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Eileen Bigio

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Peter Pressman; Eileen H Bigio; Darren R Gitelman; Cindy Zadikoff
Clinical Reasoning: a woman with rapidly progressive apraxia.
Kyung-Hwa Lee; Eileen H Bigio; James P Chandler; Rohan R Lall; Qinwen Mao
Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: Case report and literature review.
Eileen H Bigio; Rakhee A Ganti; Kyung-Hwa Lee; Qinwen Mao; Manjari Mishra; Alfred Rademaker; Rosa Rademakers; Sandra Weintraub; Bing Bing Weitner; Saman S Ahmadian; Matt Baker; M-Marsel Mesulam
Frontotemporal lobar degeneration with TDP-43 proteinopathy and chromosome 9p repeat expansion in C9ORF72: clinicopathologic correlation.

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All Publications

2013: Peter Pressman; Eileen H Bigio; Darren R Gitelman; Cindy Zadikoff
Clinical Reasoning: a woman with rapidly progressive apraxia.
Neurology 2013;80(15):e162-5.
2013: Kyung-Hwa Lee; Eileen H Bigio; James P Chandler; Rohan R Lall; Qinwen Mao
Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: Case report and literature review.
Neuropathology : official journal of the Japanese Society of Neuropathology 2013;33(2):192-8.
2013: Eileen H Bigio; Rakhee A Ganti; Kyung-Hwa Lee; Qinwen Mao; Manjari Mishra; Alfred Rademaker; Rosa Rademakers; Sandra Weintraub; Bing Bing Weitner; Saman S Ahmadian; Matt Baker; M-Marsel Mesulam
Frontotemporal lobar degeneration with TDP-43 proteinopathy and chromosome 9p repeat expansion in C9ORF72: clinicopathologic correlation.
Neuropathology : official journal of the Japanese Society of Neuropathology 2013;33(2):122-33.
2013: Eileen H Bigio
Making the diagnosis of frontotemporal lobar degeneration.
Archives of pathology & laboratory medicine 2013;137(3):314-25.
2013: Eileen H Bigio; Esther N Bit-Ivan; Han-Xiang Deng; Rakhee Ganti; Changiz Geula; Qinwen Mao; Melanie Peterson; Nailah Siddique; Teepu Siddique; Jane Y Wu; Marsel Mesulam
Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid.
Acta neuropathologica 2013;125(3):463-5.
2012: Glenda Halliday; Ian R A Mackenzie; Eileen H Bigio; Nigel J Cairns; Manuela Neumann; David M A Mann
Mechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effects.
Acta neuropathologica 2012;124(3):373-82.
2012: Tamar Gefen; Changiz Geula; Mona Lalehzari; Alfred Rademaker; Emily Rogalski; Sandra Weintraub; Christina Wieneke; Eileen H Bigio; Katherine Gasho; M-Marsel Mesulam
Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia.
Brain : a journal of neurology 2012;135(Pt 5):1554-65.
2012: Eileen H Bigio
Motor neuron disease: the C9orf72 hexanucleotide repeat expansion in FTD and ALS.
Nature reviews. Neurology 2012;8(5):249-50.
2012: Kazuhiro Nakamura; Linda Nicholson; Xiao Zhen Zhou; Eileen H Bigio; Lester Binder; Sarah Denial; Alex Greenwood; Kun Ping Lu
Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease.
Cell 2012;149(1):232-44.
2012: Bradley T Hyman; Eliezer Masliah; Suzanne S Mirra; Thomas G Beach; Eileen H Bigio; Nigel J Cairns; Maria C Carrillo; Dennis W Dickson; Charles Duyckaerts; Matthew P Frosch; Peter T Nelson; Creighton H Phelps; Julie A Schneider; Dietmar R Thal; Bill Thies; John Q Trojanowski; Harry V Vinters; Thomas J Montine
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2012;8(1):1-13.
2011: Eileen H Bigio
C9ORF72, the new gene on the block, causes C9FTD/ALS: new insights provided by neuropathology.
Acta neuropathologica 2011;122(6):653-5.
2011: Richard A Armstrong; Eileen H Bigio; Felix F Cruz-Sanchez; Charles Duyckaerts; Marla Gearing; Ian R A Mackenzie; Robert H Perry; Kari Skullerud; Hideaki Yokoo; Nigel J Cairns
Spatial patterns of FUS-immunoreactive neuronal cytoplasmic inclusions (NCI) in neuronal intermediate filament inclusion disease (NIFID).
Journal of neural transmission (Vienna, Austria : 1996) 2011;118(11):1651-7.
