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Pedro Romero
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Chemicals & Drugs
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93
Cerottini, Jean-Charles
57
Valmori, Danila
50
Speiser, Daniel
49
Rimoldi, Donata
39
Guillaume, Philippe
39
Liénard, Danielle
31
Pittet, Mikaël
26
Rufer, Nathalie
22
Luescher, Immanuel
21
Dutoit, Valérie
19
Rubio-Godoy, Verena
19
Speiser, Daniel
17
Lejeune, Ferdy
16
Zippelius, Alfred
14
Corradin, Giampietro
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All Publications
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2009: Jandus Camilla; Speiser Daniel; Romero Pedro
Recent advances and hurdles in melanoma immunotherapy.
Pigment cell & melanoma research 2009;22(6):711-23.
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2009: Jandus Camilla; Bioley Gilles; Dojcinovic Danijel; Derré Laurent; Baitsch Lukas; Wieckowski Sébastien; Rufer Nathalie; Kwok William W; Tiercy Jean-Marie; Luescher Immanuel F; Speiser Daniel E; Romero Pedro
Tumor antigen-specific FOXP3+ CD4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts.
Cancer research 2009;69(20):8085-93.
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2009: Wieckowski Sébastien; Baumgaertner Petra; Corthesy Patricia; Voelter Verena; Romero Pedro; Speiser Daniel E; Rufer Nathalie
Fine structural variations of alphabetaTCRs selected by vaccination with natural versus altered self-antigen in melanoma patients.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(8):5397-406.
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2009: Iancu Emanuela M; Corthesy Patricia; Baumgaertner Petra; Devevre Estelle; Voelter Verena; Romero Pedro; Speiser Daniel E; Rufer Nathalie
Clonotype selection and composition of human CD8 T cells specific for persistent herpes viruses varies with differentiation but is stable over time.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):319-31.
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2009: Touvrey Cédric; Derré Laurent; Devevre Estelle; Corthesy Patricia; Romero Pedro; Rufer Nathalie; Speiser Daniel E
Dominant human CD8 T cell clonotypes persist simultaneously as memory and effector cells in memory phase.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):6718-26.
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2009: Bricard Gabriel; Cesson Valerie; Devevre Estelle; Bouzourene Hanifa; Barbey Catherine; Rufer Nathalie; Im Jin S; Alves Pedro M; Martinet Olivier; Halkic Nermin; Cerottini Jean-Charles; Romero Pedro; Porcelli Steven A; Macdonald H Robson; Speiser Daniel E
Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):5140-51.
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2009: Salaun Bruno; Greutert Maude; Romero Pedro
Toll-like receptor 3 is necessary for dsRNA adjuvant effects.
Vaccine 2009;27(12):1841-7.
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2009: Brandes Marlène; Willimann Katharina; Bioley Gilles; Lévy Nicole; Eberl Matthias; Luo Ming; Tampé Robert; Lévy Frédéric; Romero Pedro; Moser Bernhard
Cross-presenting human gammadelta T cells induce robust CD8+ alphabeta T cell responses.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(7):2307-12.
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2008: Jandus Camilla; Bioley Gilles; Speiser Daniel E; Romero Pedro
Selective accumulation of differentiated FOXP3(+) CD4 (+) T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood.
Cancer immunology, immunotherapy : CII 2008;57(12):1795-805.
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2008: Derré Laurent; Bruyninx Marc; Baumgaertner Petra; Ferber Mathias; Schmid Daphné; Leimgruber Antoine; Zoete Vincent; Romero Pedro; Michielin Olivier; Speiser Daniel E; Rufer Nathalie
Distinct sets of alphabeta TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):15010-5.
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2008: Jandus Camilla; Bioley Gilles; Rivals Jean-Paul; Dudler Jean; Speiser Daniel; Romero Pedro
Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides.
Arthritis and rheumatism 2008;58(8):2307-17.
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2008: Voelter Verena; Rufer Nathalie; Reynard Severine; Greub Gilbert; Brookes Roger; Guillaume Philippe; Grosjean Frederic; Fagerberg Theres; Michelin Olivier; Rowland-Jones Sarah; Pinilla Clemencia; Leyvraz Serge; Romero Pedro; Appay Victor
Characterization of Melan-A reactive memory CD8+ T cells in a healthy donor.
International immunology 2008;20(8):1087-96.
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2008: Adams Sylvia; Lowes Michelle A; O'Neill David W; Schachterle Stephen; Romero Pedro; Bhardwaj Nina
Lack of functionally active Melan-A(26-35)-specific T cells in the blood of HLA-A2+ vitiligo patients.
The Journal of investigative dermatology 2008;128(8):1977-80.
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2008: Speiser Daniel E; Baumgaertner Petra; Voelter Verena; Devevre Estelle; Barbey Catherine; Rufer Nathalie; Romero Pedro
Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3849-54.
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2008: Romero Pedro
Current state of vaccine therapies in non-small-cell lung cancer.
Clinical lung cancer 2008;9 Suppl 1():S28-36.
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2008: Voelter Verena; Pica Alessia; Laurent Julien; Rimoldi Donata; Bouzourene Hanifa; Sajadi Ali; Matter Maurice; Romero Pedro; Rufer Nathalie; Speiser Daniel E
An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain.
Cancer immunity : a journal of the Academy of Cancer Immunology 2008;8():6.
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2007: Salaun Bruno; Romero Pedro; Lebecque Serge
Toll-like receptors' two-edged sword: when immunity meets apoptosis.
European journal of immunology 2007;37(12):3311-8.
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2007: Derré Laurent; Ferber Mathias; Touvrey Cédric; Devevre Estelle; Zoete Vincent; Leimgruber Antoine; Romero Pedro; Michielin Olivier; Lévy Frédéric; Speiser Daniel E
A novel population of human melanoma-specific CD8 T cells recognizes Melan-AMART-1 immunodominant nonapeptide but not the corresponding decapeptide.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7635-45.
