FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Giovanni Biggio

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Co-author Network

Publications

TOP 3
Andrea Cappelli; Alessandra Concas; Lorenzo Di Cesare Mannelli; Carla Ghelardini; Antonio Giordani; Gianluca Giorgi; Germano Giuliani; Francesco Makovec; Marco Paolino; Patrizia Porcu; Luigi Piero Stasi; Salvatore Valenti; Salvatore Vomero; Maurizio Anzini; Giulia Bini; Giovanni Biggio
Synthesis and structure-activity relationship studies in translocator protein ligands based on a pyrazolo[3,4-b]quinoline scaffold.
Maurizio Anzini; Laura Betti; Stefano Alcaro; Carlo Braile; Andrea Cappelli; Simona Daniele; Carla Ghelardini; Gino Giannaccini; Gianluca Giorgi; Vittorio Limongelli; Antonio Lucacchini; Luciana Marinelli; Claudia Martini; Maria Paola Mascia; Ettore Novellino; Francesco Ortuso; Salvatore Valenti; Salvatore Vomero; Lorenzo Di Cesare Mannelli; Giovanni Biggio
New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds.
Maria Manconi; Carla Caddeo; Chiara Sinico; Donatella Valenti; Maria Cristina Mostallino; Giovanni Biggio; Anna Maria Fadda
Ex vivo skin delivery of diclofenac by transcutol containing liposomes and suggested mechanism of vesicle-skin interaction.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Giovanni Biggio (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Andrea Cappelli; Alessandra Concas; Lorenzo Di Cesare Mannelli; Carla Ghelardini; Antonio Giordani; Gianluca Giorgi; Germano Giuliani; Francesco Makovec; Marco Paolino; Patrizia Porcu; Luigi Piero Stasi; Salvatore Valenti; Salvatore Vomero; Maurizio Anzini; Giulia Bini; Giovanni Biggio
Synthesis and structure-activity relationship studies in translocator protein ligands based on a pyrazolo[3,4-b]quinoline scaffold.
Journal of medicinal chemistry 2011;54(20):7165-75.
2011: Maurizio Anzini; Laura Betti; Stefano Alcaro; Carlo Braile; Andrea Cappelli; Simona Daniele; Carla Ghelardini; Gino Giannaccini; Gianluca Giorgi; Vittorio Limongelli; Antonio Lucacchini; Luciana Marinelli; Claudia Martini; Maria Paola Mascia; Ettore Novellino; Francesco Ortuso; Salvatore Valenti; Salvatore Vomero; Lorenzo Di Cesare Mannelli; Giovanni Biggio
New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds.
Journal of medicinal chemistry 2011;54(16):5694-711.
2011: Maria Manconi; Carla Caddeo; Chiara Sinico; Donatella Valenti; Maria Cristina Mostallino; Giovanni Biggio; Anna Maria Fadda
Ex vivo skin delivery of diclofenac by transcutol containing liposomes and suggested mechanism of vesicle-skin interaction.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2011;78(1):27-35.
2011: Laura Dazzi; Alessandra Matzeu; Giovanni Biggio
Role of ionotropic glutamate receptors in the regulation of hippocampal norepinephrine output in vivo.
Brain research 2011;1386():41-9.
2011: Giuseppe Talani; Giovanni Biggio; Enrico Sanna
Enhanced Sensitivity to Ethanol-Induced Inhibition of LTP in CA1 Pyramidal Neurons of Socially Isolated C57BL/6J Mice: Role of Neurosteroids.
Frontiers in endocrinology 2011;2():56.
2011: Enrico Sanna; Giuseppe Talani; Nicola Obili; Maria Paola Mascia; Maria Cristina Mostallino; Pietro Paolo Secci; Maria Giuseppina Pisu; Francesca Biggio; Cinzia Utzeri; Pierluigi Olla; Giovanni Biggio; Paolo Follesa
Voluntary Ethanol Consumption Induced by Social Isolation Reverses the Increase of α(4)/δ GABA(A) Receptor Gene Expression and Function in the Hippocampus of C57BL/6J Mice.
Frontiers in neuroscience 2011;5():15.
2010: Andrea Cappelli; Salvatore Valenti; Alessandra Mancini; Germano Giuliani; Maurizio Anzini; Saverio Altieri; Silva Bortolussi; Cinzia Ferrari; Anna Maria Clerici; Cecilia Zonta; Fabio Carraro; Irene Filippi; Gianluca Giorgi; Alessandro Donati; Sandra Ristori; Salvatore Vomero; Alessandra Concas; Giovanni Biggio
Carborane-conjugated 2-quinolinecarboxamide ligands of the translocator protein for boron neutron capture therapy.
Bioconjugate chemistry 2010;21(12):2213-21.
2010: Stefano Cabras; Francesca Saba; Camilla Reali; Maria Laura Scorciapino; Annarita Sirigu; Giuseppe Talani; Giovanni Biggio; Valeria Sogos
Antidepressant imipramine induces human astrocytes to differentiate into cells with neuronal phenotype.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2010;13(5):603-15.
2010: Arianna Calza; Cristiana Sogliano; Francesca Santoru; Carla Marra; Maria Maddalena Angioni; Maria Cristina Mostallino; Giovanni Biggio; Alessandra Concas
Neonatal exposure to estradiol in rats influences neuroactive steroid concentrations, GABAA receptor expression, and behavioral sensitivity to anxiolytic drugs.
Journal of neurochemistry 2010;113(5):1285-95.
2010: Melinda L Morgan; Andrea J Rapkin; Giovanni Biggio; Mariangela Serra; Maria Giuseppina Pisu; Natalie Rasgon
Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women.
Archives of women's mental health 2010;13(1):91-8.
2009: Enrico Sanna; Maria Cristina Mostallino; Luca Murru; Mario Carta; Giuseppe Talani; Stefano Zucca; Maria Luisa Mura; Elisabetta Maciocco; Giovanni Biggio
Changes in expression and function of extrasynaptic GABAA receptors in the rat hippocampus during pregnancy and after delivery.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(6):1755-65.
2009: Giovanni Biggio; Maria Cristina Mostallino; Paolo Follesa; Alessandra Concas; Enrico Sanna
GABA(A) receptor function and gene expression during pregnancy and postpartum.
International review of neurobiology 2009;85():73-94.
2008: Antonella Tuveri; Anna Maria Paoletti; Marisa Orrù; Gian Benedetto B Melis; Maria Francesca Marotto; Pierina Zedda; Francesco Marrosu; Cristiana Sogliano; Carla Marra; Giovanni Biggio; Alessandra Concas
Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy.
Epilepsia 2008;49(7):1221-9.
2008: Mario Carta; Luca Murru; E Barabino; Giuseppe Talani; Enrico Sanna; Giovanni Biggio
Isoniazid-induced reduction in GABAergic neurotransmission alters the function of the cerebellar cortical circuit.
Neuroscience 2008;154(2):710-9.
2008: Katsuhiko Sekimata; Kentaro Hatano; Mikako Ogawa; Junichiro Abe; Yasuhiro Magata; Giovanni Biggio; Mariangela Serra; Valentino Laquintana; Nunzio Denora; Andrea Latrofa; Giuseppe Trapani; Gaetano Liso; Kengo Ito
Radiosynthesis and in vivo evaluation of N-[11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors.
Nuclear medicine and biology 2008;35(3):327-34.
2008: Andrea Cappelli; Germano Giuliani; Salvatore Valenti; Maurizio Anzini; Salvatore Vomero; Gianluca Giorgi; Cristiana Sogliano; Elisabetta Maciocco; Giovanni Biggio; Alessandra Concas
Synthesis and structure-activity relationship studies in peripheral benzodiazepine receptor ligands related to alpidem.
Bioorganic & medicinal chemistry 2008;16(6):3428-37.
2008: Mariangela Serra; Maria Giuseppina Pisu; Maria Cristina Mostallino; Enrico Sanna; Giovanni Biggio
Changes in neuroactive steroid content during social isolation stress modulate GABAA receptor plasticity and function.
Brain research reviews 2008;57(2):520-30.
2008: Carola Eva; Paolo Mele; Devis Collura; Antonella Nai; Maria Giuseppina Pisu; Mariangela Serra; Giovanni Biggio
Modulation of neuropeptide Y and Y1 receptor expression in the amygdala by fluctuations in the brain content of neuroactive steroids during ethanol drinking discontinuation in Y1R/LacZ transgenic mice.
Journal of neurochemistry 2008;104(4):1043-54.
2007: Paolo Follesa; Francesca Biggio; Giorgio Gorini; Stefania Caria; Giuseppe Talani; Laura Dazzi; Monica Puligheddu; Francesco Marrosu; Giovanni Biggio
Vagus nerve stimulation increases norepinephrine concentration and the gene expression of BDNF and bFGF in the rat brain.
Brain research 2007;1179():28-34.
2007: Giovanni Biggio; Alessandra Concas; Paolo Follesa; Enrico Sanna; Mariangela Serra
Stress, ethanol, and neuroactive steroids.
Pharmacology & therapeutics 2007;116(1):140-71.
