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Maurizio Bifulco

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Simona Pisanti; Alba D'Alessandro; Chiara Laezza; Paola Picardi; Maurizio Bifulco
The endocannabinoid signaling system in cancer.
Anna Maria Malfitano; Clementina Manera; Giuseppe Matarese; Claudio Procaccini; Giuseppe Saccomanni; Tiziano Tuccinardi; Alba D'Alessandro; Patrizia Gazzerro; Chiara Laezza; Marco Macchia; Maurizio Bifulco
Effects on Immune Cells of a New 1,8-Naphthyridin-2-One Derivative and Its Analogues as Selective CB2 Agonists: Implications in Multiple Sclerosis.
Chiara Laezza; Anna Maria Malfitano; Simona Paladino; Simona Pisanti; Antonietta Santoro; Maurizio Bifulco; Maria Chiara Proto; Elena Ciaglia; Alba D'Alessandro; Patrizia Gazzerro
Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells.

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All Publications

2013: Simona Pisanti; Alba D'Alessandro; Chiara Laezza; Paola Picardi; Maurizio Bifulco
The endocannabinoid signaling system in cancer.
Trends in pharmacological sciences 2013;34(5):273-82.
2013: Anna Maria Malfitano; Clementina Manera; Giuseppe Matarese; Claudio Procaccini; Giuseppe Saccomanni; Tiziano Tuccinardi; Alba D'Alessandro; Patrizia Gazzerro; Chiara Laezza; Marco Macchia; Maurizio Bifulco
Effects on Immune Cells of a New 1,8-Naphthyridin-2-One Derivative and Its Analogues as Selective CB2 Agonists: Implications in Multiple Sclerosis.
PloS one 2013;8(5):e62511.
2012: Chiara Laezza; Anna Maria Malfitano; Simona Paladino; Simona Pisanti; Antonietta Santoro; Maurizio Bifulco; Maria Chiara Proto; Elena Ciaglia; Alba D'Alessandro; Patrizia Gazzerro
Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells.
European journal of cancer (Oxford, England : 1990) 2012;48(16):3112-22.
2012: Marcella Salzano; Maurizio Bifulco; Loredana Postiglione; Maria Rosaria Rusciano; Eleonora Russo; Mario Vitale
Calcium/calmodulin-dependent protein kinase II (CaMKII) phosphorylates Raf-1 at serine 338 and mediates Ras-stimulated Raf-1 activation.
Cell cycle (Georgetown, Tex.) 2012;11(11):2100-6.
2012: Clementina Manera; Flavio Rizzolio; Giuseppe Saccomanni; Tiziano Tuccinardi; Simone Bertini; Maurizio Bifulco; Francesca Castelli; Vincenzo Di Marzo; Antonio Giordano; Chiara Laezza; Alessia Ligresti; Valentina Lucchesi; Marco Macchia; Anna Maria Malfitano; Adriano Martinelli
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold.
European journal of medicinal chemistry 2012;52():284-94.
2012: Anna Maria Malfitano; Giuseppe Matarese; Alba D'Alessandro; Mario Galgani; Patrizia Gazzerro; Chiara Laezza; Maurizio Bifulco
The CB1 receptor antagonist rimonabant controls cell viability and ascitic tumour growth in mice.
Pharmacological research : the official journal of the Italian Pharmacological Society 2012;65(3):365-71.
2012: Maria Gabriella Caruso; Anna Maria Cisternino; Patrizia Gazzerro; Vito Guerra; Chiara Laezza; Giovanni Misciagna; Maria Notarnicola; Maurizio Bifulco
Cannabinoid type 1 receptor gene polymorphism and macronutrient intake.
Journal of nutrigenetics and nutrigenomics 2012;5(6):305-13.
2012: Maria C Proto; Antonietta Santoro; Luciano Di Croce; Patrizia Gazzerro; Chiara Laezza; Anna Maria Malfitano; Simona Pisanti; Maurizio Bifulco
Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth.
Journal of cellular physiology 2012;227(1):250-8.
2011: Lucia Prota; Antonietta Santoro; Maurizio Bifulco; Rita P Aquino; Teresa Mencherini; Paola Russo
Leucine enhances aerosol performance of naringin dry powder and its activity on cystic fibrosis airway epithelial cells.
International journal of pharmaceutics 2011;412(1-2):8-19.
2011: Simona Pisanti; Paola Picardi; Lucia Prota; Maria Chiara Proto; Chiara Laezza; Paul G McGuire; Lucia Morbidelli; Patrizia Gazzerro; Marina Ziche; Arup Das; Maurizio Bifulco
Genetic and pharmacologic inactivation of cannabinoid CB1 receptor inhibits angiogenesis.
Blood 2011;117(20):5541-50.
2011: Anna Maria Malfitano; Elena Ciaglia; Giuseppina Gangemi; Patrizia Gazzerro; Chiara Laezza; Maurizio Bifulco
Update on the endocannabinoid system as an anticancer target.
