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Esteban Rodríguez

Research Profile

Anatomy

Living Beings

Procedures

Chemicals & Drugs

Disorders

Hydrocephalus

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Ruth Roales-Buján; Esteban M Rodríguez; Sara Rodríguez; Luis-Manuel Rodríguez-Pérez; Karin Vío; María-Dolores Domínguez-Pinos; María García-Bonilla; Montserrat Guerra; Ailec Ho-Plagaro; Patricia Páez; José-Manuel Pérez-Fígares; Antonio J Jiménez
Astrocytes acquire morphological and functional characteristics of ependymal cells following disruption of ependyma in hydrocephalus.
Esteban M Rodríguez; Sara Rodríguez; Deborah A Sival; Karin Vío; Wilfred F A den Dunnen; James P McAllister; RI Muñoz; Eduardo Ortega; Alexander Ortloff; José-Manuel Pérez-Fígares; Luis Federico Batiz; María D Domínguez-Pinos; César González; Francisco Guerra; María M Guerra; Jaime Jaque; María C Jara; Antonio J Jiménez; Conrad Johanson
A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus.
Luis Federico Batiz; Antonio J Jiménez; Montserrat Guerra; Luis Manuel Rodríguez-Pérez; César D Toledo; Karin Vio; Patricia Páez; José-Manuel Pérez-Fígares; Esteban M Rodríguez
New ependymal cells are born postnatally in two discrete regions of the mouse brain and support ventricular enlargement in hydrocephalus.

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All Publications

2012: Ruth Roales-Buján; Esteban M Rodríguez; Sara Rodríguez; Luis-Manuel Rodríguez-Pérez; Karin Vío; María-Dolores Domínguez-Pinos; María García-Bonilla; Montserrat Guerra; Ailec Ho-Plagaro; Patricia Páez; José-Manuel Pérez-Fígares; Antonio J Jiménez
Astrocytes acquire morphological and functional characteristics of ependymal cells following disruption of ependyma in hydrocephalus.
Acta neuropathologica 2012;124(4):531-46.
2012: Esteban M Rodríguez; Sara Rodríguez; Deborah A Sival; Karin Vío; Wilfred F A den Dunnen; James P McAllister; RI Muñoz; Eduardo Ortega; Alexander Ortloff; José-Manuel Pérez-Fígares; Luis Federico Batiz; María D Domínguez-Pinos; César González; Francisco Guerra; María M Guerra; Jaime Jaque; María C Jara; Antonio J Jiménez; Conrad Johanson
A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus.
Biological research 2012;45(3):231-42.
2011: Luis Federico Batiz; Antonio J Jiménez; Montserrat Guerra; Luis Manuel Rodríguez-Pérez; César D Toledo; Karin Vio; Patricia Páez; José-Manuel Pérez-Fígares; Esteban M Rodríguez
New ependymal cells are born postnatally in two discrete regions of the mouse brain and support ventricular enlargement in hydrocephalus.
Acta neuropathologica 2011;121(6):721-35.
2011: Deborah A Sival; Montserrat Guerra; Wilfred F A den Dunnen; Luis Federico Batiz; Genaro Alvial; Agustín Castañeyra-Perdomo; Esteban M Rodríguez
Neuroependymal denudation is in progress in full-term human foetal spina bifida aperta.
Brain pathology (Zurich, Switzerland) 2011;21(2):163-79.
2010: Esteban M Rodríguez; Juan L Blázquez; Montserrat Guerra
The design of barriers in the hypothalamus allows the median eminence and the arcuate nucleus to enjoy private milieus: the former opens to the portal blood and the latter to the cerebrospinal fluid.
Peptides 2010;31(4):757-76.
2010: Montserrat Guerra; Juan Luis Blázquez; Bruno Peruzzo; Belén Peláez; Sara Rodríguez; Daniel Toranzo; Francisco Efrén Pastor; Esteban M Rodríguez
Cell organization of the rat pars tuberalis. Evidence for open communication between pars tuberalis cells, cerebrospinal fluid and tanycytes.
Cell and tissue research 2010;339(2):359-81.
