Vera Rogiers

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De Kock Joery; Vanhaecke Tamara; Biernaskie Jeffrey; Rogiers Vera; Snykers Sarah
Characterization and hepatic differentiation of skin-derived precursors from adult foreskin by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development.
De Vuyst Elke; Wang Nan; Decrock Elke; De Bock Marijke; Vinken Mathieu; Van Moorhem Marijke; Lai Charles; Culot Maxime; Rogiers Vera; Cecchelli Romeo; Naus Christian C; Evans W Howard; Leybaert Luc
Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells.
De Vocht Caroline; Ranquin An; Willaert Ronnie; Van Ginderachter Jo A; Vanhaecke Tamara; Rogiers Vera; Versées Wim; Van Gelder Patrick; Steyaert Jan
Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE.

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All Publications

2009: De Kock Joery; Vanhaecke Tamara; Biernaskie Jeffrey; Rogiers Vera; Snykers Sarah
Characterization and hepatic differentiation of skin-derived precursors from adult foreskin by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(8):1522-7.
2009: De Vuyst Elke; Wang Nan; Decrock Elke; De Bock Marijke; Vinken Mathieu; Van Moorhem Marijke; Lai Charles; Culot Maxime; Rogiers Vera; Cecchelli Romeo; Naus Christian C; Evans W Howard; Leybaert Luc
Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells.
Cell calcium 2009;46(3):176-87.
2009: De Vocht Caroline; Ranquin An; Willaert Ronnie; Van Ginderachter Jo A; Vanhaecke Tamara; Rogiers Vera; Versées Wim; Van Gelder Patrick; Steyaert Jan
Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE.
Journal of controlled release : official journal of the Controlled Release Society 2009;137(3):246-54.
2009: Fraczek Joanna; Deleu Sarah; Lukaszuk Aneta; Doktorova Tatyana; Tourwé Dirk; Geerts Albert; Vanhaecke Tamara; Vanderkerken Karin; Rogiers Vera
Screening of amide analogues of Trichostatin A in cultures of primary rat hepatocytes: search for potent and safe HDAC inhibitors.
Investigational new drugs 2009;27(4):338-46.
2009: Vinken Mathieu; Doktorova Tatyana; Decrock Elke; Leybaert Luc; Vanhaecke Tamara; Rogiers Vera
Gap junctional intercellular communication as a target for liver toxicity and carcinogenicity.
Critical reviews in biochemistry and molecular biology 2009;44(4):201-22.
2009: Snykers Sarah; Henkens Tom; De Rop Evelien; Vinken Mathieu; Fraczek Joanna; De Kock Joery; De Prins Evi; Geerts Albert; Rogiers Vera; Vanhaecke Tamara
Role of epigenetics in liver-specific gene transcription, hepatocyte differentiation and stem cell reprogrammation.
Journal of hepatology 2009;51(1):187-211.
2009: Vinken Mathieu; Decrock Elke; De Vuyst Elke; Leybaert Luc; Vanhaecke Tamara; Rogiers Vera
Biochemical characterisation of an in vitro model of hepatocellular apoptotic cell death.
Alternatives to laboratory animals : ATLA 2009;37(2):209-18.
2009: Snykers Sarah; De Kock Joery; Rogiers Vera; Vanhaecke Tamara
In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art.
Stem cells (Dayton, Ohio) 2009;27(3):577-605.
2009: Vinken Mathieu; De Rop Evelien; Decrock Elke; De Vuyst Elke; Leybaert Luc; Vanhaecke Tamara; Rogiers Vera
Epigenetic regulation of gap junctional intercellular communication: more than a way to keep cells quiet?
Biochimica et biophysica acta 2009;1795(1):53-61.
2009: De Paepe K; Wibaux A; Ward C; Rogiers V
Skin efficacy and biophysical assessment of glycerol-containing hydrocolloid patches.
Skin pharmacology and physiology 2009;22(5):258-65.
2009: De Paepe K; Houben E; Adam R; Hachem J-P; Roseeuw D; Rogiers V
Seasonal effects on the nasolabial skin condition.
Skin pharmacology and physiology 2009;22(1):8-14.
2008: Houben Evi; Adam Ralf; Hachem Jean-Pierre; Roseeuw Diane; Rogiers Vera; De Paepe Kristien
Clinical scoring and biophysical evaluation of nasolabial skin barrier damage caused by rhinorrhea.
Contact dermatitis 2008;59(5):296-300.
2008: De Paepe Kristien; De Rop Evelien; Houben Evi; Adam Ralf; Rogiers Vera
Effects of lotioned disposable handkerchiefs on skin barrier recovery after tape stripping.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2008;14(4):440-7.
2008: Vinken Mathieu; Doktorova Tatyana; Ellinger-Ziegelbauer Heidrun; Ahr Hans-Jürgen; Lock Edward; Carmichael Paul; Roggen Erwin; van Delft Joost; Kleinjans Jos; Castell José; Bort Roque; Donato Teresa; Ryan Michael; Corvi Raffaella; Keun Hector; Ebbels Timothy; Athersuch Toby; Sansone Susanna-Assunta; Rocca-Serra Philippe; Stierum Rob; Jennings Paul; Pfaller Walter; Gmuender Hans; Vanhaecke Tamara; Rogiers Vera
The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays.
