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Vera Rogiers

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Eva Ramboer; Vera Rogiers; Tamara Vanhaecke; Mathieu Vinken
Primary hepatocyte cultures as prominent in vitro tools to study hepatic drug transporters.
Mathieu Vinken; Erwin Witters; An Staes; Dirk Valkenborg; Tamara Vanhaecke; Rachel Cavill; Bruno Cogliati; Maria Lúcia Zaidan Dagli; Elke Decrock; Timothy M D Ebbels; James K Ellis; Kris Gevaert; Hector C Keun; Luc Leybaert; Michaël Maes; Gustavo B Menezes; André G Oliveira; Vera Rogiers
Proteomic and metabolomic responses to connexin43 silencing in primary hepatocyte cultures.
J Fraczek; Vera Rogiers; Tamara Vanhaecke; J Bolleyn; Mathieu Vinken
Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.

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All Publications

2013: Eva Ramboer; Vera Rogiers; Tamara Vanhaecke; Mathieu Vinken
Primary hepatocyte cultures as prominent in vitro tools to study hepatic drug transporters.
Drug metabolism reviews 2013;45(2):196-217.
2013: Mathieu Vinken; Erwin Witters; An Staes; Dirk Valkenborg; Tamara Vanhaecke; Rachel Cavill; Bruno Cogliati; Maria Lúcia Zaidan Dagli; Elke Decrock; Timothy M D Ebbels; James K Ellis; Kris Gevaert; Hector C Keun; Luc Leybaert; Michaël Maes; Gustavo B Menezes; André G Oliveira; Vera Rogiers
Proteomic and metabolomic responses to connexin43 silencing in primary hepatocyte cultures.
Archives of toxicology 2013;87(5):883-94.
2013: J Fraczek; Vera Rogiers; Tamara Vanhaecke; J Bolleyn; Mathieu Vinken
Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.
Archives of toxicology 2013;87(4):577-610.
2013: Nan Wang; Joris Wauman; Kerstin Boengler; Mélissa Bol; Feliksas F Bukauskas; Geert Bultynck; Manuelle De Bock; Elke De Vuyst; Elke Decrock; W Howard Evans; Gerd Heusch; Charles P Lai; Christian C Naus; Nicolás Palacios-Prado; Raf Ponsaerts; Vera Rogiers; Rainer Schulz; Karin R Sipido; Jan Tavernier; Mathieu Vinken; Luc Leybaert
Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury.
Basic research in cardiology 2013;108(1):309.
2013: Nan Wang; Vera Rogiers; Mathieu Vinken; Mélissa Bol; Feliksas F Bukauskas; Geert Bultynck; Manuelle De Bock; Elke Decrock; Ashish Gadicherla; Luc Leybaert
Paracrine signaling through plasma membrane hemichannels.
Biochimica et biophysica acta 2013;1828(1):35-50.
2012: Joery De Kock; John Antonydas Gaspar; Olivier Govaere; Laurence Lagneaux; Kesavan Meganathan; Mehdi Najar; Gordana Raicevic; Robim M Rodrigues; Feras Al Battah; Jennifer Bolleyn; Steven Branson; Karolien Buyl; Tania Roskams; Agapios Sachinidis; Tamara Vanhaecke; Vera Rogiers
Mesoderm-derived stem cells: the link between the transcriptome and their differentiation potential.
Stem cells and development 2012;21(18):3309-23.
2012: Tatyana Y Doktorova; Heidrun Ellinger-Ziegelbauer; Jos Kleinjans; Joost van Delft; Tamara Vanhaecke; Mathieu Vinken; Hans-Jürgen Ahr; Vera Rogiers
Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.
Archives of toxicology 2012;86(11):1703-15.
2012: Tatyana Y Doktorova; Heidrun Ellinger-Ziegelbauer; Jos Kleinjans; Joost van Delft; Tamara Vanhaecke; Mathieu Vinken; Hans-Jürgen Ahr; Vera Rogiers
Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.
Archives of toxicology 2012;86(9):1399-411.
2012: Mathieu Vinken; Tamara Vanhaecke; Bruno Cogliati; Maria Lúcia Zaidan Dagli; Joery De Kock; Gustavo B Menezes; André G Oliveira; Vera Rogiers
Modifications in connexin expression in liver development and cancer.
Cell communication & adhesion 2012;19(3-4):55-62.
2012: Mathieu Vinken; Tamara Vanhaecke; Geert Bultynck; Elke Decrock; Bernard Himpens; Luc Leybaert; Vera Rogiers
Non-channel functions of connexins in cell growth and cell death.
Biochimica et biophysica acta 2012;1818(8):2002-8.
2012: Joanna Edyta Fraczek; Dirk Tourwé; Tamara Vanhaecke; Mathieu Vinken; Vera Rogiers
Synergetic effects of DNA demethylation and histone deacetylase inhibition in primary rat hepatocytes.
Investigational new drugs 2012;30(4):1715-24.
2012: Elke Decrock; C Erneux; A Kaczmarek; Dmitri V Krysko; M Bol; Geert Bultynck; G Crispino; Manuelle De Bock; Elke De Vuyst; F Mammano; Christian C Naus; Vera Rogiers; Peter Vandenabeele; Mathieu Vinken; N Wang; Luc Leybaert
Transfer of IP₃ through gap junctions is critical, but not sufficient, for the spread of apoptosis.
Cell death and differentiation 2012;19(6):947-57.
2012: Mathieu Vinken; Tamara Vanhaecke; Vera Rogiers
Primary hepatocyte cultures as in vitro tools for toxicity testing: quo vadis?
Toxicology in vitro : an international journal published in association with BIBRA 2012;26(3):541-4.
2012: Mathieu Vinken; Manon Vivier; Gamze Ates; Marleen Pauwels; Tamara Vanhaecke; Vera Rogiers
Screening of repeated dose toxicity data present in SCC(NF)P/SCCS safety evaluations of cosmetic ingredients.
Archives of toxicology 2012;86(3):405-12.
2012: Tatyana Y Doktorova; Marleen Pauwels; Tamara Vanhaecke; Mathieu Vinken; Vera Rogiers
Opportunities for an alternative integrating testing strategy for carcinogen hazard assessment?
Critical reviews in toxicology 2012;42(2):91-106.
2012: Laurent Dollé; Christophe Empsen; Albert Geerts; Isabelle A Leclercq; Jie Mei; Mustapha Najimi; Philip Roelandt; Vera Rogiers; Sarah Snykers; Etienne Sokal; Konrad Streetz; Neil Theise; Feras Al Battah; Jan Best; Elke Van Rossen; Catherine Verfaillie; Leo van Grunsven
Successful isolation of liver progenitor cells by aldehyde dehydrogenase activity in naïve mice.
Hepatology (Baltimore, Md.) 2012;55(2):540-52.
2012: J De Kock; J A Gaspar; S Jagtap; Agapios Sachinidis; Sarah Snykers; Tamara Vanhaecke; S Branson; Vera Rogiers
A liver-derived rat epithelial cell line from biliary origin acquires hepatic functions upon sequential exposure to hepatogenic growth factors and cytokines.
Current medicinal chemistry 2012;19(26):4523-33.
2011: Mathieu Vinken; Tamara Vanhaecke; Elke De Vuyst; Elke Decrock; Tatyana Doktorova; Luc Leybaert; Eva Ramboer; Vera Rogiers
Characterization of spontaneous cell death in monolayer cultures of primary hepatocytes.
