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Markus Rojewski

Research Profile

Chemicals & Drugs

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Carolin Koenig; Pamela Fischer-Posovszky; Peter Gierschik; Markus T Rojewski; Hubert Schrezenmeier; Daniel Tews; Martin Wabitsch; Barbara Moepps
Absence of CC chemokine receptors 2a and 2b from human adipose lineage cells.
Natalie Fekete; Sandrine Fleury-Cappellesso; Daniel Fürst; Mélanie Gadelorge; Anita Ignatius; Ramin Lotfi; Volker Mailänder; Caroline Maurer; philippe Bourin; Julia Dausend; Hubert Schrezenmeier; Luc Sensebé; Markus T Rojewski
Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components.
Manfred Hönig; E Jacobsen; G Lahr; Markus T Rojewski; C Schuetz; Ansgar Schulz; Klaus Schwarz; Klaus-Michael Debatin; Wilhelm Friedrich
Immunological reconstitution in a patient with ZAP-70 deficiency following transfusion of blood lymphocytes from a previously transplanted sibling without conditioning.

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All Publications

2013: Carolin Koenig; Pamela Fischer-Posovszky; Peter Gierschik; Markus T Rojewski; Hubert Schrezenmeier; Daniel Tews; Martin Wabitsch; Barbara Moepps
Absence of CC chemokine receptors 2a and 2b from human adipose lineage cells.
Molecular and cellular endocrinology 2013;369(1-2):72-85.
2012: Natalie Fekete; Sandrine Fleury-Cappellesso; Daniel Fürst; Mélanie Gadelorge; Anita Ignatius; Ramin Lotfi; Volker Mailänder; Caroline Maurer; philippe Bourin; Julia Dausend; Hubert Schrezenmeier; Luc Sensebé; Markus T Rojewski
Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components.
Cytotherapy 2012;14(5):540-54.
2012: Manfred Hönig; E Jacobsen; G Lahr; Markus T Rojewski; C Schuetz; Ansgar Schulz; Klaus Schwarz; Klaus-Michael Debatin; Wilhelm Friedrich
Immunological reconstitution in a patient with ZAP-70 deficiency following transfusion of blood lymphocytes from a previously transplanted sibling without conditioning.
Bone marrow transplantation 2012;47(2):305-7.
2012: Natalie Fekete; Daniel Fürst; Anita Ignatius; Ludwika Kreja; Markus T Rojewski; Julia Dausend; Hubert Schrezenmeier
GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC.
PloS one 2012;7(8):e43255.
2011: Ramin Lotfi; Christian Nienhaus; Markus T Rojewski; Judith Eisenbacher; Karin Fuchs; Ghasem Solgi; Tatjana Yildiz; Hubert Schrezenmeier
Human mesenchymal stem cells respond to native but not oxidized damage associated molecular pattern molecules from necrotic (tumor) material.
European journal of immunology 2011;41(7):2021-8.
2010: Jochen Greiner; Anita Schmitt; Krzysztof Giannopoulos; Markus T Rojewski; Marlies Götz; Isabel Funk; Mark Ringhoffer; Donald Bunjes; Susanne Hofmann; Gerd Ritter; Hartmut Döhner; Michael Schmitt
High-dose RHAMM-R3 peptide vaccination for patients with acute myeloid leukemia, myelodysplastic syndrome and multiple myeloma.
Haematologica 2010;95(7):1191-7.
2010: Fei Fei; Yingzhe Yu; Anita Schmitt; Markus T Rojewski; Baoan Chen; Jochen Greiner; Marlies Götz; Donald Bunjes; Michael Schmitt
Effects of nilotinib on regulatory T cells: the dose matters.
Molecular cancer 2010;9():22.
2009: Susan Lösler; Sarah Schlief; Christiane Kneifel; Eckhard Thiel; Hubert Schrezenmeier; Markus T Rojewski
Antimony-trioxide- and arsenic-trioxide-induced apoptosis in myelogenic and lymphatic cell lines, recruitment of caspases, and loss of mitochondrial membrane potential are enhanced by modulators of the cellular glutathione redox system.