2009: Antonio J Jiménez; José Manuel García-Verdugo; César Aliro González; Luis Federico Batiz; Luis Manuel Rodríguez-Pérez; Patricia Páez; Mario Soriano-Navarro; Ruth Roales-Buján; Patricia Rivera; Sara Rodríguez; Esteban M Rodríguez; José-Manuel Pérez-Fígares
Disruption of the neurogenic niche in the subventricular zone of postnatal hydrocephalic hyh mice.
Journal of neuropathology and experimental neurology 2009;68(9):1006-20.
2009: María Montserrat Guerra; Esteban M Rodríguez
Expression of tuberalin II, alpha-subunit of glycoprotein hormones and beta-thyrotropin hormone in the pars tuberalis of the rat: immunocytochemical evidence for pars tuberalis-specific cell types.
Neuroendocrinology 2009;90(3):269-82.
2009: Luis Federico Batiz; Gerardo A De Blas; Marcela A Michaut; Alfredo R Ramírez; Facundo Rodríguez; Marcelo H Ratto; Cristian Oliver; Claudia Tomes; Esteban M Rodríguez; Luis S Mayorga
Sperm from hyh mice carrying a point mutation in alphaSNAP have a defect in acrosome reaction.
PloS one 2009;4(3):e4963.
2008: Karin Vio; Sara Rodríguez; Carlos R Yulis; Cristian Oliver; Esteban M Rodríguez
The subcommissural organ of the rat secretes Reissner's fiber glycoproteins and CSF-soluble proteins reaching the internal and external CSF compartments.
Cerebrospinal fluid research 2008;5():3.
2007: Patricia Páez; Luis Federico Batiz; Ruth Roales-Buján; Luis-Manuel Rodríguez-Pérez; Sara Rodríguez; Antonio J Jiménez; Esteban M Rodríguez; José-Manuel Pérez-Fígares
Patterned neuropathologic events occurring in hyh congenital hydrocephalic mutant mice.
Journal of neuropathology and experimental neurology 2007;66(12):1082-92.
2006: Luis Federico Batiz; Patricia Páez; Antonio J Jiménez; Sara Rodríguez; Carolina Wagner; José-Manuel Pérez-Fígares; Esteban M Rodríguez
Heterogeneous expression of hydrocephalic phenotype in the hyh mice carrying a point mutation in alpha-SNAP.
Neurobiology of disease 2006;23(1):152-68.
2005: Juan Krsulovic; Bruno Peruzzo; Genaro Alvial; Carlos R Yulis; Esteban M Rodríguez
The destination of the aged, nonreleasable neurohypophyseal peptides stored in the neural lobe is associated to the remodeling of the neurosecretory axon.
Microscopy research and technique 2005;68(6):347-59.
2005: María Dolores Domínguez-Pinos; Patricia Páez; Antonio J Jiménez; Bernardo Weil; Miguel-Angel Arráez; José-Manuel Pérez-Fígares; Esteban M Rodríguez
Ependymal denudation and alterations of the subventricular zone occur in human fetuses with a moderate communicating hydrocephalus.
Journal of neuropathology and experimental neurology 2005;64(7):595-604.
2005: Hernán Montecinos; H Richter; Teresa Caprile; Esteban M Rodríguez
Synthesis of transthyretin by the ependymal cells of the subcommissural organ.
Cell and tissue research 2005;320(3):487-99.
2005: Esteban M Rodríguez; Juan Luis Blázquez; Francisco Efrén Pastor; Belén Peláez; Patricio Peña; Bruno Peruzzo; Pedro Amat
Hypothalamic tanycytes: a key component of brain-endocrine interaction.
International review of cytology 2005;247():89-164.
2004: Hans G Richter; Mercedes Tomé; Carlos R Yulis; Karin J Vío; Antonio J Jiménez; José-Manuel Pérez-Fígares; Esteban M Rodríguez
Transcription of SCO-spondin in the subcommissural organ: evidence for down-regulation mediated by serotonin.
Brain research. Molecular brain research 2004;129(1-2):151-62.
2004: Bruno Peruzzo; Francisco Efrén Pastor; Juan Luis Blázquez; Pedro Amat; Esteban M Rodríguez
Polarized endocytosis and transcytosis in the hypothalamic tanycytes of the rat.