Archives of toxicology 2011;85(12):1589-96.
2011: Liesbeth Ceelen; Freddy Haesebrouck; Vera Rogiers; Tamara Vanhaecke; Mathieu Vinken
Modulation of connexin signaling by bacterial pathogens and their toxins.
Cellular and molecular life sciences : CMLS 2011;68(18):3047-64.
2011: Marijke De Bock; Gaspard De Ley; Elke De Vuyst; Elke Decrock; Geneviève Dupont; William Howard Evans; Mélissa Bol; Geert Bultynck; Romeo Cecchelli; Maxime Culot; Anaelle da Costa; Ine Dauwe; Vera Rogiers; Alexander M Simon; Mathieu Vinken; Nan Wang; Luc Leybaert
Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(9):1942-57.
2011: Feras Al Battah; Joery De Kock; Anja Heymans; Eva Ramboer; Vera Rogiers; Tamara Vanhaecke; Sarah Snykers
Evaluation of the multipotent character of human adipose tissue-derived stem cells isolated by Ficoll gradient centrifugation and red blood cell lysis treatment.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(6):1224-30.
2011: Elke Decrock; Katharina D'Herde; Dmitri V Krysko; Mélissa Bol; Geert Bultynck; Vera Rogiers; Peter Vandenabeele; Mathieu Vinken; Luc Leybaert
Calcium and connexin-based intercellular communication, a deadly catch?
Cell calcium 2011;50(3):310-21.
2011: Jennifer Bolleyn; Joanna Fraczek; Stan Gaj; Daneida Lizarraga; Vera Rogiers; Joost H M van Delft; Mathieu Vinken; Tamara Vanhaecke
Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(6):1173-82.
2011: Joery De Kock; Simke Demeester; Anja Heymans; Eva Ramboer; Sarah Snykers; Tamara Vanhaecke; Steven Branson; Vera Rogiers
Evaluation of the multipotent character of human foreskin-derived precursor cells.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(6):1191-202.
2011: Joery De Kock; Liesbeth Ceelen; Ward De Spiegelaere; Christophe Casteleyn; Paul Claes; Tamara Vanhaecke; Vera Rogiers
Simple and quick method for whole-liver decellularization: a novel in vitro three-dimensional bioengineering tool?
Archives of toxicology 2011;85(6):607-12.
2011: Liesbeth Ceelen; Ward De Spiegelaere; Michael David; Jurgen De Craene; Mathieu Vinken; Tamara Vanhaecke; Vera Rogiers
Critical selection of reliable reference genes for gene expression study in the HepaRG cell line.
Biochemical pharmacology 2011;81(10):1255-61.
2011: Vera Rogiers
Is the replacement strategy, as it exists today in the EU for cosmetics, the way forward ?
Archives of toxicology 2011;85(5):363-4.
2011: Tamara Vanhaecke; Marleen Pauwels; Mathieu Vinken; Liesbeth Ceelen; Vera Rogiers
Towards an integrated in vitro strategy for repeated dose toxicity testing.
Archives of toxicology 2011;85(5):365-6.
2011: Tom Henkens; Sarah Snykers; Mathieu Vinken; Joanna Fraczek; Aneta Lukaszuk; Dirk Tourwé; Geert Verheyen; Jacky Van Gompel; Philippe Vanparys; Vera Rogiers; Tamara Vanhaecke
Preservation of hepatocellular functionality in cultures of primary rat hepatocytes upon exposure to 4-Me2N-BAVAH, a hydroxamate-based HDAC-inhibitor.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(1):100-9.
2011: Sarah Snykers; Joery De Kock; Vanhaecke Tamara; Vera Rogiers
Hepatic differentiation of mesenchymal stem cells: in vitro strategies.
Methods in molecular biology (Clifton, N.J.) 2011;698():305-14.
2011: Mathieu Vinken; Elke Decrock; Elke De Vuyst; Raf Ponsaerts; Catheleyne D'hondt; Geert Bultynck; Liesbeth Ceelen; Tamara Vanhaecke; Luc Leybaert; Vera Rogiers
Connexins: sensors and regulators of cell cycling.
Biochimica et biophysica acta 2011;1815(1):13-25.
2010: Mathieu Vinken; Tamara Vanhaecke; Liesbeth Ceelen; Vera Rogiers
Inhibition of gap junctional intercellular communication by toxic metals.
Chemical research in toxicology 2010;23(12):1862-7.
2010: Caroline De Vocht; An Ranquin; Jo A Van Ginderachter; Tamara Vanhaecke; Vera Rogiers; Patrick Van Gelder; Wim Versées; Jan Steyaert
Polymeric nanoreactors for enzyme replacement therapy of MNGIE.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e19-20.
2010: Mathieu Vinken; Tamara Vanhaecke; Vera Rogiers
Emerging roles of connexin hemichannels in gastrointestinal and liver pathophysiology.
World journal of gastrointestinal pathophysiology 2010;1(4):115-7.
2010: Stephan J A C Peters; Tamara Vanhaecke; Peggy Papeleu; Vera Rogiers; Henk P Haagsman; Klaske Van Norren
Co-culture of primary rat hepatocytes with rat liver epithelial cells enhances interleukin-6-induced acute-phase protein response.
Cell and tissue research 2010;340(3):451-7.
2010: M Pauwels; Vera Rogiers
Human health safety evaluation of cosmetics in the EU: a legally imposed challenge to science.
Toxicology and applied pharmacology 2010;243(2):260-74.
2010: Mathieu Vinken; Elke Decrock; Elke De Vuyst; Marijke De Bock; Roosmarijn E Vandenbroucke; Bruno G De Geest; Jo Demeester; Niek N Sanders; Tamara Vanhaecke; Luc Leybaert; Vera Rogiers
Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death.
Cellular and molecular life sciences : CMLS 2010;67(6):907-18.
2010: Mathieu Vinken; Sarah Snykers; Joanna Fraczek; Elke Decrock; Luc Leybaert; Vera Rogiers; Tamara Vanhaecke
DNA methyltransferase 3a expression decreases during apoptosis in primary cultures of hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(2):445-51.
2010: Inge Mannaerts; Nele R Nuytten; Vera Rogiers; Karin Vanderkerken; Leo van Grunsven; Albert Geerts
Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo.
Hepatology (Baltimore, Md.) 2010;51(2):603-14.
2009: Tamara Vanhaecke; Sarah Snykers; Vera Rogiers; B Garthoff; J V Castell; J G Hengstler
EU research activities in alternative testing strategies: current status and future perspectives.
Archives of toxicology 2009;83(12):1037-42.
2009: Joery De Kock; Tamara Vanhaecke; Jeffrey Biernaskie; Vera Rogiers; Sarah Snykers
Characterization and hepatic differentiation of skin-derived precursors from adult foreskin by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(8):1522-7.
2009: Elke De Vuyst; Nan Wang; Elke Decrock; Marijke De Bock; Mathieu Vinken; Marijke Van Moorhem; Charles Lai; Maxime Culot; Vera Rogiers; Romeo Cecchelli; Christian C Naus; W Howard Evans; Luc Leybaert
Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells.
Cell calcium 2009;46(3):176-87.
2009: Caroline De Vocht; An Ranquin; Ronnie Willaert; Jo A Van Ginderachter; Tamara Vanhaecke; Vera Rogiers; Wim Versées; Patrick Van Gelder; Jan Steyaert
Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE.