2011: Eileen H Bigio
TDP-43 variants of frontotemporal lobar degeneration.
Journal of molecular neuroscience : MN 2011;45(3):390-401.
2011: Tristan Page; Robert H Perry; Eileen H Bigio; Nigel J Cairns; Deborah Carter; Sumi Chakraverty; Isidre Ferrer; Marla Gearing; Michael Gitcho; Alison M Goate; Sabrina Mosaheb; Julian R Thorpe
FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy.
Journal of molecular neuroscience : MN 2011;45(3):409-21.
2011: Han-Xiang Deng; Sandra Donkervoort; Faisal Fecto; George H Gorrie; Jonathan L Haines; Makito Hirano; Seong-Tshool Hong; Gerard H Jansen; Hujun Jiang; Enrico Mugnaini; Margaret Pericak-Vance; Evadnie Rampersaud; Yong Shi; Nailah Siddique; Kaouther Ajroud; Eileen H Bigio; Kym M Boycott; Benjamin R Brooks; Wenjie Chen; Robert L Sufit; Yi Yang; Hong Zhai; Teepu Siddique
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia.
Nature 2011;477(7363):211-5.
2011: Han-Xiang Deng; Faisal Fecto; Scott Heller; Manjari Mishra; Enrico Mugnaini; Yong Shi; Nailah Siddique; Kaouther Ajroud; Senda Ajroud-Driss; Eileen H Bigio; Robert Sufit; Jianhua Yan; Hong Zhai; Teepu Siddique
Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations.
Archives of neurology 2011;68(8):1057-61.
2011: Florence Dequen; Eileen H Bigio; Nigel J Cairns; Jean-Pierre Julien
Gigaxonin mutation analysis in patients with NIFID.
Neurobiology of aging 2011;32(8):1528-9.
2011: Weirui Guo; Amar Kar; Jianghong Liu; Marsel Mesulam; Elizabeth J Rao; Payal Ray; Yan Shen; Chen Wang; Meng Xu; Qi Xu; Mengxue Yang; Yanlian Yang; Haihong Ye; David Zhang; Xiaohong Zhou; Li Zhu; Eileen H Bigio; Xiaoping Chen; Yanbo Chen; Kazuo Fushimi; Jane Y Wu
An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity.
Nature structural & molecular biology 2011;18(7):822-30.
2011: Yanbo Chen; Jianwen Deng; Kazuo Fushimi; Yan Li; Jianghong Liu; Marsel Mesulam; Elizabeth J Rao; Yan Shen; Qi Xu; Mengxue Yang; Haihong Ye; Ye Ye; Xiaohong Zhou; Li Zhu; Eileen H Bigio; Xiaoping Chen; Jane Y Wu
Expression of human FUS protein in Drosophila leads to progressive neurodegeneration.
Protein & cell 2011;2(6):477-86.
2011: Ayoub Dakson; Osamu Yokota; Margaret Esiri; Eileen H Bigio; Michael Horan; Neil Pendleton; Anna Richardson; David Neary; Julie S Snowden; Andrew Robinson; Yvonne S Davidson; David M A Mann
Granular expression of prolyl-peptidyl isomerase PIN1 is a constant and specific feature of Alzheimer's disease pathology and is independent of tau, Aβ and TDP-43 pathology.
Acta neuropathologica 2011;121(5):635-49.
2011: Emily Joy Rogalski; Alfred Rademaker; Theresa M Harrison; Irene Helenowski; Nancy Johnson; Eileen H Bigio; Manjari Mishra; Sandra Weintraub; Marek-Marsel Mesulam
ApoE E4 is a susceptibility factor in amnestic but not aphasic dementias.
Alzheimer disease and associated disorders 2011;25(2):159-63.
2011: Richard A Armstrong; Marla Gearing; Eileen H Bigio; Felix F Cruz-Sanchez; Charles Duyckaerts; Ian R A Mackenzie; Robert H Perry; Kari Skullerud; Hedeaki Yokoo; Nigel J Cairns
The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease.
Acta neuropathologica 2011;121(2):219-28.
2011: Han-Xiang Deng; Eileen H Bigio; Teepu Siddique
Detection of protein aggregation in neurodegenerative diseases.
Methods in molecular biology (Clifton, N.J.) 2011;793():259-72.
2010: Arie Perry; Stephanie S Burton; Gregory N Fuller; Christopher A Robinson; Cheryl A Palmer; Lothar Resch; Eileen H Bigio; Meena Gujrati; Marc K Rosenblum
Oligodendroglial neoplasms with ganglioglioma-like maturation: a diagnostic pitfall.