Expert opinion on therapeutic targets 2011;15(3):297-308.
2011: Anna Maria Malfitano; Silvio Sosa; Chiara Laezza; Marco De Bortoli; Aurelia Tubaro; Maurizio Bifulco
Rimonabant reduces keratinocyte viability by induction of apoptosis and exerts topical anti-inflammatory activity in mice.
British journal of pharmacology 2011;162(1):84-93.
2010: Mario Scrima; Sara Di Marino; Manuela Grimaldi; Antonia Mastrogiacomo; Ettore Novellino; Maurizio Bifulco; Anna Maria D'Ursi
Binding of the hemopressin peptide to the cannabinoid CB1 receptor: structural insights.
Biochemistry 2010;49(49):10449-57.
2010: Chiara Laezza; Anna Maria Malfitano; Tiziana di Matola; Paolo Ricchi; Maurizio Bifulco
Involvement of Akt/NF-κB pathway in N6-isopentenyladenosine-induced apoptosis in human breast cancer cells.
Molecular carcinogenesis 2010;49(10):892-901.
2010: Dario Gallotta; Patrizia Nigro; Roberta Cotugno; Patrizia Gazzerro; Maurizio Bifulco; Maria Antonietta Belisario
Rimonabant-induced apoptosis in leukemia cell lines: activation of caspase-dependent and -independent pathways.
Biochemical pharmacology 2010;80(3):370-80.
2010: Michele Linsalata; Maria Notarnicola; Valeria Tutino; Maurizio Bifulco; Antonietta Santoro; Chiara Laezza; Caterina Messa; Antonella Orlando; Maria Gabriella Caruso
Effects of anandamide on polyamine levels and cell growth in human colon cancer cells.
Anticancer research 2010;30(7):2583-9.
2010: Chiara Laezza; Anna Maria Malfitano; Maria Chiara Proto; Iolanda Esposito; Patrizia Gazzerro; Pietro Formisano; Simona Pisanti; Antonietta Santoro; Maria Gabriella Caruso; Maurizio Bifulco
Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and of Ras farnesylation mediate antitumor effects of anandamide in human breast cancer cells.
Endocrine-related cancer 2010;17(2):495-503.
2010: Palmiero Monteleone; Maurizio Bifulco; Giuseppe Maina; Alfonso Tortorella; Patrizia Gazzerro; Maria Chiara Proto; Clara Di Filippo; Francesco Monteleone; Benedetta Canestrelli; Giovanna Buonerba; Filippo Bogetto; Mario Maj
Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms in bipolar disorder and major depression.
Pharmacological research : the official journal of the Italian Pharmacological Society 2010;61(5):400-4.
2010: Rosanna Cozzolino; Gaetano Calì; Maurizio Bifulco; Paolo Laccetti
A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis.
Investigational new drugs 2010;28(2):115-23.
2010: Patrizia Gazzerro; Anna Maria Malfitano; Maria Chiara Proto; Antonietta Santoro; Simona Pisanti; Maria Gabriella Caruso; Maria Notarnicola; Caterina Messa; Chiara Laezza; Gabriella Misso; Michele Caraglia; Maurizio Bifulco
Synergistic inhibition of human colon cancer cell growth by the cannabinoid CB1 receptor antagonist rimonabant and oxaliplatin.
Oncology reports 2010;23(1):171-5.
2009: Palmiero Monteleone; Maurizio Bifulco; Clara Di Filippo; Patrizia Gazzerro; B Canestrelli; F Monteleone; M C Proto; M Di Genio; C Grimaldi; Mario Maj
Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effects.
Genes, brain, and behavior 2009;8(7):728-32.
2009: Antonietta Santoro; Simona Pisanti; Claudia Grimaldi; Angelo A Izzo; Francesca Borrelli; Maria C Proto; Anna Maria Malfitano; Patrizia Gazzerro; Chiara Laezza; Maurizio Bifulco
Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon.
International journal of cancer. Journal international du cancer 2009;125(5):996-1003.
2009: Simona Pisanti; Maurizio Bifulco
Endocannabinoid system modulation in cancer biology and therapy.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;60(2):107-16.
2009: Angelyne Benavides; Assunta Napolitano; Carla Bassarello; Virginia Carbone; Patrizia Gazzerro; Annamaria Malfitano; Paola Saggese; Maurizio Bifulco; Sonia Piacente; cosimo pizza
Oxylipins from Dracontium loretense.
Journal of natural products 2009;72(5):813-7.
2009: Chiara Laezza; Maria Gabriella Caruso; Teresa Gentile; Maria Notarnicola; Anna Maria Malfitano; Tiziana di Matola; Caterina Messa; Patrizia Gazzerro; Maurizio Bifulco
N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1.
International journal of cancer. Journal international du cancer 2009;124(6):1322-9.