Journal of controlled release : official journal of the Controlled Release Society 2009;137(3):246-54.
2009: Joanna Fraczek; Sarah Deleu; Aneta Lukaszuk; Tatyana Doktorova; Dirk Tourwé; Albert Geerts; Tamara Vanhaecke; Karin Vanderkerken; Vera Rogiers
Screening of amide analogues of Trichostatin A in cultures of primary rat hepatocytes: search for potent and safe HDAC inhibitors.
Investigational new drugs 2009;27(4):338-46.
2009: Mathieu Vinken; Tatyana Doktorova; Elke Decrock; Luc Leybaert; Tamara Vanhaecke; Vera Rogiers
Gap junctional intercellular communication as a target for liver toxicity and carcinogenicity.
Critical reviews in biochemistry and molecular biology 2009;44(4):201-22.
2009: Sarah Snykers; Tom Henkens; Evelien De Rop; Mathieu Vinken; Joanna Fraczek; Joery De Kock; Evi De Prins; Albert Geerts; Vera Rogiers; Tamara Vanhaecke
Role of epigenetics in liver-specific gene transcription, hepatocyte differentiation and stem cell reprogrammation.
Journal of hepatology 2009;51(1):187-211.
2009: Mathieu Vinken; Elke Decrock; Elke De Vuyst; Luc Leybaert; Tamara Vanhaecke; Vera Rogiers
Biochemical characterisation of an in vitro model of hepatocellular apoptotic cell death.
Alternatives to laboratory animals : ATLA 2009;37(2):209-18.
2009: Sarah Snykers; Joery De Kock; Vera Rogiers; Tamara Vanhaecke
In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art.
Stem cells (Dayton, Ohio) 2009;27(3):577-605.
2009: Kristien De Paepe; A Wibaux; C Ward; Vera Rogiers
Skin efficacy and biophysical assessment of glycerol-containing hydrocolloid patches.
Skin pharmacology and physiology 2009;22(5):258-65.
2009: Kristien De Paepe; Evi Houben; R Adam; Jean-Pierre Hachem; Diane Roseeuw; Vera Rogiers
Seasonal effects on the nasolabial skin condition.
Skin pharmacology and physiology 2009;22(1):8-14.
2009: Mathieu Vinken; Evelien De Rop; Elke Decrock; Elke De Vuyst; Luc Leybaert; Tamara Vanhaecke; Vera Rogiers
Epigenetic regulation of gap junctional intercellular communication: more than a way to keep cells quiet?
Biochimica et biophysica acta 2009;1795(1):53-61.
2008: Evi Houben; Ralf Adam; Jean-Pierre Hachem; Diane Roseeuw; Vera Rogiers; Kristien De Paepe
Clinical scoring and biophysical evaluation of nasolabial skin barrier damage caused by rhinorrhea.
Contact dermatitis 2008;59(5):296-300.
2008: Kristien De Paepe; Evelien De Rop; Evi Houben; Ralf Adam; Vera Rogiers
Effects of lotioned disposable handkerchiefs on skin barrier recovery after tape stripping.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2008;14(4):440-7.
2008: Mathieu Vinken; Tatyana Doktorova; Heidrun Ellinger-Ziegelbauer; Hans-Jürgen Ahr; Edward Lock; Paul Carmichael; Erwin Roggen; Joost van Delft; Jos Kleinjans; José Castell; Roque Bort; Teresa Donato; Michael Ryan; Raffaella Corvi; Hector Keun; Timothy Ebbels; Toby Athersuch; Susanna-Assunta Sansone; Philippe Rocca-Serra; Rob Stierum; Paul Jennings; Walter Pfaller; Hans Gmuender; Tamara Vanhaecke; Vera Rogiers
The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays.
Mutation research 2008;659(3):202-10.
2008: Tom Henkens; Mathieu Vinken; Aneta Lukaszuk; Dirk Tourwé; Tamara Vanhaecke; Vera Rogiers
Differential effects of hydroxamate histone deacetylase inhibitors on cellular functionality and gap junctions in primary cultures of mitogen-stimulated hepatocytes.
Toxicology letters 2008;178(1):37-43.
2008: Mathieu Vinken; Tom Henkens; Evelien De Rop; Joanna Fraczek; Tamara Vanhaecke; Vera Rogiers
Biology and pathobiology of gap junctional channels in hepatocytes.
Hepatology (Baltimore, Md.) 2008;47(3):1077-88.
2008: Vera Rogiers; Marleen Pauwels
Headlines of safety assessment of cosmetics in Europe and future perspectives.
Current problems in dermatology 2008;36():166-82.
2008: Vera Rogiers; Marleen Pauwels
The use of alternative methods in the safety assessment of cosmetic ingredients.
Current problems in dermatology 2008;36():129-65.
2008: Vera Rogiers; Marleen Pauwels
The cosmetic technical information file in practice.
Current problems in dermatology 2008;36():115-28.
2008: Vera Rogiers; Marleen Pauwels
Safety assessment of cosmetic ingredients present in technical information files of finished products.
Current problems in dermatology 2008;36():94-114.
2008: Vera Rogiers; Marleen Pauwels
Critical analysis of the safety assessment of cosmetic ingredients performed at the European level.
Current problems in dermatology 2008;36():58-93.
2008: Vera Rogiers; Marleen Pauwels
Challenges related to cosmetic safety assessment in the EU.
Current problems in dermatology 2008;36():29-57.
2008: Vera Rogiers; Marleen Pauwels
Cosmetic products and their current European regulatory framework.
Current problems in dermatology 2008;36():1-28.
2008: Evi Houben; Jean-Pierre Hachem; Kristien De Paepe; Vera Rogiers
Epidermal ceramidase activity regulates epidermal desquamation via stratum corneum acidification.
Skin pharmacology and physiology 2008;21(2):111-8.
2007: Marleen Pauwels; Vera Rogiers
EU legislations affecting safety data availability of cosmetic ingredients.
Regulatory toxicology and pharmacology : RTP 2007;49(3):308-15.
2007: Marleen Pauwels; Vera Rogiers
Database search for safety information on cosmetic ingredients.
Regulatory toxicology and pharmacology : RTP 2007;49(3):208-16.
2007: Peggy Papeleu; Andy Wullaert; Greetje Elaut; Tom Henkens; Mathieu Vinken; Georges Laus; Dirk Tourwé; Rudi Beyaert; Vera Rogiers; Tamara Vanhaecke
Inhibition of NF-kappaB activation by the histone deacetylase inhibitor 4-Me2N-BAVAH induces an early G1 cell cycle arrest in primary hepatocytes.
Cell proliferation 2007;40(5):640-55.
2007: Tom Henkens; Mathieu Vinken; Tamara Vanhaecke; Vera Rogiers
Modulation of CYP1A1 and CYP2B1 expression upon cell cycle progression in cultures of primary rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(7):1253-7.
2007: Sarah Snykers; Joery De Kock; Tamara Vanhaecke; Vera Rogiers
Differentiation of neonatal rat epithelial cells from biliary origin into immature hepatic cells by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(7):1325-31.
2007: Sarah Snykers; Mathieu Vinken; Vera Rogiers; Tamara Vanhaecke
Differential role of epigenetic modulators in malignant and normal stem cells: a novel tool in preclinical in vitro toxicology and clinical therapy.