Cell and tissue research 2004;317(2):147-64.
2004: Mercedes Tomé; Antonio J Jiménez; Hans Richter; Karin Vio; Francisco Javier Bermúdez-Silva; Esteban M Rodríguez; José-Manuel Pérez-Fígares
The subcommissural organ expresses D2, D3, D4, and D5 dopamine receptors.
Cell and tissue research 2004;317(1):65-77.
2003: Carolina Wagner; Luis Federico Batiz; Sara Rodríguez; Antonio J Jiménez; Patricia Páez; Mercedes Tomé; José-Manuel Pérez-Fígares; Esteban M Rodríguez
Cellular mechanisms involved in the stenosis and obliteration of the cerebral aqueduct of hyh mutant mice developing congenital hydrocephalus.
Journal of neuropathology and experimental neurology 2003;62(10):1019-40.
2002: Juan Luis Blázquez; Montserrat Guerra; Francisco Efrén Pastor; Bruno Peruzzo; Pedro Amat; Esteban M Rodríguez
Antibodies obtained by xenotransplantation of organ-cultured median eminence specifically recognize hypothalamic tanycytes.
Cell and tissue research 2002;308(2):241-53.
2002: María F Guiñazú; Hans G Richter; Esteban M Rodríguez
Bovine floor plate explants secrete SCO-spondin.
Cell and tissue research 2002;308(2):177-91.
2001: Antonio J Jiménez; Mercedes Tomé; Patricia Páez; Carolina Wagner; Sara Rodríguez; Pedro Fernández-Llebrez; Esteban M Rodríguez; José-Manuel Pérez-Fígares
A programmed ependymal denudation precedes congenital hydrocephalus in the hyh mutant mouse.
Journal of neuropathology and experimental neurology 2001;60(11):1105-19.
2001: Hans G Richter; RI Muñoz; C S Millán; M F Guiñazú; Carlos R Yulis; Esteban M Rodríguez
The floor plate cells from bovines express the mRNA encoding for SCO-spondin and its translation products.
Brain research. Molecular brain research 2001;93(2):137-47.
2001: M A del Brio; P Riera; Bruno Peruzzo; Esteban M Rodríguez
Hindbrain floor plate of the rat: ultrastructural changes occurring during development.
Microscopy research and technique 2001;52(5):615-26.
2001: José-Manuel Pérez-Fígares; A J Jimenez; Esteban M Rodríguez
Subcommissural organ, cerebrospinal fluid circulation, and hydrocephalus.
Microscopy research and technique 2001;52(5):591-607.
2001: Esteban M Rodríguez; A Oksche; Hernán Montecinos
Human subcommissural organ, with particular emphasis on its secretory activity during the fetal life.
Microscopy research and technique 2001;52(5):573-90.
2001: Benedicto Molina; Esteban M Rodríguez; Bruno Peruzzo; Teresa Caprile; Francisco Nualart
Spatial distribution of Reissner's fiber glycoproteins in the filum terminale of the rat and rabbit.
Microscopy research and technique 2001;52(5):552-63.
2001: E Miranda; J A Almonacid; S Rodriguez; J Perez; S Hein; M Cifuentes; Pedro Fernández-Llebrez; Esteban M Rodríguez
Searching for specific binding sites of the secretory glycoproteins of the subcommissural organ.
Microscopy research and technique 2001;52(5):541-51.
2001: K Schöbitz; C Gonzalez; Bruno Peruzzo; Carlos R Yulis; Esteban M Rodríguez
Organ culture of the bovine subcommissural organ: evidence for synthesis and release of the secretory material.
Microscopy research and technique 2001;52(5):496-509.
2000: Karin Vio; Sara Rodríguez; EH Navarrete; José-Manuel Pérez-Fígares; Antonio J Jiménez; Esteban M Rodríguez
Hydrocephalus induced by immunological blockage of the subcommissural organ-Reissner's fiber (RF) complex by maternal transfer of anti-RF antibodies.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2000;135(1):41-52.
2000: M A del Brío; P Riera; RI Muñoz; Hernán Montecinos; Esteban M Rodríguez
The metencephalic floor plate of chick embryos expresses two secretory glycoproteins homologous with the two glycoproteins secreted by the subcommissural organ.