Acta neuropathologica 2010;120(2):237-52.
2010: Osamu Yokota; Yvonne Davidson; Eileen H Bigio; Hideki Ishizu; Seishi Terada; Tetsuaki Arai; Masato Hasegawa; Haruhiko Akiyama; Stephen Sikkink; Stuart Pickering-Brown; D M A Mann
Phosphorylated TDP-43 pathology and hippocampal sclerosis in progressive supranuclear palsy.
Acta neuropathologica 2010;120(1):55-66.
2010: Eileen H Bigio; Manjari Mishra; Kimmo J Hatanpaa; Charles L White; Nancy Johnson; Alfred Rademaker; Bing Bing Weitner; Han-Xiang Deng; Steven D Dubner; Sandra Weintraub; Marsel Mesulam
TDP-43 pathology in primary progressive aphasia and frontotemporal dementia with pathologic Alzheimer disease.
Acta neuropathologica 2010;120(1):43-54.
2010: Han-Xiang Deng; Hong Zhai; Eileen H Bigio; Jianhua Yan; Faisal Fecto; Kaouther Ajroud; Manjari Mishra; Senda Ajroud-Driss; Scott Heller; Robert Sufit; Nailah Siddique; Enrico Mugnaini; Teepu Siddique
FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis.
Annals of neurology 2010;67(6):739-48.
2010: G Gliebus; Eileen H Bigio; K Gasho; M Mishra; D Caplan; Marek-Marsel Mesulam; Changiz Geula
Asymmetric TDP-43 distribution in primary progressive aphasia with progranulin mutation.
Neurology 2010;74(20):1607-10.
2010: Ian R A Mackenzie; Manuela Neumann; Eileen H Bigio; Nigel J Cairns; Irina Alafuzoff; Jillian Kril; Gabor Geza Kovacs; Bernardino Ghetti; Glenda Halliday; Ida E Holm; Paul Geoffrey Ince; Wouter Kamphorst; Tamas Revesz; Annemieke J M Rozemuller; Samir Kumar-Singh; Haruhiko Akiyama; Atik Baborie; Salvatore Spina; dennis dickson; John Q Trojanowski; D M A Mann
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update.
Acta neuropathologica 2010;119(1):1-4.
2009: Penelope G Foulds; Yvonne Davidson; Manjari Mishra; David J Hobson; Kirsty M Humphreys; Mark Taylor; Nancy Johnson; Sandra Weintraub; Haruhiko Akiyama; Tetsuaki Arai; Masato Hasegawa; Eileen H Bigio; Fiona E Benson; David Allsop; D M A Mann
Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration.
Acta neuropathologica 2009;118(5):647-58.
2009: Michael A Gitcho; Eileen H Bigio; Manjari Mishra; Nancy Johnson; Sandra Weintraub; Marsel Mesulam; Rosa Rademakers; Sumi Chakraverty; Carlos Cruchaga; John C Morris; Alison Goate; Nigel J Cairns
TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy.
Acta neuropathologica 2009;118(5):633-45.
2009: Ian R A Mackenzie; Manuela Neumann; Eileen H Bigio; Nigel J Cairns; Irina Alafuzoff; Jillian Kril; Gabor Geza Kovacs; Bernardino Ghetti; Glenda Halliday; Ida E Holm; Paul Geoffrey Ince; Wouter Kamphorst; Tamas Revesz; Annemieke J M Rozemuller; Samir Kumar-Singh; Haruhiko Akiyama; Atik Baborie; Salvatore Spina; dennis dickson; John Q Trojanowski; D M A Mann
Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations.
Acta neuropathologica 2009;117(1):15-8.
2008: Barbara A J Schaffer; Lars Bertram; Bruce L Miller; Kristina Mullin; Sandra Weintraub; Nancy Johnson; Eileen H Bigio; Marek-Marsel Mesulam; Martina Wiedau-Pazos; George R Jackson; Jeffrey L Cummings; Rita M Cantor; Allan Levey; Rudolph E Tanzi; Daniel Geschwind
Association of GSK3B with Alzheimer disease and frontotemporal dementia.
Archives of neurology 2008;65(10):1368-74.
2008: Fernanda G De Felice; Diana Wu; Mary P Lambert; Sara J Fernandez; Pauline T Velasco; Pascale N Lacor; Eileen H Bigio; Jasna Jerecic; Paul J Acton; Paul J Shughrue; Elizabeth Chen-Dodson; Gene G Kinney; William L Klein
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers.
Neurobiology of aging 2008;29(9):1334-47.
2008: Eileen H Bigio
TAR DNA-binding protein-43 in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer disease.