Archives of toxicology 2007;81(8):533-44.
2007: Mathieu Vinken; Tom Henkens; Sarah Snykers; Aneta Lukaszuk; Dirk Tourwé; Vera Rogiers; Tamara Vanhaecke
The novel histone deacetylase inhibitor 4-Me2N-BAVAH differentially affects cell junctions between primary hepatocytes.
Toxicology 2007;236(1-2):92-102.
2007: Greetje Elaut; Georges Laus; Eliane Alexandre; L Richert; P Bachellier; Dirk Tourwé; Vera Rogiers; Tamara Vanhaecke
A metabolic screening study of trichostatin A (TSA) and TSA-like histone deacetylase inhibitors in rat and human primary hepatocyte cultures.
The Journal of pharmacology and experimental therapeutics 2007;321(1):400-8.
2007: Greetje Elaut; Vera Rogiers; Tamara Vanhaecke
The pharmaceutical potential of histone deacetylase inhibitors.
Current pharmaceutical design 2007;13(25):2584-620.
2007: Sarah Snykers; Tamara Vanhaecke; Ann De Becker; Peggy Papeleu; Mathieu Vinken; Ivan Van Riet; Vera Rogiers
Chromatin remodeling agent trichostatin A: a key-factor in the hepatic differentiation of human mesenchymal stem cells derived of adult bone marrow.
BMC developmental biology 2007;7():24.
2007: Evi Houben; Yoshikazu Uchida; W F Nieuwenhuizen; Kristien De Paepe; T Vanhaecke; W M Holleran; Vera Rogiers
Kinetic characteristics of acidic and alkaline ceramidase in human epidermis.
Skin pharmacology and physiology 2007;20(4):187-94.
2007: Evi Houben; Kristien De Paepe; Vera Rogiers
A keratinocyte's course of life.
Skin pharmacology and physiology 2007;20(3):122-32.
2007: Tom Henkens; Peggy Papeleu; Greetje Elaut; Mathieu Vinken; Vera Rogiers; Tamara Vanhaecke
Trichostatin A, a critical factor in maintaining the functional differentiation of primary cultured rat hepatocytes.
Toxicology and applied pharmacology 2007;218(1):64-71.
2006: Sarah Snykers; Tamara Vanhaecke; Peggy Papeleu; Aernout Luttun; Yuehua Jiang; Yvan Vander Heyden; Catherine Verfaillie; Vera Rogiers
Sequential exposure to cytokines reflecting embryogenesis: the key for in vitro differentiation of adult bone marrow stem cells into functional hepatocyte-like cells.
Toxicological sciences : an official journal of the Society of Toxicology 2006;94(2):330-41; discussion 235-9.
2006: Greetje Elaut; Tom Henkens; Peggy Papeleu; Sarah Snykers; Mathieu Vinken; Tamara Vanhaecke; Vera Rogiers
Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures.
Current drug metabolism 2006;7(6):629-60.
2006: Mathieu Vinken; Tom Henkens; Tamara Vanhaecke; Peggy Papeleu; Albert Geerts; Elke Van Rossen; James K Chipman; Paolo Meda; Vera Rogiers
Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes.
Toxicological sciences : an official journal of the Society of Toxicology 2006;91(2):484-92.
2006: Evi Houben; Kristien De Paepe; Vera Rogiers
Skin condition associated with intensive use of alcoholic gels for hand disinfection: a combination of biophysical and sensorial data.
Contact dermatitis 2006;54(5):261-7.
2006: Evi Houben; Walter M Holleran; Toshiaki Yaginuma; Cungui Mao; Lina M Obeid; Vera Rogiers; Yutaka Takagi; Peter M Elias; Yoshikazu Uchida
Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis.
Journal of lipid research 2006;47(5):1063-70.
2006: Mathieu Vinken; Tamara Vanhaecke; Peggy Papeleu; Sarah Snykers; Tom Henkens; Vera Rogiers
Connexins and their channels in cell growth and cell death.
Cellular signalling 2006;18(5):592-600.
2006: Mathieu Vinken; Peggy Papeleu; Sarah Snykers; Evelien De Rop; Tom Henkens; James K Chipman; Vera Rogiers; Tamara Vanhaecke
Involvement of cell junctions in hepatocyte culture functionality.
Critical reviews in toxicology 2006;36(4):299-318.
2006: Sarah Snykers; Tamara Vanhaecke; Vera Rogiers
Isolation of rat bone marrow stem cells.
Methods in molecular biology (Clifton, N.J.) 2006;320():265-72.
2006: Greetje Elaut; Peggy Papeleu; Mathieu Vinken; Tom Henkens; Sarah Snykers; Tamara Vanhaecke; Vera Rogiers
Hepatocytes in suspension.
Methods in molecular biology (Clifton, N.J.) 2006;320():255-63.
2006: Mathieu Vinken; Greetje Elaut; Tom Henkens; Peggy Papeleu; Sarah Snykers; Tamara Vanhaecke; Vera Rogiers
Rat hepatocyte cultures: collagen gel sandwich and immobilization cultures.
Methods in molecular biology (Clifton, N.J.) 2006;320():247-54.
2006: Tom Henkens; Tamara Vanhaecke; Peggy Papeleu; Greetje Elaut; Mathieu Vinken; Sarah Snykers; Vera Rogiers
Rat hepatocyte cultures: conventional monolayer and cocultures with rat liver epithelial cells.
Methods in molecular biology (Clifton, N.J.) 2006;320():239-46.
2006: Peggy Papeleu; Tamara Vanhaecke; Tom Henkens; Greetje Elaut; Mathieu Vinken; Sarah Snykers; Vera Rogiers
Isolation of rat hepatocytes.
Methods in molecular biology (Clifton, N.J.) 2006;320():229-37.
2006: Tamara Vanhaecke; Vera Rogiers
Hepatocyte cultures in drug metabolism and toxicological research and testing.
Methods in molecular biology (Clifton, N.J.) 2006;320():209-27.
2005: André O Barel; Mario Calomme; A Timchenko; Kristien De Paepe; K De Paepe; N Demeester; Vera Rogiers; Peter Clarys; Dirk Vanden Berghe
Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin.
Archives of dermatological research 2005;297(4):147-53.
2005: Jean-Pierre Hachem; Mao-Qiang Man; Debra Crumrine; Yoshikazu Uchida; Barbara E Brown; Vera Rogiers; Diane Roseeuw; Kenneth R Feingold; Peter M Elias
Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity.
The Journal of investigative dermatology 2005;125(3):510-20.
2005: Sandra Coecke; Bas J Blaauboer; Greetje Elaut; Stuart Freeman; Andreas P Freidig; Nigel Gensmantel; Peter Hoet; Vassilios M Kapoulas; Bernhard Ladstetter; Gill Langley; David Leahy; Geert Mannens; Annarita Meneguz; Mario Monshouwer; Ben Nemery; Olavi Pelkonen; Walter Pfaller; Pilar Prieto; Nick Proctor; Vera Rogiers; Amin Rostami-Hodjegan; Enrico Sabbioni; Winfried Steiling; Johannes J M van de Sandt
Toxicokinetics and metabolism.
Alternatives to laboratory animals : ATLA 2005;33 Suppl 1():147-75.
2005: Walter Diembeck; Chantra Eskes; Jon R Heylings; Gill Langley; Vera Rogiers; Johannes J M van de Sandt; Valérie Zuang
Skin absorption and penetration.
