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Bill Roebuck
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Living Beings
Chemicals & Drugs
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Network (preview)
31
Kensler, Thomas
22
Groopman, John
16
Curphey, Thomas
14
Longnecker, Daniel
12
Egner, Patricia
8
Sutter, Thomas
5
Bodreddigari, Sridevi
3
Sutter, Carrie Hayes
3
Yager, James
2
Yore, Mark
2
Dolan, Patrick
2
Sporn, Michael B.
2
Bailey, George
2
Honda, Tadashi
2
Gange, Stephen
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All Publications
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2009: Roebuck Bill D; Johnson Denise N; Sutter Carrie Hayes; Egner Patricia A; Scholl Peter F; Friesen Marlin D; Baumgartner Karen J; Ware Nicholas M; Bodreddigari Sridevi; Groopman John D; Kensler Thomas W; Sutter Thomas R
Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.
Toxicological sciences : an official journal of the Society of Toxicology 2009;109(1):41-9.
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2009: Tran Quynh T; Xu Lijing; Phan Vinhthuy; Goodwin Shirlean B; Rahman Mostafizur; Jin Victor X; Sutter Carrie H; Roebuck Bill D; Kensler Thomas W; George E Olusegun; Sutter Thomas R
Chemical genomics of cancer chemopreventive dithiolethiones.
Carcinogenesis 2009;30(3):480-6.
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2008: Liby Karen; Yore Mark M; Roebuck Bill D; Baumgartner Karen J; Honda Tadashi; Sundararajan Chitra; Yoshizawa Hidenori; Gribble Gordon W; Williams Charlotte R; Risingsong Renee; Royce Darlene B; Dinkova-Kostova Albena T; Stephenson Katherine K; Egner Patricia A; Yates Melinda S; Groopman John D; Kensler Thomas W; Sporn Michael B
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.
Cancer research 2008;68(16):6727-33.
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2008: Bodreddigari Sridevi; Jones Laundette Knight; Egner Patricia A; Groopman John D; Sutter Carrie Hayes; Roebuck Bill D; Guengerich F Peter; Kensler Thomas W; Sutter Thomas R
Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3.
Chemical research in toxicology 2008;21(5):1134-42.
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2008: Johnson Denise N; Egner Patricia A; Obrian Greg; Glassbrook Norman; Roebuck Bill D; Sutter Thomas R; Payne Gary A; Kensler Thomas W; Groopman John D
Quantification of urinary aflatoxin B1 dialdehyde metabolites formed by aflatoxin aldehyde reductase using isotope dilution tandem mass spectrometry.
Chemical research in toxicology 2008;21(3):752-60.
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2007: Simonich Michael T; Egner Patricia A; Roebuck Bill D; Orner Gayle A; Jubert Carole; Pereira Cliff; Groopman John D; Kensler Thomas W; Dashwood Roderick H; Williams David E; Bailey George S
Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.
Carcinogenesis 2007;28(6):1294-302.
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2007: Kitareewan Sutisak; Roebuck B D; Demidenko Eugene; Sloboda Roger D; Dmitrovsky Ethan
Lysosomes and trivalent arsenic treatment in acute promyelocytic leukemia.
Journal of the National Cancer Institute 2007;99(1):41-52.
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2006: Karuri Asok R; Huang Yong; Bodreddigari Sridevi; Sutter Carrie Hayes; Roebuck Bill D; Kensler Thomas W; Sutter Thomas R
3H-1,2-dithiole-3-thione targets nuclear factor kappaB to block expression of inducible nitric-oxide synthase, prevents hypotension, and improves survival in endotoxemic rats.
The Journal of pharmacology and experimental therapeutics 2006;317(1):61-7.
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2006: Yates Melinda S; Kwak Mi-Kyoung; Egner Patricia A; Groopman John D; Bodreddigari Sridevi; Sutter Thomas R; Baumgartner Karen J; Roebuck B D; Liby Karen T; Yore Mark M; Honda Tadashi; Gribble Gordon W; Sporn Michael B; Kensler Thomas W
Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
Cancer research 2006;66(4):2488-94.