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2007: Appay Victor; Bosio Andreas; Lokan Stefanie; Wiencek Yvonne; Biervert Christian; Küsters Daniel; Devevre Estelle; Speiser Daniel; Romero Pedro; Rufer Nathalie; Leyvraz Serge
Sensitive gene expression profiling of human T cell subsets reveals parallel post-thymic differentiation for CD4+ and CD8+ lineages.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7406-14.
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2007: Alves Pedro M S; Viatte Sebastien; Fagerberg Theres; Michielin Olivier; Bricard Gabriel; Bouzourene Hanifa; Vuilleumier Henri; Kruger Thorsten; Givel Jean-Claude; Lévy Frédéric; Speiser Daniel E; Cerottini Jean-Charles; Romero Pedro
Immunogenicity of the carcinoembryonic antigen derived peptide 694 in HLA-A2 healthy donors and colorectal carcinoma patients.
Cancer immunology, immunotherapy : CII 2007;56(11):1795-805.
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2007: Derré Laurent; Bruyninx Marc; Baumgaertner Petra; Devevre Estelle; Corthesy Patricia; Touvrey Cédric; Mahnke Yolanda D; Pircher Hanspeter; Voelter Verena; Romero Pedro; Speiser Daniel E; Rufer Nathalie
In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2368-79.
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2007: Salaun Bruno; Lebecque Serge; Matikainen Sampsa; Rimoldi Donata; Romero Pedro
Toll-like receptor 3 expressed by melanoma cells as a target for therapy?
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(15 Pt 1):4565-74.
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2007: Alves Pedro M S; Lévy Nicole; Bouzourene Hanifa; Viatte Sébastien; Bricard Gabriel; Ayyoub Maha; Vuilleumier Henri; Givel Jean-Claude R; Halkic Nermin; Speiser Daniel E; Romero Pedro; Lévy Frédéric
Molecular and immunological evaluation of the expression of cancer/testis gene products in human colorectal cancer.
Cancer immunology, immunotherapy : CII 2007;56(6):839-47.
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2007: Romero Pedro; Zippelius Alfred; Kurth Isabel; Pittet Mikaël J; Touvrey Cédric; Iancu Emanuela M; Corthesy Patricia; Devevre Estelle; Speiser Daniel E; Rufer Nathalie
Four functionally distinct populations of human effector-memory CD8+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4112-9.
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2007: Barbey Catherine; Baumgaertner Petra; Devevre Estelle; Rubio-Godoy Verena; Derre Laurent; Bricard Gabriel; Guillaume Philippe; Luescher Immanuel F; Liénard Danielle; Cerottini Jean-Charles; Romero Pedro; Rufer Nathalie; Speiser Daniel E
IL-12 controls cytotoxicity of a novel subset of self-antigen-specific human CD28+ cytolytic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3566-74.
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2007: Appay Victor; Voelter Verena; Rufer Nathalie; Reynard Sévérine; Jandus Camilla; Gasparini Danielle; Lienard Danielle; Speiser Daniel E; Schneider Philippe; Cerottini Jean-Charles; Romero Pedro; Leyvraz Serge
Combination of transient lymphodepletion with busulfan and fludarabine and peptide vaccination in a phase I clinical trial for patients with advanced melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(2):240-50.
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2006: Tabiasco Julie; Devêvre Estelle; Rufer Nathalie; Salaun Bruno; Cerottini Jean-Charles; Speiser Daniel; Romero Pedro
Human effector CD8+ T lymphocytes express TLR3 as a functional coreceptor.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8708-13.
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2006: Bioley Gilles; Jandus Camilla; Tuyaerts Sandra; Rimoldi Donata; Kwok William W; Speiser Daniel E; Tiercy Jean-Marie; Thielemans Kris; Cerottini Jean-Charles; Romero Pedro
Melan-A/MART-1-specific CD4 T cells in melanoma patients: identification of new epitopes and ex vivo visualization of specific T cells by MHC class II tetramers.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):6769-79.
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2006: Appay Victor; Jandus Camilla; Voelter Verena; Reynard Severine; Coupland Sarah E; Rimoldi Donata; Lienard Danielle; Guillaume Philippe; Krieg Arthur M; Cerottini Jean-Charles; Romero Pedro; Leyvraz Serge; Rufer Nathalie; Speiser Daniel E
New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1670-8.
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2006: Speiser Daniel E; Baumgaertner Petra; Barbey Catherine; Rubio-Godoy Verena; Moulin Alexandre; Corthesy Patricia; Devevre Estelle; Dietrich Pierre-Yves; Rimoldi Donata; Liénard Danielle; Cerottini Jean-Charles; Romero Pedro; Rufer Nathalie
A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: spontaneous priming and efficient boosting by vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1338-48.
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2006: Appay Victor; Speiser Daniel E; Rufer Nathalie; Reynard Severine; Barbey Catherine; Cerottini Jean-Charles; Leyvraz Serge; Pinilla Clemencia; Romero Pedro
Decreased specific CD8+ T cell cross-reactivity of antigen recognition following vaccination with Melan-A peptide.
European journal of immunology 2006;36(7):1805-14.
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2006: Viatte Sebastien; Alves Pedro M; Romero Pedro
Reverse immunology approach for the identification of CD8 T-cell-defined antigens: advantages and hurdles.
Immunology and cell biology 2006;84(3):318-30.
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2006: Devêvre Estelle; Romero Pedro; Mahnke Yolanda D
LiveCount Assay: concomitant measurement of cytolytic activity and phenotypic characterisation of CD8(+) T-cells by flow cytometry.
Journal of immunological methods 2006;311(1-2):31-46.
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2006: Batard Pascal; Peterson Daniel A; Devêvre Estelle; Guillaume Philippe; Cerottini Jean-Charles; Rimoldi Donata; Speiser Daniel E; Winther Lars; Romero Pedro
Dextramers: new generation of fluorescent MHC class I/peptide multimers for visualization of antigen-specific CD8+ T cells.
Journal of immunological methods 2006;310(1-2):136-48.
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2006: Baumgaertner Petra; Rufer Nathalie; Devevre Estelle; Derre Laurent; Rimoldi Donata; Geldhof Christine; Voelter Verena; Liénard Danielle; Romero Pedro; Speiser Daniel E
Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens.