Alternatives to laboratory animals : ATLA 2005;33 Suppl 1():105-7.
2005: Greetje Elaut; Tamara Vanhaecke; Y Vander Heyden; Vera Rogiers
Spontaneous apoptosis, necrosis, energy status, glutathione levels and biotransformation capacities of isolated rat hepatocytes in suspension: effect of the incubation medium.
Biochemical pharmacology 2005;69(12):1829-38.
2005: Peggy Papeleu; Tamara Vanhaecke; Greetje Elaut; Mathieu Vinken; Tom Henkens; Sarah Snykers; Vera Rogiers
Differential effects of histone deacetylase inhibitors in tumor and normal cells-what is the toxicological relevance?
Critical reviews in toxicology 2005;35(4):363-78.
2005: Kristien De Paepe; Evi Houben; Ralf Adam; Frank Wiesemann; Vera Rogiers
Validation of the VapoMeter, a closed unventilated chamber system to assess transepidermal water loss vs. the open chamber Tewameter.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2005;11(1):61-9.
2004: Tamara Vanhaecke; Tom Henkens; George E N Kass; Vera Rogiers
Effect of the histone deacetylase inhibitor trichostatin A on spontaneous apoptosis in various types of adult rat hepatocyte cultures.
Biochemical pharmacology 2004;68(4):753-60.
2004: Vera Rogiers
ECOPA: the European Consensus Platform on Three Rs Alternatives.
Alternatives to laboratory animals : ATLA 2004;32 Suppl 1A():349-53.
2004: Greetje Elaut; Georges Laus; Peggy Papeleu; Gabriëlla Török; Dirk Tourwé; Tamara Vanhaecke; Vera Rogiers
Rat hepatocyte suspensions as a suitable in vitro model for studying the biotransformation of histone deacetylase inhibitors.
Alternatives to laboratory animals : ATLA 2004;32 Suppl 1A():105-12.
2004: Peggy Papeleu; Tamara Vanhaecke; Greetje Elaut; Christiane Guguen-Guillouzo; Tom Henkens; Pascal Loyer; Vera Rogiers
Proliferation of epidermal growth factor-stimulated hepatocytes in a hormonally defined serum-free medium.
Alternatives to laboratory animals : ATLA 2004;32 Suppl 1A():57-64.
2004: Tamara Vanhaecke; Peggy Papeleu; Greetje Elaut; Vera Rogiers
Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view.
Current medicinal chemistry 2004;11(12):1629-43.
2004: Kristien De Paepe; Arij M Weerheim; Evi Houben; Diane Roseeuw; M Ponec; Vera Rogiers
Analysis of epidermal lipids of the healthy human skin: factors affecting the design of a control population.
Skin pharmacology and physiology 2004;17(1):23-30.
2003: Mathieu Vinken; Tamara Vanhaecke; Vera Rogiers
[The role of intercellular communication via "gap junctions" in disease].
Nederlands tijdschrift voor geneeskunde 2003;147(50):2463-6.
2003: Peggy Papeleu; Pascal Loyer; Tamara Vanhaecke; Greetje Elaut; Albert Geerts; Christiane Guguen-Guillouzo; Vera Rogiers
Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes.
Journal of hepatology 2003;39(3):374-82.
2003: K Van Ommeslaeghe; Greetje Elaut; V Brecx; Peggy Papeleu; Koen Iterbeke; P Geerlings; Dirk Tourwé; Vera Rogiers
Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition.
Bioorganic & medicinal chemistry letters 2003;13(11):1861-4.
2003: Karine Hellemans; Krista Rombouts; Erik Quartier; Andrea S Dittié; Andreas Knorr; Liliane Michalik; Vera Rogiers; Frans Schuit; Walter Wahli; Albert Geerts
PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation.
Journal of lipid research 2003;44(2):280-95.
2003: Marianne Depreter; Tracy Walker; Sonja Beken; Karen De Smet; Peggy Papeleu; Tom Tytgat; Marc Espeel; Vera Rogiers; Frank Roels
Modified peroxisomes in primary hepatocyte cultures.
Advances in experimental medicine and biology 2003;544():255-64.
2002: Vera Rogiers
ecopa: a powerful concept in the way forward for alternative methods.
Alternatives to laboratory animals : ATLA 2002;30 Suppl 2():199-202.
2002: Greetje Elaut; G Török; Mathieu Vinken; Georges Laus; Peggy Papeleu; D Tourwe; Vera Rogiers
Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(12):1320-8.
2002: Kristien De Paepe; Diane Roseeuw; Vera Rogiers
Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids.
Journal of the European Academy of Dermatology and Venereology : JEADV 2002;16(6):587-94.
2002: Jean-Pierre Hachem; Kristien De Paepe; Guy Sterckx; Leonard Kaufman; Vera Rogiers; Diane Roseeuw
Evaluation of biophysical and clinical parameters of skin barrier function among hospital workers.
Contact dermatitis 2002;46(4):220-3.
2002: Marianne Depreter; Tracy Walker; Karen De Smet; Sonja Beken; Ingrid Kerckaert; Vera Rogiers; Frank Roels
Hepatocyte polarity and the peroxisomal compartment: a comparative study.
The Histochemical journal 2002;34(3-4):139-51.
2002: Jean-Pierre Hachem; Kristien De Paepe; Els Vanpee; Leonard Kaufman; Vera Rogiers; Diane Roseeuw
The effect of two moisturisers on skin barrier damage in allergic contact dermatitis.
European journal of dermatology : EJD 2002;12(2):136-8.
2002: Kristien De Paepe; Jean-Pierre Hachem; Els Vanpee; Diane Roseeuw; Vera Rogiers
Effect of rice starch as a bath additive on the barrier function of healthy but SLS-damaged skin and skin of atopic patients.
Acta dermato-venereologica 2002;82(3):184-6.
2002: Jean-Pierre Hachem; Kristien De Paepe; E Vanpée; M Bogaerts; Leonard Kaufman; Vera Rogiers; Diane Roseeuw
Efficacy of topical corticosteroids in nickel-induced contact allergy.
Clinical and experimental dermatology 2002;27(1):47-50.
2001: Tamara Vanhaecke; Greetje Elaut; Vera Rogiers
Effect of oxygen concentration on the expression of glutathione S-transferase activity in periportal and perivenous rat hepatocyte cultures.
Toxicology in vitro : an international journal published in association with BIBRA 2001;15(4-5):387-92.
2001: Kristien De Paepe; K Janssens; Jean-Pierre Hachem; Diane Roseeuw; Vera Rogiers
Squamometry as a screening method for the evaluation of hydrating products.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2001;7(3):184-92.
2001: K De Paépe; Jean-Pierre Hachem; Els Vanpee; An Goossens; M A Germaux; JM Lachapelle; Julien Lambert; L Matthieu; Diane Roseeuw; E Suys; E Van Hecke; Vera Rogiers
Beneficial effects of a skin tolerance-tested moisturizing cream on the barrier function in experimentally-elicited irritant and allergic contact dermatitis.
Contact dermatitis 2001;44(6):337-43.
2001: Karen De Smet; Pascal Loyer; David Gilot; A Vercruysse; Vera Rogiers; Christiane Guguen-Guillouzo
Effects of epidermal growth factor on CYP inducibility by xenobiotics, DNA replication, and caspase activations in collagen I gel sandwich cultures of rat hepatocytes.