Mutation research 2008;659(3):202-10.
2008: Henkens Tom; Vinken Mathieu; Lukaszuk Aneta; Tourwé Dirk; Vanhaecke Tamara; Rogiers Vera
Differential effects of hydroxamate histone deacetylase inhibitors on cellular functionality and gap junctions in primary cultures of mitogen-stimulated hepatocytes.
Toxicology letters 2008;178(1):37-43.
2008: Vinken Mathieu; Henkens Tom; De Rop Evelien; Fraczek Joanna; Vanhaecke Tamara; Rogiers Vera
Biology and pathobiology of gap junctional channels in hepatocytes.
Hepatology (Baltimore, Md.) 2008;47(3):1077-88.
2008: Rogiers Vera; Pauwels Marleen
Headlines of safety assessment of cosmetics in Europe and future perspectives.
Current problems in dermatology 2008;36():166-82.
2008: Rogiers Vera; Pauwels Marleen
The use of alternative methods in the safety assessment of cosmetic ingredients.
Current problems in dermatology 2008;36():129-65.
2008: Rogiers Vera; Pauwels Marleen
The cosmetic technical information file in practice.
Current problems in dermatology 2008;36():115-28.
2008: Rogiers Vera; Pauwels Marleen
Safety assessment of cosmetic ingredients present in technical information files of finished products.
Current problems in dermatology 2008;36():94-114.
2008: Rogiers Vera; Pauwels Marleen
Critical analysis of the safety assessment of cosmetic ingredients performed at the European level.
Current problems in dermatology 2008;36():58-93.
2008: Rogiers Vera; Pauwels Marleen
Challenges related to cosmetic safety assessment in the EU.
Current problems in dermatology 2008;36():29-57.
2008: Rogiers Vera; Pauwels Marleen
Cosmetic products and their current European regulatory framework.
Current problems in dermatology 2008;36():1-28.
2008: Houben E; Hachem J P; De Paepe K; Rogiers V
Epidermal ceramidase activity regulates epidermal desquamation via stratum corneum acidification.
Skin pharmacology and physiology 2008;21(2):111-8.
2007: Pauwels Marleen; Rogiers Vera
EU legislations affecting safety data availability of cosmetic ingredients.
Regulatory toxicology and pharmacology : RTP 2007;49(3):308-15.
2007: Pauwels Marleen; Rogiers Vera
Database search for safety information on cosmetic ingredients.
Regulatory toxicology and pharmacology : RTP 2007;49(3):208-16.
2007: Papeleu P; Wullaert A; Elaut G; Henkens T; Vinken M; Laus G; Tourwé D; Beyaert R; Rogiers V; Vanhaecke T
Inhibition of NF-kappaB activation by the histone deacetylase inhibitor 4-Me2N-BAVAH induces an early G1 cell cycle arrest in primary hepatocytes.
Cell proliferation 2007;40(5):640-55.
2007: Henkens Tom; Vinken Mathieu; Vanhaecke Tamara; Rogiers Vera
Modulation of CYP1A1 and CYP2B1 expression upon cell cycle progression in cultures of primary rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(7):1253-7.
2007: Snykers Sarah; De Kock Joery; Vanhaecke Tamara; Rogiers Vera
Differentiation of neonatal rat epithelial cells from biliary origin into immature hepatic cells by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(7):1325-31.
2007: Snykers Sarah; Vinken Mathieu; Rogiers Vera; Vanhaecke Tamara
Differential role of epigenetic modulators in malignant and normal stem cells: a novel tool in preclinical in vitro toxicology and clinical therapy.
Archives of toxicology 2007;81(8):533-44.
2007: Vinken Mathieu; Henkens Tom; Snykers Sarah; Lukaszuk Aneta; Tourwé Dirk; Rogiers Vera; Vanhaecke Tamara
The novel histone deacetylase inhibitor 4-Me2N-BAVAH differentially affects cell junctions between primary hepatocytes.
Toxicology 2007;236(1-2):92-102.
2007: Elaut G; Laus G; Alexandre E; Richert L; Bachellier P; Tourwé D; Rogiers V; Vanhaecke T
A metabolic screening study of trichostatin A (TSA) and TSA-like histone deacetylase inhibitors in rat and human primary hepatocyte cultures.
The Journal of pharmacology and experimental therapeutics 2007;321(1):400-8.
2007: Henkens Tom; Papeleu Peggy; Elaut Greetje; Vinken Mathieu; Rogiers Vera; Vanhaecke Tamara
Trichostatin A, a critical factor in maintaining the functional differentiation of primary cultured rat hepatocytes.
Toxicology and applied pharmacology 2007;218(1):64-71.
2007: Elaut Greetje; Rogiers Vera; Vanhaecke Tamara
The pharmaceutical potential of histone deacetylase inhibitors.