2009: Simona Pisanti; Anna Maria Malfitano; Claudia Grimaldi; Antonietta Santoro; Patrizia Gazzerro; Chiara Laezza; Maurizio Bifulco
Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents.
Best practice & research. Clinical endocrinology & metabolism 2009;23(1):117-31.
2009: Maurizio Bifulco; Antonietta Santoro; Chiara Laezza; Anna Maria Malfitano
Cannabinoid receptor CB1 antagonists state of the art and challenges.
Vitamins and hormones 2009;81():159-89.
2008: Maurizio Bifulco; Magda Marasco; Simona Pisanti
Dietary recommendations in the medieval Medical School of Salerno: a lesson from the past.
American journal of preventive medicine 2008;35(6):602-3.
2008: Iolanda Esposito; Maria Chiara Proto; Patrizia Gazzerro; Chiara Laezza; Claudia Miele; Anna Teresa Alberobello; Vittoria D'Esposito; Francesco Beguinot; Pietro Formisano; Maurizio Bifulco
The cannabinoid CB1 receptor antagonist rimonabant stimulates 2-deoxyglucose uptake in skeletal muscle cells by regulating the expression of phosphatidylinositol-3-kinase.
Molecular pharmacology 2008;74(6):1678-86.
2008: Chiara Laezza; Laura Fiorentino; Simona Pisanti; Patrizia Gazzerro; Michele Caraglia; Giuseppe Portella; Mario Vitale; Maurizio Bifulco
Lovastatin induces apoptosis of k-ras-transformed thyroid cells via inhibition of ras farnesylation and by modulating redox state.
Journal of molecular medicine (Berlin, Germany) 2008;86(12):1341-51.
2008: Chiara Laezza; Simona Pisanti; Anna Maria Malfitano; Maurizio Bifulco
The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway.
Endocrine-related cancer 2008;15(4):965-74.
2008: Anna Maria Malfitano; Maria Chiara Proto; Maurizio Bifulco
Cannabinoids in the management of spasticity associated with multiple sclerosis.
Neuropsychiatric disease and treatment 2008;4(5):847-53.
2008: Antonietta Santoro; Patrizia Gazzerro; Anna Maria Malfitano; Simona Pisanti; Chiara Laezza; Maurizio Bifulco
Reply to the letter to the editor "Long-term cannabinoid receptor (CB1) blockade in obesity: implications for the development of colorectal cancer".
International journal of cancer. Journal international du cancer 2008;123(1):243-4.
2008: Maurizio Bifulco; Anna Maria Malfitano; Simona Pisanti; Chiara Laezza
Endocannabinoids in endocrine and related tumours.
Endocrine-related cancer 2008;15(2):391-408.
2008: Antonietta Santoro; Giuseppe Bianco; Patrizia Picerno; Rita Aquino; Giuseppina Autore; Stefania Marzocco; Patrizia Gazzerro; Maria Brigida Lioi; Maurizio Bifulco
Verminoside- and verbascoside-induced genotoxicity on human lymphocytes: involvement of PARP-1 and p53 proteins.
Toxicology letters 2008;178(2):71-6.
2008: Maurizio Bifulco; Anna Maria Malfitano; Giuseppe Marasco
Potential therapeutic role of statins in neurological disorders.
Expert review of neurotherapeutics 2008;8(5):827-37.
2008: Maurizio Bifulco
Therapeutic potential of statins in thyroid proliferative disease.
Nature clinical practice. Endocrinology & metabolism 2008;4(5):242-3.
2008: Anna Maria Malfitano; Chiara Laezza; Simona Pisanti; Patrizia Gazzerro; Maurizio Bifulco
Rimonabant (SR141716) exerts anti-proliferative and immunomodulatory effects in human peripheral blood mononuclear cells.
British journal of pharmacology 2008;153(5):1003-10.
2008: Maurizio Bifulco; Anna Maria Malfitano; Maria Chiara Proto; Antonietta Santoro; Maria Gabriella Caruso; Chiara Laezza
Biological and pharmacological roles of N6-isopentenyladenosine: an emerging anticancer drug.
Anti-cancer agents in medicinal chemistry 2008;8(2):200-4.
2008: Carla Esposito; Mario Scrima; Alfonso Carotenuto; Annamaria Tedeschi; Paolo Rovero; Gerardino D'Errico; Anna Maria Malfitano; Maurizio Bifulco; Anna Maria D'Ursi
Structures and micelle locations of the nonlipidated and lipidated C-terminal membrane anchor of 2',3'-cyclic nucleotide-3'-phosphodiesterase.
Biochemistry 2008;47(1):308-19.
2008: Maria Notarnicola; Caterina Messa; Antonella Orlando; Maurizio Bifulco; Chiara Laezza; Patrizia Gazzerro; Maria Gabriella Caruso
Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines.
Scandinavian journal of gastroenterology 2008;43(1):66-72.
2008: Maurizio Bifulco
In memory of Nino Salvatore: tenth anniversary.
Thyroid : official journal of the American Thyroid Association 2008;18(1):91-2.