Biochemical pharmacology 2001;61(10):1293-303.
2001: Tamara Vanhaecke; André Foriers; A Geerts; Elizabeth A Shephard; A Vercruysse; Vera Rogiers
Pyruvate-induced long-term maintenance of glutathione s-transferase in rat hepatocyte cultures.
Alternatives to laboratory animals : ATLA 2001;29(3):335-46.
2001: K Slaus; Michael W H Coughtrie; Sheila Sharp; Tamara Vanhaecke; A Vercruysse; Vera Rogiers
Influence of culture system and medium enrichment on sulfotransferase and sulfatase expression in male rat hepatocyte cultures.
Biochemical pharmacology 2001;61(9):1107-17.
2001: Tamara Vanhaecke; MP Derde; A Vercruysse; Vera Rogiers
Hydroxypropyl-beta-cyclodextrin as delivery system for thyroid hormones, regulating glutathione S-transferase expression in rat hepatocyte co-cultures.
Biochemical pharmacology 2001;61(9):1073-8.
2001: Vera Rogiers
EEMCO guidance for the assessment of transepidermal water loss in cosmetic sciences.
Skin pharmacology and applied skin physiology 2001;14(2):117-28.
2001: Karen De Smet; C Cavin; A Vercruysse; Vera Rogiers
Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes.
Alternatives to laboratory animals : ATLA 2001;29(2):179-92.
2001: Tamara Vanhaecke; Kai O Lindros; T Oinonen; A Vercruysse; Vera Rogiers
Triiodothyronine downregulates the periportal expression of alpha class glutathione S-transferase in rat liver.
FEBS letters 2001;487(3):356-60.
2001: Jean-Pierre Hachem; Kristien De Paepe; E Vanpée; Leonard Kaufman; Vera Rogiers; Diane Roseeuw
Combination therapy improves the recovery of the skin barrier function: an experimental model using a contact allergy patch test combined with TEWL measurements.
Dermatology (Basel, Switzerland) 2001;202(4):314-9.
2001: Sonja Beken; Karen De Smet; Marianne Depreter; Frank Roels; A Vercruysse; Vera Rogiers
Effects of L-proline on phase I and phase II xenobiotic biotransformation capacities of rat and human hepatocytes in long-term collagen gel cultures.
Alternatives to laboratory animals : ATLA 2001;29(1):35-53.
2000: Karen De Smet; T Brüning; M Blaszkewicz; H M Bolt; A Vercruysse; Vera Rogiers
Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes.
Archives of toxicology 2000;74(10):587-92.
2000: Tamara Vanhaecke; Kai O Lindros; T Oinonen; A Vercruysse; Vera Rogiers
Effect of long-term ethanol exposure on the acinar distribution of hepatic glutathione S-transferase.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(12):1470-4.
2000: Tamara Vanhaecke; Kai O Lindros; T Oinonen; S Coecke; G DeBast; IR Phillips; Elizabeth A Shephard; A Vercruysse; Vera Rogiers
Effect of ethanol on the expression of hepatic glutathione S-transferase: an in vivo/in vitro study.
Biochemical pharmacology 2000;60(10):1491-6.
2000: Kristien De Paepe; Jean-Michel Lagarde; Y Gall; Diane Roseeuw; Vera Rogiers
Microrelief of the skin using a light transmission method.
Archives of dermatological research 2000;292(10):500-10.
2000: S Coecke; Tamara Vanhaecke; André Foriers; IR Phillips; A Vercruysse; Elizabeth A Shephard; Vera Rogiers
Hormonal regulation of glutathione S-transferase expression in co-cultured adult rat hepatocytes.
The Journal of endocrinology 2000;166(2):363-71.
2000: Kristien De Paepe; MP Derde; Diane Roseeuw; Vera Rogiers
Incorporation of ceramide 3B in dermatocosmetic emulsions: effect on the transepidermal water loss of sodium lauryl sulphate-damaged skin.
Journal of the European Academy of Dermatology and Venereology : JEADV 2000;14(4):272-9.
2000: Kristien De Paepe; MP Derde; Diane Roseeuw; Vera Rogiers
Claim substantiation and efficiency of hydrating body lotions and protective creams.
Contact dermatitis 2000;42(4):227-34.
2000: Marianne Depreter; Tom Tytgat; Sonja Beken; Marc Espeel; Karen De Smet; Vera Rogiers; Frank Roels
Effects of extracellular matrix on the expression of peroxisomes in primary rat hepatocyte cultures.
Journal of hepatology 2000;32(3):381-91.
1999: Pieter De Bleser; G Xu; Krista Rombouts; Vera Rogiers; Albert Geerts
Glutathione levels discriminate between oxidative stress and transforming growth factor-beta signaling in activated rat hepatic stellate cells.
The Journal of biological chemistry 1999;274(48):33881-7.
1999: Karen De Smet; Sonja Beken; Marianne Depreter; Frank Roels; A Vercruysse; Vera Rogiers
Effect of epidermal growth factor in collagen gel cultures of rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1999;13(4-5):579-85.
1999: Sonja Beken; K Slaus; Karen De Smet; Marianne Depreter; Frank Roels; A Vercruysse; Vera Rogiers
Effect of Extracellular Matrix Composition on the Expression of Glutathione S-transferase Isoenzymes in Organotypical Hepatocyte Cultures.
Toxicology in vitro : an international journal published in association with BIBRA 1999;13(4-5):571-7.
1999: Toshiro Niki; Krista Rombouts; Pieter De Bleser; K De Smet; Vera Rogiers; Detlef Schuppan; M Yoshida; G Gabbiani; Albert Geerts
A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture.
Hepatology (Baltimore, Md.) 1999;29(3):858-67.
1999: A Geerts; Vera Rogiers
Sho-saiko-To: the right blend of traditional Oriental medicine and liver cell biology.
Hepatology (Baltimore, Md.) 1999;29(1):282-4.
1998: S Coecke; G Debast; IR Phillips; A Vercruysse; Elizabeth A Shephard; Vera Rogiers
Hormonal regulation of microsomal flavin-containing monooxygenase activity by sex steroids and growth hormone in co-cultured adult male rat hepatocytes.
Biochemical pharmacology 1998;56(8):1047-51.
1998: S Coecke; A Callaerts; Ian R Phillips; A Vercruysse; Elizabeth A Shephard; Vera Rogiers
Effect of Thyroid Hormones onFlavin-containing Monooxygenase Activity in Co-cultured Adult Rat Hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1998;12(4):335-41.
1998: Tamara Vanhaecke; Karen De Smet; Sonja Beken; M Pauwels; A Vercruysse; Vera Rogiers
Rat hepatocyte cultures. Conventional monolayer cultures and cocultures with rat liver epithelial cells.
Methods in molecular biology (Clifton, N.J.) 1998;107():311-7.
1998: Sonja Beken; Tamara Vanhaecke; Karen De Smet; M Pauwels; A Vercruysse; Vera Rogiers
Collagen-gel cultures of rat hepatocytes: collagen-gel sandwich and immobilization cultures.
Methods in molecular biology (Clifton, N.J.) 1998;107():303-9.
1998: Karen De Smet; Sonja Beken; Tamara Vanhaecke; M Pauwels; A Vercruysse; Vera Rogiers
Isolation of rat hepatocytes.
Methods in molecular biology (Clifton, N.J.) 1998;107():295-301.
