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Karen Roelofs

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Adriana Laser; Christine L Lau; Guanyi Lu; Brendan McEvoy; Karen J Roelofs; Gang Su; Gorav Ailawadi; Castigliano M Bhamidipati; Paul DiMusto; Jonathan L Eliason; Abhijit Ghosh; Peter K Henke; Yunge Zhao; Gilbert R Upchurch Jr
Differential gender- and species-specific formation of aneurysms using a novel method of inducing abdominal aortic aneurysms.
Paul D DiMusto; Jonathan L Eliason; Abhijit Ghosh; Peter K Henke; Adriana Laser; Guanyi Lu; Brendan McEvoy; Karen J Roelofs; Omar Sadiq; Gang Su; Gorav Ailawadi; Castigliano M Bhamidipati; Gilbert R Upchurch Jr
Increased JNK in males compared with females in a rodent model of abdominal aortic aneurysm.
Paul D DiMusto; Jonathan L Eliason; Abhijit Ghosh; Peter K Henke; Adriana Laser; Christine L Lau; Guanyi Lu; Brendan McEvoy; Karen J Roelofs; Omar Sadiq; Gang Su; Thomas W Wakefield; Yunge Zhao; Jose Antonio Diaz; Gilbert R Upchurch Jr
Increased PAI-1 in females compared with males is protective for abdominal aortic aneurysm formation in a rodent model.