2007: Valentino Laquintana; Nunzio Denora; Angela Lopedota; Hiromi Suzuki; Makoto Sawada; Mariangela Serra; Giovanni Biggio; Andrea Latrofa; Giuseppe Trapani; Gaetano Liso
N-benzyl-2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(6-(7-nitrobenzo[c][1,2,5]oxadiazol-4-ylamino)hexyl)acetamide as a new fluorescent probe for peripheral benzodiazepine receptor and microglial cell visualization.
Bioconjugate chemistry 2007;18(5):1397-407.
2007: Nunzio Denora; Valentino Laquintana; Angela Lopedota; Mariangela Serra; Laura Dazzi; Giovanni Biggio; Dhananjay Pal; Laura jane Jolliffe; Andrea Latrofa; Giuseppe Trapani; Gaetano Liso
Novel L-Dopa and dopamine prodrugs containing a 2-phenyl-imidazopyridine moiety.
Pharmaceutical research 2007;24(7):1309-24.
2007: Laura Dazzi; Emanuele Seu; Giulia Cherchi; Pier Paolo Barbieri; Alessandra Matzeu; Giovanni Biggio
Estrous cycle-dependent changes in basal and ethanol-induced activity of cortical dopaminergic neurons in the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(4):892-901.
2007: Maria Paola Mascia; Elisabetta Bachis; Nicola Obili; Elisabetta Maciocco; Giovanni Antonio Cocco; GianPietro Sechi; Giovanni Biggio
Thiocolchicoside inhibits the activity of various subtypes of recombinant GABA(A) receptors expressed in Xenopus laevis oocytes.
European journal of pharmacology 2007;558(1-3):37-42.
2007: Mariangela Serra; Enrico Sanna; Maria Cristina Mostallino; Giovanni Biggio
Social isolation stress and neuroactive steroids.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2007;17(1):1-11.
2006: Maria Cristina Mostallino; Maria Luisa Mura; Elisabetta Maciocco; Luca Murru; Enrico Sanna; Giovanni Biggio
Changes in expression of the delta subunit of the GABA (A) receptor and in receptor function induced by progesterone exposure and withdrawal.
Journal of neurochemistry 2006;99(1):321-32.
2006: Maria Giuseppina Pisu; Ivan Floris; Elisabetta Maciocco; Mariangela Serra; Giovanni Biggio
Anticipation and consumption of food each increase the concentration of neuroactive steroids in rat brain and plasma.
Pharmacology, biochemistry, and behavior 2006;85(1):76-81.
2006: Mario Carta; Luca Murru; Paolo Botta; Giuseppe Talani; GianPietro Sechi; Pierluigi De Riu; Enrico Sanna; Giovanni Biggio
The muscle relaxant thiocolchicoside is an antagonist of GABAA receptor function in the central nervous system.
Neuropharmacology 2006;51(4):805-15.
2006: maria carolina hardoy; Mariangela Serra; Mauro Giovanni Carta; Paolo Contu; Maria Giuseppina Pisu; Giovanni Biggio
Increased neuroactive steroid concentrations in women with bipolar disorder or major depressive disorder.
Journal of clinical psychopharmacology 2006;26(4):379-84.
2006: Andrea J Rapkin; Giovanni Biggio; Alessandra Concas
Oral contraceptives and neuroactive steroids.
Pharmacology, biochemistry, and behavior 2006;84(4):628-34.
2006: Carola Eva; Alessandra Oberto; Paolo Mele; Mariangela Serra; Giovanni Biggio
Role of brain neuroactive steroids in the functional interplay between the GABA(A) and the NPY-Y1 receptor mediated signals in the amygdala.
Pharmacology, biochemistry, and behavior 2006;84(4):568-80.
2006: Rita Pillai; Franca Scintu; Laura Scorciapino; Mario Carta; Luca Murru; Giovanni Biggio; Stefano Cabras; Camilla Reali; Valeria Sogos
Human astrocytes can be induced to differentiate into cells with neuronal phenotype.
Experimental cell research 2006;312(12):2336-46.
2006: Mariangela Serra; Maria Cristina Mostallino; Giuseppe Talani; Maria Giuseppina Pisu; Mario Carta; Maria Luisa Mura; Ivan Floris; Elisabetta Maciocco; Enrico Sanna; Giovanni Biggio
Social isolation-induced increase in alpha and delta subunit gene expression is associated with a greater efficacy of ethanol on steroidogenesis and GABA receptor function.
Journal of neurochemistry 2006;98(1):122-33.
2006: Paolo Follesa; Francesca Biggio; Giuseppe Talani; Luca Murru; Mariangela Serra; Enrico Sanna; Giovanni Biggio
Neurosteroids, GABAA receptors, and ethanol dependence.
Psychopharmacology 2006;186(3):267-80.
2006: Alessandra Concas; Cristiana Sogliano; Patrizia Porcu; Carla Marra; Andrea Brundu; Giovanni Biggio
Neurosteroids in nicotine and morphine dependence.
Psychopharmacology 2006;186(3):281-92.
2006: Andrea J Rapkin; Melinda Morgan; Cristiana Sogliano; Giovanni Biggio; Alessandra Concas
Decreased neuroactive steroids induced by combined oral contraceptive pills are not associated with mood changes.
Fertility and sterility 2006;85(5):1371-8.
2006: Anna Maria Paoletti; Sandra Romagnino; Rossana Contu; Marisa Orrù; Maria Francesca Marotto; Pierina Zedda; Stefano Lello; Giovanni Biggio; Alessandra Concas; Gian Benedetto Melis
Observational study on the stability of the psychological status during normal pregnancy and increased blood levels of neuroactive steroids with GABA-A receptor agonist activity.
Psychoneuroendocrinology 2006;31(4):485-92.
2005: Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Giovanni Biggio
Social isolation-induced changes in the hypothalamic-pituitary-adrenal axis in the rat.
Stress (Amsterdam, Netherlands) 2005;8(4):259-64.
2005: Enrico Sanna; Fabio Busonero; Giuseppe Talani; Maria Cristina Mostallino; Maria Luisa Mura; Maria Giuseppina Pisu; Elisabetta Maciocco; Mariangela Serra; Giovanni Biggio
Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates.
European journal of pharmacology 2005;519(1-2):31-42.
2005: Francesco Marrosu; F Santoni; Monica Puligheddu; Luigi Barberini; Alberto Maleci; F Ennas; MM Mascia; G Zanetti; Antonella Tuveri; Giovanni Biggio
Increase in 20-50 Hz (gamma frequencies) power spectrum and synchronization after chronic vagal nerve stimulation.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2005;116(9):2026-36.
2005: Paolo Follesa; Maria Cristina Mostallino; Francesca Biggio; Giorgio Gorini; Stefania Caria; Fabio Busonero; Luca Murru; Maria Luisa Mura; Enrico Sanna; Giovanni Biggio
Distinct patterns of expression and regulation of GABA receptors containing the delta subunit in cerebellar granule and hippocampal neurons.
Journal of neurochemistry 2005;94(3):659-71.
2005: Maria Paola Mascia; Battistina Asproni; Fabio Busonero; Giuseppe Talani; Elisabetta Maciocco; Amedeo Pau; Riccardo Cerri; Enrico Sanna; Giovanni Biggio
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
European journal of pharmacology 2005;516(3):204-11.
2005: Maria Grazia Ferlin; Gianfranco Chiarelotto; Stefano Dall'Acqua; Elisabetta Maciocco; Maria Paola Mascia; Maria Giuseppina Pisu; Giovanni Biggio
Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity.
Bioorganic & medicinal chemistry 2005;13(10):3531-41.
2005: Laura Dazzi; Emanuele Seu; Giulia Cherchi; Giovanni Biggio
Chronic administration of the SSRI fluvoxamine markedly and selectively reduces the sensitivity of cortical serotonergic neurons to footshock stress.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2005;15(3):283-90.
2005: Battistina Asproni; Giuseppe Talani; Fabio Busonero; Amedeo Pau; Sebastiano Sanna; Riccardo Cerri; Maria Paola Mascia; Enrico Sanna; Giovanni Biggio
Synthesis, structure-activity relationships at the GABA(A) receptor in rat brain, and differential electrophysiological profile at the recombinant human GABA(A) receptor of a series of substituted 1,2-diphenylimidazoles.
Journal of medicinal chemistry 2005;48(7):2638-45.
2005: Giuseppe Trapani; Valentino Laquintana; Nunzio Denora; Adriana Trapani; Angela Lopedota; Andrea Latrofa; Massimo Franco; Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Enrico Sanna; Giovanni Biggio; Gaetano Liso
Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands.
Journal of medicinal chemistry 2005;48(1):292-305.
2004: Paolo Follesa; Francesca Biggio; Stefania Caria; Giorgio Gorini; Giovanni Biggio
Modulation of GABA(A) receptor gene expression by allopregnanolone and ethanol.
European journal of pharmacology 2004;500(1-3):413-25.
2004: Enrico Sanna; Giuseppe Talani; Fabio Busonero; Maria Giuseppina Pisu; Robert H Purdy; Mariangela Serra; Giovanni Biggio
Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(29):6521-30.