2007: Maurizio Bifulco; Maria Gabriella Caruso
From the gastronomic revolution to the new globesity epidemic.
Journal of the American Dietetic Association 2007;107(12):2058-60.
2007: Stefania Stingo; Mariorosario Masullo; Eugenia Polverini; Chiara Laezza; Immacolata Ruggiero; Rosaria Arcone; Enrica Ruozi; Fabrizio Dal Piaz; Anna Maria Malfitano; Anna Maria D'Ursi; Maurizio Bifulco
The N-terminal domain of 2',3'-cyclic nucleotide 3'-phosphodiesterase harbors a GTP/ATP binding site.
Chemical biology & drug design 2007;70(6):502-10.
2007: Silvana Libertini; Irma Iacuzzo; Angelo Ferraro; Mario Vitale; Maurizio Bifulco; Alfredo Fusco; Giuseppe Portella
Lovastatin enhances the replication of the oncolytic adenovirus dl1520 and its antineoplastic activity against anaplastic thyroid carcinoma cells.
Endocrinology 2007;148(11):5186-94.
2007: Filippo Minutolo; Maria Grazia Cascio; I Carboni; Tiziana Bisogno; Giovanni Prota; Simone Bertini; Maria Digiacomo; Maurizio Bifulco; Vincenzo Di Marzo; Marco Macchia
Metabolically labile cannabinoid esters: a 'soft drug' approach for the development of cannabinoid-based therapeutic drugs.
Bioorganic & medicinal chemistry letters 2007;17(17):4878-81.
2007: Maurizio Bifulco; Claudia Grimaldi; Patrizia Gazzerro; Simona Pisanti; Antonietta Santoro
Rimonabant: just an antiobesity drug? Current evidence on its pleiotropic effects.
Molecular pharmacology 2007;71(6):1445-56.
2007: Patrizia Gazzerro; Maria Gabriella Caruso; Maria Notarnicola; Giovanni Misciagna; V Guerra; Chiara Laezza; Maurizio Bifulco
Association between cannabinoid type-1 receptor polymorphism and body mass index in a southern Italian population.
International journal of obesity (2005) 2007;31(6):908-12.
2007: Simona Pisanti; Cristina Borselli; Olimpia Oliviero; Chiara Laezza; Patrizia Gazzerro; Maurizio Bifulco
Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy.
Journal of cellular physiology 2007;211(2):495-503.
2007: Anna Maria Malfitano; gokce toruner; Patrizia Gazzerro; Chiara Laezza; Seema Husain; davide laptop; Pierangelo Orlando; Luciano De Petrocellis; Alexandra Terskiy; Marvin N Schwalb; Emilia Vitale; Maurizio Bifulco
Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells.
Immunology letters 2007;109(2):145-54.
2007: Maurizio Bifulco; Chiara Laezza; Patrizia Gazzerro; Francesca Pentimalli
Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion (review).
Oncology reports 2007;17(4):813-6.
2007: Maurizio Bifulco; Chiara Laezza; Anna Maria Malfitano
From anecdotal evidence of cannabinoids in multiple sclerosis to emerging new therapeutical approaches.
Multiple sclerosis (Houndmills, Basingstoke, England) 2007;13(1):133-4.
2007: Maurizio Bifulco; Paolo Cavallo
Thyroidology in the medieval Medical School of Salerno.
Thyroid : official journal of the American Thyroid Association 2007;17(1):39-40.
2006: Chiara Laezza; Simona Pisanti; Elvira Crescenzi; Maurizio Bifulco
Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cells.
FEBS letters 2006;580(26):6076-82.
2006: Chiara Laezza; Gherardo Mazziotti; Laura Fiorentino; Patrizia Gazzerro; Giuseppe Portella; Diego Gerbasio; Carlo Carella; Giuseppe Matarese; Maurizio Bifulco
HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway.
Journal of molecular medicine (Berlin, Germany) 2006;84(11):967-73.
2006: Daniela Sarnataro; Simona Pisanti; Antonietta Santoro; Patrizia Gazzerro; Anna Maria Malfitano; Chiara Laezza; Maurizio Bifulco
The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits human breast cancer cell proliferation through a lipid raft-mediated mechanism.
Molecular pharmacology 2006;70(4):1298-306.
2006: Alessia Ligresti; Aniello Schiano Moriello; Katarzyna Starowicz; Isabel Matias; Simona Pisanti; Luciano De Petrocellis; Chiara Laezza; Giuseppe Portella; Maurizio Bifulco; Vincenzo Di Marzo
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.
The Journal of pharmacology and experimental therapeutics 2006;318(3):1375-87.
2006: Maurizio Bifulco; Chiara Laezza; Simona Pisanti; Patrizia Gazzerro
Cannabinoids and cancer: pros and cons of an antitumour strategy.
British journal of pharmacology 2006;148(2):123-35.