Cancer research 2006;66(4):1912-6.
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2006: Pittet Mikaël J; Gati Asma; Le Gal Frederic-Anne; Bioley Gilles; Guillaume Philippe; de Smedt Magda; Plum Jean; Speiser Daniel E; Cerottini Jean-Charles; Dietrich Pierre-Yves; Romero Pedro; Zippelius Alfred
Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2330-6.
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2006: Migliaccio Marco; Alves Pedro Miguel Sousa; Romero Pedro; Rufer Nathalie
Distinct mechanisms control human naive and antigen-experienced CD8+ T lymphocyte proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2173-82.
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2006: Appay Victor; Reynard Severine; Voelter Verena; Romero Pedro; Speiser Daniel E; Leyvraz Serge
Immuno-monitoring of CD8+ T cells in whole blood versus PBMC samples.
Journal of immunological methods 2006;309(1-2):192-9.
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2006: Romero Pedro; Cerottini Jean-Charles; Speiser Daniel E
The human T cell response to melanoma antigens.
Advances in immunology 2006;92():187-224.
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2005: Romero Pedro; Cerottini Jean-Charles; Luescher Immanuel
On the significance of CD8 alpha alpha expression for T cell memory.
European journal of immunology 2005;35(11):3092-4.
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2005: Montes M; Rufer N; Appay V; Reynard S; Pittet M J; Speiser D E; Guillaume P; Cerottini J-C; Romero P; Leyvraz S
Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy.
Clinical and experimental immunology 2005;142(2):292-302.
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2005: Walter Steffen; Bioley Gilles; Bühring Hans-Jörg; Koch Sven; Wernet Dorothee; Zippelius Alfred; Pawelec Graham; Romero Pedro; Stevanovic Stefan; Rammensee Hans-Georg; Gouttefangeas Cécile
High frequencies of functionally impaired cytokeratin 18-specific CD8+ T cells in healthy HLA-A2+ donors.
European journal of immunology 2005;35(10):2876-85.
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2005: Speiser Daniel E; Romero Pedro
Toward improved immunocompetence of adoptively transferred CD8+ T cells.
The Journal of clinical investigation 2005;115(6):1467-9.
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2005: Speiser Daniel E; Liénard Danielle; Rufer Nathalie; Rubio-Godoy Verena; Rimoldi Donata; Lejeune Ferdy; Krieg Arthur M; Cerottini Jean-Charles; Romero Pedro
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.
The Journal of clinical investigation 2005;115(3):739-46.
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2005: Bricard Gabriel; Bouzourene Hanifa; Martinet Olivier; Rimoldi Donata; Halkic Nermin; Gillet Michel; Chaubert Pascal; Macdonald H Robson; Romero Pedro; Cerottini Jean-Charles; Speiser Daniel E
Naturally acquired MAGE-A10- and SSX-2-specific CD8+ T cell responses in patients with hepatocellular carcinoma.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1709-16.
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2005: Mahnke Yolanda D; Speiser Daniel; Luescher Immanuel F; Cerottini Jean-Charles; Romero Pedro
Recent advances in tumour antigen-specific therapy: in vivo veritas.
International journal of cancer. Journal international du cancer 2005;113(2):173-8.
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2005: Michielin Olivier; Blanchet Jean-Sebastien; Fagerberg Theres; Valmori Danila; Rubio-Godoy Verena; Speiser Daniel; Ayyoub Maha; Alves Pedro; Luescher Immanuel; Gairin Jean-Edouard; Cerottini Jean-Charles; Romero Pedro
Tinkering with nature: the tale of optimizing peptide based cancer vaccines.
Cancer treatment and research 2005;123():267-91.
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2004: Chapatte Laurence; Servis Catherine; Valmori Danila; Burlet-Schiltz Odile; Dayer Johanna; Monsarrat Bernard; Romero Pedro; Lévy Frédéric
Final antigenic Melan-A peptides produced directly by the proteasomes are preferentially selected for presentation by HLA-A*0201 in melanoma cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6033-40.
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2004: Meidenbauer Norbert; Zippelius Alfred; Pittet Mikaël J; Laumer Monika; Vogl Sandra; Heymann Jana; Rehli Michael; Seliger Barbara; Schwarz Stephan; Le Gal Frederique-Anne; Dietrich Pierre Y; Andreesen Reinhard; Romero Pedro; Mackensen Andreas
High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma.
Cancer research 2004;64(17):6319-26.
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2004: Speiser Daniel E; Pittet Mikaël J; Guillaume Philippe; Lubenow Norbert; Hoffman Eric; Cerottini Jean-Charles; Romero Pedro
Ex vivo analysis of human antigen-specific CD8+ T-cell responses: quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2004;27(4):298-308.
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2004: Liénard Danielle; Rimoldi Donata; Marchand Marie; Dietrich Pierre-Yves; van Baren Nicolas; Geldhof Christine; Batard Pascal; Guillaume Philippe; Ayyoub Maha; Pittet Mikaël J; Zippelius Alfred; Fleischhauer Katharina; Lejeune Ferdy; Cerottini Jean-Charles; Romero Pedro; Speiser Daniel E
Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA.
Cancer immunity : a journal of the Academy of Cancer Immunology 2004;4():4.
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2004: Zippelius Alfred; Batard Pascal; Rubio-Godoy Verena; Bioley Gilles; Liénard Danielle; Lejeune Ferdy; Rimoldi Donata; Guillaume Philippe; Meidenbauer Norbert; Mackensen Andreas; Rufer Nathalie; Lubenow Norbert; Speiser Daniel; Cerottini Jean-Charles; Romero Pedro; Pittet Mikaël J
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.
Cancer research 2004;64(8):2865-73.
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2004: Zippelius Alfred; Bioley Gilles; Le Gal Frédérique-Anne; Rufer Nathalie; Brandes Marlene; Batard Pascal; De Smedt Magda; Plum Jean; Speiser Daniel E; Cerottini Jean-Charles; Dietrich Pierre-Yves; Romero Pedro; Pittet Mikaël J
Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):2773-7.