Current pharmaceutical design 2007;13(25):2584-620.
2007: Snykers Sarah; Vanhaecke Tamara; De Becker Ann; Papeleu Peggy; Vinken Mathieu; Van Riet Ivan; Rogiers Vera
Chromatin remodeling agent trichostatin A: a key-factor in the hepatic differentiation of human mesenchymal stem cells derived of adult bone marrow.
BMC developmental biology 2007;7():24.
2007: Houben E; Uchida Y; Nieuwenhuizen W F; De Paepe K; Vanhaecke T; Holleran W M; Rogiers V
Kinetic characteristics of acidic and alkaline ceramidase in human epidermis.
Skin pharmacology and physiology 2007;20(4):187-94.
2007: Houben E; De Paepe K; Rogiers V
A keratinocyte's course of life.
Skin pharmacology and physiology 2007;20(3):122-32.
2006: Snykers Sarah; Vanhaecke Tamara; Papeleu Peggy; Luttun Aernout; Jiang Yuehua; Vander Heyden Yvan; Verfaillie Catherine; Rogiers Vera
Sequential exposure to cytokines reflecting embryogenesis: the key for in vitro differentiation of adult bone marrow stem cells into functional hepatocyte-like cells.
Toxicological sciences : an official journal of the Society of Toxicology 2006;94(2):330-41; discussion 235-9.
2006: Elaut Greetje; Henkens Tom; Papeleu Peggy; Snykers Sarah; Vinken Mathieu; Vanhaecke Tamara; Rogiers Vera
Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures.
Current drug metabolism 2006;7(6):629-60.
2006: Vinken Mathieu; Henkens Tom; Vanhaecke Tamara; Papeleu Peggy; Geerts Albert; Van Rossen Elke; Chipman James Kevin; Meda Paolo; Rogiers Vera
Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes.
Toxicological sciences : an official journal of the Society of Toxicology 2006;91(2):484-92.
2006: Houben Evi; De Paepe Kristien; Rogiers Vera
Skin condition associated with intensive use of alcoholic gels for hand disinfection: a combination of biophysical and sensorial data.
Contact dermatitis 2006;54(5):261-7.
2006: Houben Evi; Holleran Walter M; Yaginuma Toshiaki; Mao Cungui; Obeid Lina M; Rogiers Vera; Takagi Yutaka; Elias Peter M; Uchida Yoshikazu
Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis.
Journal of lipid research 2006;47(5):1063-70.
2006: Vinken Mathieu; Vanhaecke Tamara; Papeleu Peggy; Snykers Sarah; Henkens Tom; Rogiers Vera
Connexins and their channels in cell growth and cell death.
Cellular signalling 2006;18(5):592-600.
2006: Vinken Mathieu; Papeleu Peggy; Snykers Sarah; De Rop Evelien; Henkens Tom; Chipman James Kevin; Rogiers Vera; Vanhaecke Tamara
Involvement of cell junctions in hepatocyte culture functionality.
Critical reviews in toxicology 2006;36(4):299-318.
2006: Vinken Mathieu; Vanhaecke Tamara; Papeleu Peggy; Snykers Sarah; Henkens Tom; Elaut Greetje; Chipman James Kevin; Rogiers Vera
A study of connexin expression in monolayer cultures of primary rat hepatocytes.
ALTEX : Alternativen zu Tierexperimenten 2006;23 Suppl():456-60.
2006: Vanhaecke Tamara; Vinken Mathieu; Henkens Tom; Snykers Sarah; Elaut Greetje; Papeleu Peggy; Rogiers Vera
Effects of Trichostatin A on Apoptosis-regulating Proteins During Hepatocyte Isolation.
ALTEX : Alternativen zu Tierexperimenten 2006;23 Suppl():441-4.
2006: Snykers Sarah; Vanhaecke Tamara; Papeleu Peggy; Henkens Tom; Vinken Mathieu; Elaut Greetje; Van Riet Ivan; Rogiers Vera
In vitro multipotency of human bone marrow (mesenchymal) stem cells.
ALTEX : Alternativen zu Tierexperimenten 2006;23 Suppl():400-5.
2006: Snykers Sarah; Vanhaecke Tamara; Rogiers Vera
Isolation of rat bone marrow stem cells.
Methods in molecular biology (Clifton, N.J.) 2006;320():265-72.
2006: Elaut Greetje; Papeleu Peggy; Vinken Mathieu; Henkens Tom; Snykers Sarah; Vanhaecke Tamara; Rogiers Vera
Hepatocytes in suspension.
Methods in molecular biology (Clifton, N.J.) 2006;320():255-63.
2006: Vinken Mathieu; Elaut Greetje; Henkens Tom; Papeleu Peggy; Snykers Sarah; Vanhaecke Tamara; Rogiers Vera
Rat hepatocyte cultures: collagen gel sandwich and immobilization cultures.
Methods in molecular biology (Clifton, N.J.) 2006;320():247-54.