Annals of hematology 2009;88(11):1047-58.
2009: Heike H Breitinger; Markus T Rojewski; Hubert Schrezenmeier
Antibodies to glycosylphosphatidyl-inositol anchored proteins (GPI-AP) in antithymocyte and antilymphocyte globulin: possible role for the expansion of GPI-AP deficient cells in aplastic anemia.
Annals of hematology 2009;88(9):889-95.
2009: Klaus Schwarz; Achille Iolascon; Fatima Verissimo; Nikolaus S Trede; Wyatt Horsley; Wen Chen; Barry H Paw; Karl-Peter Hopfner; Karlheinz Holzmann; Roberta Russo; Maria Rosaria Esposito; Daniela Spano; Luigia De Falco; Katja Heinrich; Brigitte Joggerst; Markus T Rojewski; Silverio Perrotta; Jonas Denecke; Ulrich Pannicke; Jean Delaunay; Rainer Pepperkok; Hermann Heimpel
Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II.
Nature genetics 2009;41(8):936-40.
2009: Anita Schmitt; Thomas F E Barth; Eva Beyer; Franziska Borchert; Markus T Rojewski; Jinfei Chen; Philippe Guillaume; Silke Gronau; Jochen Greiner; Peter Möller; Herbert Riechelmann; Michael Schmitt
The tumor antigens RHAMM and G250/CAIX are expressed in head and neck squamous cell carcinomas and elicit specific CD8+ T cell responses.
International journal of oncology 2009;34(3):629-39.
2009: Ulrich Pannicke; Manfred Hönig; Isabell Hess; Claudia Friesen; Karlheinz Holzmann; Eva-Maria Rump; Thomas F Barth; Markus T Rojewski; Ansgar Schulz; Thomas Boehm; Wilhelm Friedrich; Klaus Schwarz
Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2.
Nature genetics 2009;41(1):101-5.
2009: Fei Fei; Yingzhe Yu; Anita Schmitt; Markus T Rojewski; Baoan Chen; Marlies Götz; Hartmut Döhner; Donald Bunjes; Michael Schmitt
Dasatinib inhibits the proliferation and function of CD4+CD25+ regulatory T cells.
British journal of haematology 2009;144(2):195-205.
2008: Fei Fei; Yingzhe Yu; Anita Schmitt; Markus T Rojewski; Baoan Chen; Jochen Greiner; Marlies Götz; Philippe Guillaume; Hartmut Döhner; Donald Bunjes; Michael Schmitt
Dasatinib exerts an immunosuppressive effect on CD8+ T cells specific for viral and leukemia antigens.
Experimental hematology 2008;36(10):1297-308.
2008: Jinfei Chen; Anita Schmitt; B Chen; Markus T Rojewski; V Rübeler; F Fei; Y Yu; X Yu; Mark Ringhoffer; Stephanie von Harsdorf; Jochen Greiner; M Götzz; P Guillaume; H Döhner; Donald Bunjes; Michael Schmitt
Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signalling.
Journal of cellular and molecular medicine 2008;12(5B):2107-18.
2008: Michael Schmitt; Anita Schmitt; Markus T Rojewski; Jinfei Chen; Krzysztof Giannopoulos; Fei Fei; Yingzhe Yu; Marlies Götz; Marta Heyduk; Gerd Ritter; Daniel E Speiser; Sacha Gnjatic; Philippe Guillaume; Mark Ringhoffer; Richard F Schlenk; Peter Liebisch; Donald Bunjes; Hiroshi Shiku; Hartmut Dohner; Jochen Greiner
RHAMM-R3 peptide vaccination in patients with acute myeloid leukemia, myelodysplastic syndrome, and multiple myeloma elicits immunologic and clinical responses.
Blood 2008;111(3):1357-65.
2007: Jinfei Chen; Anita Schmitt; Krzysztof Giannopoulos; Baoan Chen; Markus T Rojewski; Hartmut Döhner; Donald Bunjes; Michael Schmitt
Imatinib impairs the proliferation and function of CD4+CD25+ regulatory T cells in a dose-dependent manner.
International journal of oncology 2007;31(5):1133-9.
2007: Jinfei Chen; Anita Schmitt; Baoan Chen; Markus T Rojewski; Mark Ringhoffer; Stephanie von Harsdorf; Jochen Greiner; Philippe Guillaume; Hartmut Döhner; Donald Bunjes; Michael Schmitt
Imatinib impairs CD8+ T lymphocytes specifically directed against the leukemia-associated antigen RHAMM/CD168 in vitro.