Acta neuropathologica 2008;116(2):135-40.
2008: Eileen H Bigio
Update on recent molecular and genetic advances in frontotemporal lobar degeneration.
Journal of neuropathology and experimental neurology 2008;67(7):635-48.
2008: Marek-Marsel Mesulam; Alissa Wicklund; Nancy Johnson; Emily Rogalski; Gabriel Léger; Alfred Rademaker; Sandra Weintraub; Eileen H Bigio
Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia.
Annals of neurology 2008;63(6):709-19.
2008: Kimmo J Hatanpaa; Eileen H Bigio; Nigel J Cairns; Kyle B Womack; Sandra Weintraub; John C Morris; Chan Foong; Guanghua Xiao; Christa L Hladik; Tina Y Mantanona; Charles L White
TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study.
Journal of neuropathology and experimental neurology 2008;67(4):271-9.
2008: Michael A Gitcho; Robert H Baloh; Sumi Chakraverty; Kevin Mayo; Joanne B Norton; Denise Levitch; Kimmo J Hatanpaa; Charles L White; Eileen H Bigio; Richard Caselli; Matt Baker; Muhammad T Al-Lozi; John C Morris; Alan Pestronk; Rosa Rademakers; Alison Goate; Nigel J Cairns
TDP-43 A315T mutation in familial motor neuron disease.
Annals of neurology 2008;63(4):535-8.
2008: Odity Mukherjee; Jun Wang; Michael Gitcho; Sumi Chakraverty; Lisa Taylor-Reinwald; Shantia Shears; John S K Kauwe; Joanne Norton; Denise Levitch; Eileen H Bigio; Kimmo J Hatanpaa; Charles L White; John C Morris; Nigel J Cairns; Alison Goate
Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia.
Human mutation 2008;29(4):512-21.
2007: S Davion; N Johnson; Sandra Weintraub; Marek-Marsel Mesulam; A Engberg; M Mishra; M Baker; Jennifer Adamson; Michael Hutton; Rosa Rademakers; Eileen H Bigio
Clinicopathologic correlation in PGRN mutations.
Neurology 2007;69(11):1113-21.
2007: Nigel J Cairns; Manuela Neumann; Eileen H Bigio; Ida E Holm; Dirk Troost; Kimmo J Hatanpaa; Chan Foong; Charles L White; Julie A Schneider; Hans A Kretzschmar; Deborah Carter; Lisa Taylor-Reinwald; Katherine Paulsmeyer; Jeffrey Strider; Michael Gitcho; Alison Goate; John C Morris; Manjari Mishra; Linda K Kwong; Anna Stieber; Yan Xu; Mark S Forman; John Q Trojanowski; Virginia M-Y Lee; Ian R A Mackenzie
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.
The American journal of pathology 2007;171(1):227-40.
2007: Nigel J Cairns; Eileen H Bigio; Ian R A Mackenzie; Manuela Neumann; Virginia M-Y Lee; Kimmo J Hatanpaa; Charles L White; Julie A Schneider; Lea Tenenholz Grinberg; Glenda Halliday; Charles Duyckaerts; James S Lowe; Ida E Holm; Markus Tolnay; Koichi Okamoto; Hideaki Yokoo; Shigeo Murayama; John Woulfe; David G Munoz; dennis dickson; Paul Geoffrey Ince; John Q Trojanowski; D M A Mann
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration.
Acta neuropathologica 2007;114(1):5-22.
2007: Manjari Mishra; Tatjana Paunesku; Gayle E Woloschak; Teepu Siddique; Lihua Julie Zhu; Simon Lin; Kristin Greco; Eileen H Bigio
Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions.
Acta neuropathologica 2007;114(1):81-94.
2007: Ian R A Mackenzie; Eileen H Bigio; Paul Geoffrey Ince; Felix Geser; Manuela Neumann; Nigel J Cairns; Linda K Kwong; Mark S Forman; John Ravits; Heather Stewart; Andrew Eisen; Leo McClusky; Hans A Kretzschmar; Camelia M Monoranu; J Robin Highley; Janine Kirby; Teepu Siddique; Pamela J Shaw; Virginia M-Y Lee; John Q Trojanowski
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
Annals of neurology 2007;61(5):427-34.
2007: Angela L Guillozet-Bongaarts; Kelly E Glajch; Emilie G Libson; Michael E Cahill; Eileen H Bigio; Robert W Berry; Lester I Binder
Phosphorylation and cleavage of tau in non-AD tauopathies.
Acta neuropathologica 2007;113(5):513-20.