2004: Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Stefano Floris; Emanuela Cannas; Alessandra Mossa; Giuseppe Trapani; Andrea Latrofa; Robert H Purdy; Giovanni Biggio
Social isolation increases the response of peripheral benzodiazepine receptors in the rat.
Neurochemistry international 2004;45(1):141-8.
2004: Maria Cristina Mostallino; Maria Paola Mascia; Maria Giuseppina Pisu; Fabio Busonero; Giuseppe Talani; Giovanni Biggio
Inhibition by miltirone of up-regulation of GABAA receptor alpha4 subunit mRNA by ethanol withdrawal in hippocampal neurons.
European journal of pharmacology 2004;494(2-3):83-90.
2004: Patrizia Porcu; Cristiana Sogliano; Cristina Ibba; Massimo Piredda; Silvia Tocco; Carla Marra; Robert H Purdy; Giovanni Biggio; Alessandra Concas
Failure of gamma-hydroxybutyric acid both to increase neuroactive steroid concentrations in adrenalectomized-orchiectomized rats and to induce tolerance to its steroidogenic effect in intact animals.
Brain research 2004;1012(1-2):160-8.
2004: Paolo Mele; Alessandra Oberto; Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Giovanni Biggio; Carola Eva
Increased expression of the gene for the Y1 receptor of neuropeptide Y in the amygdala and paraventricular nucleus of Y1R/LacZ transgenic mice in response to restraint stress.
Journal of neurochemistry 2004;89(6):1471-8.
2004: Anna Maria Paoletti; Stefano Lello; Stefania Fratta; Marisa Orrù; Francesca Ranuzzi; Cristiana Sogliano; Alessandra Concas; Giovanni Biggio; Gian Benedetto Melis
Psychological effect of the oral contraceptive formulation containing 3 mg of drospirenone plus 30 microg of ethinyl estradiol.
Fertility and sterility 2004;81(3):645-51.
2004: Laura Dazzi; Emanuele Seu; Giulia Cherchi; Giovanni Biggio
Inhibition of stress-induced dopamine output in the rat prefrontal cortex by chronic treatment with olanzapine.
Biological psychiatry 2004;55(5):477-83.
2004: Paolo Follesa; Francesca Biggio; Luisa Mancuso; Stefano Cabras; Stefania Caria; Giorgio Gorini; Annalisa Manca; Alessandro Orru; Giovanni Biggio
Ethanol withdrawal-induced up-regulation of the alpha2 subunit of the GABAA receptor and its prevention by diazepam or gamma-hydroxybutyric acid.
Brain research. Molecular brain research 2004;120(2):130-7.
2004: Giuseppe Trapani; Annalisa Cutrignelli; Andrea Latrofa; Massimo Franco; Mariangela Serra; Maria Giuseppina Pisu; Giovanni Biggio; Gaetano Liso
Valproic acid-hydrophilic cyclodextrin complexes and valproic acid-solid dispersions: evaluation of their potential pharmaceutical use.
Drug development and industrial pharmacy 2004;30(1):53-64.
2003: Enrico Sanna; Maria Cristina Mostallino; Fabio Busonero; Giuseppe Talani; Stefania Tranquilli; Manuel Mameli; Saturnino Spiga; Paolo Follesa; Giovanni Biggio
Changes in GABA(A) receptor gene expression associated with selective alterations in receptor function and pharmacology after ethanol withdrawal.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(37):11711-24.
2003: Giovanni Biggio; Laura Dazzi; Francesca Biggio; Luisa Mancuso; Giuseppe Talani; Fabio Busonero; Maria Cristina Mostallino; Enrico Sanna; Paolo Follesa
Molecular mechanisms of tolerance to and withdrawal of GABA(A) receptor modulators.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(6):411-23.
2003: Angelo Carotti; Cosimo Altomare; Luisa Savini; Luisa Chiasserini; Cesare Pellerano; Maria Paola Mascia; Elisabetta Maciocco; Fabio Busonero; Manuel Mameli; Giovanni Biggio; Enrico Sanna
High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones.
Bioorganic & medicinal chemistry 2003;11(23):5259-72.
2003: Cosimo Altomare; Giuseppe Trapani; Andrea Latrofa; Mariangela Serra; Enrico Sanna; Giovanni Biggio; Gaetano Liso
Highly water-soluble derivatives of the anesthetic agent propofol: in vitro and in vivo evaluation of cyclic amino acid esters.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;20(1):17-26.
2003: Laura Dazzi; Emanuele Seu; Giulia Cherchi; Giovanni Biggio
Antagonism of the stress-induced increase in cortical norepinephrine output by the selective norepinephrine reuptake inhibitor reboxetine.
European journal of pharmacology 2003;476(1-2):55-61.
2003: Andrea Cappelli; Gal la Pericot Mohr; Andrea Gallelli; Germano Giuliani; Maurizio Anzini; Salvatore Vomero; Massimo Fresta; Patrizia Porcu; Elisabetta Maciocco; Alessandra Concas; Giovanni Biggio; Alessandro Donati
Structure-activity relationships in carboxamide derivatives based on the targeted delivery of radionuclides and boron atoms by means of peripheral benzodiazepine receptor ligands.
Journal of medicinal chemistry 2003;46(17):3568-71.
2003: Giuseppe Trapani; Valentino Laquintana; Andrea Latrofa; Jianguo Ma; Karin Reed; Mariangela Serra; Giovanni Biggio; Gaetano Liso; James M Gallo
Peripheral benzodiazepine receptor ligand-melphalan conjugates for potential selective drug delivery to brain tumors.
Bioconjugate chemistry 2003;14(4):830-9.
2003: Francesco Marrosu; Alessandra Serra; Alberto Maleci; Monica Puligheddu; Giovanni Biggio; Mario Piga
Correlation between GABA(A) receptor density and vagus nerve stimulation in individuals with drug-resistant partial epilepsy.
Epilepsy research 2003;55(1-2):59-70.
2003: Paolo Follesa; Luisa Mancuso; Francesca Biggio; Maria Cristina Mostallino; Annalisa Manca; Maria Paola Mascia; Fabio Busonero; Giuseppe Talani; Enrico Sanna; Giovanni Biggio
Gamma-hydroxybutyric acid and diazepam antagonize a rapid increase in GABA(A) receptors alpha(4) subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells.
Molecular pharmacology 2003;63(4):896-907.
2003: Mariangela Serra; Maria Giuseppina Pisu; Ivan Floris; Valeria Cara; Robert H Purdy; Giovanni Biggio
Social isolation-induced increase in the sensitivity of rats to the steroidogenic effect of ethanol.
Journal of neurochemistry 2003;85(1):257-63.
2003: Giuseppe Trapani; Andrea Latrofa; Massimo Franco; Antonio Carrieri; Saverio Cellamare; Mariangela Serra; Enrico Sanna; Giovanni Biggio; Gaetano Liso
Alpidem analogues containing a GABA or glycine moiety as new anticonvulsant agents.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;18(3-4):231-40.
2003: Patrizia Porcu; Cristiana Sogliano; Monica Cinus; Robert H Purdy; Giovanni Biggio; Alessandra Concas
Nicotine-induced changes in cerebrocortical neuroactive steroids and plasma corticosterone concentrations in the rat.
Pharmacology, biochemistry, and behavior 2003;74(3):683-90.
2003: Maneesh Gupta; Boris M Hogema; Markus Grompe; Teodoro Bottiglieri; Alessandra Concas; Giovanni Biggio; Cristiana Sogliano; Antonello E Rigamonti; Phillip L Pearl; O Carter Snead; Cornelis Jakobs; K Michael Gibson
Murine succinate semialdehyde dehydrogenase deficiency.
Annals of neurology 2003;54 Suppl 6():S81-90.
2002: Maria Paola Mascia; Francesca Biggio; Luisa Mancuso; Stefano Cabras; Pier Luigi Cocco; Giorgio Gorini; Annalisa Manca; Carla Marra; Robert H Purdy; Paolo Follesa; Giovanni Biggio
Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, ganaxolone in cultured rat cerebellar granule cells.
The Journal of pharmacology and experimental therapeutics 2002;303(3):1014-20.
2002: Laura Dazzi; Mariangela Serra; Emanuele Seu; Giulia Cherchi; Maria Giuseppina Pisu; Robert H Purdy; Giovanni Biggio
Progesterone enhances ethanol-induced modulation of mesocortical dopamine neurons: antagonism by finasteride.
Journal of neurochemistry 2002;83(5):1103-9.
2002: Battistina Asproni; Amedeo Pau; Mauro Bitti; Marilena Melosu; Riccardo Cerri; Laura Dazzi; Emanuele Seu; Elisabetta Maciocco; Enrico Sanna; Fabio Busonero; Giuseppe Talani; Luca Pusceddu; Cosimo Altomare; Giuseppe Trapani; Giovanni Biggio
Synthesis and pharmacological evaluation of 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-phenylpiperazines with clozapine-like mixed activities at dopamine D(2), serotonin, and GABA(A) receptors.
Journal of medicinal chemistry 2002;45(21):4655-68.
