Giovanni Biggio

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Sanna Enrico; Mostallino Maria Cristina; Murru Luca; Carta Mario; Talani Giuseppe; Zucca Stefano; Mura Maria Luisa; Maciocco Elisabetta; Biggio Giovanni
Changes in expression and function of extrasynaptic GABAA receptors in the rat hippocampus during pregnancy and after delivery.
Biggio Giovanni; Cristina Mostallino Maria; Follesa Paolo; Concas Alessandra; Sanna Enrico
GABA(A) receptor function and gene expression during pregnancy and postpartum.
Tuveri Antonella; Paoletti Anna Maria; Orrù Marisa; Melis Gian Benedetto B; Marotto Maria Francesca; Zedda Pierina; Marrosu Francesco; Sogliano Cristiana; Marra Carla; Biggio Giovanni; Concas Alessandra
Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Giovanni Biggio (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Sanna Enrico; Mostallino Maria Cristina; Murru Luca; Carta Mario; Talani Giuseppe; Zucca Stefano; Mura Maria Luisa; Maciocco Elisabetta; Biggio Giovanni
Changes in expression and function of extrasynaptic GABAA receptors in the rat hippocampus during pregnancy and after delivery.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(6):1755-65.
2009: Biggio Giovanni; Cristina Mostallino Maria; Follesa Paolo; Concas Alessandra; Sanna Enrico
GABA(A) receptor function and gene expression during pregnancy and postpartum.
International review of neurobiology 2009;85():73-94.
2008: Tuveri Antonella; Paoletti Anna Maria; Orrù Marisa; Melis Gian Benedetto B; Marotto Maria Francesca; Zedda Pierina; Marrosu Francesco; Sogliano Cristiana; Marra Carla; Biggio Giovanni; Concas Alessandra
Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy.
Epilepsia 2008;49(7):1221-9.
2008: Carta M; Murru L; Barabino E; Talani G; Sanna E; Biggio G
Isoniazid-induced reduction in GABAergic neurotransmission alters the function of the cerebellar cortical circuit.
Neuroscience 2008;154(2):710-9.
2008: Sekimata Katsuhiko; Hatano Kentaro; Ogawa Mikako; Abe Junichiro; Magata Yasuhiro; Biggio Giovanni; Serra Mariangela; Laquintana Valentino; Denora Nunzio; Latrofa Andrea; Trapani Giuseppe; Liso Gaetano; Ito Kengo
Radiosynthesis and in vivo evaluation of N-[11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors.
Nuclear medicine and biology 2008;35(3):327-34.
2008: Cappelli Andrea; Giuliani Germano; Valenti Salvatore; Anzini Maurizio; Vomero Salvatore; Giorgi Gianluca; Sogliano Cristiana; Maciocco Elisabetta; Biggio Giovanni; Concas Alessandra
Synthesis and structure-activity relationship studies in peripheral benzodiazepine receptor ligands related to alpidem.
Bioorganic & medicinal chemistry 2008;16(6):3428-37.
2008: Serra Mariangela; Pisu Maria Giuseppina; Mostallino Maria Cristina; Sanna Enrico; Biggio Giovanni
Changes in neuroactive steroid content during social isolation stress modulate GABAA receptor plasticity and function.
Brain research reviews 2008;57(2):520-30.
2008: Eva Carola; Mele Paolo; Collura Devis; Nai Antonella; Pisu Maria Giuseppina; Serra Mariangela; Biggio Giovanni
Modulation of neuropeptide Y and Y1 receptor expression in the amygdala by fluctuations in the brain content of neuroactive steroids during ethanol drinking discontinuation in Y1R/LacZ transgenic mice.
Journal of neurochemistry 2008;104(4):1043-54.
2007: Follesa Paolo; Biggio Francesca; Gorini Giorgio; Caria Stefania; Talani Giuseppe; Dazzi Laura; Puligheddu Monica; Marrosu Francesco; Biggio Giovanni
Vagus nerve stimulation increases norepinephrine concentration and the gene expression of BDNF and bFGF in the rat brain.
Brain research 2007;1179():28-34.
2007: Biggio Giovanni; Concas Alessandra; Follesa Paolo; Sanna Enrico; Serra Mariangela
Stress, ethanol, and neuroactive steroids.
Pharmacology & therapeutics 2007;116(1):140-71.
2007: Laquintana Valentino; Denora Nunzio; Lopedota Angela; Suzuki Hiromi; Sawada Makoto; Serra Mariangela; Biggio Giovanni; Latrofa Andrea; Trapani Giuseppe; Liso Gaetano
N-benzyl-2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(6-(7-nitrobenzo[c][1,2,5]oxadiazol-4-ylamino)hexyl)acetamide as a new fluorescent probe for peripheral benzodiazepine receptor and microglial cell visualization.
Bioconjugate chemistry 2007;18(5):1397-407.
2007: Denora Nunzio; Laquintana Valentino; Lopedota Angela; Serra Mariangela; Dazzi Laura; Biggio Giovanni; Pal Dhananjay; Mitra Ashim K; Latrofa Andrea; Trapani Giuseppe; Liso Gaetano
Novel L-Dopa and dopamine prodrugs containing a 2-phenyl-imidazopyridine moiety.
Pharmaceutical research 2007;24(7):1309-24.
2007: Dazzi Laura; Seu Emanuele; Cherchi Giulia; Barbieri Pier Paolo; Matzeu Alessandra; Biggio Giovanni
Estrous cycle-dependent changes in basal and ethanol-induced activity of cortical dopaminergic neurons in the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(4):892-901.
2007: Mascia Maria Paola; Bachis Elisabetta; Obili Nicola; Maciocco Elisabetta; Cocco Giovanni Antonio; Sechi Gian Pietro; Biggio Giovanni
Thiocolchicoside inhibits the activity of various subtypes of recombinant GABA(A) receptors expressed in Xenopus laevis oocytes.
European journal of pharmacology 2007;558(1-3):37-42.
2007: Serra M; Sanna E; Mostallino M C; Biggio G
Social isolation stress and neuroactive steroids.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2007;17(1):1-11.
2006: Mostallino Maria Cristina; Mura Maria Luisa; Maciocco Elisabetta; Murru Luca; Sanna Enrico; Biggio Giovanni
Changes in expression of the delta subunit of the GABA (A) receptor and in receptor function induced by progesterone exposure and withdrawal.
Journal of neurochemistry 2006;99(1):321-32.
2006: Pisu Maria Giuseppina; Floris Ivan; Maciocco Elisabetta; Serra Mariangela; Biggio Giovanni
Anticipation and consumption of food each increase the concentration of neuroactive steroids in rat brain and plasma.
Pharmacology, biochemistry, and behavior 2006;85(1):76-81.
2006: Carta Mario; Murru Luca; Botta Paolo; Talani Giuseppe; Sechi GianPietro; De Riu PierLuigi; Sanna Enrico; Biggio Giovanni
The muscle relaxant thiocolchicoside is an antagonist of GABAA receptor function in the central nervous system.
Neuropharmacology 2006;51(4):805-15.
2006: Hardoy Maria Carolina; Serra Mariangela; Carta Mauro Giovanni; Contu Paolo; Pisu Maria Giuseppina; Biggio Giovanni
Increased neuroactive steroid concentrations in women with bipolar disorder or major depressive disorder.
Journal of clinical psychopharmacology 2006;26(4):379-84.
2006: Rapkin Andrea J; Biggio Giovanni; Concas Alessandra
Oral contraceptives and neuroactive steroids.
Pharmacology, biochemistry, and behavior 2006;84(4):628-34.
2006: Eva Carola; Oberto Alessandra; Mele Paolo; Serra Mariangela; Biggio Giovanni
Role of brain neuroactive steroids in the functional interplay between the GABA(A) and the NPY-Y1 receptor mediated signals in the amygdala.