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2003: Speiser Daniel E; Pittet Mikaël J; Rimoldi Donata; Guillaume Philippe; Luescher Immanuel F; Liénard Danielle; Lejeune Ferdy; Cerottini Jean-Charles; Romero Pedro
Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells.
Seminars in cancer biology 2003;13(6):461-72.
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2003: Valmori Danila; Dutoit Valérie; Ayyoub Maha; Rimoldi Donata; Guillaume Philippe; Liénard Danielle; Lejeune Ferdy; Cerottini Jean-Charles; Romero Pedro; Speiser Daniel E
Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine.
Cancer immunity : a journal of the Academy of Cancer Immunology 2003;3():15.
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2003: Ayyoub Maha; Rimoldi Donata; Guillaume Philippe; Romero Pedro; Cerottini Jean-Charles; Valmori Danila; Speiser Daniel
Tumor-reactive, SSX-2-specific CD8+ T cells are selectively expanded during immune responses to antigen-expressing tumors in melanoma patients.
Cancer research 2003;63(17):5601-6.
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2003: Speiser Daniel E; Rimoldi Donata; Batard Pascal; Liénard Danielle; Lejeune Ferdy; Cerottini Jean-Charles; Romero Pedro
Disease-driven T cell activation predicts immune responses to vaccination against melanoma.
Cancer immunity : a journal of the Academy of Cancer Immunology 2003;3():12.
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2003: Rufer Nathalie; Zippelius Alfred; Batard Pascal; Pittet Mikael J; Kurth Isabel; Corthesy Patricia; Cerottini Jean-Charles; Leyvraz Serge; Roosnek Eddy; Nabholz Markus; Romero Pedro
Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions.
Blood 2003;102(5):1779-87.
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2003: Pittet Mikaël J; Rubio-Godoy Verena; Bioley Gilles; Guillaume Philippe; Batard Pascal; Speiser Daniel; Luescher Immanuel; Cerottini Jean-Charles; Romero Pedro; Zippelius Alfred
Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1844-9.
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2003: Dietrich Pierre-Yves; Le Gal Frédérique-Anne; Dutoit Valérie; Pittet Mikäel J; Trautman Lydie; Zippelius Alfred; Cognet Isabelle; Widmer Valérie; Walker Paul R; Michielin Olivier; Guillaume Philippe; Connerotte Thierry; Jotereau Francine; Coulie Pierre G; Romero Pedro; Cerottini Jean-Charles; Bonneville Marc; Valmori Danila
Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):5103-9.
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2003: Ayyoub Maha; Zippelius Alfred; Pittet Mikaël J; Rimoldi Donata; Valmori Danila; Cerottini Jean-Charles; Romero Pedro; Lejeune Ferdy; Liénard Danielle; Speiser Daniel E
Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):669-77.
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2002: Dutoit Valérie; Guillaume Philippe; Cerottini Jean-Charles; Romero Pedro; Valmori Danila
Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: crucial role of interaction kinetics on functional outcomes.
European journal of immunology 2002;32(11):3285-93.
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2002: Rubio-Godoy Verena; Dutoit Valérie; Zhao Yingdong; Simon Richard; Guillaume Philippe; Houghten Richard; Romero Pedro; Cerottini Jean-Charles; Pinilla Clemencia; Valmori Danila
Positional scanning-synthetic peptide library-based analysis of self- and pathogen-derived peptide cross-reactivity with tumor-reactive Melan-A-specific CTL.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5696-707.
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2002: Speiser Daniel E; Cerottini Jean-Charles; Romero Pedro
Can hTERT peptide (540-548) -specific CD8 T cells recognize and kill tumor cells?
Cancer immunity : a journal of the Academy of Cancer Immunology 2002;2():14.
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2002: Romero Pedro; Valmori Danila; Pittet Mikael J; Zippelius Alfred; Rimoldi Donata; Lévy Frederic; Dutoit Valérie; Ayyoub Maha; Rubio-Godoy Verena; Michielin Olivier; Guillaume Philippe; Batard Pascal; Luescher Immanuel F; Lejeune Ferdy; Liénard Danielle; Rufer Nathalie; Dietrich Pierre-Yves; Speiser Daniel E; Cerottini Jean-Charles
Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma.
Immunological reviews 2002;188():81-96.
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2002: Rubio-Godoy Verena; Ayyoub Maha; Dutoit Valerie; Servis Catherine; Schink Amy; Rimoldi Donata; Romero Pedro; Cerottini Jean-Charles; Simon Richard; Zhao Yindong; Houghten Richard A; Pinilla Clemencia; Valmori Danila
Combinatorial peptide library-based identification of peptide ligands for tumor-reactive cytolytic T lymphocytes of unknown specificity.
European journal of immunology 2002;32(8):2292-9.
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2002: Dutoit Valérie; Guillaume Philippe; Romero Pedro; Cerottini Jean-Charles; Valmori Danila
Functional analysis of HLA-A*0201/Melan-A peptide multimer+ CD8+ T cells isolated from an HLA-A*0201- donor: exploring tumor antigen allorestricted recognition.
Cancer immunity : a journal of the Academy of Cancer Immunology 2002;2():7.
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2002: Dutoit Valérie; Rubio-Godoy Verena; Pittet Mikäel J; Zippelius Alfred; Dietrich Pierre-Yves; Legal Frédérique Anne; Guillaume Philippe; Romero Pedro; Cerottini Jean-Charles; Houghten Richard A; Pinilla Clemencia; Valmori Danila
Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans.
The Journal of experimental medicine 2002;196(2):207-16.
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2002: Pittet Mikaël J; Zippelius Alfred; Valmori Danila; Speiser Daniel E; Cerottini Jean-Charles; Romero Pedro
Melan-A/MART-1-specific CD8 T cells: from thymus to tumor.
Trends in immunology 2002;23(7):325-8.
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2002: Batard Pascal; Szollosi Janos; Luescher Immanuel; Cerottini Jean-Charles; MacDonald Rob; Romero Pedro
Use of phycoerythrin and allophycocyanin for fluorescence resonance energy transfer analyzed by flow cytometry: advantages and limitations.