2006: Chiara Laezza; Maria Notarnicola; Maria Gabriella Caruso; Caterina Messa; Marco Macchia; Simone Bertini; Filippo Minutolo; Giuseppe Portella; Laura Fiorentino; Stefania Stingo; Maurizio Bifulco
N6-isopentenyladenosine arrests tumor cell proliferation by inhibiting farnesyl diphosphate synthase and protein prenylation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(3):412-8.
2006: Claudia Grimaldi; Simona Pisanti; Chiara Laezza; Anna Maria Malfitano; Antonietta Santoro; Mario Vitale; Maria Gabriella Caruso; Maria Notarnicola; Irma Iacuzzo; Giuseppe Portella; Vincenzo Di Marzo; Maurizio Bifulco
Anandamide inhibits adhesion and migration of breast cancer cells.
Experimental cell research 2006;312(4):363-73.
2006: Anna Maria Malfitano; Rachel Cahill; Peter Mitchell; Gad Frankel; Gordon Dougan; Maurizio Bifulco; Giovanna Lombardi; Robert I Lechler; Kathleen B Bamford
Helicobacter pylori has stimulatory effects on naive T cells.
Helicobacter 2006;11(1):21-30.
2006: Anna Maria Malfitano; Giuseppe Matarese; Simona Pisanti; Claudia Grimaldi; Chiara Laezza; Tiziana Bisogno; Vincenzo Di Marzo; Robert I Lechler; Maurizio Bifulco
Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis.
Journal of neuroimmunology 2006;171(1-2):110-9.
2006: Maria Notarnicola; Donato F Altomare; Menotti Calvani; Antonella Orlando; Maurizio Bifulco; Benedetta D'Attoma; Maria Gabriella Caruso
Fatty acid synthase hyperactivation in human colorectal cancer: relationship with tumor side and sex.
Oncology 2006;71(5-6):327-32.
2005: Anna Maria Malfitano; Giuseppe Matarese; Maurizio Bifulco
From cannabis to endocannabinoids in multiple sclerosis: a paradigm of central nervous system autoimmune diseases.
Current drug targets. CNS and neurological disorders 2005;4(6):667-75.
2005: Caterina Messa; Maria Notarnicola; Francesco Russo; Aldo Cavallini; Valentina Pallottini; Anna Trentalance; Maurizio Bifulco; Chiara Laezza; Maria Gabriella Caruso
Estrogenic regulation of cholesterol biosynthesis and cell growth in DLD-1 human colon cancer cells.
Scandinavian journal of gastroenterology 2005;40(12):1454-61.
2005: Daniela Sarnataro; Claudia Grimaldi; Simona Pisanti; Patrizia Gazzerro; Chiara Laezza; Chiara Zurzolo; Maurizio Bifulco
Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells.
FEBS letters 2005;579(28):6343-9.
2005: Maurizio Bifulco
Role of the isoprenoid pathway in ras transforming activity, cytoskeleton organization, cell proliferation and apoptosis.
Life sciences 2005;77(14):1740-9.
2005: davide laptop; Arturo Leone; Maurizio Bifulco; Mario F Tecce
Effect of unsaturated fat intake from Mediterranean diet on rat liver mRNA expression profile: selective modulation of genes involved in lipid metabolism.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2005;15(1):13-23.
2004: Maurizio Bifulco; Chiara Laezza; Marta Valenti; Alessia Ligresti; Giuseppe Portella; Vincenzo Di Marzo
A new strategy to block tumor growth by inhibiting endocannabinoid inactivation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(13):1606-8.
2004: Gabriella Corea; Maria Iorizzi; Virginia Lanzotti; Maria Cammareri; Clara Conicella; Chiara Laezza; Maurizio Bifulco
Astersedifolioside A-C, three new oleane-type saponins with antiproliferative activity.
Bioorganic & medicinal chemistry 2004;12(18):4909-15.
2004: Eva de Lago; Alessia Ligresti; Giorgio Ortar; Enrico Morera; Ana Cabranes; Gareth Pryce; Maurizio Bifulco; David Baker; Javier Fernandez-Ruiz; Vincenzo Di Marzo
In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake.
European journal of pharmacology 2004;484(2-3):249-57.
2004: Maria Notarnicola; Caterina Messa; Aldo Cavallini; Maurizio Bifulco; Mario Felice Tecce; davide laptop; Alfredo Di Leo; Severino Montemurro; Chiara Laezza; Maria Gabriella Caruso
Higher farnesyl diphosphate synthase activity in human colorectal cancer inhibition of cellular apoptosis.
Oncology 2004;67(5-6):351-8.
2003: Giuseppe Portella; Chiara Laezza; Paolo Laccetti; Luciano De Petrocellis; Vincenzo Di Marzo; Maurizio Bifulco
Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1771-3.