2007: Stacey Melquist; David Craig; Matthew Huentelman; Richard Crook; John Pearson; Matt Baker; Victoria L Zismann; Jennifer Gass; Jennifer Adamson; Szabolcs Szelinger; Jason Corneveaux; Ashley Cannon; Keith D Coon; Sarah J Lincoln; Charles H Adler; Paul Tuite; Donald B Calne; Eileen H Bigio; Ryan Uitti; Zbigniew K Wszolek; Lawrence I Golbe; Richard Caselli; Neill R Graff-Radford; Irene Litvan; Matthew J Farrer; dennis dickson; Michael Hutton; Dietrich A Stephan
Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms.
American journal of human genetics 2007;80(4):769-78.
2007: Aneta Grudzien; Pamela Shaw; Sandra Weintraub; Eileen H Bigio; Deborah C Mash; Marek-Marsel Mesulam
Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease.
Neurobiology of aging 2007;28(3):327-35.
2007: Marek-Marsel Mesulam; Nancy Johnson; Thomas A Krefft; Jennifer Gass; Ashley D Cannon; Jennifer L Adamson; Eileen H Bigio; Sandra Weintraub; dennis dickson; Michael Hutton; Neill R Graff-Radford
Progranulin mutations in primary progressive aphasia: the PPA1 and PPA3 families.
Archives of neurology 2007;64(1):43-7.
2007: Mary P Lambert; Pauline T Velasco; Lei Chang; Kirsten L Viola; Sara Fernandez; Pascale LACOR; Daliya Khuon; Yuesong Gong; Eileen H Bigio; Pamela Shaw; Fernanda G De Felice; Grant A Krafft; William L Klein
Monoclonal antibodies that target pathological assemblies of Abeta.
Journal of neurochemistry 2007;100(1):23-35.
2006: Kristian T Schafernak; Eileen H Bigio
West Nile virus encephalomyelitis with polio-like paralysis & nigral degeneration.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2006;33(4):407-10.
2006: Matthew R Reynolds; Juan F Reyes; Yifan Fu; Eileen H Bigio; Angela L Guillozet-Bongaarts; Robert W Berry; Lester I Binder
Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(42):10636-45.
2006: Jennifer Gass; Ashley Cannon; Ian R A Mackenzie; Bradley Boeve; Matt Baker; Jennifer Adamson; Richard Crook; Stacey Melquist; Karen Kuntz; Ronald C. Petersen; Keith A Josephs; Stuart Pickering-Brown; Neill R Graff-Radford; Ryan Uitti; dennis dickson; Zbigniew K Wszolek; John Gonzalez; Thomas Beach; Eileen H Bigio; Nancy Johnson; Sandra Weintraub; Marek-Marsel Mesulam; Charles L White; Bryan Woodruff; Richard Caselli; Ging-Yuek Hsiung; Howard Feldman; David S. Knopman; Michael Hutton; Rosa Rademakers
Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration.
Human molecular genetics 2006;15(20):2988-3001.
2006: A-M Shiarli; R Jennings; Jing Shi; K Bailey; Yvonne Davidson; Jinzhou Tian; Eileen H Bigio; Bernardino Ghetti; Jill R Murrell; Marie-Bernadette Delisle; Suzanne S Mirra; Barbara J Crain; P Zolo; K Arima; E Iseki; S Murayama; Hans A Kretzschmar; M Neumann; Carol F Lippa; G Halliday; J Mackenzie; N Khan; Rivka Ravid; dennis dickson; Zbigniew K Wszolek; Takeshi Iwatsubo; Stuart Pickering-Brown; D M A Mann
Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease.
Neuropathology and applied neurobiology 2006;32(4):374-87.
2006: Frederick J Bonte; Thomas S Harris; Linda Hynan; Eileen H Bigio; Charles L White
Tc-99m HMPAO SPECT in the differential diagnosis of the dementias with histopathologic confirmation.
Clinical nuclear medicine 2006;31(7):376-8.
2006: Han-Xiang Deng; Yong Shi; Furukawa Yoshiaki; Hong Zhai; Ronggen Fu; Erdong Liu; George H Gorrie; Mohammad S Khan; Wu-Yen Hung; Eileen H Bigio; Thomas J Lukas; Mauro C Dal Canto; Thomas V O'Halloran; Teepu Siddique
Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(18):7142-7.
2006: Parastoo Momeni; Nigel J Cairns; Robert H Perry; Eileen H Bigio; Marla Gearing; Andrew Singleton; John Hardy
Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID).
Neurobiology of aging 2006;27(5):778.e1-778.e6.