2006: Henkens Tom; Vanhaecke Tamara; Papeleu Peggy; Elaut Greetje; Vinken Mathieu; Snykers Sarah; Rogiers Vera
Rat hepatocyte cultures: conventional monolayer and cocultures with rat liver epithelial cells.
Methods in molecular biology (Clifton, N.J.) 2006;320():239-46.
2006: Papeleu Peggy; Vanhaecke Tamara; Henkens Tom; Elaut Greetje; Vinken Mathieu; Snykers Sarah; Rogiers Vera
Isolation of rat hepatocytes.
Methods in molecular biology (Clifton, N.J.) 2006;320():229-37.
2006: Vanhaecke Tamara; Rogiers Vera
Hepatocyte cultures in drug metabolism and toxicological research and testing.
Methods in molecular biology (Clifton, N.J.) 2006;320():209-27.
2005: Barel A; Calomme M; Timchenko A; De Paepe K; Demeester N; Rogiers V; Clarys P; Vanden Berghe D
Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin.
Archives of dermatological research 2005;297(4):147-53.
2005: Hachem Jean-Pierre; Man Mao-Quiang; Crumrine Debra; Uchida Yoshikazu; Brown Barbara E; Rogiers Vera; Roseeuw Diane; Feingold Kenneth R; Elias Peter M
Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity.
The Journal of investigative dermatology 2005;125(3):510-20.
2005: Coecke Sandra; Blaauboer Bas J; Elaut Greetje; Freeman Stuart; Freidig Andreas; Gensmantel Nigel; Hoet Peter; Kapoulas Vassilios M; Ladstetter Bernhard; Langley Gill; Leahy David; Mannens Geert; Meneguz Annarita; Monshouwer Mario; Nemery Ben; Pelkonen Olavi; Pfaller Walter; Prieto Pilar; Proctor Nick; Rogiers Vera; Rostami-Hodjegan Amin; Sabbioni Enrico; Steiling Winfried; van de Sandt Johannes J M
Toxicokinetics and metabolism.
Alternatives to laboratory animals : ATLA 2005;33 Suppl 1():147-75.
2005: Diembeck Walter; Eskes Chantra; Heylings Jon R; Langley Gill; Rogiers Vera; van de Sandt Johannes J M; Zuang Valérie
Skin absorption and penetration.
Alternatives to laboratory animals : ATLA 2005;33 Suppl 1():105-7.
2005: Elaut Greetje; Vanhaecke Tamara; Heyden Yvan Vander; Rogiers Vera
Spontaneous apoptosis, necrosis, energy status, glutathione levels and biotransformation capacities of isolated rat hepatocytes in suspension: effect of the incubation medium.
Biochemical pharmacology 2005;69(12):1829-38.
2005: Papeleu Peggy; Vanhaecke Tamara; Elaut Greetje; Vinken Mathieu; Henkens Tom; Snykers Sarah; Rogiers Vera
Differential effects of histone deacetylase inhibitors in tumor and normal cells-what is the toxicological relevance?
Critical reviews in toxicology 2005;35(4):363-78.
2005: De Paepe Kristien; Houben Evi; Adam Ralf; Wiesemann Frank; Rogiers Vera
Validation of the VapoMeter, a closed unventilated chamber system to assess transepidermal water loss vs. the open chamber Tewameter.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2005;11(1):61-9.
2004: Vanhaecke Tamara; Henkens Tom; Kass George E N; Rogiers Vera
Effect of the histone deacetylase inhibitor trichostatin A on spontaneous apoptosis in various types of adult rat hepatocyte cultures.
Biochemical pharmacology 2004;68(4):753-60.
2004: Vanhaecke Tamara; Papeleu Peggy; Elaut Greetje; Rogiers Vera
Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view.
Current medicinal chemistry 2004;11(12):1629-43.
2004: De Paepe K; Weerheim A; Houben E; Roseeuw D; Ponec M; Rogiers V
Analysis of epidermal lipids of the healthy human skin: factors affecting the design of a control population.
Skin pharmacology and physiology 2004;17(1):23-30.
2003: Vinken M; Vanhaecke T; Rogiers V
[The role of intercellular communication via "gap junctions" in disease]
Nederlands tijdschrift voor geneeskunde 2003;147(50):2463-6.
2003: Papeleu Peggy; Loyer Pascal; Vanhaecke Tamara; Elaut Greetje; Geerts Albert; Guguen-Guillouzo Christiane; Rogiers Vera
Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes.
Journal of hepatology 2003;39(3):374-82.
2003: Van Ommeslaeghe K; Elaut G; Brecx V; Papeleu P; Iterbeke K; Geerlings P; Tourwé D; Rogiers V
Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition.
Bioorganic & medicinal chemistry letters 2003;13(11):1861-4.
2003: Hellemans Karine; Rombouts Krista; Quartier Erik; Dittié Andrea S; Knorr Andreas; Michalik Liliane; Rogiers Vera; Schuit Frans; Wahli Walter; Geerts Andrea
PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation.
Journal of lipid research 2003;44(2):280-95.
2003: Depreter Marianne; Walker Tracy; Beken Sonja; De Smet Karen; Papeleu Peggy; Tytgat Tom; Espeel Marc; Rogiers Vera; Roels Frank
Modified peroxisomes in primary hepatocyte cultures.