2003: Alessia Ligresti; Tiziana Bisogno; Isabel Matias; Luciano De Petrocellis; Maria Grazia Cascio; Vittorio Cosenza; Giuseppe d'Argenio; Giuseppe Scaglione; Maurizio Bifulco; Italo Sorrentini; Vincenzo Di Marzo
Possible endocannabinoid control of colorectal cancer growth.
Gastroenterology 2003;125(3):677-87.
2003: Selena Harrison; Luciano De Petrocellis; Marcello Trevisani; Francesca Benvenuti; Maurizio Bifulco; Pierangelo Geppetti; Vincenzo Di Marzo
Capsaicin-like effects of N-arachidonoyl-dopamine in the isolated guinea pig bronchi and urinary bladder.
European journal of pharmacology 2003;475(1-3):107-14.
2003: Maurizio Bifulco; Vincenzo Di Marzo
[The endocannabinoid system as a target for the development of new drugs for cancer therapy].
Recenti progressi in medicina 2003;94(5):194-8.
2003: Maria Gabriella Caruso; Maria Notarnicola; Maurizio Bifulco; Chiara Laezza; Vito Guerra; Donato F Altomare; vincenzo memeo; Dionigi Lorusso; Ignazio Demma; Alfredo Di Leo
Increased farnesyltransferase activity in human colorectal cancer: relationship with clinicopathological features and K-ras mutation.
Scandinavian journal of gastroenterology 2003;38(1):80-5.
2002: Luciano De Petrocellis; Tiziana Bisogno; Alessia Ligresti; Maurizio Bifulco; Dominique Melck; Vincenzo Di Marzo
Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems.
Fundamental & clinical pharmacology 2002;16(4):297-302.
2002: Paolo Mondola; Rosalba Serù; Mariarosaria Santillo; Simona Damiano; Maurizio Bifulco; Chiara Laezza; Pietro Formisano; Giuseppe Rotilio; Maria Rosa Ciriolo
Effect of Cu,Zn superoxide dismutase on cholesterol metabolism in human hepatocarcinoma (HepG2) cells.
Biochemical and biophysical research communications 2002;295(3):603-9.
2002: Maurizio Bifulco; Vincenzo Di Marzo
Targeting the endocannabinoid system in cancer therapy: a call for further research.
Nature medicine 2002;8(6):547-50.
2002: Jason W Brooks; Gareth Pryce; Tiziana Bisogno; Siân I Jaggar; Deborah J R Hankey; Peter Brown; Daniel Bridges; Catherine Ledent; Maurizio Bifulco; Andrew S C Rice; Vincenzo Di Marzo; David Baker
Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors.
European journal of pharmacology 2002;439(1-3):83-92.
2002: Giovanni Cuda; Roberto Paternò; Roberto Ceravolo; Mafalda Candigliota; Nicola Perrotti; Francesco Perticone; Maria Concetta Faniello; Filippo Schepis; Antonio Ruocco; Evelina Mele; Susanna Cassano; Maurizio Bifulco; Mariarosaria Santillo; enrico vittorio avvedimento
Protection of human endothelial cells from oxidative stress: role of Ras-ERK1/2 signaling.
Circulation 2002;105(8):968-74.
2002: Maurizio Bifulco; Chiara Laezza; Stefania Stingo; J Wolff
2',3'-Cyclic nucleotide 3'-phosphodiesterase: a membrane-bound, microtubule-associated protein and membrane anchor for tubulin.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):1807-12.
2001: Maurizio Bifulco; Chiara Laezza; Giuseppe Portella; M Vitale; Pierangelo Orlando; Luciano De Petrocellis; Vincenzo Di Marzo
Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2745-7.
2001: Tiziana di Matola; F D'Ascoli; Cristina Luongo; Maurizio Bifulco; Guido Rossi; Gianfranco Fenzi; Mario Vitale
Lovastatin-induced apoptosis in thyroid cells: involvement of cytochrome c and lamin B.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(5):645-50.
2001: Vincenzo Di Marzo; Dominique Melck; Pierangelo Orlando; Tiziana Bisogno; O Zagoory; Maurizio Bifulco; zvi vogel; Luciano De Petrocellis
Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells.
The Biochemical journal 2001;358(Pt 1):249-55.
2000: Vincenzo Di Marzo; Maurizio Bifulco; Luciano De Petrocellis
Endocannabinoids and multiple sclerosis: a blessing from the 'inner bliss'?
Trends in pharmacological sciences 2000;21(6):195-7.
2000: Tiziana di Matola; F Mueller; Gianfranco Fenzi; Guido Rossi; Maurizio Bifulco; Luigi Marzano; Mario Vitale
Serum withdrawal-induced apoptosis in thyroid cells is caused by loss of fibronectin-integrin interaction.
The Journal of clinical endocrinology and metabolism 2000;85(3):1188-93.
2000: Paolo Mondola; Maurizio Bifulco; Rosalba Serù; T Annella; Maria Rosa Ciriolo; Mariarosaria Santillo
Presence of CuZn superoxide dismutase in human serum lipoproteins.
FEBS letters 2000;467(1):57-60.