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All Publications

2012: Adriana Laser; Christine L Lau; Guanyi Lu; Brendan McEvoy; Karen J Roelofs; Gang Su; Gorav Ailawadi; Castigliano M Bhamidipati; Paul DiMusto; Jonathan L Eliason; Abhijit Ghosh; Peter K Henke; Yunge Zhao; Gilbert R Upchurch Jr
Differential gender- and species-specific formation of aneurysms using a novel method of inducing abdominal aortic aneurysms.
The Journal of surgical research 2012;178(2):1038-45.
2012: Paul D DiMusto; Jonathan L Eliason; Abhijit Ghosh; Peter K Henke; Adriana Laser; Guanyi Lu; Brendan McEvoy; Karen J Roelofs; Omar Sadiq; Gang Su; Gorav Ailawadi; Castigliano M Bhamidipati; Gilbert R Upchurch Jr
Increased JNK in males compared with females in a rodent model of abdominal aortic aneurysm.
The Journal of surgical research 2012;176(2):687-95.
2012: Paul D DiMusto; Jonathan L Eliason; Abhijit Ghosh; Peter K Henke; Adriana Laser; Christine L Lau; Guanyi Lu; Brendan McEvoy; Karen J Roelofs; Omar Sadiq; Gang Su; Thomas W Wakefield; Yunge Zhao; Jose Antonio Diaz; Gilbert R Upchurch Jr
Increased PAI-1 in females compared with males is protective for abdominal aortic aneurysm formation in a rodent model.
American journal of physiology. Heart and circulatory physiology 2012;302(7):H1378-86.
2010: Lauren K Ehrlichman; John W Ford; Karen J Roelofs; Wagner Tedeschi-Filho; John S Futchko; Eduardo Ramacciotti; Jonathan L Eliason; Peter K Henke; Gilbert R Upchurch Jr
Gender-dependent differential phosphorylation in the ERK signaling pathway is associated with increased MMP2 activity in rat aortic smooth muscle cells.
The Journal of surgical research 2010;160(1):18-24.
2010: Brenda S Cho; Karen J Roelofs; John W Ford; Peter K Henke; Gilbert R Upchurch Jr
Decreased collagen and increased matrix metalloproteinase-13 in experimental abdominal aortic aneurysms in males compared with females.
Surgery 2010;147(2):258-67.
2009: Brenda S Cho; Derek T Woodrum; Karen J Roelofs; James C Stanley; Peter K Henke; Gilbert R Upchurch Jr
Differential regulation of aortic growth in male and female rodents is associated with AAA development.
The Journal of surgical research 2009;155(2):330-8.
2007: Indranil Sinha; Charles G Pearce; Brenda S Cho; Kevin K Hannawa; Karen J Roelofs; James C Stanley; Peter K Henke; Gilbert R Upchurch Jr
Differential regulation of the superoxide dismutase family in experimental aortic aneurysms and rat aortic explants.
The Journal of surgical research 2007;138(2):156-62.
2006: Indranil Sinha; Brenda S Cho; Karen J Roelofs; James C Stanley; Peter K Henke; Gilbert R Upchurch Jr
Female gender attenuates cytokine and chemokine expression and leukocyte recruitment in experimental rodent abdominal aortic aneurysms.
Annals of the New York Academy of Sciences 2006;1085():367-79.
2006: Kevin K Hannawa; Brenda S Cho; Indranil Sinha; Karen J Roelofs; Daniel Durant Myers Jr; Thomas W Wakefield; James C Stanley; Peter K Henke; Gilbert R Upchurch Jr
Attenuation of experimental aortic aneurysm formation in P-selectin knockout mice.
Annals of the New York Academy of Sciences 2006;1085():353-9.
2006: Brenda S Cho; Karen J Roelofs; Istvan J Majoros; James R Baker Jr; James C Stanley; Peter K Henke; Gilbert R Upchurch Jr
Diffusion of Alexa Fluor 488-conjugated dendrimers in rat aortic tissue.
Annals of the New York Academy of Sciences 2006;1085():294-305.
2006: Matthew J Eagleton; Brenda Cho; Erin Lynch; Karen J Roelofs; Derek T Woodrum; James C Stanley; Gilbert R Upchurch Jr
Alterations in angiotensin converting enzyme during rodent aortic aneurysm formation.
The Journal of surgical research 2006;132(1):69-73.
2006: Indranil Sinha; Siddharth Bethi; Paul Cronin; david m williams; Karen J Roelofs; Gorav Ailawadi; Peter K Henke; Matthew J Eagleton; G Michael Deeb; Himanshu J Patel; Ramon Berguer; James C Stanley; Gilbert R Upchurch Jr
A biologic basis for asymmetric growth in descending thoracic aortic aneurysms: a role for matrix metalloproteinase 9 and 2.
Journal of vascular surgery 2006;43(2):342-8.
2005: Jonathan L Eliason; Kevin K Hannawa; Gorav Ailawadi; Indranil Sinha; John W Ford; Michael P Deogracias; Karen J Roelofs; Derek T Woodrum; Terri Ennis; Peter K Henke; James C Stanley; Robert W Thompson; Gilbert R Upchurch Jr
Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation.
Circulation 2005;112(2):232-40.
2005: Kevin K Hannawa; Jonathan L Eliason; Derek T Woodrum; Charles G Pearce; Karen J Roelofs; Vladimir Grigoryants; Matthew J Eagleton; Peter K Henke; Thomas W Wakefield; Daniel Durant Myers Jr; James C Stanley; Gilbert R Upchurch Jr
L-selectin-mediated neutrophil recruitment in experimental rodent aneurysm formation.
Circulation 2005;112(2):241-7.
2005: Vladimir Grigoryants; Kevin K Hannawa; Charles G Pearce; Indranil Sinha; Karen J Roelofs; Gorav Ailawadi; K Barry Deatrick; Derek T Woodrum; Brenda S Cho; Peter K Henke; James C Stanley; Matthew J Eagleton; Gilbert R Upchurch Jr
Tamoxifen up-regulates catalase production, inhibits vessel wall neutrophil infiltration, and attenuates development of experimental abdominal aortic aneurysms.
Journal of vascular surgery 2005;41(1):108-14.
2004: Gorav Ailawadi; Jonathan L Eliason; Karen J Roelofs; Indranil Sinha; Kevin K Hannawa; Eric P Kaldjian; Guanyi Lu; Peter K Henke; James C Stanley; Stephen J Weiss; Robert W Thompson; Gilbert R Upchurch Jr
Gender differences in experimental aortic aneurysm formation.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(11):2116-22.
2004: Indranil Sinha; Kevin K Hannawa; Jonathan L Eliason; Gorav Ailawadi; Michael P Deogracias; Siddharth Bethi; John W Ford; Karen J Roelofs; Vladimir Grigoryants; Peter K Henke; James C Stanley; Gilbert R Upchurch Jr
Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms.
Surgery 2004;136(2):176-82.
2004: Brian S Knipp; Gorav Ailawadi; John W Ford; David A Peterson; Matthew J Eagleton; Karen J Roelofs; Kevin K Hannawa; Michael P Deogracias; Baoan Ji; Craig D Logsdon; Kathleen Graziano; Diane M Simeone; Robert W Thompson; Peter K Henke; James C Stanley; Gilbert R Upchurch Jr
Increased MMP-9 expression and activity by aortic smooth muscle cells after nitric oxide synthase inhibition is associated with increased nuclear factor-kappaB and activator protein-1 activity.
The Journal of surgical research 2004;116(1):70-80.
2003: Brian S Knipp; Gorav Ailawadi; Vita V Sullivan; Karen J Roelofs; Peter K Henke; James C Stanley; Gilbert R Upchurch Jr
Ultrasound measurement of aortic diameters in rodent models of aneurysm disease.
The Journal of surgical research 2003;112(1):97-101.
2003: Gorav Ailawadi; Brian S Knipp; Guanyi Lu; Karen J Roelofs; John W Ford; Kevin K Hannawa; D Keith Bishop; Porama Thanaporn; Peter K Henke; James C Stanley; Gilbert R Upchurch Jr
A nonintrinsic regional basis for increased infrarenal aortic MMP-9 expression and activity.
Journal of vascular surgery 2003;37(5):1059-66.
2002: Matthew J Eagleton; David A Peterson; Vita V Sullivan; Karen J Roelofs; John A Ford; James C Stanley; Gilbert R Upchurch Jr
Nitric oxide inhibition increases aortic wall matrix metalloproteinase-9 expression.
The Journal of surgical research 2002;104(1):15-21.