Histochemistry and cell biology 2000;113(6):415-26.
2000: Bruno Peruzzo; Francisco Efrén Pastor; Juan Luis Blázquez; K Schöbitz; Belén Peláez; Pedro Amat; Esteban M Rodríguez
A second look at the barriers of the medial basal hypothalamus.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2000;132(1):10-26.
1999: Sara Rodríguez; Karin Vio; Carolina Wagner; M Barría; EH Navarrete; V D Ramírez; José-Manuel Pérez-Fígares; Esteban M Rodríguez
Changes in the cerebrospinal-fluid monoamines in rats with an immunoneutralization of the subcommissural organ-Reissner's fiber complex by maternal delivery of antibodies.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1999;128(3):278-90.
1999: Sara Rodríguez; EH Navarrete; Karin Vio; C González; K Schöbitz; Esteban M Rodríguez
Isograft and xenograft of the subcommissural organ into the lateral ventricle of the rat and the formation of Reissner's fiber.
Cell and tissue research 1999;296(3):457-69.
1999: C A González; Gladys Garcés; J C Sáez; K Schöbitz; Esteban M Rodríguez
The ependymocytes of the bovine subcommissural organ are functionally coupled through gap junctions.
Neuroscience letters 1999;262(3):175-8.
1998: Francisco Nualart; Silvia Hein; Carlos R Yulis; A M Zárraga; A Araya; Esteban M Rodríguez
Partial sequencing of Reissner's fiber glycoprotein I (RF-Gly I).
Cell and tissue research 1998;292(2):239-50.
1998: Esteban M Rodríguez; Sara Rodríguez; Silvia Hein
The subcommissural organ.
Microscopy research and technique 1998;41(2):98-123.
1998: JM Grondona; M Pérez-Martín; M Cifuentes; Juan Pérez; Guillermo Estivill-Torrús; José-Manuel Pérez-Fígares; Pedro Fernández-Llebrez; Esteban M Rodríguez
Neuraminidase injected into the cerebrospinal fluid impairs the assembly of the glycoproteins secreted by the subcommissural organ preventing the formation of Reissner's fiber.
Histochemistry and cell biology 1998;109(4):391-8.
1998: Carlos R Yulis; M D Mota; José A Andrades; Sara Rodríguez; Bruno Peruzzo; J M Mancera; Pablo Antonio Ramirez; M Garrido; J M Pérez-Fígarez; Pedro Fernández-Llebrez; Esteban M Rodríguez
Floor plate and the subcommissural organ are the source of secretory compounds of related nature: comparative immunocytochemical study.
The Journal of comparative neurology 1998;392(1):19-34.
1998: José-Manuel Pérez-Fígares; Antonio J Jiménez; M Pérez-Martín; Pedro Fernández-Llebrez; M Cifuentes; P Riera; Sara Rodríguez; Esteban M Rodríguez
Spontaneous congenital hydrocephalus in the mutant mouse hyh. Changes in the ventricular system and the subcommissural organ.
Journal of neuropathology and experimental neurology 1998;57(2):188-202.
1996: Juan Pérez; O Garrido; M Cifuentes; F J Alonso; Guillermo Estivill-Torrús; G Eller; F Nualart; M D López-Avalos; Pedro Fernández-Llebrez; Esteban M Rodríguez
Bovine Reissner's fiber (RF) and the central canal of the spinal cord: an immunocytochemical study using a set of monoclonal antibodies against the RF-glycoproteins.
Cell and tissue research 1996;286(1):33-42.
1996: F Nualart; Esteban M Rodríguez
Immunochemical analysis of the subcommissural organ-Reissner's fiber complex using antibodies against alkylated and deglycosylated glycoproteins of the bovine Reissner's fiber.
Cell and tissue research 1996;286(1):23-31.
1996: P Meurling; Esteban M Rodríguez; P Peña; JM Grondona; Juan Pérez
Hypophysial and extrahypophysial projections of the neurosecretory system of cartilaginous fishes: an immunocytochemical study using a polyclonal antibody against dogfish neurophysin.
The Journal of comparative neurology 1996;373(3):400-21.