2000: Dominique Melck; Luciano De Petrocellis; Pierangelo Orlando; Tiziana Bisogno; Chiara Laezza; Maurizio Bifulco; Vincenzo Di Marzo
Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation.
Endocrinology 2000;141(1):118-26.
1999: Mariarosaria Santillo; A Migliaro; Paolo Mondola; Chiara Laezza; Simona Damiano; Stefania Stingo; Laura Fiorentino; A Andreozzi; M Vitale; Maurizio Bifulco
Dietary and hypothyroid hypercholesterolemia induces hepatic apolipoprotein E expression in the rat: direct role of cholesterol.
FEBS letters 1999;463(1-2):83-6.
1999: Mario Vitale; Tiziana di Matola; Maurizio Bifulco; Adele Casamassima; Gianfranco Fenzi; Guido Rossi
Apoptosis induced by denied adhesion to extracellular matrix (anoikis) in thyroid epithelial cells is p53 dependent but fails to correlate with modulation of p53 expression.
FEBS letters 1999;462(1-2):57-60.
1999: Dominique Melck; Tiziana Bisogno; Luciano De Petrocellis; H Chuang; David Julius; Maurizio Bifulco; Vincenzo Di Marzo
Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors.
Biochemical and biophysical research communications 1999;262(1):275-84.
1999: Maurizio Bifulco; Chiara Laezza; S M Aloj
Inhibition of farnesylation blocks growth but not differentiation in FRTL-5 thyroid cells.
Biochimie 1999;81(4):287-90.
1999: Mayra Paolillo; Antonio Feliciello; Antonio Porcellini; Corrado Garbi; Maurizio Bifulco; Sergio Schinelli; C Ventra; Eugenio Stabile; G Ricciardelli; G Schettini; enrico vittorio avvedimento
The type and the localization of cAMP-dependent protein kinase regulate transmission of cAMP signals to the nucleus in cortical and cerebellar granule cells.
The Journal of biological chemistry 1999;274(10):6546-52.
1999: Mario Vitale; Tiziana di Matola; Guido Rossi; Chiara Laezza; Gianfranco Fenzi; Maurizio Bifulco
Prenyltransferase inhibitors induce apoptosis in proliferating thyroid cells through a p53-independent CrmA-sensitive, and caspase-3-like protease-dependent mechanism.
Endocrinology 1999;140(2):698-704.
1998: Chiara Laezza; V Di Marzo; Maurizio Bifulco
v-K-ras leads to preferential farnesylation of p21(ras) in FRTL-5 cells: multiple interference with the isoprenoid pathway.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13646-51.
1998: Chiara Laezza; Cecilia Bucci; Mariarosaria Santillo; Carmelo B Bruni; Maurizio Bifulco
Control of Rab5 and Rab7 expression by the isoprenoid pathway.
Biochemical and biophysical research communications 1998;248(3):469-72.
1998: L De Petrocellis; Dominique Melck; A Palmisano; T Bisogno; Chiara Laezza; Maurizio Bifulco; V Di Marzo
The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(14):8375-80.
1998: Cecilia Bucci; Rosalba Serù; T Annella; R Vitelli; D Lattero; Maurizio Bifulco; Paolo Mondola; Mariarosaria Santillo
Free fatty acids modulate LDL receptor activity in BHK-21 cells.
Atherosclerosis 1998;137(2):329-40.
1997: Chiara Laezza; J Wolff; Maurizio Bifulco
Identification of a 48-kDa prenylated protein that associates with microtubules as 2',3'-cyclic nucleotide 3'-phosphodiesterase in FRTL-5 cells.
FEBS letters 1997;413(2):260-4.
1997: Chiara Laezza; A Migliaro; R Cerbone; Idolo Tedesco; Mariarosaria Santillo; Corrado Garbi; Maurizio Bifulco
N6-isopentenyladenosine affects cAMP-dependent microfilament organization in FRTL-5 thyroid cells.
Experimental cell research 1997;234(1):178-82.
1997: R Vitelli; Mariarosaria Santillo; D Lattero; Mario Chiariello; Maurizio Bifulco; Carmelo B Bruni; Cecilia Bucci
Role of the small GTPase Rab7 in the late endocytic pathway.
The Journal of biological chemistry 1997;272(7):4391-7.
1996: Mariarosaria Santillo; Paolo Mondola; A Gioielli; Rosalba Serù; S Iossa; T Annella; M Vitale; Maurizio Bifulco
Inhibitors of Ras farnesylation revert the increased resistance to oxidative stress in K-Ras transformed NIH 3T3 cells.
Biochemical and biophysical research communications 1996;229(3):739-45.
1996: I M Bonapace; Raffaele Addeo; Lucia Altucci; Luigi Cicatiello; Maurizio Bifulco; Chiara Laezza; S Salzano; V Sica; Francesco Bresciani; Alessandro Weisz
17 beta-Estradiol overcomes a G1 block induced by HMG-CoA reductase inhibitors and fosters cell cycle progression without inducing ERK-1 and -2 MAP kinases activation.