Pharmacology, biochemistry, and behavior 2006;84(4):568-80.
2006: Serra Mariangela; Mostallino Maria Cristina; Talani Giuseppe; Pisu Maria Giuseppina; Carta Mario; Mura Maria Luisa; Floris Ivan; Maciocco Elisabetta; Sanna Enrico; Biggio Giovanni
Social isolation-induced increase in alpha and delta subunit gene expression is associated with a greater efficacy of ethanol on steroidogenesis and GABA receptor function.
Journal of neurochemistry 2006;98(1):122-33.
2006: Pillai Rita; Scintu Franca; Scorciapino Laura; Carta Mario; Murru Luca; Biggio Giovanni; Cabras Stefano; Reali Camilla; Sogos Valeria
Human astrocytes can be induced to differentiate into cells with neuronal phenotype.
Experimental cell research 2006;312(12):2336-46.
2006: Follesa Paolo; Biggio Francesca; Talani Giuseppe; Murru Luca; Serra Mariangela; Sanna Enrico; Biggio Giovanni
Neurosteroids, GABAA receptors, and ethanol dependence.
Psychopharmacology 2006;186(3):267-80.
2006: Concas Alessandra; Sogliano Cristiana; Porcu Patrizia; Marra Carla; Brundu Andrea; Biggio Giovanni
Neurosteroids in nicotine and morphine dependence.
Psychopharmacology 2006;186(3):281-92.
2006: Rapkin Andrea J; Morgan Melinda; Sogliano Cristiana; Biggio Giovanni; Concas Alessandra
Decreased neuroactive steroids induced by combined oral contraceptive pills are not associated with mood changes.
Fertility and sterility 2006;85(5):1371-8.
2006: Paoletti Anna Maria; Romagnino Sandra; Contu Rossana; Orrù Marisa Margherita; Marotto Maria Francesca; Zedda Pierina; Lello Stefano; Biggio Giovanni; Concas Alessandra; Melis Gian Benedetto
Observational study on the stability of the psychological status during normal pregnancy and increased blood levels of neuroactive steroids with GABA-A receptor agonist activity.
Psychoneuroendocrinology 2006;31(4):485-92.
2005: Serra M; Pisu M G; Floris I; Biggio G
Social isolation-induced changes in the hypothalamic-pituitary-adrenal axis in the rat.
Stress (Amsterdam, Netherlands) 2005;8(4):259-64.
2005: Sanna Enrico; Busonero Fabio; Talani Giuseppe; Mostallino Maria Cristina; Mura Maria Luisa; Pisu Maria Giuseppina; Maciocco Elisabetta; Serra Mariangela; Biggio Giovanni
Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates.
European journal of pharmacology 2005;519(1-2):31-42.
2005: Marrosu F; Santoni F; Puligheddu M; Barberini L; Maleci A; Ennas F; Mascia M; Zanetti G; Tuveri A; Biggio G
Increase in 20-50 Hz (gamma frequencies) power spectrum and synchronization after chronic vagal nerve stimulation.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2005;116(9):2026-36.
2005: Follesa Paolo; Mostallino Maria Cristina; Biggio Francesca; Gorini Giorgio; Caria Stefania; Busonero Fabio; Murru Luca; Mura Maria Luisa; Sanna Enrico; Biggio Giovanni
Distinct patterns of expression and regulation of GABA receptors containing the delta subunit in cerebellar granule and hippocampal neurons.
Journal of neurochemistry 2005;94(3):659-71.
2005: Mascia Maria Paola; Asproni Battistina; Busonero Fabio; Talani Giuseppe; Maciocco Elisabetta; Pau Amedeo; Cerri Riccardo; Sanna Enrico; Biggio Giovanni
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
European journal of pharmacology 2005;516(3):204-11.
2005: Ferlin Maria Grazia; Chiarelotto Gianfranco; Dall'Acqua Stefano; Maciocco Elisabetta; Mascia Maria Paola; Pisu Maria Giuseppina; Biggio Giovanni
Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity.
Bioorganic & medicinal chemistry 2005;13(10):3531-41.
2005: Dazzi Laura; Seu Emanuele; Cherchi Giulia; Biggio Giovanni
Chronic administration of the SSRI fluvoxamine markedly and selectively reduces the sensitivity of cortical serotonergic neurons to footshock stress.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2005;15(3):283-90.
2005: Asproni Battistina; Talani Giuseppe; Busonero Fabio; Pau Amedeo; Sanna Sebastiano; Cerri Riccardo; Mascia Maria Paola; Sanna Enrico; Biggio Giovanni
Synthesis, structure-activity relationships at the GABA(A) receptor in rat brain, and differential electrophysiological profile at the recombinant human GABA(A) receptor of a series of substituted 1,2-diphenylimidazoles.
Journal of medicinal chemistry 2005;48(7):2638-45.
2005: Trapani Giuseppe; Laquintana Valentino; Denora Nunzio; Trapani Adriana; Lopedota Angela; Latrofa Andrea; Franco Massimo; Serra Mariangela; Pisu Maria Giuseppina; Floris Ivan; Sanna Enrico; Biggio Giovanni; Liso Gaetano
Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands.
Journal of medicinal chemistry 2005;48(1):292-305.
2004: Follesa Paolo; Biggio Francesca; Caria Stefania; Gorini Giorgio; Biggio Giovanni
Modulation of GABA(A) receptor gene expression by allopregnanolone and ethanol.
European journal of pharmacology 2004;500(1-3):413-25.
2004: Sanna Enrico; Talani Giuseppe; Busonero Fabio; Pisu Maria Giuseppina; Purdy Robert H; Serra Mariangela; Biggio Giovanni
Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(29):6521-30.
2004: Serra Mariangela; Pisu M Giuseppina; Floris Ivan; Floris Silvia; Cannas Emanuela; Mossa Alessandra; Trapani Giuseppe; Latrofa Andrea; Purdy Robert H; Biggio Giovanni
Social isolation increases the response of peripheral benzodiazepine receptors in the rat.
Neurochemistry international 2004;45(1):141-8.
2004: Mostallino Maria Cristina; Mascia Maria Paola; Pisu Maria Giuseppina; Busonero Fabio; Talani Giuseppe; Biggio Giovanni
Inhibition by miltirone of up-regulation of GABAA receptor alpha4 subunit mRNA by ethanol withdrawal in hippocampal neurons.
European journal of pharmacology 2004;494(2-3):83-90.
2004: Mele Paolo; Oberto Alessandra; Serra Mariangela; Pisu Maria Giuseppina; Floris Ivan; Biggio Giovanni; Eva Carola
Increased expression of the gene for the Y1 receptor of neuropeptide Y in the amygdala and paraventricular nucleus of Y1R/LacZ transgenic mice in response to restraint stress.
Journal of neurochemistry 2004;89(6):1471-8.
2004: Porcu Patrizia; Sogliano Cristiana; Ibba Cristina; Piredda Massimo; Tocco Silvia; Marra Carla; Purdy Robert H; Biggio Giovanni; Concas Alessandra
Failure of gamma-hydroxybutyric acid both to increase neuroactive steroid concentrations in adrenalectomized-orchiectomized rats and to induce tolerance to its steroidogenic effect in intact animals.
Brain research 2004;1012(1-2):160-8.
2004: Paoletti Anna Maria; Lello Stefano; Fratta Stefania; Orrù Marisa; Ranuzzi Francesca; Sogliano Cristiana; Concas Alessandra; Biggio Giovanni; Melis Gian Benedetto
Psychological effect of the oral contraceptive formulation containing 3 mg of drospirenone plus 30 microg of ethinyl estradiol.
Fertility and sterility 2004;81(3):645-51.
