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Jürgen Roes

Research Profile

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TOP 3
Adam Lacy-Hulbert; Aileen M Smith; Hamid Tissire; Marc Barry; Denise Crowley; Roderick T Bronson; Jürgen Roes; John Savill; Richard O Hynes
Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins.
Jürgen Roes
Conditional mutagenesis reveals immunological functions of widely expressed genes: activation thresholds, homeostatic mechanisms and disease models.
Felix Chua; Sarah E Dunsmore; Peter H Clingen; Steven E Mutsaers; Steven D Shapiro; Anthony W Segal; Jürgen Roes; Geoffrey J Laurent
Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis.

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All Publications

2007: Adam Lacy-Hulbert; Aileen M Smith; Hamid Tissire; Marc Barry; Denise Crowley; Roderick T Bronson; Jürgen Roes; John Savill; Richard O Hynes
Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(40):15823-8.
2007: Jürgen Roes
Conditional mutagenesis reveals immunological functions of widely expressed genes: activation thresholds, homeostatic mechanisms and disease models.
Handbook of experimental pharmacology 2007;(178):289-314.
2007: Felix Chua; Sarah E Dunsmore; Peter H Clingen; Steven E Mutsaers; Steven D Shapiro; Anthony W Segal; Jürgen Roes; Geoffrey J Laurent
Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis.
The American journal of pathology 2007;170(1):65-74.
2006: Maurizio D'Antonio; Anna Droggiti; M Laura Feltri; Jürgen Roes; Lawrence Wrabetz; Rhona Mirsky; Kristjan R Jessen
TGFbeta type II receptor signaling controls Schwann cell death and proliferation in developing nerves.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(33):8417-27.
2006: Ping Xu; Jürgen Roes; Anthony W Segal; Marko Radulovic
The role of grancalcin in adhesion of neutrophils.
Cellular immunology 2006;240(2):116-21.
2005: N Avrion Mitchison; Marcus Harbord; A Hankin; Jürgen Roes
Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.
Immunology letters 2005;97(1):63-7.
2005: Joseph H McCarty; Adam Lacy-Hulbert; Al Charest; Roderick T Bronson; Denise Crowley; David E Housman; John Savill; Jürgen Roes; Richard O Hynes
Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death.
Development (Cambridge, England) 2005;132(1):165-76.
2004: Stefan Borsutzky; Balthazar B Cazac; Jürgen Roes; Carlos A Guzmán
TGF-beta receptor signaling is critical for mucosal IgA responses.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3305-9.
2004: Richard M Thomas; Christian Schmedt; Marco Novelli; B Ken Choi; Jane A Skok; Alexander Tarakhovsky; Jürgen Roes
C-terminal SRC kinase controls acute inflammation and granulocyte adhesion.
Immunity 2004;20(2):181-91.
2003: Jürgen Roes; B Ken Choi; Balthazar B Cazac
Redirection of B cell responsiveness by transforming growth factor beta receptor.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(12):7241-6.
2003: York Rudhard; Matthias Kneussel; Mohammed A Nassar; Georg F Rast; Alexander Annala; Philip E Chen; Cezar M Tigaret; Isabel Dean; Jürgen Roes; Alasdair J Gibb; Stephen P Hunt; Ralf Schoepfer
Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(6):2323-32.
2003: Jürgen Roes; B Ken Choi; David Power; Ping Xu; Anthony W Segal
Granulocyte function in grancalcin-deficient mice.
Molecular and cellular biology 2003;23(3):826-30.
2002: N Avrion Mitchison; Jürgen Roes
Patterned variation in murine MHC promoters.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10561-6.
2002: Carlo G M Messina; Emer P Reeves; Jürgen Roes; Anthony W Segal
Catalase negative Staphylococcus aureus retain virulence in mouse model of chronic granulomatous disease.
FEBS letters 2002;518(1-3):107-10.
2002: Emer P Reeves; Hui Lu; Hugues Lortat Jacobs; Carlo G M Messina; Steve Bolsover; Giorgio Gabella; Eric O Potma; Alice Warley; Jürgen Roes; Anthony W Segal
Killing activity of neutrophils is mediated through activation of proteases by K+ flux.
Nature 2002;416(6878):291-7.
2002: Marcus Harbord; Marco Novelli; Benito Canas; David Power; Christine Davis; Jasminka Godovac-Zimmermann; Jürgen Roes; Anthony W Segal
Ym1 is a neutrophil granule protein that crystallizes in p47phox-deficient mice.
The Journal of biological chemistry 2002;277(7):5468-75.
2001: Sarah E Dunsmore; Jürgen Roes; Felix Chua; Anthony W Segal; Steven E Mutsaers; Geoffrey J Laurent
Evidence that neutrophil elastase-deficient mice are resistant to bleomycin-induced fibrosis.
Chest 2001;120(1 Suppl):35S-36S.
2001: Adam Lacy-Hulbert; R Thomas; X P Li; Caroline E Lilley; Robert S Coffin; Jürgen Roes
Interruption of coding sequences by heterologous introns can enhance the functional expression of recombinant genes.
Gene therapy 2001;8(8):649-53.
2000: Balthazar B Cazac; Jürgen Roes
TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo.
Immunity 2000;13(4):443-51.
2000: Lodewijk Dekker; M Leitges; G Altschuler; N Mistry; A McDermott; Jürgen Roes; Anthony W Segal
Protein kinase C-beta contributes to NADPH oxidase activation in neutrophils.
The Biochemical journal 2000;347 Pt 1():285-9.
2000: J Tkalcevic; Marco Novelli; M Phylactides; J P Iredale; Anthony W Segal; Jürgen Roes
Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G.
Immunity 2000;12(2):201-10.
1999: Tim E Hawkins; Jürgen Roes; D Rees; Jayne Monkhouse; Stephen E Moss
Immunological development and cardiovascular function are normal in annexin VI null mutant mice.
Molecular and cellular biology 1999;19(12):8028-32.