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2006: Orner Gayle A; Roebuck Bill D; Dashwood Roderick H; Bailey George S
Post-initiation chlorophyllin exposure does not modulate aflatoxin-induced foci in the liver and colon of rats.
Journal of carcinogenesis 2006;5():6.
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2004: Roebuck B D
Hyperplasia, partial hepatectomy, and the carcinogenicity of aflatoxin B1.
Journal of cellular biochemistry 2004;91(2):243-9.
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2003: Roebuck B D; Curphey Thomas J; Li Yuan; Baumgartner Karen J; Bodreddigari Sridevi; Yan Jian; Gange Stephen J; Kensler Thomas W; Sutter Thomas R
Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz.
Carcinogenesis 2003;24(12):1919-28.
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2003: Egner Patricia A; Yu Xiang; Johnson Jesse K; Nathasingh Christopher K; Groopman John D; Kensler Thomas W; Roebuck Bill D
Identification of aflatoxin M1-N7-guanine in liver and urine of tree shrews and rats following administration of aflatoxin B1.
Chemical research in toxicology 2003;16(9):1174-80.
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2000: Li Y; Su J; Qin L; Egner P A; Wang J; Groopman J D; Kensler T W; Roebuck B D
Reduction of aflatoxin B(1) adduct biomarkers by oltipraz in the tree shrew (Tupaia belangeri chinensis).
Cancer letters 2000;154(1):79-83.
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2000: Kensler T W; Curphey T J; Maxiutenko Y; Roebuck B D
Chemoprotection by organosulfur inducers of phase 2 enzymes: dithiolethiones and dithiins.
Drug metabolism and drug interactions 2000;17(1-4):3-22.
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1999: Kensler T W; Groopman J D; Sutter T R; Curphey T J; Roebuck B D
Development of cancer chemopreventive agents: oltipraz as a paradigm.
Chemical research in toxicology 1999;12(2):113-26.
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1998: Maxuitenko Y Y; Libby A H; Joyner H H; Curphey T J; MacMillan D L; Kensler T W; Roebuck B D
Identification of dithiolethiones with better chemopreventive properties than oltipraz.
Carcinogenesis 1998;19(9):1609-15.
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1998: Kensler T W; Groopman J D; Roebuck B D
Use of aflatoxin adducts as intermediate endpoints to assess the efficacy of chemopreventive interventions in animals and man.
Mutation research 1998;402(1-2):165-72.
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1997: Kensler T W; Gange S J; Egner P A; Dolan P M; Muñoz A; Groopman J D; Rogers A E; Roebuck B D
Predictive value of molecular dosimetry: individual versus group effects of oltipraz on aflatoxin-albumin adducts and risk of liver cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(8):603-10.
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1997: Roebuck B D; Rogers A E; Kensler T W
Correspondence re: C.V. Rao, et al., Inhibition of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced lymphoma formation by oltipraz. Cancer Res., 56: 3395-3398, 1996.
Cancer research 1997;57(13):2806-7.
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1997: Maxuitenko Y Y; North W G; Roebuck B D
Urinary taurine as a non-invasive marker of aflatoxin B1-induced hepatotoxicity: success and failure.
Toxicology 1997;118(2-3):159-69.
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1996: Maxuitenko Y Y; Curphey T J; Kensler T W; Roebuck B D
Protection against aflatoxin B1-induced hepatic toxicity as short-term screen of cancer chemopreventive dithiolethiones.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;32(2):250-9.
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1995: Primiano T; Egner P A; Sutter T R; Kelloff G J; Roebuck B D; Kensler T W
Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases.
Cancer research 1995;55(19):4319-24.
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1994: Craven-Giles T; Tagliaferro A R; Ronan A M; Baumgartner K J; Roebuck B D
Dietary modulation of pancreatic carcinogenesis: calories and energy expenditure.
Cancer research 1994;54(7 Suppl):1964s-1968s.
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1994: Groopman J D; Wogan G N; Roebuck B D; Kensler T W
Molecular biomarkers for aflatoxins and their application to human cancer prevention.