2002: Enrico Sanna; Fabio Busonero; Giuseppe Talani; Mario Carta; Federico Massa; Michela Peis; Elisabetta Maciocco; Giovanni Biggio
Comparison of the effects of zaleplon, zolpidem, and triazolam at various GABA(A) receptor subtypes.
European journal of pharmacology 2002;451(2):103-10.
2002: Alessandra Oberto; Mariangela Serra; Maria Giuseppina Pisu; Giovanni Biggio; Carola Eva
Changes in expression of the neuropeptide Y Y1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery.
Journal of neurochemistry 2002;82(5):1272-81.
2002: Mariangela Serra; M Giuseppina Pisul; Laura Dazzi; Robert H Purdy; Giovanni Biggio
Prevention of the stress-induced increase in the concentration of neuroactive steroids in rat brain by long-term administration of mirtazapine but not of fluoxetine.
Journal of psychopharmacology (Oxford, England) 2002;16(2):133-8.
2002: Laura Dazzi; Vincenzo Vignone; Emanuele Seu; Stefania Ladu; Giovanni Vacca; Giovanni Biggio
Inhibition by venlafaxine of the increase in norepinephrine output in rat prefrontal cortex elicited by acute stress or by the anxiogenic drug FG 7142.
Journal of psychopharmacology (Oxford, England) 2002;16(2):125-31.
2002: Laura Dazzi; Mariangela Serra; Giovanni Vacca; Stefania Ladu; Andrea Latrofa; Giuseppe Trapani; Giovanni Biggio
Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output.
Brain research 2002;932(1-2):135-9.
2002: Giuseppe Trapani; Laura Dazzi; Maria Giuseppina Pisu; Antonia Reho; Emanuele Seu; Giovanni Biggio
A rapid method for obtaining finasteride, a 5alpha-reductase inhibitor, from commercial tablets.
Brain research. Brain research protocols 2002;9(2):130-4.
2002: Paolo Follesa; Patrizia Porcu; Cristiana Sogliano; M Cinus; Francesca Biggio; Luisa Mancuso; Maria Cristina Mostallino; Anna Maria Paoletti; Robert H Purdy; Giovanni Biggio; Alessandra Concas
Changes in GABAA receptor gamma 2 subunit gene expression induced by long-term administration of oral contraceptives in rats.
Neuropharmacology 2002;42(3):325-36.
2002: Paolo Follesa; Luisa Mancuso; Francesca Biggio; E Cagetti; Massimo Franco; Giuseppe Trapani; Giovanni Biggio
Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, zaleplon or zolpidem.
Neuropharmacology 2002;42(2):191-8.
2002: Laura Dazzi; Stefania Ladu; Francesca Spiga; Giovanni Vacca; Antonella Rivano; Luigi Pira; Giovanni Biggio
Chronic treatment with imipramine or mirtazapine antagonizes stress- and FG7142-induced increase in cortical norepinephrine output in freely moving rats.
Synapse (New York, N.Y.) 2002;43(1):70-7.
2001: Maria Giuseppina Pisu; G Papi; Patrizia Porcu; Giuseppe Trapani; Andrea Latrofa; Giovanni Biggio; Mariangela Serra
Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes.
European journal of pharmacology 2001;432(2-3):129-34.
2001: Paola Pierobon; Rosario Minei; Patrizia Porcu; Cristiana Sogliano; Angela Tino; Giuseppe Marino; Giovanni Biggio; Alessandra Concas
Putative glycine receptors in Hydra: a biochemical and behavioural study.
The European journal of neuroscience 2001;14(10):1659-66.
2001: Paolo Follesa; Alessandra Concas; Patrizia Porcu; Enrico Sanna; Mariangela Serra; Maria Cristina Mostallino; Robert H Purdy; Giovanni Biggio
Role of allopregnanolone in regulation of GABA(A) receptor plasticity during long-term exposure to and withdrawal from progesterone.
Brain research. Brain research reviews 2001;37(1-3):81-90.
2001: Mariangela Serra; Maria Giuseppina Pisu; M Muggironi; V Parodo; G Papi; R Sari; Laura Dazzi; Francesca Spiga; Robert H Purdy; Giovanni Biggio
Opposite effects of short- versus long-term administration of fluoxetine on the concentrations of neuroactive steroids in rat plasma and brain.
Psychopharmacology 2001;158(1):48-54.
2001: G Ferrara; Mariangela Serra; Francesca Zammaretti; Maria Giuseppina Pisu; GianCarlo Panzica; Giovanni Biggio; Carola Eva
Increased expression of the neuropeptide Y receptor Y(1) gene in the medial amygdala of transgenic mice induced by long-term treatment with progesterone or allopregnanolone.
Journal of neurochemistry 2001;79(2):417-25.
2001: Laura Dazzi; Mariangela Serra; Francesca Spiga; Maria Giuseppina Pisu; J David Jentsch; Giovanni Biggio
Prevention of the stress-induced increase in frontal cortical dopamine efflux of freely moving rats by long-term treatment with antidepressant drugs.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2001;11(5):343-9.
2001: Maria Luisa Barbaccia; D Affricano; Robert H Purdy; E Maciocco; Francesca Spiga; Giovanni Biggio
Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(4):489-97.
2001: Massimo Franco; Giuseppe Trapani; Andrea Latrofa; C Tullio; M R Provenzano; Mariangela Serra; M Muggironi; Giovanni Biggio; Gaetano Liso
Dissolution properties and anticonvulsant activity of phenytoin-polyethylene glycol 6000 and -polyvinylpyrrolidone K-30 solid dispersions.
International journal of pharmaceutics 2001;225(1-2):63-73.
2001: Paolo Follesa; E Cagetti; Luisa Mancuso; Francesca Biggio; Annalisa Manca; Elisabetta Maciocco; Federico Massa; M S Desole; Mario Carta; Fabio Busonero; Enrico Sanna; Giovanni Biggio
Increase in expression of the GABA(A) receptor alpha(4) subunit gene induced by withdrawal of, but not by long-term treatment with, benzodiazepine full or partial agonists.
Brain research. Molecular brain research 2001;92(1-2):138-48.
2001: Laura Dazzi; Giovanni Vacca; Stefania Ladu; Maria Giuseppina Pisu; Mariangela Serra; Giovanni Biggio
Long-term treatment with antidepressant drugs reduces the sensitivity of cortical cholinergic neurons to the activating actions of stress and the anxiogenic drug FG 7142.
Neuropharmacology 2001;41(2):229-37.
2001: Natalie Rasgon; M Serra; Giovanni Biggio; M G Pisu; Lynn Fairbanks; S Tanavoli; Andrea J Rapkin
Neuroactive steroid-serotonergic interaction: responses to an intravenous L-tryptophan challenge in women with premenstrual syndrome.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(1):25-33.
2001: Luisa Savini; Luisa Chiasserini; Cesare Pellerano; Giovanni Biggio; Elisabetta Maciocco; Mariangela Serra; N Cinone; Antonio Carrieri; Cosimo Altomare; Angelo Carotti
High affinity central benzodiazepine receptor ligands. Part 2: quantitative structure-activity relationships and comparative molecular field analysis of pyrazolo[4,3-c]quinolin-3-ones.
Bioorganic & medicinal chemistry 2001;9(2):431-44.
2001: Laura Dazzi; Francesca Spiga; Luigi Pira; Stefania Ladu; Giovanni Vacca; A Rivano; J David Jentsch; Giovanni Biggio
Inhibition of stress- or anxiogenic-drug-induced increases in dopamine release in the rat prefrontal cortex by long-term treatment with antidepressant drugs.
Journal of neurochemistry 2001;76(4):1212-20.
2001: Maria Luisa Barbaccia; Mariangela Serra; Robert H Purdy; Giovanni Biggio
Stress and neuroactive steroids.
International review of neurobiology 2001;46():243-72.
2001: Giovanni Biggio; Paolo Follesa; Enrico Sanna; Robert H Purdy; Alessandra Concas
GABAA-receptor plasticity during long-term exposure to and withdrawal from progesterone.
International review of neurobiology 2001;46():207-41.
2000: Paolo Follesa; E Cagetti; S Porta; G Espositoto; Giovanni Biggio
Pivagabine-induced increases in the abundance of CRF mRNA in the cerebral cortex and hypothalamus of rats.
Brain research. Molecular brain research 2000;84(1-2):52-7.
2000: Mariangela Serra; M Littera; Maria Giuseppina Pisu; M Muggironi; Robert H Purdy; Giovanni Biggio
Steroidogenesis in rat brain induced by short- and long-term administration of carbamazepine.
Neuropharmacology 2000;39(12):2448-56.
2000: Mariangela Serra; Maria Giuseppina Pisu; M Littera; G Papi; Enrico Sanna; Federica Tuveri; L Usala; Robert H Purdy; Giovanni Biggio
Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain.
Journal of neurochemistry 2000;75(2):732-40.
2000: Paolo Follesa; Mariangela Serra; E Cagetti; Maria Giuseppina Pisu; S Porta; Stefano Floris; Federico Massa; Enrico Sanna; Giovanni Biggio
Allopregnanolone synthesis in cerebellar granule cells: roles in regulation of GABA(A) receptor expression and function during progesterone treatment and withdrawal.