Cytometry 2002;48(2):97-105.
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2002: Esslinger Christoph; Romero Pedro; MacDonald H Robson
Efficient transduction of dendritic cells and induction of a T-cell response by third-generation lentivectors.
Human gene therapy 2002;13(9):1091-100.
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2002: Wirth Susanne; Bille Frédéric; Koenig Sylvain; Wehrli Nathalie; Miconnet Isabelle; Lévy Frédéric; Diggelmann Heidi; Romero Pedro; Acha-Orbea Hans
Testing mouse mammary tumor virus superantigen as adjuvant in cytotoxic T-lymphocyte responses against a melanoma tumor antigen.
International journal of cancer. Journal international du cancer 2002;99(2):201-6.
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2002: Valmori Danila; Dutoit Valerie; Schnuriger Valerie; Quiquerez Anne-Lise; Pittet Mikaël J; Guillaume Philippe; Rubio-Godoy Verena; Walker Paul R; Rimoldi Donata; Liénard Danielle; Cerottini Jean-Charles; Romero Pedro; Dietrich Pierre-Yves
Vaccination with a Melan-A peptide selects an oligoclonal T cell population with increased functional avidity and tumor reactivity.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4231-40.
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2002: Rubio-Godoy Verena; Pinilla Clemencia; Dutoit Valerie; Borras Eva; Simon Richard; Zhao Yingdong; Cerottini Jean-Charles; Romero Pedro; Houghten Richard; Valmori Danila
Toward synthetic combinatorial peptide libraries in positional scanning format (PS-SCL)-based identification of CD8+ Tumor-reactive T-Cell Ligands: a comparative analysis of PS-SCL recognition by a single tumor-reactive CD8+ cytolytic T-lymphocyte clone.
Cancer research 2002;62(7):2058-63.
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2002: Valmori Danila; Scheibenbogen Carmen; Dutoit Valerie; Nagorsen Dirk; Asemissen Anne Marie; Rubio-Godoy Verena; Rimoldi Donata; Guillaume Philippe; Romero Pedro; Schadendorf Dirk; Lipp Martin; Dietrich Pierre-Yves; Thiel Eckhard; Cerottini Jean-Charles; Liénard Danielle; Keilholz Ulrich
Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity.
Cancer research 2002;62(6):1743-50.
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2002: Speiser Daniel E; Liénard Danielle; Pittet Mikaël J; Batard Pascal; Rimoldi Donata; Guillaume Philippe; Cerottini Jean-Charles; Romero Pedro
In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells.
European journal of immunology 2002;32(3):731-41.
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2002: Zippelius Alfred; Pittet Mikaël J; Batard Pascal; Rufer Nathalie; de Smedt Magda; Guillaume Philippe; Ellefsen Kim; Valmori Danila; Liénard Danielle; Plum Jean; MacDonald H Robson; Speiser Daniel E; Cerottini Jean-Charles; Romero Pedro
Thymic selection generates a large T cell pool recognizing a self-peptide in humans.
The Journal of experimental medicine 2002;195(4):485-94.
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2002: Ayyoub Maha; Stevanovic Stefan; Sahin Ugur; Guillaume Philippe; Servis Catherine; Rimoldi Donata; Valmori Danila; Romero Pedro; Cerottini Jean-Charles; Rammensee Hans-Georg; Pfreundschuh Michael; Speiser Daniel; Lévy Frédéric
Proteasome-assisted identification of a SSX-2-derived epitope recognized by tumor-reactive CTL infiltrating metastatic melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1717-22.
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2002: Miconnet Isabelle; Koenig Sylvain; Speiser Daniel; Krieg Arthur; Guillaume Philippe; Cerottini Jean-Charles; Romero Pedro
CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1212-8.
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2002: Dutoit Valérie; Rubio-Godoy Verena; Doucey Marie-Agnès; Batard Pascal; Liénard Danielle; Rimoldi Donata; Speiser Daniel; Guillaume Philippe; Cerottini Jean-Charles; Romero Pedro; Valmori Danila
Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1167-71.
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2001: Speiser D E; Colonna M; Ayyoub M; Cella M; Pittet M J; Batard P; Valmori D; Guillaume P; Liénard D; Cerottini J C; Romero P
The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6165-70.
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2001: Rimoldi D; Muehlethaler K; Salvi S; Valmori D; Romero P; Cerottini J C; Levy F
Subcellular localization of the melanoma-associated protein Melan-AMART-1 influences the processing of its HLA-A2-restricted epitope.
The Journal of biological chemistry 2001;276(46):43189-96.
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2001: Ayyoub M; Migliaccio M; Guillaume P; Liénard D; Cerottini J C; Romero P; Lévy F; Speiser D E; Valmori D
Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing.
European journal of immunology 2001;31(9):2642-51.
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2001: Rubio-Godoy V; Dutoit V; Rimoldi D; Lienard D; Lejeune F; Speiser D; Guillaume P; Cerottini J C; Romero P; Valmori D
Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10302-7.
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2001: Dutoit V; Rubio-Godoy V; Dietrich P Y; Quiqueres A L; Schnuriger V; Rimoldi D; Liénard D; Speiser D; Guillaume P; Batard P; Cerottini J C; Romero P; Valmori D
Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity.
Cancer research 2001;61(15):5850-6.
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2001: Pittet M J; Zippelius A; Speiser D E; Assenmacher M; Guillaume P; Valmori D; Liénard D; Lejeune F; Cerottini J C; Romero P
Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7634-40.
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2001: Miconnet I; Coste I; Beermann F; Haeuw J F; Cerottini J C; Bonnefoy J Y; Romero P; Renno T
Cancer vaccine design: a novel bacterial adjuvant for peptide-specific CTL induction.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(7):4612-9.
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2001: Robert B; Guillaume P; Luescher I; Doucey M A; Cerottini J C; Romero P; Mach J P
Redirecting anti-viral CTL against cancer cells by surface targeting of monomeric MHC class I-viral peptide conjugated to antibody fragments.