Cancer immunology, immunotherapy : CII 2007;56(6):849-61.
2007: Juliane M I Wiehe; Peter Ponsaerts; Markus T Rojewski; Joerg M Homann; Jochen Greiner; Desiree Kronawitter; Hubert Schrezenmeier; Vinzenz Hombach; Markus Wiesneth; Oliver Zimmermann; Jan Torzewski
mRNA-mediated gene delivery into human progenitor cells promotes highly efficient protein expression.
Journal of cellular and molecular medicine 2007;11(3):521-30.
2007: Manfred Hönig; Michael H Albert; Ansgar Schulz; Monika Sparber-Sauer; Catharina Schütz; Bernd H Belohradsky; Tayfun Güngör; Markus T Rojewski; Harald Bode; Ulrich Pannicke; Dominique Lippold; Klaus Schwarz; Klaus-Michael Debatin; Michael S Hershfield; Wilhelm Friedrich
Patients with adenosine deaminase deficiency surviving after hematopoietic stem cell transplantation are at high risk of CNS complications.
Blood 2007;109(8):3595-602.
2006: Markus T Rojewski; Hubert Schrezenmeier; Willy A Flegel
Tissue distribution of blood group membrane proteins beyond red cells: evidence from cDNA libraries.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2006;35(1):71-82.
2005: Fabian Beier; Stefan Balabanov; Tom Buckley; Klaus Dietz; Ulrike Hartmann; Markus T Rojewski; Lothar Kanz; Hubert Schrezenmeier; Tim H Brümmendorf
Accelerated telomere shortening in glycosylphosphatidylinositol (GPI)-negative compared with GPI-positive granulocytes from patients with paroxysmal nocturnal hemoglobinuria (PNH) detected by proaerolysin flow-FISH.
Blood 2005;106(2):531-3.
2004: Florian Nolte; Oliver Friedrich; Markus T Rojewski; Rainer H A Fink; Hubert Schrezenmeier; Sixten Körper
Depolarisation of the plasma membrane in the arsenic trioxide (As2O3)-and anti-CD95-induced apoptosis in myeloid cells.
FEBS letters 2004;578(1-2):85-9.
2004: Markus T Rojewski; Sixten Körper; Hubert Schrezenmeier
Arsenic trioxide therapy in acute promyelocytic leukemia and beyond: from bench to bedside.
Leukemia & lymphoma 2004;45(12):2387-401.
2004: Markus T Rojewski; Sixten Körper; Eckhard Thiel; Hubert Schrezenmeier
Arsenic trioxide-induced apoptosis is independent of CD95 in lymphatic cell lines.
Oncology reports 2004;11(2):509-13.
2004: Markus T Rojewski; Sixten Körper; Eckhard Thiel; Hubert Schrezenmeier
Depolarization of mitochondria and activation of caspases are common features of arsenic(III)-induced apoptosis in myelogenic and lymphatic cell lines.
Chemical research in toxicology 2004;17(1):119-28.
2004: Sixten Körper; Florian Nolte; Eckhard Thiel; Hubert Schrezenmeier; Markus T Rojewski
The role of mitochondrial targeting in arsenic trioxide-induced apoptosis in myeloid cell lines.
British journal of haematology 2004;124(2):186-9.
2003: Sixten Körper; Florian Nolte; Markus T Rojewski; Eckhard Thiel; Hubert Schrezenmeier
The K+ channel openers diazoxide and NS1619 induce depolarization of mitochondria and have differential effects on cell Ca2+ in CD34+ cell line KG-1a.
Experimental hematology 2003;31(9):815-23.
2002: Markus T Rojewski; Claudia D Baldus; Wolfgang Knauf; Eckhard Thiel; Hubert Schrezenmeier
Dual effects of arsenic trioxide (As2O3) on non-acute promyelocytic leukaemia myeloid cell lines: induction of apoptosis and inhibition of proliferation.
British journal of haematology 2002;116(3):555-63.
2000: Hubert Schrezenmeier; A Hildebrand; Markus T Rojewski; H Häcker; Hermann Heimpel; A Raghavachar
Paroxysmal nocturnal haemoglobinuria: a replacement of haematopoietic tissue?
Acta haematologica 2000;103(1):41-8.