Advances in experimental medicine and biology 2003;544():255-64.
2002: Rogiers Vera
ecopa: a powerful concept in the way forward for alternative methods.
Alternatives to laboratory animals : ATLA 2002;30 Suppl 2():199-202.
2002: Elaut G; Török G; Vinken M; Laus G; Papeleu P; Tourwe D; Rogiers V
Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(12):1320-8.
2002: De Paepe K; Roseeuw D; Rogiers V
Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids.
Journal of the European Academy of Dermatology and Venereology : JEADV 2002;16(6):587-94.
2002: Hachem Jean Pierre; De Paepe Kristien; Sterckx Guy; Kaufman Leonard; Rogiers Vera; Roseeuw Diane
Evaluation of biophysical and clinical parameters of skin barrier function among hospital workers.
Contact dermatitis 2002;46(4):220-3.
2002: Depreter Marianne; Walker Tracy; De Smet Karen; Beken Sonja; Kerckaert Ingrid; Rogiers Vera; Roels Frank
Hepatocyte polarity and the peroxisomal compartment: a comparative study.
The Histochemical journal 2002;34(3-4):139-51.
2002: Hachem Jean-Pierre; De Paepe Kristien; Vanpee Els; Kaufman Leonard; Rogiers Vera; Roseeuw Diane
The effect of two moisturisers on skin barrier damage in allergic contact dermatitis.
European journal of dermatology : EJD 2002;12(2):136-8.
2002: Hachem J P; De Paepe K; Vanpée E; Bogaerts M; Kaufman L; Rogiers V; Roseeuw D
Efficacy of topical corticosteroids in nickel-induced contact allergy.
Clinical and experimental dermatology 2002;27(1):47-50.
2002: De Paepe Kristien; Hachem Jean-Pierre; Vanpee Els; Roseeuw Diane; Rogiers Vera
Effect of rice starch as a bath additive on the barrier function of healthy but SLS-damaged skin and skin of atopic patients.
Acta dermato-venereologica 2002;82(3):184-6.
2001: Vanhaecke T; Elaut G; Rogiers V
Effect of oxygen concentration on the expression of glutathione S-transferase activity in periportal and perivenous rat hepatocyte cultures.
Toxicology in vitro : an international journal published in association with BIBRA 2001;15(4-5):387-92.
2001: De Paepe K; Janssens K; Hachem J P; Roseeuw D; Rogiers V
Squamometry as a screening method for the evaluation of hydrating products.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2001;7(3):184-92.
2001: De Paépe K; Hachem J P; Vanpee E; Goossens A; Germaux M A; Lachapelle J M; Lambert J; Matthieu L; Roseeuw D; Suys E; Van Hecke E; Rogiers V
Beneficial effects of a skin tolerance-tested moisturizing cream on the barrier function in experimentally-elicited irritant and allergic contact dermatitis.
Contact dermatitis 2001;44(6):337-43.
2001: Vanhaecke T; Foriers A; Geerts A; Shephard E A; Vercruysse A; Rogiers V
Pyruvate-induced long-term maintenance of glutathione s-transferase in rat hepatocyte cultures.
Alternatives to laboratory animals : ATLA 2001;29(3):335-46.
2001: De Smet K; Loyer P; Gilot D; Vercruysse A; Rogiers V; Guguen-Guillouzo C
Effects of epidermal growth factor on CYP inducibility by xenobiotics, DNA replication, and caspase activations in collagen I gel sandwich cultures of rat hepatocytes.
Biochemical pharmacology 2001;61(10):1293-303.
2001: Slaus K; Coughtrie M W; Sharp S; Vanhaecke T; Vercruysse A; Rogiers V
Influence of culture system and medium enrichment on sulfotransferase and sulfatase expression in male rat hepatocyte cultures.
Biochemical pharmacology 2001;61(9):1107-17.
2001: Vanhaecke T; Derde M P; Vercruysse A; Rogiers V
Hydroxypropyl-beta-cyclodextrin as delivery system for thyroid hormones, regulating glutathione S-transferase expression in rat hepatocyte co-cultures.
Biochemical pharmacology 2001;61(9):1073-8.
2001: Rogiers V;
EEMCO guidance for the assessment of transepidermal water loss in cosmetic sciences.
Skin pharmacology and applied skin physiology 2001;14(2):117-28.
2001: De Smet K; Cavin C; Vercruysse A; Rogiers V
Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes.
Alternatives to laboratory animals : ATLA 2001;29(2):179-92.
2001: Beken S; De Smet K; Depreter M; Roels F; Vercruysse A; Rogiers V
Effects of L-proline on phase I and phase II xenobiotic biotransformation capacities of rat and human hepatocytes in long-term collagen gel cultures.
Alternatives to laboratory animals : ATLA 2001;29(1):35-53.
2001: Vanhaecke T; Lindros K O; Oinonen T; Vercruysse A; Rogiers V
Triiodothyronine downregulates the periportal expression of alpha class glutathione S-transferase in rat liver.