Cancer immunity : a journal of the Academy of Cancer Immunology 2001;1():2.
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2001: Pittet M J; Speiser D E; Liénard D; Valmori D; Guillaume P; Dutoit V; Rimoldi D; Lejeune F; Cerottini J C; Romero P
Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):796s-803s.
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2001: Romero P; Dutoit V; Rubio-Godoy V; Liénard D; Speiser D; Guillaume P; Servis K; Rimoldi D; Cerottini J C; Valmori D
CD8+ T-cell response to NY-ESO-1: relative antigenicity and in vitro immunogenicity of natural and analogue sequences.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):766s-772s.
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2001: Dietrich P Y; Walker P R; Quiquerez A L; Perrin G; Dutoit V; Liénard D; Guillaume P; Cerottini J C; Romero P; Valmori D
Melanoma patients respond to a cytotoxic T lymphocyte-defined self-peptide with diverse and nonoverlapping T-cell receptor repertoires.
Cancer research 2001;61(5):2047-54.
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2001: Speiser D E; Migliaccio M; Pittet M J; Valmori D; Liénard D; Lejeune F; Reichenbach P; Guillaume P; Lüscher I; Cerottini J C; Romero P
Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells.
European journal of immunology 2001;31(2):459-66.
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2001: Berset M; Cerottini J P; Guggisberg D; Romero P; Burri F; Rimoldi D; Panizzon R G
Expression of Melan-A/MART-1 antigen as a prognostic factor in primary cutaneous melanoma.
International journal of cancer. Journal international du cancer 2001;95(1):73-7.
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2001: Valmori D; Dutoit V; Rubio-Godoy V; Chambaz C; Liénard D; Guillaume P; Romero P; Cerottini J C; Rimoldi D
Frequent cytolytic T-cell responses to peptide MAGE-A10(254-262) in melanoma.
Cancer research 2001;61(2):509-12.
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2000: Rimoldi D; Rubio-Godoy V; Dutoit V; Lienard D; Salvi S; Guillaume P; Speiser D; Stockert E; Spagnoli G; Servis C; Cerottini J C; Lejeune F; Romero P; Valmori D
Efficient simultaneous presentation of NY-ESO-1/LAGE-1 primary and nonprimary open reading frame-derived CTL epitopes in melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7253-61.
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2000: Jeannin P; Renno T; Goetsch L; Miconnet I; Aubry J P; Delneste Y; Herbault N; Baussant T; Magistrelli G; Soulas C; Romero P; Cerottini J C; Bonnefoy J Y
OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway.
Nature immunology 2000;1(6):502-9.
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2000: Robert B; Guillaume P; Luescher I; Romero P; Mach J P
Antibody-conjugated MHC class I tetramers can target tumor cells for specific lysis by T lymphocytes.
European journal of immunology 2000;30(11):3165-70.
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2000: Bonelo A; Valmori D; Triponez F; Tiercy J M; Mentha G; Oberholzer J; Champagne P; Romero J F; Esposito F; Nebié I; Barbey C; Romero P; Herrera S; Corradin G; López J A
Generation and characterization of malaria-specific human CD8(+) lymphocyte clones: effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentationby liver cells.
European journal of immunology 2000;30(11):3079-88.
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2000: Migliaccio M; Amacker M; Just T; Reichenbach P; Valmori D; Cerottini J C; Romero P; Nabholz M
Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):4978-84.
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2000: González J M; Peter K; Esposito F; Nebié I; Tiercy J M; Bonelo A; Arévalo-Herrera M; Valmori D; Romero P; Herrera S; Corradin G; López J A
HLA-A*0201 restricted CD8+ T-lymphocyte responses to malaria: identification of new Plasmodium falciparum epitopes by IFN-gamma ELISPOT.
Parasite immunology 2000;22(10):501-14.
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2000: Miconnet I; Servis C; Cerottini J C; Romero P; Lévy F
Amino acid identity and/or position determines the proteasomal cleavage of the HLA-A*0201-restricted peptide tumor antigen MAGE-3271-279.
The Journal of biological chemistry 2000;275(35):26892-7.
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2000: Valmori D; Dutoit V; Liénard D; Rimoldi D; Pittet M J; Champagne P; Ellefsen K; Sahin U; Speiser D; Lejeune F; Cerottini J C; Romero P
Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients.
Cancer research 2000;60(16):4499-506.
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2000: Valmori D; Dutoit V; Liénard D; Lejeune F; Speiser D; Rimoldi D; Cerundolo V; Dietrich P Y; Cerottini J C; Romero P
Tetramer-guided analysis of TCR beta-chain usage reveals a large repertoire of melan-A-specific CD8+ T cells in melanoma patients.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):533-8.
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2000: Holler N; Kataoka T; Bodmer J L; Romero P; Romero J; Deperthes D; Engel J; Tschopp J; Schneider P
Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors.
Journal of immunological methods 2000;237(1-2):159-73.
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2000: Pittet M J; Speiser D E; Valmori D; Cerottini J C; Romero P
Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1148-52.
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2000: Valmori D; Lévy F; Miconnet I; Zajac P; Spagnoli G C; Rimoldi D; Liénard D; Cerundolo V; Cerottini J C; Romero P
Induction of potent antitumor CTL responses by recombinant vaccinia encoding a melan-A peptide analogue.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):1125-31.
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1999: Valmori D; Fonteneau J F; Valitutti S; Gervois N; Dunbar R; Liénard D; Rimoldi D; Cerundolo V; Jotereau F; Cerottini J C; Speiser D E; Romero P
Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues.
International immunology 1999;11(12):1971-80.
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1999: Speiser D E; Pittet M J; Valmori D; Dunbar R; Rimoldi D; Liénard D; MacDonald H R; Cerottini J C; Cerundolo V; Romero P
In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes.
The Journal of experimental medicine 1999;190(6):775-82.
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1999: Pittet M J; Valmori D; Dunbar P R; Speiser D E; Liénard D; Lejeune F; Fleischhauer K; Cerundolo V; Cerottini J C; Romero P
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.