1996: Pedro Fernández-Llebrez; M D López-Avalos; M D Mota; M Cifuentes; José A Andrades; JM Grondona; Juan Pérez; J M Pérez-Figares; Esteban M Rodríguez
Secretory glycoproteins of the roof and floor plates and their rostral derivatives, the subcommissural and flexural organs, in the developing central nervous system of vertebrates. An immunocytochemical study.
The International journal of developmental biology 1996;Suppl 1():151S-152S.
1995: M Cifuentes; Esteban M Rodríguez; S Hernández; Juan Pérez; B Peruzzo; Pedro Fernández-Llebrez
Antibody-mediated lysis of the bovine subcommissural organ maintained in culture.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1995;107(1):39-51.
1994: JM Grondona; Juan Pérez; M Cifuentes; M D López-Avalos; F J Nualart; B Peruzzo; Pedro Fernández-Llebrez; Esteban M Rodríguez
Analysis of the secretory glycoproteins of the subcommissural organ of the dogfish (Scyliorhinus canicula).
Brain research. Molecular brain research 1994;26(1-2):299-308.
1994: M Cifuentes; Sara Rodríguez; Juan Pérez; JM Grondona; Esteban M Rodríguez; Pedro Fernández-Llebrez
Decreased cerebrospinal fluid flow through the central canal of the spinal cord of rats immunologically deprived of Reissner's fibre.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1994;98(3):431-40.
1992: M Cifuentes; Pedro Fernández-Llebrez; Juan Pérez; José-Manuel Pérez-Fígares; Esteban M Rodríguez
Distribution of intraventricularly injected horseradish peroxidase in cerebrospinal fluid compartments of the rat spinal cord.
Cell and tissue research 1992;270(3):485-94.
1992: Esteban M Rodríguez; A Oksche; Silvia Hein; Carlos R Yulis
Cell biology of the subcommissural organ.
International review of cytology 1992;135():39-121.
1991: F Nualart; Silvia Hein; Esteban M Rodríguez; A Oksche
Identification and partial characterization of the secretory glycoproteins of the bovine subcommissural organ-Reissner's fiber complex. Evidence for the existence of two precursor forms.
Brain research. Molecular brain research 1991;11(3-4):227-38.
1990: Esteban M Rodríguez; O Garrido; A Oksche
Lectin histochemistry of the human fetal subcommissural organ.
Cell and tissue research 1990;262(1):105-13.
1990: Sara Rodríguez; Esteban M Rodríguez; P Jara; B Peruzzo; A Oksche
Single injection into the cerebrospinal fluid of antibodies against the secretory material of the subcommissural organ reversibly blocks formation of Reissner's fiber: immunocytochemical investigations in the rat.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1990;81(1):113-24.
1990: H Herrera; Esteban M Rodríguez
Secretory glycoproteins of the rat subcommissural organ are N-linked complex-type glycoproteins. Demonstration by combined use of lectins and specific glycosidases, and by the administration of Tunicamycin.
Histochemistry 1990;93(6):607-15.
1990: B Peruzzo; Juan Pérez; Pedro Fernández-Llebrez; José-Manuel Pérez-Fígares; Esteban M Rodríguez; A Oksche
Ultrastructural immunocytochemistry and lectin histochemistry of the subcommissural organ in the snake Natrix maura with particular emphasis on its vascular and leptomeningeal projections.
Histochemistry 1990;93(3):269-77.
1990: Esteban M Rodríguez; A Oksche; Sara Rodríguez; F Nualart; C Irigoin; Pedro Fernández-Llebrez; J M Pérez-Figares
Subcommissural organ and cerebrospinal fluid: a biochemical and experimental study.
Progress in clinical and biological research 1990;342():282-92.
1990: C Irigoin; Esteban M Rodríguez; M Heinrichs; K Frese; Sibylle Herzog; A Oksche; R Rott
Immunocytochemical study of the subcommissural organ of rats with induced postnatal hydrocephalus.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1990;82(2):384-92.
1989: Esteban M Rodríguez; Sara Rodríguez; K Schoebitz; Carlos R Yulis; P Hoffmann; V Manns; A Oksche
Light- and electron-microscopic investigation of the rat subcommissural organ grafted under the kidney capsule, with particular reference to immunocytochemistry and lectin histochemistry.