2006: Rohan de Silva; Tammaryn Lashley; Catherine Strand; Anna-Maria Shiarli; Jing Shi; Jinzhou Tian; Kathryn L Bailey; Peter Davies; Eileen H Bigio; Kunimasa Arima; Eizo Iseki; Shigeo Murayama; Hans A Kretzschmar; Manuela Neumann; Carol F Lippa; Glenda Halliday; James MacKenzie; Rivka Ravid; dennis dickson; Zbigniew K Wszolek; Takeshi Iwatsubo; Stuart Pickering-Brown; Janice Holton; Andrew J Lees; Tamas Revesz; D M A Mann
An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies.
Acta neuropathologica 2006;111(4):329-40.
2006: Nigel J Cairns; Eileen H Bigio; Ian R A Mackenzie
Letter to the editor.
Journal of neuropathology and experimental neurology 2006;65(1):97; author reply 97-8.
2005: Sabrina Mosaheb; Julian R Thorpe; Lida Hashemzadeh-Bonehi; Eileen H Bigio; Marla Gearing; Nigel J Cairns
Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease.
Acta neuropathologica 2005;110(4):360-8.
2005: Angela L Guillozet-Bongaarts; Francisco Garcia-Sierra; Matthew R Reynolds; Peleg M Horowitz; Yifan Fu; Tianyi Wang; Michael E Cahill; Eileen H Bigio; Robert W Berry; Lester I Binder
Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease.
Neurobiology of aging 2005;26(7):1015-22.
2004: Pascale LACOR; Maria C Buniel; Lei Chang; Sara J Fernandez; Yuesong Gong; Kirsten L Viola; Mary P Lambert; Pauline T Velasco; Eileen H Bigio; Caleb E Finch; Grant A Krafft; William L Klein
Synaptic targeting by Alzheimer's-related amyloid beta oligomers.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(45):10191-200.
2004: Anne M Lipton; Charles L White; Eileen H Bigio
Frontotemporal lobar degeneration with motor neuron disease-type inclusions predominates in 76 cases of frontotemporal degeneration.
Acta neuropathologica 2004;108(5):379-85.
2004: Nigel J Cairns; Murray Grossman; Steven E Arnold; David J Burn; Evelyn Jaros; Robert H Perry; Charles Duyckaerts; B Stankoff; B Pillon; Kari Skullerud; F F Cruz-Sanchez; Eileen H Bigio; Ian R A Mackenzie; Marla Gearing; Jorge L Juncos; Jonathan D Glass; Hideaki Yokoo; Yoichi Nakazato; Sabrina Mosaheb; Julian R Thorpe; Kunihiro Uryu; Virginia M-Y Lee; John Q Trojanowski
Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease.
Neurology 2004;63(8):1376-84.
2004: Nigel J Cairns; Kunihiro Uryu; Eileen H Bigio; Ian R A Mackenzie; Marla Gearing; Charles Duyckaerts; Hideaki Yokoo; Yoichi Nakazato; Evelyn Jaros; Robert H Perry; Steven E Arnold; Virginia M-Y Lee; John Q Trojanowski
alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases.
Acta neuropathologica 2004;108(3):213-23.
2004: Kimmo J Hatanpaa; David M Blass; Olga Pletnikova; Barbara J Crain; Eileen H Bigio; J C Hedreen; Charles L White; Juan C Troncoso
Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementia.
Neurology 2004;63(3):538-42.
2004: Eileen H Bigio; Nancy A Johnson; Alfred W Rademaker; Bing B Fung; Marek-Marsel Mesulam; Nailah Siddique; Lisa Dellefave; Janice Caliendo; Stefanie Freeman; Teepu Siddique
Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associated with amyotrophic lateral sclerosis.
Journal of neuropathology and experimental neurology 2004;63(8):801-11.
2004: Nigel J Cairns; Victoria Zhukareva; Kunihiro Uryu; Bin Zhang; Eileen H Bigio; Ian R A Mackenzie; Marla Gearing; Charles Duyckaerts; Hideaki Yokoo; Yoichi Nakazato; Evelyn Jaros; Robert H Perry; Virginia M-Y Lee; John Q Trojanowski
alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease.
The American journal of pathology 2004;164(6):2153-61.
2004: Robert W Berry; A P Sweet; F A Clark; Sarita Lagalwar; B R Lapin; T Wang; S Topgi; Angela L Guillozet-Bongaarts; E J Cochran; Eileen H Bigio; Lester I Binder
Tau epitope display in progressive supranuclear palsy and corticobasal degeneration.
Journal of neurocytology 2004;33(3):287-95.