2004: Dazzi Laura; Seu Emanuele; Cherchi Giulia; Biggio Giovanni
Inhibition of stress-induced dopamine output in the rat prefrontal cortex by chronic treatment with olanzapine.
Biological psychiatry 2004;55(5):477-83.
2004: Trapani G; Cutrignelli A; Latrofa A; Franco M; Serra M; Pisu M G; Biggio G; Liso G
Valproic acid-hydrophilic cyclodextrin complexes and valproic acid-solid dispersions: evaluation of their potential pharmaceutical use.
Drug development and industrial pharmacy 2004;30(1):53-64.
2004: Follesa Paolo; Biggio Francesca; Mancuso Luisa; Cabras Stefano; Caria Stefania; Gorini Giorgio; Manca Annalisa; Orru Alessandro; Biggio Giovanni
Ethanol withdrawal-induced up-regulation of the alpha2 subunit of the GABAA receptor and its prevention by diazepam or gamma-hydroxybutyric acid.
Brain research. Molecular brain research 2004;120(2):130-7.
2003: Sanna Enrico; Mostallino Maria Cristina; Busonero Fabio; Talani Giuseppe; Tranquilli Stefania; Mameli Manuel; Spiga Saturnino; Follesa Paolo; Biggio Giovanni
Changes in GABA(A) receptor gene expression associated with selective alterations in receptor function and pharmacology after ethanol withdrawal.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(37):11711-24.
2003: Biggio Giovanni; Dazzi Laura; Biggio Francesca; Mancuso Luisa; Talani Giuseppe; Busonero Fabio; Mostallino Maria Cristina; Sanna Enrico; Follesa Paolo
Molecular mechanisms of tolerance to and withdrawal of GABA(A) receptor modulators.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(6):411-23.
2003: Carotti Andrea; Altomare Cosimo; Savini Luisa; Chiasserini Luisa; Pellerano Cesare; Mascia Maria P; Maciocco Elisabetta; Busonero Fabio; Mameli Manuel; Biggio Giovanni; Sanna Enrico
High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones.
Bioorganic & medicinal chemistry 2003;11(23):5259-72.
2003: Altomare Cosimo; Trapani Giuseppe; Latrofa Andrea; Serra Mariangela; Sanna Enrico; Biggio Giovanni; Liso Gaetano
Highly water-soluble derivatives of the anesthetic agent propofol: in vitro and in vivo evaluation of cyclic amino acid esters.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;20(1):17-26.
2003: Dazzi Laura; Seu Emanuele; Cherchi Giulia; Biggio Giovanni
Antagonism of the stress-induced increase in cortical norepinephrine output by the selective norepinephrine reuptake inhibitor reboxetine.
European journal of pharmacology 2003;476(1-2):55-61.
2003: Cappelli Andrea; Pericot Mohr Gal la; Gallelli Andrea; Giuliani Germano; Anzini Maurizio; Vomero Salvatore; Fresta Massimo; Porcu Patrizia; Maciocco Elisabetta; Concas Alessandra; Biggio Giovanni; Donati Alessandro
Structure-activity relationships in carboxamide derivatives based on the targeted delivery of radionuclides and boron atoms by means of peripheral benzodiazepine receptor ligands.
Journal of medicinal chemistry 2003;46(17):3568-71.
2003: Trapani Giuseppe; Laquintana Valentino; Latrofa Andrea; Ma Jianguo; Reed Karin; Serra Mariangela; Biggio Giovanni; Liso Gaetano; Gallo James M
Peripheral benzodiazepine receptor ligand-melphalan conjugates for potential selective drug delivery to brain tumors.
Bioconjugate chemistry 2003;14(4):830-9.
2003: Marrosu Francesco; Serra Alessandra; Maleci Alberto; Puligheddu Monica; Biggio Giovanni; Piga Mario
Correlation between GABA(A) receptor density and vagus nerve stimulation in individuals with drug-resistant partial epilepsy.
Epilepsy research 2003;55(1-2):59-70.
2003: Follesa Paolo; Mancuso Luisa; Biggio Francesca; Mostallino Maria Cristina; Manca Annalisa; Mascia Maria Paola; Busonero Fabio; Talani Giuseppe; Sanna Enrico; Biggio Giovanni
Gamma-hydroxybutyric acid and diazepam antagonize a rapid increase in GABA(A) receptors alpha(4) subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells.
Molecular pharmacology 2003;63(4):896-907.
2003: Serra Mariangela; Pisu M Giuseppina; Floris Ivan; Cara Valeria; Purdy Robert H; Biggio Giovanni
Social isolation-induced increase in the sensitivity of rats to the steroidogenic effect of ethanol.
Journal of neurochemistry 2003;85(1):257-63.
2003: Trapani Giuseppe; Latrofa Andrea; Franco Massimo; Carrieri Antonio; Cellamare Saverio; Serra Mariangela; Sanna Enrico; Biggio Giovanni; Liso Gaetano
Alpidem analogues containing a GABA or glycine moiety as new anticonvulsant agents.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;18(3-4):231-40.
2003: Porcu Patrizia; Sogliano Cristiana; Cinus Monica; Purdy Robert H; Biggio Giovanni; Concas Alessandra
Nicotine-induced changes in cerebrocortical neuroactive steroids and plasma corticosterone concentrations in the rat.
Pharmacology, biochemistry, and behavior 2003;74(3):683-90.
2003: Gupta Maneesh; Hogema Boris M; Grompe Markus; Bottiglieri Teodoro G; Concas Alessandra; Biggio Giovanni; Sogliano Cristiana; Rigamonti Antonello E; Pearl Phillip L; Snead O Carter; Jakobs Cornelis; Gibson K Michael
Murine succinate semialdehyde dehydrogenase deficiency.
Annals of neurology 2003;54 Suppl 6():S81-90.
2002: Mascia Maria Paola; Biggio Francesca; Mancuso Luisa; Cabras Stefano; Cocco Pier Luigi; Gorini Giorgio; Manca Annalisa; Marra Carla; Purdy Robert H; Follesa Paolo; Biggio Giovanni
Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, ganaxolone in cultured rat cerebellar granule cells.
The Journal of pharmacology and experimental therapeutics 2002;303(3):1014-20.
2002: Dazzi Laura; Serra Mariangela; Seu Emanuele; Cherchi Giulia; Pisu M Giuseppina; Purdy Robert H; Biggio Giovanni
Progesterone enhances ethanol-induced modulation of mesocortical dopamine neurons: antagonism by finasteride.
Journal of neurochemistry 2002;83(5):1103-9.
2002: Asproni Battistina; Pau Amedeo; Bitti Mauro; Melosu Marilena; Cerri Riccardo; Dazzi Laura; Seu Emanuele; Maciocco Elisabetta; Sanna Enrico; Busonero Fabio; Talani Giuseppe; Pusceddu Luca; Altomare Cosimo; Trapani Giuseppe; Biggio Giovanni
Synthesis and pharmacological evaluation of 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-phenylpiperazines with clozapine-like mixed activities at dopamine D(2), serotonin, and GABA(A) receptors.
Journal of medicinal chemistry 2002;45(21):4655-68.
2002: Oberto Alessandra; Serra Mariangela; Pisu Maria Giuseppina; Biggio Giovanni; Eva Carola
Changes in expression of the neuropeptide Y Y1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery.
Journal of neurochemistry 2002;82(5):1272-81.
2002: Sanna Enrico; Busonero Fabio; Talani Giuseppe; Carta Mario; Massa Federico; Peis Michela; Maciocco Elisabetta; Biggio Giovanni
Comparison of the effects of zaleplon, zolpidem, and triazolam at various GABA(A) receptor subtypes.
European journal of pharmacology 2002;451(2):103-10.
2002: Serra Mariangela; Pisul M Giuseppina; Dazzi Laura; Purdy Robert H; Biggio Giovanni
Prevention of the stress-induced increase in the concentration of neuroactive steroids in rat brain by long-term administration of mirtazapine but not of fluoxetine.