Cancer research 1994;54(7 Suppl):1907s-1911s.
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1994: Groopman J D; Roebuck B D; Kensler T W
Carcinogen-DNA and protein adducts as intermediate biomarkers for human chemoprotection trials.
Advances in experimental medicine and biology 1994;354():149-60.
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1993: Maxuitenko Y Y; MacMillan D L; Kensler T W; Roebuck B D
Evaluation of the post-initiation effects of oltipraz on aflatoxin B1-induced preneoplastic foci in a rat model of hepatic tumorigenesis.
Carcinogenesis 1993;14(11):2423-5.
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1993: Bolton M G; Muñoz A; Jacobson L P; Groopman J D; Maxuitenko Y Y; Roebuck B D; Kensler T W
Transient intervention with oltipraz protects against aflatoxin-induced hepatic tumorigenesis.
Cancer research 1993;53(15):3499-504.
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1993: Roebuck B D; Baumgartner K J; MacMillan D L
Caloric restriction and intervention in pancreatic carcinogenesis in the rat.
Cancer research 1993;53(1):46-52.
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1993: Kensler T W; Davidson N E; Groopman J D; Roebuck B D; Prochaska H J; Talalay P
Chemoprotection by inducers of electrophile detoxication enzymes.
Basic life sciences 1993;61():127-36.
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1992: Kensler T W; Groopman J D; Eaton D L; Curphey T J; Roebuck B D
Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
Carcinogenesis 1992;13(1):95-100.
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1992: Giles T C; Roebuck B D
Effects of voluntary exercise and/or food restriction on pancreatic tumorigenesis in male rats.
Advances in experimental medicine and biology 1992;322():17-27.
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1992: Tagliaferro A R; Roebuck B D; Ronan A M; Meeker L D
Enhancement of pancreatic carcinogenesis by dehydroepiandrosterone.
Advances in experimental medicine and biology 1992;322():119-29.
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1992: Groopman J D; Roebuck B D; Kensler T W
Molecular dosimetry of aflatoxin DNA adducts in humans and experimental rat models.
Progress in clinical and biological research 1992;374():139-55.
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1992: Kensler T; Styczynski P; Groopman J; Helzlsouer K; Curphey T; Maxuitenko Y; Roebuck B D
Mechanisms of chemoprotection by oltipraz.
Journal of cellular biochemistry. Supplement 1992;16I():167-72.
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1991: Roebuck B D; Liu Y L; Rogers A E; Groopman J D; Kensler T W
Protection against aflatoxin B1-induced hepatocarcinogenesis in F344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry.
Cancer research 1991;51(20):5501-6.
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1990: Roebuck B D; McCaffrey J; Baumgartner K J
Protective effects of voluntary exercise during the postinitiation phase of pancreatic carcinogenesis in the rat.
Cancer research 1990;50(21):6811-6.
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1990: Longnecker D S; Roebuck B D; Curphey T J; MacMillan D L
Evaluation of promotion of pancreatic carcinogenesis in rats by benzyl acetate.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1990;28(10):665-8.
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1989: Sumi C; Longnecker D S; Roebuck B D; Brinck-Johnsen T
Inhibitory effects of estrogen and castration on the early stage of pancreatic carcinogenesis in Fischer rats treated with azaserine.
Cancer research 1989;49(9):2332-6.
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1988: Lhoste E F; Roebuck B D; Longnecker D S
Stimulation of the growth of azaserine-induced nodules in the rat pancreas by dietary camostate (FOY-305).
Carcinogenesis 1988;9(6):901-6.
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1988: Liu Y L; Roebuck B D; Yager J D; Groopman J D; Kensler T W
Protection by 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) against the hepatotoxicity of aflatoxin B1 in the rat.
Toxicology and applied pharmacology 1988;93(3):442-51.
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1988: Curphey T J; Kuhlmann E T; Roebuck B D; Longnecker D S
Inhibition of pancreatic and liver carcinogenesis in rats by retinoid- and selenium-supplemented diets.
Pancreas 1988;3(1):36-40.