2004: Anne M Lipton; Raul Benavides; Linda Hynan; Frederick J Bonte; Thomas S Harris; Charles L White; Eileen H Bigio
Lateralization on neuroimaging does not differentiate frontotemporal lobar degeneration from Alzheimer's disease.
Dementia and geriatric cognitive disorders 2004;17(4):324-7.
2003: Myron Weiner; Linda Hynan; Bhavin Parikh; Nasir Zaki; Charles L White; Eileen H Bigio; Anne M Lipton; Kristin Martin-Cook; Doris A Svetlik; C Munro Cullum; Steven Vobach; Roger Rosenberg
Can alzheimer's disease and dementias with Lewy bodies be distinguished clinically?
Journal of geriatric psychiatry and neurology 2003;16(4):245-50.
2003: Marion Hogg; Zoran M Grujic; Matt Baker; Serpil Demirci; Angela L Guillozet; Alison P Sweet; Laura L Herzog; Sandra Weintraub; Marek-Marsel Mesulam; Nichole E LaPointe; T Chris Gamblin; Robert W Berry; Lester I Binder; Rohan de Silva; Andrew J Lees; Marisol Espinoza; Peter Davies; Andrew Grover; Naruhiko Sahara; Takashi Ishizawa; dennis dickson; Shu-Hui C. Yen; Michael Hutton; Eileen H Bigio
The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy.
Acta neuropathologica 2003;106(4):323-36.
2003: Eileen H Bigio; Anne M Lipton; Charles L White; dennis dickson; Asao Hirano
Frontotemporal and motor neurone degeneration with neurofilament inclusion bodies: additional evidence for overlap between FTD and ALS.
Neuropathology and applied neurobiology 2003;29(3):239-53.
2003: Michael J Strong; Catherine Lomen-Hoerth; Richard Caselli; Eileen H Bigio; Wencheng Yang
Cognitive impairment, frontotemporal dementia, and the motor neuron diseases.
Annals of neurology 2003;54 Suppl 5():S20-3.
2003: Eileen H Bigio; Joan S Reisch; Charles L White; Sivapong Satumtira; Estelle Sontag; Frederick J Bonte
Synapse loss may be a minor contributor to decreased regional cerebral blood flow in Alzheimer disease.
Dementia and geriatric cognitive disorders 2003;15(2):72-8.
2002: Huw R Morris; M Baker; K Yasojima; Henry Houlden; M Nadeem Khan; Nicholas W Wood; John Hardy; Murray Grossman; John Q Trojanowski; Tamas Revesz; Eileen H Bigio; C Bergeron; John C Janssen; Patrick L McGeer; Martin N Rossor; Andrew J Lees; Peter L Lantos; Michael Hutton
Analysis of tau haplotypes in Pick's disease.
Neurology 2002;59(3):443-5.
2002: Eileen H Bigio; Linda Hynan; Estelle Sontag; Sivapong Satumtira; Charles L White
Synapse loss is greater in presenile than senile onset Alzheimer disease: implications for the cognitive reserve hypothesis.
Neuropathology and applied neurobiology 2002;28(3):218-27.
2002: Jaime L Oeberst; Jeffrey J Barnard; Eileen H Bigio; Joseph A Prahlow
Neurocysticercosis.
The American journal of forensic medicine and pathology 2002;23(1):31-5.
2001: Anne M Lipton; C Munro Cullum; Sivapong Satumtira; Estelle Sontag; Linda Hynan; Charles L White; Eileen H Bigio
Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementias.
Archives of neurology 2001;58(8):1233-9.
2001: Henry Houlden; M Baker; H R Morris; N MacDonald; S Pickering-Brown; Jennifer Adamson; Andrew J Lees; Martin N Rossor; Niall Quinn; A Kertesz; M N Khan; John Hardy; P L Lantos; P St George-Hyslop; David G Munoz; D M A Mann; Anthony E Lang; C Bergeron; Eileen H Bigio; Irene Litvan; K P Bhatia; dennis dickson; Nicholas W Wood; Michael Hutton
Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype.
Neurology 2001;56(12):1702-6.
2001: Eileen H Bigio; M B Vono; Sivapong Satumtira; Jennifer Adamson; Estelle Sontag; Linda Hynan; Charles L White; M Baker; Michael Hutton
Cortical synapse loss in progressive supranuclear palsy.
Journal of neuropathology and experimental neurology 2001;60(5):403-10.
2001: Eileen H Bigio; Anne M Lipton; Shu-Hui C. Yen; Michael Hutton; M Baker; Parimala Nacharaju; Charles L White; Peter Davies; W Lin; dennis dickson
Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementia.