1998: Vera Rogiers; A Vercruysse
Hepatocyte cultures in drug metabolism and toxicological research and testing.
Methods in molecular biology (Clifton, N.J.) 1998;107():279-94.
1997: Sonja Beken; M Pauwels; S Pahernik; H G Koebe; A Vercruysse; Vera Rogiers
Collagen gel sandwich and immobilization cultures of rat hepatocytes: Problems encountered in expressing glutathione S-transferase activities.
Toxicology in vitro : an international journal published in association with BIBRA 1997;11(6):741-52.
1997: Karen De Smet; A Callaerts; A Vercruysse; Vera Rogiers
Effect of phenobarbital on 7-Ethoxycoumarin-O-deethylase and microsomal epoxide hydrase activities in collagen gel cultures of rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1997;11(5):459-63.
1997: Tamara Vanhaecke; A Vercruysse; Vera Rogiers
Effect of pyruvate on glutathione s-transferase expression in primary cultures of rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1997;11(5):435-41.
1997: Sonja Beken; Tom Tytgat; S Pahernik; H G Koebe; A Vercruysse; Vera Rogiers
Cell morphology, albumin secretion and glutathione S-Transferase expression in collagen gel sandwich and immobilization cultures of rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1997;11(5):409-16.
1997: Pieter De Bleser; Toshiro Niki; G Xu; Vera Rogiers; Albert Geerts
Localization and cellular sources of activins in normal and fibrotic rat liver.
Hepatology (Baltimore, Md.) 1997;26(4):905-12.
1997: G Xu; Toshiro Niki; I Virtanen; Vera Rogiers; Pieter De Bleser; Albert Geerts
Gene expression and synthesis of fibronectin isoforms in rat hepatic stellate cells. Comparison with liver parenchymal cells and skin fibroblasts.
The Journal of pathology 1997;183(1):90-8.
1997: M Cornet; Vera Rogiers
Metabolism and toxicity of 2-methylpropene (isobutene)--a review.
Critical reviews in toxicology 1997;27(3):223-32.
1997: Pieter De Bleser; Toshiro Niki; Vera Rogiers; Albert Geerts
Transforming growth factor-beta gene expression in normal and fibrotic rat liver.
Journal of hepatology 1997;26(4):886-93.
1997: Vera Rogiers; Y Vandenberghe; Tamara Vanhaecke; A Geerts; A Callaerts; J Carleer; J Roba; A Vercruysse
Observation of hepatotoxic effects of 2-n-pentylaminoacetamide (Milacemide) in rat liver by a combined in vivo/in vitro approach.
Archives of toxicology 1997;71(5):271-82.
1996: K Mertens; S Kaufman; S Waterschoot; A Vercruysse; Vera Rogiers
Effect of tertiary butylhydroperoxide-induced oxidative stress on glutathione content and thiobarbituric acid reactive substances production in cultures and co-cultures of adult rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1996;10(4):507-11.
1996: K Mertens; A Vercruysse; R Rahmani; S Kaufman; S Waterschoot; Vera Rogiers
Interspecies differences in glutathione-dependent detoxication of hydroperoxides in short-term cultures of hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1996;10(4):473-8.
1995: Vera Rogiers; B Blaauboer; P Maurel; IR Phillips; Elizabeth A Shephard
Hepatocyte-based in vitro models and their application in pharmacotoxicology Report of an EC DGXII meeting with representatives of the European pharmaceutical industry.
Toxicology in vitro : an international journal published in association with BIBRA 1995;9(5):685-94.
1995: M Cornet; A Callaerts; U Jorritsma; Hermann M Bolt; A Vercruysse; Vera Rogiers
Species-dependent differences in biotransformation pathways of 2-methylpropene (isobutene).
Chemical research in toxicology 1995;8(7):987-92.
1995: G Debast; S Coecke; M Akrawi; André Foriers; A Vercruysse; IR Phillips; Elizabeth A Shephard; Vera Rogiers
Effect of ethanol on glutathione S-transferase expression in co-cultured rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1995;9(4):467-71.
1995: Vera Rogiers; M Akrawi; A Vercruysse; Ian R Phillips; Elizabeth A Shephard
Effects of the anticonvulsant, valproate, on the expression of components of the cytochrome-P-450-mediated monooxygenase system and glutathione S-transferases.
European journal of biochemistry / FEBS 1995;231(2):337-43.
1995: Pieter De Bleser; P Jannes; Sylvia C van Buul-Offers; Cok M Hoogerbrugge; Chris Van Schravendijk; Toshiro Niki; Vera Rogiers; J L van den Brande; Eddie Wisse; Albert Geerts
Insulinlike growth factor-II/mannose 6-phosphate receptor is expressed on CCl4-exposed rat fat-storing cells and facilitates activation of latent transforming growth factor-beta in cocultures with sinusoidal endothelial cells.
Hepatology (Baltimore, Md.) 1995;21(5):1429-37.
1995: U Jorritsma; M Cornet; Paul van Hummelen; Hermann M Bolt; A Vercruysse; Micheline Kirsch-Volders; Vera Rogiers
Comparative mutagenicity of 2-methylpropene (isobutene), its epoxide 2-methyl-1,2-epoxypropane and propylene oxide in the in vitro micronucleus test using human lymphocytes.
Mutagenesis 1995;10(2):101-4.
1995: M Cornet; A Callaerts; A Vercruysse; Vera Rogiers
In vitro biotransformation of 2-methylpropene (isobutene) in rat lung tissue in comparison with liver tissue.
Archives of toxicology 1995;70(1):64-7.
1994: M Akrawi; Vera Rogiers; A Vercruysse; Ian R Phillips; Elizabeth A Shephard
Long-term preservation and induction of drug metabolizing enzymes in co-cultured rat hepatocytes.
Biochemical Society transactions 1994;22(2):124S.
1994: M Cornet; K Mertens; A Callaerts; W Sonck; A Vercruysse; Vera Rogiers
Age- and gender-related changes in the hepatic metabolism of 2-methylpropene and relationship to epoxide metabolizing enzymes.
Mechanisms of ageing and development 1994;74(1-2):103-15.
1994: M Leutbecher; M Cornet; Vera Rogiers; Hermann M Bolt; V ] Regier S [corrected to Rogiers
DNA binding study with inhaled [14C]2-methylpropene (isobutene)
Archives of toxicology 1994;68(1):71-2.
1993: Vera Rogiers; A Vercruysse
Rat hepatocyte cultures and co-cultures in biotransformation studies of xenobiotics.
Toxicology 1993;82(1-3):193-208.
1993: P Castelain; B Criado; M Cornet; R Laib; Vera Rogiers; Micheline Kirsch-Volders
Comparative mutagenicity of structurally related aliphatic epoxides in a modified Salmonella/microsome assay.
Mutagenesis 1993;8(5):387-93.
1993: Albert Geerts; Patricia Greenwel; M Cunningham; Pieter De Bleser; Vera Rogiers; Eddie Wisse; Marcos Rojkind
Identification of connective tissue gene transcripts in freshly isolated parenchymal, endothelial, Kupffer and fat-storing cells by northern hybridization analysis.
Journal of hepatology 1993;19(1):148-58.
1993: S Coecke; A Segaert; A Vercruysse; Vera Rogiers
Expression of flavin-containing monooxygenase activity in adult rat hepatocytes under various culture conditions.