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1987: Roebuck B D; Baumgartner K J; Longnecker D S
Growth of pancreatic foci and development of pancreatic cancer with a single dose of azaserine in the rat.
Carcinogenesis 1987;8(12):1831-5.
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1987: Longnecker D S; Kuhlmann E T; Roebuck B D; Curphey T J
Pancreatic carcinogenesis in azaserine-treated rats: inhibition by a solvent mixture in the diet.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1987;25(11):823-8.
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1987: Kensler T W; Egner P A; Dolan P M; Groopman J D; Roebuck B D
Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.
Cancer research 1987;47(16):4271-7.
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1987: Lhoste E F; Roebuck B D; Brinck-Johnsen T; Longnecker D S
Effect of castration and hormone replacement on azaserine-induced pancreatic carcinogenesis in male and female Fischer rats.
Carcinogenesis 1987;8(5):699-703.
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1987: Lhoste E F; Roebuck B D; Stern J E; Longnecker D S
Effect of orchiectomy and testosterone on the early stages of azaserine-induced pancreatic carcinogenesis in the rat.
Pancreas 1987;2(1):38-43.
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1986: Longnecker D S; Roebuck B D; Curphey T J; Lhoste E; Coon C I; MacMillan D
Effects of corn oil and benzyl acetate on number and size of azaserine-induced foci in the pancreas of LEW and F344 rats.
Environmental health perspectives 1986;68():197-201.
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1986: Kensler T W; Egner P A; Davidson N E; Roebuck B D; Pikul A; Groopman J D
Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.
Cancer research 1986;46(8):3924-31.
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1986: Longnecker D S; Curphey T J; Kuhlmann E T; Roebuck B D; Neff R K
Effects of retinoids in N-nitrosobis(2-oxopropyl)amine-treated hamsters.
Pancreas 1986;1(3):224-31.
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1985: Roebuck B D; Longnecker D S; Baumgartner K J; Thron C D
Carcinogen-induced lesions in the rat pancreas: effects of varying levels of essential fatty acid.
Cancer research 1985;45(11 Pt 1):5252-6.
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1985: Longnecker D S; Roebuck B D; Kuhlmann E T; Curphey T J
Induction of pancreatic carcinomas in rats with N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine: histopathology.
Journal of the National Cancer Institute 1985;74(1):209-17.
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1984: Roebuck B D; Baumgartner K J; Thron C D; Longnecker D S
Inhibition by retinoids of the growth of azaserine-induced foci in the rat pancreas.
Journal of the National Cancer Institute 1984;73(1):233-6.
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1984: Zurlo J; Roebuck B D; Rutkowski J V; Curphey T J; Longnecker D S
Effect of pyridoxal deficiency on pancreatic DNA damage and nodule induction by azaserine.
Carcinogenesis 1984;5(5):555-8.
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1984: Roebuck B D; Baumgartner K J; Thron C D
Characterization of two populations of pancreatic atypical acinar cell foci induced by azaserine in the rat.
Laboratory investigation; a journal of technical methods and pathology 1984;50(2):141-6.
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1982: Longnecker D S; Curphey T J; Kuhlmann E T; Roebuck B D
Inhibition of pancreatic carcinogenesis by retinoids in azaserine-treated rats.
Cancer research 1982;42(1):19-24.
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1981: Yager J D; Roebuck B D; Zurlo J; Longnecker D S; Weselcouch E O; Wilpone S A
A single-dose protocol for azaserine initiation of pancreatic carcinogenesis in the rat.
International journal of cancer. Journal international du cancer 1981;28(5):601-6.
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1981: Roebuck B D; Yager J D; Longnecker D S; Wilpone S A
Promotion by unsaturated fat of azaserine-induced pancreatic carcinogenesis in the rat.
Cancer research 1981;41(10):3961-6.
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1980: Roebuck B D; Lilja H S; Curphey T J; Longnecker D S
Pathologic and biochemical effects of azaserine in inbred Wistar/Lewis rats and noninbred CD-1 mice.
Journal of the National Cancer Institute 1980;65(2):383-9.
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