The Journal of experimental medicine 1999;190(5):705-15.
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1999: Valmori D; Pittet M J; Vonarbourg C; Rimoldi D; Liénard D; Speiser D; Dunbar R; Cerundolo V; Cerottini J C; Romero P
Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376.
Cancer research 1999;59(16):4050-5.
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1999: Fleischhauer K; Agostino A; Zino E; Mazzi B; Benazzi E; Arevalo-Herrera M; Herrera S; Bordignon C; Romero P
Molecular characterization of HLA class I in Colombians carrying HLA-A2: high allelic diversity and frequency of heterozygotes at the HLA-B locus.
Tissue antigens 1999;53(6):519-26.
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1999: Speiser D E; Valmori D; Rimoldi D; Pittet M J; Liénard D; Cerundolo V; MacDonald H R; Cerottini J C; Romero P
CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients.
European journal of immunology 1999;29(6):1990-9.
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1999: Schneider P; MacKay F; Steiner V; Hofmann K; Bodmer J L; Holler N; Ambrose C; Lawton P; Bixler S; Acha-Orbea H; Valmori D; Romero P; Werner-Favre C; Zubler R H; Browning J L; Tschopp J
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.
The Journal of experimental medicine 1999;189(11):1747-56.
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1999: Valmori D; Pittet M J; Rimoldi D; Liénard D; Dunbar R; Cerundolo V; Lejeune F; Cerottini J C; Romero P
An antigen-targeted approach to adoptive transfer therapy of cancer.
Cancer research 1999;59(9):2167-73.
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1999: Men Y; Miconnet I; Valmori D; Rimoldi D; Cerottini J C; Romero P
Assessment of immunogenicity of human Melan-A peptide analogues in HLA-A*0201/Kb transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3566-73.
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1999: Valmori D; Gileadi U; Servis C; Dunbar P R; Cerottini J C; Romero P; Cerundolo V; Lévy F
Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3.
The Journal of experimental medicine 1999;189(6):895-906.
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1998: Valmori D; Gervois N; Rimoldi D; Fonteneau J F; Bonelo A; Liénard D; Rivoltini L; Jotereau F; Cerottini J C; Romero P
Diversity of the fine specificity displayed by HLA-A*0201-restricted CTL specific for the immunodominant Melan-A/MART-1 antigenic peptide.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6956-62.
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1998: Romero P; Dunbar P R; Valmori D; Pittet M; Ogg G S; Rimoldi D; Chen J L; Liénard D; Cerottini J C; Cerundolo V
Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes.
The Journal of experimental medicine 1998;188(9):1641-50.
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1998: Fleischhauer K; Zino E; Arevalo-Herrera M; Herrera S; Valmori D; Cerottini J C; Benazzi E; Bordignon C; Romero P
Differential expression of HLA-A*02 subtypes in Colombian Blacks and Mestizos.
Tissue antigens 1998;51(2):204-9.
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1998: Valmori D; Fonteneau J F; Lizana C M; Gervois N; Liénard D; Rimoldi D; Jongeneel V; Jotereau F; Cerottini J C; Romero P
Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):1750-8.
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1998: Cerottini J C; Valmori D; Rimoldi D; Romero P
Human tumor immunotherapy. New opportunities as well as new challenges.
Advances in experimental medicine and biology 1998;451():247-50.
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1997: Reed D S; Romero P; Rimoldi D; Cerottini J C; Schaack J; Jongeneel C V
Construction and characterization of a recombinant adenovirus directing expression of the MAGE-1 tumor-specific antigen.
International journal of cancer. Journal international du cancer 1997;72(6):1045-55.
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1997: Romero P; Gervois N; Schneider J; Escobar P; Valmori D; Pannetier C; Steinle A; Wolfel T; Lienard D; Brichard V; van Pel A; Jotereau F; Cerottini J C
Cytolytic T lymphocyte recognition of the immunodominant HLA-A*0201-restricted Melan-A/MART-1 antigenic peptide in melanoma.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(5):2366-74.
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1997: Waanders G A; Rimoldi D; Liénard D; Carrel S; Lejeune F; Dietrich P Y; Cerottini J C; Romero P
Melanoma-reactive human cytotoxic T lymphocytes derived from skin biopsies of delayed-type hypersensitivity reactions induced by injection of an autologous melanoma cell line.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(5):685-96.
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1997: Anjuère F; Kuznetsov D; Romero P; Cerottini J C; Jongeneel C V; Luescher I F
Differential roles of T cell receptor alpha and beta chains in ligand binding among H-2Kd-restricted cytolytic T lymphocyte clones specific for a photoreactive Plasmodium berghei circumsporozoite peptide derivative.
The Journal of biological chemistry 1997;272(13):8505-14.
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1997: Valmori D; Liénard D; Waanders G; Rimoldi D; Cerottini J C; Romero P
Analysis of MAGE-3-specific cytolytic T lymphocytes in human leukocyte antigen-A2 melanoma patients.
Cancer research 1997;57(4):735-41.
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1996: Hahne M; Rimoldi D; Schröter M; Romero P; Schreier M; French L E; Schneider P; Bornand T; Fontana A; Lienard D; Cerottini J; Tschopp J
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape.
Science (New York, N.Y.) 1996;274(5291):1363-6.
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1996: Luescher I F; Romero P; Kuznetsov D; Rimoldi D; Coulie P; Cerottini J C; Jongeneel C V
HLA photoaffinity labeling reveals overlapping binding of homologous melanoma-associated gene peptides by HLA-A1, HLA-A29, and HLA-B44.
The Journal of biological chemistry 1996;271(21):12463-71.
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1996: Herman J; van der Bruggen P; Luescher I F; Mandruzzato S; Romero P; Thonnard J; Fleischhauer K; Boon T; Coulie P G
A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3.
Immunogenetics 1996;43(6):377-83.
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1995: Romero P; Pannetier C; Herman J; Jongeneel C V; Cerottini J C; Coulie P G
Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1.
The Journal of experimental medicine 1995;182(4):1019-28.