Molecular pharmacology 2000;57(6):1262-70.
2000: Alessandra Concas; Patrizia Porcu; Cristiana Sogliano; Mariangela Serra; Robert H Purdy; Giovanni Biggio
Caffeine-induced increases in the brain and plasma concentrations of neuroactive steroids in the rat.
Pharmacology, biochemistry, and behavior 2000;66(1):39-45.
2000: Giuseppe Trapani; Cosimo Altomare; Gaetano Liso; Enrico Sanna; Giovanni Biggio
Propofol in anesthesia. Mechanism of action, structure-activity relationships, and drug delivery.
Current medicinal chemistry 2000;7(2):249-71.
1999: Giuseppe Trapani; Massimo Franco; Andrea Latrofa; L Ricciardi; A Carotti; Mariangela Serra; Enrico Sanna; Giovanni Biggio; Gaetano Liso
Novel 2-phenylimidazo[1,2-a]pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies.
Journal of medicinal chemistry 1999;42(19):3934-41.
1999: Mariangela Serra; Laura Dazzi; M Caddeo; Costantino Floris; Giovanni Biggio
Reversal by flunarizine of the decrease in hippocampal acetylcholine release in pentylenetetrazole-kindled rats.
Biochemical pharmacology 1999;58(1):145-9.
1999: Alessandra Concas; Paolo Follesa; Maria Luisa Barbaccia; Robert H Purdy; Giovanni Biggio
Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites.
European journal of pharmacology 1999;375(1-3):225-35.
1999: Paolo Follesa; A Tarantino; Stefano Floris; A Mallei; S Porta; G Tuligi; E Cagetti; M Caddeo; A Mura; Mariangela Serra; Giovanni Biggio
Changes in the gene expression of GABAA receptor subunit mRNAs in the septum of rats subjected to pentylenetetrazol-induced kindling.
Brain research. Molecular brain research 1999;70(1):1-8.
1999: Mariangela Serra; P Madau; M F Chessa; M Caddeo; Enrico Sanna; Giuseppe Trapani; M Franco; Gaetano Liso; Robert H Purdy; Maria Luisa Barbaccia; Giovanni Biggio
2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats.
British journal of pharmacology 1999;127(1):177-87.
1999: Mariangela Serra; Alessandra Concas; Maria Cristina Mostallino; M F Chessa; Massimo Stomati; Felice Petraglia; A R Genazzani; Giovanni Biggio
Antagonism by pivagabine of stress-induced changes in GABAA receptor function and corticotropin-releasing factor concentrations in rat brain.
Psychoneuroendocrinology 1999;24(3):269-84.
1999: Enrico Sanna; Costantino Motzo; M Usala; Mariangela Serra; Laura Dazzi; Elisabetta Maciocco; Giuseppe Trapani; Andrea Latrofa; Gaetano Liso; Giovanni Biggio
Characterization of the electrophysiological and pharmacological effects of 4-iodo-2,6-diisopropylphenol, a propofol analogue devoid of sedative-anaesthetic properties.
British journal of pharmacology 1999;126(6):1444-54.
1999: Enrico Sanna; D Pau; Federica Tuveri; Federico Massa; Elisabetta Maciocco; C Acquas; Costantino Floris; S N Fontana; G Maira; Giovanni Biggio
Molecular and neurochemical evaluation of the effects of etizolam on GABAA receptors under normal and stress conditions.
Arzneimittel-Forschung 1999;49(2):88-95.
1999: Paolo Follesa; A Mallei; Stefano Floris; Maria Cristina Mostallino; Enrico Sanna; Giovanni Biggio
Increased abundance of GABAA receptor subunit mRNAs in the brain of Long-Evans Cinnamon rats, an animal model of Wilson's disease.
Brain research. Molecular brain research 1999;63(2):268-75.
1998: Maria Luisa Barbaccia; Alessandra Concas; Mariangela Serra; Giovanni Biggio
Stress and neurosteroids in adult and aged rats.
Experimental gerontology 1998;33(7-8):697-712.
1998: Alessandra Concas; Maria Cristina Mostallino; Patrizia Porcu; Paolo Follesa; Maria Luisa Barbaccia; M Trabucchi; Robert H Purdy; P Grisenti; Giovanni Biggio
Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13284-9.
1998: Paolo Follesa; Stefano Floris; G Tuligi; Maria Cristina Mostallino; Alessandra Concas; Giovanni Biggio
Molecular and functional adaptation of the GABA(A) receptor complex during pregnancy and after delivery in the rat brain.
The European journal of neuroscience 1998;10(9):2905-12.
1998: Alessandra Concas; Paola Pierobon; Maria Cristina Mostallino; Patrizia Porcu; Giuseppe Marino; Rosario Minei; Giovanni Biggio
Modulation of gamma-aminobutyric acid (GABA) receptors and the feeding response by neurosteroids in Hydra vulgaris.
Neuroscience 1998;85(3):979-88.
1998: Enrico Sanna; Costantino Motzo; M Usala; D Pau; E Cagetti; Giovanni Biggio
Functional changes in rat nigral GABA(A) receptors induced by degeneration of the striatonigral GABAergic pathway: an electrophysiological study of receptors incorporated into Xenopus oocytes.
Journal of neurochemistry 1998;70(6):2539-44.
1998: Giuseppe Trapani; Andrea Latrofa; Massimo Franco; Cosimo Altomare; Enrico Sanna; M Usala; Giovanni Biggio; Gaetano Liso
Propofol analogues. Synthesis, relationships between structure and affinity at GABAA receptor in rat brain, and differential electrophysiological profile at recombinant human GABAA receptors.
Journal of medicinal chemistry 1998;41(11):1846-54.
1998: Luisa Savini; Paola Massarelli; C Nencini; Cesare Pellerano; Giovanni Biggio; A Maciocco; G Tuligi; Antonio Carrieri; N Cinone; Angelo Carotti
High affinity central benzodiazepine receptor ligands: synthesis and structure-activity relationship studies of a new series of pyrazolo[4,3-c]quinolin-3-ones.
Bioorganic & medicinal chemistry 1998;6(4):389-99.
1998: Carmen Ghiani; Laura Dazzi; Elisabetta Maciocco; Giovanna Flore; G Maira; Giovanni Biggio
Antagonism by abecarnil of enhanced acetylcholine release in the rat brain during anticipation but not consumption of food.
Pharmacology, biochemistry, and behavior 1998;59(3):657-62.
1998: Assunta Imperato; Laura Dazzi; G Carta; G Colombo; Giovanni Biggio
Rapid increase in basal acetylcholine release in the hippocampus of freely moving rats induced by withdrawal from long-term ethanol intoxication.
Brain research 1998;784(1-2):347-50.
1997: Giuseppe Trapani; Massimo Franco; L Ricciardi; Andrea Latrofa; G Genchi; Enrico Sanna; Federica Tuveri; E Cagetti; Giovanni Biggio; Gaetano Liso
Synthesis and binding affinity of 2-phenylimidazo[1,2-alpha]pyridine derivatives for both central and peripheral benzodiazepine receptors. A new series of high-affinity and selective ligands for the peripheral type.
Journal of medicinal chemistry 1997;40(19):3109-18.
1997: Laura Dazzi; Mariangela Serra; M L Porceddu; A Sanna; M F Chessa; Giovanni Biggio
Enhancement of basal and pentylenetetrazol (PTZ)-stimulated dopamine release in the brain of freely moving rats by PTZ-induced kindling.
Synapse (New York, N.Y.) 1997;26(4):351-8.
1997: Mariangela Serra; R Cuccu; Carmen Ghiani; Maria Giuseppina Pisu; A Murgia; Giovanni Biggio
Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam.
Neurochemical research 1997;22(6):693-7.
1997: Costantino Motzo; M L Porceddu; Laura Dazzi; A Sanna; Mariangela Serra; Giovanni Biggio
Enhancement by flumazenil of dopamine release in the nucleus accumbens of rats repeatedly exposed to diazepam or imidazenil.
Psychopharmacology 1997;131(1):34-9.
1997: Alessandra Padiglia; Rosaria Medda; Anita Lorrai; Giovanni Biggio; E Sanna; Giovanni Floris
Modulation of 6-hydroxydopamine oxidation by various proteins.
Biochemical pharmacology 1997;53(8):1065-8.
1997: Maria Luisa Barbaccia; G Roscetti; M Trabucchi; Robert H Purdy; Maria Cristina Mostallino; Alessandra Concas; Giovanni Biggio
The effects of inhibitors of GABAergic transmission and stress on brain and plasma allopregnanolone concentrations.
British journal of pharmacology 1997;120(8):1582-8.
1997: Mariangela Serra; Laura Dazzi; Maria Giuseppina Pisu; E Cagetti; Giovanni Biggio
Reversal of a selective decrease in hippocampal acetylcholine release, but not of the persistence of kindling, after discontinuation of long-term pentylenetetrazol administration in rats.
Brain research 1997;751(1):175-9.