Journal of psychopharmacology (Oxford, England) 2002;16(2):133-8.
2002: Dazzi Laura; Vignone Vincenzo; Seu Emanuele; Ladu Stefania; Vacca Giada; Biggio Giovanni
Inhibition by venlafaxine of the increase in norepinephrine output in rat prefrontal cortex elicited by acute stress or by the anxiogenic drug FG 7142.
Journal of psychopharmacology (Oxford, England) 2002;16(2):125-31.
2002: Trapani Giuseppe; Dazzi Laura; Pisu Maria Giuseppina; Reho Antonia; Seu Emanuele; Biggio Giovanni
A rapid method for obtaining finasteride, a 5alpha-reductase inhibitor, from commercial tablets.
Brain research. Brain research protocols 2002;9(2):130-4.
2002: Dazzi Laura; Serra Mariangela; Vacca Giada; Ladu Stefania; Latrofa Andrea; Trapani Giuseppe; Biggio Giovanni
Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output.
Brain research 2002;932(1-2):135-9.
2002: Follesa P; Porcu P; Sogliano C; Cinus M; Biggio F; Mancuso L; Mostallino M C; Paoletti A M; Purdy R H; Biggio G; Concas A
Changes in GABAA receptor gamma 2 subunit gene expression induced by long-term administration of oral contraceptives in rats.
Neuropharmacology 2002;42(3):325-36.
2002: Follesa P; Mancuso L; Biggio F; Cagetti E; Franco M; Trapani G; Biggio G
Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, zaleplon or zolpidem.
Neuropharmacology 2002;42(2):191-8.
2002: Dazzi Laura; Ladu Stefania; Spiga Francesca; Vacca Giada; Rivano Antonella; Pira Luigi; Biggio Giovanni
Chronic treatment with imipramine or mirtazapine antagonizes stress- and FG7142-induced increase in cortical norepinephrine output in freely moving rats.
Synapse (New York, N.Y.) 2002;43(1):70-7.
2001: Pisu M G; Papi G; Porcu P; Trapani G; Latrofa A; Biggio G; Serra M
Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes.
European journal of pharmacology 2001;432(2-3):129-34.
2001: Pierobon P; Minei R; Porcu P; Sogliano C; Tino A; Marino G; Biggio G; Concas A
Putative glycine receptors in Hydra: a biochemical and behavioural study.
The European journal of neuroscience 2001;14(10):1659-66.
2001: Follesa P; Concas A; Porcu P; Sanna E; Serra M; Mostallino M C; Purdy R H; Biggio G
Role of allopregnanolone in regulation of GABA(A) receptor plasticity during long-term exposure to and withdrawal from progesterone.
Brain research. Brain research reviews 2001;37(1-3):81-90.
2001: Serra M; Pisu M G; Muggironi M; Parodo V; Papi G; Sari R; Dazzi L; Spiga F; Purdy R H; Biggio G
Opposite effects of short- versus long-term administration of fluoxetine on the concentrations of neuroactive steroids in rat plasma and brain.
Psychopharmacology 2001;158(1):48-54.
2001: Ferrara G; Serra M; Zammaretti F; Pisu M G; Panzica G C; Biggio G; Eva C
Increased expression of the neuropeptide Y receptor Y(1) gene in the medial amygdala of transgenic mice induced by long-term treatment with progesterone or allopregnanolone.
Journal of neurochemistry 2001;79(2):417-25.
2001: Dazzi L; Serra M; Spiga F; Pisu M G; Jentsch J D; Biggio G
Prevention of the stress-induced increase in frontal cortical dopamine efflux of freely moving rats by long-term treatment with antidepressant drugs.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2001;11(5):343-9.
2001: Barbaccia M L; Affricano D; Purdy R H; Maciocco E; Spiga F; Biggio G
Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(4):489-97.
2001: Franco M; Trapani G; Latrofa A; Tullio C; Provenzano M R; Serra M; Muggironi M; Biggio G; Liso G
Dissolution properties and anticonvulsant activity of phenytoin-polyethylene glycol 6000 and -polyvinylpyrrolidone K-30 solid dispersions.
International journal of pharmaceutics 2001;225(1-2):63-73.
2001: Dazzi L; Vacca G; Ladu S; Pisu M G; Serra M; Biggio G
Long-term treatment with antidepressant drugs reduces the sensitivity of cortical cholinergic neurons to the activating actions of stress and the anxiogenic drug FG 7142.
Neuropharmacology 2001;41(2):229-37.
2001: Follesa P; Cagetti E; Mancuso L; Biggio F; Manca A; Maciocco E; Massa F; Desole M S; Carta M; Busonero F; Sanna E; Biggio G
Increase in expression of the GABA(A) receptor alpha(4) subunit gene induced by withdrawal of, but not by long-term treatment with, benzodiazepine full or partial agonists.
Brain research. Molecular brain research 2001;92(1-2):138-48.
2001: Rasgon N; Serra M; Biggio G; Pisu M G; Fairbanks L; Tanavoli S; Rapkin A
Neuroactive steroid-serotonergic interaction: responses to an intravenous L-tryptophan challenge in women with premenstrual syndrome.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(1):25-33.
2001: Savini L; Chiasserini L; Pellerano C; Biggio G; Maciocco E; Serra M; Cinone N; Carrieri A; Altomare C; Carotti A
High affinity central benzodiazepine receptor ligands. Part 2: quantitative structure-activity relationships and comparative molecular field analysis of pyrazolo[4,3-c]quinolin-3-ones.
Bioorganic & medicinal chemistry 2001;9(2):431-44.
2001: Dazzi L; Spiga F; Pira L; Ladu S; Vacca G; Rivano A; Jentsch J D; Biggio G
Inhibition of stress- or anxiogenic-drug-induced increases in dopamine release in the rat prefrontal cortex by long-term treatment with antidepressant drugs.
Journal of neurochemistry 2001;76(4):1212-20.
2001: Barbaccia M L; Serra M; Purdy R H; Biggio G
Stress and neuroactive steroids.
International review of neurobiology 2001;46():243-72.
2001: Biggio G; Follesa P; Sanna E; Purdy R H; Concas A
GABAA-receptor plasticity during long-term exposure to and withdrawal from progesterone.
International review of neurobiology 2001;46():207-41.
2000: Follesa P; Cagetti E; Porta S; Espositoto G; Biggio G
Pivagabine-induced increases in the abundance of CRF mRNA in the cerebral cortex and hypothalamus of rats.
Brain research. Molecular brain research 2000;84(1-2):52-7.
2000: Serra M; Littera M; Pisu M G; Muggironi M; Purdy R H; Biggio G
Steroidogenesis in rat brain induced by short- and long-term administration of carbamazepine.
Neuropharmacology 2000;39(12):2448-56.
2000: Serra M; Pisu M G; Littera M; Papi G; Sanna E; Tuveri F; Usala L; Purdy R H; Biggio G
Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain.
Journal of neurochemistry 2000;75(2):732-40.
2000: Follesa P; Serra M; Cagetti E; Pisu M G; Porta S; Floris S; Massa F; Sanna E; Biggio G
Allopregnanolone synthesis in cerebellar granule cells: roles in regulation of GABA(A) receptor expression and function during progesterone treatment and withdrawal.
Molecular pharmacology 2000;57(6):1262-70.
2000: Concas A; Porcu P; Sogliano C; Serra M; Purdy R H; Biggio G
Caffeine-induced increases in the brain and plasma concentrations of neuroactive steroids in the rat.
Pharmacology, biochemistry, and behavior 2000;66(1):39-45.
2000: Trapani G; Altomare C; Liso G; Sanna E; Biggio G
Propofol in anesthesia. Mechanism of action, structure-activity relationships, and drug delivery.