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1995: Luescher I F; Anjuère F; Peitsch M C; Jongeneel C V; Cerottini J C; Romero P
Structural analysis of TCR-ligand interactions studied on H-2Kd-restricted cloned CTL specific for a photoreactive peptide derivative.
Immunity 1995;3(1):51-63.
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1995: Renggli J; Valmori D; Romero J F; Eberl G; Romero P; Betschart B; Corradin G
CD8+ T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: evidence that localization of peptide-specific CTLs is crucial for protection against malaria.
Immunology letters 1995;46(1-2):199-205.
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1995: Luescher I F; Vivier E; Layer A; Mahiou J; Godeau F; Malissen B; Romero P
CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes.
Nature 1995;373(6512):353-6.
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1994: da Conceição-Silva F; Perlaza B L; Louis J A; Romero P
Leishmania major infection in mice primes for specific major histocompatibility complex class I-restricted CD8+ cytotoxic T cell responses.
European journal of immunology 1994;24(11):2813-7.
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1994: Valmori D; Romero J F; Men Y; Maryanski J L; Romero P; Corradin G
Induction of a cytotoxic T cell response by co-injection of a T helper peptide and a cytotoxic T lymphocyte peptide in incomplete Freund's adjuvant (IFA): further enhancement by pre-injection of IFA alone.
European journal of immunology 1994;24(6):1458-62.
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1994: Romero P; Cerottini J C; Luescher I F
Efficient in vivo induction of CTL by cell-associated covalent H-2Kd-peptide complexes.
Journal of immunological methods 1994;171(1):73-84.
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1993: Eberl G; Sabbatini A; Servis C; Romero P; Maryanski J L; Corradin G
MHC class I H-2Kd-restricted antigenic peptides: additional constraints for the binding motif.
International immunology 1993;5(11):1489-92.
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1993: Romero P; Maryanski J L; Luescher I F
Photoaffinity labeling of the T cell receptor on living cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(9):3825-31.
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1993: Maryanski J L; Lüthy R; Romero P; Healy F; Drouet C; Casanova J L; Jaulin C; Kourilsky P; Corradin G
The interaction of antigenic peptides with the H-2Kd MHC class I molecule.
Seminars in immunology 1993;5(2):95-104.
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1992: Jaulin C; Casanova J L; Romero P; Luescher I; Cordey A S; Maryanski J L; Kourilsky P
Highly diverse T cell recognition of a single Plasmodium berghei peptide presented by a series of mutant H-2Kd molecules.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(12):3990-4.
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1992: Widmann C; Romero P; Maryanski J L; Corradin G; Valmori D
T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides.
Journal of immunological methods 1992;155(1):95-9.
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1992: Jaulin C; Romero P; Luescher I F; Casanova J L; Prochnicka-Chalufour A; Langlade-Demoyen P; Maryanski J L; Kourilsky P
Most residues on the floor of the antigen binding site of the class I MHC molecule H-2Kd influence peptide presentation.
International immunology 1992;4(8):943-53.
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1992: Rodrigues M; Nussenzweig R S; Romero P; Zavala F
The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules.
The Journal of experimental medicine 1992;175(4):895-905.
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1992: Romero P; Eberl G; Casanova J L; Cordey A S; Widmann C; Luescher I F; Corradin G; Maryanski J L
Immunization with synthetic peptides containing a defined malaria epitope induces a highly diverse cytotoxic T lymphocyte response. Evidence that two peptide residues are buried in the MHC molecule.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(6):1871-8.
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1991: Widmann C; Maryanski J L; Romero P; Corradin G
Differential stability of antigenic MHC class I-restricted synthetic peptides.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(11):3745-51.
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1991: Casanova J L; Romero P; Widmann C; Kourilsky P; Maryanski J L
T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire.
The Journal of experimental medicine 1991;174(6):1371-83.
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1991: Healy F; Drouet C; Romero P; Jaulin C; Maryanski J L
Conversion of a self peptide sequence into a Kd-restricted neo-antigen by a Tyr substitution.
The Journal of experimental medicine 1991;174(6):1657-60.
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1991: Maryanski J L; Romero P; Van Pel A; Boon T; Salemme F R; Cerottini J C; Corradin G
The identification of tyrosine as a common key residue in unrelated H-2Kd restricted antigenic peptides.
International immunology 1991;3(10):1035-42.
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1991: Romero P; Corradin G; Luescher I F; Maryanski J L
H-2Kd-restricted antigenic peptides share a simple binding motif.
The Journal of experimental medicine 1991;174(3):603-12.
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1991: Rodrigues M M; Cordey A S; Arreaza G; Corradin G; Romero P; Maryanski J L; Nussenzweig R S; Zavala F
CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria.
International immunology 1991;3(6):579-85.
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1991: Luescher I F; Romero P; Cerottini J C; Maryanski J L
Specific binding of antigenic peptides to cell-associated MHC class I molecules.
Nature 1991;351(6321):72-4.
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1991: Herrmann T; Romero P; Sartoris S; Paiola F; Accolla R S; Maryanski J L; MacDonald H R
Staphylococcal enterotoxin-dependent lysis of MHC class II negative target cells by cytolytic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(8):2504-12.
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1990: Tsuji M; Romero P; Nussenzweig R S; Zavala F
CD4+ cytolytic T cell clone confers protection against murine malaria.
The Journal of experimental medicine 1990;172(5):1353-7.
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1990: Romero P; Maryanski J L; Cordey A S; Corradin G; Nussenzweig R S; Zavala F
Isolation and characterization of protective cytolytic T cells in a rodent malaria model system.
Immunology letters 1990;25(1-3):27-31.
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1990: Herrmann T; Maryanski J L; Romero P; Fleischer B; MacDonald H R
Activation of MHC class I-restricted CD8+ CTL by microbial T cell mitogens. Dependence upon MHC class II expression of the target cells and V beta usage of the responder T cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(4):1181-6.
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1989: Romero P; Maryanski J L; Corradin G; Nussenzweig R S; Nussenzweig V; Zavala F
Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria.
Nature 1989;341(6240):323-6.
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