1997: Enrico Sanna; A Murgia; A Casula; Giovanni Biggio
Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes.
Molecular pharmacology 1997;51(3):484-90.
1997: Mariangela Serra; Laura Dazzi; E Cagetti; M F Chessa; Maria Giuseppina Pisu; A Sanna; Giovanni Biggio
Effect of pentylenetetrazole-induced kindling on acetylcholine release in the hippocampus of freely moving rats.
Journal of neurochemistry 1997;68(1):313-8.
1996: Enrico Sanna; Costantino Motzo; A Murgia; F Amato; T Deserra; Giovanni Biggio
Expression of native GABAA receptors in Xenopus oocytes injected with rat brain synaptosomes.
Journal of neurochemistry 1996;67(5):2212-4.
1996: Giuseppe Trapani; Massimo Franco; Andrea Latrofa; Angelo Carotti; S Cellamare; Mariangela Serra; Carmen Ghiani; G Tuligi; Giovanni Biggio; Gaetano Liso
Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolo[2,1-b]-benzothiazol-, -thiazol- or -oxazol-1-ones in rodents.
The Journal of pharmacy and pharmacology 1996;48(8):834-40.
1996: Carmen Ghiani; G Tuligi; Elisabetta Maciocco; Mariangela Serra; Enrico Sanna; Giovanni Biggio
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
Biochemical pharmacology 1996;51(11):1527-34.
1996: Alessandra Concas; Maria Cristina Mostallino; Chiara Perra; R Lener; G Roscetti; Maria Luisa Barbaccia; Robert H Purdy; Giovanni Biggio
Functional correlation between allopregnanolone and [35S]-TBPS binding in the brain of rats exposed to isoniazid, pentylenetetrazol or stress.
British journal of pharmacology 1996;118(4):839-46.
1996: Maria Luisa Barbaccia; G Roscetti; Francesca Bolacchi; Alessandra Concas; Maria Cristina Mostallino; Robert H Purdy; Giovanni Biggio
Stress-induced increase in brain neuroactive steroids: antagonism by abecarnil.
Pharmacology, biochemistry, and behavior 1996;54(1):205-10.
1996: Laura Dazzi; A Sanna; E Cagetti; Alessandra Concas; Giovanni Biggio
Inhibition by the neurosteroid allopregnanolone of basal and stress-induced acetylcholine release in the brain of freely moving rats.
Brain research 1996;710(1-2):275-80.
1996: Maria Luisa Barbaccia; G Roscetti; Marco Trabucchi; Maria Cristina Mostallino; Alessandra Concas; Robert H Purdy; Giovanni Biggio
Time-dependent changes in rat brain neuroactive steroid concentrations and GABAA receptor function after acute stress.
Neuroendocrinology 1996;63(2):166-72.
1996: Alessandra Concas; M P Mascia; T Cuccheddu; Stefano Floris; Maria Cristina Mostallino; Chiara Perra; Stefania Satta; Giovanni Biggio
Chronic ethanol intoxication enhances [3H]CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum.
Pharmacology, biochemistry, and behavior 1996;53(2):249-55.
1996: Costantino Motzo; M L Porceddu; Alessandra Concas; Laura Dazzi; Giovanna Flore; G Maira; Giovanni Biggio
Inhibition of basal and stress-induced dopamine release in the cerebral cortex and nucleus accumbens of freely moving rats by the neurosteroid allopregnanolone.
Journal of psychopharmacology (Oxford, England) 1996;10(4):266-72.
1996: Enrico Sanna; A Murgia; A Casula; M Usala; Elisabetta Maciocco; G Tuligi; Giovanni Biggio
Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit.
Neuropharmacology 1996;35(12):1753-60.
1996: Maria Luisa Barbaccia; G Roscetti; Marco Trabucchi; Robert H Purdy; Maria Cristina Mostallino; Chiara Perra; Alessandra Concas; Giovanni Biggio
Isoniazid-induced inhibition of GABAergic transmission enhances neurosteroid content in the rat brain.
Neuropharmacology 1996;35(9-10):1299-305.
1995: Mariangela Serra; Carmen Ghiani; Costantino Motzo; M L Porceddu; Giovanni Biggio
Antagonism of isoniazid-induced convulsions by abecarnil in mice tolerant to diazepam.
Pharmacology, biochemistry, and behavior 1995;52(2):249-54.
1995: Laura Dazzi; Costantino Motzo; G Maira; A Sanna; Mariangela Serra; Giovanni Biggio
Enhancement of acetylcholine release by flumazenil in the hippocampus of rats chronically treated with diazepam but not with imidazenil or abecarnil.
Psychopharmacology 1995;121(2):180-5.
1995: Laura Dazzi; Costantino Motzo; Assunta Imperato; Mariangela Serra; Gian Luigi Gessa; Giovanni Biggio
Modulation of basal and stress-induced release of acetylcholine and dopamine in rat brain by abecarnil and imidazenil, two anxioselective gamma-aminobutyric acidA receptor modulators.
The Journal of pharmacology and experimental therapeutics 1995;273(1):241-7.
1995: T Cuccheddu; Stefano Floris; Mariangela Serra; M L Porceddu; Enrico Sanna; Giovanni Biggio
Proconflict effect of carbon dioxide inhalation in rats.
Life sciences 1995;56(16):PL321-4.
1995: Paola Pierobon; Alessandra Concas; G Santoro; G Marino; Rosario Minei; A Pannaccione; Maria Cristina Mostallino; Giovanni Biggio
Biochemical and functional identification of GABA receptors in Hydra vulgaris.
Life sciences 1995;56(18):1485-97.
1994: Mariangela Serra; Carmen Ghiani; S Spano; Giovanni Biggio
Felbamate antagonizes isoniazid- and FG 7142-induced reduction of GABAA receptor function in mouse brain.
European journal of pharmacology 1994;265(3):185-8.
1994: Alessandra Concas; Mariangela Serra; G Santoro; Elisabetta Maciocco; T Cuccheddu; Giovanni Biggio
The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines.
Naunyn-Schmiedeberg's archives of pharmacology 1994;350(3):294-300.
1994: Maria Luisa Barbaccia; G Roscetti; Marco Trabucchi; T Cuccheddu; Alessandra Concas; Giovanni Biggio
Neurosteroids in the brain of handling-habituated and naive rats: effect of CO2 inhalation.
European journal of pharmacology 1994;261(3):317-20.
1994: Assunta Imperato; Laura Dazzi; Mariangela Serra; Gian Luigi Gessa; Giovanni Biggio
Differential effects of abecarnil on basal release of acetylcholine and dopamine in the rat brain.
European journal of pharmacology 1994;261(1-2):205-8.
1994: Mariangela Serra; Carmen Ghiani; Costantino Motzo; M L Porceddu; Giovanni Biggio
Long-term treatment with abecarnil fails to induce tolerance in mice.
European journal of pharmacology 1994;259(1):1-6.
1994: Assunta Imperato; Laura Dazzi; Maria Carmen Obinu; Gian Luigi Gessa; Giovanni Biggio
The benzodiazepine receptor antagonist flumazenil increases acetylcholine release in rat hippocampus.
Brain research 1994;647(1):167-71.
1994: Alessandra Concas; T Cuccheddu; Stefano Floris; M P Mascia; Giovanni Biggio
2-Chloro-N6-cyclopentyladenosine (CCPA), an adenosine A1 receptor agonist, suppresses ethanol withdrawal syndrome in rats.
Alcohol and alcoholism (Oxford, Oxfordshire) 1994;29(3):261-4.
1994: Alessandra Concas; G Santoro; M P Mascia; Elisabetta Maciocco; Laura Dazzi; Giovanni Biggio
Effects of propofol, pentobarbital and alphaxalone on t-[35S]butylbicyclophosphorothionate binding in rat cerebral cortex.
European journal of pharmacology 1994;267(2):207-13.
1994: Mariangela Serra; Carmen Ghiani; Costantino Motzo; T Cuccheddu; Stefano Floris; P Giusti; Giovanni Biggio
Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor function.
The Journal of pharmacology and experimental therapeutics 1994;269(1):32-8.
1994: Mariangela Serra; Carmen Ghiani; M C Foddi; Costantino Motzo; Giovanni Biggio
NMDA receptor function is enhanced in the hippocampus of aged rats.
Neurochemical research 1994;19(4):483-7.
1994: Carmen Ghiani; Mariangela Serra; Costantino Motzo; P Giusti; T Cuccheddu; M L Porceddu; Giovanni Biggio
Chronic administration of an anticonvulsant dose of imidazenil fails to induce tolerance of GABAA receptor function in mice.
European journal of pharmacology 1994;254(3):299-302.
1993: Alessandra Concas; G Santoro; M P Mascia; Elisabetta Maciocco; Laura Dazzi; E Ongini; Giovanni Biggio
Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain.
The Journal of pharmacology and experimental therapeutics 1993;267(2):844-51.
1993: Assunta Imperato; Laura Dazzi; Maria Carmen Obinu; Gian Luigi Gessa; Giovanni Biggio
Inhibition of hippocampal acetylcholine release by benzodiazepines: antagonism by flumazenil.
