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Roger Roeske

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Chemicals & Drugs

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TOP 3
Sipho Mamputha; Zhi-Liang Lu; Roger W Roeske; Robert P Millar; Arieh A Katz; Colleen A Flanagan
Conserved amino acid residues that are important for ligand binding in the type I gonadotropin-releasing hormone (GnRH) receptor are required for high potency of GnRH II at the type II GnRH receptor.
Perdita E Barran; Roger W Roeske; Adam J Pawson; Robin Sellar; Michael T Bowers; Kevin Morgan; Zhi-Liang Lu; Motoyuki Tsuda; Takehiro Kusakabe; Robert P Millar
Evolution of constrained gonadotropin-releasing hormone ligand conformation and receptor selectivity.
Thomas R Ott; Brigitte E Troskie; Roger W Roeske; Nicola Illing; Colleen A Flanagan; Robert P Millar
Two mutations in extracellular loop 2 of the human GnRH receptor convert an antagonist to an agonist.

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All Publications

2007: Sipho Mamputha; Zhi-Liang Lu; Roger W Roeske; Robert P Millar; Arieh A Katz; Colleen A Flanagan
Conserved amino acid residues that are important for ligand binding in the type I gonadotropin-releasing hormone (GnRH) receptor are required for high potency of GnRH II at the type II GnRH receptor.
Molecular endocrinology (Baltimore, Md.) 2007;21(1):281-92.
2005: Perdita E Barran; Roger W Roeske; Adam J Pawson; Robin Sellar; Michael T Bowers; Kevin Morgan; Zhi-Liang Lu; Motoyuki Tsuda; Takehiro Kusakabe; Robert P Millar
Evolution of constrained gonadotropin-releasing hormone ligand conformation and receptor selectivity.
The Journal of biological chemistry 2005;280(46):38569-75.
2002: Thomas R Ott; Brigitte E Troskie; Roger W Roeske; Nicola Illing; Colleen A Flanagan; Robert P Millar
Two mutations in extracellular loop 2 of the human GnRH receptor convert an antagonist to an agonist.
Molecular endocrinology (Baltimore, Md.) 2002;16(5):1079-88.
2001: Bernhard J Fromme; Arieh A Katz; Roger W Roeske; Robert P Millar; Colleen A Flanagan
Role of aspartate7.32(302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation.
Molecular pharmacology 2001;60(6):1280-7.
1999: D Assefa; Adam J Pawson; Craig A McArdle; Robert P Millar; Colleen A Flanagan; Roger W Roeske; James S Davidson
A new photoreactive antagonist cross-links to the N-terminal domain of the gonadotropin-releasing hormone receptor.
Molecular and cellular endocrinology 1999;156(1-2):179-88.
1997: James S Davidson; D Assefa; Adam J Pawson; P Davies; JP Hapgood; I Becker; Colleen A Flanagan; Roger W Roeske; Robert Millar
Irreversible activation of the gonadotropin-releasing hormone receptor by photoaffinity cross-linking: localization of attachment site to Cys residue in N-terminal segment.
Biochemistry 1997;36(42):12881-9.
1995: G F Jacobs; Colleen A Flanagan; Roger W Roeske; Robert P Millar
Agonist activity of mammalian gonadotropin-releasing antagonists in chicken gonadotropes reflects marked differences in vertebrate gonadotropin-releasing receptors.
Molecular and cellular endocrinology 1995;108(1-2):107-13.
1993: James S Davidson; A Eales; Roger W Roeske; Robert P Millar
Inhibition of pituitary hormone exocytosis by a synthetic peptide related to the rab effector domain.
FEBS letters 1993;326(1-3):219-21.