Toxicology in vitro : an international journal published in association with BIBRA 1993;7(4):487-91.
1993: M Akrawi; Elizabeth A Shephard; Ian R Phillips; A Vercruysse; Vera Rogiers
Effects of phenobarbital and valproate on the expression of cytochromes P-450 in co-cultured rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1993;7(4):477-80.
1993: K Mertens; Vera Rogiers; A Vercruysse
Measurement of malondialdehyde in cultures of adult rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1993;7(4):439-41.
1993: M Akrawi; Vera Rogiers; Y Vandenberghe; C N Palmer; A Vercruysse; Elizabeth A Shephard; Ian R Phillips
Maintenance and induction in co-cultured rat hepatocytes of components of the cytochrome P450-mediated mono-oxygenase.
Biochemical pharmacology 1993;45(8):1583-91.
1993: K Mertens; Vera Rogiers; A Vercruysse
Glutathione dependent detoxication in adult rat hepatocytes under various culture conditions.
Archives of toxicology 1993;67(10):680-5.
1992: Y Vandenberghe; L Tee; Vera Rogiers; George C T Yeoh
Transcriptional- and post-transcriptional-dependent regulation of glutathione S-transferase expression in rat hepatocytes as a function of culture conditions.
FEBS letters 1992;313(2):155-9.
1992: S Coecke; K Mertens; A Segaert; A Callaerts; A Vercruysse; Vera Rogiers
Spectrophotometric measurement of flavin-containing monooxygenase activity in freshly isolated rat hepatocytes and their cultures.
Analytical biochemistry 1992;205(2):285-8.
1992: Vera Rogiers; A Callaerts; A Vercruysse; M Akrawi; Elizabeth A Shephard; I Phillips
Effects of valproate on xenobiotic biotransformation in rat liver. In vivo and in vitro experiments.
Pharmaceutisch weekblad. Scientific edition 1992;14(3A):127-31.
1992: M Cornet; P Castelain; A Vercruysse; R Laib; Micheline Kirsch-Volders; Vera Rogiers
Mutagenicity of 2-methylpropene (isobutene) and its epoxide in a modified Salmonella assay for volatile compounds.
Mutation research 1992;271(3):213-21.
1992: Vera Rogiers; M Akrawi; Y Vandenberghe; Elizabeth A Shephard; I Phillips; A Vercruysse
Co-cultures of rat hepatocytes in the study of valproate toxicity.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1992;15():156-9.
1991: Vera Rogiers; S Coecke; Y Vandenberghe; Fabrice MOREL; A Callaerts; G Verleye; C F Van Bezooijen; André Guillouzo; A Vercruysse
Effect of the aging process on the gender and phenobarbital dependent expression of glutathione S-transferase subunits in brown Norway rat liver.
Biochemical pharmacology 1991;42(3):491-8.
1991: Y Vandenberghe; L Tee; Fabrice MOREL; Vera Rogiers; André Guillouzo; George C T Yeoh
Regulation of glutathione S-transferase gene expression by phenobarbital in cultured adult rat hepatocytes.
FEBS letters 1991;284(1):103-8.
1991: K Mertens; Vera Rogiers; W Sonck; A Vercruysse
Measurement of reduced and oxidized glutathione in cultures of adult rat hepatocytes.
Journal of chromatography 1991;565(1-2):149-57.
1991: K Mertens; Vera Rogiers; W Sonck; A Vercruysse
Reduced and oxidized glutathione contents in adult rat hepatocytes under various culture conditions.
Cell biology and toxicology 1991;7(2):101-10.
1991: D Roseeuw; A De Coninck; A M Neven; Y Vandenberghe; E Kets; Gino Benjamin Verleye; Vera Rogiers
Fresh and cryopreserved cultured keratinocyte allografts for wound healing.
Toxicology in vitro : an international journal published in association with BIBRA 1991;5(5-6):579-83.
1991: György A Csanády; D Freise; B Denk; Johannes G Filser; M Cornet; Vera Rogiers; R J Laib
Investigation of species differences in isobutene (2-methylpropene) metabolism between mice and rats.
Archives of toxicology 1991;65(2):100-5.
1991: M Cornet; W Sonck; A Callaerts; György A Csanády; A Vercruysse; R J Laib; Vera Rogiers
In vitro biotransformation of 2-methylpropene (isobutene): epoxide formation in mice liver.
Archives of toxicology 1991;65(4):263-7.
1990: Vera Rogiers; Y Vandenberghe; A Callaerts; G Verleye; M Cornet; K Mertens; W Sonck; A Vercruysse
Phase I and phase II xenobiotic biotransformation in cultures and co-cultures of adult rat hepatocytes.
Biochemical pharmacology 1990;40(8):1701-6.
1990: S Coecke; Y Vandenberghe; A Callaerts; W Sonck; G Verleye; C F Van Bezooijen; A Vercruysse; Vera Rogiers
Hepatic cytosolic glutathione S-transferase activities in ageing brown Norway rats--importance of sex differences and phenobarbital treatment for studies of ageing.
Mechanisms of ageing and development 1990;55(2):189-98.
1990: Y Vandenberghe; Fabrice MOREL; S Pemble; J B Taylor; Vera Rogiers; D Ratanasavanh; A Vercruysse; B Ketterer; André Guillouzo
Changes in expression of mRNA coding for glutathione S-transferase subunits 1-2 and 7 in cultured rat hepatocytes.
Molecular pharmacology 1990;37(3):372-6.
1990: Y Vandenberghe; A Foriers; Vera Rogiers; A Vercruysse
Changes in expression and "de novo" synthesis of glutathione S-transferase subunits in cultured adult rat hepatocytes.
Biochemical pharmacology 1990;39(4):685-90.
1990: Vera Rogiers; Y Vandenberghe; A Callaerts; W Sonck; A Vercruysse
Effects of dimethylsulphoxide on phase I and II biotransformation in cultured rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1990;4(4-5):439-42.
1989: Fabrice MOREL; Y Vandenberghe; S Pemble; J B Taylor; D Ratanasavanh; Vera Rogiers; B Ketterer; André Guillouzo
Regulation of glutathione S-transferase subunits 3 and 4 in cultured rat hepatocytes.
FEBS letters 1989;258(1):99-102.
1989: Y Vandenberghe; Fabrice MOREL; A Foriers; B Ketterer; A Vercruysse; André Guillouzo; Vera Rogiers
Effect of phenobarbital on the expression of glutathione S-transferase isoenzymes in cultured rat hepatocytes.
FEBS letters 1989;251(1-2):59-64.
1988: Vera Rogiers; Y Vandenberghe; A Callaerts; W Sonck; V Maes; A Vercruysse
The inducing and inhibiting effects of sodium valproate in vivo on the biotransformation systems of xenobiotics in isolated rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1988;18(6):665-73.
1987: Vera Rogiers; G Paeme; W Sonck; A Vercruysse
Metabolism of procyclidine in isolated rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1987;17(7):849-57.
1986: Vera Rogiers; L Adriaenssens; Y Vandenberghe; E Gepts; A Callaerts; A Vercruysse
Critical evaluation of 7-ethoxycoumarin O-deethylase activity measurement in intact isolated rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1986;16(9):817-26.
1985: Vera Rogiers; Y Vandenberghe; A Vercruysse
Inhibition of gluconeogenesis by sodium valproate and its metabolites in isolated rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1985;15(8-9):759-65.