Oncogene 1996;12(4):753-63.
1996: Mariarosaria Santillo; Paolo Mondola; A Milone; A Gioielli; Maurizio Bifulco
Ascorbate administration to normal and cholesterol-fed rats inhibits in vitro TBARS formation in serum and liver homogenates.
Life sciences 1996;58(14):1101-8.
1995: B Perillo; I Tedesco; Chiara Laezza; Mariarosaria Santillo; A Romano; S M Aloj; Maurizio Bifulco
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. II. Down-regulation by v-K-ras oncogene.
The Journal of biological chemistry 1995;270(25):15237-41.
1995: Maurizio Bifulco; B Perillo; M Saji; Chiara Laezza; I Tedesco; L D Kohn; S M Aloj
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. I. Identification and characterization of a cyclic AMP-responsive element in the rat reductase promoter.
The Journal of biological chemistry 1995;270(25):15231-6.
1993: Maurizio Bifulco; Chiara Laezza; S M Aloj; Corrado Garbi
Mevalonate controls cytoskeleton organization and cell morphology in thyroid epithelial cells.
Journal of cellular physiology 1993;155(2):340-8.
1992: Paolo Mondola; Mariarosaria Santillo; F Santangelo; A Belfiore; P Gambardella; Maurizio Bifulco
Effects of a new calf thymus protein on 3-hydroxy-3-methylglutaryl-CoA reductase activity in rat (Rattus bubalus) hepatocyte cells (BRL-3A).
Comparative biochemistry and physiology. B, Comparative biochemistry 1992;103(2):431-4.
1992: Mariarosaria Santillo; Paolo Mondola; F Santangelo; A Belfiore; I Tedesco; Chiara Laezza; R Cerbone; A Romano; Maurizio Bifulco
Characterization of the low density lipoprotein receptor activity in buffalo rat liver (BRL-3A) cells.
Comparative biochemistry and physiology. B, Comparative biochemistry 1992;101(3):489-94.
1991: A Milone; Mario Delfino; A Piccirillo; Gennaro Illiano; S M Aloj; Maurizio Bifulco
Increased levels of DHEAS in serum of patients with X-linked ichthyosis.
Journal of inherited metabolic disease 1991;14(1):96-104.
1990: Domenico Grieco; Z H Beg; A Romano; Maurizio Bifulco; S M Aloj
Cell cycle progression and 3-hydroxy-3-methylglutaryl coenzyme A reductase are regulated by thyrotropin in FRTL-5 rat thyroid cells.
The Journal of biological chemistry 1990;265(31):19343-50.
1990: Maurizio Bifulco; Mariarosaria Santillo; I Tedesco; Raffaele Zarrilli; Chiara Laezza; S M Aloj
Thyrotropin modulates low density lipoprotein binding activity in FRTL-5 thyroid cells.
The Journal of biological chemistry 1990;265(31):19336-42.
1989: Paolo Mondola; Mariarosaria Santillo; I Tedesco; F Santangelo; A Belfiore; Maurizio Bifulco
Thymus fraction (FIII) effect on cholesterol metabolism: modulation of the low density lipoprotein receptor pathway.
The International journal of biochemistry 1989;21(6):627-30.
1989: Paolo Mondola; Mariarosaria Santillo; F Santangelo; C Caporale; A Belfiore; Maurizio Bifulco
Purification and characterization of a calf thymus protein active on lipid metabolism.
The International journal of biochemistry 1989;21(9):1009-14.
1988: Corrado Garbi; Chiara Zurzolo; Maurizio Bifulco; Lucio Nitsch
Synthesis of extracellular matrix glycoproteins by a differentiated thyroid epithelial cell line.
Journal of cellular physiology 1988;135(1):39-46.
1988: S M Aloj; Francesco Beguinot; Maurizio Bifulco; L D Kohn
Thyrotropin regulation of thyroid cell functions: mechanisms and relationship to thyroid disease.
Annali dell'Istituto superiore di sanità 1988;24(1):117-27.
1987: Maurizio Bifulco; I Spitz; H J Hirsch; J Shorer; S M Aloj
High-molecular-weight serum thyrotropin revisited.
The New England journal of medicine 1987;316(25):1609-10.
1987: Francesco Beguinot; L Beguinot; Donatella Tramontano; C Duilio; S Formisano; Maurizio Bifulco; F S Ambesi-Impiombato; S M Aloj
Thyrotropin regulation of membrane lipid fluidity in the FRTL-5 thyroid cell line. Its relationship to cell growth and functional activity.
The Journal of biological chemistry 1987;262(4):1575-82.
1985: Maurizio Bifulco; H A Saroff; L D Kohn; S M Aloj
Thyrotropin interaction with high-density lipoproteins.
Biochimica et biophysica acta 1985;835(2):191-200.