244-53.
1998: Christian G Bien
[The "break" in Aristotle's presentation of genetic contributions of man and woman. Or: must he, who says a, always say b?].
Medizinhistorisches Journal 1998;33(1):3-17.