FEBS letters 2001;487(3):356-60.
2001: Hachem J P; De Paepe K; Vanpée E; Kaufman L; Rogiers V; Roseeuw D
Combination therapy improves the recovery of the skin barrier function: an experimental model using a contact allergy patch test combined with TEWL measurements.
Dermatology (Basel, Switzerland) 2001;202(4):314-9.
2000: De Smet K; Brüning T; Blaszkewicz M; Bolt H M; Vercruysse A; Rogiers V
Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes.
Archives of toxicology 2000;74(10):587-92.
2000: Vanhaecke T; Lindros K O; Oinonen T; Vercruysse A; Rogiers V
Effect of long-term ethanol exposure on the acinar distribution of hepatic glutathione S-transferase.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(12):1470-4.
2000: Vanhaecke T; Lindros K O; Oinonen T; Coecke S; DeBast G; Phillips I R; Shephard E A; Vercruysse A; Rogiers V
Effect of ethanol on the expression of hepatic glutathione S-transferase: an in vivo/in vitro study.
Biochemical pharmacology 2000;60(10):1491-6.
2000: De Paepe K; Lagarde J M; Gall Y; Roseeuw D; Rogiers V
Microrelief of the skin using a light transmission method.
Archives of dermatological research 2000;292(10):500-10.
2000: Coecke S; Vanhaecke T; Foriers A; Phillips I R; Vercruysse A; Shephard E A; Rogiers V
Hormonal regulation of glutathione S-transferase expression in co-cultured adult rat hepatocytes.
The Journal of endocrinology 2000;166(2):363-71.
2000: De Paepe K; Derde M P; Roseeuw D; Rogiers V
Incorporation of ceramide 3B in dermatocosmetic emulsions: effect on the transepidermal water loss of sodium lauryl sulphate-damaged skin.
Journal of the European Academy of Dermatology and Venereology : JEADV 2000;14(4):272-9.
2000: de Paepe K; Derde M P; Roseeuw D; Rogiers V
Claim substantiation and efficiency of hydrating body lotions and protective creams.
Contact dermatitis 2000;42(4):227-34.
2000: Depreter M; Tytgat T; Beken S; Espeel M; De Smet K; Rogiers V; Roels F
Effects of extracellular matrix on the expression of peroxisomes in primary rat hepatocyte cultures.
Journal of hepatology 2000;32(3):381-91.
1999: De Bleser P J; Xu G; Rombouts K; Rogiers V; Geerts A
Glutathione levels discriminate between oxidative stress and transforming growth factor-beta signaling in activated rat hepatic stellate cells.
The Journal of biological chemistry 1999;274(48):33881-7.
1999: Niki T; Rombouts K; De Bleser P; De Smet K; Rogiers V; Schuppan D; Yoshida M; Gabbiani G; Geerts A
A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture.
Hepatology (Baltimore, Md.) 1999;29(3):858-67.
1999: Geerts A; Rogiers V
Sho-saiko-To: the right blend of traditional Oriental medicine and liver cell biology.
Hepatology (Baltimore, Md.) 1999;29(1):282-4.
1998: Coecke S; Debast G; Phillips I R; Vercruysse A; Shephard E A; Rogiers V
Hormonal regulation of microsomal flavin-containing monooxygenase activity by sex steroids and growth hormone in co-cultured adult male rat hepatocytes.
Biochemical pharmacology 1998;56(8):1047-51.
1998: Vanhaecke T; De Smet K; Beken S; Pauwels M; Vercruysse A; Rogiers V
Rat hepatocyte cultures. Conventional monolayer cultures and cocultures with rat liver epithelial cells.
Methods in molecular biology (Clifton, N.J.) 1998;107():311-7.
1998: Beken S; Vanhaecke T; De Smet K; Pauwels M; Vercruysse A; Rogiers V
Collagen-gel cultures of rat hepatocytes: collagen-gel sandwich and immobilization cultures.
Methods in molecular biology (Clifton, N.J.) 1998;107():303-9.
1998: De Smet K; Beken S; Vanhaecke T; Pauwels M; Vercruysse A; Rogiers V
Isolation of rat hepatocytes.
Methods in molecular biology (Clifton, N.J.) 1998;107():295-301.
1998: Rogiers V; Vercruysse A
Hepatocyte cultures in drug metabolism and toxicological research and testing.
Methods in molecular biology (Clifton, N.J.) 1998;107():279-94.
1997: De Bleser P J; Niki T; Xu G; Rogiers V; Geerts A
Localization and cellular sources of activins in normal and fibrotic rat liver.
Hepatology (Baltimore, Md.) 1997;26(4):905-12.
1997: Xu G; Niki T; Virtanen I; Rogiers V; De Bleser P; Geerts A
Gene expression and synthesis of fibronectin isoforms in rat hepatic stellate cells. Comparison with liver parenchymal cells and skin fibroblasts.
The Journal of pathology 1997;183(1):90-8.
1997: Cornet M; Rogiers V
Metabolism and toxicity of 2-methylpropene (isobutene)--a review.