Cell and tissue research 1989;258(3):499-514.
1989: B Peruzzo; Esteban M Rodríguez
Light and electron microscopical demonstration of concanavalin A and wheat-germ agglutinin binding sites by use of antibodies against the lectin or its label (peroxidase).
Histochemistry 1989;92(6):505-13.
1988: Pedro Fernández-Llebrez; Juan Pérez; A E Nadales; M Cifuentes; JM Grondona; J M Mancera; Esteban M Rodríguez
Immunocytochemical study of the hypothalamic magnocellular neurosecretory nuclei of the snake Natrix maura and the turtle Mauremys caspica.
Cell and tissue research 1988;253(2):435-45.
1988: H D Dellmann; Esteban M Rodríguez; P Peña; I Siegmund
Immunohistochemical investigation of the magnocellular peptidergic hypothalamo-neurohypophysial system of the rat chronically stimulated by long-term administration of hypertonic saline.
Neuroendocrinology 1988;47(4):335-42.
1988: P Peña; Esteban M Rodríguez; H D Dellmann; K Schoebitz
Effects of colchicine on the hypothalamo-neurohypophysial system of chronically salt-loaded rats.
Neuroendocrinology 1988;47(3):217-24.
1988: Esteban M Rodríguez; H W Korf; A Oksche; Carlos R Yulis; Silvia Hein
Pinealocytes immunoreactive with antisera against secretory glycoproteins of the subcommissural organ: a comparative study.
Cell and tissue research 1988;254(3):469-80.
1987: Pedro Fernández-Llebrez; Juan Pérez; M Cifuentes; G Alvial; Esteban M Rodríguez
Immunocytochemical and ultrastructural evidence for a neurophysinergic innervation of the subcommissural organ of the snake Natrix maura.
Cell and tissue research 1987;248(2):473-8.
1987: Pedro Fernández-Llebrez; Juan Pérez; A E Nadales; José-Manuel Pérez-Fígares; Esteban M Rodríguez
Vascular and leptomeningeal projections of the subcommissural organ in reptiles. Lectin-histochemical, immunocytochemical, and ultrastructural studies.
Histochemistry 1987;87(6):607-14.
1986: K Schoebitz; O Garrido; M Heinrichs; L Speer; Esteban M Rodríguez
Ontogenetical development of the chick and duck subcommissural organ. An immunocytochemical study.
Histochemistry 1986;84(1):31-40.
1986: Esteban M Rodríguez; H Herrera; B Peruzzo; Sara Rodríguez; Silvia Hein; A Oksche
Light- and electron-microscopic immunocytochemistry and lectin histochemistry of the subcommissural organ: evidence for processing of the secretory material.
Cell and tissue research 1986;243(3):545-59.
1984: Carlos R Yulis; B Peruzzo; Esteban M Rodríguez
Immunocytochemistry and ultrastructure of the neuropil located ventral to the rat supraoptic nucleus.
Cell and tissue research 1984;236(1):171-80.
1984: Esteban M Rodríguez; A Oksche; Silvia Hein; Sara Rodríguez; R Yulis
Spatial and structural interrelationships between secretory cells of the subcommissural organ and blood vessels. An immunocytochemical study.
Cell and tissue research 1984;237(3):443-9.
1984: Esteban M Rodríguez; A Oksche; Silvia Hein; Sara Rodríguez; R Yulis
Comparative immunocytochemical study of the subcommissural organ.
Cell and tissue research 1984;237(3):427-41.
1984: Esteban M Rodríguez; R Yulis; B Peruzzo; G Alvial; R Andrade
Standardization of various applications of methacrylate embedding and silver methenamine for light and electron microscopy immunocytochemistry.
Histochemistry 1984;81(3):253-63.
1982: Carlos R Yulis; Esteban M Rodríguez
Neurophysin pathways in the normal and hypophysectomized rat.
Cell and tissue research 1982;227(1):93-112.
1981: L I Aguado; K Schoebitz; Esteban M Rodríguez
Intercellular channels in the pars tuberalis of the rat hypophysis and their relationship to the subarachnoid space.
Cell and tissue research 1981;218(2):345-54.