Current medicinal chemistry 2000;7(2):249-71.
1999: Trapani G; Franco M; Latrofa A; Ricciardi L; Carotti A; Serra M; Sanna E; Biggio G; Liso G
Novel 2-phenylimidazo[1,2-a]pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies.
Journal of medicinal chemistry 1999;42(19):3934-41.
1999: Serra M; Dazzi L; Caddeo M; Floris C; Biggio G
Reversal by flunarizine of the decrease in hippocampal acetylcholine release in pentylenetetrazole-kindled rats.
Biochemical pharmacology 1999;58(1):145-9.
1999: Concas A; Follesa P; Barbaccia M L; Purdy R H; Biggio G
Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites.
European journal of pharmacology 1999;375(1-3):225-35.
1999: Follesa P; Tarantino A; Floris S; Mallei A; Porta S; Tuligi G; Cagetti E; Caddeo M; Mura A; Serra M; Biggio G
Changes in the gene expression of GABAA receptor subunit mRNAs in the septum of rats subjected to pentylenetetrazol-induced kindling.
Brain research. Molecular brain research 1999;70(1):1-8.
1999: Serra M; Madau P; Chessa M F; Caddeo M; Sanna E; Trapani G; Franco M; Liso G; Purdy R H; Barbaccia M L; Biggio G
2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats.
British journal of pharmacology 1999;127(1):177-87.
1999: Serra M; Concas A; Mostallino M C; Chessa M F; Stomati M; Petraglia F; Genazzani A R; Biggio G
Antagonism by pivagabine of stress-induced changes in GABAA receptor function and corticotropin-releasing factor concentrations in rat brain.
Psychoneuroendocrinology 1999;24(3):269-84.
1999: Sanna E; Motzo C; Usala M; Serra M; Dazzi L; Maciocco E; Trapani G; Latrofa A; Liso G; Biggio G
Characterization of the electrophysiological and pharmacological effects of 4-iodo-2,6-diisopropylphenol, a propofol analogue devoid of sedative-anaesthetic properties.
British journal of pharmacology 1999;126(6):1444-54.
1999: Sanna E; Pau D; Tuveri F; Massa F; Maciocco E; Acquas C; Floris C; Fontana S N; Maira G; Biggio G
Molecular and neurochemical evaluation of the effects of etizolam on GABAA receptors under normal and stress conditions.
Arzneimittel-Forschung 1999;49(2):88-95.
1999: Follesa P; Mallei A; Floris S; Mostallino M C; Sanna E; Biggio G
Increased abundance of GABAA receptor subunit mRNAs in the brain of Long-Evans Cinnamon rats, an animal model of Wilson's disease.
Brain research. Molecular brain research 1999;63(2):268-75.
1998: Barbaccia M L; Concas A; Serra M; Biggio G
Stress and neurosteroids in adult and aged rats.
Experimental gerontology 1998;33(7-8):697-712.
1998: Concas A; Mostallino M C; Porcu P; Follesa P; Barbaccia M L; Trabucchi M; Purdy R H; Grisenti P; Biggio G
Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13284-9.
1998: Follesa P; Floris S; Tuligi G; Mostallino M C; Concas A; Biggio G
Molecular and functional adaptation of the GABA(A) receptor complex during pregnancy and after delivery in the rat brain.
The European journal of neuroscience 1998;10(9):2905-12.
1998: Concas A; Pierobon P; Mostallino M C; Porcu P; Marino G; Minei R; Biggio G
Modulation of gamma-aminobutyric acid (GABA) receptors and the feeding response by neurosteroids in Hydra vulgaris.
Neuroscience 1998;85(3):979-88.
1998: Sanna E; Motzo C; Usala M; Pau D; Cagetti E; Biggio G
Functional changes in rat nigral GABA(A) receptors induced by degeneration of the striatonigral GABAergic pathway: an electrophysiological study of receptors incorporated into Xenopus oocytes.
Journal of neurochemistry 1998;70(6):2539-44.
1998: Trapani G; Latrofa A; Franco M; Altomare C; Sanna E; Usala M; Biggio G; Liso G
Propofol analogues. Synthesis, relationships between structure and affinity at GABAA receptor in rat brain, and differential electrophysiological profile at recombinant human GABAA receptors.
Journal of medicinal chemistry 1998;41(11):1846-54.
1998: Savini L; Massarelli P; Nencini C; Pellerano C; Biggio G; Maciocco A; Tuligi G; Carrieri A; Cinone N; Carotti A
High affinity central benzodiazepine receptor ligands: synthesis and structure-activity relationship studies of a new series of pyrazolo[4,3-c]quinolin-3-ones.
Bioorganic & medicinal chemistry 1998;6(4):389-99.
1998: Ghiani C A; Dazzi L; Maciocco E; Flore G; Maira G; Biggio G
Antagonism by abecarnil of enhanced acetylcholine release in the rat brain during anticipation but not consumption of food.
Pharmacology, biochemistry, and behavior 1998;59(3):657-62.
1998: Imperato A; Dazzi L; Carta G; Colombo G; Biggio G
Rapid increase in basal acetylcholine release in the hippocampus of freely moving rats induced by withdrawal from long-term ethanol intoxication.
Brain research 1998;784(1-2):347-50.
1997: Trapani G; Franco M; Ricciardi L; Latrofa A; Genchi G; Sanna E; Tuveri F; Cagetti E; Biggio G; Liso G
Synthesis and binding affinity of 2-phenylimidazo[1,2-alpha]pyridine derivatives for both central and peripheral benzodiazepine receptors. A new series of high-affinity and selective ligands for the peripheral type.
Journal of medicinal chemistry 1997;40(19):3109-18.
1997: Dazzi L; Serra M; Porceddu M L; Sanna A; Chessa M F; Biggio G
Enhancement of basal and pentylenetetrazol (PTZ)-stimulated dopamine release in the brain of freely moving rats by PTZ-induced kindling.
Synapse (New York, N.Y.) 1997;26(4):351-8.
1997: Serra M; Cuccu R; Ghiani C A; Pisu M G; Murgia A; Biggio G
Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam.
Neurochemical research 1997;22(6):693-7.
1997: Motzo C; Porceddu M L; Dazzi L; Sanna A; Serra M; Biggio G
Enhancement by flumazenil of dopamine release in the nucleus accumbens of rats repeatedly exposed to diazepam or imidazenil.
Psychopharmacology 1997;131(1):34-9.
1997: Padiglia A; Medda R; Lorrai A; Biggio G; Sanna E; Floris G
Modulation of 6-hydroxydopamine oxidation by various proteins.
Biochemical pharmacology 1997;53(8):1065-8.
1997: Barbaccia M L; Roscetti G; Trabucchi M; Purdy R H; Mostallino M C; Concas A; Biggio G
The effects of inhibitors of GABAergic transmission and stress on brain and plasma allopregnanolone concentrations.
British journal of pharmacology 1997;120(8):1582-8.
1997: Serra M; Dazzi L; Pisu M G; Cagetti E; Biggio G
Reversal of a selective decrease in hippocampal acetylcholine release, but not of the persistence of kindling, after discontinuation of long-term pentylenetetrazol administration in rats.
Brain research 1997;751(1):175-9.
1997: Sanna E; Murgia A; Casula A; Biggio G
Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes.
Molecular pharmacology 1997;51(3):484-90.
1997: Serra M; Dazzi L; Cagetti E; Chessa M F; Pisu M G; Sanna A; Biggio G
Effect of pentylenetetrazole-induced kindling on acetylcholine release in the hippocampus of freely moving rats.
Journal of neurochemistry 1997;68(1):313-8.
1996: Sanna E; Motzo C; Murgia A; Amato F; Deserra T; Biggio G
Expression of native GABAA receptors in Xenopus oocytes injected with rat brain synaptosomes.