Critical reviews in toxicology 1997;27(3):223-32.
1997: De Bleser P J; Niki T; Rogiers V; Geerts A
Transforming growth factor-beta gene expression in normal and fibrotic rat liver.
Journal of hepatology 1997;26(4):886-93.
1997: Rogiers V; Vandenberghe Y; Vanhaecke T; Geerts A; Callaerts A; Carleer J; Roba J; Vercruysse A
Observation of hepatotoxic effects of 2-n-pentylaminoacetamide (Milacemide) in rat liver by a combined in vivo/in vitro approach.
Archives of toxicology 1997;71(5):271-82.
1995: Cornet M; Callaerts A; Jorritsma U; Bolt H; Vercruysse A; Rogiers V
Species-dependent differences in biotransformation pathways of 2-methylpropene (isobutene).
Chemical research in toxicology 1995;8(7):987-92.
1995: Rogiers V; Akrawi M; Vercruysse A; Phillips I R; Shephard E A
Effects of the anticonvulsant, valproate, on the expression of components of the cytochrome-P-450-mediated monooxygenase system and glutathione S-transferases.
European journal of biochemistry / FEBS 1995;231(2):337-43.
1995: de Bleser P J; Jannes P; van Buul-Offers S C; Hoogerbrugge C M; van Schravendijk C F; Niki T; Rogiers V; van den Brande J L; Wisse E; Geerts A
Insulinlike growth factor-II/mannose 6-phosphate receptor is expressed on CCl4-exposed rat fat-storing cells and facilitates activation of latent transforming growth factor-beta in cocultures with sinusoidal endothelial cells.
Hepatology (Baltimore, Md.) 1995;21(5):1429-37.
1995: Jorritsma U; Cornet M; Van Hummelen P; Bolt H M; Vercruysse A; Kirsch-Volders M; Rogiers V
Comparative mutagenicity of 2-methylpropene (isobutene), its epoxide 2-methyl-1,2-epoxypropane and propylene oxide in the in vitro micronucleus test using human lymphocytes.
Mutagenesis 1995;10(2):101-4.
1995: Cornet M; Callaerts A; Vercruysse A; Rogiers V
In vitro biotransformation of 2-methylpropene (isobutene) in rat lung tissue in comparison with liver tissue.
Archives of toxicology 1995;70(1):64-7.
1994: Akrawi M; Rogiers V; Vercruysse A; Phillips I R; Shephard E A
Long-term preservation and induction of drug metabolizing enzymes in co-cultured rat hepatocytes.
Biochemical Society transactions 1994;22(2):124S.
1994: Cornet M; Mertens K; Callaerts A; Sonck W; Vercruysse A; Rogiers V
Age- and gender-related changes in the hepatic metabolism of 2-methylpropene and relationship to epoxide metabolizing enzymes.
Mechanisms of ageing and development 1994;74(1-2):103-15.
1994: Leutbecher M; Cornet M; Rogiers V; Bolt H M; Regier S [corrected to Rogiers V ]
DNA binding study with inhaled [14C]2-methylpropene (isobutene)
Archives of toxicology 1994;68(1):71-2.
1993: Rogiers V; Vercruysse A
Rat hepatocyte cultures and co-cultures in biotransformation studies of xenobiotics.
Toxicology 1993;82(1-3):193-208.
1993: Castelain P; Criado B; Cornet M; Laib R; Rogiers V; Kirsch-Volders M
Comparative mutagenicity of structurally related aliphatic epoxides in a modified Salmonella/microsome assay.
Mutagenesis 1993;8(5):387-93.
1993: Geerts A; Greenwel P; Cunningham M; De Bleser P; Rogiers V; Wisse E; Rojkind M
Identification of connective tissue gene transcripts in freshly isolated parenchymal, endothelial, Kupffer and fat-storing cells by northern hybridization analysis.
Journal of hepatology 1993;19(1):148-58.
1993: Akrawi M; Rogiers V; Vandenberghe Y; Palmer C N; Vercruysse A; Shephard E A; Phillips I R
Maintenance and induction in co-cultured rat hepatocytes of components of the cytochrome P450-mediated mono-oxygenase.
Biochemical pharmacology 1993;45(8):1583-91.
1993: Mertens K; Rogiers V; Vercruysse A
Glutathione dependent detoxication in adult rat hepatocytes under various culture conditions.
Archives of toxicology 1993;67(10):680-5.
1992: Vandenberghe Y; Tee L; Rogiers V; Yeoh G
Transcriptional- and post-transcriptional-dependent regulation of glutathione S-transferase expression in rat hepatocytes as a function of culture conditions.
FEBS letters 1992;313(2):155-9.
1992: Coecke S; Mertens K; Segaert A; Callaerts A; Vercruysse A; Rogiers V
Spectrophotometric measurement of flavin-containing monooxygenase activity in freshly isolated rat hepatocytes and their cultures.
Analytical biochemistry 1992;205(2):285-8.