Journal of neuropathology and experimental neurology 2001;60(4):328-41.
2000: Ramon Diaz-Arrastia; Mark A Agostini; Alan B Frol; Bruce E Mickey; James L Fleckenstein; Eileen H Bigio; Paul C Van Ness
Neurophysiologic and neuroradiologic features of intractable epilepsy after traumatic brain injury in adults.
Archives of neurology 2000;57(11):1611-6.
2000: Lawrence Honig; D D Chambliss; Eileen H Bigio; S L Carroll; Jeffrey L Elliott
Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls.
Neurology 2000;55(8):1082-8.
1999: Eileen H Bigio; DF Brown; Charles L White
Progressive supranuclear palsy with dementia: cortical pathology.
Journal of neuropathology and experimental neurology 1999;58(4):359-64.
1999: Matt Baker; Irene Litvan; Henry Houlden; Jennifer Adamson; dennis dickson; Jordi Perez-Tur; John Hardy; Timothy Lynch; Eileen H Bigio; Michael Hutton
Association of an extended haplotype in the tau gene with progressive supranuclear palsy.
Human molecular genetics 1999;8(4):711-5.
1999: Eileen H Bigio; S M Colvin; Bruce E Mickey; Charles L White; Elisabeth J Rushing
Radiation change versus recurrent astrocytoma: diagnostic utility of the proliferation index?
Journal of neuro-oncology 1999;41(1):55-63.
1998: DF Brown; RC Risser; Eileen H Bigio; P Tripp; A Stiegler; E Welch; KP Eagan; Christa L Hladik; Charles L White
Neocortical synapse density and Braak stage in the Lewy body variant of Alzheimer disease: a comparison with classic Alzheimer disease and normal aging.
Journal of neuropathology and experimental neurology 1998;57(10):955-60.
1998: Ayalla Barnea; N Aguila-Mansilla; Eileen H Bigio; C Worby; Jodie Roberts
Evidence for regulated expression of neuropeptide Y gene by rat and human cultured astrocytes.
Regulatory peptides 1998;75-76():293-300.
1998: Elisabeth J Rushing; J A White; M D D' Alise; David P Chason; Charles L White; Eileen H Bigio
Primary epithelioid hemangioendothelioma of the clivus.
Clinical neuropathology 1998;17(2):110-4.
1998: Eileen H Bigio; C S Fontaine; MA Dababo; Joseph A Prahlow; David P Chason; Myron Weiner; Charles L White
Dementia associated with cortical dysplasia.
Acta neuropathologica 1998;95(2):193-8.
1998: DF Brown; MA Dababo; Eileen H Bigio; RC Risser; KP Eagan; Christa L Hladik; Charles L White
Neuropathologic evidence that the Lewy body variant of Alzheimer disease represents coexistence of Alzheimer disease and idiopathic Parkinson disease.
Journal of neuropathology and experimental neurology 1998;57(1):39-46.
1997: Elisabeth J Rushing; Jeffrey J Barnard; Eileen H Bigio; KP Eagan; Charles L White
Frequency of unilateral and bilateral mesial temporal sclerosis in primary and secondary epilepsy: a forensic autopsy study.
The American journal of forensic medicine and pathology 1997;18(4):335-41.
1997: Eileen H Bigio; Myron Weiner; Frederick J Bonte; Charles L White
Familial dementia due to adult polyglucosan body disease.
Clinical neuropathology 1997;16(4):227-34.
1997: Frederick J Bonte; Myron Weiner; Eileen H Bigio; Charles L White
Brain blood flow in the dementias: SPECT with histopathologic correlation in 54 patients.
Radiology 1997;202(3):793-7.
1994: S Pardue; Charles L White; Eileen H Bigio; Marcelle Morrison-Bogorad
Anomalous binding of radiolabeled oligonucleotide probes to plaques and tangles in Alzheimer disease hippocampus.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1994;22(1):1-24.
1993: Frederick J Bonte; R Tintner; Myron Weiner; Eileen H Bigio; Charles L White
Brain blood flow in the dementias: SPECT with histopathologic correlation.
Radiology 1993;186(2):361-5.
1990: Vicki J Schnadig; Eileen H Bigio; WK Gourley; G D Stewart; G A Newton; J M Shabot
Identification of Campylobacter pylori by endoscopic brush cytology.
Diagnostic cytopathology 1990;6(4):227-34.
1989: Eileen H Bigio; Abida K Haque
Disseminated cytomegalovirus infection presenting with acalculous cholecystitis and acute pancreatitis.
Archives of pathology & laboratory medicine 1989;113(11):1287-9.