Journal of neurochemistry 1996;67(5):2212-4.
1996: Trapani G; Franco M; Latrofa A; Carotti A; Cellamare S; Serra M; Ghiani C A; Tuligi G; Biggio G; Liso G
Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolo[2,1-b]-benzothiazol-, -thiazol- or -oxazol-1-ones in rodents.
The Journal of pharmacy and pharmacology 1996;48(8):834-40.
1996: Concas A; Mostallino M C; Perra C; Lener R; Roscetti G; Barbaccia M L; Purdy R H; Biggio G
Functional correlation between allopregnanolone and [35S]-TBPS binding in the brain of rats exposed to isoniazid, pentylenetetrazol or stress.
British journal of pharmacology 1996;118(4):839-46.
1996: Ghiani C A; Tuligi G; Maciocco E; Serra M; Sanna E; Biggio G
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
Biochemical pharmacology 1996;51(11):1527-34.
1996: Barbaccia M L; Roscetti G; Bolacchi F; Concas A; Mostallino M C; Purdy R H; Biggio G
Stress-induced increase in brain neuroactive steroids: antagonism by abecarnil.
Pharmacology, biochemistry, and behavior 1996;54(1):205-10.
1996: Barbaccia M L; Roscetti G; Trabucchi M; Mostallino M C; Concas A; Purdy R H; Biggio G
Time-dependent changes in rat brain neuroactive steroid concentrations and GABAA receptor function after acute stress.
Neuroendocrinology 1996;63(2):166-72.
1996: Dazzi L; Sanna A; Cagetti E; Concas A; Biggio G
Inhibition by the neurosteroid allopregnanolone of basal and stress-induced acetylcholine release in the brain of freely moving rats.
Brain research 1996;710(1-2):275-80.
1996: Concas A; Mascia M P; Cuccheddu T; Floris S; Mostallino M C; Perra C; Satta S; Biggio G
Chronic ethanol intoxication enhances [3H]CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum.
Pharmacology, biochemistry, and behavior 1996;53(2):249-55.
1996: Sanna E; Murgia A; Casula A; Usala M; Maciocco E; Tuligi G; Biggio G
Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit.
Neuropharmacology 1996;35(12):1753-60.
1996: Barbaccia M L; Roscetti G; Trabucchi M; Purdy R H; Mostallino M C; Perra C; Concas A; Biggio G
Isoniazid-induced inhibition of GABAergic transmission enhances neurosteroid content in the rat brain.
Neuropharmacology 1996;35(9-10):1299-305.
1995: Serra M; Ghiani C A; Motzo C; Porceddu M L; Biggio G
Antagonism of isoniazid-induced convulsions by abecarnil in mice tolerant to diazepam.
Pharmacology, biochemistry, and behavior 1995;52(2):249-54.
1995: Dazzi L; Motzo C; Maira G; Sanna A; Serra M; Biggio G
Enhancement of acetylcholine release by flumazenil in the hippocampus of rats chronically treated with diazepam but not with imidazenil or abecarnil.
Psychopharmacology 1995;121(2):180-5.
1995: Dazzi L; Motzo C; Imperato A; Serra M; Gessa G L; Biggio G
Modulation of basal and stress-induced release of acetylcholine and dopamine in rat brain by abecarnil and imidazenil, two anxioselective gamma-aminobutyric acidA receptor modulators.
The Journal of pharmacology and experimental therapeutics 1995;273(1):241-7.
1995: Cuccheddu T; Floris S; Serra M; Porceddu M L; Sanna E; Biggio G
Proconflict effect of carbon dioxide inhalation in rats.
Life sciences 1995;56(16):PL321-4.
1995: Pierobon P; Concas A; Santoro G; Marino G; Minei R; Pannaccione A; Mostallino M C; Biggio G
Biochemical and functional identification of GABA receptors in Hydra vulgaris.
Life sciences 1995;56(18):1485-97.
1994: Serra M; Ghiani C A; Spano S; Biggio G
Felbamate antagonizes isoniazid- and FG 7142-induced reduction of GABAA receptor function in mouse brain.
European journal of pharmacology 1994;265(3):185-8.
1994: Concas A; Serra M; Santoro G; Maciocco E; Cuccheddu T; Biggio G
The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines.
Naunyn-Schmiedeberg's archives of pharmacology 1994;350(3):294-300.
1994: Imperato A; Dazzi L; Serra M; Gessa G L; Biggio G
Differential effects of abecarnil on basal release of acetylcholine and dopamine in the rat brain.
European journal of pharmacology 1994;261(1-2):205-8.
1994: Barbaccia M L; Roscetti G; Trabucchi M; Cuccheddu T; Concas A; Biggio G
Neurosteroids in the brain of handling-habituated and naive rats: effect of CO2 inhalation.
European journal of pharmacology 1994;261(3):317-20.
1994: Serra M; Ghiani C A; Motzo C; Porceddu M L; Biggio G
Long-term treatment with abecarnil fails to induce tolerance in mice.
European journal of pharmacology 1994;259(1):1-6.
1994: Imperato A; Dazzi L; Obinu M C; Gessa G L; Biggio G
The benzodiazepine receptor antagonist flumazenil increases acetylcholine release in rat hippocampus.
Brain research 1994;647(1):167-71.
1994: Concas A; Cuccheddu T; Floris S; Mascia M P; Biggio G
2-Chloro-N6-cyclopentyladenosine (CCPA), an adenosine A1 receptor agonist, suppresses ethanol withdrawal syndrome in rats.
Alcohol and alcoholism (Oxford, Oxfordshire) 1994;29(3):261-4.
1994: Serra M; Ghiani C A; Motzo C; Cuccheddu T; Floris S; Giusti P; Biggio G
Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor function.
The Journal of pharmacology and experimental therapeutics 1994;269(1):32-8.
1994: Concas A; Santoro G; Mascia M P; Maciocco E; Dazzi L; Biggio G
Effects of propofol, pentobarbital and alphaxalone on t-[35S]butylbicyclophosphorothionate binding in rat cerebral cortex.
European journal of pharmacology 1994;267(2):207-13.
1994: Serra M; Ghiani C A; Foddi M C; Motzo C; Biggio G
NMDA receptor function is enhanced in the hippocampus of aged rats.
Neurochemical research 1994;19(4):483-7.
1994: Ghiani C A; Serra M; Motzo C; Giusti P; Cuccheddu T; Porceddu M L; Biggio G
Chronic administration of an anticonvulsant dose of imidazenil fails to induce tolerance of GABAA receptor function in mice.
European journal of pharmacology 1994;254(3):299-302.
1993: Concas A; Santoro G; Mascia M P; Maciocco E; Dazzi L; Ongini E; Biggio G
Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain.
The Journal of pharmacology and experimental therapeutics 1993;267(2):844-51.
1993: Imperato A; Dazzi L; Obinu M C; Gessa G L; Biggio G
Inhibition of hippocampal acetylcholine release by benzodiazepines: antagonism by flumazenil.
European journal of pharmacology 1993;238(1):135-7.
1993: Concas A; Sanna E; Cuccheddu T; Mascia M P; Santoro G; Maciocco E; Biggio G
Carbon dioxide inhalation, stress and anxiogenic drugs reduce the function of GABAA receptor complex in the rat brain.
Progress in neuro-psychopharmacology & biological psychiatry 1993;17(4):651-61.
1993: Sanna E; Serra M; Cossu A; Colombo G; Follesa P; Cuccheddu T; Concas A; Biggio G
Chronic ethanol intoxication induces differential effects on GABAA and NMDA receptor function in the rat brain.
Alcoholism, clinical and experimental research 1993;17(1):115-23.
1993: Serra M; Ghiani C A; Motzo C; Biggio G
Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors.