European journal of pharmacology 1993;238(1):135-7.
1993: Alessandra Concas; Enrico Sanna; T Cuccheddu; M P Mascia; G Santoro; Elisabetta Maciocco; Giovanni Biggio
Carbon dioxide inhalation, stress and anxiogenic drugs reduce the function of GABAA receptor complex in the rat brain.
Progress in neuro-psychopharmacology & biological psychiatry 1993;17(4):651-61.
1993: Enrico Sanna; Mariangela Serra; A Cossu; Giancarlo Colombo; Paolo Follesa; T Cuccheddu; Alessandra Concas; Giovanni Biggio
Chronic ethanol intoxication induces differential effects on GABAA and NMDA receptor function in the rat brain.
Alcoholism, clinical and experimental research 1993;17(1):115-23.
1993: Mariangela Serra; Carmen Ghiani; Costantino Motzo; Giovanni Biggio
Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors.
Psychopharmacology series 1993;11():62-78.
1992: Mariangela Serra; M C Foddi; Carmen Ghiani; Maria Antonietta Melis; Costantino Motzo; Alessandra Concas; Enrico Sanna; Giovanni Biggio
Pharmacology of gamma-aminobutyric acidA receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta-carboline derivative abecarnil.
The Journal of pharmacology and experimental therapeutics 1992;263(3):1360-8.
1992: Enrico Sanna; T Cuccheddu; Mariangela Serra; Alessandra Concas; Giovanni Biggio
Carbon dioxide inhalation reduces the function of GABAA receptors in the rat brain.
European journal of pharmacology 1992;216(3):457-8.
1992: Osvaldo Giorgi; Monica Pibiri; R Dal Toso; G Toffano; Giovanni Biggio
Differential turnover rates of D1 dopamine receptors in the brain and retina of adult and senescent rats.
Neurochemistry international 1992;20 Suppl():171S-173S.
1992: Giovanni Biggio; M Cibin; Marco Diana; Fabio Fadda; Santo Davide Ferrara; L Gallimberti; Gian Luigi Gessa; Giampaolo Mereu; Zvani L Rossetti; Mariangela Serra
Suppression of voluntary alcohol intake in rats and alcoholics by gamma-hydroxybutyric acid: a non-GABAergic mechanism.
Advances in biochemical psychopharmacology 1992;47():281-8.
1992: Enrico Sanna; Mariangela Serra; A Cossu; Giancarlo Colombo; Paolo Follesa; Giovanni Biggio
GABAA and NMDA receptor function during chronic administration of ethanol.
Advances in biochemical psychopharmacology 1992;47():317-24.
1992: Alessandra Concas; G Santoro; M P Mascia; Elisabetta Maciocco; Giovanni Biggio
The general anesthetic propofol: a biochemical tool to study the function of the GABA-coupled chloride channel.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():685A-686A.
1992: Alessandra Concas; Mariangela Serra; Enrico Sanna; S Pepitoni; M P Mascia; Giovanni Biggio
Involvement of GABA-dependent chloride channel in the action of anticonvulsant and convulsant drugs.
Epilepsy research. Supplement 1992;8():77-85.
1992: Alessandra Concas; G Santoro; M P Mascia; Mariangela Serra; Enrico Sanna; Giovanni Biggio
The action of the general anesthetic propofol on GABAA receptors.
Advances in biochemical psychopharmacology 1992;47():349-63.
1991: V A Peduto; Alessandra Concas; G Santoro; Giovanni Biggio; Gian Luigi Gessa
Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain.
Anesthesiology 1991;75(6):1000-9.
1991: Osvaldo Giorgi; Monica Pibiri; Giovanni Biggio
Differential turnover rates of D1 dopamine receptors in the retina and in distinct areas of the rat brain.
Journal of neurochemistry 1991;57(3):754-9.
1991: Osvaldo Giorgi; Monica Pibiri; E Ongini; M Trampus; Giovanni Biggio
The neutral endopeptidase-24.11 (enkephalinase) inhibitor, SCH 32615, increases dopamine metabolism in the nucleus accumbens of the rat.
European journal of pharmacology 1991;196(2):137-42.
1991: Alessandra Concas; G Santoro; Mariangela Serra; Enrico Sanna; Giovanni Biggio
Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors.
Brain research 1991;542(2):225-32.
1991: Enrico Sanna; Alessandra Concas; Mariangela Serra; G Santoro; Giovanni Biggio
Ex vivo binding of t-[35S )butylbicyclophosphorothionate: a biochemical tool to study the pharmacology of ethanol at the gamma-aminobutyric acid-coupled chloride channel.
The Journal of pharmacology and experimental therapeutics 1991;256(3):922-8.
1991: Alessandra Concas; M P Mascia; Enrico Sanna; G Santoro; Mariangela Serra; Giovanni Biggio
"In vivo" administration of valproate decreases t-[35S]butylbicyclophosphorothionate binding in the rat brain.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(3):296-300.
1991: Mariangela Serra; Enrico Sanna; Alessandra Concas; C Foddi; Giovanni Biggio
Foot-shock stress enhances the increase of [35S]TBPS binding in the rat cerebral cortex and the convulsions induced by isoniazid.
Neurochemical research 1991;16(1):17-22.
1991: Mariangela Serra; Enrico Sanna; C Foddi; Alessandra Concas; Giovanni Biggio
Failure of gamma-hydroxybutyrate to alter the function of the GABAA receptor complex in the rat cerebral cortex.
Psychopharmacology 1991;104(3):351-5.
1991: Giovanni Biggio; Enrico Sanna; Mariangela Serra; G P Serra; Alessandra Concas
"In vivo" inhibition of GABAergic transmission increases 35S-TBPS binding in the rat brain.
Advances in experimental medicine and biology 1991;287():391-404.
1990: Alessandra Concas; G Santoro; M P Mascia; Mariangela Serra; Enrico Sanna; Giovanni Biggio
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
Journal of neurochemistry 1990;55(6):2135-8.
1990: Osvaldo Giorgi; Giovanni Biggio
Selective unilateral inactivation of striatal D1 and D2 dopamine receptor subtypes by EEDQ: turning behavior elicited by D2 dopamine receptor agonists.
Brain research 1990;533(1):53-9.
1990: Maria G Corda; Osvaldo Giorgi; B Longoni; M Orlandi; Giovanni Biggio
Decrease in the function of the gamma-aminobutyric acid-coupled chloride channel produced by the repeated administration of pentylenetetrazol to rats.
Journal of neurochemistry 1990;55(4):1216-21.
1990: Enrico Sanna; Alessandra Concas; Mariangela Serra; Giovanni Biggio
Enhancement of GABA-dependent chloride channel by "in vivo" administration of ethanol.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22 Suppl 1():91-2.
1990: Giampaolo Mereu; G Carcangiu; Alessandra Concas; N Passino; Giovanni Biggio
Reduction of reticulata neuronal activity by zolpidem and alpidem, two imidazopyridines with high affinity for type I benzodiazepine receptors.
European journal of pharmacology 1990;179(3):339-45.
1990: Alessandra Concas; Enrico Sanna; M P Mascia; Mariangela Serra; Giovanni Biggio
Diazepam enhances bicuculline-induced increase of t-[35S]butylbicyclophosphorothionate binding in unwashed membrane preparations from rat cerebral cortex.
Neuroscience letters 1990;112(1):87-91.
1990: Osvaldo Giorgi; Giovanni Biggio
Unilateral inactivation of dopamine receptors after intrastriatal injection of N-ethoxy-carbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ): a novel rotational model to investigate dopamine receptor interactions.
Pharmacology, biochemistry, and behavior 1990;35(4):877-84.
1990: M L Porceddu; G De Montis; S Pepitoni; G Toffano; Giovanni Biggio
Failure of dark adaptation to upregulate D-1 dopamine receptors in retina of senescent rats.
Neurobiology of aging 1990;11(2):105-9.
1990: Enrico Sanna; Alessandra Concas; Mariangela Serra; Giovanni Biggio
In vivo administration of ethanol enhances the function of the gamma-aminobutyric acid-dependent chloride channel in the rat cerebral cortex.
Journal of neurochemistry 1990;54(2):696-8.
1990: Osvaldo Giorgi; M L Porceddu; S Pepitoni; G P Serra; G Toffano; Giovanni Biggio
Differential effect of aging on 3H-SCH 23390 binding sites in the retina and in distinct areas of the rat brain.
Journal of neural transmission. General section 1990;82(3):157-66.
1990: Alessandra Concas; Enrico Sanna; Mariangela Serra; M P Mascia; V Santoro; Giovanni Biggio
"Ex vivo" binding of 35S-TBPS as a tool to study the pharmacology of GABAA receptors.
Advances in biochemical psychopharmacology 1990;46():89-108.
1990: Maria G Corda; Osvaldo Giorgi; M Orlandi; B Longoni; Giovanni Biggio
Chronic administration of negative modulators produces chemical kindling and GABAA receptor down-regulation.
Advances in biochemical psychopharmacology 1990;46():153-66.