1992: Rogiers V; Callaerts A; Vercruysse A; Akrawi M; Shephard E; Phillips I
Effects of valproate on xenobiotic biotransformation in rat liver. In vivo and in vitro experiments.
Pharmaceutisch weekblad. Scientific edition 1992;14(3A):127-31.
1992: Cornet M; Castelain P; Vercruysse A; Laib R; Kirsch-Volders M; Rogiers V
Mutagenicity of 2-methylpropene (isobutene) and its epoxide in a modified Salmonella assay for volatile compounds.
Mutation research 1992;271(3):213-21.
1992: Rogiers V; Akrawi M; Vandenberghe Y; Shephard E; Phillips I; Vercruysse A
Co-cultures of rat hepatocytes in the study of valproate toxicity.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1992;15():156-9.
1991: Rogiers V; Coecke S; Vandenberghe Y; Morel F; Callaerts A; Verleye G; Van Bezooijen C F; Guillouzo A; Vercruysse A
Effect of the aging process on the gender and phenobarbital dependent expression of glutathione S-transferase subunits in brown Norway rat liver.
Biochemical pharmacology 1991;42(3):491-8.
1991: Vandenberghe Y; Tee L; Morel F; Rogiers V; Guillouzo A; Yeoh G
Regulation of glutathione S-transferase gene expression by phenobarbital in cultured adult rat hepatocytes.
FEBS letters 1991;284(1):103-8.
1991: Mertens K; Rogiers V; Sonck W; Vercruysse A
Measurement of reduced and oxidized glutathione in cultures of adult rat hepatocytes.
Journal of chromatography 1991;565(1-2):149-57.
1991: Mertens K; Rogiers V; Sonck W; Vercruysse A
Reduced and oxidized glutathione contents in adult rat hepatocytes under various culture conditions.
Cell biology and toxicology 1991;7(2):101-10.
1991: Csanády G A; Freise D; Denk B; Filser J G; Cornet M; Rogiers V; Laib R J
Investigation of species differences in isobutene (2-methylpropene) metabolism between mice and rats.
Archives of toxicology 1991;65(2):100-5.
1991: Cornet M; Sonck W; Callaerts A; Csanády G; Vercruysse A; Laib R J; Rogiers V
In vitro biotransformation of 2-methylpropene (isobutene): epoxide formation in mice liver.
Archives of toxicology 1991;65(4):263-7.
1990: Rogiers V; Vandenberghe Y; Callaerts A; Verleye G; Cornet M; Mertens K; Sonck W; Vercruysse A
Phase I and phase II xenobiotic biotransformation in cultures and co-cultures of adult rat hepatocytes.
Biochemical pharmacology 1990;40(8):1701-6.
1990: Coecke S; Vandenberghe Y; Callaerts A; Sonck W; Verleye G; Van Bezooijen C F; Vercruysse A; Rogiers V
Hepatic cytosolic glutathione S-transferase activities in ageing brown Norway rats--importance of sex differences and phenobarbital treatment for studies of ageing.
Mechanisms of ageing and development 1990;55(2):189-98.
1990: Vandenberghe Y; Morel F; Pemble S; Taylor J B; Rogiers V; Ratanasavanh D; Vercruysse A; Ketterer B; Guillouzo A
Changes in expression of mRNA coding for glutathione S-transferase subunits 1-2 and 7 in cultured rat hepatocytes.
Molecular pharmacology 1990;37(3):372-6.
1990: Vandenberghe Y; Foriers A; Rogiers V; Vercruysse A
Changes in expression and "de novo" synthesis of glutathione S-transferase subunits in cultured adult rat hepatocytes.
Biochemical pharmacology 1990;39(4):685-90.
1989: Morel F; Vandenberghe Y; Pemble S; Taylor J B; Ratanasavanh D; Rogiers V; Ketterer B; Guillouzo A
Regulation of glutathione S-transferase subunits 3 and 4 in cultured rat hepatocytes.
FEBS letters 1989;258(1):99-102.
1989: Vandenberghe Y; Morel F; Foriers A; Ketterer B; Vercruysse A; Guillouzo A; Rogiers V
Effect of phenobarbital on the expression of glutathione S-transferase isoenzymes in cultured rat hepatocytes.
FEBS letters 1989;251(1-2):59-64.
1988: Rogiers V; Vandenberghe Y; Callaerts A; Sonck W; Maes V; Vercruysse A
The inducing and inhibiting effects of sodium valproate in vivo on the biotransformation systems of xenobiotics in isolated rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1988;18(6):665-73.
1987: Rogiers V; Paeme G; Sonck W; Vercruysse A
Metabolism of procyclidine in isolated rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1987;17(7):849-57.
1986: Rogiers V; Adriaenssens L; Vandenberghe Y; Gepts E; Callaerts A; Vercruysse A
Critical evaluation of 7-ethoxycoumarin O-deethylase activity measurement in intact isolated rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1986;16(9):817-26.
1985: Rogiers V; Vandenberghe Y; Vercruysse A
Inhibition of gluconeogenesis by sodium valproate and its metabolites in isolated rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1985;15(8-9):759-65.

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