Psychopharmacology series 1993;11():62-78.
1992: Serra M; Foddi M C; Ghiani C A; Melis M A; Motzo C; Concas A; Sanna E; Biggio G
Pharmacology of gamma-aminobutyric acidA receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta-carboline derivative abecarnil.
The Journal of pharmacology and experimental therapeutics 1992;263(3):1360-8.
1992: Sanna E; Cuccheddu T; Serra M; Concas A; Biggio G
Carbon dioxide inhalation reduces the function of GABAA receptors in the rat brain.
European journal of pharmacology 1992;216(3):457-8.
1992: Giorgi O; Pibiri M G; Dal Toso R; Toffano G; Biggio G
Differential turnover rates of D1 dopamine receptors in the brain and retina of adult and senescent rats.
Neurochemistry international 1992;20 Suppl():171S-173S.
1992: Biggio G; Cibin M; Diana M; Fadda F; Ferrara S D; Gallimberti L; Gessa G L; Mereu G P; Rossetti Z L; Serra M
Suppression of voluntary alcohol intake in rats and alcoholics by gamma-hydroxybutyric acid: a non-GABAergic mechanism.
Advances in biochemical psychopharmacology 1992;47():281-8.
1992: Sanna E; Serra M; Cossu A; Colombo G; Follesa P; Biggio G
GABAA and NMDA receptor function during chronic administration of ethanol.
Advances in biochemical psychopharmacology 1992;47():317-24.
1992: Concas A; Santoro G; Mascia M P; Maciocco E; Biggio G
The general anesthetic propofol: a biochemical tool to study the function of the GABA-coupled chloride channel.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():685A-686A.
1992: Concas A; Serra M; Sanna E; Pepitoni S; Mascia M P; Biggio G
Involvement of GABA-dependent chloride channel in the action of anticonvulsant and convulsant drugs.
Epilepsy research. Supplement 1992;8():77-85.
1992: Concas A; Santoro G; Mascia M P; Serra M; Sanna E; Biggio G
The action of the general anesthetic propofol on GABAA receptors.
Advances in biochemical psychopharmacology 1992;47():349-63.
1991: Peduto V A; Concas A; Santoro G; Biggio G; Gessa G L
Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain.
Anesthesiology 1991;75(6):1000-9.
1991: Giorgi O; Pibiri M G; Biggio G
Differential turnover rates of D1 dopamine receptors in the retina and in distinct areas of the rat brain.
Journal of neurochemistry 1991;57(3):754-9.
1991: Giorgi O; Pibiri M G; Ongini E; Trampus M; Biggio G
The neutral endopeptidase-24.11 (enkephalinase) inhibitor, SCH 32615, increases dopamine metabolism in the nucleus accumbens of the rat.
European journal of pharmacology 1991;196(2):137-42.
1991: Concas A; Santoro G; Serra M; Sanna E; Biggio G
Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors.
Brain research 1991;542(2):225-32.
1991: Sanna E; Concas A; Serra M; Santoro G; Biggio G
Ex vivo binding of t-[35S )butylbicyclophosphorothionate: a biochemical tool to study the pharmacology of ethanol at the gamma-aminobutyric acid-coupled chloride channel.
The Journal of pharmacology and experimental therapeutics 1991;256(3):922-8.
1991: Concas A; Mascia M P; Sanna E; Santoro G; Serra M; Biggio G
"In vivo" administration of valproate decreases t-[35S]butylbicyclophosphorothionate binding in the rat brain.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(3):296-300.
1991: Serra M; Sanna E; Concas A; Foddi C; Biggio G
Foot-shock stress enhances the increase of [35S]TBPS binding in the rat cerebral cortex and the convulsions induced by isoniazid.
Neurochemical research 1991;16(1):17-22.
1991: Serra M; Sanna E; Foddi C; Concas A; Biggio G
Failure of gamma-hydroxybutyrate to alter the function of the GABAA receptor complex in the rat cerebral cortex.
Psychopharmacology 1991;104(3):351-5.
1991: Biggio G; Sanna E; Serra M; Serra G P; Concas A
"In vivo" inhibition of GABAergic transmission increases 35S-TBPS binding in the rat brain.
Advances in experimental medicine and biology 1991;287():391-404.
1990: Concas A; Santoro G; Mascia M P; Serra M; Sanna E; Biggio G
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
Journal of neurochemistry 1990;55(6):2135-8.
1990: Giorgi O; Biggio G
Selective unilateral inactivation of striatal D1 and D2 dopamine receptor subtypes by EEDQ: turning behavior elicited by D2 dopamine receptor agonists.
Brain research 1990;533(1):53-9.
1990: Corda M G; Giorgi O; Longoni B; Orlandi M; Biggio G
Decrease in the function of the gamma-aminobutyric acid-coupled chloride channel produced by the repeated administration of pentylenetetrazol to rats.
Journal of neurochemistry 1990;55(4):1216-21.
1990: Sanna E; Concas A; Serra M; Biggio G
Enhancement of GABA-dependent chloride channel by "in vivo" administration of ethanol.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22 Suppl 1():91-2.
1990: Concas A; Sanna E; Mascia M P; Serra M; Biggio G
Diazepam enhances bicuculline-induced increase of t-[35S]butylbicyclophosphorothionate binding in unwashed membrane preparations from rat cerebral cortex.
Neuroscience letters 1990;112(1):87-91.
1990: Mereu G; Carcangiu G; Concas A; Passino N; Biggio G
Reduction of reticulata neuronal activity by zolpidem and alpidem, two imidazopyridines with high affinity for type I benzodiazepine receptors.
European journal of pharmacology 1990;179(3):339-45.
1990: Giorgi O; Biggio G
Unilateral inactivation of dopamine receptors after intrastriatal injection of N-ethoxy-carbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ): a novel rotational model to investigate dopamine receptor interactions.
Pharmacology, biochemistry, and behavior 1990;35(4):877-84.
1990: Porceddu M L; De Montis G; Pepitoni S; Toffano G; Biggio G
Failure of dark adaptation to upregulate D-1 dopamine receptors in retina of senescent rats.
Neurobiology of aging 1990;11(2):105-9.
1990: Sanna E; Concas A; Serra M; Biggio G
In vivo administration of ethanol enhances the function of the gamma-aminobutyric acid-dependent chloride channel in the rat cerebral cortex.
Journal of neurochemistry 1990;54(2):696-8.
1990: Giorgi O; Porceddu M L; Pepitoni S; Serra G P; Toffano G; Biggio G
Differential effect of aging on 3H-SCH 23390 binding sites in the retina and in distinct areas of the rat brain.
Journal of neural transmission. General section 1990;82(3):157-66.
1990: Concas A; Sanna E; Serra M; Mascia M P; Santoro V; Biggio G
"Ex vivo" binding of 35S-TBPS as a tool to study the pharmacology of GABAA receptors.
Advances in biochemical psychopharmacology 1990;46():89-108.
1990: Corda M G; Giorgi O; Orlandi M; Longoni B; Biggio G
Chronic administration of negative modulators produces chemical kindling and GABAA receptor down-regulation.
Advances in biochemical psychopharmacology 1990;46():153-66.
1990: Mereu G; Biggio G
Differential action of various allosteric modulators of GABAA receptor upon the spontaneous discharge rate of nigral neurons "in vivo".
Advances in biochemical psychopharmacology 1990;46():109-25.
1989: Corda M G; Giorgi O; Longoni B; Ongini E; Pesce G; Cruciani R; Biggio G
Functional coupling of GABAA receptors and benzodiazepine recognition site subtypes in the spinal cord of the rat.
European journal of pharmacology 1989;169(2-3):205-13.
1989: Sanna E; Serra M; Pepitoni S; Biggio G
Dramatic increase in nigral t-[35S]butylbicyclophosphorothionate binding sites elicited by the degeneration of the striato-nigral GABAergic pathway: reversal by diazepam.