1990: Giampaolo Mereu; Giovanni Biggio
Differential action of various allosteric modulators of GABAA receptor upon the spontaneous discharge rate of nigral neurons "in vivo".
Advances in biochemical psychopharmacology 1990;46():109-25.
1989: Enrico Sanna; Mariangela Serra; S Pepitoni; Giovanni Biggio
Dramatic increase in nigral t-[35S]butylbicyclophosphorothionate binding sites elicited by the degeneration of the striato-nigral GABAergic pathway: reversal by diazepam.
Brain research 1989;501(1):144-9.
1989: Maria G Corda; Osvaldo Giorgi; B Longoni; E Ongini; G Pesce; Ricardo Cruciani; Giovanni Biggio
Functional coupling of GABAA receptors and benzodiazepine recognition site subtypes in the spinal cord of the rat.
European journal of pharmacology 1989;169(2-3):205-13.
1989: Osvaldo Giorgi; Maria G Corda; Ivana Gritti; M Mariotti; E Ongini; Giovanni Biggio
Binding sites for [3H]2-oxo-quazepam in the brain of the cat: evidence for heterogeneity of benzodiazepine recognition sites.
Neuropharmacology 1989;28(7):715-8.
1989: Mariangela Serra; Enrico Sanna; Giovanni Biggio
Isoniazid, an inhibitor of GABAergic transmission, enhances [35S]TBPS binding in rat cerebral cortex.
European journal of pharmacology 1989;164(2):385-8.
1989: Maria G Corda; B Longoni; A Cau; S Paci; S Salvadori; U Laudani; Giovanni Biggio
Distribution and pharmacological properties of the GABAA/benzodiazepine/chloride ionophore receptor complex in the brain of the fish Anguilla anguilla.
Journal of neurochemistry 1989;52(4):1025-34.
1989: Osvaldo Giorgi; Maria G Corda; A Fernandez; Giovanni Biggio
The beta-carboline derivatives ZK 93426 and FG 7142 fail to precipitate abstinence signs in diazepam-dependent cats.
Pharmacology, biochemistry, and behavior 1989;32(3):671-5.
1989: Giovanni Biggio; Alessandra Concas; Maria G Corda; Mariangela Serra
Enhancement of GABAergic transmission by zolpidem, an imidazopyridine with preferential affinity for type I benzodiazepine receptors.
European journal of pharmacology 1989;161(2-3):173-80.
1989: Maria G Corda; Osvaldo Giorgi; B Longoni; Giovanni Biggio
Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat.
European journal of pharmacology 1989;159(3):233-9.
1988: S Pepitoni; M L Porceddu; G Toffano; Giovanni Biggio
3H-SCH 23390 binding in the rat retina: effect of aging and environmental lighting.
Pharmacological research communications 1988;20(12):1123-4.
1988: Alessandra Concas; Mariangela Serra; T Atsoggiu; Giovanni Biggio
Foot-shock stress and anxiogenic beta-carbolines increase t-[35S]butylbicyclophosphorothionate binding in the rat cerebral cortex, an effect opposite to anxiolytics and gamma-aminobutyric acid mimetics.
Journal of neurochemistry 1988;51(6):1868-76.
1988: B Longoni; Maria G Corda; Giovanni Biggio
Functional interaction between GABA receptors and type I benzodiazepine recognition sites in the spinal cord of the rat.
Pharmacological research communications 1988;20(12):1089-90.
1988: Osvaldo Giorgi; Maria G Corda; Giovanni Biggio
Ro 15-4513, like anxiogenic beta-carbolines, increases dopamine metabolism in the prefrontal cortex of the rat.
European journal of pharmacology 1988;156(1):71-5.
1988: Osvaldo Giorgi; Maria G Corda; A Fernández; Giovanni Biggio
The abstinence syndrome in diazepam-dependent cats is precipitated by Ro 15-1788 and Ro 15-4513 but not by the benzodiazepine receptor antagonist ZK 93426.
Neuroscience letters 1988;88(2):206-10.
1988: Maria G Corda; Osvaldo Giorgi; B Longoni; Giovanni Biggio
Decreased sensitivity to diazepam induced by chronic administration of FG 7142.
Neuroscience letters 1988;86(2):219-24.
1988: Maria G Corda; Osvaldo Giorgi; B Longoni; E Ongini; A Barnett; S Montaldo; Giovanni Biggio
gamma-Aminobutyric acid and pentobarbital enhance 2-[3H]oxoquazepam binding to type I benzodiazepine recognition sites in rat and human brain.
Journal of neurochemistry 1988;50(3):681-7.
1988: Maria G Corda; Osvaldo Giorgi; B M Longoni; E Ongini; S Montaldo; F Paribello; Giovanni Biggio
Characterization of 3H-2-oxo-quazepam binding in the human brain.
Progress in neuro-psychopharmacology & biological psychiatry 1988;12(5):701-12.
1988: Alessandra Concas; Mariangela Serra; Maria G Corda; Giovanni Biggio
Changes of 36Cl- flux and 35S-TBPS binding induced by stress and gabaergic drugs.
Advances in biochemical psychopharmacology 1988;45():227-46.
1988: Maria G Corda; Osvaldo Giorgi; B Longoni; E Ongini; S Montaldo; Giovanni Biggio
Preferential affinity of 3H-2-oxo-quazepam for type I benzodiazepine recognition sites in the human brain.
Life sciences 1988;42(2):189-97.
1988: Alessandra Concas; S Pepitoni; T Atsoggiu; G Toffano; Giovanni Biggio
Aging reduces the GABA-dependent 36Cl- flux in rat brain membrane vesicles.
Life sciences 1988;43(22):1761-71.
1988: Maria G Corda; Osvaldo Giorgi; B Longoni; A Fernandez; Giovanni Biggio
Increased sensitivity to inverse agonists and decreased GABA-stimulated chloride influx induced by chronic treatment with FG 7142.
Advances in biochemical psychopharmacology 1988;45():293-306.
1987: M L Porceddu; G De Montis; S Mele; E Ongini; Giovanni Biggio
D1 dopamine receptors in the rat retina: effect of dark adaptation and chronic blockade by SCH 23390.
Brain research 1987;424(2):264-71.
1987: Osvaldo Giorgi; G De Montis; M L Porceddu; S Mele; G Calderini; G Toffano; Giovanni Biggio
Developmental and age-related changes in D1-dopamine receptors and dopamine content in the rat striatum.
Brain research 1987;432(2):283-90.
1987: Maria G Corda; Osvaldo Giorgi; S Mele; Giovanni Biggio
Enhanced sensitivity to beta-carboline inverse agonists in rats chronically treated with FG 7142.
Brain research bulletin 1987;19(3):379-85.
1987: Giovanni Biggio; Alessandra Concas; S Mele; Maria G Corda
Changes in GABAergic transmission induced by stress, anxiogenic and anxiolytic beta-carbolines.
Brain research bulletin 1987;19(3):301-8.
1987: M L Porceddu; Osvaldo Giorgi; G De Montis; S Mele; L Cocco; E Ongini; Giovanni Biggio
6-Hydroxydopamine-induced degeneration of nigral dopamine neurons: differential effect on nigral and striatal D-1 dopamine receptors.
Life sciences 1987;41(6):697-706.
1987: Francesco Marrosu; Giovanni Marrosu; M G Rachel; Giovanni Biggio
Paradoxical reactions elicited by diazepam in children with classic autism.
Functional neurology 1987;2(3):355-61.
1987: Maria G Corda; Osvaldo Giorgi; B Longoni; Giampaolo Mereu; Giovanni Biggio
Enhancement of gamma-aminobutyric acid binding by the anxiolytic beta-carbolines ZK 93423 and ZK 91296.
Journal of neurochemistry 1987;48(5):1355-8.
1987: Alessandra Concas; S Mele; Giovanni Biggio
Foot shock stress decreases chloride efflux from rat brain synaptoneurosomes.
European journal of pharmacology 1987;135(3):423-7.
1986: M L Porceddu; Osvaldo Giorgi; E Ongini; S Mele; Giovanni Biggio
3H-SCH 23390 binding sites in the rat substantia nigra: evidence for a presynaptic localization and innervation by dopamine.
Life sciences 1986;39(4):321-8.
1986: M G Corda; A Concas; M L Porceddu; Enrico Sanna; Giovanni Biggio
Striato-nigral denervation increases type II benzodiazepine receptors in the substantia nigra of the rat.
Neuropharmacology 1986;25(1):59-62.
1985: M L Porceddu; M G Corda; Enrico Sanna; Giovanni Biggio
Increase in nigral type II benzodiazepine recognition sites following striatonigral denervation.
European journal of pharmacology 1985;112(2):265-7.
1984: S Montaldo; M Serra; Alessandra Concas; Maria G Corda; S Mele; Giovanni Biggio
Evidence for the presence of benzodiazepine receptor subclasses in different areas of the human brain.
Neuroscience letters 1984;52(3):263-8.
1980: Giovanni Biggio; M G Corda; G De Montis; E Stefanini; Gian Luigi Gessa
Kainic acid differentiates GABA receptors from benzodiazepine receptors in the rat cerebellum.
Brain research 1980;193(2):589-93.