Brain research 1989;501(1):144-9.
1989: Giorgi O; Corda M G; Gritti I; Mariotti M; Ongini E; Biggio G
Binding sites for [3H]2-oxo-quazepam in the brain of the cat: evidence for heterogeneity of benzodiazepine recognition sites.
Neuropharmacology 1989;28(7):715-8.
1989: Serra M; Sanna E; Biggio G
Isoniazid, an inhibitor of GABAergic transmission, enhances [35S]TBPS binding in rat cerebral cortex.
European journal of pharmacology 1989;164(2):385-8.
1989: Corda M G; Longoni B; Cau A; Paci S; Salvadori S; Laudani U; Biggio G
Distribution and pharmacological properties of the GABAA/benzodiazepine/chloride ionophore receptor complex in the brain of the fish Anguilla anguilla.
Journal of neurochemistry 1989;52(4):1025-34.
1989: Giorgi O; Corda M G; Fernandez A; Biggio G
The beta-carboline derivatives ZK 93426 and FG 7142 fail to precipitate abstinence signs in diazepam-dependent cats.
Pharmacology, biochemistry, and behavior 1989;32(3):671-5.
1989: Biggio G; Concas A; Corda M G; Serra M
Enhancement of GABAergic transmission by zolpidem, an imidazopyridine with preferential affinity for type I benzodiazepine receptors.
European journal of pharmacology 1989;161(2-3):173-80.
1989: Corda M G; Giorgi O; Longoni B; Biggio G
Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat.
European journal of pharmacology 1989;159(3):233-9.
1988: Pepitoni S; Porceddu M L; Toffano G; Biggio G
3H-SCH 23390 binding in the rat retina: effect of aging and environmental lighting.
Pharmacological research communications 1988;20(12):1123-4.
1988: Concas A; Serra M; Atsoggiu T; Biggio G
Foot-shock stress and anxiogenic beta-carbolines increase t-[35S]butylbicyclophosphorothionate binding in the rat cerebral cortex, an effect opposite to anxiolytics and gamma-aminobutyric acid mimetics.
Journal of neurochemistry 1988;51(6):1868-76.
1988: Longoni B; Corda M G; Biggio G
Functional interaction between GABA receptors and type I benzodiazepine recognition sites in the spinal cord of the rat.
Pharmacological research communications 1988;20(12):1089-90.
1988: Giorgi O; Corda M G; Biggio G
Ro 15-4513, like anxiogenic beta-carbolines, increases dopamine metabolism in the prefrontal cortex of the rat.
European journal of pharmacology 1988;156(1):71-5.
1988: Giorgi O; Corda M G; Fernández A; Biggio G
The abstinence syndrome in diazepam-dependent cats is precipitated by Ro 15-1788 and Ro 15-4513 but not by the benzodiazepine receptor antagonist ZK 93426.
Neuroscience letters 1988;88(2):206-10.
1988: Corda M G; Giorgi O; Longoni B; Biggio G
Decreased sensitivity to diazepam induced by chronic administration of FG 7142.
Neuroscience letters 1988;86(2):219-24.
1988: Corda M G; Giorgi O; Longoni B; Ongini E; Barnett A; Montaldo S; Biggio G
gamma-Aminobutyric acid and pentobarbital enhance 2-[3H]oxoquazepam binding to type I benzodiazepine recognition sites in rat and human brain.
Journal of neurochemistry 1988;50(3):681-7.
1988: Corda M G; Giorgi O; Longoni B M; Ongini E; Montaldo S; Paribello F; Biggio G
Characterization of 3H-2-oxo-quazepam binding in the human brain.
Progress in neuro-psychopharmacology & biological psychiatry 1988;12(5):701-12.
1988: Concas A; Serra M; Corda M G; Biggio G
Changes of 36Cl- flux and 35S-TBPS binding induced by stress and gabaergic drugs.
Advances in biochemical psychopharmacology 1988;45():227-46.
1988: Corda M G; Giorgi O; Longoni B; Ongini E; Montaldo S; Biggio G
Preferential affinity of 3H-2-oxo-quazepam for type I benzodiazepine recognition sites in the human brain.
Life sciences 1988;42(2):189-97.
1988: Concas A; Pepitoni S; Atsoggiu T; Toffano G; Biggio G
Aging reduces the GABA-dependent 36Cl- flux in rat brain membrane vesicles.
Life sciences 1988;43(22):1761-71.
1988: Corda M G; Giorgi O; Longoni B; Fernandez A; Biggio G
Increased sensitivity to inverse agonists and decreased GABA-stimulated chloride influx induced by chronic treatment with FG 7142.
Advances in biochemical psychopharmacology 1988;45():293-306.
1987: Giorgi O; De Montis G; Porceddu M L; Mele S; Calderini G; Toffano G; Biggio G
Developmental and age-related changes in D1-dopamine receptors and dopamine content in the rat striatum.
Brain research 1987;432(2):283-90.
1987: Porceddu M L; De Montis G; Mele S; Ongini E; Biggio G
D1 dopamine receptors in the rat retina: effect of dark adaptation and chronic blockade by SCH 23390.
Brain research 1987;424(2):264-71.
1987: Corda M G; Giorgi O; Mele S; Biggio G
Enhanced sensitivity to beta-carboline inverse agonists in rats chronically treated with FG 7142.
Brain research bulletin 1987;19(3):379-85.
1987: Biggio G; Concas A; Mele S; Corda M G
Changes in GABAergic transmission induced by stress, anxiogenic and anxiolytic beta-carbolines.
Brain research bulletin 1987;19(3):301-8.
1987: Porceddu M L; Giorgi O; De Montis G; Mele S; Cocco L; Ongini E; Biggio G
6-Hydroxydopamine-induced degeneration of nigral dopamine neurons: differential effect on nigral and striatal D-1 dopamine receptors.
Life sciences 1987;41(6):697-706.
1987: Marrosu F; Marrosu G; Rachel M G; Biggio G
Paradoxical reactions elicited by diazepam in children with classic autism.
Functional neurology 1987;2(3):355-61.
1987: Corda M G; Giorgi O; Longoni B; Mereu G P; Biggio G
Enhancement of gamma-aminobutyric acid binding by the anxiolytic beta-carbolines ZK 93423 and ZK 91296.
Journal of neurochemistry 1987;48(5):1355-8.
1987: Concas A; Mele S; Biggio G
Foot shock stress decreases chloride efflux from rat brain synaptoneurosomes.
European journal of pharmacology 1987;135(3):423-7.
1986: Porceddu M L; Giorgi O; Ongini E; Mele S; Biggio G
3H-SCH 23390 binding sites in the rat substantia nigra: evidence for a presynaptic localization and innervation by dopamine.
Life sciences 1986;39(4):321-8.
1986: Corda M G; Concas A; Porceddu M L; Sanna E; Biggio G
Striato-nigral denervation increases type II benzodiazepine receptors in the substantia nigra of the rat.
Neuropharmacology 1986;25(1):59-62.
1985: Porceddu M L; Corda M G; Sanna E; Biggio G
Increase in nigral type II benzodiazepine recognition sites following striatonigral denervation.
European journal of pharmacology 1985;112(2):265-7.
1984: Montaldo S; Serra M; Concas A; Corda M G; Mele S; Biggio G
Evidence for the presence of benzodiazepine receptor subclasses in different areas of the human brain.
Neuroscience letters 1984;52(3):263-8.
1980: Biggio G; Corda M G; De Montis G; Stefanini E; Gessa G L
Kainic acid differentiates GABA receptors from benzodiazepine receptors in the rat cerebellum.
Brain research 1980;193(2):589-93.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Giovanni Biggio

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Giovanni Biggio (preview)

All Publications